LOCUS       DAVLBN010000001        73924 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLBN010000001 DAVLBN010000000
VERSION     DAVLBN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 73924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.001"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(405..1601)
                     /gene="tuf"
                     /locus_tag="VXC24_000001"
     CDS             complement(405..1601)
                     /gene="tuf"
                     /locus_tag="VXC24_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0492194.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2512..3381)
                     /locus_tag="VXC24_000002"
     CDS             complement(2512..3381)
                     /locus_tag="VXC24_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0492195.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3605..4213)
                     /locus_tag="VXC24_000003"
     CDS             complement(3605..4213)
                     /locus_tag="VXC24_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0492196.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4171..5277)
                     /locus_tag="VXC24_000004"
     CDS             complement(4171..5277)
                     /locus_tag="VXC24_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0492197.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5388..5642)
                     /locus_tag="VXC24_000005"
     CDS             complement(5388..5642)
                     /locus_tag="VXC24_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492198.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5982..6428)
                     /locus_tag="VXC24_000006"
     CDS             complement(5982..6428)
                     /locus_tag="VXC24_000006"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492199.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6501..6826)
                     /locus_tag="VXC24_000007"
                     /pseudo
     CDS             complement(6501..6826)
                     /locus_tag="VXC24_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7060..8778
                     /locus_tag="VXC24_000008"
     CDS             7060..8778
                     /locus_tag="VXC24_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0492200.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            8889..9236
                     /locus_tag="VXC24_000009"
     CDS             8889..9236
                     /locus_tag="VXC24_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0492201.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(9515..10351)
                     /locus_tag="VXC24_000010"
     CDS             complement(9515..10351)
                     /locus_tag="VXC24_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0492202.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10364..10993)
                     /locus_tag="VXC24_000011"
     CDS             complement(10364..10993)
                     /locus_tag="VXC24_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0492203.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11003..11644)
                     /locus_tag="VXC24_000012"
     CDS             complement(11003..11644)
                     /locus_tag="VXC24_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0492204.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11790..13019)
                     /locus_tag="VXC24_000013"
     CDS             complement(11790..13019)
                     /locus_tag="VXC24_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0492205.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13009..14175)
                     /locus_tag="VXC24_000014"
     CDS             complement(13009..14175)
                     /locus_tag="VXC24_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0492206.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14319..15332
                     /locus_tag="VXC24_000015"
     CDS             14319..15332
                     /locus_tag="VXC24_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0492207.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15377..15796)
                     /locus_tag="VXC24_000016"
     CDS             complement(15377..15796)
                     /locus_tag="VXC24_000016"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0492208.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15807..17213)
                     /gene="atpD"
                     /locus_tag="VXC24_000017"
     CDS             complement(15807..17213)
                     /gene="atpD"
                     /locus_tag="VXC24_000017"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0492209.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17299..18177)
                     /locus_tag="VXC24_000018"
     CDS             complement(17299..18177)
                     /locus_tag="VXC24_000018"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0492210.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18193..19698)
                     /locus_tag="VXC24_000019"
     CDS             complement(18193..19698)
                     /locus_tag="VXC24_000019"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0492211.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19713..20249)
                     /locus_tag="VXC24_000020"
     CDS             complement(19713..20249)
                     /locus_tag="VXC24_000020"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0492212.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20249..20743)
                     /gene="atpF"
                     /locus_tag="VXC24_000021"
     CDS             complement(20249..20743)
                     /gene="atpF"
                     /locus_tag="VXC24_000021"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0492213.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20757..21473)
                     /gene="atpB"
                     /locus_tag="VXC24_000022"
     CDS             complement(20757..21473)
                     /gene="atpB"
                     /locus_tag="VXC24_000022"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0492214.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21508..21708)
                     /locus_tag="VXC24_000023"
     CDS             complement(21508..21708)
                     /locus_tag="VXC24_000023"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0492215.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21783..22790)
                     /locus_tag="VXC24_000024"
                     /pseudo
     CDS             complement(21783..22790)
                     /locus_tag="VXC24_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23211..23609)
                     /locus_tag="VXC24_000025"
     CDS             complement(23211..23609)
                     /locus_tag="VXC24_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492216.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(23891..24373)
                     /gene="greA"
                     /locus_tag="VXC24_000026"
     CDS             complement(23891..24373)
                     /gene="greA"
                     /locus_tag="VXC24_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0492217.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(24444..26099)
                     /gene="mltG"
                     /locus_tag="VXC24_000027"
     CDS             complement(24444..26099)
                     /gene="mltG"
                     /locus_tag="VXC24_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0492218.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(26180..26674)
                     /locus_tag="VXC24_000028"
     CDS             complement(26180..26674)
                     /locus_tag="VXC24_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492219.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(26671..27135)
                     /locus_tag="VXC24_000029"
     CDS             complement(26671..27135)
                     /locus_tag="VXC24_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492220.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(27145..28479)
                     /locus_tag="VXC24_000030"
     CDS             complement(27145..28479)
                     /locus_tag="VXC24_000030"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0492221.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(28490..29107)
                     /locus_tag="VXC24_000031"
     CDS             complement(28490..29107)
                     /locus_tag="VXC24_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0492222.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(29155..32253)
                     /locus_tag="VXC24_000032"
     CDS             complement(29155..32253)
                     /locus_tag="VXC24_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0492223.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(32346..33512)
                     /locus_tag="VXC24_000033"
     CDS             complement(32346..33512)
                     /locus_tag="VXC24_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0492224.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            complement(33520..34614)
                     /locus_tag="VXC24_000034"
     CDS             complement(33520..34614)
                     /locus_tag="VXC24_000034"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0492225.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            complement(34772..36454)
                     /locus_tag="VXC24_000035"
                     /pseudo
     CDS             complement(34772..36454)
                     /locus_tag="VXC24_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(36626..38584)
                     /locus_tag="VXC24_000036"
     CDS             complement(36626..38584)
                     /locus_tag="VXC24_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0492226.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(38787..40409)
                     /locus_tag="VXC24_000037"
     CDS             complement(38787..40409)
                     /locus_tag="VXC24_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0492227.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40515..41960
                     /locus_tag="VXC24_000038"
     CDS             40515..41960
                     /locus_tag="VXC24_000038"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0492228.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(42006..42200)
                     /locus_tag="VXC24_000039"
     CDS             complement(42006..42200)
                     /locus_tag="VXC24_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0492229.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(42301..42909)
                     /locus_tag="VXC24_000040"
     CDS             complement(42301..42909)
                     /locus_tag="VXC24_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0492230.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(42934..43446)
                     /locus_tag="VXC24_000041"
     CDS             complement(42934..43446)
                     /locus_tag="VXC24_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0492231.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            complement(43532..44467)
                     /locus_tag="VXC24_000042"
     CDS             complement(43532..44467)
                     /locus_tag="VXC24_000042"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0492232.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(44538..44837)
                     /locus_tag="VXC24_000043"
     CDS             complement(44538..44837)
                     /locus_tag="VXC24_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0492233.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(44827..45576)
                     /locus_tag="VXC24_000044"
     CDS             complement(44827..45576)
                     /locus_tag="VXC24_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0492234.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(45630..45989)
                     /locus_tag="VXC24_000045"
     CDS             complement(45630..45989)
                     /locus_tag="VXC24_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0492235.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(45991..47391)
                     /locus_tag="VXC24_000046"
     CDS             complement(45991..47391)
                     /locus_tag="VXC24_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0492236.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(47686..47925)
                     /locus_tag="VXC24_000047"
     CDS             complement(47686..47925)
                     /locus_tag="VXC24_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0492237.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(47957..48427)
                     /gene="ssbA"
                     /locus_tag="VXC24_000048"
     CDS             complement(47957..48427)
                     /gene="ssbA"
                     /locus_tag="VXC24_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0492238.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(48439..48729)
                     /locus_tag="VXC24_000049"
     CDS             complement(48439..48729)
                     /locus_tag="VXC24_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0492239.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(48882..50228)
                     /gene="asnS"
                     /locus_tag="VXC24_000050"
     CDS             complement(48882..50228)
                     /gene="asnS"
                     /locus_tag="VXC24_000050"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0492240.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(50244..50609)
                     /locus_tag="VXC24_000051"
     CDS             complement(50244..50609)
                     /locus_tag="VXC24_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0492241.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(50602..51789)
                     /locus_tag="VXC24_000052"
     CDS             complement(50602..51789)
                     /locus_tag="VXC24_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0492242.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(51786..52274)
                     /locus_tag="VXC24_000053"
     CDS             complement(51786..52274)
                     /locus_tag="VXC24_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0492243.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            52595..53143
                     /locus_tag="VXC24_000054"
     CDS             52595..53143
                     /locus_tag="VXC24_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0492244.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(53420..54148)
                     /gene="yaaA"
                     /locus_tag="VXC24_000055"
     CDS             complement(53420..54148)
                     /gene="yaaA"
                     /locus_tag="VXC24_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0492245.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(54227..54391)
                     /locus_tag="VXC24_000056"
     CDS             complement(54227..54391)
                     /locus_tag="VXC24_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0492246.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(54458..56053)
                     /locus_tag="VXC24_000057"
     CDS             complement(54458..56053)
                     /locus_tag="VXC24_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492247.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(56065..56475)
                     /locus_tag="VXC24_000058"
     CDS             complement(56065..56475)
                     /locus_tag="VXC24_000058"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0492248.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(56591..57382)
                     /gene="yghU"
                     /locus_tag="VXC24_000059"
     CDS             complement(56591..57382)
                     /gene="yghU"
                     /locus_tag="VXC24_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0492249.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(57395..60091)
                     /locus_tag="VXC24_000060"
     CDS             complement(57395..60091)
                     /locus_tag="VXC24_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0492250.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            60395..61579
                     /gene="mntE"
                     /locus_tag="VXC24_000061"
     CDS             60395..61579
                     /gene="mntE"
                     /locus_tag="VXC24_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0492251.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(61722..63593)
                     /locus_tag="VXC24_000062"
     CDS             complement(61722..63593)
                     /locus_tag="VXC24_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0492252.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(63590..64774)
                     /locus_tag="VXC24_000063"
     CDS             complement(63590..64774)
                     /locus_tag="VXC24_000063"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0492253.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(64786..65553)
                     /locus_tag="VXC24_000064"
     CDS             complement(64786..65553)
                     /locus_tag="VXC24_000064"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0492254.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(65830..66678)
                     /locus_tag="VXC24_000065"
     CDS             complement(65830..66678)
                     /locus_tag="VXC24_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0492255.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(66680..67054)
                     /locus_tag="VXC24_000066"
     CDS             complement(66680..67054)
                     /locus_tag="VXC24_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0492256.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(67128..68480)
                     /locus_tag="VXC24_000067"
     CDS             complement(67128..68480)
                     /locus_tag="VXC24_000067"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0492257.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(68504..69283)
                     /locus_tag="VXC24_000068"
     CDS             complement(68504..69283)
                     /locus_tag="VXC24_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0492258.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(69270..70127)
                     /locus_tag="VXC24_000069"
     CDS             complement(69270..70127)
                     /locus_tag="VXC24_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0492259.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            70263..71231
                     /locus_tag="VXC24_000070"
     CDS             70263..71231
                     /locus_tag="VXC24_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0492260.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(71483..72439)
                     /locus_tag="VXC24_000071"
     CDS             complement(71483..72439)
                     /locus_tag="VXC24_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0492261.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(72443..72775)
                     /locus_tag="VXC24_000072"
     CDS             complement(72443..72775)
                     /locus_tag="VXC24_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0492262.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            complement(72779..73078)
                     /locus_tag="VXC24_000073"
     CDS             complement(72779..73078)
                     /locus_tag="VXC24_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492263.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(73088..73438)
                     /locus_tag="VXC24_000074"
     CDS             complement(73088..73438)
                     /locus_tag="VXC24_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492264.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            complement(73441..73644)
                     /locus_tag="VXC24_000075"
     CDS             complement(73441..73644)
                     /locus_tag="VXC24_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492265.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITNNILSIQLDEQREGNQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(73739..>73924)
                     /locus_tag="VXC24_000076"
     CDS             complement(73739..>73924)
                     /locus_tag="VXC24_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0492266.1"
                     /translation="KHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIK
                     AIQELNQKIEKMEKTIA"
BASE COUNT        21405 a        16506 c        13776 g        22237 t
ORIGIN      
        1 ttcttcttta gttgatttca tattactatt gtataatgct ttttgatttg agtctagtat
       61 tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat agatgttact
      121 gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg cagctaactt
      181 tctataacaa aatgaaataa gaacaagaca aatcaatcaa gacaatcaaa tcgatttcta
      241 agaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag tttgctcttt
      301 gattttcatt tagtattagt tcaatatcta aaaaaagaac cttgccaagc aagattcttt
      361 tagtgtctga cttaaataat tgttcttctg ggaactaaat cgaattaagc ttcgatttct
      421 gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt agtaccttgt
      481 tctacggcga ttgggtgaat caactcaaca tcgattgtca cgttatcacc aggcattacc
      541 atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg gaagtagaat
      601 tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt agtaaggatg
      661 tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc gataacttgt
      721 ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt atctccagca
      781 agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc tttttgagtt
      841 tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc acggtcgata
      901 cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
      961 aatggtttgt cagtgtcacg ttctggttct gggatatact catcaactgt gttcatcaat
     1021 tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc tgaaccttgg
     1081 ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg gatttccatt
     1141 tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat gaagacgata
     1201 aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
     1261 ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc agtgatcatg
     1321 tttttaacgt agtccgcgtg tcctggagcg tcgatgtgag cgtagtgacg tttttcagtt
     1381 tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc tggagcagca
     1441 tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg tgccaaaaca
     1501 gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat agtaccaatg
     1561 ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa agcctccaat
     1621 aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta ctattttatc
     1681 aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct tggtaaaaat
     1741 ttaactaact aatagaaagt actaaataga cttatccttc aaggagtttt cagcattatc
     1801 catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa atgaaacaag
     1861 aatagggcaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagttaagg
     1921 tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga acaacctgcg
     1981 gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga taaaacgata
     2041 acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct aatcgcttat
     2101 tttatagcaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat caattcctca
     2161 caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa gcagacttac
     2221 aagataggga acccatctcc gataatatat agtagaatga aaactgcaca atttgattgg
     2281 agaattcaaa ccaatttcta acaatgtttt agaaacaagg gtctattatt tcaactgcaa
     2341 cctactatag cccattgaag ctggaatagc ccactgagac ttctaaacca ctgctggaga
     2401 ggagtttgtt tagagtttct ttcatttccc taaaaaatca aaaagagaga accagtctga
     2461 tcctctctta cttatagatg gtgctcactc aaatgttaaa ggagctattt cttagagata
     2521 aaggaatttg aatacagcta ctgccgcaat tgctgctgcg ataggtgcta ctactggtac
     2581 ccaagaatac caccattttg aatcgccttt atgctcacca agaactgatt ttggaaggaa
     2641 agcatgaagg agacgtggtc ccaagtcacg ggctgggttc aaggcaggtc ctgtaggtcc
     2701 tccaagtgat gttaccaaag ccataacgag gaatccaagt gccaagtgag ccacagaaag
     2761 tcctgaagca gtgtgtggag ccacctgtgc tttaatagcc aagtcagaaa aatcaactgt
     2821 ttgtcctgct tctattgcct tttgtttcat gaattgaagc acttcagcac caaagaagtt
     2881 tttagtcaaa ccaagagctg caaagaacaa aacaaatgaa ccaacaaact cattaatcaa
     2941 accattgaca gttgctgcat agcgactttc ttttgtacca tggtcaatac ttgaaatagt
     3001 tgagaaagtt cccaagatgt tatttgggtt ttcagttttc aagtagaatg gacggtatgt
     3061 tgccacaact aaggcttggc caaagatagc ccccaagact tgcgcgataa tgtaaggtac
     3121 cacttgtgcc caagggaaaa gaccgctaac tgcaagccct agagtgaaag cagggttgat
     3181 gtgattccca gatacgttac caaacatcaa ggctgggatc ataaccccca taccataacc
     3241 aacagcgatg acgatccagc cactttggtg acctttcgta cctttaagtt caacgttggc
     3301 aactgcacca ttcccaagaa tgatcaaaat ggcagttccc aaaaattcag tggcatactt
     3361 cagtgcccat gtgaaatcca tttgctagat tctccttaaa attttttaga tattccttat
     3421 tttatcaatt tttaccctat ttagcaactg atttctggaa atatttttaa aaaaatagga
     3481 ttcatagttt cccagttcaa cagacttgta agcgttttta ttctttacga aagacctcgt
     3541 tctcaaaacc aggaaaaaag cccacatctg tgagcttttc ctggttccta gattctaaaa
     3601 tctattattt ttcatcttct tttttcttga aaaatcctaa tcctagacca gctaacaagg
     3661 tcatgatacc agcactagcc aaggtagcat tagcttctgt acctgtgttt ggcaattcct
     3721 ctctcttacc tgtctcataa gtcggaactt ctgggtctgg attcactgga gtttcagttt
     3781 ttggagtacc tggttctgga gttggtttat ctggtgttgg agtctcttga tttggtagtt
     3841 ctgggtttgg tgtcggaaca cttggatgct ctggatttgg ttgtgggatt ggtttttctg
     3901 gtgttgataa acggtcatac cttaccgtta tttctttatc actagagtct gacgtaactt
     3961 cttgtgattc aactgttgga atatctggat ctttgtactt gtcaatctta ccagatataa
     4021 cctcgtccca gtttcctgtt gtccattcac cgtaggttac aactcccgtg accttgttct
     4081 cagtttttgt acggcttaag gttacaggtt gaacaacatc ttcttttaca ttttggttcg
     4141 taactttatc aacgtaatga atgatacgcg ttatagtctt cgtctcagta gaggttgctg
     4201 ttttgggaac cactgtttcc tcaacattct cacggtagta atagtcaact gttgcaccgt
     4261 cttctggtac gcatttgcag gagttgctac caaggtgtat gttgttttcc ttgtgataac
     4321 tcggtcttct ttgtcctcag ttgttgtttt cccttcaata gtttttgatt ctgtggtata
     4381 ctcagaacct atcgctaaat cagcttttat aacagactct accaacttct cttgcctacc
     4441 ttctttatag taattggctg ttactgtagc agtggttggc gcttcgcttt ctctataaac
     4501 taaggtcact gttctacctt cgcttacaat attcccagtt aaacttgcag aatttgtatc
     4561 tgcttcttta aaagtataat attttccgtc agtagtagtc atgctactga gttttttatc
     4621 tgtgacattg tagctggtac caatcagttg ttttttattg gtaatgtagg ttccgtcact
     4681 ttctttttct ccaattccag tatcattttt caatgatagc aaacgccctt gttcatcaac
     4741 atagcgaact ttcacatttt ctgagattag ttctgccaat tctgaggttt ttttcttttt
     4801 cttgatttct tcggttattt tccctttctc ttcttcggga atatttagtt ttggaatgat
     4861 tttttcaaca acggttcgtg atggttccac agtatcttgg atgactgaaa agtcagctag
     4921 aattgggaga ttatactgaa cacggtgact ttgagtgttt actcctactc tttcattatt
     4981 ctctgaaaat acttgtacgg tataagaaac aacatctttt cctaatagaa catccccagt
     5041 agagaaatag ccgccttttc ctagtttgct atctccagag cccacttctt tcctaatctt
     5101 atcagatagt tttttaccag tcagtacatt cgttcgcaca atccctttgt ctacccctac
     5161 aaagtgggag aactttttga actcttcaga accagatcta gcccaaccat tattaagggc
     5221 atttgctttt gtatttgtat tctctctcaa aagtttggcg attagaatta tattcatcgg
     5281 cacttagagt tgctgctata tctgactctt gaataccaac ttccttacta ccatttctag
     5341 cggcagtata tgtgtattta tctgtttcta cttctagctg attatcctta acatgatagg
     5401 taattttctc ctggtataag agtcttcagt agtttatatg ctctgtcatc atctttagct
     5461 ttagaagcag ctgagtttag ccaagttggg gtattaggag tatctttatc agcctgtttc
     5521 aagacattat tcaagtcatt tgctagccta ttggttgtcc tcactgtgaa agttttcttc
     5581 cagtctgaac cacttttatt agacttagat atgctcatga aatcctggtc aacattcaac
     5641 acaatatcgc cttgtttttt agcatcttcc gttgcttctg cttcaaattg atcatggagt
     5701 ttttgttgct ctggtgtata gtttttttat ttacacgatt taatgtacta ttttttattt
     5761 tagtattaag aactccatta atacgatttt taaactctgc ttcaaaaaat cccttaattt
     5821 gttggtgcgc aagttcaaca ttcaaacctt ttttatacaa gtcttcattc tgaacgattt
     5881 cggctacacg gtgaatggtt tgattgtata ccgtcttctc ttaaccagca gtatccttag
     5941 ttttaatgac tactcgatag gttcctttag aaccgttata gtcatctagt tttaaaaaag
     6001 cattccaaac attcaaaaat agttggaact tcccttaata aatccgtcac tttctttttc
     6061 aagatagccc aagcttgctc aataggattc aaatccggtg aataaggtgg tagaggtaag
     6121 aaaaagtgtt tatcttggat gcagagttca tccaaaatgt tcttgggatg aaaaccagca
     6181 ttgcccatga caataacatg aggtgtcttc aaagcaggta ggagttgcgt tttgaaccac
     6241 tccacaaaga aatcgcttgt catgcttttc ttgtaaatca tgggagctat aaactctccg
     6301 tctacttgtc ctgcaacaat tgaaattcgc tcaaaacgac gtccgctaat cttttcatag
     6361 actttctccc ctctaggagc ccctgcataa ggacgataga gatagcggtc gattcctgtt
     6421 tcatcaatat aaacaggtgc taggtgcttt aaactattaa aattcttaag aaataaggct
     6481 acttttctgg gtcttgttcc ttaaagctcg tcatcttttt ttaaagtgac cttaatctgc
     6541 tttaaagctg cccatactga aggaacagca caatcaaaat gtgccgcaat ttcccgtaaa
     6601 aaagcatctg gatgagcctc tacaaaggct ttcaattcct ctaaaggaat ctttcggttt
     6661 ttgacgactc gctttttcct ctctatgtgt tcttgttcac gtctttcttt tcccacgtga
     6721 agagagttct gacgccaaca ccaaaaaact tggctgcctc gacatggctg tgcccctctt
     6781 tgatgtaatc taatgctcgc tgtttaaaat cagtactata tgccatagct ttattataat
     6841 atgcttgttt aaaactaagt aactatatca atgttttgtt atgagaagac ttactttttt
     6901 tactgaaatt gaatttttcc tagcctaaac atcatataac cccaaaattc aatctgacct
     6961 ggtttgaaga gattttcgaa gcagataagg ttttactaaa actaaaaaaa atgatataat
     7021 caaactgatt aaatgtttta aaaataaagg agaatttgaa tgtcttacca agaaaattac
     7081 cagaaatggg ttgattttgt ggagcttcct gactaccttc gtcaagattt ggaaaatatg
     7141 gacgaaaaaa ctaaggaaga tgccttctat acaaatcttg aatttggtac tgcaggtatg
     7201 cgtggcttgg ttggtgctgg tacaaaccgt atcaacatct acgttgttcg ccaagctact
     7261 gaaggattgg ctcgtttgat tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca
     7321 attgcctacg atagccgtca cttctcacct gagtttgcct ttgaatctgc ggcagttctt
     7381 gctaaacacg gcatcaaatc ttacgtattt gaaagccttc gtccaactcc agaactatca
     7441 tttgcagttc gtcatctcaa ctgtttcgca ggtatcatgg tcacagccag ccacaaccct
     7501 gctccattta acggttacaa ggtttacggt gaagacggtg gacaaatgcc tccacacgat
     7561 gcggacgctt tgactactta tatccgtgca atcgaaaacc catttgcagt tgaagttgct
     7621 gatgtggaaa ctgaaaaagc ttctggcttg attgaagtta tcggcgaagc tgttgacata
     7681 gaatacctta aagaggttaa ggacataaac atcaacccag ccttgattga agaatttggt
     7741 aaagacatga agattgtcta cacaccactt catggtactg gtgaaatgtt ggctcgtcgt
     7801 gctcttgccc aagcaggatt tgactctgtt caagttgttg aagcgcaagc aactgctgac
     7861 ccagacttct caactgtaac atctccaaac ccagaaagcc aagcagcctt tgcccttgct
     7921 gaagaacttg gtcgtcaagt tggtgcagat gttcttgtcg caactgaccc agacgctgac
     7981 cgtgttggtg ttgaagttct tcaaaaagat ggcagctacc tcaacctttc aggtaaccaa
     8041 atcggtgcta tcatggctaa atacatcttg gaagctcaca aaaacgctgg aactcttcct
     8101 gaaaatgccg ctctctgcaa atctatcgtt tcaactgact tggtaacgaa gattgctgaa
     8161 agctacggcg caactatgtt caacgtcttg acaggtttca aatttatcgc tgaaaaaatc
     8221 caagaattcg aagaaaaaca caaccacact tacatgatgg gatttgaaga aagcttcggt
     8281 tacttgatta aaccatttgt acgtgataaa gatgccatcc aagccgttct tgtagttgct
     8341 gaacttgctg cctactaccg ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc
     8401 tataaagaat atggctacta cgcagaaaaa acaatctctg ttactctttc aggtgtcgat
     8461 ggtgctgaac aaatcaaagc gattatggct aaattccgca acaatgctcc aacagaatgg
     8521 aacgcaacag ctatcactgt cgtagaagac ttcaaggcac aaactgctac tgttgctgac
     8581 ggtactgtta caaacttgac aactcctcca agtgatgtgt tgaaatacac acttgctgac
     8641 ggttcatgga ttgccgttcg cccttcaggt acagaaccaa aaatcaagtt ctacattgca
     8701 gttgtagggg aaaccaacga agaatcacaa gctaagatta ctaacatcga agcagaaatc
     8761 aatgcatttg taaaataaag acctataaaa gatgagacca accaacctca tcttttttcg
     8821 tatcaaatct aagcaatttt agaaacttta tggcatacta gacttatcaa tgaaagcgag
     8881 gtaatctcat ggaacaattt ttagataaca tcaaagacct tgaagtcact acagttgtgc
     8941 gtgcgcaaga agctcttgat aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt
     9001 gcccttactg ccgtaaattt gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc
     9061 acatttactt catcaatagt gaagaaccaa gccaactcaa tgatttgcaa gcattccgct
     9121 cacgttatgg aatcccaact gtaccaggtt ttgttcatat tacagatgga caaatcaacg
     9181 tccgttgcga ctcttcaatg tcagcacaag aaatcaaaga tttcgtagga ttgtaaaaaa
     9241 tcagctaaca agtcttaaaa tcacaaaaac gcataatgta aggtgcaaaa accttgatat
     9301 tatgcgtttt attgttccta aaacagttac atcagtattt cattacagaa cattttaatt
     9361 ttggaagtca aatcaatttt taacaatgtt ttagaaatca cagtgggcta ttccatattc
     9421 aattatccag attcaatcgc tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg
     9481 ctaatcaaaa cgtagtctca gccactattt tatcttactg tccttctttt acttctttgg
     9541 ttgctacatc ttctccaaac catttttggc tgatttcttg gaacttgccg tccttgtaaa
     9601 gactagaaaa agcttcattt atcttcttaa ccaaggttgt atcttcctta cgggctccaa
     9661 ccgcaaaagc ttctgtttct agtccaactg taaagacatt ataatcgttt aaaacacctt
     9721 ctgcttctaa ataatagttt gcatagacac ggtcaatcaa tagaccatca attcgatcgt
     9781 ttttcaaatc aatcaaggct tcattaaagg tttggtattg attcgcttcc ttattagcga
     9841 caatattctt caaaagttct ggatttgctt caaagtccgc ataaccagat gaaccagctt
     9901 gagctcctaa tgtctttcca gtcatatcct ttgcagtcgt gataccagat gatttcttcg
     9961 taaccaatac ctgctcattc ttcatatatg agttactgaa agccaccttt tcacggcgtt
    10021 cgtctgtagc ggaatagcca ttccaaatca gatcaatcgt tccttttgtc aattcagctt
    10081 ctttcaaatc ccaatcaatc ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag
    10141 ctgtagctaa atcaatatca aatcctgcat aagaaccatc tttctgagca aatcccattg
    10201 gaacaaaagt actatcaaat ccaatagtaa tagacttgtt agactggtac tttgaccaat
    10261 tatctccact agtttcgcta gaatttttcc cacaagctac taagaacaaa gcagtcatca
    10321 gactgactaa tacaagcatc cattttttca tccatttttc ctcctattta ggttctactt
    10381 tcaataatac atctgcgata ttttcagcaa actgcaaatc atgggtaacc acaatctggg
    10441 tcatcccaag ttccctattt tgcaagatta gcttctccac ttccaaacgt aattctggat
    10501 ccagggcaga agttggttca tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg
    10561 ccaaagccac tcgctgcttt tgcccaccag atagtgagaa aggataggcc tctgcgtgtc
    10621 ctcctagtcc taactgttcc aagagtccac tcgccttctt ctcagcctct tcctgcttca
    10681 ttcccatggt cttcacaggc gataaagtca aattttccag aactgataga tgaggaaata
    10741 gttgaaaatc ttggaagaca aatcccagta ggttgcgctt ctgcaattca tccagctcta
    10801 aaggttgtcc attataaaag atttgccctg aatcaatggt ttcaagacct gcaagcatac
    10861 gtaaaagagt tgtcttacct ccaccagaag gtccaacgat agccaggatt tgcttttcag
    10921 gaatacttag actgaaatta gacaggattt gtttgtctcc aaagacttta ttgatatttc
    10981 gtaattctaa catggcagcc tcctatctat aataactata cttcttctca acttttttgg
    11041 aaataattgt cacaatccca atcaaaatca aataaatggc tcctgccaag aacataggaa
    11101 ccagactagc atcgcggtta gcagctgttc gactagccaa gataaggtct gaaattccga
    11161 gagcatagac caaagaagta tccttgacca aactcataac ttcattaaag acactaggaa
    11221 gaacgatctt ggtcacttgg ggcaagataa tatagcgcac tctgtcaaaa gggctaaact
    11281 tcaagacctt ggcagcctca tactgtcctc ttggaatagt gtcaattccc ccacggaaaa
    11341 tttctgcaaa gtaagccgca taattcaaaa caaaggcaat aatagctgca ggaaggcggt
    11401 ctaaacgaat cccaatactt gggagcacat aatagataaa aatcagttgc aagagtaagg
    11461 gggttcctcg cataacccag atgtaaatgt taatcagata atggaggggc ttccaatgga
    11521 cttgcaaggc aaaggcaatc aaaacgccca agggaatcga aaatagcaag accagtgcaa
    11581 agacctgtac agtcgtgctc gcaccattca gtaaactcgg taatatctca aataaataag
    11641 acatactgca cctcctaaaa gtaattgttc ctattatagc atgaataaac aagattacca
    11701 agtatttttg taaaaagatt ctaccatata caaataaaaa ccgtagctat caaaagagat
    11761 aaactacagt tctatatgtt taaacattct tacaatctct caaacagttc ttgcatttgc
    11821 acatcatctg gaaccagttt taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt
    11881 cccaattcac gcaagagata gatatagtgt tccagaaatt ctggattgtc cttcaaatct
    11941 cctgtcaact cttgataatg ctcataagca gtatccaaat cgtccatttc ttgataagaa
    12001 cgagcaatca tccacttggt caaaagattt tctggctcct cactctgcaa gtctagaata
    12061 tcctcataac gctcctgctc cagataaata gtggctaaac gaagcaagat ttcttctgta
    12121 tcctcagcgt cttcttttgc agtaaggaga taattttctg caccactagc atcatgcaat
    12181 tcataagaaa attgtgaagc agctagcaag aggcgagttt caaagggatt tttctctaat
    12241 ccttgcttag cgatacgcag ggcttcttga acttgatgtt ccttatgtaa agcctgactg
    12301 tacccatact catagccttc aaagtcagga gaaatggtat caagctgctt aaagtagagg
    12361 gtggcttttt gatattcttc ttgatcaaaa taaagactgg ccaactcaaa agctgttaag
    12421 tcatcgtatt ctaactccag ggctttttct aaaaactcag tagccgtttc aaatttccct
    12481 aactgagcat aggcaaagcc aattcgttga taggtggaaa tgcccgtttg ctcataaatc
    12541 gagcgattat ctaactgggc ataggcttga atagccgctt ggtaattttc caactcacta
    12601 tccaactctg ccaaacccaa tatcaagaga gaatcctctg agtaggtcaa ggcctccaat
    12661 aatttctcac gtgccacatc tgtcaaacct tccagctggt aaaggtctgc cttcagagcc
    12721 aaagacgaga cataccagtc actgtcagct tggatttcct caagataggt aaaggcttct
    12781 tctatttgac catcctcgct agcaattgca gctagattaa gatgaacctc tggaaaatcc
    12841 tctacaattt tcaggtaaat ttccttggcc tgaggataga aaccaatccc ttcaagataa
    12901 gttgccaact catacagaag atcacttgaa tcattttcta aagctttggc gaaataatgc
    12961 tcagccttag ttaaatcttg ctcctccaaa gcctgtaaca tctgttgact attgttcact
    13021 cttgacttcc tcaccctcta attcatatag accactgact accttatacc attcgaaaat
    13081 ggctgaaatg acaaccttag cagaggcata aaccggaata ccaagtaaaa ctccccagat
    13141 accaaacata gatcctgaag ttaacaaaac aaagagaaca ttaataggat ggatgtttaa
    13201 ttgacttccc aaaatcaatg gagagacaaa acggccttca atagtttgtt ctacaataaa
    13261 gacaatcact actttcaaaa gcatgactgg accagcaatc aaacccaata ctagggcagg
    13321 aagcatggct agaaagctac caagataagg gaccagattt aaaataccag cagtaacccc
    13381 cagcgtaacc gcatagcgta gaccaataat cttgaagaag atgataaaca ttactgctac
    13441 aataatagcc actgtcactt gccctcgaac atagttggac aactgttgat tcacatctga
    13501 tagaacttgt ccaacaggtt ccttcaattt tcttggaatg aattgggtca aatagttacg
    13561 caagcctttc ccatcacgca agagataaaa gagcatgaaa ggaacgataa tcaaggcaac
    13621 aatcacttga gaagctccgc taataaaggc actcacccag ttgactgcct gagatgaaac
    13681 cttacttgcc aaaactgtag cctggctaga aaaattggtc aaaacttgct ctaattgagg
    13741 tctgaaatca tctggcaggt gctgggctac caatccatta acaatcctat ctatatcttc
    13801 taagtaaaca ggaacgtttc ttgcaaaggt caaaacctga cgttgcagat ttggaatggc
    13861 gactgccaag ccccaaatga taaagagagc gatgataaca aagacaatag tgatagctat
    13921 aacacgatta accttatgct tctccatcca atcaacaata ggattcaaca aataatataa
    13981 caaaccagac aaaatgactg gcaacatcac aactgctata aagtctaaaa caggtgaaaa
    14041 tagaaaacta atcttactta aaataaaaag attcaatccc aataataagg ttactaaaaa
    14101 taccgtaatt gccttgttat ctaaaaacca cttgaaaaac caagataggc taaaatgttt
    14161 ctctttttgc tccataaata cttcctttct attgttctct cattatacca tttttgaaac
    14221 aaaataactc ttttttaaag tgcttacatc taattgaatg tctttaattt gcttgttttt
    14281 gtgatataat agtcttatct ttacacagag gtatagtaat gaaagaaact gtttattttg
    14341 gaacttatac acgtcgtact tctcaaggga tttacaaggc agactttgat acagaaactg
    14401 gtcagctttc aaatctagaa ctttttgcag ctgagccaag tccaacctac cttgcctttg
    14461 accagcacca acatttatac actgttggta gccaagacga taagggggga attgcagcct
    14521 atcaaactga cgggactgtg ttaaatcatg ttgttgaaga aggagctccc cactgttatg
    14581 ttgctgtcga tgaaaagcgt gatttggttt acgcagccaa ctatcacaag ggacaagtcc
    14641 ttgtttataa acgccaggaa gatggtagtc ttctacttag tgatatggat caacacagtg
    14701 gccaaggtcc acatgaaaat caagcttccc cccatgttca ctatacagat ttaacacctg
    14761 accactatct agtgacctgc gacttgggaa ctgaccaagt catcacctat gacctcgatc
    14821 aagaaggaaa attatctaag ctctatacct atcacagcaa gccaggagca ggctcacgcc
    14881 atatcatttt ccataaccac tataaaatcg cttatctcat ttgtgaactc aatagtacta
    14941 tcgaagtttt aatctacgat ggcgttggcg aatttgaacg tatgcaggtt atttcaactt
    15001 taccagaagc ttacgaaggc tttaatggaa ccgctgctat tcatctctct aaagacggta
    15061 aatacctcta cgcttctaac cgtggccatg attctatcgc agtatatacc atccttgcgg
    15121 acggtagctt agagttatta gaaatcgttc caacgcatgg tcagactcca cgtgattttg
    15181 atttgacacc cgaccaaaaa tttctcattg ttgtccatca agactctgac aatgcaactg
    15241 tctttaaacg taattgtgac aatggtcgtc tagcagaact ctccaacgac ttccatgttc
    15301 ccgaagcagt ctgcatccgt tttgctcctt aaaacaccat aaaaaatgaa cttggtattt
    15361 tcaagttcat tttttcttat agtctatttc cgacattaat acggttaata gcacgttgca
    15421 aagcaatctt agcacgacgt tcttggtcaa tcaaatgttt gtcttgtgct tcttcaattg
    15481 cacgttctgc acgaagtttg gcacgttctg cacgactgat atcgatatca cgagcacgtt
    15541 ctgcagagtc agcgacgatt gtgatcatat cattggcaat ttcaataacg ccaccgttta
    15601 ctgcaatcca gttcacgtga tctttatcat cgatacgttt tacctttact tcatcaactg
    15661 ctaaaaccgc aatcatattt tcatgtcgtg gcaagatccc catctcacca tccagagttc
    15721 gaaccgatac atagctggca tggtgatcat agacgagacc atctggtgtc acgatctgga
    15781 cagttaactg agccatagat cacctcttaa aatcccattt tttcagcttt tgcaatcaca
    15841 tcttcgatag aacctacacc acggaaggca tcttctggca agtggtcgta tttaccatca
    15901 aggatttcct taaagccacg tacagtttca gcaactggaa cataagaacc tggctgacca
    15961 gtaaattgtt ccgcaacgtt gaagttttgt gacaagaaga actggatacg acgggcgcga
    16021 gcaaccaagg tcttttcttc atcagaaagc tcatccatac caaggatagc aatgatatct
    16081 tgcaattcat ggtaacgttg aaggacacgt tttacttcag cagcaactgc atagtgctct
    16141 tctccaacga tttcaggtgc caaggcacgt gagcttgaag caagtgggtc aacggctggg
    16201 tagataccca attgtaccaa cttacgttcc aagtttgttg ttgaatccaa gtgagcgaag
    16261 gctgttgctg gcgctgggtc agtatagtca tccgctggca catagatagc ctggatagag
    16321 gttacagaac ccttcttggt tgatgtgata cgttcttgca attgacccat ttccgtagca
    16381 agtgttggtt ggtaaccaac ggctgatggc atacgaccca aaagggcaga tacttctgaa
    16441 ccagcctgag tgaaacggaa gatattatcg ataaagagaa gcacgtcttg gccttccaca
    16501 tcacggaagt attcagcgat tgtcaaacca gtaagggcaa cacgcatacg tgctcctggt
    16561 ggctcattca tctgaccaaa gaccatggct gttttctcga taacgcctga ttctttcatt
    16621 tcccagtaaa ggtcattccc ctcacgagta cgttccccaa caccagtaaa tactgaaata
    16681 ccaccgtgct cttgggcaat gttgtgaatc aattcttgga ttaagacggt tttaccaact
    16741 ccggcaccac cgaaaagtcc aactttacca cctttaaggt aaggggcaag aaggtcaata
    16801 accttgatcc ctgtttcaag gatttcagaa gaggtagaca actcatcaaa agttggagct
    16861 tttttatgaa ttggctgacg ctctgcgtct tctgtaaaag gagcttccaa atcaatggta
    16921 tctcccaaaa cgttgaagac acgtcccaaa gtttctttac ctactggtac agagattgga
    16981 cgacctgtgt ccaatacttc cattccacga gtcaacccat ctgttgattc catggcgata
    17041 gtacgaacca taccatctcc taactccaag gctacttcaa ggacgatttt tgtttttctt
    17101 tcgtcatttt tgtagacgac aagtgcattg ttaatctcag gaagtttttc ccctgctgca
    17161 aacaaaacgt ctacaacggg accgataacc tgagcaattt tacctgaact catctccttc
    17221 tcctattcta tataagatac tgtcggttcc tagctcaact aggtcctaag ttcattttca
    17281 tacgagctgg actagagcct attctaaggc actagcacct gctacgattt ctgtaatttc
    17341 ttgtgtaatc gccgcctgtc tggcacggtt atactgaatt gtcaaatcat tgatgacttt
    17401 cttagcatta tctgtcgctg tttgcatggc tgtcataccc gcagcattct cagctgtctt
    17461 ggcatcgata atggcaccgt aaatcatact ttctgcaaac tgaggcaaca actgctccag
    17521 aatttcttct cggctggttt ccaattcaaa agtcaagctg tactcttcat ccgcttcatt
    17581 tggatccaag tcaacaatcg gaagcatttg ttccacacgc atttgactgg ttagcgtatt
    17641 gacatggtgg ttgtagcaaa cataaagctc atcaaagagt tcattttggt acatttcaac
    17701 agtttttgaa ataatcttac gaacttgatc aaagctaggt tggtctgcca agccacgtaa
    17761 ttcataaagt ggttgaatac cgcgagcctt aaagaaatca gctcccatcc caccgataca
    17821 gatcatttca aaacctttac cgtctgggtg gtattcttct ttcaactcca taacagcttt
    17881 caaaatagag gaattataac ctccaaccaa accgcggtct gaagtgataa cgatatagcc
    17941 tgtcttcttc acagaacggc taatcaacat cggattagtt gaagcaccag ctccattacc
    18001 atgaaggata tctgtcaaaa gtttacgcac tttctgagcg taaacttgga agttgcgagc
    18061 agcttcttca gagcgaccta acttagcagc cgataccatt tgcatggcat tagtgatttg
    18121 actcgtattt tttgttgagg cgatttttgt tttaatatca tttagagaca ctgccatctg
    18181 acacctctat tcttattgga agctagattg attgagaaac tctgtaatcg cagcatccaa
    18241 gactgcttct tctggcaagt cttttgtatc acgaatggtt tccaaaatct ctggatgttg
    18301 agcatcaaag aaggcatgga actcttcctc gaaacgaaca atatcatcta ctggaacagt
    18361 atccaagaaa ccatgtgtca aagcataaag aatggttact tgtttctcaa caggtaatgg
    18421 tttgtgaaca ggttgtttca agacctcaac ggtacgacgt ccacggttca acttagcctg
    18481 tgttgctgcg tccaagtcag aaccaaactt agtaaaggct tccaactcac ggtatgaagc
    18541 aaggtcgata cgaagtgtac cagcaacctt cttcatggct ttgatttgtg cagaaccacc
    18601 tacacgagat acagatgaac ccgcatcgat ggctggacga atacctgcat tgaagaggcc
    18661 atcgccaagg aagatttgtc catcagtgat agaaatcacg ttggttgcga tataggctga
    18721 gatatctcct gcttgtgtct cgataaatgg tagggctgta attgatccac caccaagttc
    18781 atcagaaact ttagctgagc gctcaagcaa acggctgtgg agatagaaaa catcccctgg
    18841 gaaggcttca cgacctggag gacgacgaag caagagcgat agttcacgat aagctaccgc
    18901 ttgttttgat agatcatcgt atacaatcaa aacatgctta ccttgataca taaattcttc
    18961 cgccatagca accccagtat aaggagctag gaagagcaat ggagatggtt gtgaagcaga
    19021 ggctgtcaca acgattgtgt agtccaaggc accgtactga cgaagtgttt ctacttgcgt
    19081 acgaactgtt gattcttttt gtccaatcgc gacgtagata cagatcatat cttgatcttt
    19141 ttggttcaag attgtatcaa tcgcaatggt tgttttccct gtctgacggt caccgataat
    19201 caactcacgt tgaccacgac caatcggtac aagggcgtca atagctttca aaccagtttg
    19261 caatggttct gaaacagact tacgttgcat aacaccagga gctggtgctt ctactggacg
    19321 agttttatca gtgtggattt ctccaagacc gtcaactgga cgaccaagcg gatccacaac
    19381 acgaccaatc agactttcac ctacagggac ttccatgatt ttccctgtac ggcggattgt
    19441 atcgccttca cggatatctg taaagtcacc taggatgata ataccaacgt ctgttgactc
    19501 caagttttga gccataccat aagagccgtt ttcaaaattc aacaactctc cactcatgac
    19561 attttcaagg ccatgagcac gcgcgatacc gtccccgata taggttacaa cacctgtttc
    19621 agtcacatca aaattgggtt tgaaattttc aatttgttgc ttaattaaag cgctgatttc
    19681 ttgtgcgtta attgccaaaa gaacaccact ttctatttca aattttcttt aacaacttta
    19741 agttgttgtt taatactcac atcaattgtc ttgtgattgg caaaaatgac aaaaccacca
    19801 atgagacttt catcgatttg ttcttttaca ctccttactt tcagagacat ttttttctca
    19861 atcaaaggga gcaaacgagt cttctgttca tcagttagag gatgagcaga cgtaatcgtc
    19921 acttcaaatc gatttgtttc tttttcaagt cggttcaagc aatctacaag cacatcataa
    19981 aaaagatttg ctctgtgatt gtaggccaga acctggataa agttttgtaa taaaggcgac
    20041 acagaatctt ggaaaaaagc aattgttttt tccttatccg actcgtctac tgccacttgt
    20101 tttaaaaaag aaggcagacc tgttttttca acaacttgct tgatttgagt caagtctgaa
    20161 aagatacggt cttcttctcc tttttcaagt accaattgga caaaaggcat gctgtatttt
    20221 tcaattacct ttactgtttt cttgtccatt aagcttctcc tagctgatcg atatactgat
    20281 caatgagtgc tttatgggca tgactgtcaa ggttttgtga gatgatttta ccagctaagc
    20341 tgatggtcaa atctgcgacc tcacccttaa cactctgtaa agcttctact ttattttgag
    20401 caatttcttg attggctttt tcttttaagt gtcctgcttc tagtttagca tctgctaaga
    20461 tattagcctt actttgctca gctgtttcct ttgcattttc aatgattgtc ttagcttctt
    20521 tacggctacc agccaattca tcttcgcgtt tttgagccaa tacttctgct ttttgacggg
    20581 cttcttcagc tctatcaata tctgaagcaa ttttttcagc tctttcttcg aaaatgcctg
    20641 taatattaga ccatgcaaat tttttaatca agactagcaa aagaataaaa gagccagtga
    20701 ttaaaataaa attaccaatt aattcaccta ctgttacgtg catcagttac tcctttctat
    20761 tcctcttcaa tattaatctt attccctaaa tacacagatg tcaaaagagt aaaaacataa
    20821 gcttggatgc aggaaataaa gacagaaaat gcagtccaag ccaaattagc tccaaaggct
    20881 actggatacc aataaatagc ttggtgggaa agaagaagta acaaactcgt catgacctct
    20941 cctgcaaaga tattcccaaa aatccgcaaa gccaaagata agaagtttgt aaattcttcc
    21001 aagatattca tcggtatgac aaaaacagga ctcataaaag attttatact ttttttaaat
    21061 ccacgacgac gaacgctttc tatatgtgtc aacaaaatga caagaaaaga taaggttaag
    21121 tcatactgta aattagcggt tggcgaactc caccagttag tcccatcgat cgtttgaagc
    21181 tttgtcatta agccaaggtt attggcaatc accatgaaaa ggaataaaca aaggaaaaag
    21241 agtgagtaat ctttcatgta gcgcgaacca atgttaggtt ctgtaaatcc aataacaaag
    21301 tcatagacat actcaagtat attttgcttt cctttgggtt tcaaggtcat attgcggctt
    21361 gcccaataaa taaagacaaa aataactccc acaatcaaca aagtcatggc taacatagtc
    21421 agattgaaga taacaggacc aatagagatg attggattaa tactttcttc catctaaaat
    21481 cctccctttt cttctcgttc catgtattta tttgataata aatgagaaga caagagttac
    21541 aaagaaagtt ccttcaataa aggcaacacc taaaaacatc aaactacgaa actcagaaag
    21601 catatctggt tggcgtgcta ctgatttaaa cagtccattc atcaataaac cttcaccgac
    21661 agatacgccc atacaggcaa tacataagcc taaaaatgtt aaattcataa caaattctcc
    21721 tttaaaataa aatttactta cttagtgtag tcctaaaatt taaatttgtc aacttttaac
    21781 cgctattgga agcgtttaat aaaaattatt tccattttgc taaatttcaa gttcaagtta
    21841 gccatccaga agtcttctct gggtgacttg tagtccaagc attttttagg atagttgtta
    21901 atccactttt cgatgaatgc gacttctttg ggagtcattt tcttggttcc cttaggtaac
    21961 tatctacgaa tgagcctgtt gtgattctca ttagttcccc tttcccaaga ggcatagggg
    22021 tgcgcataat agatgtgctc ctcagaaaat atatcaaaca agcgattgaa ttccgttcca
    22081 ttatctgccg tgatggaaag aatcttgtgt tgttttaaga tgagttttag agcctgattg
    22141 accacctcag cacttttatt tggaatcaat cggatgatct gatgtctact ctttcgatcc
    22201 gtcaagacaa gcaagcagta gtttttcgct ctcgtaagta gaaccgtatc aatctcataa
    22261 tgcccattct ccaagcgaag attgatagct tcaggccgct gtgcgatgga ttgaccagca
    22321 ggtttaaagt tgatgctagc ctgtttctta agcgcttttc cttttctagg gtaaagcaga
    22381 tcctgtttgc ttaaccccaa ttttccatga tgaatccaat agtaaatggt tgaaattccc
    22441 acgttaaccc ctttagccat caccatcatt tcaggcgaaa atttttggtt atgatagtgg
    22501 agaatctttt cctttagttc cttggtcacg cttaatttcc tgaccgagcg cttgcgattg
    22561 ttttcataag actgttgagc atagtcggca gaataaacct ctttgaagcg cccttttcca
    22621 agacattgtc ggactgtccc acgcttgatt tcagtgtgga tagtttgagg aacttttcca
    22681 agcagagagg caatttctct atttgatttt ccttcttttt tccatcgttc gattaagcga
    22741 cggctatcga ttgtcaaatg tttacctttt gtagtataat ggttttgcat ctctgtgcct
    22801 ttcttgtgtt tgtggttgaa caacaagtat aacacagagg tgttttctta tgcctacaag
    22861 agctttcatt atttccattt tcttttggat ttcactctat tctgaaaaac ttgtgtatat
    22921 ttactgaagc tagcaaggct tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg
    22981 ggaatctcgg attaatgtca atttaaaaag atagagagtt tttagtttaa ataaattgtt
    23041 ttaaaatatc aacaacatca cttcttttct taacctgata agccttgatt cctaattttg
    23101 gggctacgat tatattgtcc tcaatatcgt ctagaaagac acaatttcta ggttataact
    23161 ggtatttatc gatagttact catatacatc agtccacctc catactcgcc ttacagattc
    23221 ttttggtaat aatatctttg cctaatgtag agatagtctt gcaaagaaaa aacttccttg
    23281 tagccatgtt tctgataaaa gtccagtgcc tggaactggt aagtattgac aaaggcaaaa
    23341 caacaatttc gattcttagc ttcactttct gcctgttgca atagttttga accgattcct
    23401 tgccctcgca gttcctcttt tacaaacaaa tactcgattt ctagccaatt tccaaaagtc
    23461 tctgctatca aacccgcaag gagattgccc ttttcatctt cgacataaag attaagtggc
    23521 tcactttcag cctcttctct ttttgaacgg ttataaacac gaatcagatt ccctatttct
    23581 tgcgatttat gtgattcctt attttccaat ctaaggtata atgaaatgaa ataaaacatg
    23641 cgcaaatcga ttaaggaatt taatctaatt tctaacaatg tcttagaaat caaagtgtac
    23701 tattttaact tcaatgcatt atacatctaa tactcaatga aaatcaaaga gcaaactagg
    23761 aaactgacga agtcagtaac catacatacg gcaaggcgac gctgacgtgg tttgaagaga
    23821 ttttcgaaga gtagcaaaat ggaaaaagga gtgagtgaag cacatcgcct ccccactcct
    23881 ttttctgttt ttaggctgtt ttttcaacct tcaagatttt tacatcatag ctaccaacag
    23941 gcgtttcaat ggttgctgta tcacctgttt tcttgccaat caaggcctgc ccaattgggc
    24001 tttcatttga aaccttacct gcaaaggcat ccgcaccagc tgaacctacg ataatataaa
    24061 cttcttcttc gtcctcacca atttcttgga tggtgactgt tttaccaatc gctacttcgt
    24121 cctgggcaac tgcgtcgcta ttgacgattt cagcatagcg gatttttgtt tctaagctag
    24181 agatttgtcc ttcgacaaag gcttgttcat ccttagctgc ttcgtactca ctgttttctg
    24241 aaaggtcacc gtatgaacgg gcaatcttaa tgcgttctac cacttctggt cgacgaacca
    24301 atttcaattc ttctaattct ttttcaagtt tttccttttc ctcaagggtc ataggatatg
    24361 ttttttctgc catttttctc aactttcttc tgataatatt ttctaaagaa aattatgtga
    24421 agtatcacat aattttagtt tgtttagttt aatttgctgt tgacatgttc agcgacattg
    24481 cggtcgtggt cttcttgatt gttagcatag tagaccttgc cttctgtgac atctgctaca
    24541 aagtagaggt tatcgctctt agtttgattg atgcttgact caatcgcatc cagacttgga
    24601 ctatcgactg gaccaggcat gagacctaca tttttataaa cattataagg tgaatcaatg
    24661 ttggtatcaa tcgcaacatc ctcagctaga ctgatatttt gccccagttt tccttgggca
    24721 tacaagattg caatattact ttgaagtggc atatcacgat tcaaacgatt gtagaataca
    24781 cctgcaatga gcttacgatc ttctgtcttg gcaccttctt tttcgaccaa ggaagcaatg
    24841 gtcaacaact cattgacagt caaattttta gatttgatag tactatagta aggagatagg
    24901 ttcttatcca tagcagctaa catctcatca atcaagctct caatagttgt gctttccttg
    24961 atagagtatg tagctgggaa aaggtatcct tccaaacgat aacgcgcacc gctgtctttt
    25021 acaggcaaac tttccagtaa agtaggatat ttcgctactg cttgactgat aaacgtctca
    25081 tcttgaactt tagccaagaa agcctccgct gtcaaagact ctttgaagtc accttgcaat
    25141 tgacccacag cttgagcaat ctgatccaag gtataacctt ctggaattgt caaagtcgca
    25201 agtacaggtt cttgcggttc atctgttcca cctttttgca actctttgag taagtcttct
    25261 gtactcatac tcttttgcaa attgtagtaa cctgctttca agtcggtata atttttatac
    25321 ttggcataaa aactaaaaat cagaccatgc tttaccaaac cagctttttc aagcgtcgta
    25381 ccgatttctt gaacgtttga accttctgga attccaaccg tcacatattt cttagaatta
    25441 gcatcgatag gtaacaaaga atctagcacg tactggtaac caaagtaacc acctgctgag
    25501 agcaaggcaa ggaatacaag gaatgaaatc acaaaagctt tcacatgtga cttcttctct
    25561 ttcttaggct taacgggttt tgctccttct ctacggctac gacgtgatgt atcgctgatg
    25621 atatccactg tttctgtagc aggcgtaggt gtttctgaac ctgcttgttc tgcttttttc
    25681 tctgccgtcg tataggaaac agctaccctt gttggggttt cattgtattc tctttcaagt
    25741 ttcttaggtc taacaggacc tggacctggt cttgatccac tttcttccgc tggagaagaa
    25801 ggtacatctt gacttggatg acttggaaca ccaggagttt ctctttgaat ctcatctgct
    25861 ggagaagctg gtacaccttg acttgggtga gtaggcacgg taggagcttt tctcataatc
    25921 tcctctaccg ttgacaagga atcagccatg agttcttcag ctgaaggttc atttgcagga
    25981 gtgcgaacta ctgcctcatc ttctttcaga acttcatcat agccttttac tttttctaaa
    26041 tctctcagaa tctgctcttt aaagcttaat ttctcttctt ctcttgactt ttcactcaaa
    26101 agtttttcct ccttgttgat aatccataat attatatctt aaaagtccaa aaaaagcaat
    26161 ctatgatact tttcctaact tattttttca tttcccagac catatcatac catgtttccc
    26221 ctgcaaaggt tgactgggac tggccttcgt tgacaaatcc atgtttttca taataggcga
    26281 tgagatagtc atgacaggtt agattaatgc catctctctc atcttcaaga gcaacttctt
    26341 tcaaggctgt cagcaatttc tgacccagtc cgagtccctg tgcctccttg gcaatagaca
    26401 gacaggtcac agagatataa ccaccaggct catgactata gtcttttatt tcttctgtaa
    26461 aagactggtc ttgcagatgg cggtgcaggc caactggtcc ttcgatataa cccatgattc
    26521 ttccttcttt ttcagcaacc agaaaagagg tctgaatttc tctcaaatgt gcttcaaaga
    26581 cagaaggagg aatggcttct tcgaccgaaa aattttcaaa ttcaagttca acaatccgat
    26641 ccaaatcttc taatcttgct tgtctgattt tcattgttcc tccagataaa agggattaaa
    26701 ccaaatcata ctatagccct ggctagttgc atagagcaaa gttgcttctt catcaacaaa
    26761 accgttcatt tcaaaatagg aaagcagctc atcaggactc tccaaacgaa tccctttgta
    26821 atccagctca actgccacct ctttcaaggc tgcaagaaga agtgttccca agccctgtct
    26881 ctgatggtca gactcgatga ctaaagaatg tacttttaga tattgcggat tgtctgactg
    26941 gggacttgat aaaatatagc ctaaaagttg attttcatcc ctagctagaa gaaaggtatc
    27001 cgcacactta cggatacttt cttctaaaat atgggaaagt tgctgctttt cagctggaaa
    27061 agacgaggtc tgaagtgccc ctatctcagg caaatcagac ttgcttgcct gaatgatctt
    27121 aattggaatt tccatgggaa catcctattg aacattgctt gtcaagttag acaagagacg
    27181 ctcaaatgag tattcatagg tttggatgtc tcctgctccc ataaagacgt aaacagcatt
    27241 gtcatggtct aggagcggag aaacattttc aacagtaatc acttggtgtt ttttgttgat
    27301 tttgttggct agatcttcta ccttaacgtc accatgatct acttcacgag ccgagccata
    27361 aatttgcgct agataaacag catctgcttg gtttaaagca tgggcaaagt cgtccaacaa
    27421 ggcaatggtt cttgtaaagg tatgcggttg aaagactgct acaatttcct tgcttgggta
    27481 tttctgacga gccgcatcca aggtcgcaat aatttctgtt ggatggtggg caaagtcatc
    27541 gataatcact gtatcattga caattttctc agtgaaacga cgtttaacac cagcaaatgt
    27601 tttcaagtgc tcacgcacca agttcaaatc aaatcctgct gtgtaaagaa gaccaataac
    27661 ggctgtcgca ttcatgatat tgtgacgacc aaaggttgga atgtggaatt gccccaagtt
    27721 ttgtccacgg aaatgaacgg tgaaggttga accagttatt gaacgaagaa gatcactagc
    27781 tacaaagtca ttgccttcaa cttcaaaacc ataataataa attggtgcat cagacgtaat
    27841 cttacgcaat tcagcatctt caccatagac aaaaagaccc ttggtgattt gtttggcata
    27901 gtcgttaaag gcattaaaaa catcctcgag acttgtgaaa taatctggat ggtcaaagtc
    27961 aatgttggtg ataatagagt attctgggtg gtaaggcatg aagtgacgct catattcgtc
    28021 agattcaaag acaaaatatt tggcattggc cgaaccacga cctgtcccat ctccaatcaa
    28081 gaagctggta tctgtaatgt gagacaagac atgagacaac atacctgtcg ttgaagtttt
    28141 tccatgtgct cctgctactc ccatgctaac aaagtcacgc ataaagctac ctagaaactc
    28201 atggtaacgt ttgtagctga taccattttg gtccgcatag gcaatttcga cgttgttatc
    28261 tggacgaaag gcatttccag cgataatttc catatcaccg tctagattct tttcatcaaa
    28321 aggaagaatg gtaattcctg cctgctcaag accgcgttgg gtaaagtagt acttttcaac
    28381 atctgatccc tgaaccttgt gccccatctg gtgcaacatc aaggccaagg cactcatccc
    28441 tgatccctta attccgataa aatgatatgt ctttgacatg ttttctcccc tattctgtca
    28501 ttctggtcag attcaactct tgggcaaccc gacgttcttg ttctgtttgt ttactttttt
    28561 tattgtagat ttggctcttc tttagaaaat cataattgtt tttctttgga gcaggtgctg
    28621 acacttcttc attcttggta gggatagaat gaacttcttc cgccaagata taatgagact
    28681 gggtcaattt ttggctatat ttgacaaatt caccaggatt ttccttttgg aaaggagttg
    28741 tcggttgatt gccctgtcta actagactgg gctgagaatg acgtctcgca aggctgaaat
    28801 cctgagttag atagttagca gagcgtttct ttttcaagtc tgcacgcgct tcttcacgcg
    28861 ccacctccgc atagctcttt ccttcttttt taacccctaa aggagctttt ttaggtttcc
    28921 ctacttgctt ttcaatcggt tgtactggtt tttcttcagc aataggagcc cattctaaat
    28981 aatttttatc tcgatactca cccttgatat tactgatcag atcagactca tcatagagat
    29041 tcatgactgg catttcagtc aacatgacct cgtcatctga caccaatgga aatcgttctt
    29101 gtttcatttt ctatttcctt tcaacacttc attatagcgt attgtcttga tttttcaagt
    29161 gctggcttca gaaattccca aaatttctct aatttctgct agggtcagac taccacgtga
    29221 ctctgtgccg tccaatactt gtgacaccag atgtttcttt tgttcttgga gttcctgaat
    29281 tttttcttca atggttccct tggtcaccaa gcgatagacc tcaaccgttt cttcctgacc
    29341 catccgatgg gcacggccaa tggcttgcgc ttccaccgca ggattccacc aaaggtcaac
    29401 caagatcact gtatctgcac ctgtcaggtt cagaccgacc ccaccagcct tgagggaaat
    29461 cagaaaggca tctctttctc cttgattaaa ggccttggtc atgtcttgtc tttccttggc
    29521 tggggttgaa cccgtaattt taaaggaagt caggcccaag tctggcagtt cttgttcaat
    29581 tttttccaac attcccttga actgagagaa aatcaagaca cggtgtccgc cgtctgccac
    29641 ctgtaccagt aggtctcgga gactatctag tttgccgctg gctccctgat aatcttccat
    29701 aaacagggca ggagtgtcac atatttgacg caagcgcatc aaaccagata aaatttccac
    29761 acgacttcgc tgaaattcct gttctgacac ttgagccaga tggtctcgca tctgttgtaa
    29821 ctgggcaagg taaatagcct tttgctggtc ttccagttca tttttataaa ccacctcaat
    29881 caagtctggc aattcagtca gaacttcttc tttcttgcgt cgcatcacga aaggcttgat
    29941 aaactgagcc actcgctctg ctggcaattt cataaattct ttcttgcttg gcaaaagtcc
    30001 gggcatgacg atttggaaaa tagaccacaa ctcacccaga tggttttcaa tcggagttcc
    30061 tgacaaggca aagaccgacg gcaccacaaa ttgtctcaag gtctgggcaa tcttggtctg
    30121 ggcatttttc atgacctgag cctcatctaa gaaaaggaag tcaaaggcca tcccctgata
    30181 aaactcactg tcctgacgga aggtggcata gctagtcaca tagatttgat ggctctcggc
    30241 aagaatctcc tcacgacttg ctttcaaacc atgaacaaca accacatcca actgtggggc
    30301 aaatttctga aactcatctg cccagttgta aatcaaacct gacggagcga gaatcaagac
    30361 tcgactttct tttgtcactt gactagtcaa aaaagcaatg gtctgaaggg ttttcccaag
    30421 tcccatatca tcagccaaaa tcccaccaaa accataatga tggagcatct gcaaccagcc
    30481 aattcccttt tcctgataat ctcgcaagtc agccttgacc tgagttgctt gcaaaggaaa
    30541 gtcctctgga tgcgtcaaat cctgggccag attctggaat tcttgtgaaa aagaaacacg
    30601 gtctcgccct tcaaagagat gagctaaact gtaggccaag gatttccgag cctgcaaggt
    30661 tccatctttt aattcaaatt gccccagttc ctggagattt tggcgaattt tcttggtttc
    30721 ttcatcgaaa aagtaaactt gattagacga atcaatataa aaatcctgat tggcaaccaa
    30781 ggcctgcatg gcttggtcga tttcctcctg ggcaatattt tgaaaatcaa actggatttc
    30841 caagagacct cccttggagg caatctgcac ctgaggactc gctaggctat aaagctcttc
    30901 tagtttatct gataggtcaa catgcccgag tttttcaaag actggaatga tatcatgaaa
    30961 aaaatgatag acagactccg cttttaaggc ctgacgccaa gattgaaaat cggcttcaaa
    31021 gcccgcagcc aaacagactt ggaaaattct ttcttctaag tccgcgtcac ttgaaaaggg
    31081 taattcttct agctcttgtc ggctagatac ctgtctattt ccataatcaa actgaatttc
    31141 taaacgaatc cgattatctt cttccctgtc aaagtaaaaa gagggcgcaa aagttttgat
    31201 ttgtagacgt tctggagctg aaacggtgcc catctggata aaaagagtca gacaggaggc
    31261 caatttgtct cgatcactgc tatcaaattg caggtatttc tttccttgtt gacccacagg
    31321 taacgcttta atttccttga gaagacgcat ctgctggtct gttaaaaaat aaacctgacc
    31381 tttatggaaa agtactgctc cttgataaaa gacattgacc ctaggactct cactgatttc
    31441 catttcaaaa tagtccgagt attctgttac tgtaaaggca aatagattgg catcagcatg
    31501 catatcctga aaaagcaggg tttggtagct atccacttga tggtcaaatt gaaaatgggg
    31561 caaggccatc agtaaattca caccctgctc aaaaaaggtc agagggaaaa agaggtgccg
    31621 accttggttt tggaaaaaga ggtctggaac cagcccttcc tccgttagtc cgtgcaagaa
    31681 agtcaaaagt tcttggctgg catcatcaaa ggcttcccaa gaaagagact cctcataaat
    31741 cttgccaatc atatacgact ttctctgctc gacaatcctt aaaaaaagtg gaatatcccg
    31801 aatgacatag tatttttggc tattgatttg gccgattctc agagtccaca agatatgatt
    31861 ggttcctgct tccacctgac ccacagctga taactcatag gcgcattctg attttggaga
    31921 taaaattcga ttcaaaaact tgccacccaa ggtcaccttg gtttcaacgg cctctttttc
    31981 ttcatgacct tcttccagac tccacaagat ttcctgacca cgctcatcat ttttcagaaa
    32041 atgctctagc gctgccaaat gcacacagta gcccctcttt tgaaaagaat cacaggcaca
    32101 aaaaaccaaa tcatcctcta aactatagcg cagttcttct tctgcaacgc gagcgtagag
    32161 ccgattgttc ttttccttga tgatatcaac cttaccagtt tcataaaggg caacaccttc
    32221 gatacgaact ttccccggaa tcaatttagc catattttca cctttacctt atctttttat
    32281 tataccatat tttcgcctat gaaaatagcc ttctaggaag acttttctcc tagaagactg
    32341 gatttttaac gtttggcaaa agtaaccaca atccgctgac agacttcctg caacagagat
    32401 ttgggcatag ctatattgat gcgggcatgg agacttcctt cctctccaaa atccaaacca
    32461 cggttgagga taaccttggc ttcatttctc aacaactctt gcaatgtttc atcagtcaga
    32521 tcataggctg aaaagtcaag ccaaatcaag taggtacctt gcggtttcat gaccttgatt
    32581 ttagtctctt ttccaaatag atctaccaca taattgatgt ggtcttcaaa gacttgcttg
    32641 agttcctcta gccaatcttt accgtatcga taggcagctt ctgtcgccaa ataacccaag
    32701 cctgaaattt catgctgatt attggccaac aggcgtttct ggaaagccag tctcaactta
    32761 ggattttcaa tgactgcata ggaatttttt gttccagcaa tattaaatgt tttagtggca
    32821 ctgctcaaga cgatagcaaa atttttgaag gcaggattga tggtattgaa agactggtgt
    32881 ttgtgaccaa agagggtcaa atcttggtga atctcatccg aaactaacaa aacaccgtgt
    32941 ttttggcaga gttggccaat cttctccaac acttcttttt cccaaacacg tccaccagga
    33001 ttgtgaggat tgcaaagaat atagagttta acctcctctt ccaccaaatc cttttcaagt
    33061 tggtcaaagt caatctcaaa cagaccatcc ttttccacta aggaattagt aatcaatcta
    33121 cgattattca acttgacact gcgagcaaag ggtgggtaga caggcgtgtt aattaaaacc
    33181 gcctcgcctt cttttgtaaa ggtttgaata gctgttgaga tggctggtac cacaccctcg
    33241 ataaagacaa gagcctcttt gtcaaagttg taaccgtatt gtgtagcttc ccacttttga
    33301 acttccttaa ttaagtcttc actggcatag gtataaccat aaaccagttg gtctgcgtaa
    33361 gtttgcacgg cttggcggat ttcaggcaag accacaaagt ccatatccgc tatccaagct
    33421 ggtagaactt cactatccgt ttctgtttct ttccatttat aggtatggtg ccctaaacgg
    33481 ttgggcaggc ttgtaaaatc atattttccc atctttgtct tatccttcta aggcttggcg
    33541 caaatctgca atcaaatctc tagtatcctc aatcccaata gacaaacgca agaggtcatc
    33601 tgtcaaacca taagaatggc gtacttctgc tggaatatca gcatgagttt gagtcgttgg
    33661 ataagtaata agactttcca ctccgcccaa actttccgca aaagagaaga ccttgagact
    33721 gttcaaaata tgaggaatgc gtgtttcatc ggctacttta aaggaaatca tgcctccacg
    33781 accagtgtag agaacttcct taactgctgg agaatccttc aaaaaggcaa ccacttcttg
    33841 ggcgttagct gttgagcgct ccatacgaag agacaaggtc ttgagaccac gaagcaactg
    33901 gtagctgtca aatggagaca agactgcccc tgttgtattg agattgtaaa aaagcttctc
    33961 gtatagttct aaactattgg tcacaaccac tccagccaag acatcattgt ggcctgctag
    34021 atacttggtt gctgaatgga gaacgatatc tgctccatct tcaatcggac gttggtagat
    34081 agggctatag aaggtattgt ccaccaccac tttggcaccc ttagcatgag ccaattttgc
    34141 tagtttttcg atatcaaatt ccaacatcaa gggattggtt ggggtttcga tatagagaac
    34201 atccacatcc ttttctaact cagcaatcaa ctcttcttct gtattggcat aggtaaaatg
    34261 gaaacgacct tcctgctcca cttggttaaa ccagcgaaaa gaaccaccgt aaagatcacg
    34321 cactgccaag accttacttc ctactggaaa gccgctaaag gccagtacaa tagctgacat
    34381 ccctgagcta gtcgctaggg catagtctgc tgactcaata gccgccaaga cttcctcagc
    34441 cttactacga gttggatttt tagtgcgcgt atagtcaaac ccagtagatc gaccaaactc
    34501 tggatgctga taggtcgttg aaaaatgaag cggtgtcacc aatgcacctg tcgcttcatc
    34561 tgacttaata cccgcctgag ccaaaattgt gttaatgtgt aattccttgc tcatacaata
    34621 cctccaaatc tatagtaact attgtaccac ttattttcat caactcattt tcttcttttc
    34681 aagagctagt tatagtttca aactatataa aaagggagtt tttcctgctc cctttaatag
    34741 actataaaat ggtgaatctc aaaagacacc ttcactctat catttgctcc tgcacaaaac
    34801 gagcataacg ctcatgattt tccagtagtt ccttatgagt tcctgagcca gtgattttcc
    34861 ccccctctaa gaagaaaata caatccacat cttttaccgt tgacaaacga tgcgctataa
    34921 tcacaaccgt cttctccttt aatgcagaat agaggatact gataatcgca tactcagaat
    34981 ccgcatcaag attagcagtg gattcatcaa atataagaat ttcagcatct tttaagtagg
    35041 ttctagctat ttgaagtctt tggctttgcc cccctgacaa gaatcgtccg cgttcaccaa
    35101 cttcagtatc tagtccctct ttcatggagc gaatctcatc acctagtgat actaagtcta
    35161 gcactttcat caattcatca tcagttacta agcgattcaa accgagacaa agattgtcac
    35221 gaatactgcc agataagact gcattatttt gtgaaaccca agcgatttta cttctccatt
    35281 cttttaagtt aaaatcatat atacttgatt gctccattag aatatatcct gaaagcggtt
    35341 tataaaaccg ctctaacaaa cgcacaatcg ttgattttcc tgatccagat ggtccaacaa
    35401 aagcaatttt ttgccccttg aaaattgaac aagtaatatc ctttaagaca ggtcgatttt
    35461 catcataacc aaaatagaca tggttaaaat tcaacccttg tcctgatacc gattttcctc
    35521 actcaaattt ttctttagga actgcaagca agttctccag tgcaactgaa gatcccttgc
    35581 tcctagaata aatagttaca aaattagcta tattactaat aggattaagt aattgaaaga
    35641 ggtaaatcaa aaacgaaacc aaggttccca cagatatata tcctgcgctg acccgataac
    35701 ccccataggt tagcatcaca actatagtcg caaagataaa taagagagca aacggggtct
    35761 caaaagaagt aaccctatct gatttcagtg aattgttttg taccctttca atacaattat
    35821 ccaaaacatc ctgtacactt ttctctgctt ggttagtctt aattaattca tgttcttgaa
    35881 tcttttcagt caattgccct gttaaaaatc cgatttcctc ctgtaaacga cgactatact
    35941 tttcactgat attggaaagg ggcaagataa taaacatcat acaaggaaga gtgatgaata
    36001 aaagtagaga aagattccaa tcaagactaa ataagactac aatggaacca agtaccataa
    36061 ctaaactcag aataatattt gggaaagtcg taattaaaaa ctcacgaatg acactcgtgt
    36121 cattgacaat ggcagaagtc aactccccac tttggctctt atcaaagaag gatttctctg
    36181 cataaatcaa cccctctatc acttttttcc tgatttttgc tatctttttt tcacccgatt
    36241 gactaaacag atagtaacca atagaagaaa acaaggcttg accaataaaa atcaaaaacg
    36301 attgaaatac tttggaacct atattttcaa tagaactccc atctattaaa ccctttaaga
    36361 taaggggaag caacaaagca agtagactag acagaacaag taagaaactc cccataatca
    36421 ccttagtatc tactcttaat aattttaatt tcataaatac tccttataat atttcaacgg
    36481 ataaagtcga gaataactca atttgaggat aaaatctaat aaatcttcct ataacaaaac
    36541 gcataacatc taggatttta tatacctgat attatgcgtt tttaagcaca aagacttctt
    36601 acacaaactt atctacaatt agattttatt tgacatgttt tgccaattct tcttgggctt
    36661 ttttattgga ttcttctttt tctttcaacc atttttctct ggcttttgca tattcgtctg
    36721 ttgtgacaat cttatcttgt actttgaggt atttatatga ttcaacccct tttgtaccgg
    36781 ttaaaccata ggcagcagca aatggtacgg ttcttctcaa tgatggtgtt cccccacgcg
    36841 aaacacttgg aagaactaaa gaactatcaa tcaaccaagc ttgaatatca gcatatttct
    36901 cataacgttt ggctggatct tgctctttat tagcttcttc caacatttga gtatagacat
    36961 ccagtccaac tgccttagcc ttgtcattgg cttctccagg ctctagtcca agattttgta
    37021 gaactcctcc actattagta ttaaaaatat cgagataggt tgacgggtct tgataatcag
    37081 gtccccaacc gccatgatat aaatcatagt ctttctgagc agctgtttga gcaaagtagc
    37141 ctgaactgtc aaactcatct gatgttaatt gctgaatgtc aatcactaca ttatcagaac
    37201 ctaaaacaga ttcaattgat tgtttgatag aactaactcc ttgtatgcct actttatctg
    37261 ttacttccac agtcttatcc aagtggattg ggaattgaac accctttgct tcgagttctt
    37321 tcttagcttc cgcaaactta gccttggctt tctcaggatt gtagtaaggg tcttgaccat
    37381 ccgcaaagtt gataccttgc cattccttac catagttgac catcttagag gctacaactt
    37441 caccaaagtc ttttcccttg atactgacaa agtttggagg aaccactagg ttacgcaaaa
    37501 tctttgttgc accttctttc ccttcagact gagccccata agatgttctg tcaaaagcaa
    37561 aattgatagc ctgacggaag tttttattga gaactgcttc ctgagtcgat ttcttttcaa
    37621 tgtcacttgt tttagaagta taattgtaag acttcctatc taggttaaaa ttaaagaaat
    37681 atgaagttga attttgcata ctatagatga tattgttttt gtatttttct ttaatccctt
    37741 catagctgga gctgttagga aaaagacgag ccgtagtata agcaccagct gtaaaattac
    37801 gttccagtga ttcttggtcg ctaccatcat agtaggtcaa tttcacatcg tctacaaaga
    37861 cattcttagc atcccagtaa ttagggtttt tcttatattc aatagcagat tttgagacaa
    37921 gtgctttcat caagaaaggt ccattgtaca aaatactaga tggatccgcc ttcccaaaat
    37981 catccccttt tgatttcagg aaatctgcat taacaggaaa aagtatcgtt gcaagtgttt
    38041 ttgaattcca gtaaagttct ggtttaacca aagtatattg aaccgtttgg tcatcaagtg
    38101 ccttgacacc gacagttgaa aagtcgcttg ttttaccagt gatatagtca tccaaaccag
    38161 caacagagtc ctgcactaga tacaaggctt ctgatttttt atcagctgca tattgcaaac
    38221 ctgtcacaaa atcctgggca gttacaggcg catattcttc tccctcagaa gtaaaccact
    38281 tggcatcctt acgaagtttg taggtatagg tcaaaccgtc ctgagaaaca gtccaatcct
    38341 ctgctaatga tggaataata ttcccatatt ggtcattttc taataacccg tctaccaaat
    38401 ttgcaacaat atcggatgtt gctgcgcggt tttctgctag atagttcaag ctagatggat
    38461 cacttgaata aacatagttg taggtttttg acgccgtgct agaatttcca cacgcgctca
    38521 ataaaactcc tgtacccagg acaagacctg ccaaggttag atatttgctc ttagactttt
    38581 tcatttccgg aacctcctgc tttaaatatt tgttttatta tacaactctt ggtttgttta
    38641 gtcaattgtt ttttccaaaa aatcaaaaaa acctcatttt ctatttttga aagataattt
    38701 tagctatttt tacgctaaaa aaggaataag tttcaagttc tcctaaaaga ttgttcaact
    38761 tattcctttt atttataaat gctaccttac gaaagcttaa attttgctcg caggcgatct
    38821 gcttgggctt ttcctattac cttatctaat aaataggtac gcagactcat aaccatataa
    38881 agtccacccc ccatggcacc gacaagagct acataaaaga agctccacaa acgtccactt
    38941 ggttggaaga aaaatcctaa cagccactgg atggttccta ttaacagaaa catgactagg
    39001 gtcagcaaac tgattaaaat agttcgcttc aaaatcacct tgcgcttgac accagttact
    39061 ttacaaatat cccgatacat caagacgtta ggaatgatga gagcaatggt tgttgaaatc
    39121 aaaggaccat aactgtggaa gagggcgatg gtaggtagtt gcaagactag cttggcaata
    39181 gaaccataga taaaatagag aacggccttg cggttgcgga acatggcctg aagcattgga
    39241 gacaagacca tgtacaagcc taaaataata gactgcaaaa ctgcaaagac aaataagccc
    39301 agagccaaac tatctggctt accatagaag actgtatata gaggttctcc taccataacc
    39361 actccaaccg ttgctggtag caagaacata aagagtaggg tgagactgtc ctgaacgaga
    39421 cgagaagctg ctttcaagtc ccccttgaca tagttttccg tcaaaagtgg caaaccaaca
    39481 ctcccaatcg aaacccctac agaaatcaaa atcatcgtga ttttattagg attggctgag
    39541 aaataagaaa acatgacaac caagtcctca ttgctgtagt tggtaaacca gctcatacta
    39601 ttgataaagg tcagctgatc caaaatctgg aagagctgga tggcagaccc tgtcaggata
    39661 aaaggaatgg cttccttaat ggtatcaacc aagagacgct tactgttaat cttatctcct
    39721 gtttcaaaga ctcttttgag tgaaccttct tgggcaagga aataaatcaa gactgcaaaa
    39781 ctggctacca taccgacaaa ggcagcaaag gttgattggg taacggctgc tagataatct
    39841 cctgaaccga gcttcataat gataaaggtt gctaggagca tccagataac acgaatgacc
    39901 tgctcagcaa tttggctcat ggcatagggt ttgaggttat tcatcccttg gaaaaatcct
    39961 cggataacac tcatagacgg gaaaatcaag actccccaag ccaagctttg catgattggg
    40021 atcaagtctt tgcccacgcc agacaagtct gctagccaag gagcaaagac atacaagact
    40081 aaagcaaaaa ccaggcctag tcctgtcata aagcctaaga aactccgaat cagggcaaag
    40141 ctatgctctt cttctcgcat ggtattatac ttggcaactt gcttggccac cgcaactgga
    40201 atccccgctg ttgaaaccaa caagaaccaa gcatagatat tgtaacccat ggtaaagaga
    40261 ccatttgcct tagctgcata agcccccatc cagatgtacc aagggataat gtaaacagcc
    40321 ccgagtaggc gactgataaa gttactagcc gttagccaag cagtcccccg taacatctgg
    40381 gcctgctggt gattgttttc gtgcgacata gattcctcat tcaattttga tagctaggaa
    40441 aaactcctta tcttccatta taaacttttc cttgttactt gtaaatttac gactttcggt
    40501 ttacaataga aagtatgatt aagattgaaa ccgtattaga tattttaaag aaagatggcc
    40561 tttttcgcga aattattgac caaggtcatt accactacaa ctacagcaaa gttatttttg
    40621 atagcatcag ctacgacagc cgaaaagtaa cagaagacac tctttttttc gcaaaaggcg
    40681 ctgcctttaa aaaagaatac cttctttctg ctataacaca aggattagct tggtatgtag
    40741 ctgaaaagga ctacgaagtc ggtatccctg tcatcattgt gaacgatata aagaaagcca
    40801 tgagtttgat tgccatggag ttctatggta atccacagga aaaactcaaa ctccttgcct
    40861 ttactggtac taagggtaag acaacagcag cctatttcgc ctataacatc ttatctcaag
    40921 ggcatagacc tgctatgttg tcgaccatga acacaactct tgatggcgag actttcttta
    40981 agtcagcgtt gacaacccct gagagtattg acctctttga catgatgaat caggctgtgc
    41041 aaaatgaccg tacccacctc atcatggaag tctccagtca agcctatctg gtcaaacgtg
    41101 tctatggtct aacctttgat gtgggagttt tcctaaatat cagcccagac catatcggcc
    41161 cgattgaaca ccctagcttt gaagactatt tctaccacaa gcgtctcttg atggaaaaga
    41221 gccgagcagt catcattaac agtgacatgg accacttctc agtcttgaaa gaacaggttg
    41281 aagatcaaga ccatgatttc tatggtagcc aatttgataa ccaaatcgag aattccaaag
    41341 cctttagctt ttcagctacg ggtaaactcg ctggagatta tgatattcaa ctcattggca
    41401 acttcaacca agaaaatgca gttgctgctg gacttgcttg tctccgtctc ggagcaagtc
    41461 ttgaggacat caaaaaaggc atcgctgcaa cccgcgttcc tggtcgtatg gaagtcctca
    41521 ctcagaaaaa tggagccaag gtcttcatcg actatgccca caatggggat agtctgaaaa
    41581 aactcatcaa tgtggttgaa actcatcaaa ccggaaagat tgctctggtt ctgggatcaa
    41641 caggaaacaa gggagaaagt cgtcgtaagg actttggcct cctcctcaat caacaccctg
    41701 agattcaagt ctttctgact gctgatgacc ctaactatga agacccaatg gccattgcag
    41761 atgaaattag tagctacatc aatcatcctg ttgaaaagat tgcggatcgc caagaagcca
    41821 tcaaggcggc aatggctatc acaaatcacg aattagatgc agttattatt gcgggtaagg
    41881 gagtcgattg ttaccaaatc atccagggca agaaagaatc ctacccagga gatacagccg
    41941 tcgcagaaaa ttatttataa gaatagaaaa aatcaaggga aaatgaaacc cttgattttt
    42001 tcctattatt tagtaaaaac gtttttcaaa ccttcaacgg caccttctac agcacctttt
    42061 gcgtcttcta caacgtcttt tgccttagca actgtttttt caacagctcc ttcaagttct
    42121 gtcttgctgt ctccagtaac tttaccaaaa ccttctttga cagcgcctgt tgcttgttcc
    42181 aatttgtttt caagtgacat atgattgtct cctttagttt attccgatat gtgttaccgg
    42241 ttacatatag tttataccga atactaagga aagtcaaaca atgtgctcag aaacaagaaa
    42301 tcacgctaag tagaaagtta atctctcctt atcaaaatcg atagccaact catactttct
    42361 atcttcattt tgcacaatat agcctaagac aaccaaactg tccacaaaga tatcacggca
    42421 tttctgcata agctggtctt ttttgagaaa tttcaacaaa aaagccgtca tatacttgag
    42481 ggcatactca ggattaacat ctcctaaaat gtcatagagc tcctgctgtt tttctgtcaa
    42541 aggatactgc tgtttgacct tgtaaaaata attggacagg gtcattttaa tgcgcgcaaa
    42601 gtccgtcttt tcaactaaaa tagctgcatt gatttgattg cgcaattccg tctcaaaact
    42661 ctgctccaac aaggcttgat agaccggact agcttctctg acaaaaatct cttgatccag
    42721 ttcaagacta tcaagtgatt caagcgtagg aaaattgagg taatagcgct tattttcacg
    42781 tagaatcaag cctgccttta tatactcttc catgagttta tcaactgcaa catctggaaa
    42841 ttgagcctta atttcccgta gaatcacatc ctcatactgg tccagatagc ggatcaattc
    42901 tccaaaaatg gctgtctcgt caaacgagat ggattaaaaa tctgaatcat gaagatccct
    42961 ttctttacat tgtaacagag gcgatgctgc caactgacta ggattggtac cagcttggtt
    43021 cagaggaaca ggcagaccta gttctatgta atactccctc caaaaatcac taatctcctg
    43081 ctccccatct ccaaatttca taggaatagt ttcaaaaata ggtaggattt ctgctatata
    43141 ctgggagcag tagaaaccag ctgcatctgg atagaaagaa gcattgtagg gtgctccaag
    43201 atgtttgcaa gctctttcct tcaccgactg gatatccatt tctgggtaaa catagaggtc
    43261 gtataaatga ttggactcaa agaagtctgc cggttcttga cagacaacac cagcctgtcc
    43321 actagcatga taaatcatcc catccaaata aatggcaaca tggctatagt tacctgtgga
    43381 agtctggatg gcctgtccca tgtctgaccc atctctcaca aaaatcaaat cgccattttc
    43441 taacatactt cactcctaga aaaaaggagc cgaaactcct ttcgatataa ggcaaactag
    43501 actttccgat tttgagctga cacccaaaat cttacgcatt aaagctttca gtcaattgag
    43561 gtaccacttg tttcttacgt gaaacggcac cagcaaggaa ggcatgattg ttttcaagtt
    43621 tgaagttgaa agccgcttcg accttgtcca tattggcacc aagagccaag atttctgagt
    43681 ttgagttgac gatatctgta atcatcaaga caaagtcaga gtagccgttt gattcgttgg
    43741 cagcttgcat tgcagcttca atttctgctt ggcgttccaa aacttcagcg atgtcaactg
    43801 tgttcacttg ggcaacacgg acattatttc cgttgagttc aaaagtctta gcatcgatgt
    43861 caatcaattc ttcagcagat ttgctagcca agttggtacc agctttcaac attgctaaac
    43921 catattcttc caagttcaca ccagccaatt cagccaattc aggagcaatg attttatctg
    43981 ttgggtgtgt tgttggtgat ttcaaaagaa gggtatctga aatcaaacct gaaagcatca
    44041 aacctgcaat ctctttaggc acagctacac catgttcttt gaacatacgg taaacgattg
    44101 aagacgctga tccaactggc tccaaacgca tgtaaagtgg gcttgcagtt tcaaagttag
    44161 ccacacggtg gtggtctaca acaccataaa cttctacttc agcgatatct gatacagatt
    44221 gttggaattc attgtggtca gtcaagataa cttgctctgc cccctctgct ttggcagaag
    44281 tgataatacg tggtgcttcc acaccaaaat agttcaagac aaaggctgtt tcttcatttg
    44341 gagttccaag ggcaacagct tccgtatcca aaccgtaagc ttcttttgca aggtaggcaa
    44401 aagctacaga tgacccgatg gcatctgagt ctggattttg gtgaccaaat actagaatct
    44461 tggacatgat aatacctcat tttgtttatt ttctttattg tagcattttt ttcgcttttt
    44521 gacaaaggta agaggagtca aaggactccc cacgattctt caaaataact gagtaaattt
    44581 ctatcttgat tttcagataa aaattcttcc ttctgtggcc tcttcttacg cttgagaaga
    44641 gcttcagccg acatggcttc ttccttactg gcaaaacctt gagcatagat aagtttgact
    44701 ggcaagcgtg ctcgtgtata tttggctccc ttcccactat tgtggatagc gaggcgtctt
    44761 ctcatatcag tcgtatagcc tatatagtag gatccatcac gacactccag aacgtacata
    44821 taagccttat gatccataat aaatctcttc gatttcgggc gtataagagc catcatcatt
    44881 gtggacaatc aaaggaggta agaccttaaa gccacttgtt gagccatcct tgatcgcctc
    44941 aatcaaaagc atattggctt ccttttctct ttttggataa acaaactgca ggcgcttagg
    45001 ggctagatta tgtcgtttta acgtatccaa aatatccaga agtcgatcag gacgatgaac
    45061 catggccaaa cgcccattag acttgagaat actctgggca ctacgacaga tttcttccaa
    45121 attagtcgtg atttcgtgtc gagccaagag ataatgttca ctctcgttca gattagaata
    45181 aggatccacc ttgaaatagg gtggattaca caaaatcata tccaccttac tcccctgaat
    45241 gtgagcaggc atatttttca aatcatcgca gatgacctgc atttgctcct ctaatccatt
    45301 caaacggaca gagcgttcag ccatatccgc caaacgctcc tgaatctcaa cagacaatat
    45361 ctgtgcttga gtacgagtgc tagcaaaaag ccccactgct ccattcccag cacagaaatc
    45421 cacaatcaac cccttcttag gaaaacgtgg aaatcgtgat aagagaacac tatccaccga
    45481 atagctaaaa acctctctat tttgaatgat tttgatatct gtcgaaaaga gctggttaat
    45541 gcgctctcct gattttaata attgttcttc ttccatggtc ctattatagc aaattcatat
    45601 taacattaca aaaaatataa aactctaaac tacttcttct tttttaaatg gtgcagggct
    45661 tctccagtcc agattggtag cattcgtcga aagggagcaa aaccgtagtt aaagcggtcg
    45721 cttgaaaagc gtctccgtct aggaaactgg tacttttttt cctccaaagt gcggatagaa
    45781 agactggctt tccccgtaaa ttcatctaaa tccactacct gaacttgaac ctcttcatcg
    45841 actttcaagg tttcatgaat attttcaata aatcctgtcc gaatctctga aatgtgaatc
    45901 agccccgtat cacccgtctc taactcaaca aaggcaccgt agggctgaat ccctgtaata
    45961 cgccccttta gcttatcacc gattttcatc ttagtcctcg atttcaatag tttcaattac
    46021 aacatcttca actggcttgt ccatagctcc tgtctcaaca gcagcaatgg catccaagac
    46081 agcgtaagat gcttcatcag ctaactgacc aaaaaccgtg tgacggcggt ctaggtgagg
    46141 tgtcccacct tgattggcat agatttctgc aatcggttct ggccaaccac cacgagtaat
    46201 ttctttctta gaataaggta ggtgttggtt ttgcacgata aagaactggc tgccgttggt
    46261 atttggacca gcatttgcca tggaaagagc accacggata ttgtaaagct cttctgagaa
    46321 ttcatcctca aaagattcgc cgtagattga ctcgccaccc ataccagttc cagttgggtc
    46381 tccaccttgg atcataaagt ccttgataat acggtggaaa atgacaccat catagtagcc
    46441 atcttttgaa agagatacaa agttagccac tgttttagga gcatgttcag ggaaaagctt
    46501 gatacgtaag tctccgtgat tggtcttaat agtcgcaaga ggaccttcta ctgtttcaat
    46561 gtctacttgt ggaaaatgca attctttttc taccatacca aatacttcta aggcatcaaa
    46621 aatgccatct tcttctaatg tttttgtaat ataatctgct ttttctttga ttttatcatg
    46681 agaaattccc atggcaacgc tgattccagc ataatcaaag agttccaagt cgttgagacc
    46741 atctccaaaa accatgacct tctctggttt caagccaagg tgttccacaa ccttttccac
    46801 ccccgtcgct ttggagcctg aaatcggcac aatatcagac gaatgttgat gccaacgaac
    46861 catgcgaagt ttgtctgaga gactgtcagg caagtgcaag tcatctccct tatcttcaaa
    46921 agtccacatc tgatagatat cttctttttc atggaaatcg ggatctacat ctaagtcggg
    46981 ataaattgga ttgatagctt cactcatcat atcggtgcga atcgacaact tggcatcatg
    47041 actcccaacc aagccatact caattccttc ttgcttagcc caagagatat actcctcaac
    47101 atctgacttt tcaatctgat gctgataaat gacctgacct tttttatctt cgatataagc
    47161 cccattcaaa gttacaaaaa agtcaggctt gagatcacga atctctggaa caacaccaaa
    47221 aatgccacgt ccagaggcga ttcctgttaa aattcctttt tcacgcaact gtttaaaaac
    47281 agtgggaatt gtagttggaa taaaccctgt ctttgaattc cgcaatgtat catcaatatc
    47341 aaaaaagaca atcttgatct tctttgcctt gtatcttaat ttcgcgtcca tctcactacc
    47401 tctttcaatc taactctttc cattatatca taaagtaggc aaatccccta ttttcaaaaa
    47461 gtttatcatt tttattttaa tttcttggat gagaaaaaag acatatttat gaaaaagctc
    47521 catcgtgctt ttaatgtgtt ctcttgtttt caaactcgta aaaagggagc cactgagcct
    47581 aactcgctct ctcatttcaa agtttgtgaa aaaagaccca ttggggtctt aattcgcttt
    47641 cttgttttca agctcatgaa aaagagaccc aaccgggtct tttctttaat cttcgtttac
    47701 gaaaggcatc aaagccatta cgcgagcgcg tttgatagct gttgttactt tacgttggtt
    47761 tttagctgaa gttcctgtta cacgacgagg aaggattttc ccacgttctg aaacgaaacg
    47821 gctaagaagc tcagtatctt tgtaatcaac atattcaatt ttgtttgctg cgatgtaatc
    47881 aactttttta cggcgtttga atccgccacg acgttgttga gccatgtttt ttctccttta
    47941 taagtttagt tgtccattag aatggtaaat catcatctga aatatccaat gggtttgttg
    48001 ctccaaatgg attttcatta cgtgaaaagt ctggtactga atttgtaggt gctgaatagt
    48061 ttgcagttgg tgcagagtaa gctccacctg tgtgaccctc acgcacacta cggctttcca
    48121 acatttggaa attctcagcc acgacctctg tcacgtagac acgttgtcct tgctggttat
    48181 cgtaactacg agtctggata cgacctgtca ccccgataag tgagcctttt ttagcccagt
    48241 tagcaagatt ttcagcctgt tggcgccaca taacgacatt tataaaatca gcctcacgtt
    48301 caccattttg actcttaaat gtacggttta ctgcaagagt aaaagtcgca actgctacat
    48361 ttgatggggt ataacgcaac tcagcgtcac gtgtcatacg ccctacaagt acaacattgt
    48421 taatcatagt ttaccttctt acgcgtcaat tttgacgatc atgtgacgaa gaatgtcagc
    48481 gttgattttt gaaagacggt caaactcttt aagagctgca tcgtcatttg cttcaacgtt
    48541 aacgatgtgg taaagtcctt cacggaaatc ttggatttcg tatgcaagac gacgtttttc
    48601 ccaagttttt gattcaacaa cagttgcacc gttgtcagtc aaaatagagt caaaacgtgc
    48661 taccaaagcg tttttagctt cttcttcaat gtttggacga atgatataaa gaatttcgta
    48721 tttagccatt gatatgttcc tccttttggt ctaatgaccc caagactttg caaggggtaa
    48781 gtgaggttcg ctcacaataa actattatac tagaaaaaat ttttttacgc aagtaaaaac
    48841 actagaattc gaaaaaacgc cacatgggcg ttttcctgtt cttatggttt gatacggtgc
    48901 aacatacgtg ggaatggaat agcttcacgg atatgttttg ttcctgctgc gaaggttacc
    48961 atacgttcga taccgatacc aaatcctccg tgtggaactg taccgtattt acgaaggtca
    49021 aggtagaatt catattctgt acgatccatg ccaagttcat ccatcttagc gacaagggca
    49081 tcgtaatctt cctcacgcat agacccaccg ataatttctc catagccttc tggagcaagc
    49141 aagtctgcac aaagcacgcg ctctggattt ccaggaactg gtttcatgta gaaggccttg
    49201 atggctgctg gatagttctt gacaaatgtt ggcacaccaa agtggtttga aatccaagtt
    49261 tcgtgtggtg acccaaagtc atcaccatgc tcaagatgct cgtagtcagc atcttcatca
    49321 ttttcatgct cttgcaagag gtcaatggct tgatcgtaag tgatacgttt gaatggctct
    49381 gcaatgtagc gtttcaagag ttctgtatca cgttccaagg tttccaaggc ttgaggcgcg
    49441 cggtcaagaa caccttgtag aagagctttc acataagctt cttgcaagtc aagcgactca
    49501 tcatgtgtca agtatgagta ctcagcatcc atcatccaga actcagtcaa gtgacggcgt
    49561 gtttttgatt tttcagcacg gaaaactgga ccaaagtcaa agacacgacc aagagccata
    49621 gcccctgctt ctaggtaaag ctgacctgat tggctcaagt aggctggcgt tccgaagtag
    49681 tcagtttcaa agagttctgt agaatcttct gccgcatttc ctgaaagaat tgggctgtca
    49741 aacttcataa aaccgttctt gtcaaagaac tcataagttg catagataat agcgttacgg
    49801 atttgcaaca cagctacttg cttacgagag cgtagccaca agtgacggtt atccatcaaa
    49861 aagtctgttc cgtgttcttt tggtgtgatt gggtagtctt gagattcacc gatcacttcg
    49921 atgtctgtga tgtccaactc atagccaaat ttagaacgtt cgtcctcttt gacaatacct
    49981 gtcacataaa cagacgtttc ttggctcaag cgtttgataa catcaaactt ctcaagtccc
    50041 acttcttcac caaatttttc gacaaagttt ggtttaaaag ccacaccttg aaagaaggct
    50101 gttccatcac gcaattgtaa gaaagcgatt ttcccttttc ctgatttgtt ggcaacccaa
    50161 gcgccaatcg tcacttcctg accaacatag tcttttacat caataatcgt tacacgtttt
    50221 gtcattattt ttccttttct tttttattct ttatggcaaa ccacctctat attgttccca
    50281 tccaggtcaa tcataaaagc agcataataa atcggatgct cacttcgata accaggaacc
    50341 ccattgtctc gcccacctgc ctctaagcca gcctcataac aagcctgaac ttcttcctta
    50401 ttttctgcta aaaaagcaaa atgaacagga tcttgtgttc cctgagtcag ccaaaaatca
    50461 ccaccaggat gagggctgtt cggggataga aaactaatta gagaactagt cttaaaagcc
    50521 aatttatagt ccaaaggagc gagaaaactc ctataaaatc cttctgaaat ttgtaaatcc
    50581 tttaccttaa tctcaaaatg atcaatcatt ctcactaccc ataaatgctt tcaagcgttc
    50641 gactgcttct ttaagcgtgt ctaggtctgt cgcatagctg aggcggacat tttctggtgc
    50701 tccaaatcca gctcctgtta ccaaggccac ttcggcttct tctaagatag cagttgtaaa
    50761 gtctgtcaca tccgtgtagc ctttcatctc catggccttt ttgacatttg ggaagagata
    50821 gaaggcccct tgtggtttga ccacttcaaa tcctggcacc tctgcaagga ggggatagat
    50881 ggtattaaga cgttcctcaa aggcctgacg catgctttct acagtatctt gctcacctga
    50941 tagagcctca actgctgcat attgggctac tgctgacgga ttcgaagttg tttgacctgc
    51001 aatcttggac atggcagcga taatgtctgc ttctccaacg gcataaccaa tccgccaacc
    51061 agtcatggca taggttttag acacaccatt gatgaccact gtttgcttgc gaatcgcttc
    51121 cgataggcta gaaatcggtg tgaactcatg accattataa accaagcggc catagatatc
    51181 atctgctagg atgagaatat cattttctac agcccagttt ccaattgcca agagttcctc
    51241 acgggtgtaa atcatacctg tgggattaga tggcgaattc agcaccaaaa ccttggtctt
    51301 gtcagtgcga gctgcttcta actgctctac ggtcacctta aagtgattgt cttccttagc
    51361 agaaacaaag acgggaacgc cttctgccat cttgacctga tctccatagc taacccagta
    51421 tggggttggg atgatgactt catcacctgg attgaccaca gccataaaga aggtatagag
    51481 agaatatttg gctcccgcag cgactgtcac ttgatttgac gctacagaat agccgtaaaa
    51541 gcgctcaaag tagctattga ccaccgcctt aagctctggc agacctgagg ttactgtata
    51601 aaaagaagca cgcccatctc gaatcgatgc aatggcggca tcttggatat ttttgggagt
    51661 agtgaaatct ggctcaccca aggttagaga caaaatatct ctaccctcag ccttcagtgc
    51721 tttggcacgg gctccagcag ccaaagtcac actttcttcc atttctaaaa cacggttgga
    51781 tagtttcata ggccctcctt attgaccaat gctcctgttt caaaatctac tagataaaaa
    51841 tcagatcctg acttaacttc ccagattggc ttgtcttgat aacgaccaaa ggttatcttg
    51901 tcaatctcgc cagctccctt ttccttagaa accgtttctg ctttttcttg tgaaataccc
    51961 tgatttagct gataaacgta aatcttatgg tcatctttac caatcaggac agcaagcgct
    52021 tcttgctgtt tattacgacc aagaacgctg taataagatt ccaagccatt gtataaatca
    52081 acctgatcag cctgctctaa tcctgcatac tgctgagcta atttttctcc ttcactttta
    52141 gctgtttgat agggtttcat gctaagagaa accatataca gaaaggaagc actgataacc
    52201 acaaacaaaa tcgtcatccc tagaccatac tgccacagta gattattttt tgctttgttt
    52261 tgtctttttt tcactcgtct attttaccat ctattaagct ttattacaag tgaatataag
    52321 aatactcttc gaaaatctct tcaaaccatg tcagctttat ctgcaacctc aaagctgtgc
    52381 tttgagcaac caattctatt tctcccttca aacaaaaccg attttgaaag tgaaacagtt
    52441 cttacttttt cagtcacaaa tgactagagt ttccgaaatt ttacaatttt caaataaact
    52501 ctgagcaaat ttcttgcaag ttcttttgtt ttgttgtaat atattttata acaacgagag
    52561 agttctcgaa attttaagaa aaaggagaca catcatgtct aaaaaagtat tatttatcgt
    52621 cggatcacta cgtcaaggtt ctttcaacca ccaaatggcg ctcgaagctg agaaagcact
    52681 tgctggtaaa gcggaagtta gctaccttga ttattcagcc cttcctctct tcagccaaga
    52741 tttggaagtt ccaacacatc cagctgtagc tgctgctcgt gaagcagttc tcgttgcgga
    52801 tgctatctgg attttctctc cagtctacaa cttctctatc cctggtacag tgaaaaactt
    52861 gcttgactgg ctatctcgtg cccttgactt gtctgataca cgtggcgttt ctgcccttca
    52921 agacaagttt gtcacagtat catctgtagc caatgcaggg cacgatcaac ttttcgctat
    52981 ctacaaagac ctcttgccat ttatccgtac acaaggcgtt ggtgatttca ctgctgcacg
    53041 tgttaatgac tctgcctggg cagacggaaa attggttctt gaagaaacag tcctaaactc
    53101 acttgaaaaa caagctcaag acttggtcga agctatcaag taactaacac tcaataaaaa
    53161 tcaaaaagca aactaggaag ctagccgcaa gctactcaaa gcactgcttt gaggttgtag
    53221 atagaactga cgaagtcagt aacatatata cggtaaggcg acactgacat ggcttgaaga
    53281 gattttcgaa gagtataaca taataaaagc gaacaagact acttttctga cgctcagaag
    53341 actagcttgt tcgctttttt ctcatttata aactaaaata gctgatgata catattgcca
    53401 aatacaaaat atctgatttc tatacttcct ttacaaaaac caatccctgt ggttgtgaca
    53461 aatcttctcg gtaaacaaat ccagcaaagt tcaagcgacg tgcttccccc acagtttgta
    53521 cttgattttc tattaaagct gttagaaagg ccccgcgcgc tttcttggag atagttgagt
    53581 gaatcttcag ctgaccgcct ctatcctcca tgaatttgaa ggtcaccatc tttgctctga
    53641 tttccttaga aaatacagtc tcaaactctg atgacaagag agagaaaatc acttcttcct
    53701 tcttcagagc ttcatcatag actgccttcc aatggctctt caaagtctta ccagcaactt
    53761 ttaatttcat caaaaaatcc aaacggtgag gagccatggg tgacaaggct ggaacaacac
    53821 cgtacaaagc cgaggtaatg aagacatgat tttcaagata atcttgttcc gcctcggtca
    53881 gcttatctct cttaatgttg cggtacataa gcccatcaaa aagtttcaag gctggatagt
    53941 gttgagtagt ttgccttttc aaagcttgga tattttgaaa ttcttccgcc gctttctcag
    54001 ctgatacctt gtagaaactc tccaattgac tggcagaata gagagccaag gcatcaagca
    54061 cggcctgact ttctggtttt aaagaaattg cctcgatact tggcaagtct gtgttcattt
    54121 cttttgctgt tgggattaaa attttcatat tgatagtgta gcatattttt tagccacaac
    54181 caagaaattc atttgaaaaa cctcggtttg accgaggttt ttctatttat ttgggccatc
    54241 ctaaccagac agccacgaga acaagggctg tgccagctaa acttgttaag atagataaga
    54301 atttatcttt tttctccttg aactgagaaa aacctatctt caaagcgagc agtccgagta
    54361 gcattgaagc aaccatcaaa taaaaaccca tttctttgtc ctccattagg cttaatttac
    54421 cttattataa catatacttt ctgaaaaaaa cctattttta ccgtagctta aaggtcttga
    54481 gataattgtc ttttcctact tgaccttcga aggttttacc attttcaagg taaggaaggt
    54541 catcggatac tgaagccttg accttgtata tcttgccatc aactttaaag aagtagacag
    54601 tgtctccctt gataacagct gatttgaggt ctgctactac tccattgatg ctttctgtcg
    54661 ttgcattgtc aatttcaagg tcgtttttat tggcatactt gctgagcatc tcttccactg
    54721 tagtagcaac gataacattt tggtactcga ctgcgtctac cagggcgtac tctttgacca
    54781 agccagcatt gtccttcaag cccatgatgt agagaggctt gtcattgagg ttgatgagga
    54841 ttgggaaggt tgctttgtag gatttctcct gaacagcacc ttctgctgat tcacgggctg
    54901 attcttctgt cgcagaagcc aagctatact tagtgatttc tcctgttcgc atattttcaa
    54961 ggatgaaacc aagattactc tcatccgcat tagccgacgt cacacctgtg tagagataga
    55021 tgtcattacc gatagacaag taattatagc ccttggtagt ctgggtcacg tttttcttgg
    55081 aaatcatggc attcaagaaa ccgtccttgt acttgccgtt gtagttgatt tgctcaatgg
    55141 tttcctctgc tggatagatc ctgtccaccc attctggaac atctgataag ctgtattcct
    55201 tggtttctcc atttgtagca tccaagataa tgactgaagc aggacgagga acagcaagtc
    55261 caaattgctt ttggtaaacc gttgctacat agaaaggatt gccctcatcg tccacctcaa
    55321 aagatggagt tttaaagatt ttggtcgggt acttcaagcg caggtgacgt ttgacatcac
    55381 ggttaaaata ctccgagtct gaatacttga ttggtgtctt caagtccacc aaatccgcat
    55441 ttccagttac catgtccacc ttgatatact caccgattcc cttggcttga ttgttaaacc
    55501 atttgatagg gtctgcatat tctagtggtg tgacccgata aggtttccca tcaattgtca
    55561 attgggtata ggtatctgcc gctacgtatt gcgacacctt atcggttagg gaacccaagt
    55621 agcggtctcc aattttttca gcagtacttc tatctaggat aggaacctta ctggtgtcac
    55681 tcctaggaaa ttcagtaaag tctttttccg taaccgtgac tacattggca taatttttag
    55741 cctgaaacat gctggaagtt accaaggaaa ccaaagctgc caagagaaga attcctccaa
    55801 tcgaagctaa cagaattttc cctaaccgat tgattttgaa accctcaaga tttaaggcag
    55861 cttccgcctt accgtggcgc acatgaaccg ttttgacaag gtttatcccc ttgccaaagc
    55921 caaataagat tgccacaact aacaaatgcc cacagaggaa gaagagaaat tcccagctgg
    55981 tcaggttaag gggcggtaaa aagatatacc aggtcgttgc gataaaaata agttcaaaga
    56041 ctattcgttt catttgcttt cctcctaaat gattcgtcct tccaagtgat ccagctcatg
    56101 ctggcaaatc tgagctggga agcctgtcaa ggtaatggtc tgttcctgcc acttgctgtc
    56161 acgataggca agccttatgg tttcataacg cttagttgat ctcacaccta ccaaggacaa
    56221 acagccttct tctgcctcat aagatccttc aaaggacaga agcactgggt taaacatgac
    56281 cacgggaacc aagccaagat taaagataat cacgcgcttc tgcaccccaa tcatattggc
    56341 agctagacca acacaggtat cacgatttgc taagagtgta tcctgcaaat ctctggcaag
    56401 ataaaggtcc tcctgacttg ccggctgaga cacttgagat aaaaataaga tatccttcac
    56461 aattttcttt tccacttcct cacactcctc ttgcttttta ctatattata gcaattatag
    56521 cacaaaagcc gataactgca aaccctttcc ctcaactgta gcaaaaagcc atccgaagat
    56581 gacttttttg ctatttaatt tctgtataag ttacttccaa tccacgctta acagctggac
    56641 gattggcaat tttttctgcc cattttacta gattttgata acttgaggca tccaagaatt
    56701 ttgcagaacc ttggtaaaga tttccttgaa ctaactgtcc ataccaagac cagatagcaa
    56761 tatctgcaat cgtatagtca ttgcctgcaa tataaggttt ctgagccaat tccttatcca
    56821 ataaatccaa ctggcgtttc acttccatcg taaaacggtt aataggatat tccaattttt
    56881 caggagcata attgaagaaa tgtccaaatc ccccacctag aaaaggtgct gcacctgctt
    56941 gccagaatag ccaattcaaa acttctacct tttccacagg attacttggt aaaaaggctc
    57001 caaatttctc agcaaggtaa agaagaatat gagcagactc aaagactctt acgctttcag
    57061 tacctgactg gtccaataag gctggaatct tggaatttgg attgagcttc acaaagtctg
    57121 agccgaattg atccccatcc atgatagcaa tcttatacaa gtcgtaagcc gcttccttaa
    57181 aaccagcttc tagtaattct tccaataaga tagtaacctt cacaccattt ggtgttccca
    57241 gtgaataaag ctgaaaagct tgttctcctt ttggcaagtt ttgttcgaaa cgggcacctg
    57301 ctgttggtct gtttagcccc gtaaaagctc cttgattact agcttcatcc tgccatacgg
    57361 tcggtaattg atatgctgac atccgaaacc tcccttaaat cgcattcttg tcaaaaccga
    57421 gtttgcgttg aataaactta acgatttcga cgatgataat cattgagaag cttccagcca
    57481 taacaattcc ccattgtgac aagtctagtt tggttacgtg gaagattcct tcaagcggtt
    57541 ctacaacgat tgttgccatg agaaggataa aggataccaa gatggaccag ttaaaggtct
    57601 tagacttgaa tgggccaact gtcaagatgg attggtagac agacttgaca ttgtaggcat
    57661 ggaagagctg aatcaaacca agggttgcaa aggccatcgt tagggcatct gcatgaatag
    57721 catgattgtc acccacatga actgggtaag caatcgcaag gccataaaca ctcataacaa
    57781 gagctgcttg gagtacacct tgataaatga tagaactcaa aacaccacct gagaagaagc
    57841 ttgccttgcg tccacgtggt ttatgattca tgacgccagg ttctgcaggt tcaacaccaa
    57901 gagcgatagc tgggaaggta tccgttacca agttgatcca caaaagatga accggctgta
    57961 agacatccca accaaacaag gttgatagga agatggttaa tacttcagca gtattagcag
    58021 aaagtaggta ctgaatagtc ttttgaatgt ttgagaagac cttacgtcct tcttccactg
    58081 cgacgataat agtcgcaaag ttatcatctg caagaatcat atcagaagcc cccttagaaa
    58141 cctctgtacc agtgattccc ataccgatac cgatatcggc tgttttcaga gctggcgcgt
    58201 cattgacacc gtcacctgtc atggcaacga ctttaccttg tttttgccaa gccttgacga
    58261 tacgaacctt gtgttctgga gacacacggg cataaacaga gtattgacca acgacttttt
    58321 caaattcttc atctgacagt tcattgagtt cagcaccagt taaaacgtga ccttctgtat
    58381 cgtttgcgtc aatgattccc aaacgtttgg caatggcttc cgctgtgtct tggtggtcac
    58441 ctgtaatcat aattggacgg attcccgctt ccttagccac acgaacagcc tcagcggctt
    58501 caggacgttc agggtcaatc atcccaatca aaccagtaaa aattaaatca ttttcaagct
    58561 cttcagaagt gagattttct ggaatactat cgataatctt ataagcacct gcaaggacac
    58621 gcaaggcttg atgagccatt tcagaattgt ttgtatgaat gagatttgta accttctcat
    58681 caatcggagc aatatcccca gccttatcac gaagaagaca acgttttaag agttggtctg
    58741 gcgcaccctt gactgctaca aggaaacgac catctggcaa tgggtgaact gttgacatga
    58801 gcttacggtc agagtcaaat ggcaattcag ctacacgagg atatttctct aagaaacctt
    58861 tgacatcata gcccttgtcc aaggcatatt ggataaaggc tgtttcggtt gggtcaccaa
    58921 tcaagttacc ttccacatcg attttcgtat cattggccaa gacaactgaa cgaagtagtg
    58981 gcatttcaag acctagttca atatcatcag ctgagtcatg tagaaccgca tcgtagaaga
    59041 ctttttcgac tgtcatcttg ttcatagtca gcgtaccagt cttatcagaa gcgatgattt
    59101 cagttgaacc aagtgtttca actgctggca acttacgaac gatggaatgt cgtttggcca
    59161 aaacttgagt accaagagaa agaacgatgg taacgatagc aggaagtcct tctggaatgg
    59221 ctgcaacggc aagggcaaca gaagtcaaca actcaccaag tggatttttc ccttgaatga
    59281 agacacccac tacaaaagta acaagggcaa tgaccaagat agcataggtc aagaccttag
    59341 aaaggttgtt caagttttgt ttgagtggtg tatcagtctc atccgcatct tgaagcatac
    59401 cagcaatatg accaacttca gtgtacatac ctgtattgac aacaacaccc atcccacgac
    59461 cataggttac gtttgagttt tggaaggcca tgttgacacg gtcaccaata ccagcatctg
    59521 tcgcaagctc gactgacaag tctttttcga ctggtacaga ttcacctgtc aaggctgctt
    59581 cttcaatttt aagagagttg gcttctatca aacgtaggtc cgctggtacc acgtcacctg
    59641 cttcaagggc aacgatatcg cctggtacca attctttaga gtcaatctct gccatgtgtc
    59701 catcacgaag aacgcgggca actggactag acatggattt gagggcttca atagcttctt
    59761 cagcttttcc ttcttggtaa acaccaaagg cagcgttgat gataaccaca gctaggatga
    59821 taatggcatc tgcgatatct tccccaccag aagtcacgac tgacaagatt gctgccgcaa
    59881 ctaggatgat aatcatcaaa tccttaaatt gctcgatgaa tttgaccaag attgatcgtt
    59941 tctcgccttc ttcgagttca ttgtgcccaa attcggcaag gcgcttttcc gcctcacttg
    60001 atgacaaacc ttgctcggtc gcatccacag cctgcaagac ctcttcaggg ctctgagtat
    60061 aaaacgcttg gcgtttttgt tcttttgaca tgtgtctcct ccttgacatt gtgtgcaaaa
    60121 cagactctct ttctgtcata tcttttcacg acaaacaaaa agagacctgt taatcataac
    60181 aagtctcgct gtttaagata gggccggaaa gcatactttt cagcataaaa ttcggaatga
    60241 cgacactatc acaggtttct gccagctact cccttgagta gtaccattat accaaatttt
    60301 ggggagtttt caaagagtaa aaactgcctt atttgaattt ttccttgaaa accagtataa
    60361 tggtagaatg ctatgtgact agaaaggaag ttgaatgaag caatctatct caaatctcaa
    60421 gttagctgag cgtggagcca ttatcagtat ttcgacctat ttgatcttgt ctgcagctaa
    60481 attagcagct ggtcatctcc ttcattcatc cagtttggtg gccgatggtt ttaataacgt
    60541 atcggacatc attggaaatg tggccctctt aatcgggatt cggatggcgc gccagcctgc
    60601 agaccgtgac caccgttttg gtcattggaa gattgaagat ttggcaagct tgatcacttc
    60661 tatcatcatg ttctatgtcg gtttcgatgt tctaagagat accattcaaa agattctcag
    60721 tcgggaagaa acggtcattg atcctcttgg tgcaactcta ggaatcattt ctgcagcgat
    60781 tatgtttgtg gtctatctct acaatactcg cctcagtaag aaatccaact ccaaggcgct
    60841 gaaggcagct gctaaggaca atctttctga cgctgttacc tcacttggaa ccgccattgc
    60901 catcctagct agtagtttca attatccgat tgtggataaa ctggttgcta tcatcatcac
    60961 tttctttatc ttgaagactg cctatgatat cttcatcgag tcttccttta gtctttcaga
    61021 tggctttgac gaccgcctgc tcgaggacta ccaaaaggct atcatggaaa ttcccaaaat
    61081 cagcaaggtc aaatcgcaaa gaggtcgcac ctacggtagc aacatctacc tggatattac
    61141 actagagatg aatcctgact tgtctgtttt tgaaagccat gaaatcgcgg atcaggtcga
    61201 gtctatgctg gaggagcgtt ttggcgtctt tgataccgat gtccatatcg aaccagcacc
    61261 tatccctgag gatgaaattt tagacaatgt ctataaaaaa ttgcttatgc gtgaacaatt
    61321 gattgaccaa ggaaaccaac tagaagaact cttgactgat gattttgtct atattcgcca
    61381 agatggagag cagatggata aagaggctta taagaccaaa aaagagttaa attctgctat
    61441 aaaggacatt caaattactt ccatcagtca aaaaaccaaa ctcatctgct atgagttaga
    61501 tggtatcatc cataccagta tctggcgtcg ccacgaaacc tggcaaaata tctttcatca
    61561 agaaaccaaa aaagaataga gaaatccttt catgagacgg gatttttcta ttcttttata
    61621 ctcaataaaa atcaaagtgc aaattaggaa gccggtcaca ggctgtactt gagtcggcaa
    61681 tgtgaagccg acatagtttg cactttgatt ttcgaatagt cttaactatc aaattcactg
    61741 agatactcat agcgttcgta tttttcaagg agtgcttcat ttttctcatc caattctttt
    61801 tggagagtag tcagcttacc aaagtcagag ccgttagcct gcatttcctc ttcaatagca
    61861 gcgatacgtt tttccaaggt ttcaatatca ccttcaatac ttgcccactc ctgcttttct
    61921 tggtaggtca tgcgtttctt gtcttctcga accttgacca ctttttcctt ttcgaccttt
    61981 tgcacttgat tggccatatc tgtttcaaaa gctttttcat caagatagtc ggtgtaatga
    62041 ccaaagaaag gacgaatctt gccatcctca aaagcgagaa tcttggtcgc taccttatcc
    62101 aagaaatagc ggtcgtgact gactgttaaa acgggacctg caaaaccttg caagaaattc
    62161 tctaagactg tcaaagttgc aatatctagg tcattggttg gctcgtctaa aagaagaaca
    62221 tttggttttt ccaaaagcag tttgaggaga taaagacgtt ttttctcacc ccctgacaat
    62281 ttctcaatca aggttccatg cgtcgaacgt gggaaaagga actgctccag caactctgca
    62341 atcgaagtcg tagaaccgcc actggtcttg acctcttctg ccacttcctg caggtaattg
    62401 ataactctct tgctttcatc caaaccctca atttgctgag agaaataggc gatgcgaaca
    62461 gtttccccaa tcacaacttg tcctttagtt ggctcaagac ttcctgcaat caagttgagc
    62521 agggttgatt ttccaacacc attgtcccca acgattccga tacggtcttt ggcctgcacc
    62581 aagagattaa aatcttgcaa aataggcttg ttttcatagg caaaggaaac agcctgaaac
    62641 tcgatgactt tcttcccaat ccgactggtt tcaaagttca tggtcaagtc tgtctcagca
    62701 ctactgcctg aaacttcctt tttcagatca tggaatcgat tgatacgggc ctgctgcttg
    62761 gtcgcacgcg cctgcggttg tctgcgcatc caggccaatt cttgtttgta gagttgttct
    62821 tttttgtgaa gaagagccgc gtcgcgctca tcctgttccg cctttaggcg aacatagtcc
    62881 tggtaatttc cctggtactc ggtcaagcct gctcgctcca actcgaaaat ccgtgttgac
    62941 aaagcgtcta agaaataacg atcgtgagtg ataaaaagga cggtcttctt agaatttttc
    63001 aaaaagaggg tcagccactc aataatcgca atatccagat ggttggtcgg ctcatccaaa
    63061 agcaaaaggt cgtggttgcc aagtaagact tgtgccaact gtacccgtct tctcagacca
    63121 cctgacaatt ccccaacagg agtagataag tcttgaatgc ccaatttgct aagaacggtc
    63181 ttgacctgac tctcgatttc ccaagcttgg agagagtcca tctctgccat gacacgttcc
    63241 aaacgcgcct gcttgtcctc actatagtcg agcataatca attcatactc acgaatgagc
    63301 tggatttcct tgagttcact agatagaacc gtatccaaaa ctgtctttct atcatcaaaa
    63361 tcaggatcct gagtcaagta accaatctgg taatcatttt tagctgaaaa aggactgaca
    63421 tccccatcaa atccagaaac accagaaagg acgtccaaaa gggtggtctt gccagtccca
    63481 ttgacaccga ttaaaccaat tctgtctaag tcatggataa taaaggaaat atccctaaaa
    63541 acggtcttgt caccaacgga tttacttagt ttttcaacga taaaatcact cattttttct
    63601 ccctcaggta agcatggatg gcttcacgat tattctccaa ttctccatcg acaatggcaa
    63661 actcaatctc tgttaaaatc tctcccaagt ctgggcctgg ctgatagcca tattccttga
    63721 tcaaaatacc gccgttgatt tggatttctt tcttatcatg aatagtcaag ctctggtagg
    63781 tttctttaat gacttgtggg ttgacttctt ttccttgagc ttgacgaaga ttttcagcct
    63841 gtaaaagtaa atccaagtca aagcgataac aatcacgctt actcaattct ccattttcac
    63901 gcagagccaa aataatcagc aaatcctgaa cttgcttggc aaactggcgt gaggtcttcc
    63961 aagatttcaa aaatgactgc gcattttcaa tctccaaagc ccatagtaaa gccgcccagg
    64021 cttgttcaga ggattcaaaa gtaaaatcag tctccaaatc aaacagtctg ttgagcttgt
    64081 cctggctaga tgccatatca gggagatagt cataagcttg actctcaatc atggaagcca
    64141 agccccttct ccaaaatgga gccagcaaga gtttatcaaa ctcgacgaag gtacgctcta
    64201 cagaaatttt ctccaaaagc ggcgtcaagg tcttcatagc tttaaatgtt tctggctcaa
    64261 gtgcaaaacc aagactagcc tgaaaacgga aaccacgcat aatccgtaaa gcatcttcgt
    64321 tgaaacgctc actagccact ccaactgctc gcaagacttg cttttccaaa tcttctaaac
    64381 catggaacaa gtcaacgatt tctcctgtct catccaaggc aaaggcgttg actgtgaaat
    64441 cacggcgttt gaggtcttct tctagcgagc gcacaaagga aaccgcactg ggtctgcgat
    64501 agtccacata gacatcctct gtccgaaagg ttgttacctc atactcctca tccccatcta
    64561 agaccaagac ggttccatgc tcgattccga tatcggctgt tcgcggaaaa atctgcttgg
    64621 tctcttctgg ataagaagac gtcgcaatat ccacatcgtg gatagggcta tggagaaggg
    64681 catctcgaac agagccccca acaaaataag cctcaaagcc tgcttcttta attttttcta
    64741 atactggtaa agccttctga aattcagaag gcatttgcat taatctcata ataagtgttc
    64801 taatccatag acaagctcat gacgcttgac aacttcttta attcccaaat tgactcctgt
    64861 catgaaggag atgcgatcat aggagtcatg acggagggtc aacccttctc cctgattgcc
    64921 aaagatgact tcctgatgag ctaccaagcc tggcaaacga actgagtgga tgcgcatacc
    64981 atcaaagtca gcaccacgag caccagcaat cagctcttcc tcatctgctg caccttgctg
    65041 aatggactct cgaacctctg ccatcaactc agctgtttta atggctgttc cactcggagc
    65101 atcctttttc ttgtcatgat ggagctcaat aatctccaca tttgggaaat atttggcagc
    65161 ctgcgtcgca aattgcatga gtaagacagc acccaaggca aagttagggg caatcaggcc
    65221 acccaagtct tgggcacgag aaaattcttt tagctctgca atttcttcac tcgtgaaacc
    65281 agtcgttcca actactggag caaagccatt ttcaagagca aaacgtgtat tttcgtaggc
    65341 aacagctgga gtagtaaaat ctacccagac atccgcttca aaaccagcta aatcagcctt
    65401 atccttgaaa acaggaatac cctgccattc tgactcagac tcaaaaggat ccaaaactgc
    65461 caccaagtcc aagtctggat cagtcaatac catctgacaa gcagcctggc ccatctttcc
    65521 cttaaaaccg gcaataatta ctcgaatact catctctact cctgtctaag atacaaagtc
    65581 cgtaagaaca caaagtgaaa ataggaattc caatcaagaa gtgtctactt cttggaagaa
    65641 ctatcttttt cacacagggt tccaggcgtg ttcaattatc aagatacaaa ggaccttagc
    65701 tgcctctgaa aaatagggaa tggcactgac tttccacgaa aggcaagaca ggcatctttt
    65761 ttcaagaggc aggtagtccg tgttcaattt ctaagataca aggcatctta actagcctag
    65821 aagcgccaac taaatcactg gaatataacc cagagcaata cttcctgctc ctaggtgcgt
    65881 tccaatgaca ctaccaaatg tagcaagtga aacatccgaa cccaagccaa aatcaagcaa
    65941 gtgctgacgc aattcttcag ccttttcagg agcattccca tgaatgacaa tgacccggta
    66001 ttgacctgaa gccgttgttt ccttgataat ttcaattaag cgcttggtgg ccttcttttc
    66061 agtacgaact ttttcgtaaa cttcaatcac accttgatcg ttaaaataaa ggattggctt
    66121 aatgctaagc aaattgccca aaatggcagc cccatttgaa aggcgtccac cttttaccaa
    66181 atgatccaag tcatctacca tgataaaggc tgacgtacgg ctgatttgaa tggctagctt
    66241 atcctgaatg ctggcaaaat catcgccctg atcacgccaa ttaaagacgc tttcaaccat
    66301 gatgcctagg ggagcacttg taatcaaagt gtctgggaaa gcaatggtta agccctcata
    66361 gtcatcgacc atatactgga tattttggta aaaacctgaa attccagaag ataggaaaag
    66421 ccccaaggca tgtgtatagc cttgttcttt gagcgaagtt aagatttcat ctaacttggc
    66481 aatacttggt tgactggtct taggaaattc agaagcctga gccatttttt ggtaaaattc
    66541 ctcagcagac agattgatgc cttcgacata ttcctcacca tcaatattga caggaatatc
    66601 caagacaaac aagtcttctc tttgcaaggt ctctgcactg agataagcag aggaatctgt
    66661 gaaaacagct aatttcatat tagaactcca aattaattcc tggtaagtct aatgcaattt
    66721 cagtcacttc gtaagtcaaa cgattgagca tgttcaaaca tggacgagcc aaggtttcca
    66781 cctcttcttg gttcaattca cttggttcat tgacaatacg gccatcgata tggtttactt
    66841 gtgagattgt tccactaatg acaaacttat caaatacaat cataaagctc aagatgacaa
    66901 tcaaggaagt cacttgattt tcttggtcat gttggagcaa ttggaaattc acatccacct
    66961 tggtttcagg agctccattt tcattttccc attcaaaatt acgcgcatca aaatgatact
    67021 gactaacaaa ttcttgttca cgtttaagat tcatgtcttt ctccatcggc tacaatatta
    67081 taagctattg tatcataatt ttttattttc atctagtttt ctaggattta gtcaatccca
    67141 atttcagcac gaactacatc tgtgatggta tcaacatagt agtctacttc ttctgttgta
    67201 ggcgcttctg ccataacacg caagaggggc tctgttccac ttggacgaac aaggatacgg
    67261 ccgttccccg ccatttcttc ttccatcttc tcgatgatgg ccttgatagc tggcacttcc
    67321 atggcctttt ccttcatgac gttttccact cggatattaa ctaatttttg tggataaatc
    67381 gttacttctg ccgccaactc tgataagctc ttaccagttt ccttcatgat tttagtcaat
    67441 tgaactgctg ataattgacc atcacctgtg gtattgtaat ccatcaagat aacgtgacca
    67501 gactgttcac caccaaggtt gtagcctgat tttctcattt cttcaacaac gtagcggtca
    67561 ccaactgcag taactgcctt gttaatacct tcgcgattca aggccttgtg gaaaccaagg
    67621 ttagacataa cagttgtcac aattgtattt tgagccaatt gtcctttttc agaaaggtat
    67681 tttccgatga tgtacataat cttgtcacca tcgacgatgt caccattctc atcaacagca
    67741 atcaagcggt cactgtctcc atcaaaggcc aaaccaatag ctgacccact ttctttgacc
    67801 acttcttgaa gggcttctgg atgtgttgaa ccaacattaa ggttgatgtt aagaccgtct
    67861 ggtgtttccc cgataaccgt caattgggca ccaaggtctg caaagatttg acgggcactg
    67921 gtagaagctg ctccattagc tgtatccaag gcaaccttca ttccatcaag aggagttcca
    67981 gttgaaacaa gatatccttc atacttacgc aagccttctg gataatctac caagattcct
    68041 aagccttctg cacttggacg aggaagagtg tcttcctcag catctagcaa ggcttcaatt
    68101 tctgcttctt tttcatcatc tagtttgaag ccatcaccgc caaagaactt gattccgtta
    68161 tcaagggctg ggttgtggct agcagaaatc atgacaccgg cacttgctcc ttcagtttca
    68221 accaagtaag ctactgctgg tgttgcaagg acaccaagtt tgtatacgtg aatccctact
    68281 gaaaggagac ctgccaccaa ggccgattcc agcatttccc ctgaaatacg tgtgtcacgt
    68341 cctacaaaga ctttcggcgc ttccgtttca tgttgactaa gaacatagcc tccaaaacgt
    68401 cctagtttaa aggctaattc tggtgttagt tctaggttag cttctccacg gactccatca
    68461 gtcccaaaat atttacccat tgttataaaa tccttttcta tttttaattc gtttttgaac
    68521 tagttgcttt cgttgacgaa gatgtctccg atgaactgct tgtacttgaa tttgatgtgc
    68581 ttgaacttgg tgctactggt tttgtagtca ccttcattat tgtatcaaac ggagtgataa
    68641 ctgccggtaa gacaacacca ttgcggtcga ttgcctgcaa aggtactgaa ccactgtaat
    68701 tacctgttat acgttcgcta gttggcaaga cagcgataat cttatcaatt ctatccaatg
    68761 tctcttggtc actcgtaata gacacttctt tatctgacac catgacattt tcaatttgta
    68821 cccgactatc aatttgacta gggtcaatct ctggtacaat ctttacctta tccttctgag
    68881 ccttcttacc aatcttgact gtaatttttt gcggagtcgc cacagcggtc agcccattgg
    68941 gtaaatcttc aatgctcaaa ggaacttcaa tcgttccaac accggcatct gttaggtcag
    69001 cagtaacctt gaatttacgt gtactttctt gcatttcact agctagcgat aggcgatttg
    69061 caccagtcaa gaccactgat acttctgaag caaaaccgct aataaaatac ttatcactat
    69121 tatagcgtat gtcaataggg acatttgtta ctgtattagt ataggtttcc gtttttacct
    69181 gcctagcact ggtactgttt tgaaaattcg tcgccgtagc atagacaaat aagacacaag
    69241 caaaaaagag tgaggatatg atatataaac tatttttttt catgtttcca tcctcctagc
    69301 aatcgttctt taaaactaag acccacttcc tcttttggaa gtaagatttc acgtaattct
    69361 gtttcaaatt catcaagtgt taggttgtgc ttaaaccttc cattataggt tatcgaaatt
    69421 cctcccgttt cctctgatac gacaaaagtc aaggcatctg agacttctga taaaccgata
    69481 gccgcccggt gtctggtccc aaattccttg gaaatccctg tgttttttgt caagggcaga
    69541 taggcagacg tcacagcgat acgttcttct ttgataatca ccgcaccatc atgtagggga
    69601 gtgttgggaa taaaaatgtt aatgagaagt tctgcagaaa tcttagcatc caagggaatt
    69661 cctgtcgaaa tatactcctg caaggtacgt acacgctgaa tagcaaccaa ggccccgatt
    69721 ttacgaggac tcatgtattc aacagactta acaaaggcac gaatcatctg ttcctcagca
    69781 ctaatagggg cattggaaaa aaaatctgtc gctcttccca aacgttccaa accagtccga
    69841 atctctggag agaagataac aaccgccgca ataaccccat aagtaataat ttgattgatt
    69901 aaccaagaaa tcgtagtcaa accaatcata tttgcaagga tttgagctaa aataaacacc
    69961 aaaactccac gtaccaaaat cataatcttg gttcctgcaa tagcttttgt aaaatggtat
    70021 aaaatataag caacaatcaa aatatcaatc agattgatag ctatcgtcca tggacttgca
    70081 aacaaactgg tccaatattg cagattggat aattgttgaa aattcatccc tgatatcctc
    70141 cctatcaaaa cactttcgtc ctattatacc attttctggc atttttttcc ctatcctagt
    70201 ccattttaca ttgaacaaaa atatgataaa ataaactgac tagaaaaaac aaaggagaaa
    70261 ctatgtctca actctatgat attaccattg tgggtggtgg tcctgtcggg ctttttgcag
    70321 ccttttatgc ccacctacgc caagccaagg ttcaaatcat cgactctctt ccccagctag
    70381 gtggacaacc tgctattctc taccctgaaa aggaaatcct agacgtacca ggcttcccaa
    70441 acctgactgg agaagagttg actaaccgct tgattgaaca gctaaatgga tttgataccc
    70501 ctattcatct caatgaaacg gttcttgaga ttgacaaaca agaagaagaa tttgccatca
    70561 caacttctaa aggaagtcac ctgactaaaa cagttatcat cgctatgggt ggcggtgcct
    70621 tcaaaccacg tccgctggaa cttgaaagtg ttgagggcta tgaaaatatc cactaccacg
    70681 tttctaacat tcagcaatac gctggtaaga aagtgacgat tcttggcggg ggagactcgg
    70741 ctgtggattg gactttggct tttgaaaaaa tcgcaccaac tacccttgtt caccgcagag
    70801 ataatttccg tgccttggaa cacagtgttc aagccttgca agaatcatct gtaaccatca
    70861 agacaccatt cgtccctagc caactccttg gagatggaaa aacgcttgat aaacttgaaa
    70921 tcacaaaagt caaatctgat gaaactgaaa ccattgacct agaccacctc tttgtcaact
    70981 atggtttcaa atcttctgtc ggtaacctta aaaactgggg gctcgacctc aaccgtcaca
    71041 agattatcgt caacagcaaa caagaatcca gccaagcagg tatctatgct atcggtgact
    71101 gctgctacta tgacggaaaa attgatctga ttgcgacagg tctaggggaa gctccaactg
    71161 ctgtcaacaa cgctatcaac tacattgacc ctgaacaaaa agtacaacca aaacactcta
    71221 ccagtttata aaaaagaacc acgagtcaca taggattcgt ggttttataa ttcatccgca
    71281 tttaaaaata cctttacatc gttttactat atcttacaat accttttaaa acagctatat
    71341 tttgagcttt taaataaatg tttttacatc attttacaga gatttacgac acttttgccc
    71401 cttttttgcc ccttttttaa aacaaaaaaa ccgcaagcct gagcctgcgg tgaaagaaca
    71461 atttagaaag tttcctttct atttatttaa ctgtaatcaa gccatctggc tctactgtga
    71521 agtctggctt atctgccagt gttccgtctg gtttgaggta gtaccagcct gttccgtctg
    71581 cggactggac gaaggcgttt gataccatag caccttcttt agcgtctaag tagtaccaag
    71641 tgttcttgta cttgacccag cctgtcttca tggcaccttc tacatcaaaa tagtaccact
    71701 tctcagcgat tttcttccag cctgtggcca tttcgcctga ttggtcaaag tagtaccaat
    71761 taccgtctgt gtgcttcttc cagcggtctg aaagcatata gcctgagcca tcgaaataat
    71821 accaggtacc gttgattttc tcaaacttat cttttggata agagccgtct gagtgtacgt
    71881 accagtagcc agtgccattt ttctgccagc ctgttgcagc tctcaagccg ttttcgatgt
    71941 cttgcttaaa ctgttcacgg ctaatgcccc atttagcaag atatggatat ggatccacat
    72001 ggtctgagtg gttgtttggt tggttattgg tacagtattc atgcgtcttg atacctgcca
    72061 agtcgtctgt atcaagagtc ttcggcaagc ctgcttcgtc cgctagattg cgtagcaatt
    72121 cgatatagag gcggtagtcc gtcatgaact cttctttagt tgaatggctt tcaatcagtt
    72181 caaccgctgc gtaactctca gcattccaac cgcccccaac atcccaactt ccgttgttca
    72241 caggtcctac ctgcatgatg cgaccgttcc caacaacgtg cgagaaaaaa cctaattctg
    72301 ggtctttccg ccagtgataa tccgcttcat tctgtacggt tgagttacgg ttgcctgttg
    72361 aatgggcgtg tacttgtcga taaggctgca ccccaacctg tggcaagcct gtacgtagtc
    72421 tgtttctatc gatatccatt ccctatcgtc ctttccatgc gtcattcatc tgcttcactg
    72481 ctgactctac gaaggtgtct aagtctttgt cagtcatgct aatattgtat tttgtaagct
    72541 cagcacggac tttagcgcga gcctgtgcca gtttttcatc tcccttgtag ccagtttcag
    72601 cagctacttg ctcaacggca tttactgcat ttttggccaa gatttcaacg attttgatgg
    72661 tcttttctcc acctttttga accaggtagt ccttgactgc cttgactgcg ataccagcca
    72721 aaataacaag gatgctgatt gctccattag taatgatttc agtaatttgt tgcatttgtt
    72781 attctccttt ttcgatttct tccatgcggt cgttcatgcg aaccatttct ttttgaatgt
    72841 ctccgaccgc gtgagtgatt gtggttaatt ctgtagtggt cttttctagg tgagtcatca
    72901 aacgctcttc tcgtctatta gagtcggcct ttgattgctc gtgcaaatcc ataatcttct
    72961 tctctcgctt gtccgaagtc ttgataagat atcgaatgat aataaagaaa agcaagataa
    73021 acaaaatcgc ccaagctacc tgactttgag cgattttttc agcttcttca attggcatac
    73081 acacctccta ttctttaggt tttaccgttg gatccgtcca gtcaggattg ccctctgcat
    73141 caaatttcat gatatagaat tcatgattca acagaacggc gacgttgatt gttgcgattg
    73201 taccacccca ctggttgaac gcccaaacgg tttcaacatc cttgagttgg cgacggccat
    73261 ttacgatcac aggacgtttt tgaacatcac gatacatata gaagtcatcg cttacattct
    73321 tgcaacgaat gaactctcca ttttctttca tgtagcgcaa agcactcgca agatcaaatg
    73381 gttctgtgat ttttgtaagg tctagtaagt tatctgtgtt ttgatttgtt tctgccatgt
    73441 ctattctcct ttgtctgctg gtttagtttg ttcatcaagc agagcttcca gctcatccac
    73501 tcgtgcttga agtctttgat tcccttccct ttgctcatcc aactgaatac tcaagatatt
    73561 atttgtaatc atcgaatttg ttgaagttgt tgacatttca ctaattgtca tttgtaaggc
    73621 ttggttaagc tgttctgtgt tcattttcta agttctccaa tctgtgtgtt cgttttctat
    73681 tttcaagagc aagctcctga attgctttaa agtgcgatat tggtcaacat gttgttattc
    73741 atgctattgt tttctccatt ttttctattt tttgatttaa ttcttgaata gccttgatta
    73801 agtaaggaac taaagcggta tagtcaatat gcagatagcc atctggattc tcaggatctc
    73861 gtgagacaat tcttggaacg atggtttcag cctcttgagc tattagacca atctcctcat
    73921 gttt
//
LOCUS       DAVLBN010000002        69001 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLBN010000002 DAVLBN010000000
VERSION     DAVLBN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.002"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..225
                     /locus_tag="VXC24_000077"
     CDS             <1..225
                     /locus_tag="VXC24_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492267.1"
                     /translation="DKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGQ
                     WYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(704..853)
                     /gene="rpmG"
                     /locus_tag="VXC24_000078"
     CDS             complement(704..853)
                     /gene="rpmG"
                     /locus_tag="VXC24_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0492268.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(869..1051)
                     /gene="rpmF"
                     /locus_tag="VXC24_000079"
     CDS             complement(869..1051)
                     /gene="rpmF"
                     /locus_tag="VXC24_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0492269.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1203..1403)
                     /locus_tag="VXC24_000080"
     CDS             complement(1203..1403)
                     /locus_tag="VXC24_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0492270.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1406..2413)
                     /locus_tag="VXC24_000081"
     CDS             complement(1406..2413)
                     /locus_tag="VXC24_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0492271.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2604..4634
                     /locus_tag="VXC24_000082"
     CDS             2604..4634
                     /locus_tag="VXC24_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0492272.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4638..4922
                     /locus_tag="VXC24_000083"
     CDS             4638..4922
                     /locus_tag="VXC24_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0492273.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4935..6281
                     /locus_tag="VXC24_000084"
     CDS             4935..6281
                     /locus_tag="VXC24_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0492274.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            6285..7142
                     /locus_tag="VXC24_000085"
     CDS             6285..7142
                     /locus_tag="VXC24_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0492275.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7139..8071
                     /locus_tag="VXC24_000086"
     CDS             7139..8071
                     /locus_tag="VXC24_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0492276.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8304..10007
                     /gene="ilvD"
                     /locus_tag="VXC24_000087"
     CDS             8304..10007
                     /gene="ilvD"
                     /locus_tag="VXC24_000087"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0492277.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10168..10248)
                     /locus_tag="VXC24_000088"
                     /pseudo
     CDS             complement(10168..10248)
                     /locus_tag="VXC24_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10306..10647)
                     /locus_tag="VXC24_000089"
     CDS             complement(10306..10647)
                     /locus_tag="VXC24_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0492278.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10771..11622
                     /gene="rgg"
                     /locus_tag="VXC24_000090"
     CDS             10771..11622
                     /gene="rgg"
                     /locus_tag="VXC24_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0492279.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11815..13062
                     /locus_tag="VXC24_000091"
     CDS             11815..13062
                     /locus_tag="VXC24_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0492280.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13140..14429
                     /locus_tag="VXC24_000092"
     CDS             13140..14429
                     /locus_tag="VXC24_000092"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0492281.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14420..14500
                     /locus_tag="VXC24_000093"
                     /pseudo
     CDS             14420..14500
                     /locus_tag="VXC24_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14770..15084
                     /locus_tag="VXC24_000094"
     CDS             14770..15084
                     /locus_tag="VXC24_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492282.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15094..15300
                     /locus_tag="VXC24_000095"
     CDS             15094..15300
                     /locus_tag="VXC24_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0492283.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15300..15497
                     /locus_tag="VXC24_000096"
     CDS             15300..15497
                     /locus_tag="VXC24_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492284.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15500..16234
                     /locus_tag="VXC24_000097"
     CDS             15500..16234
                     /locus_tag="VXC24_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0492285.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16246..16887
                     /locus_tag="VXC24_000098"
     CDS             16246..16887
                     /locus_tag="VXC24_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0492286.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16905..17135
                     /locus_tag="VXC24_000099"
     CDS             16905..17135
                     /locus_tag="VXC24_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492287.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17487..19250
                     /gene="aspS"
                     /locus_tag="VXC24_000100"
     CDS             17487..19250
                     /gene="aspS"
                     /locus_tag="VXC24_000100"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0492288.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19228..20169
                     /locus_tag="VXC24_000101"
     CDS             19228..20169
                     /locus_tag="VXC24_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0492289.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20379..20459)
                     /locus_tag="VXC24_000102"
                     /pseudo
     CDS             complement(20379..20459)
                     /locus_tag="VXC24_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20595..21581)
                     /locus_tag="VXC24_000103"
     CDS             complement(20595..21581)
                     /locus_tag="VXC24_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0492290.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21591..22391)
                     /locus_tag="VXC24_000104"
     CDS             complement(21591..22391)
                     /locus_tag="VXC24_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0492291.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22652..23494)
                     /locus_tag="VXC24_000105"
     CDS             complement(22652..23494)
                     /locus_tag="VXC24_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0492292.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23496..24788)
                     /locus_tag="VXC24_000106"
     CDS             complement(23496..24788)
                     /locus_tag="VXC24_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0492293.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24899..26170)
                     /locus_tag="VXC24_000107"
     CDS             complement(24899..26170)
                     /locus_tag="VXC24_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0492294.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26720..28237
                     /gene="malQ"
                     /locus_tag="VXC24_000108"
     CDS             26720..28237
                     /gene="malQ"
                     /locus_tag="VXC24_000108"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0492295.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28263..30521
                     /gene="glgP"
                     /locus_tag="VXC24_000109"
     CDS             28263..30521
                     /gene="glgP"
                     /locus_tag="VXC24_000109"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0492296.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31566..32138)
                     /locus_tag="VXC24_000110"
     CDS             complement(31566..32138)
                     /locus_tag="VXC24_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492297.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32761..33609)
                     /locus_tag="VXC24_000111"
     CDS             complement(32761..33609)
                     /locus_tag="VXC24_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0492298.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33761..34039
                     /locus_tag="VXC24_000112"
     CDS             33761..34039
                     /locus_tag="VXC24_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492299.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34041..36104
                     /locus_tag="VXC24_000113"
     CDS             34041..36104
                     /locus_tag="VXC24_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0492300.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36182..37438)
                     /locus_tag="VXC24_000114"
     CDS             complement(36182..37438)
                     /locus_tag="VXC24_000114"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0492301.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37580..40045
                     /locus_tag="VXC24_000115"
     CDS             37580..40045
                     /locus_tag="VXC24_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0492302.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            40110..41021
                     /locus_tag="VXC24_000116"
     CDS             40110..41021
                     /locus_tag="VXC24_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0492303.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41251..41949
                     /gene="dapD"
                     /locus_tag="VXC24_000117"
     CDS             41251..41949
                     /gene="dapD"
                     /locus_tag="VXC24_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0492304.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            42017..43147
                     /locus_tag="VXC24_000118"
     CDS             42017..43147
                     /locus_tag="VXC24_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0492305.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43159..43698
                     /locus_tag="VXC24_000119"
     CDS             43159..43698
                     /locus_tag="VXC24_000119"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0492306.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43682..44359
                     /locus_tag="VXC24_000120"
     CDS             43682..44359
                     /locus_tag="VXC24_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0492307.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44431..45330)
                     /gene="galU"
                     /locus_tag="VXC24_000121"
     CDS             complement(44431..45330)
                     /gene="galU"
                     /locus_tag="VXC24_000121"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0492308.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45352..46368)
                     /locus_tag="VXC24_000122"
     CDS             complement(45352..46368)
                     /locus_tag="VXC24_000122"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0492309.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46590..46993
                     /locus_tag="VXC24_000123"
                     /pseudo
     CDS             46590..46993
                     /locus_tag="VXC24_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(47108..47533)
                     /locus_tag="VXC24_000124"
     CDS             complement(47108..47533)
                     /locus_tag="VXC24_000124"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492310.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47601..48251)
                     /gene="phoU"
                     /locus_tag="VXC24_000125"
     CDS             complement(47601..48251)
                     /gene="phoU"
                     /locus_tag="VXC24_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0492311.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48266..49018)
                     /gene="pstB"
                     /locus_tag="VXC24_000126"
     CDS             complement(48266..49018)
                     /gene="pstB"
                     /locus_tag="VXC24_000126"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0492312.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(49020..49835)
                     /gene="pstA"
                     /locus_tag="VXC24_000127"
     CDS             complement(49020..49835)
                     /gene="pstA"
                     /locus_tag="VXC24_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0492313.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49828..50691)
                     /gene="pstC"
                     /locus_tag="VXC24_000128"
     CDS             complement(49828..50691)
                     /gene="pstC"
                     /locus_tag="VXC24_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0492314.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50809..51684)
                     /locus_tag="VXC24_000129"
     CDS             complement(50809..51684)
                     /locus_tag="VXC24_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0492315.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51851..53182)
                     /locus_tag="VXC24_000130"
     CDS             complement(51851..53182)
                     /locus_tag="VXC24_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0492316.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53183..53890)
                     /locus_tag="VXC24_000131"
     CDS             complement(53183..53890)
                     /locus_tag="VXC24_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492317.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53974..54276)
                     /locus_tag="VXC24_000132"
     CDS             complement(53974..54276)
                     /locus_tag="VXC24_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0492318.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54263..54484)
                     /locus_tag="VXC24_000133"
     CDS             complement(54263..54484)
                     /locus_tag="VXC24_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0492319.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54446..55004
                     /locus_tag="VXC24_000134"
                     /pseudo
     CDS             54446..55004
                     /locus_tag="VXC24_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55319..57010)
                     /locus_tag="VXC24_000135"
     CDS             complement(55319..57010)
                     /locus_tag="VXC24_000135"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0492320.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57146..57592
                     /gene="argR"
                     /locus_tag="VXC24_000136"
     CDS             57146..57592
                     /gene="argR"
                     /locus_tag="VXC24_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0492321.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57643..60177
                     /gene="mutS"
                     /locus_tag="VXC24_000137"
     CDS             57643..60177
                     /gene="mutS"
                     /locus_tag="VXC24_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0492322.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60324..62018
                     /gene="patA"
                     /locus_tag="VXC24_000138"
     CDS             60324..62018
                     /gene="patA"
                     /locus_tag="VXC24_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0492323.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62349..62618)
                     /locus_tag="VXC24_000139"
                     /pseudo
     CDS             complement(62349..62618)
                     /locus_tag="VXC24_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62810..64576
                     /gene="patB"
                     /locus_tag="VXC24_000140"
     CDS             62810..64576
                     /gene="patB"
                     /locus_tag="VXC24_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0492324.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64715..65404
                     /locus_tag="VXC24_000141"
     CDS             64715..65404
                     /locus_tag="VXC24_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0492325.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65408..65587
                     /locus_tag="VXC24_000142"
     CDS             65408..65587
                     /locus_tag="VXC24_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492326.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65574..66923
                     /locus_tag="VXC24_000143"
     CDS             65574..66923
                     /locus_tag="VXC24_000143"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0492327.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            67047..68507
                     /locus_tag="VXC24_000144"
     CDS             67047..68507
                     /locus_tag="VXC24_000144"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0492328.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68521..68955
                     /locus_tag="VXC24_000145"
     CDS             68521..68955
                     /locus_tag="VXC24_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0492329.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20237 a        12832 c        14924 g        21008 t
ORIGIN      
        1 gacaaaggct tatggtatta cttaaacgaa tcaggttcaa tggctactgg ttgggttaaa
       61 gacaaaggct tatggtatta cttaaatgaa tcaggttcaa tggctactgg ttggtttaca
      121 gtttctggtc aatggtacta tacctataat tcaggagatt tattagtaaa cacgactaca
      181 cccgatggct atcgagtcaa tgctaacggt gagtgggtag gataggtatc cattagctaa
      241 atctaatcat tctgaactaa aaaatcttct tacatatgta ggaagatttt ttggattctc
      301 aaaactagtt taaaagacta cgctatttaa accaatttta agaatggata tataaggata
      361 ttcagaaatc tagttggtca acttttgtat tttgaatata ccttagatgg tgacgatgtc
      421 ttggtatatc tggtactcac ttacatattc taacttattt taactaagat acaactgtag
      481 ttggtgaatt tgctacaaat agtgtagagg cgttatttga aaaatataca aaaaaggaac
      541 cccaacttac atttgagttc ctcttgcttt taattgtccg aatccgtatt cttatttcaa
      601 taatgtagtc attcgaatga tttcccttgc aatatagtga aattaacaaa aagaaaaaac
      661 gctgatcaag cgtttttctt ctgtattgat tcgtattgaa tgcttacttc acttctgtaa
      721 acacaacgtg tttgcgaagt tttggtgagt atttcttcaa ttgaaggcgg tctggagtgt
      781 tacgtttgtt tttagaagta aggtacaagc gttcaccaga ttctttgtgt tcaagtgtaa
      841 tatttacgcg catagtatct cccttctatt attcagctga tgcagcttta gcgattttac
      901 gtcctttgta gtatccttta agtgatacac ggtgagaacg tgagtaatct ccagtagttt
      961 cgtcaaagtt tacagatgga gctgttactt tgtagtgtgt acgacgtttg tttttcttcg
     1021 cttttgaagt gcgacgtgca ggtactgcca ttttgatttc tcctttaggt atttatattc
     1081 gattcaatct actgattttc atcaaccata ctaggataac acattttttt tgtaaagtaa
     1141 agttacttga caaaaaaaga tgaaaaaatt ctcctatccg acacggcaga caggagaagg
     1201 tgttaaatat caatctcaaa tggttcgtca atggtttctg atacgtattt tccgtctttt
     1261 ttccgttgct tgacacactc tgtgaggaga tattctattt gcccattgac tgaacgaaag
     1321 tcgtcttctg cccatgatgc gagtgcagcg tataactttg ttgagagtcg aagggggatc
     1381 tgcttttttt tagcttcagc catctttagt aaagacttcc tgtgttgaca attggttgtg
     1441 catcatgatt gccacaaaga acgacaagga gatttgaaac catggcagct tttcgttctt
     1501 cgtcaagttc taccaattcc ccttcattga gccgttctag tgccatttca accattccta
     1561 cagcaccatc tacaatcatc ttacgtgcat caataatggc agatgcttgt tggcgttgaa
     1621 gcataacggc agcaatttct ggagcataag ctaggtaagt gatacgtgct tcaaggattt
     1681 ccaagccagc atcctcaaca cgactttgga tttcttcacg aatacggtta gcaacaattt
     1741 cgctagagcc acggagacta ccttcatctg cttgcccgtc acccgtagta tccacattag
     1801 gagacacatc gtaaggatag atgcggacaa tattacggag ggcgctatca cattgcaatg
     1861 aaagatattc tttgtagtta tcaacgttga agactgcctt agcggtatcg acaactctcc
     1921 aagttaccgc gataccgatt tctacagggt ttcctaagca atcattgatt ttttgacgag
     1981 aattgctcaa ggtcatgact ttgagggaaa tctgtttctt gccaatttca agatttacat
     2041 cattgtcatt tgatgattta gctcctaaaa aaggagattt tgtgctaaca tcaccacttt
     2101 gtccaagtcg agtgtggttt gcagggttga ctgctacgct gaagggattg acaaagtaaa
     2161 aaccaggttc tttgatggta cctgtataat taccaaagag tgtcagaacc agagcttcct
     2221 gaggtttgac aacttttaaa ccagcatgag ctagacctgc aattacgatt agtaaaggtc
     2281 cgataataat tccaaaaatg ttttccgaac caacacccat tataaatata aagataccaa
     2341 gtacgattgt caattcaatg agaatcaatg cgaatacacc atttggtttt gaattgatga
     2401 gtttttcagt cataagaatg acctcctatt atttgatatc taaatgatat cactttgttt
     2461 ttaaaagtca atagaaagtt gaaaataatc actaaaaagt ttcagcccaa taatttcttt
     2521 taaaaggtga gattatattg tgctcaaata ctcttttatt cttataattt ttacactata
     2581 attgtagtta gaaaggaaga gaaatgtttg attatagagc actagttatt ttgatgactt
     2641 tgatggatca ttgtgagcta tcattatatg aattatctgt taaggtgagc ttacctataa
     2701 aggaagtcaa agaaggaata gattatttag tgccttatct agctaataaa gggatagtgc
     2761 tggataaaaa acaaggtcgc tatagtttat caaatcgtac gaagcagtct ttgacagata
     2821 ttattaagtc ggatgaattg gttttaccaa agtcgactcg cttagcttta atctatcttt
     2881 acactttttg ccgattagat tttatatcga ataatcatta ccaagacttt ttgaaagtaa
     2941 gtaagaatac aaccttatct gatattcaat cattaagaaa gattatgtta gataatgatt
     3001 tggagctagg gtacagtaga gcaaaaggtt atactttaca cggttcagag tggaataagc
     3061 accgcttagc ttttcaaatg gttagtgagt tgctggaatc ctccataggg atttggggtt
     3121 tggattatgt tttatccagt tgggggtatt cattaactta tgatttgata aatcaggtag
     3181 ttaaagatta ttatgagaag ctacagctag tacctattgt taatcaatta aaagtttgcc
     3241 ttttcggttt agtattcatt ctgtgtaggt atcaaaggga tgttgaaaga gtatgtcttt
     3301 cagagacatt agtatctcct gttattcaag atataacgac tattttattg gatacagtgg
     3361 ttgatttggg aattatagat acggtgtttt ctgaggatga ttatcgctat atcaccgttt
     3421 tattatcaag ttgctttgaa ggtgaagtag atgttgctcc ggtttacttt aatcaattaa
     3481 cagaggctat tataagtaga atggaagata tttctttgtt acattttaaa caaagggaag
     3541 gattgagaga aaatcttcgc cgccacctta taccggctta ctatagatta aagttcggcc
     3601 tacctagttc aaatgaatat gtattgcatg ttaaagaaca ttatcctgat ttatttgaat
     3661 tagtcaaaga ttctttgatg cccttgatgg acgctattga caatcccata cctgatagtg
     3721 aaacagcata ttttgttatc catttcggag gttatttaaa gaaagcagat actttgcctc
     3781 aaaaatgcta taaagcagca atcatttgtc ctaatggtgt tagttcttca ttgatgttaa
     3841 aagagaatct attagcatta tttcctcaaa ttgagtttat aggaacctca aagattgatg
     3901 atttacaggt gaaagctagt agtgactatg atatggtttt ttctaccata aaggtggaga
     3961 cagaaaagcc aaattatcta gtttcggtta tgatgactga agagcaagca atacaactag
     4021 tagaactagt gttaaaagat tttccgaatt tagagtatgg ggattttgag attgaacaaa
     4081 tcctgaatat tgtcaaaaga tatggaatta ttacacaaga attggaatta agattggcgt
     4141 taaagaatta tctttaccaa aaaaatgata gaaaggaaat tgtaccagtg ctagaacaac
     4201 tcattaccaa agaaacctat caggttagtt cgcaaaaatt aggatggaag gaggcgattc
     4261 gtttagcagc taaaccgctt ttggatcaag ataagataac tgagaactac cctgaggcaa
     4321 tgattcaaaa agtagaagag tttgggcctt ttattaattt agggaaggga gtagcaattc
     4381 ctcacgctcg gccagatgaa ggtgtgaatg aaataggaat gtcaatgtta gttttggaag
     4441 aaccgattta tttattggat aatccagaac aagaggtaag attgttgatt tgtattgcag
     4501 ccattgataa tgagagtcat ttaaaggctt tgtcacattt aacaacaatt ttaagagata
     4561 aaaatcatgt tcaaacttta atatcatcaa aaaactatga tgacattaaa atgataatta
     4621 aacaggagga ttagataatg ttaaaaattg gtacagcttg tggttcagga ttaggttcaa
     4681 gttttatggt acagatgaat attgaatctg tattgagtga tttgaatgtt tcggatgtag
     4741 aagttgaaca ttatgattta ggtggagcag atccaaatgc agctgatatt tggattgttg
     4801 gtcgtgatct agctgattca gctagtcatc ttggagatgt tcgtatctta aatagtatta
     4861 ttgatatgga tgaactacga gaattaatta ctaaactttg tgaagaaaaa ggacttatat
     4921 aggaggctag cgttatgatg aagttcatat tggatattgt tagtacacca gctattttag
     4981 tagctttaat tgcaatttta ggattagttc ttcagaagaa gaaattacct gatattatta
     5041 aaggtggaat taagaccttt gttggtttct tagttgtatc tggtggtgca ggaattgtac
     5101 aaaattcttt aaatccattt ggtaccatgt ttgagcatgc ttttcattta tctggcgttg
     5161 tgccgaataa tgaagcaatt gtagctgtag ctttaacaac atatggctca gctactgcac
     5221 tgattatgtt tgcaggcatg gtgttcaata tcttaatcgc tcgttttact cgatttaaat
     5281 atattttttt aacagggcac cacactctat atatggcatg tatgattgcg gtcattttat
     5341 cagttgctgg ctttactagc ttgcctctta tcttactagg aggattagca ctcggtatta
     5401 ttatgagtat ttccccagca tttgttcaaa aatatatggt tcaattaact ggaaatgaca
     5461 aggtggcttt aggtcatttc agttctttgg gatattggtt gagtggtttt actggtagcc
     5521 ttatcggtga caaatcaaaa tcaacagagg acattaaatt tccaaagagt ttagcttttt
     5581 tacgtgatag tactgttagt atcactttat ccatggcagt tatttacatt attgtagcta
     5641 tctttgcagg gtcagaatat atagaaaaag aaatcagtag tggtacaagt ggtctagttt
     5701 atgctttaca attagcaggt caatttgcag caggggtatt tgttatttta gcaggtgttc
     5761 gccttatttt gggcgaaatt gttccagcct ttaaaggtat ttcagagcgt cttgtaccta
     5821 attcaaaacc tgctttggat tgtccgattg tttatactta tgcacccaat gcagttctaa
     5881 ttggatttat ctctagtttt gttggtggtt tagtaagtat ggcaattatg attgcttcag
     5941 gaacggttgt tatcttacca ggtgttgtgc ctcatttctt ctgtggagcg actgcaggtg
     6001 tcattgggaa tgcatctggt ggtgttcgtg gagccactat tggagcattt ttacaaggta
     6061 ttttaatcag ttttcttcca gtctttttaa tgccagtttt gggaggactt ggtttccaag
     6121 gatcaacttt ctcagatgca gattttggtc tatcaggaat tattttagga atgttaaatc
     6181 aatttggctc acaagcaggc attgtgattg gtcttgttct tattctagca gttatgtttg
     6241 gagtatcctt tattacaaag ccatctgcaa aggaggaata agggatgatt ttaagtaaaa
     6301 atagggaaga tgagttaaga aaatttgcga ctaacatccg attaaatact cttagaacat
     6361 tgaatcatct tggattcgga cattacggag gaagtctgtc tatcgtagaa gttttagcag
     6421 tgctttatgg tgaaataatg ccaatgactc cagaaatatt tgcagcacga gatagagatt
     6481 atttcatatt atcaaaaggt cacggaggac cagctctata cagtacactc tatttgaatg
     6541 gtttctttga caaagaattc ttatattctt taaatacaaa tggaaccaaa ttaccgtctc
     6601 atcctgatag aaatctaacg ccaggcatag atatgacaac gggctcttta ggacaaggaa
     6661 ttagtgttgc aactggactt gcatatggtc agagaataag aaagagtccc ttttatactt
     6721 atgctattgt tggagatggt gagttaaatg agggacaatg ttgggaggct atacagtttg
     6781 cttctcatca acagttatcc aacttaattg tatttgttga tgataacaaa aaacaattag
     6841 atggttttac aaaggatatt tgtaatccag gtgatttcgt agaaaaattt tcagcatttg
     6901 gatttgaatc cattagggtc aagggttcag atattagaga aatttatgaa gggattgtcc
     6961 aattaaaaca gtcaaataat tcatcaccta agtgcattgt attagatact attaaaggtc
     7021 aaggggttca agagctggaa gaaatgaaat ccaaccatca tcttcgccct actgtagagg
     7081 agagacaaat gttaacttca gttgtagaaa gattaagtca ggaattggag gaaacagaat
     7141 gatgagaagc acgaaagaat tacggcatgt atatagagac ttccttttag aggctaatca
     7201 aagttattct gatatagtag tcttagaagc cgatttgtca agttcgatgg ctactaataa
     7261 tcttgaaaag gattttggag accgttatgt gaatgttggg attatggaag cagaaatggt
     7321 cggccttgca gcaggcttgt ctattcaggg gtttagacct tatcttcata catttggtcc
     7381 ttttgcttca cgaagagtat ttgatcaatt atttatttct cttggatacg cacaattgga
     7441 tgccactgtg attggatcag atgcaggagt aactgcagaa atgaatggtg ggacacatat
     7501 gccatttgaa gaaattggat tgttacgttt aattcctaaa tcgatcattt ttgaagcaac
     7561 tgatgatatc caatttcgtg aaatattgaa ccagacatta gacttaaaag gactaaaata
     7621 tattcgaaca attagaaaag ctccagttcc tgtgtatcaa ggtggagaag atttttctaa
     7681 gggctacatt gagttaaggc atggtgaaga tcttgtaatc gttgcttctg gtataatggt
     7741 tgctccaagt attcgagttg cagatgaact gtctaaatta ggttattcag taagtgtgat
     7801 agatttattt agaatcaaac cgataccaga acagataaaa acaatgttaa gtggaaaaac
     7861 tatatttact gtagaaaacc acaatcagat aggtggaatt ggcagttctt tatgtgaatt
     7921 attctctgat gatggaatga caaaaattca tcggatgggt gttcaagaaa gattcggtca
     7981 agtagggaaa atggattatc ttcttaatga gtatggtttg agtgaatcga atataaaaga
     8041 gaaggttcta gaaatttata atgcaagata gatgttaaat acacttatct gaaagaattt
     8101 ctgtaaaaat tacagtacgt tatttaaaga aagcggatta aaaagcatat tctggtcatc
     8161 agaaagtgca ctaatccgct ttgttgtttt taattttaaa tatttcacat gtgtatagaa
     8221 ttttctgaaa attcaagatt tttattctgt tcttcatgcg aaaattgtgc tataatagta
     8281 aaaactgaaa tgggagggat aagatgactg aattagataa acgtcaccgc agtagcattt
     8341 atgacagcat ggttaaatca cctaaccgtg ctatgcttcg tgcgactggt atgacagata
     8401 aggactttga aacaccgatt gtgggagtga tttcgacttg ggcggaaaat acaccatgta
     8461 acattcactt gcatgatttc gggaaactgg ctaaagaagg tgtcaaatct gcaggcgctt
     8521 ggcctgtaca gtttggaacc attaccgtag cagacgggat cgctatggga acgcctggta
     8581 tgcgtttctc tctaacatct cgtgacatca tcgcggactc catcgaggcg gctatgagtg
     8641 gtcacaacgt ggatgccttt gtcgctatcg gtggctgtga caagaacatg cctggatcta
     8701 tgattgctat tgctaatatg gatatcccag ctattttcgc ctatggtgga actattgcac
     8761 cgggaaatct tgatggtaaa gatatcgact tggtttctgt ctttgaaggt atcggaaaat
     8821 ggaaccacgg tgacatgaca gctgaggacg tgaaacgtct tgaatgtaat gcctgccctg
     8881 gccctggtgg ctgtggtggt atgtatactg ctaataccat ggcaactgct atcgaagttc
     8941 tagggatgag tttgccaggg tcatcctctc acccagctga atcagctgat aagaaagaag
     9001 atatcgaagc agcaggacgt gctgttgtta agatgttgga acttggtctc aaaccatcag
     9061 atatcttgac tcgtgaagcc tttgaagatg ctattactgt aacgatggct ctcggtggtt
     9121 ctacaaacgc cactcttcac ttgctcgcca ttgcccatgc cgcaaatgtt gacttgtcac
     9181 ttgaggactt caatacgatt caagaacgtg tgcctcactt ggccgacttg aaaccatctg
     9241 gtcagtatgt cttccaagac ctctacgaag tcggtggtgt ccctgcggtt atgaagtact
     9301 tgttggcaaa tggtttcctt cacggagatc gcatcacatg tactggtaag actgtagctg
     9361 aaaacttggc tgactttgca gacttgactc caggccaaaa agttatcatg ccacttgaaa
     9421 atccaaaacg tgcggatggt ccgcttatca tcttgaacgg gaaccttgct cctgacggtg
     9481 cagttgccaa ggtatcaggt gttaaagtgc gtcgtcacgt tgggccagct aaggtctttg
     9541 actcagaaga agatgcgatt caggccgttc tgacagatga aatcgttgat ggcgatgtag
     9601 tcgttgttcg ttttgttgga cctaaaggtg gtcctggtat gcctgagatg ctgtcacttt
     9661 cttcaatgat tgttggtaaa ggtcagggag ataaggtggc cctcttgacg gacggacgtt
     9721 tctctggtgg tacttatggt ctggttgttg gacatatcgc tcctgaagct caggatggtg
     9781 gaccaattgc ctatctccgt accggcgata tcgttacggt tgaccaagat accaaagaaa
     9841 tttccatggc cgtatccgaa gaagaacttg aaaaacgcaa ggcagaaaca accttgccac
     9901 cactttacag ccgtggtgtc ctcggtaaat atgcccacat cgtatcatct gcttcacgcg
     9961 gagccgtgac agacttctgg aatatggaca agtcaggtaa aaaataaact catactcgaa
    10021 aatctcttca aatcacgtca acgtcgcctt gccgtaggta tggttactga cttcgtcagt
    10081 tctatccaca acctcaaaac agtgttttgg gctgacttcg tcagttctat ccacaacctc
    10141 aaaacagtgt tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga
    10201 gcaacctgcg gctagttttc tagtttgccc tttgattttc attgagtatc aaaaagcaag
    10261 ccattttcgg cttgcttttt tcatctttaa aagtgattgg cctgcttaac gaggtggtag
    10321 tccaagggca atacggccat agcgactgat tcgtgtgatt ttccaagcag gcgaccaggt
    10381 aacttcaacc ttgatatctt tgataccctc gatttgtttc agacctgcca caatttcaat
    10441 aggcaggctt tcggcgcaat cacaggcagt atcggtgaag gtcatgacaa tcttgcagag
    10501 ccccgtttca tccagattga tttcataaat cagacctaga ttgtaaacat ccaattccac
    10561 atctgtatca aaaactttct ctagtttttc gataatttgg tcttgcaagg ccaaagcacg
    10621 gtcattgatt ttgatatcgt ctctcatagc agtccctcca cgtgataaat atcctctatt
    10681 ttctcataat tctgacaatt tggcaagttt ttgatgaatt ttctgaaaaa taggataaaa
    10741 tgaagaaaat acggaatcaa ggggaagtct atggagcaga ttggaaaagt ctttagacaa
    10801 ttacgagagt caagaaatat ctcactgaga caagcaaccg gaggacaatt ttcgccgtct
    10861 atgttgtccc gttttgaaac aggtcagagt gagctttcgg tggaaaagtt tctatttgct
    10921 ctggaaaata tatctgccag tgtggaggag atcctctttc tggcgagagg tttccagtat
    10981 gatacagatt ctgagttgag aaaagaaatt acagatgtct tggaaccaaa gaatatagca
    11041 cctcttgagg acttatatcg cagggagtat caaaagcatg cccattctca caacaaacag
    11101 aaacatattc taaatgccat tattatcaag tcttatatga agagcatgga tgaaagggta
    11161 gagttaacag cagaggaagg aaaagtcctt catgattatt tgttttctac cgagatctgg
    11221 ggaatctatg aactcaattt attttcagtc agttctccat ttttatctgt ttctcttttt
    11281 actagatatg tacgagaaat ggtacgtaaa tctgattttc taatggaaat gtctggcaat
    11341 cgaaaccttt ttcatactat actattgaat ggctttttag ctagtattga gtgtgaagaa
    11401 tttaccaatg cctattattt taaacgtgtt atcgaagagc atttctacaa ggaaaatgag
    11461 acctatttcc gaattgttta tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga
    11521 gtcaaggaag gccagaaaaa gatggaggat gctgtccgta tttttgagat gcttggctgt
    11581 aataaatctg ccgaatacta tagaaatacg accgaatgtt gaatatctgc aaaccaagaa
    11641 aaaatttgaa gcgatagaac tattgccctc tctcaggtca ttacaaaagt tctatcgttt
    11701 ctttttgctc attttatttg ttgcatatat tcaagagttc tccctctcaa atttctaagt
    11761 gctatactat agtcatactt catatagagg ttcgaacaag aagggagatt atctatgaaa
    11821 ctattgttta gaaatccagc ttatagaatt ttgattttat cacgcttctt caatgctttt
    11881 ggtgcttcga ttttcaacct ggtctttatc gtctatgcat cgaccttgtc acaagcatct
    11941 tttgctgttg ctatggcgaa tattgtcatg attcttccga ccctctttac agtttttgta
    12001 gggattcggg cagattacac gagggacaag gtcaaatgga tggtctatag cggtttgttt
    12061 caggcggttc tattttttct agcagcccta gttgttcagc aagctagtct ctttgccttt
    12121 tctagcctgt gtttgatcaa tgtcattagt gatatcatca gtgattttgc aggtggcctg
    12181 cgtatgcctc ttattaagga aaaagtagct gaagatgatt tgatggaggc ttattctttt
    12241 tcacagttca tcacctatat ttcagctatt ggtggtcaag ctttcggagt ctggctctta
    12301 gctctatcgg tcaacaattt ttctctcgtt gcgggaatca atgcctgctt tttcctagta
    12361 tcagccacta tcctcttttt aggaaaaagc aaattgagcc tgtcaatgtc atctgctgat
    12421 ggtgaaaact taaaaaatga gaagctttct atcaaagacc agttcctaac aatttaccga
    12481 aatttacgtc tcgtttttct taaaagtggg cagaaaaact ttggttttat gctctttgct
    12541 gtcttgctta ttaattcctt gggtggcgct ttgggtggaa tttataatat cttctttttg
    12601 agccattctc tcttgaattt ttcttataca gaggcactat ttatcaatca attctgtgtt
    12661 ttagtagcaa tcatcatcag tagccttacg ggcaatgatt attttgggaa gcagtccttg
    12721 cctagattga tgatgtgggc gaccgtagga cttagtctag ttggtttggc taatttattc
    12781 aatcaagtcg tgcttggttt gctatttctc ttctttaccc tgtatgtgtc tggtaaagtt
    12841 caaccaaaga ttagtgccat gctcatgaaa aatctagctc cagaggttct agctcgtact
    12901 agtaattttt taggtctatt gtttacctta tccatacctg tgggaacagc ttgtttttca
    12961 ctagtagccg tatggaatat acagttgact tggatgctat ttgttggtct ttccttgcta
    13021 gctatttttt tgacaattct taatctcaaa aatgatatct aaatcctaat ttttttctta
    13081 ctgttttaat ccctttattt gtggtaaaat aagactatta agtttaaaga ggattcccta
    13141 tgaaattaca aaaaccaaaa ggaacgcagg atattttacc tgctgaatct gctaagtggc
    13201 agtacgttga gggctttgcc cgtgagattt tcaagcgcta taactatgca gaagtgcgca
    13261 cgcctatttt tgagcattac gaggttatca gtcgctctgt cggagataca acggatatcg
    13321 taaccaagga aatgtacgat ttttatgaca agggtgaccg tcatattacc ctccgtccag
    13381 aaggaactgc gcccgttgtc cgttcctatg tggaaaataa actcttcgcc ccagaagtgc
    13441 aaaagccaag caagttctac tatatgggac ctatgttccg ttatgagcgt ccacaggcag
    13501 ggcgcttgcg ccaattccac caaattggtg ttgagtgttt tggctctagc aatccagcta
    13561 ccgatgtgga aacaatcgct atggcagccc attttttgaa ggaaatcggt attcaaggtg
    13621 tcaaattgca cctcaacact cttggaaatc ctgagagccg tgcagcctac cgccaagcct
    13681 tgattgacta tttgacaccg ctcaaggaga ccttgtctaa ggatagccaa cgtcgcttgg
    13741 aggaaaatcc tcttcgtgtc ttggactcta aggaaaaaga agacaaggag gcagtagaga
    13801 atgcgccgtc tatcttggac tttcttgatg aagaaagcca agctcatttt gatgctgtgc
    13861 gtcagatgtt ggaaaatctt ggagtagatt acatcatcga taccaatatg gtgcgtggtc
    13921 tggactacta caaccacacc attttcgagt ttatcacaga gattgagggc aatgacctga
    13981 ccgtctgtgc gggtggtcgt tacgatggtt tggtttctta ttttggaggc cctgaaactg
    14041 ctggatttgg ttttggactt ggtgtagagc gcctgcttct cattcttgaa aagcaaggtg
    14101 tgaccctccc tatcgaaaac gccctagatg tctatatcgc agtcttgggc gaaggggcaa
    14161 atatcaaggc cttggaattg gtacaggctc ttcgccaaca aggtttcaaa gcagagcgtg
    14221 attacctcaa ccgtaaacta aaagctcagt tcaagtcagc cgatgtcttt gtggctaaga
    14281 ccctcatcac cctaggagag agcgaagtcg aaagcggaca agtgacggtc aagaacaacc
    14341 aaactcgaga agaagtgcaa gtgtcacttg agacaatcag ccaaaacttc tcagaaatct
    14401 ttgaaaaact aggattttat actcaataaa aatcaaagag caaactagga agctagccgc
    14461 aggttgctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca
    14521 tggttttgag gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggtgaa
    14581 gctgacgtgg tttgaagaga ttttcgaaga gtattaatga tagataaagt ggtcaggaac
    14641 ttactcctga cctttttctt ttgcaaaatg acaaaaatca taaacttttt gacaaatata
    14701 cttgtcaaaa agaaaaagat atgttacaat gaattcaagt taagaaatag gaagcagaaa
    14761 ggagttataa tgtgggtact aggatttata ctatttatga ttttctttta ttctaataat
    14821 tctaaaaaaa tcaagaaact agagaataaa atcaaaaaac ttgagcgaaa agagaaagga
    14881 aacgcagaaa tgtcgagatt attacaagaa atgattggaa aggaaccaat tataacggga
    14941 gtgtatattg ggccagataa ctgggaagtt gtggatgttg atgaggaatg ggtcaaacta
    15001 cgtagtgttg ataatacggg aaaagaaaaa ttcaagttgc aacgtattga agatatccaa
    15061 accgttgaat ttgacggaga gtaggtgtgt aacgtgcaac taaaaaatcg tctaaaagag
    15121 cttcgagctc gcgatggtct caatcaaacc gacctagcca aactggcagg ggtttccaga
    15181 cagaccatta gcctactaga acgggatgag tacaccccat ccattatcat tgccctgaaa
    15241 atatctcaaa ttttcaacga aacagtcgaa tcggtatttc gtttggagga ggacgagtga
    15301 tgaacaagta taaagtgatt tattatgtag tggtcatagc tttattagtc agcgtatttc
    15361 tactgattgg gatggaccta agctggttta atccctatca aggcgaccaa tttgtttggc
    15421 tctactttgc tctcatccca gtaattgaat ggattgaaaa gaaatccaaa aatctagcaa
    15481 gtgaaaaagg agaatgaata tgaaaaagaa acgtagattg ttatttttga tgtctattgt
    15541 cttggggggg ttcttgggca tgtttgtagg gatgtttaag gcacgtgtcg aatcccacga
    15601 aattatttta gatgtaaaag ccttgatgcc atggatatca gctatttgtt tactgatagg
    15661 tttcattagt atgtttttga ctttcaattt cttaaagaaa agcagaaaat ttcattcctt
    15721 gtatcaagag gaaatggatg acgatctgaa tgaaacctat tatgtgcaaa tgtatcggaa
    15781 tcttgagttt ggaaccattg cttttaatat tacaggtgta gcgattccat tggctatttt
    15841 tatttcatta agtgaggtga ttatattgca tacaaaccct caaacatttt tcctttcttt
    15901 cttactcttt gtggtattct tagtcgctca aaaatctctt tttaaaacca ttgcgattgt
    15961 tcgtcagttt gatttggaat ttttcgctac accaaaggat gtcttgaact atataaattc
    16021 ttatgatgaa ggggagcgtc aggctaattt ggaacagagt tttcgaattt tattccaatt
    16081 acaccaatat gtcttaccag ccttatatat ttttcttatt atcatttctt tcttgacagg
    16141 agagattcag ttactagctt tcttgcttgt aggagccatc catgtttata tcaatgtgat
    16201 gcagttacct atggtaaaac gttatttcaa ataaaggagt tatctatgaa attacttaaa
    16261 aaccttggct ggattcttct agcccttcta tcctttttat ttatctatgg ctttattcag
    16321 gggctcgcga ctgcgtcgct tgctttaggc gcttcaccct atgctgttac tctactctat
    16381 gtggccttgg ctggagtata tgtgtacggc atttacaaat ggtatcagaa ggctcctgtt
    16441 catattgaga agagcggctt taaccgattt atttggcttc ctgccttggt ttggttctta
    16501 tctctggtcg ttcaattctt cttgccagat gatccttcag taaatcagca aatagcgaca
    16561 gacttgacct tgtctcaacc acttttctca ttctttgctg tggttatttt tgctcctttg
    16621 acggaagaga ttgtttttag agggatgtta gcacgctatc tctttcctaa gcaggacaat
    16681 agtaaacgaa ccctgatttt tcttctggta tctagtcttc tatttgcctt gattcatttt
    16741 ccaggtgatg tgcaacaatt ttttgtctat tttagccttg gttttagttt gggcttggct
    16801 tacattagca gaaaaggtct ggtctacagt atttctcttc acgctttgaa taatttagtc
    16861 ggctttttga tgattctcat gctataatag agtcaggagg tcacatgaaa cgagtaattt
    16921 tattagcagt gattcaggca gtcgttctat ttttcatcat tggagcgcta gcttatgcct
    16981 tcaaaggcga tttcttctat aactatctag cagttgtctt tgctcctatt gcaggtgtac
    17041 tgcgttttgg gacggcttac ataacggaaa ttgtcttgcc tcgaaaggca gccgaaatcg
    17101 ctgaaaagcg taaagcaggc aaaaattcaa aataaaagag tccggtgaag ttcatcggat
    17161 ttttgtatta tactcaatga aaatcaaaga gtaaactagg aagctagccg caggttgctc
    17221 aaaacactgt tttgaggttg tagatgaaac tgacgaagtc agctcaaaac atggttttga
    17281 ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggtaaggcga cgctgacgtg
    17341 gtttgaagag attttcgaag agtattagcg ctaattttta gggctttcac ttgactttta
    17401 aagactggca aacttttctg atgattttca tgaagagcct gcgcttttat ggtaaaatag
    17461 taacagaata aaagaggaga gaaataatga aacgtagtat gtatgctggt cgtgttcgtg
    17521 aggaacacat cggacaagaa ataaccttga aaggatgggt tggccgtcgt cgtgaccttg
    17581 gtggtttgat ctttatcgat cttcgtgacc gtgaaggaat catgcagttg gttatcaacc
    17641 ctgaaaaagt atctgcagag gttatggcaa cagctgaaag ccttcgtagc gaatttgtta
    17701 ttgaggtgac tggtcaggtc gctgcgcgtg agcaagccaa tgataagttg ccaactggtg
    17761 cggttgagtt aaacgtgaca gctcttattg tgcttaacac agctaagaca acaccatttg
    17821 agattaagga tggcattgag gcaaatgacg atacacgttt gcgttaccgt taccttgacc
    17881 ttcgtcgtcc agaaatgttg gaaaatctta aacttcgtgc caaggtgacc cactctatcc
    17941 gcaactattt ggatgagttg gagtttatcg acgtggagac accattcctt tctaagtcaa
    18001 cgcctgaagg ggcgcgtgat tatttagtgc cgtctcgtgt taataagggg catttttacg
    18061 ctcttcctca aagtccacaa atcacgaaac agctcttgat gaatgctggt tttgaccgtt
    18121 actaccaaat cgttaaatgt ttccgtgacg aggacttgcg tggagaccgc cagcctgaat
    18181 ttactcaggt cgacttggaa acgtccttcc ttactgagaa agaaatccaa gatattacag
    18241 aaggcttgat cgcgcgcgtg atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc
    18301 ctcgtatgaa atacgatgat gctatggctc tttacggttc tgacaagcca gatactcgtt
    18361 ttgacatgtt gcttcaggac ttgacagaag tggtcaaagg tgtagacttt aaagtctttt
    18421 cagaagcacc tgctgtaaaa gcgattgtgg tcaaaggagc tgcggacaac tattcacgta
    18481 aagacatcga caagatgacg gaagtagcca aacagtatgg tgccaaaggt cttgcttggg
    18541 tcaaggtggt tgatggagaa ttaaacggac cagttgccaa gttcttgact ggtatccaag
    18601 aagaattgac aacagcgctt gctcttgaag ataaggactt ggttctcttt gtggcggata
    18661 cgcttgaagt ggctaatgca acactgggtg cccttcgtgg acgtattgct aaagagcttg
    18721 gcttgattga taatgataag ttcaacttcc tttgggtggt tgactggccg atgtttgaat
    18781 ggtctgaaga agaaggccgc tacatgagcg cccaccatcc attcacactt ccacaggaag
    18841 agactgctca cgaattagaa ggtgatttgg ctaaggttcg tgccattgct tacgatatcg
    18901 tcttgaacgg ttatgagctt ggtggtggta gccttcgtat caaccaaaaa gaccttcaag
    18961 aacgcatgtt caaggctctt ggtttctcaa ctgaagaagc caatgaccag tttggtttcc
    19021 ttcttgaagc catggactat ggtttcccac cacacggtgg tttggctatc gggcttgacc
    19081 gttttgtcat gttgcttgct ggagaagaaa atatccgtga agtcattgcc tttcctaaga
    19141 acaacaaggc aactgaccca atgacacaag ctccatcaac agtcgctctc aaacaactag
    19201 aggaactcag cttacaagta gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc
    19261 tattatctgc gccgctttgc ttatcagata aaaattttac gtgtcttaca aagtatctct
    19321 cgagaaaagt atgatgagaa gatttcggcc tctctggtct atggtttttt atcagcagta
    19381 gcagttaatt tctttttcca accagggcat gtgtattcga gtggtgcaac aggtctggca
    19441 cagattatct ctgccttgag taatcactgg tttggttttc atattccgat ttcgctaagc
    19501 ttctacgcca ttaacttccc tttgatggtc ttagcttggt atcagattgg ccataagttc
    19561 accgtcttta cctttatcac ggtatctatg agttccttct ttatccagtt tgtccctgtg
    19621 gcaaccttga cggaggatcc cattatcaat tccctttttg ggggtgttgt tatgggtttg
    19681 gggattggtt ttgctcttcg aaacaatatc tccagtggtg ggacggatat cgtcagcctg
    19741 actattcgca agaaaacggg taagaatgtc ggtagtattt ctttcttggt aaatggaact
    19801 atcatgctga tagcaggttt gacctttggt tggaaatacg ctctttattc tatgattacc
    19861 atctttgtct ctagccgtgt gacagacgca gtctttacta agcaaaagcg tatgcaggcc
    19921 atgattgtga caaatcatcc agagaaggta attgaaaaaa tccataaaaa attgcaccgc
    19981 ggagcaacca tgatccacga tgcagaagga acctataatc acgagagaaa ggcagtttta
    20041 atcactgtca ttacacgtgc agagtttaat gaatttaaac agattatgac acaagtggat
    20101 ccaagctcct ttgtctctgt ctcggaaaac gttcatattc taggaagatt tgttgagata
    20161 gataattagt gattaatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc
    20221 gtatatatgt tactgacttc gtcagttcta tctgcaacct caaaaccatg ttttgagctg
    20281 acttcgtcag ttctatctgc aacctcaaaa ccatgttttg agctgacttc gtcagtttca
    20341 tctacaacct caaaaccatg ttttgagctg acttcgtcag ttctatccac aacctcaaaa
    20401 cagtgttttg agcaacctgc ggctagcttc ctagtttgca ctttgatttt cattgagtat
    20461 aaaaagatct tgggaaaaga ctcaatttca gtagaaaagg aagtaaatct tcccacaata
    20521 aaacgcatag tatcaagttt tttcaatacc tgatagtatg cgtttttgct tttaacgact
    20581 ctttgcccag tctcttattt ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt
    20641 tgtttattgt ttttattatc attaataatc tggagaatag tttcaaggga aacacgacca
    20701 agctctaaac tattgatatc gacataggct gccaagttga gcttgggatt aaccgagtca
    20761 aagctgagaa cagggacatc cagctggtgt ttggcaatat agttacaaac accttcagct
    20821 aggaggctat cggttgtgat gatagcatca atttgtggat cgtgcttgaa taatcgcttg
    20881 ctaaatttat agcccttttc ttccagaaac tcgtcggcaa agtagatgcg attgttgtca
    20941 gtggtaagtt tgtaatgttt aagcgcctgt tcatagcccg ttaaacggtc tttggtcacg
    21001 aagagctttt tacttcctcc gataaaggca atgcgtttgc agcctttttt gatgaaatat
    21061 tcagtcgcat caaaaccagc ttgaacattg tcgttgtcga caagtgggat gaaaggagat
    21121 agagatttac ctaagataag gaaggggaac tgttcttctg cgacgagttt tacgagaggg
    21181 tcttcttctt gggcatagag aaagattagc ccatctacac gcttgccgta gaccatttgt
    21241 gaaatagcgt tgagacgctc cttctcatct ttccctgttg ctatttgaat ggcatagtgg
    21301 ttttcagatg cgacttgaga gatgccacgt agaaccgatg gaaagaaagg attctggtag
    21361 aaggcgtctg agtcatcagg aagaactaat ccgataacct gagtatagct gcttaccaag
    21421 ctacgagcgt taaggtttgg gtggtagttg agttccttca tagctttgcg aacgcgtttt
    21481 tttgtttcgt cgctaatggt tgatttattt tgaataacac gggttacggt tgaaggcgaa
    21541 acaccagcag ccttggccac gtctttaatc gtaacgggca taaaaatctc ctatttatgg
    21601 taatttggat cacggaaatg tgttttataa aagatagtga ccagatacag aacaaaaaga
    21661 atattttgta cagtaatcag ggttgtcata ttttggccaa ataatcccaa aataagtgta
    21721 atcagagtcg gcaatcctaa acagttcaag ataaagtgat agcactcttt aaaggttcta
    21781 aatgaaaaga ggcgtgattt cttagtgata taaaggagaa gactagctcc tagagagacg
    21841 ataaagaaat tcaaaccaaa gaggaagctc gcaccgagaa ctaggaagag gctgatatag
    21901 acacgatttt gttggtacca gtctttagaa attgcttggg tcaagctgtc tttgcttttg
    21961 aaactctcag tctgaatggc tcggtaagag atgcgggtca gttccttgct ttccttgctg
    22021 atgactagtt catttgtatc gaaatgcagt tgcaagtcct taggtaattc cttgatttga
    22081 cctggaccaa tcacaacaga aggggcttga ctagctgttc cagtataagt taatgtgcca
    22141 tcgacaattg tagcatgttc agagagatcc tggacaacct catttgtcag aggttcatag
    22201 acattatcga taaaagtttc tagcggatag gtctcctggg agctgttttg gatagcaatg
    22261 ggtaccatag acaagctgat aaggaagata ctggtaaaga gaagttgaaa ccagttgagc
    22321 tcgaaacgtt tggacagggg cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga
    22381 tatggaagca taggtatctt tctaaaaggt gttttctata tgagtattat tatatagaga
    22441 aatgcgcttt atttcaagtc tagggggtaa attgcttgct acaaggatat tatttacagt
    22501 gacaatcgct aatagtcaat gaaaatcaaa gtgcaaacca ggaagctagc tgcaggttgc
    22561 tcaaagcaca actttgaggt tggagataaa gctgacgtgg cttgaagaga ttttcgaaga
    22621 gtataaaatg aaaaagggtg gcggggataa attatccctt gtcgccacca cttgtaagtc
    22681 ctgaaacaaa gttcttttgt aggaagaaga agagaataca gattggaagg gcgatgagga
    22741 tagcacctgc tgagaagtag gcaatcttca agtttttcgc attgttaacg aaggtttgga
    22801 gacctacggc aacagtaaag tattctttct cacgaagcaa gaaactagag aggatgtagt
    22861 ccccgaaagg tcccatgaag gcccagagag cttgtacggc aaccattggg cgaacaagtg
    22921 gtagaacaat ttgccagaag cggcggaagt gtcctgcacc gtctagtttt gcagattcgt
    22981 ctaaagacat tggcactgta tcgaagtagc ctttcatgag ccaagcattc atcgggatac
    23041 caccaccaac gtagaggaag atgaggaacc agttgtggtt aagggcgttc aacataagcg
    23101 ccataacgaa gaaggctgtc aaagcggcca tagttggcac catttggatg atcaagaaga
    23161 agaccaaact ttgtttacga gccaagaagt tgtaacggct gtaagcataa ccagcaagta
    23221 cgatgatact tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg ttgaggtacc
    23281 aagtaccgta caaggtttca gtgaagaggc ctttaaagtt atcaaaattg aggtcgatat
    23341 tagtatctag tttaaaggct gagacgttac ctgctttaaa ggctgacatg atggtaatca
    23401 acagtggata gataattaca attgatagac caatcaggta aaggtaagta aggctttgag
    23461 tcagtctacg tttgagttta attgagttat tcatcttaga cgtcctccat atcaaatgcg
    23521 tgtagtttct tgaatgcgat catagagatt gagatgacaa tgatagagat aatcaaggta
    23581 acagctgccg ccattgagta ttgaggagat gtacctgttg tcaaacggta gatccatgag
    23641 atcaagatat cggttgaacc agctccacct ccgacactac caggtcctcc accattgaag
    23701 aggtacatga tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa agtaggtgcc
    23761 gcaacagcca aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc gttggcaccg
    23821 tcaatataag ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc caaagtcaaa
    23881 acgtagatgt atgggaatcc gagccaacct tgcatcataa tcaaggcaat cttagtccaa
    23941 gttgggtctg ttttccaagg aataagagct ccatcaagga aaggaaggaa tttagccaag
    24001 attggcaata cttgagtgtt gatagcaccg acactatcgt taaacatgtt tgagaatgtc
    24061 aagatagtga tgaaggctgg gacagcccaa ggaagaagga aaataacacc aaagatacgt
    24121 tttcctttga taaatggttg gttggcaatg atagctgtga agataccaat tacgatttgt
    24181 aaagtagaag ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc aaaggcagaa
    24241 cggaaggtac tcaagctcca aatgtttgta aagttggtca aaccaaccca gtccaacaac
    24301 ttgtttggtg gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa ggttacgata
    24361 actgggaaga taatcgcgaa ggtcatggca acataagatg gaatgatcaa gaggtaaggg
    24421 aagccatttt cataaatccc tttgatcatg tctttgagtg tgcgtggaac tggaattcca
    24481 ttgttaatgc gttttgcaat cgtatgtgca tctttgatat ttgagaaata aaagagtaca
    24541 taaacgatta caaagattag atggaaggca ccacgaatca gcataaagag ggaattatca
    24601 cgacctggtt tgtcaccaag agtgatgagg ttgctcaatt caggggttgc aagtgctagg
    24661 aagtaaagga caaatacgat ggttacacca aggaagataa aacctttggc tttttgttta
    24721 ttgtaaatct gtcctaaccc aggaatgata gacagcaggg ctgctttact aggttgttgc
    24781 ttttccatat taactccttt cataggatac tactttttta taagaaagct aaattatttg
    24841 tgtctctatt gataaattca aagggggatt tgatttccac cccccttgaa caaatttttt
    24901 attcaccaaa tttttgtttg attgtttctt tgatcaatgt tacagcatcg ttagcagctg
    24961 ttttagcatc tttttgacca cttacagcat caaagagcat atttttcgct ggatcccaaa
    25021 ctgcagacat ttgagagatg tttggcagtg gttgagtgtt cttgaactgt ttgataacag
    25081 ctgttgtcaa ctcatcgttt ttaccttcag cgtatgaacg agcctcagta ttagctggga
    25141 tttcgttagt cttatcatat aatacttttt gttgttcagt tgcaacaagg aagtctacaa
    25201 atttttgaga agcttcaagg ttcttaacgg cttgaggaat gacccaagct ttaccaccac
    25261 cgaatgcagc atattctttt ccatttggaa gagttgggat agttgcaact ccgtagttta
    25321 ctttagcatc tttaaaggct tgagctttcc aaggtccgtc gatgatagca gctgttttac
    25381 cttcttggaa ttgagtttgg attaagtttc cagcaccttc tgtatcttgc atacctttag
    25441 gccatttttc gtaccaagat ttagcgtagt tgatacctgc gatagaaccg tcgtttgcaa
    25501 gaccgatgtc tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg ttaccggcaa
    25561 gaagtccata tgtatagtag aagtttgtcc agtcagctag gaaggcagta gttttaccat
    25621 cttcaccagc gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca gcaaatgttt
    25681 ttggagcatc tttcaccaag tctttgttgt agtacataac aagtgactcg ataacggcag
    25741 gagcaccgta aactttacca ttagcagctg ttacaagaga tttagttgtg tcgtctgttt
    25801 tagcaccatc gctcaatttc acttctgaaa gttgtccgtc agaaccaagg ctacctacac
    25861 ggtcgtatgg agccatcata acatcaggga cattaccaga ttggttgtca agagaaagtt
    25921 tatcaagacc tcctagagca tcaccagttt taagagtgac ttttactcca gcttcttttt
    25981 cataagcttt agcaacctct tcaatatagc tcttatatcc ctcgtctaca tatacagtga
    26041 gttctttgac ttcagatgaa ccagaatcag caggcttatc agcagttttg cttccgcaag
    26101 ctaccaaaag caagctagca agtgtagcag ttccaagcac cgcagtgctc ttcataaatt
    26161 tagatgacat agtgtattcc tcccaaagaa tagcaagttt tattgataag gaaacgcaaa
    26221 cgttttcctt tatgagctta gtatagcaca aatagaaaac ggttgcaagt attttttgta
    26281 aaaattttaa aaaattttta agcttgattt gatagcataa ttttgcattt taatagaaga
    26341 aaagtatgaa atagataaga atacagtatt tttaataaaa atatatggaa tctgtctaaa
    26401 gagggaaatc aggaggggct acctccctgt ttctaatccc tatctatttt ctatagacgt
    26461 ttgtgctttg ttgcatataa attcaagctc cctaaggagg ttttgtactt tgtagactgt
    26521 ctcgtgagag tcaaacttta ggattagata gttttaagtt atctttgcta aaatgagtta
    26581 gtctccttaa aaataatcaa aaaagttttt taaaaacgct tgcaattatg cttgaaaagg
    26641 agtatactta taagtaacgc aaacgtttgc gtctgcaaaa tacgcaacgt tccattattt
    26701 taacacacga ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc acatctcttc
    26761 tcttccagga gcttacggaa tcggatcatt tggtcaaagt gcttacgact tcgttgattt
    26821 cttggtccgt acaaaacaac gttactggca aatccttcca ttaggagcaa ctagttacgg
    26881 ggattctcct taccaatctt tctcagcctt cgcaggaaac actcatttta tcgatttaga
    26941 tatcttggtg gagcaaggtt tgttggaagc aagtgacctt gaaggagttg actttggtag
    27001 cgatgcgtct gaagttgact atgctaaaat ctactatgca cgtcgtcctc ttttagaaaa
    27061 agcggtgaaa cgtttctttg aagtcggaga tgttaaagat tttgagaaat ttgctcaaga
    27121 caaccaatca tggcttgagc tctttgctga gtatatggct atcaaagagt attttgacaa
    27181 tcttgcttgg actgaatggc cagatgcaga tgctcgtgct cgtaaagctt cagcacttga
    27241 aagctatcgt gagcaattgg cagacaagtt ggtttaccac cgtgtgactc aatacttctt
    27301 cttccaacaa tggttgaaat tgaaagctta cgctaacgac aaccacatcg aaatcgttgg
    27361 ggacatgcca atctacgtag cggaagattc aagtgatatg tgggcaaatc cacatctctt
    27421 caaaacagat gtcaatggta aggctacttg tatcgcagga tgcccaccag atgagttttc
    27481 tgtaactggt cagctttggg gtaatccaat ctatgactgg gaagcaatgg acaaagacgg
    27541 ctacaaatgg tggattgaac gcttgcgtga aagcttcaaa atctacgata tcgttcgtat
    27601 cgaccacttc cgtggcttcg aatcttactg ggaaatccct gctggttccg atacagcagc
    27661 acctggtgag tgggtgaaag gtccaggcta caagcttttt gcagccgtta aggaagaact
    27721 tggtgagcta aacatcatcg cagaagacct tggcttcatg acagatgaag tgatcgaatt
    27781 gcgtgaacgt actggcttcc caggaatgaa gattcttcaa tttgccttca acccagaaga
    27841 cgaaagcatt gatagcccac acttggcacc tgctaactca gttatgtaca caggaacaca
    27901 cgataacaat acggttcttg gttggtaccg taatgagatt gatgatgcga ctcgtgagta
    27961 catggctcgt tacacgaacc gtaaagaata cgaaacagtg gtacacgcta tgcttcgtac
    28021 agtattttca tcagttagct ttatggcaat tgcaactatg caagatttac tagaattgga
    28081 tgaggcagct cgtatgaact tcccatctac ccttggtgga aactggtctt ggcgtatgac
    28141 tgaagatcaa ttgacaccag ctgtcgagga aggtttgctt gacttgacaa caatttatcg
    28201 ccgaattaat gaaaatttgg tagatttaaa gaaataagac aataatcagg agacaactaa
    28261 acatgttatc actacaagaa tttgtacaaa atcgttacaa taaaaccatt gcagaatgta
    28321 gcaatgaaga gctttacctt gctcttctta actacagcaa gcttgcaagc agccaaaaac
    28381 cagtcaacac tggtaagaaa aaagtttact acatctcagc tgagttcttg attggtaaac
    28441 tcttgtcaaa caacttgatt aaccttggtc tttacgacga tgttaaaaaa gaacttgcag
    28501 ctgcaggtaa agacttgatc gaagttgaag aagttgaatt ggaaccatct cttggtaatg
    28561 gtggtttggg acgtttggct gcctgcttta tcgactcaat tgctactctt ggtttgaatg
    28621 gtgacggtgt tggtcttaac taccactttg gtcttttcca acaagttctt aaaaacaacc
    28681 aacaagaaac aattccaaat gcatggttga cagagcaaaa ctggttggtt cgctcaagcc
    28741 gtagctacca agtaccattt gcagacttta ctttgacatc aactctttac gatattgatg
    28801 ttactggtta tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg gattcagttg
    28861 attcttctat tattaaagat ggtatcaact ttgacaagac agatatcgct cgcaacttaa
    28921 ctctcttcct ttacccagat gatagtgacc gtcaaggtga attgctccgt atcttccaac
    28981 aatacttcat ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc gaaaaaggaa
    29041 gcaacttgca tgaccttgct gactacgcag ttgtccaaat caacgatact cacccatcaa
    29101 tggtgattcc tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt gacgaagcaa
    29161 tctcaattgt tcgtagcatg actgcctaca ctaaccacac aatccttgct gaggcgcttg
    29221 aaaaatggcc tcttgaattc ttgcaagaag tggttcctca cttggtacca atcatcgaag
    29281 aattggaccg tcgtgtgaag gcagagtaca aagatccagc tgttcaaatc atcgatgaga
    29341 gcggacgtgt tcacatggct cacatggata tccactacgg atacagtgtt aacggggttg
    29401 cagcacttca tactgaaatc ttgaaaaatt ctgagttgaa agccttctac gacctttacc
    29461 cagaaaagtt caacaacaaa acaaacggta tcactttccg tcgttggctt atgcatgcta
    29521 acccaagatt gtctcactac ttggatgaga ttcttggaga tggttggcac catgaagcag
    29581 atgagcttga aaaacttttg tcttatgaag acaaagcagc tgtcaaagaa aaattggaaa
    29641 gcatcaaggc tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac caaggtgtgg
    29701 aaatcaatcc aaattctatc tttgatatcc aaatcaaacg tcttcacgag tacaaacgcc
    29761 aacaaatgaa cgctttgtac gtgatccaca aataccttga catcaaagct ggtaacatcc
    29821 ctgctcgtcc aatcacaatc ttctttggtg gtaaagcagc tccagcctac acaatcgctc
    29881 aagacattat ccatttaatc ctttgcatgt cagaagttat tgctaacgat ccagcagtag
    29941 ctccacactt gcaagtagtt atggttgaaa actacaacgt tactgcagca agtttcctta
    30001 tcccagcatg tgatatctca gaacaaatct cacttgcttc taaagaagct tcaggtactg
    30061 gtaacatgaa attcatgttg aacggagctt tgacacttgg tactatggac ggtgctaacg
    30121 tggaaatcgc tgagttggtt ggagaagaaa acatctacat cttcggtgaa gattcagaaa
    30181 ctgttatcga cctttacgca aaagcagctt acaaatcaag cgaattctac gctcgtgaag
    30241 ctatcaaacc attggttgac ttcatcgtta gtgatgcagt tcttgcagct ggaaacaaag
    30301 agcgcttgga acgtctttac aatgaattga tcaacaaaga ctggttcatg actcttcttg
    30361 acttggaaga ctacatcaaa gtcaaagagc aaatgcttgc tgactacgaa gaccgtgacg
    30421 catggttgga taaagtcatc gttaacattt ctaaagcagg attcttctca tctgaccgta
    30481 caatcgctca gtataacgaa gacatctggc acttgaacta atactcttcg aaaatctctt
    30541 caaaccacgt cagctttatc tgcaacctca aagcggtgct ttgagcaacc tgcggctagc
    30601 ttcctagttt actctttggt tttcattgag tataagatac aaatttatac taatacattt
    30661 tgtaaaaaag cgagtttcga ttgaaattcg cttttttaaa tgctgtagat ttgggtcaat
    30721 cttgtctaaa aatagggaaa tcctagatac agtgaagact ttaaatgctg gtttttactg
    30781 tcctcagcct tatatttttt cgtagttgat tacctcacac ctcttgtatt cgcttacata
    30841 aagtattata atataattgt aggaaagaag gtgtttttat gatatacaca cttaaattgg
    30901 tgttgtttat tacctttctt gtaataagct tgttacctga taagattttt ggaaaaaata
    30961 aaaaaatttg gaaaatagtt tttgcaatat tgacggcagt ggcagcattg tcatttatgt
    31021 actaagttat tttaagaatg tagggaaata aaccctacat tctttttagt tttttctgtt
    31081 ttctaaattc tatttatcca agcgcttcaa catttcttgc ttcttcgctt caagttctgc
    31141 acgcttttct tcgatttcgg catgtttttt ctcgagttca gaacaacttg caccattgct
    31201 aaattctttt cgccatcagg agatagggtg agtcgacatg tctattactc acccaaagca
    31261 gtcctacaaa gcaggaattt tctgttactt ttttggaaat agtaacgttt atacagcttt
    31321 gacacttcgt atcaaagcgc caaacacact ccgagggatt tacagaaagc agaaaaggaa
    31381 tgatctggta taagatcatt ccttttctct ctttttcttt aagtaattat atacaatgta
    31441 cgacgaagtc gtcattgcaa tgctgatcca ccacctaaag ggaactttaa acaacattga
    31501 taagataaag aatataaaca acgaaaatac gttataccca attaatttta ttgtatatct
    31561 catgattaaa agttaatcct tccgttgtta ggaatggcat catttttatc ccataattgt
    31621 gctaaataag tccccggtga taataaattc atagcggatt ctaaagcaac atcatttaca
    31681 aaccaactac ctagatatct agaaattgct gaacgaatag cactttttgc tgcatgtttt
    31741 ccttttactt taattagatt tgcaaggcct gcagtagttc ctcctaatgc taaagctatt
    31801 gtagtatcta atagagcacc catttgatta actgtaatac cttgccaagc tgctctaaat
    31861 ggagagtatg taggtgggat tgtataatcg ccttgtaatt gtcggttaat tacttctttg
    31921 atccattgtt gtgagacgtc tggatgaaaa gattggattt cgtttgcaag tgtattgatt
    31981 tgttcttctg ttagagaagt gacaggttga agttccatat ttgtttcaat ttgcgatact
    32041 tgttcagaag cgtatacagc tgaaacactt ggaatcgctg atacaattaa cacaattgac
    32101 gtcaaaaaaa ccgaaataaa tttcattaat ttgttcatga gcttttctcc tttttatttg
    32161 tatctgctta cattttatta tatactgtta ttatagtcaa gaaaaatatg ctattatgtt
    32221 aaaaaaatat ttttcaaaat ataaatggac ggatttattt tggattttat ttgttatttt
    32281 gacctgcctc tatattggta accatgattt gtttactctc aatcatcaag aattctcttt
    32341 tcgtggtagc ttttggggtt tggtactggc cttatatcac ttattgttca ttgataagtt
    32401 tgtaatttcg aatcgaaaat aaagattaga actatgattg actggctact tttaatattg
    32461 attttggagg aagattttgt ctctattatt tattatttta aatttatcta ttttgtacaa
    32521 tatctattct ttgagacggg agaaatcgaa atacttgatt tatacggcct atatcatatt
    32581 tggggtaaat gtagtatatg gtattcaatg gttattaaga gaactgattt caactatttc
    32641 cccttaatgt gtatggaaac tataacaaaa cgcataagat taaggtttgt gtacctgttc
    32701 ttatgcgttt ttgtaatatt gaagattttc ggtaagtttt atacctttgg gaagtctagt
    32761 ttagaatgct ttcccaacca gaatctctgc ttcgatggta atctctgtca gttggctcca
    32821 gtcaatcttg ctctggtcaa catgaaagag gagaggagtc atactgagta gggcttggag
    32881 ttgttctgct gtgatagtct tagtcagaga ggcagtttga ctagatagga tggtaaagtg
    32941 ttcctggaaa tgctccttga tatcttggtt agaatactcc ttgtttgtca gctggtcctg
    33001 tactctttga cggatttctt tgaggtgatt ttcagttggg ataaccttta tcaagatacc
    33061 gtctttggat aaaacgcgac gaaattctcc atagttggca ggtgagaaga tatcaagcag
    33121 aatatccatg ttagcgtctt ttataggaag tcgtgccaag tcgccaacga accaattgac
    33181 tgcccagttg ggttcacttt tagcagcgat ttggactgaa tctttggaga tgtcaaaggc
    33241 atagaaagtt ttttcagagt gactttcttg tagtttgcga gaatagaatc cttcaccaca
    33301 accgatatcc aaaattgttg tggtagtttt tgagcttgca agcaagtcag atacagcatc
    33361 taagatagct tggtaaaagc cggcttctag gatttgttga cggttttgaa aattttcctt
    33421 gtcatagtta gcagattgct tgatttgagg tgctagattg acatagccaa atttcgccaa
    33481 gtcaaaagaa tgacggttgc agcacttgaa attagtctct aacagagtca gattttcttg
    33541 acagatagga caggcaaagg cagtcgcaga agcaaaacgc tgaagtttgg gcttgagatt
    33601 tgtattcata gtttaagtgt atcaaaagag gcaaatgaaa gcaactttag gaataagtag
    33661 atgggagatt cagtagaaat aaaactaatt ctccaattta tagaatgaaa ttgcttttat
    33721 atctaaattg ctatataata atgataagga ggaaataagt atgttaaaag aagtattaac
    33781 cgttgcaaaa gttgcgaaaa aatcttcatt atttttgggt ggtgtcgcat ttggtaccct
    33841 tggtttgaaa atcttagcaa gtaaggaagc taaaaaaggt tattctaaag ctttggctaa
    33901 ggcttacaag ttgaaagacg agctagatgc atctgtttct gttgtgaagc aacatggaga
    33961 cgatgtcttg caagatgcca aatatttgta cgagcaagag aaaaaagaag agcaattaga
    34021 tagccttata ggtgaataat atgtctttta aagtgctaca tagaggatac caacatatcc
    34081 gactatcatc ttctttttca cttaccttgg atattcaaga ctatcttcgt tccttggcga
    34141 gagatgaaaa ggggattgag tctatccagt tttacatgga tcaacagcac tttactctac
    34201 gcataaaaga aggcttttct gtattagata atgcagaagc ctttttaaaa agaattgata
    34261 aagggaaagt ttctgagttg atgactcttc ccattcgtag agaagagagt gcttattcta
    34321 ttgtttcagg tgcagcggtt aagcgtgtac tttttcgtag ttttgtgccg tatcctattc
    34381 gctatatatg gacttgttat caggctttgg gttatattag agaagcctat caaacactag
    34441 cgcgtaagga actaacgatg gaagtcttgg actgttcggc tattttattg tctttgttta
    34501 tgaaccaatc caagacagct agcaatatca tgtttatgct tgatttgggg aatcatttag
    34561 atcagtggtc cttgaaaaaa actgcaacag atttagaaca gagtcttctt gcaaaagaga
    34621 gcgatgtatt cctagtacag ggcgatacgg ttgttagtat caagagttcc gatgttcaaa
    34681 taggagatgt cttgatctta tctcaaggaa atgaaattct gtttgatgga caagtagttt
    34741 caggtttagg tatggtcaac gaaagttcct tgacaggaga gagttttcca gttgaaaaaa
    34801 gagagtctga tttggtttgt gcaaatacag tattagaaac tggagagtta cgcattcgtg
    34861 taacagataa tcagatgaac agccgtattt tacagctgat taagttgatg aagaaatctg
    34921 aagaaaacaa gaaaacgaaa caacgctatt tcatcaagat ggcggataaa gtcgttaaat
    34981 ataatttctt gggggctggg ctgacttacc tattgacagg ttctttttct aaggctattt
    35041 ctttcctatt ggtcgatttc tcctgcgctt tgaaaatctc tactcctgta gcttatttga
    35101 cagttatcaa ggaagggttg aaccgtgaaa tggtgattaa ggatggagat gttctggaga
    35161 aatatctgga agttgatact ttcttgtttg ataagacagg aacaatcaca actagttatc
    35221 ctatagttga aaaggtgtta ccttttggag actatagtga ggaagatatt ctcagaatca
    35281 gtgcctgtct tgaggaacac atttatcatc ctattgctaa tgccatcgtc aagcaagctg
    35341 agatagaggg aattgaacat gaggaaatgc atgggaaact ccaatatatc gcaagcaagg
    35401 ggatcaaatc tcatatagat ggccaaccag ttcttattgg gaattatgtc ttgatgcagg
    35461 atgagcagat tcatatcagt tcagaacaaa atgctttaat tgaagagtac aagagtcact
    35521 acaatctctt attcttggct tatcaaaatg aattgattgg aatgttctgc attcatactc
    35581 ctttgagaaa agaagcaaaa acagccttgg ataaacttaa ggcacagggg aaaaaattga
    35641 ttctggcaac aggagacacc ttgattagga cagaggaatt agtcaaagat ttgccctttg
    35701 atcaggtcta tacagacttg aaacctgatg ggaaatttga gttagtagag aaactgcaga
    35761 aagcaggtca cactattttg atggttggag atggattgaa tgactcagcg gctttaactc
    35821 tatcagatat cggtgtggtg atgaatgaga gtgcagatat ttctaagcag atgagtgata
    35881 tcttattgtt agataatcgt ttggatttct tccaagagtt ggattcgtta tcatcatctt
    35941 tgcaaacact catcaagaaa aatattcaag ataccgttgt cgtaaatagt agtttgattg
    36001 gctttggctt atttaattgg ctcagtcctt caaatctctc tatcttacat aatctaacaa
    36061 ccttgcgcat tgtcctgcgt agcctgtcta ttaaaaatag atagatgaga gttattaaca
    36121 gcaaaaagga gttacctttc tcgaggttaa ctcctttgtt tatagataaa tgttgaatgg
    36181 tttagtaagt caatacaaag tattttttct tcccacgacg gataacagtc agttcatttt
    36241 ctaacttatc agcgtcactc aagacatagt caaggtcttg gatgcggtcg ccgtttacgt
    36301 agatggctcc gttttggacg tcttcacggg cttggcgttt tgagttaact ataccagatg
    36361 agacgagcag ttccacgata ttgttgtttt cgtctgcctg tacttggtag tttggcacac
    36421 cacgaagtcc ttgtttgagc tctttgacag aaaggttttt gatgtttcct gcaaagagtt
    36481 gctcagtgat gttaagtgct tctttgtagg cttcttctcc gtgaacaagt gtaacaactt
    36541 cacgagccaa gactttttga gccaagcgtt cgtgtggcgc tgcttcaaat tgtttacgaa
    36601 tatcttcaat ctcatcaagt gacaagaaag taaagatttt caagaagcga acagcgtcag
    36661 cgtccatcac gttcatccag aattggtaca tttcgtatgg agaagtcttt tcgggattga
    36721 gccagacggc atttccttct gatttaccaa attttttacc agttgcatct gtgattagtg
    36781 gaacagtgat aacgtgacca gtcttgtccg ccttacgacg aagcaattcg gtaccagctg
    36841 tcatatttcc ccactggtca gaaccaccga tttgaagagt gacattatgg tcttggttaa
    36901 ggacgaagaa gtcgtaccct tgcatgattt ggtaagcgaa ctcagtgtaa gaaattcctg
    36961 tttcgatccg ttttttaaca gattccttac tcatcatgta gttgaccgtg aagtattttc
    37021 caatgtcacg gaggaagtca atgaagctga tgctgccaaa ccagtcgtag ttgttgacca
    37081 tgacagcctt gttttcgcca ttttcaaagt caagaaaacg agaaagttgt ccttggatag
    37141 acttgaccca gccatctact gtgtcttttg tttggagact acgttcagca tctttgaagg
    37201 acggatctcc gatgagacct gtagcaccgc caacgagcgc ataaggtttg tgacctgcta
    37261 gttgcaagcg acgacttgtc aagattgcga caaggtggcc taggtgaagg ctgtcagcag
    37321 ttggatcgta gccagtataa taagaaactt gaccttcttc tagggcttta cgcaaagctt
    37381 cttcatcagt cgtttgaaat atcaaaccac gctcttttag ctcatcaaaa atgtgcatgt
    37441 gtcttttctc ctttttaaaa ttattgtttc tacctattgt atcacaaact tgggcaatag
    37501 cctagcagaa tagggaagaa agtggctatt ttattgaaaa tttccctttt gtggtataat
    37561 agatagagtg aggaaatcca tgcaaaatca attaaatgaa ttaaaacgaa aaatgctgga
    37621 atttttccag caaaaacaaa aaaataaaaa atcagctaga cctggcaaga aaggttcaag
    37681 taccaaaaaa tctaaaacct tagataagtc agccattttc ccagctattt tactgagtat
    37741 aaaagcctta tttaacttac tctttgtact cggttttcta ggaggaatgt tgggagttgg
    37801 gattgctttg gggtacggag tggccttatt tgacaaggtt cgggtgcctc agacagaaga
    37861 attggtgaat caggtcaagg acatctcttc tatttcagag attacctatt cggacgggac
    37921 ggtgattgct tccatagaga gtgatttgtt gcgcacttct atctcatctg agcaaatttc
    37981 ggaaaatctg aagaaggcta tcattgcgac agaagatgaa cactttaaag aacataaggg
    38041 tgtagtaccc aaggcggtga ttcgtgcgac cttggggaaa tttgtaggtt tgggttcctc
    38101 tagtgggggt tcaaccttga cccagcaact aattaaacag caggttgttg gggatgcgcc
    38161 gaccttggct cgtaaggcgg cagagattgt ggatgctctt gccttggaac gcgccatgaa
    38221 taaagatgag attttaacga cctatctcaa tgtggctccc tttggccgaa ataataaggg
    38281 acagaatatt gcaggggctc ggcaagcagc tgagggaatt ttcggtgtag atgccagtca
    38341 gttgactgtt cctcaagcag catttttagc aggactccca cagagtccca ttacttactc
    38401 tccttatgaa aatactgggg agttgaagag tgatgaagac ctagaaattg gcttaagacg
    38461 ggctaaggca gttctttaca gtatgtatcg tacaggtgca ttaagcaaag acgagtattc
    38521 tcagtacaag gattatgacc ttaaacagga ctttttacca tcgggcacgg ttacaggaat
    38581 ttcacgagac tatttatact ttacaacttt ggcagaagct caagaacgta tgtatgacta
    38641 tctagctcag agagacaatg tctccgctaa ggagttgaaa aatgaggcaa ctcagaagtt
    38701 ttatcgagat ttggcagcca aggaaattga aaatggtggt tataagatta ctactaccat
    38761 agatcagaaa attcattctg ccatgcaaag tgcggttgct gattatggct atcttttaga
    38821 cgatggaaca ggtcgtgtag aagtagggaa tgtcttgatg gacaaccaaa caggtgctat
    38881 tctaggcttt gtaggtggtc gtaattatca agaaaatcaa aataatcatg cctttgatac
    38941 caaacgttcg ccagcttcta ctaccaagcc cttgctggcc tacggtattg ctattgacca
    39001 gggcttgatg ggaagtgaaa cgattctatc taactatcca acaaactttg ctaatggcaa
    39061 tccgattatg tatgctaata gcaagggaac aggaatgatg accttgggag aagctctgaa
    39121 ctattcatgg aatatccctg cttactggac ctatcgtatg ctccgtgaaa agggtgttga
    39181 tgtcaagggt tatatggaaa agatgggtta cgagattcct gagtacggta ttgagagctt
    39241 gccaatgggt ggtggtattg aagtcacagt tgcccagcat accaatggct atcagacctt
    39301 agctaataat ggagtttatc atcagaagca tgtgatttca aagattgaag cagcagatgg
    39361 tagagtggtg tatgagtatc aggataaacc ggttcaagtc tattcaaaag ctactgcgac
    39421 gattatgcag ggattgctac gagaagttct atcctctcgt gtgacaacaa ccttcaagtc
    39481 taacctgact tctttaaatc ctactctggc taatgcagat tggattggga agactggtac
    39541 aaccaaccaa gacgaaaata tgtggctcat gctttcgaca cctagattaa ccctaggtgg
    39601 ctggattggg catgatgata atcattcatt gtcacgtaga gcaggttatt ctaataactc
    39661 taattacatg gctcatctgg taaatgcgat tcagcaagct tccccaagca tttgggggaa
    39721 cgagcgcttt gctttagatc ctagtgtagt gaaatcggaa gtcttgaaat caacaggtca
    39781 aaaaccaggg aaggtttctg ttgaaggaaa agaagtagag gtcacaggtt cgactgttac
    39841 cagctattgg gctaataagt caggagcgcc agcgacaagt tatcgctttg ctattggcgg
    39901 aagtgatgcg gattatcaga atgcttggtc tagtattgtg gggagtctac caactccatc
    39961 cagctccagc agttcaagta gtagttctag cgatagcagt aactcaagta ctacacgacc
    40021 ttcttcttca agggcgagac gataattctc taaatgaagt ggccaatcaa tggattgcca
    40081 cttttttcct ttcgtgttac aataagggta tgaatcagta tcagaaaaag attgttaacg
    40141 gaaaaattta ttcgctccta tccggcttaa tatggggaat ctgtggaatt ttaggagagt
    40201 acttctttac tcattatcag gtgtcttcgg gctggattac ctctatgcgt ttgacactgg
    40261 cagggagtct tgtactcatt tggtctgcaa tacaattaaa atcgcaagtg ctagatattt
    40321 ggcgagacaa gaaaaattac ctgccctttt tagcctatgc tattttgggg attttttcag
    40381 ttcagtattt tttctatctc tgtgtagaat actcaaatgc tacgacagca actattttac
    40441 agtttattag ccctgttttt atcctctttt acaatcgctt ggtttatcaa aaacgagcgt
    40501 caaaaagcgc tgttttctat gttttggttg ccatgctggg tgtttgcttg atggcgacaa
    40561 agggagatct ctctcagtta tccatgacgc cgctagctct tataacaggt ttgctgagtg
    40621 ccatgggtgt tatgtttaat gttatcttgc cccaaccttt tgctaagcgt tatggttttg
    40681 ttcctacggt tgggtggggg atgattttgg caggtttgtt tagcaatgtc ctctcgccgg
    40741 tttatcagct ttcctttact cttgatattt ggagtatctt gatttgcctc attatcgctt
    40801 tctttggaac ggcttttgct tttttcattt ccatgaaggc tgtgtccttg gtttctcctt
    40861 tggtggttgc cgttatcagt gccagtgaac ctctctcttc tgctctcttg agtgttttgt
    40921 tcttaggatt agtagtggat tggtccctcc ttctagctat agccttgatt attttaccca
    40981 tgatattttt gtctatagaa gaagcgaaag aaagtagata aaaagtcttt tcttaattct
    41041 aaaagtgtgc tatactagaa tagtcaataa aacacgggga gatagttgtg aagagtgttt
    41101 ttaggttgta tcggtagggg cttgctttta ccgacagcac gttttatctc acatccctaa
    41161 aaaatcatac ctaaaaacag acaaaaaggt ttcaaatttg aggccttttt tggtagaata
    41221 ggtatcatta taacgaacca ggaggcacct atgactgcta caaaaatgaa cgctcaagaa
    41281 attatccaat ttatcgccaa tgctgaaaag aaaaccagtg tcaaagtaac ctttgagggg
    41341 caactcgcaa ctgctgtgcc tagctctgtt gtcaaactag gaaatgtcct attcggagac
    41401 tggaaggacg tggctccgct tcttgaaggt ttggtagaaa atcaagatta tgttgtcgag
    41461 caagatgctc gtaattctgc agttcctttg ctagataagc gtgctatcaa cgctcgtatc
    41521 gagccaggtg ctattatccg tgaccaggtg gaaattggtg acaatgctgt tatcatgatg
    41581 ggagctgtta tcaatatcgg tgctgaaatc ggtgctggaa ccatgattga catgggtgcc
    41641 atccttggtg gccgtgctat cgttggaaaa aatagccacg ttggtgcagg tgcagttttg
    41701 gcaggtgtga ttgagccagc tagtgctgaa ccagtccgtg tcggagacaa tgttcttatc
    41761 ggtgctaatg cagtggttat cgaaggagtc caaatcggta gtggttcagt tgtcgctgca
    41821 ggagctatcg ttacccaaga tgtcccagaa aacgtggtag tagcaggtgt tccagctcgt
    41881 atcatcaaag aaattgatgc ccaaacccaa caaaaaacag cgctagagga tgcgcttcgt
    41941 accttgtaat tgtaaaagta aaaaagaggc ggaacccttt ttccagcctc tttctgctat
    42001 aacggaggac agatagatgt tagatttgat tcagactaga cgagctttac accagattcc
    42061 agagattggc ttggaggagt tcaagactca ggcttatttg ctggatgtga ttgagaaatt
    42121 gactacgggc aaggattttg ttcaaattcg tacttggcgg acagggattt tggtctacct
    42181 gcagggaagt cagccggagc gaaccattgg ttggcggaca gatattgatg gtctgcctat
    42241 cgtcgaacaa acaggtctac cttttgcttc tcaacaccaa ggtcgcatgc atgcctgtgg
    42301 ccatgatttt catatgacca ttgccttagg ctgtcttgag cgcgcccttg aggagcaacc
    42361 caagaataat ctgctctttc tatttcagcc tgctgaagaa aatgaagctg gtggcatgct
    42421 catgtatgag gacggtgctt ttggagattg gttgccaaac caattctatg gtctccatgt
    42481 tcgtccagat ttgaaagtcg gccagattgc gactaatact catacactct ttgcaggaac
    42541 ttgcgaggtg aagatccgtt tcaaaggcaa aggtggccac gcagcttttc ctcatgaagc
    42601 caatgacgcc ttggtggcgg ctagttactt tgtgacccaa gtgcagtcag ttgttagccg
    42661 caatgtcaac ccaatcgagg gagcagtggt gaccttcggc gtttttcaag ctggaaccac
    42721 caacaatgtc atcacagaca cagctttttt acatggaact attcgtgcct tgacacagga
    42781 catgagtctc ttggtgcaaa agagggtaaa aacagttgca gaaggggttg cagctgcctt
    42841 tgatatggaa gtcgaagtgg aactcaaaca aggtggatac ctacctgttg agaacaatcc
    42901 agccttggcg cgtgaactga tggacttctt tgacgaaaaa gacggaatcg agttgattga
    42961 tatcgaacct gctatgacag gcgaggactt tggttatctc ctttcaaagg ttgatggcgt
    43021 gatgttttgg ctaggtatcg atagtcccta cgctcttcat caccctcaaa tgagtcctaa
    43081 ggaagaagtc ttagctattg gggtggctgc ggtgtctagt ttcctgaaaa agaaggcagc
    43141 agaatagagg gcttgtctat gaaatcggaa ttacgcaagc aagtcttgca tgaaatgaag
    43201 gctatatctc aagagcaaaa acaggctata gaccaagctt taaccgagcg gcttttacac
    43261 catcccttct accaagaagc caaggtcatc gcaacctacc tctctttttc tcatgagttt
    43321 caaacgcggg aactgattga gcaggcgctg aaggacggca agaaggtttt aatacccaaa
    43381 acttatccca aggggcgcat ggagtttgtg gtctatgatc cgcaacagtt ggtaaaaact
    43441 tcctttgcct tactggagcc acagggagat gtggaagtgg tggatgcatc tcagattgat
    43501 ttgattcatg ttcctggtct ggcttttacg acgaaaggat atcggatagg atacggtgga
    43561 ggctattatg accgctatct ggaacatttt tctggtcgta ctttgagtac gatatatcct
    43621 tgtcaaattc aggactttat acctgaaaac catgatattc ctgttcagga ggtattaatt
    43681 gatgaaggaa atctttgata gacgttaccc tgtgacgagt ttcttcctct tagtgacggc
    43741 cttggtattt ttactaatgt tggtcactgc aggcggaaac tttgacaggg cagatacatt
    43801 atttcgattt ggagccatgt atgggccagc tattcgcctc tttcccgagc aggtttggcg
    43861 tctcttgtct gccatttttg ttcatattgg gtgggaacat ttcattgtta atatgctttc
    43921 actttattat cttggaaggc aggtagagga gattttcggt tctaagcagt ttttctttct
    43981 ctatctttta tcaggaatga tgggcaatct ctttgttttt gtatttagtc ctaaatcctt
    44041 agcagcaggc gcttctacct ctctttatgg gctatttgcc gcgattattg ttcttcgcta
    44101 tgcaactcgc aatccttata ttcaacagct agggcaatcc tatctgacac tttttgtggt
    44161 taacattatt ggaagtgttc tgattccagg aatcagccta gcaggccata tcggtggtgc
    44221 agttggtggc gcatttctag cagttatctt tccagttaga ggagaaaaac ggatgtataa
    44281 taccagccag agattaggag cggtagtctt gttcgtagga ctcgccattt tgcttttcta
    44341 caagggaatg ggaatgtgac gaagttgaaa gaaaatttgt gtaatgaaaa aagataaggc
    44401 attttttgaa ccttatcttt ttattttatt ttattccttc tcagtcaatt cttttccaag
    44461 ttggatgagg taattcttca aatcatcttt gacttgtggg tgtttgaggg cgtagtcgat
    44521 ggatgttttc atgaagccaa acttgtctcc gacatcgtaa cgagccccat tgaactcacg
    44581 agcaaataca cgttgtgttt tattgagggt gtcgattgca tctgtcagct gaatttcatt
    44641 tcctgcacct ggagcttggt tttcgaggat ttggaaaatt tcaggcgtga ggaggtagcg
    44701 tccgataata gcaaggtcgc taggagcgtc ctctggagct ggtttttcaa caaaggtttc
    44761 aacactgtaa agaccatctt ttccttcgcc ttgcggagca ataaccccgt aagcagatac
    44821 ttcgtcatga gggactggca tgacagcgat agtagacgcg tgggtacgct cgtagtcatc
    44881 catgagttgt ttggtaagtg gaacagcctt ttcgtctgtg atatccatca agtcatcacc
    44941 aagcataacg acaaaaggtt catttccgac gaaagcctta gcttgcaaaa cagcatctcc
    45001 gagaccgcgt ggatgagttt ggcggataaa atgcagacgc atgtcagttg ttttatcaac
    45061 tagcttcaaa agatctgttt tccctttttc tttgaggtta tattccaatt cgaagtttga
    45121 atcaaagtgg tcctcaatag aacgttttga tttaccagtg acaactagaa tatcttcaat
    45181 acctgatttg agagcttctt ccacgataaa ctggatagtt ggtttgtcta cgattggcaa
    45241 catttctttg gcaagggcct tggttgctgg taaaaatcga gttcctagtc cagcagcagg
    45301 gatgactgcc tttctaactt ttgatgtcat aaaaatcctt tctatagagg gttaagacca
    45361 ctcattttct gctttaaatt cattgttcat gatgtcataa atggcatctt tgatattggt
    45421 tccgtgataa ataacttggt aaatagcctg tgtaatgggc atatagactc caagttcttg
    45481 ggctagttca taggctgctc gagtcgttga aattccttcg attaccatgc ccatattagc
    45541 ttctatatca gctagggatt ctcctcgtcc gagagcatct ccagctctcc agttacgaga
    45601 gtggatggaa gttcccgtta cgatcaaatc tcccacacca gataagccgc tataggtcaa
    45661 tggactggcc ccgagtgcta cccctaggcg ggtgatttct gctaaacctc gagcgatgat
    45721 ggctgcctta gcattatcac caaatccaag accatgtaaa gctccagcac cgacagcaat
    45781 aatattttta agagcaccag cagtttcaac cccgataaca tccgtattgg tataaagtcg
    45841 gaagtagtga ttactaaata gcttctgaac gtattgagct gtttgtaaat ctttagaagc
    45901 agcagttatt aaagttaggt cacgcacaat ggtctcttct gcatgactag gccctgaaac
    45961 aacgacgata tcactacgga gatgttcagg aatttcttct tcaagaatgg ttgataatcg
    46021 tttatggcta tcaggttcta atccctttga tgcgtgcatg atgataacct tatggtccaa
    46081 ggtttgtgca acttgctggg caacaagtcg tgtcactttt gttgggacaa caaacaaaat
    46141 cgcatccaca tctttcaatg tttctgctaa gtcggtgtag gcaatgatat tttcgtctag
    46201 aacgacatct ttaaagtagt gcttattagt atggtgtgta ttaatttcat tgatttgctc
    46261 gggaagattt ccccaaatac gtacctcgtg tccattgtca tttaagactt gtgaaagggc
    46321 ggttccccaa gaaccaggcc ccaagacggc gacggtttgt ttttccatga tttcctcctt
    46381 gatagagttc tttctcttat tctatcatat tctaggggat tttgcacttg cattactggg
    46441 gtatggtgga aaaatacaca aaaaccgaga cgaagggata aactcttagt ctttagttaa
    46501 agtgagaaga aatctgatag atagtttgat tcagtatatg cttataatag aggtaaacaa
    46561 ctcaggaagt tcttgtaggt tgcgagagtt tggctaaaaa aatcagtcgt tcagaatttt
    46621 gtggtgatga gtctgaatta agtatccgtc aattaattag aattgaaaat ggagaatcca
    46681 gaccaacact aacaaagtta aaatatatcg ctgaacgttt gggggttgaa gattacaagt
    46741 tgatgccaag ttatatagag ttggataagg aatacctaga attgaagtat ttcttgatga
    46801 ggactcctac atacgaagat gaaactatcg cccaaaagaa agagagtgtt ttgataagat
    46861 ttttgaagag tattatgata ggctacctga ggaagaaaga tttatcatcc caaattattc
    46921 atatctggca ctaacgaact acacagttca aaaattacca gaaaagctag ttgaaatact
    46981 gtccttctgg tgattttgct taatttctga tgttcgagac ataattgagg agatttgtct
    47041 tgattttttc ctaaaaaagg gcagactcct cccttggttt gatgctcgat ttttaaaata
    47101 aggtgactta ttctgttagg catgttttcc cctgccctct agctctatat ggaacaggga
    47161 gtatcagatt tatctggcag attgtatcaa ataaggcttg aaactgtttt gaataggcat
    47221 atagacttga gaatttgaga atatgtcgtc tagcagtaga gacatatttt ccggcaatat
    47281 gaaggaagag acgtcgaaaa cgcttgatag tcaaggcctt tacttcatca ccagctagct
    47341 gctttaaaaa gaggtagaga ttataagcca gacagcccat catcatacgt acttcattct
    47401 taatcatggt cgaactatct gtcttatccc caaagaatcc tgctttcctt tctttgataa
    47461 agttttcagc attccctcgt tcacgataga attgaaacag ctcctcacta tctacactgc
    47521 ttaaattgtt caaatgaact tttttacaac cataaaaaag agcacttaat cgtactcttc
    47581 tcttttaagg attagttgaa ttaattcaaa tccaccagtt ctcctgtttc taggtagact
    47641 aggcgttcac aaatgttagc aatgtaatca gcgaagcgtt ccagatgccc tatgatataa
    47701 aggtattgag ttccattggg aattgaggtt tcttggtctt tcataagtcc aatgatttcc
    47761 tttgataagg cataataata ttggtcaatc tgttcatctt tttgagcaat actaatagct
    47821 tttgaggctt ggtgcaaagg aaaggcaacc aataaatcgg ctagcatgct gagggataat
    47881 ttacccattt ggtgtaactg ttcttcgtca ggggctagtt gattttcttt tagttgcaaa
    47941 acagctttag caatgcctgc catatggtct cccatacgtt caaggtctga acaagaagac
    48001 atgatgctaa tcacaaatcg aaggtcagac acttgtggct gctgcaaggc caacaaacgg
    48061 gcacaggtca attcgatagc gctttgacct tggttgatag catgatcctt attgataatt
    48121 agctctgcca tctccttgtc tttggaggct aaggccagta aggcttttga agctgtttca
    48181 aggacaagtt gccctagtcc taaaaaggat tgttctaatt catgcaattc taagtcaaat
    48241 tgatttctca taggtttttc cttccttatc cgaaccgtcc tgaaatatag tcttctgtgc
    48301 gctgatcttt tggattggta aacacgtcaa cggtatctcc aaattcgcaa atttctcctg
    48361 ttaagaaaaa agcagtttta tctgaaatac gtgaagcttg ttgcatgtta tgggtaacaa
    48421 tgataatcgt ataatccttt tttagttgct gaatgaggtc ttcaattttt aaagtggaga
    48481 tagggtctaa ggctgaagtc ggctcatcca ttaacagaat atcaggttct actgctaaag
    48541 ctcgcgcaat gcaaaggcgt tgctgctgac cgccagataa ggacatggca ctctttttaa
    48601 gatcatcttt gacttcttcc caaatggctg ccccttttaa agatttctcc actaaggcat
    48661 ctaattgttt tttgtctcga ataccatgtg tccttgggcc ataagccacg ttatcataga
    48721 tagacatggc aaagggatta ggctgttgaa aaaccatccc tacacgctta cgtagctgat
    48781 taaggttgaa tttgctacta taaatatctt gctcatctaa gaggacttgg ccttcaatat
    48841 ggcaagaagg aaccaaatcg ttcatccggt taagggtttt tagaaaagtt gatttgccac
    48901 aaccagatgg gcctatcaag gcagtaatct gtctttctgg taattgaatc gaaatatttt
    48961 ttaaggcttg aaaatccccg taaaataagt ctaggtgtct gactgaaaat gttcccatac
    49021 taggaagctc ctttcacaag ttttcgagat aataagcttg atagagtatt tatcattaaa
    49081 acagtaataa tcaaaatcac accggtagca taggcttcat tgacatgtag cccctcactt
    49141 gacagcatat acatatgcag ggctagagaa cgacctgaag acatgagact acttggcgta
    49201 ttggtagagg tacctaatgt atacatgagg gcagctgttt caccaacgat acggccaata
    49261 gctagtatca ctccagctaa aatacctggc atggcaactg gtagaacaat tctaaaaaca
    49321 gtccgtaact tacctgcccc aagtccataa cttgcttgac gcatgctatc actaacagat
    49381 aaaagggctt cttctgttga gcgaataatg actggcaaca ccatgataac tgaggttaag
    49441 attcctgata acagagagta ttgaaaacct aagaagacta caaagaagag catgccaaac
    49501 agaccaaaaa caatggaagg aatcccagac aaggtatctg aggccaatcg catgatttta
    49561 acacaaaggg aatctttttt tgtatattcc acaagataaa aaccagcaaa aatccctatg
    49621 ggcaaggcta aaagaagagc accaaagacc agaataacgg tggaaataat cgctggcata
    49681 agggaaatgt tctcagaagt ataagtccaa gaaaagaggg atagacttag atgaggtaag
    49741 cctttgatga ggataaaacc aatgattaaa aagagagagc caaaggttaa agctgaaaaa
    49801 caataaacga gaagttttag caggtattta ctcataagat gattttcctt tcaagtaggc
    49861 aaagtaggca ttaatcaaga gaataaggaa aaagagaact gctgaggttg caataagggc
    49921 ttccctatgc tgacctgatg cgtaagccat ctccagaaca atattggttg ttaaggttct
    49981 ggttcctgaa aagagtccac ttggaataat tggctggttg cctgccacca aaataactgc
    50041 catggtttca cctactgcgc gaccgattcc taaaataact gctgataaaa taccagatct
    50101 cgcagctggc aagatgacac taaaaatact ccgttcatga ctagctccta gagccaagct
    50161 accagaataa tacgttttgg gaactgttcg gatagcagat tctgacaaac tgataatggt
    50221 tggcaaaatc attattccta atagtaacga agcggttagg acactcatgc catttcctaa
    50281 aaagcttcta atccaaggca ccaataattg taggccgaaa aaaccataaa caatagatgg
    50341 aatggctgcc atcaagttga tagctgattt taagaagcca tagacgggct ttggacaata
    50401 ataaaccata aacaccgatg tcaagatgcc tgttggcacc ccaatcacaa tcgctcctaa
    50461 ggtaattaat aaggaaccaa cgatcattgg taaaatacca tagcttgccg gaatgttcgt
    50521 tggcgaccaa tcactgccta ataaaaaacg ggcaaagccg tagttagcta tgaaaggtaa
    50581 gccattacta aaaataaaga aacagattag caaaatagct acaacagcta ctgttgcact
    50641 catgaaaaaa attgccctaa aaactgcttc tttgaaggct tgttttgtca catcttgtcc
    50701 tttctagtga agaaagtaag ggagatacga cacctcccta cttgccttct ttatcttatt
    50761 gtacgatgaa acgtctgcat ctctttagag atttatggag caaacatttt atttaatctt
    50821 gtcccaggtg gttaatttgc cactaaaaac gtctgcaagt tcagccatac tgacttggct
    50881 tgccttattg tcattattga ccacaacagc aataccgtct aaagcaatag catcatgggt
    50941 gagactctta ccttcttcag gagttaattc cctagaaacc ataccaatat cagcggtttt
    51001 ctccttaaca gcggtaatac ctgctgaaga cccattagag gtaatatcaa tcgtaacttc
    51061 tggattttct tttttataag cttctgctaa tttttccatt aaagaagata ctgaagtgga
    51121 acctacaaca gacaacttgc ctgataagtg ttggcttgta tattctgtgg tttcggtttt
    51181 agcttcaata aatttattat ctgtgaccac ttgttgacct tgtttggagt ggataaagct
    51241 gataaaatct tgacctagct tggaaagatt agaagaccaa acaatgttga agggacgttg
    51301 aagagggtat ttaccatcta aaactgtgtc tcgactagcc ttgacaccat caatctctaa
    51361 agctttgaca gatttcgtta aagatcccaa ggagatgtag ccgatagcat tagcattccc
    51421 ttgaactgct gagagaacac cttctgtact attttgaatc acagctgttt tggcagtgtt
    51481 gtcaattttt ttatcaccgt cttttttgag aatccctgtg atttctgtga aggcaccccg
    51541 tgttccagag ccattttctc gtgaaatcac ctcaatcgtt cctgaagctg actgtttgga
    51601 agcagctgac tgattgccac aggcaacaag cccaaatcct gataagccaa tggctgcaag
    51661 agtaagcatt tttttgaatt tcataataat cacctttatc tctatgtatt tttcttgtgt
    51721 aggcttacta catttatagt ctaacaagtc tttgtaaagg tttatccctg attcatgtaa
    51781 agattgtgta aagaatcaaa aaaagccact tttgaaaaat ggctgctcct aaaaatagct
    51841 ttaaaaatta ttagtcctgt gcgaaagatt ggttaggaag aaaaatcgtg aagcaactgc
    51901 ctctgccaag ctgactcgtc accgtgactt ggccacctaa taattgactg agttctttga
    51961 caatggcaag gccaagacca gtgccaccag tttgtctgct tcgaccttta ttaactcggt
    52021 aaaaacgttc aaaaatacga tcctgctcta attgactaat accaatccct gtatctgata
    52081 cagaaatctt aatgccttcg ttcacctttt gggtcttgac ctcaattttt cccccttgtt
    52141 cagtgtaacg gatggcattg gataaaagat tgagtaagat ttgggaaagt aattgactat
    52201 ctgatacgag ggtgacatca tctggcacct gcacctttag ctgtaaatcc ttcttcttga
    52261 gctgaggttg caagctttga gtcaaatcct gtacaaattc tgccaaagaa agggtcgtcc
    52321 attgtatagg catttgttga gccttagata aggtaagaag atgctcaaca atatgctcaa
    52381 gacgcaagct ttctttgtaa ataatgtcta gaaagtcatc cttgagcgct tcttcttcag
    52441 ctgacatccc cttaatggtt tcagcaaagc ccttaatcga agtaactggt gtcctcaatt
    52501 catgggaggc atttgagaca aaggctaaat ttaacttttc ataagttcta atcgttgtta
    52561 aatcatatag caagacgagc acagcttcca cagattgggt ggggctaaaa acgggaactg
    52621 ctgtcacttc taaaatcaag tcaccctcat gaaacccact tacttcttgt tttaaccttg
    52681 ttttttgatc aaaggcttgg tgaactaaat ttcgaatatc catccgtttg aggtcatcaa
    52741 gtgaacttat gtcgccgtcc acatcgggaa aataatgagg cagagagcga ctggataata
    52801 acatctgacc ttgagcggaa actaaaaacg tccccatggt taggtgcgac agaagaacct
    52861 ccattgtttc ggctaggtcc ttgtattgct gatcctgttg ggagactttg gtttttaggg
    52921 cagacacata ctgagccaaa gactttaagt cttcttgccc tttttctaaa aagtattcac
    52981 tactggtcaa gagaggttgg tgcaaggtct caaaagcaac ttcccatttc caaaggcaaa
    53041 agagccagta gccaccttgt cccaaagaaa gggctagaag aaagagaccg atgcctttac
    53101 tgatccaagt taataccatc cctgcaatca gaatgaggct aacacttaga ttgactagcc
    53161 aaaattgaag gtagcgtttc atctataact ccttgaactt ataaccataa ccccgaatgg
    53221 ttcgaataaa ttgaggggct ttaggattgt cttcaatttt ttccctcaac ttaccaatat
    53281 gaacgtccac caaacgtgtt tcctgcccaa agtcataccc ccagatacgt tccaaaagac
    53341 gctctctagt cagtgtcatg ttgggatgtt tcataagata gagcaagagt tcaaattctt
    53401 ttggggtcaa actcagtaac ttattcgcct tgtagacttc atgacgctca gggtatactt
    53461 tcaaggtccc aaatagccaa gaatcgtcag cgatattatc tgaatcatct ccttcttgtt
    53521 ctcctttagt tcgcctgagg acagccttga cacgcgccag caattctcta gggctaaaag
    53581 gtttggtcag gtagtcatca gcccctaatt ccaaggccaa aaccttatca aattcatcac
    53641 ttttcgcaga aaccatcata attggagttt tgacgccttt ggctctcagc cgcttacaaa
    53701 cttccatgcc atctaattgt ggtaacatga tatcaagcaa gataaaatca aagggttctg
    53761 tttctgccaa agctaaggcc ttccgtccat ttgttaccaa ttgagtagaa aagccttcct
    53821 tacttaaatg gtagtcaagc aatttcagaa tgtgttcttc atcatccact aataagactt
    53881 gttttgtcat ctattatctc ctattggtaa cattataaca caattatcag aaatcctaac
    53941 attgctaaat cagattaaat ttgcttatca agactagtat ctggtcaaac gctcaatcat
    54001 ctccttgtgc tctggatagg tcgccagtag atctaccctt tcaaataatt caaaatcctc
    54061 aaattcaaaa ccaggagcaa caagacaaga aaccagagca tcatccttat caactgttga
    54121 tccccaaata gtgcccttag gaacacagta gtgaagttgt tgccctttgg atatgtccag
    54181 gcctaaagtg actgcttcgt agtgaccatc tgctgtaatc atgtgaacag taagtgggga
    54241 ttctgcatga aaataccaga tttcatctgc tgtcaatcgg tgaaaatgtg aaggattcgt
    54301 ttcttcttaa taagaaataa atactggtat aaagcgccct tcccttacca gcaaggttta
    54361 tagtgtctga agcttttttt gtttgtctaa aatagccacc ttcaacatgg ggagctaact
    54421 ctagagttct tatcaagtct tctttatccg tcggagccaa tgggttgaag taactcttgt
    54481 tcaaagtggt gttacgattt caagaactcc tctcagttct gaggacacgg taatgattga
    54541 tgcgacggaa gtacaaatca atcgccctaa aaaaagaatt agcgaatcat tctggtaaaa
    54601 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
    54661 tggatatcgc tgtgaactat agtcatgata tgaagttgtt caaaatgagt cgcagaaata
    54721 tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc
    54781 ctcaagcaca aattccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag
    54841 cctgtaacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
    54901 aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
    54961 tgaatttgat tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
    55021 ttatttggtt aggtgaatta gtgaagcgtt taggcaagtg tctctggtta cgacgtcatg
    55081 gcctctaaat cgattatatt taggggtcat gactagtgaa gcagttagct agttcgcata
    55141 taagcggcta gcgtctaaca attaggaact ttagttccaa taactttaag attacgacgt
    55201 tttaggacat aaatcgatca tatttatgtc ctaaaactag tgaagcgcct agccaaagtc
    55261 cgaataggat ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt
    55321 acatcttctc tggtgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg
    55381 ttgcgtagct gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat
    55441 gtgcatagta tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag
    55501 gttcaaagtt atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga
    55561 tttcccagct ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg
    55621 ctttgcgtaa gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac
    55681 cctcgaagga taccatagct tctaggtcga agtcgtatcc atttgtacgg tcagttttga
    55741 ggtcatagaa tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta
    55801 gttcaggatt tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag
    55861 gctctagcaa gatgacattc cctttacgag tagagagctt cttcccttct tttgtaacca
    55921 gaccaaaagg aacgtgggta atgtcgtcac tccaatcgta gcccatctct tgcaagacag
    55981 ctttgagttg tttaaagtgg gcagattgct cttgaccaac gacgtagata gatttagcaa
    56041 attggtattc atttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg
    56101 caccatcaga cttcttgatg agggctggat gttcaattcc atatttctca agattcacaa
    56161 cttgggcacc ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat
    56221 ccatcttatc attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat
    56281 tgtaaaggcg gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag
    56341 cttcctcatc tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag
    56401 ggtcattttc agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat
    56461 gagcttttac agcttcttcg tcgccccatt ttttataggc aacaatcaac atcccaaatt
    56521 gtttacccca gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa
    56581 tatgtgacaa gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag
    56641 cgatattcgg actagacatg tcgataacaa cattttcttg tttaccaata ttttggtcag
    56701 catagtgttc tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat
    56761 caaggaaaaa gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca
    56821 ttttttcagc cagttcagcc gcaatcattt gtggtgcttt acgttcgact tttgcaagag
    56881 aaaaagcagg gaaagcaatg tctcccattt ctgagttttt aggggtttcc agtaacttta
    56941 aaacagcctc ttggtccagg ctatcaatga tgctagataa ttcgctagca atcaattctt
    57001 ttgtattcat taagagctcc tttttggact tttctactat tttatcacaa ttttaaagaa
    57061 agaagaaaaa atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt
    57121 ataaatatgc acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa
    57181 aatgattact gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca
    57241 caatgtttgt gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa
    57301 ggtcaagaaa aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt
    57361 ggtggaattt ttgtctcatc atttagaagg tgttgcaaga gcagagttta ccttggtgct
    57421 tcataccaaa ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa acaaggatga
    57481 atggatttta ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca
    57541 cgttgccaaa ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg
    57601 gagttgctct caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta
    57661 tcacccggca tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc
    57721 tttcggatgg gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt
    57781 ctggaaattt ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt
    57841 gttccctatc attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg
    57901 gctatcgcag agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt
    57961 gttcaggtca ttacgccagg gacagtggtc gatagcagta agccggacag tcagaataat
    58021 tttttggttt ccatagactg cgaaggcaat caatttggcc tagcttatat ggatttggtg
    58081 acgggtgact tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt
    58141 aacctcaagg ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc
    58201 ctcagccgcc agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat
    58261 ttattggatt tgcgattggc aacggtggag caaacggcat ctagtaagct gctccagtat
    58321 gttcatcgga ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt
    58381 aaggatttct tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct
    58441 cgctcaggta agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg
    58501 gggatgcgtc tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc
    58561 caacgtcaag aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca
    58621 gacagtctca agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa
    58681 accaatccaa aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt
    58741 gcgattttag aagggatgga gcaacctact ctagcctatc tcatcgcaca actggatgca
    58801 atccctgagt tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt
    58861 acagatgggg gaattatccg gactggattt gatgagactt tagacaagta tcgttgcgtt
    58921 ctcagagaag ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt
    58981 atcagcacgc tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat
    59041 tcgcaactag gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa
    59101 cgctttggaa ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag
    59161 tcagccaacc tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc
    59221 cagcgtttac aagctctagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg
    59281 gttgtggctg aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat
    59341 atccggaaag ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca
    59401 aatacgattc agatggcaga agataccagt attcaactgg ttacagggcc aaacatgagt
    59461 gggaagtcta cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc
    59521 tatgttcctg ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga
    59581 gcagcagatg acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat
    59641 aatgccattt cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga
    59701 actgcaactt atgacgggat ggctcttgct cagtccatca tcgaatatat ccatgagcac
    59761 atcggagcta agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt
    59821 ttacaacact tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc
    59881 cttcacaaga ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt
    59941 gctggcttgc cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat
    60001 caaggaacag agagtcctcc tcccatgaga caaactagtg ctgtcactga acagatttca
    60061 ctctttgata gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatgtgtat
    60121 aatatgacac ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac
    60181 caagactcac tagttaatct agctgtatca aggagacttc tttgacaatt ctccactttt
    60241 ttgctagaat aacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt
    60301 tgtctatttt ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg
    60361 ccttggcttc gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt
    60421 atctgcagga agtattagac gccctcctta ctgggaaata tgaagctatt tatagtatcg
    60481 gggcttggtt gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc
    60541 tcgcagccta tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa
    60601 ttcaaacctt ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa
    60661 tgacaaatga tatcaaccag attcagaacg ttgtcatgat gaccttccaa attcttttca
    60721 gacttcccct cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt
    60781 ggtgggtgat tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa
    60841 tgatggggcc tcgttttgcc aagtttcaaa cccttcttga gcgcatcaat gccattgcca
    60901 aggaaaattt acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg
    60961 ctaagtttac agaggtctca gacgagcttt ttggtcaaaa cctttacatt ggttatgcct
    61021 tttcagtagt ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt
    61081 ggctggtcgc gggaatggtt cagtcggatc cgtctgttgt tggttccatc gcttcttttg
    61141 ttaattacct aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg
    61201 tcagccgtgc catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta
    61261 tgaccttcaa ggatatccca gatgaagagt tggttggaag ccttagcttt gaaaatgtga
    61321 cctttaccta tccaatggac aaggaaccga tgctgaaaga tgtgagcttt actattgaac
    61381 ctggtcaaat ggttggtgta gttggagcga ctggtgcagg aaagtcaacc ttggctcaat
    61441 tgattccacg tctctttgat ccacagaacg gggccattaa aatcggtggc aaggatattc
    61501 gagaagtgag tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc
    61561 tttttagtgg aacgattgca gataacttga gacaggggaa gggaaatgct actctatttg
    61621 aaatggagcg cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa
    61681 cctttgaaag tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga
    61741 tgtcgattgc gcgtgggatt gtcagcaatc cacgtattct gatttttgat gattcgacct
    61801 cagccttgga tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg
    61861 ggacgacaac cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct
    61921 tggttctaaa tcaaggacga ttgattggtc aaggtacgca tgcagacttg gttgccaaca
    61981 atgccgttta ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc
    62041 aatagtttta tctaaactat ttcttatttc aatttgatga tttggcgatg attttagagc
    62101 acggcaaaag gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt taatttcaga
    62161 aattacatca ctttttgttc gtcaaatggc agctcttttt ttaggatata aaacagggtt
    62221 cggataagtt tttttgcaag gtggatgatg gctacattgt aatgttttcc ttgttctaat
    62281 ttagtcttaa gataggcctt aaaagcaggc gaaaagcgag ggcatgcttt ggcagcttgt
    62341 atgagtacct accgcagatg aggggaactc cgtttgacca ttcttcctgc taaatcaatc
    62401 tgatctgact gataaataga agaatccagt ccagcgaaag cttgtaattg agcaggatta
    62461 tcaaaggcat gaatatttcg aatctcagct aaaatgaccg cccctaaacg atccccaatc
    62521 ccagtaaccg tcgtgatgac cgagttgaac tcagccatca agtcattgac acatgtttcc
    62581 gccttgtcaa tgagcccctt gtaatgtttg atgttttcat tacacgagat aaaacgtcta
    62641 tgcgttatca aactcattac caattaaaac aaaaagctgt ggttagatcc tttcggaaat
    62701 tgtcaagcga ttggaggaaa tgaactaatc cacagcggct tattccaagt ataccacttg
    62761 ggctttggca gtagctaact gcgctaaata taatataagg aggagtaaaa tgaagacagt
    62821 tcaatttttt tggcattatt ttaaggtcta caagttctca tttgtagttg tcatcctgat
    62881 gattgttctg gcgacttttg cccaagccct ctttccagtc ttttctggac aagcggtgac
    62941 gcagctagcc aatttagttc aagctcatca aaatggcaat ccagaacttg tatggcaaag
    63001 cctatcagga atcatggtca atcttggcct gctggttttg gttctattta tctctagtgt
    63061 aatatacatg tgtctcatga cgcgcgtgat tgcagaatcg accaacgaga tgcgcaaagg
    63121 tctctttggt aagcttgctc agttgacggt ttctttcttt gaccgtcgac aagatggcga
    63181 tatcctgtct cattttacca gtgatttgga taatatcctc caagccttta acgaaagctt
    63241 gattcaggtc atgagcaata ttgttttata cattggtctg attcttgtca tgttttcgag
    63301 aaatgtgacg ctggctctca tcaccattgc cagcacccca ttggctttcc ttatgctgat
    63361 tttcatcgtg aaaatggcac gcaaatacac caacctccag cagaaagagg tagggaagct
    63421 caacgcctat atggatgaga gcatttcagg ccaaaaagcc gtgattgtgc aaggaattca
    63481 agaggatatg atggcaggat ttcttgaaca aaatgagcgc gtgcgcaagg caacctttaa
    63541 aggaagaatg ttctcaggaa ttcttttccc tatcatgaat gggatgagcc tgattaatac
    63601 agccatcgtc atctttgctg gttcggctgt acttttgaat gataagtcta ttgaaacaag
    63661 tacagcccta ggtttgattg ttatgtttgc acaattttca cagcagtact accagcctat
    63721 tatccaagtt gcagcgagtt ggggaagcct tcagttggcc tttactggag ctgaacgaat
    63781 tcaggaaatg tttgatgcag aggaggaaat ccgacctgaa aaggctccaa ccttcactaa
    63841 gttgcaagaa agtgttgaaa tcagtcatat cgatttttca tacttgcctg ataaacctat
    63901 tttgaaagat gtcagcattt ctgcccctaa aggccagatg acagcagttg ttgggccgac
    63961 aggttcagga aaaacgacta ttatgaacct catcaatcgc ttttatgatg ttgatgctgg
    64021 tggtatttat tttgatggta aagacattcg tggctatgac ttagatagtc ttagaagcaa
    64081 ggtgggaatt gtattgcaag attcggtctt gtttagcgga acgattcgag acaatatccg
    64141 atttggtgtg ccagatgcta gtcaggaaat ggttgaggta gcagcaaaag caacccacat
    64201 tcacgactat atcgaaagtt tgcctgataa gtacgatact cttattgatg atgaccagag
    64261 catcttttca acagggcaga agcaattgat ttcaatcgct cgaaccctga tgacagatcc
    64321 agaagttctc attctcgatg aagcaacttc aaacgtagat acggtgacag aaagcaagat
    64381 tcagcatgcc atggaggtgg ttgtagcagg tagaactagt ttcgtcattg cccaccgctt
    64441 gaaaaccatt ctcaatgcag atcagattat tgtccttaaa gatggagaag tcattgaacg
    64501 tggtaaccac catgaacttt tgaagctagg tggcttttat tcagaactct atcacaatca
    64561 atttgttttc gaataagaaa gaagttgtcc tatgtgggca gctttttctt gtccataaaa
    64621 aatgtttatc acagccttaa aaaaaacata ttagacgaaa gtcattttga gtgatatgat
    64681 aggactatcg ttagcattcg aaaggagagg catcatggct agaacggttg taggagttgc
    64741 tgcaaatcta tgtcccgtag acgcagaagg caaaatcatt cattcatctg tatcttgtag
    64801 attcgcagag atcattcgtc aagtcggtgg tctcccttta gtcattcctg ttggtgatga
    64861 gtcagttgta cgtgattatg tggaaatgat tgacaaactc attttgacag gaggccaaaa
    64921 tgttcatcct cagttttatg gagagaagaa gaccgtcgag agcgatgatt acaatctggt
    64981 ccgtgacgaa tttgaattgg cactcttgaa ggaagcgctt cgtcagaata aaccaattat
    65041 ggcaatctgt cgcggtgtcc aacttgtcaa tgttgccttt ggtggaaccc tcaatcaaga
    65101 aatcgaaggt cactggcaag gactaccttt cgggacatct cactctattg agacagtaga
    65161 aggaagcgtg gtggctaagc tatttgggaa agaaagtcag gtcaactcag tccatcgtca
    65221 aagcattaaa gatttggcac ctaatttccg tgtaactgct attgattcaa gagaccaaac
    65281 tattgaagcg attgagtcta tcgacgagca ccgcattatc ggtttacagt ggcatccaga
    65341 gtttctggtt aatgaagaag atggcaattt agaattattt gagtatttat tgaatgaact
    65401 gtaacgattg gaacatctgg tcgttctttc ttttattttt tcaaaatttt tagaatgtgg
    65461 cattttacgc aaacgtttga attctgataa aaattggaga aattcgacaa aaaaacttga
    65521 aaaaaacgaa ggtaagcgtt atgatagaaa agaagaaata ttggaggaag aacatgtcac
    65581 atattaaatt tgattattca aaagttttag acaaatttgt tgcaccacat gaagtggaat
    65641 acatgcaatc acaagtaaca gcagcagatg aattgatccg taaaggaact ggtgctggta
    65701 gcgacttctt gggatggttg gaccttcctg aaaaatacga ccgcgaagaa tttgaccgca
    65761 tcttgaaagc tgctgagcaa atcaagtcag acagcgatgt tttggttgtg atcggtattg
    65821 gtggatctta ccttggtgca aaagcagcaa tcgacttctt gaatcaccat tttgctaact
    65881 tgcaaacaaa agaagaacgc aaagctccac aaatccttta cgcaggaaac tcaatctcat
    65941 ctacttacct tgctgacttg gtagagtatg ttgcagacaa agacttctca gtaaacgtaa
    66001 tttctaaatc aggtacaaca actgaaccag cgattgcttt ccgtgtcttt aaagaactct
    66061 tggttaagaa atacggtcaa gaagaagcta acaaacgtat ctatgcaaca actgaccgcc
    66121 aaaagggtgc tgttaaggtt gaagcagacg ctaacggttg gggaacattt gttgttccag
    66181 atgatatcgg tggacgcttc tcagtattga cagccgttgg tttgcttcca atcgcagcat
    66241 caggagctga cataaaagct cttatggaag gtgcgaatgc agctcgcaaa gactacactt
    66301 cagacaaaat ctctgaaaac gaagcttacc aatacgcagt cgttcgtaac atcctttatc
    66361 gtaaaggcta tgcaactgag atcttggtaa actatgagcc atcacttcaa tacttctcag
    66421 aatggtggaa acaattggct ggtgaatcag aaggaaaaga ccaaaaaggt atctacccaa
    66481 cttcagccaa cttctcaact gacttgcact cacttggtca atttatccaa gaaggaactc
    66541 gtatcatgtt tgaaacagtt gtccgtgttg acaaacctcg taaaaacgtg cttattccta
    66601 ctttggaaga agaccttgac ggacttggtt accttcaagg aaaagacgtt gactttgtaa
    66661 acaaaaaagc aactgacggt gttcttcttg cccacacaga tggtgatgta ccaaacatgt
    66721 atgtgactct tccagagcaa gacgctttca ctcttggtta cactatctac ttcttcgaat
    66781 tggcaattgc cctttcaggt tacttgaatg ctatcaaccc atttgaccaa ccaggtgttg
    66841 aagcttataa acgtaacatg tttgcccttc ttggaaaacc aggatttgaa gaattgagca
    66901 aagaacttaa cgcacgtcta taatagaaga aaagagtggt ttgcccactc tttttactct
    66961 ctttatccat agaaattgga ctcagccaag acttgtgata taatatagaa agcaaaaagg
    67021 cagacgccta gataatagga gaaactatgt caaaagatat ccgcgtacgt tacgcaccaa
    67081 gtccaacagg actactacac atcggaaatg cccgtacagc attgtttaac tacttgtatg
    67141 cgcgccatca tggtggaaca tttctcatcc gtatcgaaga tactgaccgt aaacgccatg
    67201 tcgaggatgg tgaacgttca caacttgaaa accttcgctg gttaggcatg gattgggatg
    67261 aaagtccaga atcacatgag aattatcgcc agtctgagcg tttggacttg tatcaaaaat
    67321 acatcgacca actattagct gaaggaaaag cctacaaatc ttacgttaca gaagaagagt
    67381 tggcagctga acgtgaacgt caagaagtag ctggcgaaac accacgctac atcaatgaat
    67441 accttggtat gagtgaagaa gaaaaagcag cttacatcgc agaacgtgaa gcagcaggga
    67501 tcatcccaac tgttcgtttg gctgtcaatg agtcaggtat ctacaagtgg catgatatgg
    67561 tcaaaggcga tatcgaattt gaaggtggca atatcggtgg tgactgggtt atccaaaaga
    67621 aagacggtta cccaacttac aactttgccg ttgttatcga tgaccacgat atgcaaatct
    67681 ctcatgttat ccgtggagat gaccatattg ctaatacacc aaaacagctt atggtctatg
    67741 aagctcttgg ttgggaagct ccagagttcg gtcacatgac cttgattatc aactctgaga
    67801 ctggtaagaa gttatctaaa cgtgatacta atacacttca atttatcgaa gattaccgaa
    67861 agaaaggtta ccttccagaa gcagtcttta actttattgc tcttcttggt tggaacccag
    67921 gtggtgaaga tgagattttc tctcgtgaag aactcattaa actttttgat gaaaaccgcc
    67981 tcagcaagtc accagcagcc tttgatcaga aaaaactaga ctggatgagc aatgattata
    68041 tcaagaatgc agaccttgaa accatctttg aaatggcaaa accattctta gaggaagcag
    68101 gccgtttgac tgacaaggct gaaaaattag ttgagctcta taaaccacaa atgaaatcag
    68161 tagatgagat tatcccattg acagatcttt tcttctcaga tttcccagaa ttgacagaag
    68221 cagagcgcga agtcatgacg ggtgaaacag ttccaacagt tcttgaagca ttcaaagcaa
    68281 aacttgaagc gatgacagat gataaatttg tgacagaaaa tatcttccca caaattaaag
    68341 cagttcaaaa agaaacaggt attaaaggga aaaatctttt catgcctatt cgtatcgcag
    68401 tttcaggcga aatgcatggg ccagaattac cagatacaat tttcttgctt ggacgtgaaa
    68461 aatcaattca gcatatcgaa aacatgctaa aagaaatctc taaataaaga ggatacaata
    68521 atggacatct gggaaaagat gtacgaagaa gcacagaaac tatacaatcc acatgaagta
    68581 tcagactttg tttatgccaa tcatgttgta gctgcagtag aagcagaaga tggacaaata
    68641 tttacaggat tctgtatgga gggaacctgt ggtgttttcc atctctgcgc agaacgggcg
    68701 accctcttca atatgtacca attttcagga caaactaagg ttaagaaagt attagccttt
    68761 cgagacaaac caccttatgg tggaagttca gccatgcctt gcggtgcttg tagagaattc
    68821 cttttagagc ttaatgctga aaataaagat gcagaattca tgatggacta taatataaga
    68881 aaaacagtta aagtcgcaga actaatccct tattggtggg gagaagaacg tgcttctaag
    68941 tttaatgagc gatagaagag tcagtataat tctggctttt tttactataa gttgaaaaaa
    69001 t
//
LOCUS       DAVLBN010000003        66707 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLBN010000003 DAVLBN010000000
VERSION     DAVLBN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.003"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(119..1054)
                     /locus_tag="VXC24_000146"
     CDS             complement(119..1054)
                     /locus_tag="VXC24_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0492330.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1051..1911)
                     /locus_tag="VXC24_000147"
     CDS             complement(1051..1911)
                     /locus_tag="VXC24_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0492331.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2019..4181
                     /locus_tag="VXC24_000148"
     CDS             2019..4181
                     /locus_tag="VXC24_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0492332.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4273..5532
                     /locus_tag="VXC24_000149"
     CDS             4273..5532
                     /locus_tag="VXC24_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0492333.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5546..6412
                     /locus_tag="VXC24_000150"
     CDS             5546..6412
                     /locus_tag="VXC24_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0492334.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6426..7259
                     /locus_tag="VXC24_000151"
     CDS             6426..7259
                     /locus_tag="VXC24_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0492335.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7260..7340
                     /locus_tag="VXC24_000152"
                     /pseudo
     CDS             7260..7340
                     /locus_tag="VXC24_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7617..9059
                     /gene="gtfA"
                     /locus_tag="VXC24_000153"
     CDS             7617..9059
                     /gene="gtfA"
                     /locus_tag="VXC24_000153"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0492336.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9197..10390
                     /locus_tag="VXC24_000154"
     CDS             9197..10390
                     /locus_tag="VXC24_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0492337.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11077..13056
                     /locus_tag="VXC24_000155"
     CDS             11077..13056
                     /locus_tag="VXC24_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0492338.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13123..14619
                     /locus_tag="VXC24_000156"
     CDS             13123..14619
                     /locus_tag="VXC24_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492339.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14619..15545
                     /locus_tag="VXC24_000157"
     CDS             14619..15545
                     /locus_tag="VXC24_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492340.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15554..16621
                     /locus_tag="VXC24_000158"
     CDS             15554..16621
                     /locus_tag="VXC24_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492341.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16632..17558
                     /locus_tag="VXC24_000159"
     CDS             16632..17558
                     /locus_tag="VXC24_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492342.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17633..18959)
                     /locus_tag="VXC24_000160"
                     /pseudo
     CDS             complement(17633..18959)
                     /locus_tag="VXC24_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(19114..19824)
                     /gene="treR"
                     /locus_tag="VXC24_000161"
     CDS             complement(19114..19824)
                     /gene="treR"
                     /locus_tag="VXC24_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0492343.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            20009..21976
                     /gene="treP"
                     /locus_tag="VXC24_000162"
     CDS             20009..21976
                     /gene="treP"
                     /locus_tag="VXC24_000162"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0492344.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            22154..23779
                     /gene="treC"
                     /locus_tag="VXC24_000163"
     CDS             22154..23779
                     /gene="treC"
                     /locus_tag="VXC24_000163"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0492345.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            24035..24283
                     /locus_tag="VXC24_000164"
     CDS             24035..24283
                     /locus_tag="VXC24_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0492346.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            24490..25284
                     /gene="racE"
                     /locus_tag="VXC24_000165"
     CDS             24490..25284
                     /gene="racE"
                     /locus_tag="VXC24_000165"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0492347.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            25281..26252
                     /locus_tag="VXC24_000166"
     CDS             25281..26252
                     /locus_tag="VXC24_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0492348.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            26228..26749
                     /locus_tag="VXC24_000167"
     CDS             26228..26749
                     /locus_tag="VXC24_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0492349.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            26746..27207
                     /locus_tag="VXC24_000168"
     CDS             26746..27207
                     /locus_tag="VXC24_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0492350.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            27198..27938
                     /gene="xerD"
                     /locus_tag="VXC24_000169"
     CDS             27198..27938
                     /gene="xerD"
                     /locus_tag="VXC24_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0492351.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            27938..28666
                     /locus_tag="VXC24_000170"
     CDS             27938..28666
                     /locus_tag="VXC24_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0492352.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            28685..29254
                     /locus_tag="VXC24_000171"
     CDS             28685..29254
                     /locus_tag="VXC24_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0492353.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            29241..29963
                     /locus_tag="VXC24_000172"
     CDS             29241..29963
                     /locus_tag="VXC24_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0492354.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            29963..30205
                     /gene="yidD"
                     /locus_tag="VXC24_000173"
     CDS             29963..30205
                     /gene="yidD"
                     /locus_tag="VXC24_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0492355.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(30430..31395)
                     /locus_tag="VXC24_000174"
     CDS             complement(30430..31395)
                     /locus_tag="VXC24_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0492356.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(31491..32243)
                     /locus_tag="VXC24_000175"
     CDS             complement(31491..32243)
                     /locus_tag="VXC24_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0492357.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(32240..33196)
                     /locus_tag="VXC24_000176"
     CDS             complement(32240..33196)
                     /locus_tag="VXC24_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0492358.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(33186..34145)
                     /locus_tag="VXC24_000177"
     CDS             complement(33186..34145)
                     /locus_tag="VXC24_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492359.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(34442..34552)
                     /locus_tag="VXC24_000178"
     CDS             complement(34442..34552)
                     /locus_tag="VXC24_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0492360.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(34568..35269)
                     /gene="galE"
                     /locus_tag="VXC24_000179"
     CDS             complement(34568..35269)
                     /gene="galE"
                     /locus_tag="VXC24_000179"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0492361.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            35670..36734
                     /gene="pepA"
                     /locus_tag="VXC24_000180"
     CDS             35670..36734
                     /gene="pepA"
                     /locus_tag="VXC24_000180"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0492362.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            36756..37052
                     /locus_tag="VXC24_000181"
     CDS             36756..37052
                     /locus_tag="VXC24_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0492363.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            37734..38177
                     /locus_tag="VXC24_000182"
     CDS             37734..38177
                     /locus_tag="VXC24_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0492364.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            38181..38945
                     /locus_tag="VXC24_000183"
     CDS             38181..38945
                     /locus_tag="VXC24_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0492365.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            38959..39687
                     /locus_tag="VXC24_000184"
     CDS             38959..39687
                     /locus_tag="VXC24_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492366.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            39680..41200
                     /locus_tag="VXC24_000185"
     CDS             39680..41200
                     /locus_tag="VXC24_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0492367.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDSIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            41545..42351
                     /locus_tag="VXC24_000186"
     CDS             41545..42351
                     /locus_tag="VXC24_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0492368.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(42517..43053)
                     /locus_tag="VXC24_000187"
     CDS             complement(42517..43053)
                     /locus_tag="VXC24_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0492369.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FIGQEVVQFYLDLLIPKN"
     gene            43186..44076
                     /locus_tag="VXC24_000188"
     CDS             43186..44076
                     /locus_tag="VXC24_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0492370.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            44320..44673
                     /locus_tag="VXC24_000189"
     CDS             44320..44673
                     /locus_tag="VXC24_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0492371.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            44674..45711
                     /locus_tag="VXC24_000190"
     CDS             44674..45711
                     /locus_tag="VXC24_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0492372.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(45757..46764)
                     /gene="galR"
                     /locus_tag="VXC24_000191"
     CDS             complement(45757..46764)
                     /gene="galR"
                     /locus_tag="VXC24_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0492373.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            46929..48107
                     /locus_tag="VXC24_000192"
     CDS             46929..48107
                     /locus_tag="VXC24_000192"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0492374.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            48126..49607
                     /locus_tag="VXC24_000193"
     CDS             48126..49607
                     /locus_tag="VXC24_000193"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0492375.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            49677..50081
                     /locus_tag="VXC24_000194"
     CDS             49677..50081
                     /locus_tag="VXC24_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0492376.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            50262..51026
                     /locus_tag="VXC24_000195"
     CDS             50262..51026
                     /locus_tag="VXC24_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0492377.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            51023..51484
                     /locus_tag="VXC24_000196"
     CDS             51023..51484
                     /locus_tag="VXC24_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV0492378.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(51534..52796)
                     /locus_tag="VXC24_000197"
     CDS             complement(51534..52796)
                     /locus_tag="VXC24_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0492379.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(52796..53377)
                     /locus_tag="VXC24_000198"
     CDS             complement(52796..53377)
                     /locus_tag="VXC24_000198"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0492380.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(53777..53872)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(54255..54494)
                     /locus_tag="VXC24_000199"
     CDS             complement(54255..54494)
                     /locus_tag="VXC24_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0492381.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(54539..54637)
                     /locus_tag="VXC24_000200"
     CDS             complement(54539..54637)
                     /locus_tag="VXC24_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0492382.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            complement(54649..55476)
                     /gene="xth"
                     /locus_tag="VXC24_000201"
     CDS             complement(54649..55476)
                     /gene="xth"
                     /locus_tag="VXC24_000201"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0492383.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            55610..56066
                     /locus_tag="VXC24_000202"
                     /pseudo
     CDS             55610..56066
                     /locus_tag="VXC24_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            56063..56593
                     /locus_tag="VXC24_000203"
     CDS             56063..56593
                     /locus_tag="VXC24_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0492384.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            56721..58466
                     /locus_tag="VXC24_000204"
     CDS             56721..58466
                     /locus_tag="VXC24_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492385.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            58456..60207
                     /locus_tag="VXC24_000205"
     CDS             58456..60207
                     /locus_tag="VXC24_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492386.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            60380..61072
                     /locus_tag="VXC24_000206"
     CDS             60380..61072
                     /locus_tag="VXC24_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0492387.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            61115..62341
                     /locus_tag="VXC24_000207"
     CDS             61115..62341
                     /locus_tag="VXC24_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0492388.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            63471..65630
                     /gene="pfbA"
                     /locus_tag="VXC24_000208"
     CDS             63471..65630
                     /gene="pfbA"
                     /locus_tag="VXC24_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0492389.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            65614..65910
                     /locus_tag="VXC24_000209"
     CDS             65614..65910
                     /locus_tag="VXC24_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492390.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            66253..66465
                     /locus_tag="VXC24_000210"
     CDS             66253..66465
                     /locus_tag="VXC24_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492391.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            66523..>66707
                     /locus_tag="VXC24_000211"
     CDS             66523..>66707
                     /locus_tag="VXC24_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0492392.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERVELI
                     KEDLIINESVLNIDKKG"
BASE COUNT        19644 a        12233 c        14791 g        20039 t
ORIGIN      
        1 ataggggatt tacccactac aaatattata gagacaataa aacttcagat ccgtaaaact
       61 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      121 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      181 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      241 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
      301 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
      361 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
      421 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
      481 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
      541 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
      601 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
      661 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
      721 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
      781 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
      841 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
      901 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
      961 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1021 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1081 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1141 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1201 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1261 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     1321 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     1381 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     1441 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     1501 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     1561 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     1621 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     1681 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     1741 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtaggacgta
     1801 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     1861 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     1921 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     1981 tgataaaata gagtcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2041 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2101 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2161 aacgagacca tgccttttca ggaaatccaa cagctactaa tcgaaccttt agtttagata
     2221 ctcaacgtca aatttttgga caacatggct taggagattt taggaaacca accatacagg
     2281 ttcagcataa tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     2341 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     2401 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     2461 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     2521 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     2581 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     2641 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     2701 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     2761 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     2821 gcattaatcc agaaaacttt tcttggaagt tagcccctga ggaatacttt gaaacaccgg
     2881 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     2941 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3001 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3061 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3121 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3181 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3241 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     3301 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     3361 aggtagtaga atacttgaaa agtgtcttag atcaactcct atcttatcat gagattgatt
     3421 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     3481 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     3541 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     3601 ttggtatgat acgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     3661 gtttaccaat tcaatacggt tcatcctatt tctatccaac catttctatg ggggctcatg
     3721 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccatg
     3781 tagcaatgat gggaaatttg ggctatgagc ttgatttgac aaatttatca gatgaagaga
     3841 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     3901 gacagcagta tagactaatt aatcctgata ctgcatccaa tgaagcagct gtacaattta
     3961 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4021 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4081 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4141 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4201 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4261 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     4321 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     4381 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     4441 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     4501 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     4561 attgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     4621 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     4681 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     4741 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     4801 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     4861 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     4921 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     4981 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5041 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5101 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5161 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5221 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     5281 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     5341 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     5401 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     5461 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     5521 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     5581 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     5641 agccttttac agttttacca actggacagg attgacttac aactacaaat ttgtcggctt
     5701 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     5761 aatcattacg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     5821 cttgaactct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     5881 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     5941 gattgggaat gcccttcata ttgaatttct ccaaaccagt cttttaggga ctaggtgggg
     6001 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6061 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6121 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6181 tatagtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6241 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     6301 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     6361 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     6421 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     6481 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaactcacta
     6541 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     6601 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     6661 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     6721 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     6781 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     6841 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     6901 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     6961 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7021 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7081 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7141 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7201 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7261 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     7321 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggtaag gtgaagctga
     7381 cgtggtttga agagattttc gaatagtata agaagagctc atggaatcta tagtctttga
     7441 cacagaggaa gagttcagct tgttgataat tctatgtaga aaacaagaaa gtagtacttt
     7501 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     7561 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     7621 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     7681 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     7741 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     7801 cagcttttgg tgattgggag gatgttaagc gtttaggtga gagatattat cttatgtttg
     7861 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     7921 atgaagccag tgaatttaaa gatctctttt taaactggga taagttttgg ccagaaaacc
     7981 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8041 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8101 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8161 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8221 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     8281 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     8341 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     8401 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     8461 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     8521 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     8581 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     8641 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     8701 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     8761 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     8821 aggaaatagc aaaagaagtg caacgatctg ttgtgaaggc ccttctcaat ctattttctt
     8881 tccgtaaccg ttcagaagcc tttgatctag aagggactat tgagatagag acaccaacag
     8941 ttcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9001 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9061 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9121 attgctaaaa aagtggtaca atataggata gcttactatt atctgaatca gctgatttgg
     9181 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9241 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
     9301 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
     9361 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
     9421 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
     9481 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
     9541 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
     9601 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
     9661 agaagtgact ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
     9721 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
     9781 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
     9841 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
     9901 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
     9961 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10021 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10081 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10141 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10201 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10261 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    10321 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    10381 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    10441 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    10501 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    10561 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    10621 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    10681 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    10741 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    10801 atattgttat aatttaattt gaattccaaa atcacattgt tccgtccgta tttcatttta
    10861 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    10921 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    10981 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11041 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11101 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11161 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11221 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    11281 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    11341 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    11401 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    11461 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    11521 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    11581 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    11641 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    11701 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    11761 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    11821 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    11881 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    11941 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12001 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12061 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12121 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12181 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12241 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    12301 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    12361 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    12421 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    12481 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    12541 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    12601 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    12661 tatttaggat ttgataatcc aaatagccct tcagtagttc aagttggttt gaaagaatac
    12721 gataaattag ttgatgaagc tgccaaagag acaagcgact tgaatgtccg ttatgaaaaa
    12781 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    12841 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    12901 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    12961 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13021 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13081 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13141 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13201 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13261 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    13321 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    13381 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    13441 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    13501 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    13561 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    13621 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    13681 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    13741 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    13801 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    13861 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    13921 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    13981 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14041 cgtttcaaga acacttggat tgatagcctc tcaacaggga ctttgacctt cttgcttgct
    14101 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14161 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14221 cttggtttat tgggtgctcc tgttacagcc atttggattc gtcgttacat gattgacttg
    14281 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    14341 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    14401 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    14461 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    14521 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    14581 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    14641 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    14701 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    14761 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    14821 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    14881 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    14941 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15001 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15061 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15121 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15181 ttcgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15241 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    15301 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    15361 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    15421 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    15481 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    15541 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    15601 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    15661 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    15721 gaccttcaca ggtatgctcg aagaaaatgg tcgtattgcc caaggtagta ttgactaccg
    15781 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    15841 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    15901 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    15961 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16021 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16081 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16141 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16201 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16261 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    16321 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    16381 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    16441 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    16501 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    16561 gattgcaaat ctccatgata agattcgtga aaaaatggga tttgcccatc tggctgacta
    16621 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    16681 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    16741 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    16801 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    16861 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    16921 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    16981 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaaatatt atccgtgaag
    17041 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17101 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17161 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17221 aaaaagagct cggcctgacc tatctcttca tcgcccatga cttgtcggtt gttcgcttta
    17281 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    17341 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagcg gtaccaatcc
    17401 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    17461 atgagactga taagccgtct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    17521 aaaccgaatt ggcacgttat caaaaaggac taaactagta atggttttat aatttccatg
    17581 tcaattttta tggaaattag gctctttgtc aactgtagtg ggttgaagtc agctaagctc
    17641 gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa atccgttttt
    17701 tgaagttttc aaagtttcga aaaccaaaag cattgcgctt gataagtttg atgagattat
    17761 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcgttgata atcttttctt
    17821 tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc ttaagattgt
    17881 cctcgataag ttcgaaaaat ttctctggtt ccttattctg gaagtgaaaa agcaagagct
    17941 gatagagctg atagtggtgt ttcaagtctt ccgaataact caaaagcttg tttaaaatct
    18001 ctttattggt taagtgcata cgaaaagtag gacgataaaa ttgcttatca ctcagtttac
    18061 ggctatcctg ttgtatgagc ttccagtagt gcttgatagc cttgtgttca tgggattttc
    18121 gatgaaactg attcatgatt tggacacgca cacgactcat agcacggcta agatgttgta
    18181 caatgtgaaa gcgatcaaga acgattttag cattcgggag tgaaacagtc taggagactg
    18241 tttcagcctg agcctagaaa tttgaaagcg aagctgttta gccaagtcat agtaagggct
    18301 aaacatatcc atagtaatga ttttgacgcg acatcggacg gctctatcat atttaagaaa
    18361 gtgatctcgg atgacagctt gtgttctacc ttcaagaaca gtgatgatat cgagcttttc
    18421 aaaatcttgc gcaataaagc tcatctccat ctcccgattg aaacagtcac tccccggact
    18481 gtttcaacgt cccaagacat aatcttaggc agatttctaa aattacactc aaagtggaag
    18541 tcattgagct ttcgaatgac agttgaagtt gagatggaaa gctgatgggc aatatcagtc
    18601 atagaaatct tttcaattaa cttttgagca atcttttggt tgatgatacg agggatttgg
    18661 tgattcttct tgacgataga agtttcagca accataattt tagaacaatg atagcacttg
    18721 aaacgacgct ttctaaggag aattctagta ggcataccag ttgtttcaag ataaggaatt
    18781 ttagaaggtt tttgaaagta atatttcttc atttgacttc cgcactcagg acaagatgga
    18841 gcttcatagt ccagtttggc gatgatttcc ttgtgtgtat ccttcttgat gatgtctaaa
    18901 atctggatat tagggtcttt aatgtctagt aattttgtga taaaatgtaa ttgttccata
    18961 tgattctttc taatgagttg ttttgtcgct tttcattata ggtcatatgg gacttttttt
    19021 ctacacaaaa taggctccat aatatccata ggggggttac ccactacaaa tattatagag
    19081 ccgaaaaagg ctgagatctg gtgtctcagt cttttatttc ttgcgttttg caaaatctac
    19141 aaatctaaat ttttctaact tatggcgact ttcggtaaac tgaaattggc gtccgtcttg
    19201 gagatagact tttgatttaa tcgaaacgac ataagggtct ttgccaatgt ccatgagaat
    19261 cttgtctcgg tcgcttgagt ggtcaatggt gatttccttc tgagcataat caataaggag
    19321 tttgaggcca ttttctatat aagaatagat agactgctca gcaatttggc gagtgagatt
    19381 tggaattagt tccatatcca gatagtctgt atccagaacg gataccagat catccaccac
    19441 acgctggcgg accaccttcc aaaccatccg aaactctggg aaaccggtta tcagtgagga
    19501 ttttttatca ataataatct tgtccagact gaccacgttg gttttagagc gcagtccaag
    19561 ttctttaact agttcttggt agctggttag gttggataca gggaaattga cggtttcttc
    19621 tttgacgact tgagaacctt gccctcttat ctttttgatc aatccttcct cttggaggag
    19681 agacagggcc tttcggacgg tatcacgact cacttgatat tgctccataa ggtcgtgctc
    19741 gctaggaagg aaatctccga cagcgtaagt ctcgttttga atggtttctt ggatttgctt
    19801 aaataattgt tggtatttct tcattttgcc tgcttaaata ggtttttagt ctagtttaat
    19861 gaacacctgt atctatttta ccatacaagt gctagaaaat ttacaaaaaa acaccctttt
    19921 tataccaaac aagttgcaga caagtttggt atcgtttaca atatacttat caaatcaaac
    19981 ttgctttgac aagtataagg agaatcaaat gggaaaattt gaacaagaag ccaaagatct
    20041 gcttcaggca attggaggca aagaaaatgt gactgccgtc acccactgtg cgacacggat
    20101 gcgctttgtt ttaggagatg ataagaaggc taatgttaaa gctatcgagt caattccagc
    20161 tgttaaagga acttttacaa atgcaggtca atttcaggta atcattggaa atgacgtgcc
    20221 catcttttat aatgatttta cagccgtttc aggtattgag ggtgtttcca aagaagcagc
    20281 caagtctgca gctaagagta atcaaaacgt ggtccaacgt gttatgacca ctctggcgga
    20341 gatttttact ccgattattc cagccttgat agtcggagga ttgatcctcg gtttccgtaa
    20401 tgtcttggaa ggtgtccatt ggtcgatgtt ggatggcaag accatcacag aatcctctca
    20461 gttttgggca ggtgtcaatc acttcctctg gttgcctggt gaagctatct tccagttctt
    20521 accagtaggg attacttggt ctgtttctcg taagatggga accagccaaa ttttgggaat
    20581 tgttctcgga atctgtttgg tatcgcctca gttgctcaat gcctatgcgg ttgcttcaac
    20641 gccagcagct gatatcgcgg caaactgggt ttggaatttt ggctatttta ctgttaatcg
    20701 tatcggttac caagcccaag ttatcccagc cttgcttgca ggtttgagtc tgtcttatct
    20761 tgaaatcttc tggcgcaagc atatcccaga agtcatttct atgatttttg tacctttctt
    20821 gtcattgatt ccagccttga ttttggctca tactgttttg ggaccaatcg gttggacaat
    20881 tggacaagga ctttcatcag ttgtcttggc aggtttaact ggtccagtta aatggctctt
    20941 cggtgcaatt tttggtgccc tctacgctcc atttgtcatc acaggtctgc accatatgac
    21001 caatgccatt gatacacaat tgattgcgga tgctggtggc actgccctat ggccaatgat
    21061 tgctctttct aatattgctc aaggctcagc cgtgtttgtc tattatttca tgcatcgcca
    21121 tgatgagcgt gaggctcagg tttcacttcc tgcaaccatt tcagcctatc tcggtgttac
    21181 agaaccagct ctttttgggg ttaacgtaaa atatatttat ccatttgttg ctgggatgac
    21241 tggttcagcc cttgcaggca tgttatccgt tacttttaat gtaactgcgg cttctattgg
    21301 tatcggtggt ttgccaggta ttctctctat tcaacctcaa tacatgctgc catttgcagg
    21361 aactatgcta gttgcgattg ttgttccaat gctcttgact ttcttcttcc gcaaggctgg
    21421 tctctttaca aaaacagagg gcgatacgaa cttgcaggca gaattcgttg ctcaagaaga
    21481 agcagaattt gtgaaccatg aaccagtaga acttacttcg gtagaaatta tcagcccact
    21541 aactggccaa gtgaaagaat tgagtcaagc gacggatcct atttttgcat caggtgtcat
    21601 ggggcaaggt ctagtcattg aaccaagcca aggtgagttg acctctccag ttaatgggac
    21661 agtgacggtt cttttcccta ccaagcatgc catcggcatt gtctctgacg agggagttga
    21721 attgctcatc cacatcggta tggatacagt aggtcttgat ggcaaaggtt ttgaaagtct
    21781 tgtagtccaa ggagatcacg ttacagttgg tcagcaactg attcgttttg atatggatgt
    21841 cattaaggct gcaggtctgg tgacagaaac tcctgttatc atcaccaacc aagatgctta
    21901 tacagcgact attcccggaa cttatccgac aacgatccaa gctggagcat ctctcatggt
    21961 cgctacacga atctaatact cttcgaaaat ctcttcaaac cacgtcagct ctatctgcaa
    22021 cctcaaaata gtgttttgag caacctgtgg ctagcttcct agtttgttct ttgattttca
    22081 ttgagtataa ttgaaatagc acaaataggg acggaagact gcttcctccc ttttatcaga
    22141 aaaggagaaa cagatgacac ttgataaagg aaaagtagtc tatcaaatct atccaaaatc
    22201 ttacaaagac accactgaaa acggtattgg ggatttccgt gggattatcg aaaaaattcc
    22261 ctatttagcc aaactaggtg tggatatggt ctggctcaat ccattctatc caagccctca
    22321 acgggataat ggttacgata tttcagatta tatggcagtg gatcctcttt ttggtgatat
    22381 ggctgatttt gaggaaatgg tgtgtgtcgg taaagagcac aagattgact ttatgctgga
    22441 catggtactt aatcattgtt cgacagagca tgaatggttt cagaaagccc tagctggtga
    22501 taagtattat caagactttt tcttcatcca agaccaacca acagattggc agtctaagtt
    22561 tggtggttct gcatggacgc ctttcgggga tactgggaaa tactatcttc acctatttga
    22621 tgagacccag gctgacctta actggcgcaa ttccaatgtc cgtaaggagc ttttcaaggt
    22681 tgttaatttc tggcgcgaca agggtatcaa aggtttccga tttgatgtga tcaatttgat
    22741 cggtaaggac gaggtttcag tggactgtcc tgaaaatgaa gggaagccag cttatacaga
    22801 caaacccatc gttcataact atttgcgtat gatgaaccaa gccacttttg gatctgacga
    22861 tagctttatg acagttgggg aaatgtcttc taccaccatg gaaaactgtg tcctctattc
    22921 gtcgcctgat cgtcaggaat tatccatgac ctttaatttt catcacctca aggtggacta
    22981 taaggatgga caaaagtgga ccttggctcc ctttgatttt gaagagttga agagtcttta
    23041 ccatagttgg ggtaaggaaa tgagtgataa agacggttgg agtgccctct tttggaacaa
    23101 tcacgatcaa ccacgtgcct tgaaccgttt tgtcgatatt caaaacttcc gcaaggaagg
    23161 agccaccatg ctagcggcta gcattcacct gtcacgtggg acaccttata tctatatggg
    23221 tgaagaaatc gggatgattg acccagacta tgattctatg gctgattatg tggatgtcga
    23281 atcgcttaat gcctatcaga cgctcttaga agaaggaaag agtcagcaag aagccttcca
    23341 gattattcaa gctaagtcgc gtgataattc acgcattccc atgcagtggg atgcttcgga
    23401 aaatgcagga ttttcaacag gcactccatg gttgaaagct ggtaaatcct ataaatacat
    23461 caatgtagaa aatgaaatcc agggtccgat tttcaccttc tatcaagact tgattcgact
    23521 gcgtaaggaa atgccaatca tttcagaagg aagttacaaa ccagcctttg aagatagcaa
    23581 acaagtctac gcttttgaac gccagtttga ggatcaaaag ttactagtgc tcaataactt
    23641 ttatgctaaa gaagtggaaa tcgacttgcc agcagtctac caaaatggac agattttgat
    23701 atcaaactat gaagatgcag aagtgtctga gaaaattcta ctcaaaccct atcaaacact
    23761 ggctatttat gtaaattaat actcttcgaa aatctcttca aaccgtgtca gttttatctg
    23821 caacctcaaa gcggtgcttt gagcaacctg tggctagctt cctagtttgc tctttgattt
    23881 tcattgagta taaacttagc aaggagacct ctttttcaga aaagcagggt tctttttgct
    23941 gtctattcca tccctgaaag tgtagaacaa actggtcagg gtggctagtt tgtggtataa
    24001 tgaaagggat tcaaaaagaa acaggagaaa aatgatggat ttacttttag caattgtatt
    24061 gattgtgcta gcttttctag gaggagctct tggaggaatg tacttggttc gtaagcaaat
    24121 cgaaaaagaa tttgctgaca acccacgttt gaatgctgaa gcagttcgta ctcttttgag
    24181 tgcaaatggt caaaaaccaa gcgaagctaa ggtacaacaa gtttaccacc aaatcatccg
    24241 ccaacaaaag gcagcccttg ctaacaataa aaagaaaaaa taaataagga aaagtctggg
    24301 atgaaagttc cagacttctc actatgttgg ttatggttta gggatgagac tttttccttg
    24361 cattctattg atatttgatt atgattaaga gagaggtagt tgacattcta tcaagctgtc
    24421 ggtcagttcg ttcagtacaa ggaatcataa tgaacgatca atcagaaaaa agactagaaa
    24481 gaagactgta tggataatcg accaattggt tttttggatt cgggtgtcgg gggcttgacc
    24541 gttgtgcgcg agctcatgcg ccagcttccc catgaagaaa tcgtctatat tggagattcg
    24601 gcgcgggcgc cctatggccc ccgtcctgct gagcaaattc gtgaatatac ttggcagctg
    24661 gtcaactttc tcttgaccaa ggatgtcaaa atgattgtca ttgcttgtaa cactgcgact
    24721 gcggtcgtct gggaagaaat caaggctcaa ctagatattc ctgtcttggg tgtaattttg
    24781 ccaggagctt cggcagccat caagtccagt caaggtggga aaatcggagt gattggaacg
    24841 cccatgacgg tacaatcaga catataccgt cagaaaatcc atgatctgga tcccgactta
    24901 caggtggaga gcttggcctg tcccaagttt gctcccttgg ttgagtcagg tgccctgtca
    24961 accagtgtta ccaagaaggt ggtctatgaa accctgcgtc ccttggttgg aaaggtggat
    25021 agcctgattt tgggctgtac tcattatcca ctccttcgcc ctattatcca aaatgtgatg
    25081 gggccaaagg ttcagctcat cgatagtggg gcagagtgcg tacgggatat ctcagtctta
    25141 ctcaattatt ttgaaatcaa tcgtggtcgc gatgctggac cactccatca ccgtttttac
    25201 acaacagcca gtagccaaag ttttgcacaa attggtgaag aatggctgga aaaagagatt
    25261 catgtggagc atgtagaatt atgacaaata aaatttatga atataaggat gaccaggact
    25321 ggtatgttgg gtcttatagt atttttggtg gcgttaacag tttgagcgac tatcagacag
    25381 attttcctct gtttgaattc tccaaaatat ttggagatga agagtatggt ttcccgcttt
    25441 cagttactgt tttacgctat ggttctacct accgtttgtt ctcctttgtg gtagatatgc
    25501 ttaatcaaga aatgggacga aacttggaag ttattcaacg tcatggggcc ctgctcttgg
    25561 ttgaaaatgg gcaactcttg tatgtagaat tgcctaaaga aggggtcaat gttcatgatt
    25621 tctttgagac aagcaaagtc agagaaacct tgttgattgc gactcgtaac gaaggtaaaa
    25681 ccaaggaatt ccgagctatc tttgataagt taggctacga tgtggaaaat cttaatgact
    25741 accctgacct gcctgaagta gcagaaacag gtatgacctt tgaggaaaat gcccgcctta
    25801 aggcagaaac catttctcaa ttaacgggca agatggtttt ggcagatgat tctggtctca
    25861 aagtcgatgt ccttggtggc ttaccaggcg tctggtcagc tcgtttcgca ggtgtgggag
    25921 caactgaccg tgaaaataat gccaaactct tgcacgaatt ggccatggtc tttgaactca
    25981 aggaccgctc ggctcagttc cacacaaccc tagtcgtagc cagcccaaat aaggaaagtt
    26041 tagttgttga agcagactgg tcaggttata ttaactttga acctaagggt gaaaatggct
    26101 ttggctatga tcccctcttc cttgtaggag agacaggtga gtcatcagct gaattaaccc
    26161 tggaagaaaa aaatagtcaa tctcaccgtg ccttagccgt taagaaactt ttggaggtat
    26221 ttccatcatg gcaaagcaaa ccatcattgt aatgagcgat tcccatggcg atagcttgat
    26281 tgtggaagaa gtccgtgatc gctatgtggg caaagtcgat gccgtttttc ataacggcga
    26341 ttctgaacta cgtccggatt ctccactttg ggagggcatc cgcgttgtta aagggaacat
    26401 ggacttctac gccggctacc cagaacgtct ggtgactgag cttggttcga ccaagattat
    26461 ccaaactcat ggtcacttgt ttgacatcaa tttcaacttt caaaagttgg actactgggc
    26521 tcaggaggaa gaggccgcta tctgcctcta tggtcacttg catgtgccaa gtgcttggtt
    26581 ggaaggcaag atcctctttc taaatccagg ctctatcagt caaccacgag gtaccatcag
    26641 agaatgtctc tatgctcgtg tggagattga tgatagttac ttcaaagtgg actttttgac
    26701 acgagatcac gaggtgtatc caggtttgtc caaggagttt agccgatgat tgccaaggag
    26761 tttgagactt tcttgttggg gcaggaggaa acttttttga cccctgctaa aaatctagct
    26821 gtgttgattg atactcacaa tgcggatcat gcgaccctct tgctcagtca gatgacctat
    26881 acccgtgttc ccgttgtgac agatgaaaaa cagtttgttg ggacgattgg actcagagat
    26941 attatggctt atcagatgga gcatgacttg agccaagaaa tcatggcgga tacggatatc
    27001 gttcatatga caaaaacgga cgtagcggtt gtttcgcctg atttcaccat tacggaggtc
    27061 ttgcacaagc tagtagatga gtccttctta ccggttgtgg atgcagaggg tattttccaa
    27121 gggattatta cgcgcaagtc catcctcaag gccgttaatg ccctcttgca tgactttagt
    27181 aaggaatatg agattcgatg ccaatgagag acaggatttc agccttttta gaggaaaagc
    27241 agggcttgtc tgtcaattcc aagcagtcct ataagtatga tttggagcaa tttttagaca
    27301 tggtaggtga gcggatttct gagaccagtc tcaagattta ccaagcccag ctagccaatc
    27361 taaaaatcag cgcccagaag cgaaagattt cggcctgtaa ccaatttcta tactttctct
    27421 atcaaaaagg agaggtggac agcttttacc gcttggaatt agccaaacaa gctgaaaaga
    27481 agacggaaaa gccagagatt ctatacctag actctttttg gcaggaaagc gaccatccag
    27541 agggccgctt gctagcgctc ttaatcctag aaatggggct cttgcccagt gagattttag
    27601 ccatcaaggt tgcggacatc aatctggatt ttcaggtgtt gcgaatcagc aaggcttccc
    27661 aacggaggat tgtcaccatt cccacggcct tgctttcaga attggaaccc ttgatggggc
    27721 agacctatct ttttgaaaga ggagggaaac cctattctcg tcagtgggcc tttcgtcagt
    27781 tagaatcttt tgtcaaggag aaaggttttc catccttatc agctcaagtc ttacgtgaac
    27841 agtttattct aagacaaata gaaaacaagg tcgatttgta cgaaattgca aaaaaattag
    27901 gattaaaaac agtcctgacc ttagaaaaat atagataatg gatattaaat taaaagattt
    27961 tgaaggaccc ctggacttac tcttgcatct ggtttctaag taccagatgg atatctacga
    28021 tgtgcccatt acggaagtca tcgaacagta tctagcctat gtctcaaccc tgcaggccat
    28081 gcgtctggaa gtgacgggtg agtacatggt catggctagt cagctcatgc tgattaagag
    28141 tcgtaaactc cttccgaagg tagcagaagt gacagacttg ggggatgacc tggagcagga
    28201 cctcctctct caaatcgaag aatatcgcaa gttcaagctc ttgggtgagc acttggaagc
    28261 caagcaccaa gaacgggccc agtattattc caaagcgccg acagagttga tttacgaaga
    28321 tgcggagctt gtgcatgaca agacgaccat tgacctcttt ttggcttttt caaatatcct
    28381 agccaagaaa aaagaggagt ttgcacaaaa tcacacgact atcttgcggg atgagtataa
    28441 gattgaggac atgatgatta ttgtgaaaga atccttgatt ggacgagatc aattgcgctt
    28501 gcaggatttg ttcaaggaag cccagaatgt ccaagaggtc atcaccctct ttttggcaac
    28561 cctagagtta atcaaaaccc aggagctgat cctcgtgcaa gaggagagtt ttggagatat
    28621 ctatctcatg gaaaagaagg aagaaagtca agtgcctcaa agctagactt gatagagagg
    28681 aaagatgagt actttagcaa aaatagaagc gctcttgttt gtagcgggtg aagatgggat
    28741 tcgggtccgc cagttagctg aactcctctc tctgccaccg acaggcatcc agcaaagttt
    28801 aggaaaatta gcccagaagt atgaaaagga cccagattcc agtttggctt tgattgagac
    28861 aagtggtgct tatagattgg tgaccaagcc tcaatttgca gagattttga aggaatactc
    28921 taaggcgcct atcaaccaga gcttgtctcg ggctgccctt gagaccttgt ccattattgc
    28981 ctacaaacag ccgattacgc ggatagaaat tgatgccatc cgtggggtta actcgagtgg
    29041 agccttggca aagttgcaag ctttggacct gataaaggaa gacgggaaaa aggaagtatt
    29101 ggggcgcccc aacctctatg tgactacgga ttatttccta gattacatgg ggataaacca
    29161 tttagaagaa ttaccagtga ttgatgagct tgagattcaa gcccaagaaa gccaattatt
    29221 tggtgaaagg atagaagaag atgagaatca ataagtatat tgcccacgca ggtgtggcca
    29281 gtaggagaaa agcagaagag ctgatcaagc aaggtttggt gacagttaac ggccaagtgg
    29341 tgcgtgaact agcaaccact atcaagtcag gcgacaaggt cgaagttgaa ggtcaaccta
    29401 tctacaacga agaaaaggtc tattatctgc ttaacaaacc acgcggtgtc atttccagtg
    29461 taacagatga caagggtcgc aagacggttg tcgacctctt gcccaatgtc aaagagcgca
    29521 tttaccctgt gggtcgtttg gactgggata catcaggagt cttgattttg accaatgatg
    29581 gggactttac agacgagatg attcaccctc gtaatgagat tgacaaggtt tatgtcgcgc
    29641 gtgttaaagg tgtggccaat aaggacaatc ttcgcccctt gacccgtggt cttgagattg
    29701 atggtaagaa aaccaagcca gctgtttatg aaattctcaa agtggaccca gtcaaaaatc
    29761 gctctgtggt gcagttgacc atccatgaag ggcgtaacca tcaggttaaa aagatgtttg
    29821 aagctgttgg tctccaagta gataagttgt ctcggactcg tttcggacac ctagacttga
    29881 caggactccg tccaggagaa tcccgtcgtc ttaataaaaa agaaatcagc caactacaca
    29941 ccatggctgt aactaagaaa taatgaaacg aattttaata gcgcttgtgc gcttttacca
    30001 acgttttatc tcaccagtct ttccaccctc ttgtcgcttt gagctgactt gttccaacta
    30061 catgattcag gctattgaaa aacatggttt taagggggta ttgatgggct tggctcggat
    30121 tttacgttgt catccctggt cgaaaacagg taaggacccc gttccagacc acttttccct
    30181 taaacgaaat caagaagggg aatgaggtgg ggtaaataga tttcaaaatg ataaaaacgc
    30241 atcctatcag gtttgagtga acttgatagg atgcgtttta gaatgtcaaa attttatact
    30301 cttcgaaaat ctcttcaaac cgcatcagct ttcatctgca acctcaaaac agtgttttga
    30361 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt aaattgagtt
    30421 tgaagtggct tatttcaaag ctttttgtat gtcttcaatc atgagttttg ttgattcaag
    30481 tccgcctccg cttagatacc agaggtctgg tgttagttgg ataatcttac catttttagc
    30541 agcaggtgtt tcagcgataa gggcattttc taggacaccg tcgttgctag agttgtcccc
    30601 accgatggca agggtacggt tgatgacaaa gaggatgtca gggttgattt ctttgacact
    30661 ttcaaagctg acttcttgtc cgtggcgtga gtcttcaaat tttgtatcag ttggtttgaa
    30721 tttcaaggtt tggtacaaga aagagaaacg agatttggca ccaaaggctg ccatttttcc
    30781 ttcattaagg aggatcgcaa gggctttttt gtcagagctt tcatttttag tagcgacttc
    30841 ttggatgctc ttgtctagct tggccaattc ttccttggct ttttgtgtac tagtttcgcc
    30901 gaaggcactt gctaaggatt cgatattagc cttggtagaa gtccagtagt catccttgct
    30961 tgcttggaag agaacggttg gggcgatttc tttgaatttg tctacaaatt tttgtgtacg
    31021 tggtgaagcg ataatcaaat caggctcaag ggcggcgata gcttctaaat caggttcttt
    31081 catagaacca acatttttga cagttcccac taggtctttt agataagtcg gaacagtttt
    31141 tgtaggcatt ccgacgatat ttttttcaaa tcctaaagcg cgaatagtat ccgcagcgcc
    31201 gaggtcaaag gtcacaatct tttcaggaac tttggaaagt ttgacctcgt ccagtgaact
    31261 tttaatggtt acctctgttg gagcagagct actggtctct gtctgactag tgcttgagtt
    31321 tgtactacat gcaccaagta ggagcaagaa gctggccact agggcagtga aataaagttt
    31381 aagggatgtt ttcataattt ctccttttta aaatgtgata acgatttagg gagtctctta
    31441 atcttattga ctaagagact gaaggttctc taacttgagc ttttatgtta ctagctatag
    31501 atacagatct ttttgttatt gatatcagct agcgtgatgg gaatctcata aagttgactg
    31561 agcaggtcag cctgcatgat ttgatcggtt cttcccttgc taaagacctg gccgtccttg
    31621 aaggcgacaa tttcatctgc atactgactg gccatgttga tatcgtggag gacgatgata
    31681 atggtcttgc cgagttcctc caccagtcgt cgaagaatct gcatcatgct gacgctttgc
    31741 ttgatatcga gattgttgag tggttcgtcc agcaagataa agtccgtatc ctgggccagt
    31801 accatagcga taaagacgcg ctggagttgc ccccctgaca ggctattgat gtagcggtct
    31861 tttaagttgg tcagttccaa atagttcaga gtttctcgga ttttttccca gtcttctgat
    31921 ctaagtcgac ctcggctgta gggaaaacgt ccaaaactga ccagttcttc aacagtcaat
    31981 ttggcttggt aattgatttt ctgttttagg atggttagtt cttgggccag ttcttgcgaa
    32041 ttccagctct cgatttcacg tcctttgata ctgagaactc cctgatcttt cttggttagt
    32101 ctgctcatga tggagaggag agtcgatttt ccagcaccat ttggaccaat aaaggctgtc
    32161 agtttttgag gactgacttc aagcgaaatg ccttgcaaaa tatcctgttt ttgaatggat
    32221 ttgtcaatgt tttccagttt cactgacgag ccctcctata tagtaagata aagaataaga
    32281 agccacccac actctcaatg atcatactga tacgaatttc cagtgcaaag actcgttcaa
    32341 tcaaggcttg ccccaaggtt aagctaataa atccaaccag aatggccact ataaagagta
    32401 acttgtgctg atagtctttg acaatcaggt aggtgaggtt ggccagcata aagccgaaga
    32461 aggccatagg tcctaccaag gcagtggccg ttgaggtcaa aagcacgatt ccccagagga
    32521 gctctttctg ttctttttca acatcgagtc ccaatatctg agccgtttct ctttgcaggt
    32581 gcaagacatc tagaacgact gcttttcgaa agaaaaagat tgtcaaagcg aggatgatca
    32641 gagaaccgat ggctaggatg gaagtgttaa gatgttgaaa ggaggcaaaa agactatttt
    32701 gcagtttatc gtattcgttt ggatccatta ggacttgaag gaaggtgctg atatttcgaa
    32761 agagacttct gagcgctaga cagatcagca ggatgaagac caggtcttgc ttcatcagtg
    32821 tcttcaagta accttgtaag gcgagaaaga agagggactg gacaagaagt aagactagga
    32881 attctaagat aggggatttg ccaagttgaa gaaacttgct ttcaaaaacc agtagtaggg
    32941 tttgtagtag gacgtagaag gattcaattc ccaaaatact aggcgtcagg aagcgatttt
    33001 ccgtcagggt ttgaaaacta atggtcgaaa tcccagtcgc gatggctacc aagagataaa
    33061 cgatgatctt ttgggaacgc aacttccaag caaaggctga caagtgagtg atgggccaaa
    33121 agtagagaag acaagctccg atggcaagaa taatgagaat ccagaagagc ttggtatgtt
    33181 tgcttttagt ctgcatcttt tcgtccccct ctccagagaa gtaggataaa gacgagacta
    33241 ccgatgattc ctagcaagag actgacagac aactcatagg gcctaatcag aactcgggat
    33301 aggatatcgc aagccagaac tagattggca ccaaccagtg cgaccatgag tttggtttga
    33361 cttagattat ctccatagcg cttgcgaaca agattgggaa cgataactcc gagaaatggt
    33421 aagccaccca cggtaatcat ggtgacgctt gtcgttagcg ccaccagaaa gagggccagt
    33481 ttttcaagta gggagtagga aatccccaaa ctctcgctgg tttctttccc tagattcatg
    33541 atggtgaagg tttgggataa tttccaaacg gttatcagga tgatgaggcc taagaagagc
    33601 cactcatact gatgggtctg aatcatggag aaggagccct gggtccaggc agtcatactc
    33661 tgaaccagat tgaaacgata ggcgataact tctgtgactg agccgataat cccgctatag
    33721 atgatcccaa tcagaggcaa catccacctt tcctttacag taaaaatggt cataaaggct
    33781 aggaagaaga gggtgaatac gatggatgaa ataaaagcga agagcatctt ttgggtcaga
    33841 ctagccgatg gaaagacaaa aaggctcagc accattccca gtttggcggc ttcagtcgtt
    33901 ccaactgtac tcggtgcagc aaactgattt tgggtaatag tctgcatgag aaggcctgcc
    33961 atactcatac tagaggcagt caggagaata ctgatagttc ttgggagacg ggactcttga
    34021 aagaggagcc aggtctgctg gtcgaaatca aatagctttc cccatgaaaa atcactggtc
    34081 ccaatgctaa tagagagaaa gactaggagt agaagtaagc caattaaata atgagaaagt
    34141 ttcatacccc gtcctttcat gtagatttgg tatcgaaaga tacctgcgga tataaatgta
    34201 acattatttt tctaatctgt caataaaatt tctgacaatt taataaatac aacaaggaga
    34261 gagcaacaag actttctcct ttgttatcct attctaaaat gtttttacct taatctgata
    34321 aaataatatc ttcgagggag tagctagccg tccaatcaag atattgttta gcttttgaag
    34381 catctgctag gacactggct gggtcactag cacgtcgagc aacaatctcg tgtgggattt
    34441 tttaatttag taattcttca gcagttttaa agatttcttt gatagtatag ccttttttag
    34501 ttcctaagtt aaagatttga gaagaactgt cttcttgaaa taggtagttc attcctttaa
    34561 catgagccta tgcaaggtcc aagacataaa tgtaatctcg aatacatgaa ccgtcacgtg
    34621 tatcgtagtc atctccaaat atttttaagc tatcatgttg tcccaatgcg gtcttgttga
    34681 tatttggaat gatgtgagtt ggatttttca cacgcagacc gtttgaagca tccatttcag
    34741 ccccagcaac attaaagtaa cggaaaataa catatttcca gtcgtagcga ttggccatcc
    34801 agtaaatcat tcgttcgccc atcagttttg tctctgcata agggttgaca gggtcgagca
    34861 gggtatcttc agtcaccggc ttgtcaatac agttatttcc atagagagaa gcagtcgaag
    34921 agaacatgat tttttgaatg ccaacttcag ataagacttt gagaacttgg tccataccag
    34981 caacgttggc agtgaagtat ttacttggat tttcaatact ttcgctcaca acaatttcac
    35041 ctgcacaatg gaggacagca tcaatctgat tttcttctaa gtaagccttt aaggcgctag
    35101 catcataaac atccagttct ttaaagctag cacgactatc cacagccgct cgatttcctg
    35161 tggagagatt atcgaggaca tgcacctgat agccagcatt taaaagagct ttaacggtat
    35221 gggagccaat gtagctagtc ccacctgtaa caagaattgt tttggtcatg attttttcct
    35281 tttctagttt tgtactatag taaattgaaa taagatatga acaactctat tagaaaagtc
    35341 aaattaattt ctagaaatgt tttagcagct acagcgtact attccaaact caaccaacta
    35401 tatatttaaa gaaagaagaa agggaagtca actattttct gtaaatttca tgaaaaatcc
    35461 aaacaacttt gatggtgtat tgtttttttg tttggaaata aatattcgag ttaattttgg
    35521 aatgtttact agattttgca ctacatgcaa gagaatacta tccttttcta agatagagca
    35581 ggactaagat actaacttag aaatccacct tcccactatc cttctcctat aaaaagtggt
    35641 aaaatggatg aaagaaagaa ggaactgaaa tgacaacatt attttcaaaa attaaagaag
    35701 taacagaact tgctgcagtc tcaggtcatg aagcgcctgt ccgtgcttat cttcgtgaaa
    35761 agttgacacc gcatgtggat gaagtggtga cagatggctt gggtggtatt tttggtatca
    35821 aacattcaga agctgtggat gcaccgcgcg tcttggtcgc ttctcatatg gacgaagttg
    35881 gttttatggt cagcgaaatc aagccagatg gtaccttccg tgtcgtagaa atcggtggct
    35941 ggaaccccat ggtggttagc agccaacgtt tcaaactctt gactcgtgat ggtcatgaaa
    36001 ttcctgtgat ttcaggttct gttcctccgc atttgactcg tggaaagggg ggaccaacca
    36061 tgccagccat tgccgatatc gtttttgatg gtggttttgc ggacaaggct gaggcagaaa
    36121 gttttggcat ccgtcctggt gataccatcg taccagatag ttctgcaatt ttgacagcca
    36181 atgaaaaaaa tatcatctca aaagcttggg ataaccgcta cggtgtcctc atggtaagcg
    36241 agctagctga agctttatta ggtcaaaaac tcggcaatga actctatctg ggttctaacg
    36301 tccaagaaga agttggtctg cgtggcgctc atacctctac aaccaagttt gacccagaag
    36361 tcttcctcgc agttgattgc tcaccagcag gtgatgtcta cggtggtcaa ggcaagattg
    36421 gagatggaac cttgattcgt ttctatgatc caggtcactt gcttctccca gggatgaagg
    36481 atttcctttt gacaacggct gaagaagctg gtatcaagta ccaatactac tgtggtaaag
    36541 gcggaacaga tgcaggtgca gctcatctga aaaatggtgg tgtcccatca acaactatcg
    36601 gtgtctgcgc tcgttatatc cattctcacc aaaccctcta tgcaatggat gacttcctag
    36661 aagcgcaagc tttcttacaa gccttggtga agaaattgga tcgttcaacg gttgatttga
    36721 ttaaacatta ttaaaccata agggaggtgg tagggatggc agaaccaaac ctagaaagcc
    36781 ttataaaaga tctttacaat catgctcgac atgatttgag tgaagattta gttgctgctc
    36841 tcctagagac tactaaaaaa ctgcctacta caaatgagca attgcaggca gttcgtctct
    36901 caggcctggt caatcgtgaa ttgctcctaa atcccaaaca tccagcacct gagttgctca
    36961 acttggctcg ctttatcaaa agagaagaag ccaagtacag aggaactgcg acttctgcac
    37021 ttatgtatga ggaacttttt aaaatgcttt gattccattg tggatcaaag cattttttat
    37081 aagacctatc tcgtgagcgt tcaaatagta gtaacaagga atcatgagaa gtcagccgag
    37141 accatagtag tgaagaaact tctgtaatgg aagtggagtg aagtgaggaa tcgtcaaacg
    37201 gtaggggata ggctgtttga agggtgctac gaaaaagata gggtaaggtg aaattatagc
    37261 ggaatgaaat aagatatgaa caaattgatt gaggaaatca aatgaattta tagaaatctt
    37321 ttagcagtca tggtgtccta ttccagtttc gaaatgctat aaagacgaac aaattgattg
    37381 ggaaattcaa atcgctttct atcaatgttt tagaagatac agtgccctag tccaacttca
    37441 atatactata aaagaacaga tggaagcaat tatgatttac ttctatcttt aaaataaatg
    37501 gtctgatagg aaaaatgtgt cccctcataa aatataggat agtacggatg gaaggctttt
    37561 gtagactgga ggacgaagga gtttagaaac tctcgttaaa agttagttga gccggagtat
    37621 ggtggtgtgg ataattatca aaaattattt ctaaatcgaa atagttgaca gttagaacga
    37681 tgagtgttac aattgtttta ttcatttcga tatcgaaata aattggaggt gttatgaaag
    37741 atggtcattt gctagcccat catattcgtt tgttgaatgg gcggattttt caaaagttac
    37801 tgagtcaaga tcctgaggct ctttataggg gtgaacaggg caagatttta gcggttttat
    37861 ggaatagtga aactggctgc gcaactgcga cagatatcgc gcttgcgact ggacttgcga
    37921 ataatacgct gacgactatg ataaaaaagc tagaggaaca aaagcttgta attgttagtc
    37981 cgtgtggaaa agacaagcgt aagaagtatt tagttttaac ggagttaggc aagtcccaga
    38041 aagaagtggg gcatcgtgtc agtcagaaat tggatactat cttttacaaa ggattttcag
    38101 aggaagaaat tcaccaattt gaaggttttc aagaaagaat tttggcgaat ctgaaagaga
    38161 agggaaatga ggtttagaat atgtcacaac aagtgaaaaa tgctcacaac ctatacatcc
    38221 atgccattca agacggacga gttgctgagg ctcaagccca gtctgtaggg gctacctata
    38281 tccaacattc gacaggtgtt cctgacggga aagaaggatt tgcagccttc tttgcagatt
    38341 tctttgagcg tcatccagag cgtcagatta agattgtccg caccattgag gatggcaatc
    38401 tggtctttgt tcatgttcat caatatctga atggtggaga agctcaatgg gtgacgacgg
    38461 atacttttcg tgcggatgag aatggtcgta ttgttgagca ttgggatgtc attgactact
    38521 atcgaacacc tgaaaatgac caactagatc aaatttttgg agattttgaa atcaaggatt
    38581 tggacaagaa agcagaaaat aaaaagctgg ttcgccgttt cttgacagaa attttccaaa
    38641 atggggagct agagcagtgg agtgattatg tggcagacga tttgattcag cataatcatg
    38701 atattggaca aggaagtgct gcttataaaa actatgtggc tgaatatagt gtcacttttg
    38761 actttgtttt ccaactctta ggacaaggaa actatgtggt tagctatggt cagactcaga
    38821 ttgatggcgt tgcttatgcc cagtacgata tcttccgttt aaagaacggg aaaattgtgg
    38881 agcattggga taataaggaa gtcatgccta aggtagaaga cttgaccaat cgagggaagt
    38941 tttaaatgag gacaaagaat gattgaatac aaaaatgtag cactatgcta cacagaaaag
    39001 gatgtcttga gagatgtcaa cttacagatt gaggatgggg aatttatggt tttagtaggg
    39061 ccttctgggt caggtaagac gaccatgctc aagatgatta accgtctttt ggaaccaact
    39121 gatggaaata tttatatgga tgggaagcgc atcaaagact atgatgagcg tgaacttcgt
    39181 ctttctactg gttatgtttt acaggctatt gctctttttc caaatctaac agttgcggaa
    39241 aatattgctc tcattcctga aatgaagggg tggagcaagg aagaaattac gaagaaaaca
    39301 gaagagcttt tggctaaggt tggtttacca gtagccgagt atgggcatcg cttacctagt
    39361 gaattatctg gtggagaaca gcaacgggtc ggtattgtcc gagctatgat tggtcagccc
    39421 aagattttcc tcatggatga acccttttcg gccttggatg ctatttcgag aaaacagttg
    39481 caggttctga caaaagaatt gcataaagag tttgggatga caacgatttt tgtaacccat
    39541 gatacggatg aagccttgaa gttggcggac cgtattgctg tcttgcagga tggagaaatt
    39601 cgccaggtag cgaatcccga gacaatttta aaagcgcctg caacagactt tgtagcagac
    39661 ttgtttggag gtagtgttca tgactaattt aattgcaact tttcaggatc gttttagtga
    39721 ttggttgaca gctctatctc aacatttgca gttgtcactt ttgaccttgt tactagctat
    39781 tttgcttgcg attcccttgg ctgtttttct tcgctatcat gagaagttgg cggattgggt
    39841 cttacagatt gcagggattt tccagaccat cccgtctctg gccttgttgg gactctttat
    39901 tcccttgatg ggaattggga ctttaccggc attgacagct ctagtgattt atgcgatttt
    39961 tccgatttta caaaatacta ttactgggct gaagggaatt gatccgagtc ttcaagaggc
    40021 tgggattgcc tttgggatga ccagatggga gcgtctcaag aagtttgaaa ttccacttgc
    40081 catgcctgtt atcatgtctg gaattcggac ggcagcggtc ttgattatcg gtacggctac
    40141 cttggcgacc ttgattgggg cagggggact gggttccttt atcctgttgg gaattgaccg
    40201 taataatgcc agtttgattt tgattggggc cctttcttct gcagtgctag ctattgcctt
    40261 taacttccta ctaaaagtaa tggaaaaagc gaaattgcgg acgattttct ctggttttgc
    40321 cttggtggct ttattactgg gtctgtctta tagtccagcc cttttggctc aaaaagagaa
    40381 ggaaaacttg attattgctg ggaaaatagg cccagaacca gaaattttgg ctaatatgta
    40441 taaattgctg attgaagaaa ataccagcat gactgcgact gttaaaccga attttgggac
    40501 gacaagtttc ctttatgaag ctctgaaaaa aggtgatatt gacatttatc ctgaatttac
    40561 cggtacggtg actgaaagtt tgcttcaacc atcacccaag gtgagtcatg agccagagca
    40621 ggtttatcaa gtggcgcgtg atagcattgc caagcaggat catctagcct atctcaaacc
    40681 tatgtcttat caaaatacct atgctgtagc tgttccgaaa aagattgcgc aagaatatgg
    40741 cttgaagacc atttcggatt tgaaaaaagt ggaagggcag ctgaaggcag gctttacgct
    40801 tgagtttaac gaccgtgaag atggaaataa gggcttgcaa tcaatgtatg gtctcaatct
    40861 caatgtggcg actatgcagc cagctcttcg ttatcaggca attcagtcag gggatattca
    40921 aatcacggat gcctattcga ctgatgcgga attggagcgt tatgatttac aggtcttgga
    40981 agatgacaag caactcttcc caccttatca aggggctcca ctcatgaaag aagctcttct
    41041 caagaaacac ccagagttgg aaagagttct taatacattg gctggtaaga ttacagaaag
    41101 ccagatgagc cagctcaact accaagtcgg tgttgaaggc aagtcagcaa agcaagtagc
    41161 caaggagttt ctccaagaac aaggtttgtt gaagaaatga tgggacagag actttaaaca
    41221 tactgaactc aacttcctta aacgactaga taaaagaatg ctcagacaat ttcgtctggg
    41281 cttttttgat gtgagaatga ctgaatgtca cttaaaatgg aaagaaagag aaaattttca
    41341 tgattttcta aaattttact gtaaagacag ttgactattc ataaaatagg tgtataatat
    41401 tttgtgaact acttaacaaa taagaggttt tagctcatgt cgactaaggt tagaaatctt
    41461 gtgtataggc agttcattat ctaatagagc gttgcgtccg aaagtctatc cagacacggc
    41521 tctttaaaaa caaaaggaga aatgatgcat acttatttgc aaaagaaaat tgaaaatatc
    41581 aaaacaaccc taggtgaaat gtcaggtggt taccgtcgta tggttgcggc tatggctgat
    41641 ttaggatttt caggaactat gaaggctatc tgggatgacc tctttgccca tcgtagtttt
    41701 gcccagtgga tttatttgct ggttttagga agttttcctc tctggctgga gttggtttac
    41761 gaacatcgta ttgttgactg gattgggatg atttgtagct tgacagggat tatctgtgta
    41821 atctttgtat cggaaggtcg agcaagtaat tatctttttg gcttgattaa ctctgttatt
    41881 taccttattt tggccctaca gaaaggcttt tatggtgagg tgctgacgac actttacttc
    41941 acagtcatgc agccaattgg acttctagtt tggatttatc aggcacagtt taagaaggaa
    42001 aagcaggagt ttgtcgcgcg taaactggac ggcaagggct ggacaaagta tctttccatt
    42061 agtgtgcttt ggtggttggc ctttggcttc atttatcagt ctattggtgc caatcgtccc
    42121 tatcgtgatt caatcacaga tgcaaccaat ggggtagggc aaatcctcat gacagctgtt
    42181 taccgtgaac agtggatatt ctgggcggct accaatgttt tttcaatcta tctctggtgg
    42241 ggagaaagcc tgcaaattca agggaaatat ctaatttatc tcattaacag tctagttggt
    42301 tggtatcaat ggagcaaggc agctaagcag aatactgatt tacttaacta ggaaaagatg
    42361 tttgaaagtg ctgttttgag atttcgatta aaacagatat agttgataat caaggattta
    42421 tagtatgaaa aagaggatcg gcgggtcctc ttttgttgtt gaaaagataa aaaactcagt
    42481 aacctagaaa taagacaact gagctttact ctatattcaa tttttaggaa tgagaaggtc
    42541 tagataaaat tggacaactt cctggcctat gaaatcttga ccttttttga gccaccaggt
    42601 caatgtctcg ataaagttgg acacgaccaa gtgttggagg taagaagtag gcatattagg
    42661 gtgggcttct tttaaattat cagctagcac ggaatagaca tggtgttcta gctctttatg
    42721 gagttgacgg aggaagtagt catttttgga aaatagcaga ctggtgatat ggtcttggtt
    42781 tttctgaaaa tggagaaaga ggtgggcgag gtagtcctcg gttgaaatgg cttgctctct
    42841 ttcaaaaaga tgatggaaga ggtagcggca gagctggtcc agaagaagct ccttactttc
    42901 atagtgacag taaaaggtgg atcttcccac atctgcgaga tcaatgatat cctgaacagt
    42961 agtggcctcg tagcccttag cattcaaaag ttgtataaaa gcttgataga tggctttttt
    43021 ggttttgctg atacggcggt caatgttagt catatggaca cttaaggcaa attgttcaga
    43081 actgaataaa gctgacgttt tgcttctatc ctttctttga gttttagtgg ataatgataa
    43141 tgaacaaggt gttcataaat ctattataac aaaggaatga gaaatatgaa ggcaaaatat
    43201 gctgtttggg tggctttttt cttaaatttg acttatgcca ttgttgagtt tattgcaggt
    43261 ggagtatttg gttctagcgc tgttcttgct gactctgtgc atgacttggg agatgcgatt
    43321 gcaattggaa tatcagcttt tctagaaaca atctccaatc gtgaagaaga caatcagtac
    43381 accttgggct ataagcggtt tagcctgcta ggagccttgg taacagctgt gattctcgta
    43441 acgggctctg ttctagtcat tttggaaaat gtcacgaaga ttttgcatcc gcaaccagtc
    43501 aatgatgagg ggattctctg gttaggaatt attgcgatta ctatcaatct gttagcgagt
    43561 ctggtggttg gtaagggaaa gacaaagaat gagtctattc tgagtttgca ttttctggaa
    43621 gatacgctag ggtgggtagc tgttatcctg atggcgattg ttcttcgatt tacggactgg
    43681 tatatcctag atcctctttt gtcccttgtc atttctttct ttattctttc aaaagccctt
    43741 ccacgttttt ggtctacact caagattttc ttggatgctg tgccagaagg tcttgatatc
    43801 aagcaagtaa agagtggcct ggagcgattg gacaatgtgg ccagccttaa tcagcttaat
    43861 ctctggacta tggatgcttt ggaaaaaaat gccattgtac atgtttgtct aaaagaaatg
    43921 gaacatatgg aaacttgtaa agagtctatt cgaattttcc taaaagattg tggttttcaa
    43981 aatattacca ttgaaattga tgctgaccta gaaactcacc aaacccataa gcgaaaggtg
    44041 tgtgacttgg aacggagtta tgagcatcaa cattagaaaa aagtgaaaaa tacttgggta
    44101 ctatcttatt tggaatagag taatttcttt attatttaaa tatttcaaaa attggtaaga
    44161 gaagagcatt gtataaactc cagatatatg attgttaatg ataaaaattt ttcgattaga
    44221 tacaaaatgc ttgacttgga gtcaactcaa agttatataa taagataagt gagttagaat
    44281 agcgtgaatt cagtgaatga aatgagagga ggttagcgtg tgaatattaa atctgccagt
    44341 gatttgttgg gaatttcagc ggatacgatt cggtattatg aacgggttgg tcttgtgcca
    44401 ccgattactc gtactgctac tgggattcgt gattttcaag atcaggatat cgaagcgctg
    44461 gaatttatta agtgttttcg ttcggcgggt gtctctgtag atagtttagt tgactatatg
    44521 tcgctctacc aaaagggaga tgaaacgaga gaggagaggc ttggtatttt agaagaggaa
    44581 aagcaaaaat tagaggagcg cttgtctcag ctacagacag ctttaaatcg tttaaatctc
    44641 aaaattaaac tttataagga aggaaaattt taaatgaaat cagcagtata tacaaaggca
    44701 ggtcaggttg gacttgctag cattgaacgt ccgcaaataa tagaagcgga tgatgtgatt
    44761 attcgtgtgg ttcgtgcgtg cgtttgtggt tcagatttat ggaggtaccg taatccagaa
    44821 acgaaagctg gacataaaaa tagtggacac gaagcgattg ggattgttga agaagctggg
    44881 gaagccatta cgacggtgaa accaggtgat tttgtgattg tcccttttac acatggatgt
    44941 ggtgagtgtg atgcctgtct tgctggattt gacggttctt gcgacaatca tattggtaat
    45001 aatttggggg gtgattttca ggcagaatat attcgcttcc actatgcaaa ctgggcgctg
    45061 gttaaaatcc ctggtcaacc ttctgattat acagaaggga tgctcaagtc ccttttgact
    45121 cttgcagatg tcatgccgac aggctatcat gcagcgcgtg ttgcaaatgt tcaaaaaggg
    45181 gacaaggttg ttgttatcgg tgatggggct gttggtcaat gtgctgtcat cgcggctaag
    45241 atgcgtggag catcacaaat tatccttatg agccgtcatg aagaccgtca aaagatggct
    45301 atggagtcag gtgcgacagc tgttgttgca gaacgtggtc aagaaggaat taccaaggtg
    45361 cgtgaaatcc tcggcggagg agcagacgca gcacttgaat gtgttggtac ggaggctgct
    45421 atagaacagg cgctaggtgt tcttcataat ggagggcgta tgggctttgt aggagtccca
    45481 cactataata atcgtgctct tggttcgaca tttatgcaaa atatctctgt agcaggtggg
    45541 gcagcttctg ctacaacata cgataagcaa tttttactaa aagccgtcct tgatggtgat
    45601 atcaatccag gtcgcgtctt tacttcaagt tataaactgg aagatatcga ccaagcctat
    45661 aaagatatgg atgaacgtaa gacaattaag tctatgattg taatcgaata aaaaacgaat
    45721 aggagtttta gaactctatt cgttttttat gttatcctat tcttgattta gggtactttc
    45781 tcttaatgtc agtctggttc ccagcatggt caggctagga attttgcgac cgtggaggac
    45841 ttccttgtta agaatatcca tacctgctcg ccccatttct tcagtataaa ctgtaatact
    45901 agagagggga ggatagacct gtttggtcag actggtgtcg ttgaatgaaa tgaggctgac
    45961 gcgatctggc aggctgattc cagcttcttg gagggcacgg agggcaccga tagctaaact
    46021 atcgctggct gcgaaaaatg ctggcggaag ttggtctccc aagctctgaa tggcctcctt
    46081 cattaagtca tagccagact gggcagtaaa tcttccttga aagaccagtt catcatgata
    46141 gattcccctc gcttgactgt agtttttgaa gttttctaga cgcttgtcct gaatgatttc
    46201 ttcttggtct gttgtttcct caagccctgt tagaatcccg atgcggtcca tcccttgact
    46261 gaggaaataa tcgacaacct gtttcatagc agtgtaaaaa tccgtaataa tacaagtatg
    46321 ccccagggaa agtgtatcac tgtctagaaa gaccaggggc ttttggtatt cttcaaaggc
    46381 agaaatctga gctcggctaa attttccgat gcagagaatc ccaatcactt cctcgcttag
    46441 ggtaaaagga tggtcattaa aatagcgcaa gatatcatag tccaactctt gggctctttt
    46501 ttctattcct aggcgaatct ggtagtagta gaggtcgtct agctcccctt gttcgctgac
    46561 ccattggata atggcaatct tttgcttggg cttgtgggac tcgcctgtct tgaggtgttt
    46621 ggtgtagcct agctcttcag caacggttaa aatacggtgt ctggtttctt ctgtaacaga
    46681 taggctctgg tcgcggttga ggacacggga tacggtcgcg attgagacag aggctagctg
    46741 tgcaatgtct tttaaggtag ccataaatcc tccttgatta ggttagtata tcatattttt
    46801 cttcttttta ctgatatttt agtaaaattt tagtaaaaag gattgacctt gggaaattcc
    46861 ttggatacaa tagaaagaaa acgattacac gttaagatgg cttaacggac agtcaaagga
    46921 gaattcatat ggcacaacat cttactactg aagtccttcg caaagacttt cttgctgttt
    46981 ttggtcaaga agcagaccaa accttctttt caccaggccg tattaatttg attggtgaac
    47041 acacagacta caacggtggg cacgtttttc ctgctgctat ttccttggga acttacggtg
    47101 cagctcgtaa gcgtgacgac caagtcttgc gtttctactc agctaacttt gaggacaagg
    47161 gcattatcga agtgcctctc gctgacctca agtttgaaaa agagcacaac tggaccaatt
    47221 atccaaaagg tgtccttcat ttcttgcaag aagctgggca cgtgattgac aaaggttttg
    47281 atttttatgt ttatgggaat atcccaaatg gtgctggctt gtcttcttca gcatccttgg
    47341 agctcttgac aggagtcgtg gcagagcatc tctttgattt aaaattagag cgtctcgatt
    47401 tggttaaaat cggaaaacaa acagaaaaca actttatcgg agtcaactct ggtatcatgg
    47461 accagtttgc tattggtatg ggggccgatc aacgtgctat ttaccttgat accaacacct
    47521 tagagtatga tttggtgcca cttgatttga aggacaatgt cgttgttatc atgaacacca
    47581 acaaacgccg tgaattggcg gactctaaat acaatgaacg tcgtgctgag tgtgaaaaag
    47641 cagtggaaga attgcaagtt gccttggata ttcagaccct gggtgaattg gacgagtggg
    47701 ccgttgacca atatagctat ttgattaaag atgaaaatcg tttgaaacgt gctcgccatg
    47761 ctgtgcttga aaaccaacgt acccttaaag ctcaagcagc ccttcaagca ggtgatttgg
    47821 aaacatttgg tcgtttgatg aatgcgtcac acgtttctct ggagcatgat tatgaagtaa
    47881 ctggtttgga attggatact cttgttcaca cagcttgggc acaagaagga gttctcggtg
    47941 ctcgtatgac aggggctggt tttggtggct gtgccattgc cttggttcaa aaagatactg
    48001 ttgaggcctt taaggaaact gtaggcaaac actacgagga agtagttgga tacgctccaa
    48061 gcttctatat cgctgaagtt gcaggtggca ctcacgtcct tgactagtca aaaggaggct
    48121 ctatggtgac cttagtagat aaatttgtaa cacatgtcat ttctgaaagt tcatttgagg
    48181 aaatggatcg aatctacctg accaatcgtg ttttggcacg agtgggagaa ggtgttttgg
    48241 aagttgagac caatctggat aaattgattg acctcaagga ccagctagtt gaggaagccg
    48301 ttcgattaga gacgattgag gatagtcaga ctgcgcgtga aatccttggt actgaactga
    48361 tggacttggt gactccttgt ccgagtcagg tcaatcgtga cttctgggaa acctatgtcc
    48421 actatcctga gcaagcgata gaggattttt atcaactcag tcagaaaaat gactacatca
    48481 aactcaaggc cattgctaaa aatatcgctt atcgtgttcc atctgattat ggagaacttg
    48541 aaattaccat caatctctct aagcctgaaa aggatccgaa agagattgtg gcagccaagt
    48601 tggtgcaagc tagtaattat cctcagtgtc agctttgtct agagaatgag ggctaccatg
    48661 gtcgagttaa ccacccagct cgtagcaatc accgtattat ccgttttgaa atggttggtc
    48721 aggaatgggg tttccagtat tcgccctatg cttactttaa tgagcattgt atctttttag
    48781 atggccagca tcgtcccatg gccattagtc gtcagagttt tgaacgtctg ttggctatcg
    48841 tagaccagtt tccaggatat tttgctggat ctaatgccga cctgccgatt gtggggggct
    48901 ctattctaac tcatgatcat tatcagggag gccgtcacgt atttcctatg gaattggctc
    48961 ccttgcaaaa ggccttccga tttgctggtt ttgagcaggt caaggctgga attgtcaagt
    49021 ggcccatgtc tgtcctacgt ttgacttcgg attccaaaga ggatttgatc aatttggctg
    49081 ataagatttt gcaggaatgg cgccagtatt cagatcctgc agtgcagatt ttggcagaga
    49141 cagacaggac accgcatcac actatcacac ccattgcccg caaacgcgat ggacagtttg
    49201 agttggactt ggtcttgcga gacaatcaga cttcagcaga gtatcctgat ggtatctatc
    49261 atccccacaa ggatgtccaa catatcaaga aggaaaatat cggcttgatt gaggtcatgg
    49321 gcttggcaat cttgccacca cgtctgaaag aagaagtgga gcaagtcgcg agctatcttg
    49381 taggagaagc tgttacagtt gccgattatc atcaggagtg ggcagaccaa ctcaaatccc
    49441 aacatccaga cctaacggat aaagaaaaag cccttgcaat cgtcaaggac tctgtgggtg
    49501 ctatctttgc gcgtgtactt gaggatgcag gagtctacaa gcagacagaa caagggcaga
    49561 cagcctttat gcgctttgtg gaacatgtcg gaattttact agactaggag ctttctcctt
    49621 gcacagtcct ataaaaagta gtatcatagt gtcgtttgaa atatcaggag gaaacgatga
    49681 aagactttca ttttgacgct atatctgcct ttgaaaatta cgaaattgaa aaaatgagag
    49741 atggtcacgt tgtggtgacg accaaagtag tgaactcgtc gctcaactac tatggcaatg
    49801 cccatggtgg ctatctattc acgctatgtg accaaatcag tggtttggtg gttatctcgc
    49861 tgggacttga tggggtgaca ctccaatcct ctatcaacta ccttaaggca ggaaaactcg
    49921 acgatgtatt gaccattaaa ggagaatgtg tccatcaagg ccgtacaacc tgtgtgatgg
    49981 atgtggatat caccaatcaa gagggcagaa atgtctgcaa agcaaccttt accatgtttg
    50041 tcataggcca aaggtctgag gaaagacggg taaggatata aagaaaggtg agtgggataa
    50101 atttatctca ctcattttta atttatgaga tatgttagaa ggaaatataa aagagagtga
    50161 tgaaatacaa atgtaatagg tacatatatg tggtatacta gttatagtag attttaattg
    50221 cttatatcga gtgagttctc atattagtga ggaattttta aatggaatta cactttaatt
    50281 tagaattagt agaaacctat aaaagtaata gccaaaaggc acgtatctta acggaggatt
    50341 gggtttatcg tcagtcttat taccctaatt gtgggaacaa tcccttaaat cattttgaaa
    50401 ataatcggcc tgtagcagat ttttactgta atcattgtag tgaggagttt gaactaaaga
    50461 gcaaaaaagg aaatttttca tcaacaatca atgatggtgc ttatgcaacg atgatgaagc
    50521 gtgtgcaggc agataataat cctaatttct tttttttaac ttacacaaaa aattttgagg
    50581 taaataactt tcttgtcctt ccgaagcaat ttgttacacc gaaatcgatt attcaaagaa
    50641 aaccacttgc accaactgct agacgagcag gttggattgg ttgtaacatt gatttatcac
    50701 aagtaccttc taaaggaagg atatttcttg tgcaagatgg acaagttaga gatccagaaa
    50761 aagttacaaa agaatttaag caaggtttat ttttaaggaa gagctctctg tcatcaagag
    50821 gttggacaat agaaattcta aattgtatag ataagataga gggttcagaa tttacccttg
    50881 aagatatgta tcgttttgaa agtgacctaa aaaatatctt tgttaagaac aatcatatca
    50941 aagaaaagat taggcaacag cttcaaatat taagagacaa agaaataata gaatttaaag
    51001 gtagaggaaa gtatcggaaa ttatgaaaac gaaacaactt gttgcatcag aagaggtgta
    51061 tgatttctta aaagtcatct ggcctgatta tgaaactgaa agccgttacg ataacctaag
    51121 tttaatcgtc tgtaccttat cagatcccga ttgtgtgaga tggttatctg aaaatatgaa
    51181 atttggtgac gaaaaacaac tagctttgat gaaggaaaaa tatgggtggg aagtaggaga
    51241 taaattgcca gagtggctac atagctccta tcatagatta ttgttaatag gtgaattatt
    51301 ggaaagcaat ctaaaactga aaaagtatac agtagaaatt acagaaactt tatcacgttt
    51361 agtaagtata gaggctgaaa atccagatga agccgaacga cttgtaagag aaaagtataa
    51421 gagttgtgaa attgttcttg atgcagatga ttttcaggac tatgacacta gcatatatga
    51481 ataggtagat gtttttattt tgtcaacaaa aaagaggctc gcacctcttt ttcttatttc
    51541 tttttatgat ttaatacggc attgaggaca atagcgagta ggctggctac gacgattccg
    51601 tttgagaaga acatttggaa ggctgtcggc atgctgacaa agagattact gttgttgaga
    51661 ccgacacctg cagcgattga aacagctgcg ataaggaagt tgtgttcatt gttagcaaag
    51721 tcaacacggg cgaggatttg catcccttga attgatacaa aaccaaacat taccagcatg
    51781 gcaccaccga ggacggagct tggaatgatt tgggcaaggg cgccaaactt aggaagcagt
    51841 ccaaggagaa ccaggaaacc agctgcgtag tagattggca ggcgtttttt gatgcctgac
    51901 aatttaacca aaccaacgtt ttgtgaaaat ccggtgtaag ggaaggtgtt aaagattcct
    51961 ccgagaagta cggccaaacc ttctgcgcgg taaccgttgc gaaggcgcgt gctgtcgatt
    52021 ggatcttttg tgatatcaga caaggctaga taaacaccag ttgactcaac catagacacc
    52081 gttgcgatga tacacatcat gacaatagat gagatttcaa aggttggcat cccaaagtag
    52141 agtggagttg ggacatggac aagtggagct accgcaacag gagagaagtc caccaagccc
    52201 atagtagcag caatggcagt tccaacaacc agaccaatca aaatagagat agacttgata
    52261 aatcctttgg taaagatgtt gatcaagagg ataatcagaa cagtaatagc tgcaagcaag
    52321 agactttgac cagttggctc tggaacgtta tttcccatat ttccaatagc gacagggatc
    52381 aaggttaaac caatcgtggt aataacagat cctgttacga tagatgggaa gagattggct
    52441 acttttgaga agatgcctga aacaagaacc acgtaaatcc cagatgcgat aagggcacca
    52501 aacatagcgc cactaccatg gctttgccca atcataatca agggagcgac cgactggaat
    52561 gcaactccaa gaacgactgg gagtccaatc ccaaagtatt tgttgagttg gagttggagg
    52621 aaggttgcca ccccacacat gaagatatct gtagaaatca ggtaggtcaa ctgctcagct
    52681 gaatagccaa gggctgtcgc aatcatgatg ggaaccagga tagatcctga gtacatggct
    52741 agtaagtgct gcaagcccag aacggctgct tgcgagtgtt tttcttgagt ttgcattaga
    52801 gatctgcctc cttaaatacg acctgaccat tttcaaaacg atccaagcga gcaagtgata
    52861 ggacagggta gcctgctttt tcaagcaaat cacggccatc ttggaaggat ttctcaatca
    52921 cgataccgat agcttggact gtggcaccgg cctgttcgat gatttgaatc aagcctttag
    52981 cagcttggcc attagcaagg aaatcgtcga taatcaaaac cttgtcctct ggtgagagga
    53041 attttccagc gatagaaaca gtgctggtca cctgcttggt aaaggagtag acttgagcag
    53101 ttaagatgcc ttcgttcatg gtgatgttct tagctttttt ggcgaaaatc atgggaacgt
    53161 ttaaggcttc agctgtaaaa acggctgggg caatacccga cgcttcaatg gttacgacct
    53221 tggtaatgcc agtagcagca aatttttccg caaaaacctt accaatctct cgcatcaagc
    53281 taaagtcaac ttggtgggtt aaaaaggaat ctaccttgag gatgttatca cccaagatat
    53341 gcccatcctt gaggatgcgc tcttctaata atttcataag acctcctaaa gtctaaaagt
    53401 taatttactt gttgtttaaa tatttctata gtgatccctt ttgctaatac tatatatttg
    53461 ataaaactat tacgagcgaa gcgagtctta tcaaatattt cccgttgtag tggtatcata
    53521 gacaataatc ttgttattgt ctatgacggg atttttgaga gtaaaatagt tcggggaact
    53581 attttagcct aagcctagaa atgaaagagc taggggctca aaaattaggg atgaaattcc
    53641 ctggattcct gaaattattc acaggataat ttcacctccc gtccgcacta attaagggaa
    53701 atattaaaaa tattcaaaaa agacctactt aatctctaag taagtcccct aaatagacat
    53761 ggcaaaaacg gccatatctc actgctgact tacttattgt taggtgttcc ggcaccttgt
    53821 agaaacgtcg tgccaattca cgacataaac aagtaaaacg atattcaatt ttaaataggc
    53881 ttgagccaat gtttttattt tacactaaat aactttagaa atcaactatt ttgttagtgt
    53941 tttggtttaa aaagcgaaca aaaagaagag agggtgaaca aaaacttcat tgtaagctaa
    54001 catttatact aaatgaaaat caaagagcaa actaggaagc tatccacaac ctcaaaacac
    54061 tgttttgagg ttgtggatag aattgacaga gtcagtatca tatacctacg gtaaggcgac
    54121 gttgacgtgg cttgaagaga ttttcgaaga gtattagaag atttttccat cataaaaggc
    54181 atactatcaa gtttttagac acctgacaat atgccttttt ctaactttaa agacttttcc
    54241 caatttttat tattctactc gctaaatctt aaaaaatagc catctggatc caaaactgca
    54301 aatttatgag gatagatata gggatcactg acacgaaact ttcttttggt caagagacga
    54361 taaataggat agtttgcctc catcactttt tgatagagtt ttggaacatc ctttatgcca
    54421 aaggagagat tgactccacg accaaagggg taggtcagtt cagctagttg atcctttgtt
    54481 ccctcctcta acattagttg acactcttca agagaaagag aaagttttct tctggacgtt
    54541 agtattcaat cctaaaaccc agtaaaccac agtagaagga ccgggactgt tcgatattcg
    54601 atacaagaaa ctcgggaatg accgcattgt agtccatata gaaaatcctt acaagtcaat
    54661 ttccaagaca atcggtgtat ggtcttggcg agcacctgag tcaatcatat cagatttagt
    54721 gaccttgtca gcgatacggt tacttgtgag ccagtagtcg attctccagc ctgtattgtt
    54781 gattttagaa gttttgctgc gttgtgccca ccaagtgtag cgttcaggaa catcgccatg
    54841 aacatggcgg aaggtgtctg taaatccagt tgccaaaagg ttggtaaatc cagcacgttc
    54901 ctcgtcagta aatccaggtg aacggcggtt gctagcagga tttgcaaggt cgatttcatt
    54961 gtgggctacg ttgtagtcac cggtcgcaag gactggtttt tctttgtcta gttcagccaa
    55021 atactcagca tatttaacat cccagacttg gcgttcttcc aagcgtttga gaccgtcacc
    55081 agcgtttgga gtgtaaactt gggttacgaa aaatgcatca aattctagag tgatgatacg
    55141 gccttccaag tccatggtag aaggggcacc gatttctgga aaactgatcg taggcgtaag
    55201 ttctttctta taaaggaaca tggttccagc atagccttta cgggcaggct cttgggaaga
    55261 gcgccatgtg ttttcgtagc ctgggaagag ttcttctaaa atttccacgt gtttctttgt
    55321 aggtcctttg gcagaaagct tggtttcttg gatagcaatg atatcagcat tttcagcgac
    55381 caaggtttgt aggacttctt gggacaattt ggcacgagct gagtcactag ttagggcagc
    55441 gtttagggaa tcaatattcc atgagataag tttcataaag ttaccttttt cattcagatt
    55501 atagatttta ttataccaaa aaaagatcta tttccccaac gtatggtttg aaaaattact
    55561 ctctttcgtt tataattaag aatgatttta tgaaagggag tgaaaatata tgaaattcta
    55621 ctcttatgac tatgtactca gccaaatcgg tcagcaaaat ggtatcatgg ttggctttgg
    55681 gattgttcta ttagctgtga cagttttttt tgctttcaag gcataccatg ataaaaaggg
    55741 aaccgaattt cgtgagttgg tcatgatttc agctctggcc ttatttagct ctgcttttgg
    55801 tcagcatcac gacttatcaa aacaatcaag tttctaacaa taaatttcaa acttcacttc
    55861 atttcatcga ggttgtttcc aaagatttgg gagtagacaa gtcagaagtc tatgttaata
    55921 cttccacaaa cacagatggc gcacttatca aggtgggaga tcgctattat cgtgccctaa
    55981 acggaagtga gccagacaag tacctgttag agaaagtcga attgtataag acagacgcaa
    56041 ttgaactggt ggatgtgaac aaatgacact taattatatc gaaattttaa tcaaactggt
    56101 cttgactctc aaatggctca acaacaatgt tcactttgtg aaacgtttga ttgatggtaa
    56161 gccaactctc cttatcaaaa atgggaatat tgacccagaa gcctgtcgtt cagttggttt
    56221 gtctgcatcg gatgtagccc tcaaacttcg tagccaaggg attttccaga tgaagcaagt
    56281 caaacgagct gtgcaagagc aaaatgggca acttatcgtt gtgcaaatgg gagatgaaaa
    56341 tcctaagtat ccagttgtga ctgacggtgt gattcaagta gatgtcttgg aatcgattgg
    56401 tcgtagcgaa gagtggttgc ttgataacct cagtaaacaa gggcatgaca atgtagccaa
    56461 tatctttatt gctgaatatg acaagggtgc tgttacagtc gtaacttatg aaaaagaaaa
    56521 acctggggtc ttgtactctt cgaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta
    56581 tgtaggttac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcagcct
    56641 gcggctagtt tcctagtttg ctctttgatt ttcattgagt attggcctca ggtttccatt
    56701 tgcaatcaga aagggatttt atgtccatta ttcaaaaact ttggtggttt ttcaagttag
    56761 aaaaacgccg ttatctagtc gggattgtgg ccctggtctt ggtttccgtt ctcaatctca
    56821 ttcctcctat ggttatgggg cgggtcattg atgccatcac atcggggcaa ttaacccagc
    56881 aggacctcct tcttagccta ttttacttgc tacttgcagc ctttggtatg tactatttgc
    56941 gctatgtgtg gcgtatgtat atccttggga cctcttattg cttgggacag atcatgcggt
    57001 ctcgcttgtt taagcatttc acaaaaatgt catcagcctt ttatcaaacc tatcggacgg
    57061 gtgatctgat ggcacacgca accaatgata tcaatgcctt gactcgttta gcaggtggcg
    57121 gtgtcatgtc tgcggtggat gcctctatca cggctctggt gactttgttg accatgctct
    57181 ttagcatctc atggcagatg actcttgttg ccattctccc cctacctttc atggcctatg
    57241 cgactagtcg cctagggaga aagactcata aggcctttgg cgaatcccaa gctgcttttt
    57301 ctgaactcaa taacaaggta caggagtccg tatcaggtat caaagtgacc aagtctttcg
    57361 gttatcaggc agacgagttg aagtcttttc aggcagtcaa tgaattaacc ttccaaaaga
    57421 acctgcaaac catgaaatat gatagtctct ttgaccctat ggttctcgtg tttgttggtt
    57481 cgtcctatgt tttaacgctt ttggttggct ccttgatggt tcaggaaggg cagattacag
    57541 ttgggaatct agtcaccttt atcagctatt tggatatgct ggtctggcct cttatggcca
    57601 tcggcttcct ctttaatact actcagcgag ggaaggtttc ttaccagcgg attgaaaatc
    57661 ttttgtctca ggaatctcct gtacaagacc ctgagtttcc tctggatggt attgaaaatg
    57721 ggcgtttgga gtatgccatt gacagctttg cttttgaaaa tgaggaaaca ctgacggata
    57781 ttcactttag tttggcaaaa gggcaaacac tgggcttggt tgggcagaca ggctctggga
    57841 aaacgtcctt aatcaagctc ctcttgcgtg aatacgatgt ggataagggt gccatttatc
    57901 taaacggtca cgatattcgg gactatcgtc tgacagacct tcgcagtctc atgggctatg
    57961 ttcctcagga ccagtttctc tttgcaactt caatcctaga caatatccgc tttggcaatc
    58021 ctaacttgcc cctttcagcg gtcgaggaag ctactaagct agcccgagtt taccaagata
    58081 ttgtagacat gcctcaagga tttgatacgc tgattggtga aaaaggagtc agtctttctg
    58141 gtggtcaaaa gcaacggttg gctatgagtc gggctatgat tttagaccct gatatcttga
    58201 ttttggatga ttccttatcc gccgtagatg ccaagacaga gtatgcgatt atcgacaacc
    58261 tcaaggagac gcgaaaggac aagacaacca ttatcactgc ccatcgcctc agtgctgttg
    58321 tccatgcaga ttttatttta gttctacaaa atggtcaaat tatcgaacga ggcacgcacg
    58381 aagacttgct agcgatggat ggctggtatg cccaaaccta ccagtctcag cagttagaaa
    58441 tgaaaggaga agaagatgca gaataaacaa gaacaatggg ctgtattgaa gcgcttgatg
    58501 tcttatctca agccttatag actcctgacc tttttggcac tcagttttct cctagcgacg
    58561 acggtcatta aaagtgtcat acccctcgtg gcttcccact ttatcgacca gtatctcagc
    58621 aatcttaacc aactagccgt taccgttttg ctggtctact atggtctcta catcctacaa
    58681 actgtagttc agtatgtagg caatcttctc tttgcgcgcg tgtcttacag tattgttagg
    58741 gatattcgtc gggatgcctt tgccaatatg gagaaactgg gcatgtctta ctttgacaag
    58801 acgccagcag gctctatcgt ctctcgtttg acaaatgaca ccgagactat cagtgatatg
    58861 ttttcgggga ttttatccag ctttatctca gcagttttca tctttctgac aaccctttat
    58921 accatgttgg tattggattt tcgtttgaca gcattagtct tgctctttct ccccttgatt
    58981 ttccttttgg tcaatctcta tcggaaaaaa tcagtgaaaa tcattgagaa aaccagaagt
    59041 ctcttgtcag atatcaatag taagctggca gagaatatcg agggaatcag gattattcag
    59101 gcttttaatc aagagaagcg cctgcaggca gaatttgatg aaatcaacca agaacacttg
    59161 gtctacgcca accgttctgt agccttggat gccctctttt tgagacctgc catgagtttg
    59221 ctgaaacttc taggctatgc agtcttgatg gcctactttg gctaccgtgg tttttctatc
    59281 gggataacgg tcgggaccat gtatgccttt atccagtaca tcaaccgcct ttttgacccc
    59341 ttgattgagg tgacgcaaaa cttttcaact ctgcaaacgg ctatggtttc tgcaggtcgt
    59401 gtctttgccc tgatagacga gaggacctat gaacctcttc aagaaaatgg gcaagccaaa
    59461 gtccaagaag gcaatatccg ttttgaacat gtgtgtttct catatgacgg taaacatccg
    59521 attctggatg acatttcttt ctctgttaat aagggtgaaa ccattgcctt tgtaggtcat
    59581 acaggttcag ggaaatcgtc tattatcaat gtcctcatgc gcttttatga attccagtca
    59641 gggagagttc tcttggatga tgtggatatc agggatttca gtcaagaaga gctgagaaaa
    59701 aacatcggtt tggtcttgca ggaacccttc ctctatcatg gaactattaa gtccaatatc
    59761 gccatgtacc aagaaatcag tgatgatcag gttcaggctg cggcagcctt tgtggatgca
    59821 gattccttta ttcaagaact tcctcagggg tacgactccc ctgtttccga gcgtggttcg
    59881 agcttctcta ctgggcagcg ccagcttctt gcctttgcta gaacagtcgc cagccagcct
    59941 aaaatcctga ttttggatga agcgacagcc aatattgact ctgaaacaga aagcttggtt
    60001 caagcttctc tggcgaagat gagacagggc cgaacaacta ttgctatcgc tcaccgcctt
    60061 tctactattc aagacgccaa ctgcatctat gtcttggata agggacgcat tatcgagagt
    60121 ggaacccatg aggaactctt gactctggga ggaacctatc acaagatgta tagtttgcag
    60181 gcaggggcca tggccgatac tctttgaaaa tctctttaaa ccatgtcagc tttatctgca
    60241 atctcaaagc tgtactttga ttttcattga gtactagaag gaaatccttc aaattacaga
    60301 tttctttcac cgccttttcc attttgtggt ataatgaaaa atgttgacaa atagtataat
    60361 aaaaacaaag gagaacagta tgctgaaatg ggaagacttg cctgtggaaa tgaaatcaag
    60421 cgaggttgag tcttactacc atcttgtctc taaaaggaag ggttcgctga ttttcaagcg
    60481 ttgcttggac tggtttttgg ccttggtctt actggttcta acctctccca tctttctcat
    60541 cttgagcatt tggatcaagt tggatagcaa ggggccagtg atttacaagc aagagcgtgt
    60601 gacccagtac aaccgtcggt tcaagatttg gaagttccgt accatggtga cggatgcgga
    60661 taaaaaagga agtctggtga cttctgctaa cgatagccgt attaccaagg ttggaaattt
    60721 catccgacgt gtccgtttgg acgaactgcc tcagttggtc aatgtcctta aaggtgagat
    60781 gtcctttgtc ggtacacgac ctgaagtgcc acgttataca gagcagtata gccctgaaat
    60841 gatggcaacc ttgctcttgc aagcaggaat tacctctcca gccagcatca actacaagga
    60901 tgaggacacc atcatcagtc aaatgacgga gaaaggtctg tcagttgatc aggcctatgt
    60961 ggagcatgtt cttcctgaaa agatgcgcta taacctcgcc tatctccgag agtttagttt
    61021 ctttggggac atcaaaatca tgtttcaaac cgtgtttgag gtactaaaat aaagtagtca
    61081 taagaaaatg agtacagata aaaggagcaa atcaatgcca aattacaata ttccattttc
    61141 accgcctgat atcacagaag cagaaattgc tgaagtagcg gataccctgc gttctggttg
    61201 gatcacaaca ggtcctaaaa caaaagaact ggagcgccgc ttgtctcttt acacacagac
    61261 acctaagact gtttgtctca actctgcgac agccgctctg gagttgattt tacgcgtttt
    61321 ggaagtggga cctggtgatg aagtcatcgt tccagccatg acctatacag cttcatgtag
    61381 tgtcattacg cacgtgggag caacccctgt catggtggat atccaagcag atacgtttga
    61441 gatggactat gacctgcttg agcaagctat cactgagaaa actaaggtga ttatcccagt
    61501 agagctcgca gggattgttt gcgattatga ccgtttgttc caagtcgtgg agaaaaaacg
    61561 tgacttcttt actgcttcaa gcaagtggca aaaggccttt aaccgtattg tcattgtctc
    61621 tgatagtgcc cacgctttgg gatctactta taaaggacaa ccttctggtt ctatcgctga
    61681 ctttacttcc ttctcattcc atgccgttaa gaactttaca acggcagaag gtggaagtgc
    61741 gacttggaaa gccaatccag tgattgatga cgaagagatg tacaaggaat tccaaatcct
    61801 ttcccttcac gggcaaacta aggatgctct tgccaagatg caactggggt catgggaata
    61861 cgatatcgtt acaccagcct ataagtgcaa catgaccgat atcatggctt cacttggttt
    61921 ggtacaattg gaccgctatc caagtttgtt gcaacgccgt aaggacattg tggaccgcta
    61981 tgatagtggt tttgcaggtt ctcgcatcca tcctttggca cacaagactg aaactgtcga
    62041 atcttcacgc cacctctaca tcacccgtgt agaaggagca agcctagaag aacgcaacct
    62101 catcatccaa gaattggcta aagcaggaat tgcaagtaat gttcactaca aaccgcttcc
    62161 tctcttgaca gcctataaga atcttggatt tgatatgacg aactatccta aggcctatgc
    62221 cttctttaag aatgaaatta ccctccctct tcatactaaa ttaagcgatg aagaagtaga
    62281 ctatatcatt gagactttca aaacagtttc tgaaaaagtg ctaactttat caaaaaaatg
    62341 acaaactaca gtcaagcgaa agtgatcctg tccctaaaaa gtctaattga gtgtaaaaac
    62401 tgttgttttc aattgataat agtttacacc tgtagttgag gcctctttct cctcagagag
    62461 agaattttta taggattttc ctttcttgtg agagtcccgt ggtttgaaat aagatgtgag
    62521 caatttggtg tagcatttag aatccttact agacatcatt tagaaaatct agtgtcttgt
    62581 tctagttttc aattcaccct attttttgaa agacgtgagt ttccatgagt gagattgtgg
    62641 aaactcgcgt ctttttttgt tttcagaata ttgttcaaag ttttgtgcct gtctttcatg
    62701 ttctagtcat tcttttgcat gatagaattt atagcatatt gatcttataa taatacaaat
    62761 attctatatg tttagtgatg cttgctatac atcattagat ctcccgcgag acaatctata
    62821 aaacacttgt ctacgattac ctatatgccc tattccagta ttttagaagc actgcatcta
    62881 tttttatcga ggttaaatct agcttttata gaaggtctat ttaagaaata tattgtagtg
    62941 ttttagtttc aatccgccat atgagcgata ttcatgtaaa tatccctggc gaatgcttgt
    63001 atgacaaggt atttgttctt tcatttataa tttacaacat atcaacaaat ttaaatatag
    63061 taaatgggat attttatatt caagctaaga aagatagcat cacttttgaa tggaaggcta
    63121 aagagcaaac taggaagttg gccatagata gctcaaaacc ctgctttgag gttgtagata
    63181 tagtaaaatg aaataagaat aggacaaatc gatcgggaca gtcaaatcga tttctaacaa
    63241 tgttttagaa gtagaggtgt actattatag tttccgtcta ctatagaact gaccaagtca
    63301 gtaacctaga cttagggcaa ggcggcactg acctagtttg aagagatttc cgaagagtat
    63361 aaattttaat attttcttgt gttattcctt gacaattcaa tttggaaaat atatgataaa
    63421 gataatgaca gcggtgtcat tctatctatt ttaagaaaag taataatcaa ttgttaaaaa
    63481 tagtaaaaaa attggaggtt ctgatgaaat attttgttcc taatgaggta ttcagtattc
    63541 gtaaattaaa ggtagggact tgctcggtac tattggcaat ttcaattttg ggaagccaag
    63601 gtattttatc ggatgaagtt gttactagtt cttcaccgat ggctacaaaa gagtcttcta
    63661 atgcaattac taatgattta gataattcac caactgttaa tcagaatcgt tctgctgaaa
    63721 tgattgcctc taattcaacc actaatggtt tagataattc gttaagtgtt aatagtatca
    63781 gctctaatgg tactattcgt tccaattcac aattagacaa cagaacagtt gaatctacag
    63841 taacatctac taatgaaaat aagagttata aggaagatgt tataagtgac agaattatca
    63901 aaaaagaatt tgaagatact gctttaagtg taaaagatta tggtgcggta ggtgatggga
    63961 ttcatgatga tcgacaagca attcaagatg caatagatgc tgcagctcaa gggctaggtg
    64021 gaggaaatgt atattttcct gaaggaactt atttagtaaa agaaattgtt tttttaaaaa
    64081 gtcatacaca cttagaattg aatgagaaag ctacaattct aaatggtata aatattaaga
    64141 atcacccttc cattgttttt atgacaggtt tatttacgga tgatggtgcg caagtagaat
    64201 ggggcccaac agaagatatt agttattctg gtggtacgat tgatatgaac ggtgctttga
    64261 atgaagaagg aactaaagca aaaaatctac cacttataaa ttcttcaggt gcatttgcta
    64321 ttgggaattc aaataacgta actataaaaa atgtaacatt caaggatagt tatcaagggc
    64381 atgctattca aattgcaggt tcgaaaaatg tattagttga taattctcgt tttcttgggc
    64441 aagccttacc caaaacgatg aaggatgggc aaatcataag taaggagagc attcagattg
    64501 aaccattaac tagaaaaggt tttccttatg ccttgaatga tgatgggaaa aaatctgaaa
    64561 atgtgactat tcaaaattcc tattttggca aaagtgataa atctggggaa ttagtaacag
    64621 caattggcac acactatcaa acattgtcga cacagaaccc ctctaatatt aaaattttaa
    64681 ataatcattt tgataacatg atgtattcag gtgtacgttt tacaggattc actgatgtat
    64741 taatcaaagg aaatcgcttt gataagaaag ttaaaggaga gagtgtacat tatcgagaaa
    64801 gcggagcagc tttagtaaat gcttatagct ataaaaacac taaagaccta ttagatttaa
    64861 ataaacaggt ggttatcgcc gaaaatatat ttaatattgc cgatcctaaa acaaaagcga
    64921 tacgagttgc aaaagatagt gcagaatatt taggaaaagt atcagatatt actgtaacaa
    64981 aaaatgtagt taataataat tctaaggaaa cagaacaacc aaatattgaa ttattacgag
    65041 ttagtgataa tttagtagtc tcagagaata gtatattcgg tggtaaagaa ggaattgtta
    65101 ttgaggattc aaagggtaaa ataaccgttt taaataacca attttataat ttatccggta
    65161 agtatatatc attcatcaaa tctaatgcaa atgggaaaga acctgttata cgtgatagcg
    65221 atggtaattt caatattgta acggagaatg ggctttacaa aattgtaaca aataatttaa
    65281 gtgataaaaa cgaaaaagaa aaaaacaaag aggaaaaaca atctaattca aataatgtaa
    65341 ttgatagtaa ccagaagaac ggagagttta actcaagtaa agataataga caaatgaatg
    65401 acaagatcaa caataaacaa gataataaga cagaagaagt aaactataaa atagttggag
    65461 atggcagaga aactgaaaat catattaata aatctaaaga aatagtagat gtaaaacaaa
    65521 aattaccaaa gactggttcg aacaagatta tggaactatt cttaacagtg acaggaattg
    65581 gtttactttt gacactaaaa gggttgaagt attatggtaa agataaataa aatttgttcg
    65641 atacaaggaa gttccgtaga aaatgaggat attgtaggtt cacaaaatca gtatttttgg
    65701 attattggtg gagctacaga tttatataat tctaaagagg agataggtta ttcagtctca
    65761 gaagttgtac atattttatc agaaagtttg tcggttaatt gtaaagaatc aaaaactctt
    65821 aaacaaatat ttgaaactgc tttactcgag gttaaagatg aaatcggttt aaactcatat
    65881 gaattaacag agtatagtaa aatgaaataa taataggaca aatcaatcag gacagtcaaa
    65941 tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa tatactatat
    66001 tatcgcttac caatatttgc ttttatattt gctaaacttt cagaaaaaaa gttggagtat
    66061 atgatgctag gtgactgcgt catgttagta aacgaaatgg aaataactga tcatagagta
    66121 gataacttat ttgaaaaagg gaaaaatgag ataaaagatt caattggtac aaatagtgtt
    66181 ttaaataaaa aaattatttt acaaaaaatc agaaaattat ctaatcaacc gagtgggtac
    66241 tggataggtt cgttggatga gagattttta gaccatgcta ttattaatca aatagatgtt
    66301 actagtgaac aaattgtttt aatgagcgat ggcttttatg aattctatca aaataatcaa
    66361 aataaaactt ttgaagagtt aattaagatg agatttaatt cttctgctat tgatccaatc
    66421 tatggaaaga aggatgatgc aagtattcta gtcattgatg tttgatatat tgtttaaaat
    66481 attaattgtt actattgaac tttgttaaga agaggtacct aaatgttaag gttatattta
    66541 gaaaatgaaa ttatagaatt atcaaataat ttagagacca tttgggtatc tgtgcttgat
    66601 aaatatgaga agttatttga atatttatca aatgaagaac gagtagaatt gattaaagaa
    66661 gatttaatca taaatgagtc agttctaaat attgataaaa aaggata
//
LOCUS       DAVLBN010000004        56923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLBN010000004 DAVLBN010000000
VERSION     DAVLBN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.004"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(99..632)
                     /gene="queF"
                     /locus_tag="VXC24_000212"
     CDS             complement(99..632)
                     /gene="queF"
                     /locus_tag="VXC24_000212"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0492393.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VXC24_000213"
     CDS             complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VXC24_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0492394.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(1270..1491)
                     /locus_tag="VXC24_000214"
     CDS             complement(1270..1491)
                     /locus_tag="VXC24_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0492395.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(1590..1970)
                     /locus_tag="VXC24_000215"
     CDS             complement(1590..1970)
                     /locus_tag="VXC24_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0492396.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(2115..3068)
                     /locus_tag="VXC24_000216"
     CDS             complement(2115..3068)
                     /locus_tag="VXC24_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0492397.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VXC24_000217"
                     /pseudo
     CDS             complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VXC24_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            4483..5043
                     /locus_tag="VXC24_000218"
     CDS             4483..5043
                     /locus_tag="VXC24_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0492398.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            5100..6008
                     /locus_tag="VXC24_000219"
     CDS             5100..6008
                     /locus_tag="VXC24_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0492399.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5960..6550
                     /locus_tag="VXC24_000220"
     CDS             5960..6550
                     /locus_tag="VXC24_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0492400.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            6553..7659
                     /gene="yqeH"
                     /locus_tag="VXC24_000221"
     CDS             6553..7659
                     /gene="yqeH"
                     /locus_tag="VXC24_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0492401.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7873..8184
                     /gene="yhbY"
                     /locus_tag="VXC24_000222"
     CDS             7873..8184
                     /gene="yhbY"
                     /locus_tag="VXC24_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0492402.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            8236..8865
                     /locus_tag="VXC24_000223"
     CDS             8236..8865
                     /locus_tag="VXC24_000223"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0492403.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8865..9458
                     /gene="yqeK"
                     /locus_tag="VXC24_000224"
     CDS             8865..9458
                     /gene="yqeK"
                     /locus_tag="VXC24_000224"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0492404.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            9459..9959
                     /locus_tag="VXC24_000225"
     CDS             9459..9959
                     /locus_tag="VXC24_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0492405.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            9972..10325
                     /gene="rsfS"
                     /locus_tag="VXC24_000226"
     CDS             9972..10325
                     /gene="rsfS"
                     /locus_tag="VXC24_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0492406.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            10428..11174
                     /locus_tag="VXC24_000227"
     CDS             10428..11174
                     /locus_tag="VXC24_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0492407.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            11184..12281
                     /locus_tag="VXC24_000228"
     CDS             11184..12281
                     /locus_tag="VXC24_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0492408.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            12519..12773
                     /locus_tag="VXC24_000229"
     CDS             12519..12773
                     /locus_tag="VXC24_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0492409.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12777..13031
                     /locus_tag="VXC24_000230"
     CDS             12777..13031
                     /locus_tag="VXC24_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV0492410.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13222..14835
                     /locus_tag="VXC24_000231"
     CDS             13222..14835
                     /locus_tag="VXC24_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0492411.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14965..15591
                     /gene="gmk"
                     /locus_tag="VXC24_000232"
     CDS             14965..15591
                     /gene="gmk"
                     /locus_tag="VXC24_000232"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0492412.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15616..15930
                     /locus_tag="VXC24_000233"
     CDS             15616..15930
                     /locus_tag="VXC24_000233"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0492413.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            15996..18392
                     /locus_tag="VXC24_000234"
     CDS             15996..18392
                     /locus_tag="VXC24_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0492414.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18405..19340
                     /locus_tag="VXC24_000235"
     CDS             18405..19340
                     /locus_tag="VXC24_000235"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0492415.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19333..20646
                     /gene="rsmB"
                     /locus_tag="VXC24_000236"
     CDS             19333..20646
                     /gene="rsmB"
                     /locus_tag="VXC24_000236"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0492416.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20661..21401
                     /locus_tag="VXC24_000237"
     CDS             20661..21401
                     /locus_tag="VXC24_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0492417.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            21398..23377
                     /gene="pknB"
                     /locus_tag="VXC24_000238"
     CDS             21398..23377
                     /gene="pknB"
                     /locus_tag="VXC24_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0492418.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23492..24250
                     /locus_tag="VXC24_000239"
     CDS             23492..24250
                     /locus_tag="VXC24_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0492419.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24252..24701
                     /locus_tag="VXC24_000240"
     CDS             24252..24701
                     /locus_tag="VXC24_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0492420.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24763..25389
                     /locus_tag="VXC24_000241"
                     /pseudo
     CDS             24763..25389
                     /locus_tag="VXC24_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25457..25705
                     /locus_tag="VXC24_000242"
     CDS             25457..25705
                     /locus_tag="VXC24_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492421.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25836..27008
                     /locus_tag="VXC24_000243"
     CDS             25836..27008
                     /locus_tag="VXC24_000243"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0492422.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27008..28282
                     /locus_tag="VXC24_000244"
     CDS             27008..28282
                     /locus_tag="VXC24_000244"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0492423.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(28318..29283)
                     /locus_tag="VXC24_000245"
     CDS             complement(28318..29283)
                     /locus_tag="VXC24_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0492424.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(29264..30718)
                     /locus_tag="VXC24_000246"
     CDS             complement(29264..30718)
                     /locus_tag="VXC24_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0492425.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            30771..30968
                     /locus_tag="VXC24_000247"
     CDS             30771..30968
                     /locus_tag="VXC24_000247"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492426.1"
                     /translation="MQAFYVKKEEKLSKDYHKINTGNQSNFYENVKDNEIKDFLTKVS
                     NLFFKEFLMKQSKTINLKLAH"
     gene            31094..32977
                     /locus_tag="VXC24_000248"
     CDS             31094..32977
                     /locus_tag="VXC24_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0492427.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            33126..34013
                     /locus_tag="VXC24_000249"
     CDS             33126..34013
                     /locus_tag="VXC24_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0492428.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(34056..34673)
                     /locus_tag="VXC24_000250"
     CDS             complement(34056..34673)
                     /locus_tag="VXC24_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0492429.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(35088..35276)
                     /locus_tag="VXC24_000251"
                     /pseudo
     CDS             complement(35088..35276)
                     /locus_tag="VXC24_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(35786..35866)
                     /locus_tag="VXC24_000252"
                     /pseudo
     CDS             complement(35786..35866)
                     /locus_tag="VXC24_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            35982..36875
                     /locus_tag="VXC24_000253"
     CDS             35982..36875
                     /locus_tag="VXC24_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492430.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            36872..38071
                     /locus_tag="VXC24_000254"
     CDS             36872..38071
                     /locus_tag="VXC24_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492431.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(38424..39191)
                     /locus_tag="VXC24_000255"
     CDS             complement(38424..39191)
                     /locus_tag="VXC24_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492432.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(39208..39903)
                     /locus_tag="VXC24_000256"
     CDS             complement(39208..39903)
                     /locus_tag="VXC24_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492433.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(39908..40273)
                     /locus_tag="VXC24_000257"
     CDS             complement(39908..40273)
                     /locus_tag="VXC24_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0492434.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            40413..40886
                     /gene="nrdR"
                     /locus_tag="VXC24_000258"
     CDS             40413..40886
                     /gene="nrdR"
                     /locus_tag="VXC24_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0492435.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            40887..42056
                     /locus_tag="VXC24_000259"
     CDS             40887..42056
                     /locus_tag="VXC24_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0492436.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            42057..42953
                     /gene="dnaI"
                     /locus_tag="VXC24_000260"
     CDS             42057..42953
                     /gene="dnaI"
                     /locus_tag="VXC24_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0492437.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            42950..43663
                     /locus_tag="VXC24_000261"
     CDS             42950..43663
                     /locus_tag="VXC24_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0492438.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            43677..44987
                     /gene="der"
                     /locus_tag="VXC24_000262"
     CDS             43677..44987
                     /gene="der"
                     /locus_tag="VXC24_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0492439.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            45078..45413
                     /locus_tag="VXC24_000263"
     CDS             45078..45413
                     /locus_tag="VXC24_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492440.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            45553..45888
                     /locus_tag="VXC24_000264"
     CDS             45553..45888
                     /locus_tag="VXC24_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492441.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            46073..46864
                     /locus_tag="VXC24_000265"
     CDS             46073..46864
                     /locus_tag="VXC24_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492442.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            46857..47498
                     /locus_tag="VXC24_000266"
     CDS             46857..47498
                     /locus_tag="VXC24_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492443.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            47502..48152
                     /locus_tag="VXC24_000267"
     CDS             47502..48152
                     /locus_tag="VXC24_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0492444.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            48163..48450
                     /locus_tag="VXC24_000268"
     CDS             48163..48450
                     /locus_tag="VXC24_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492445.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            48596..51109
                     /gene="secA"
                     /locus_tag="VXC24_000269"
     CDS             48596..51109
                     /gene="secA"
                     /locus_tag="VXC24_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0492446.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            51190..52221
                     /locus_tag="VXC24_000270"
     CDS             51190..52221
                     /locus_tag="VXC24_000270"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0492447.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            52223..53254
                     /locus_tag="VXC24_000271"
     CDS             52223..53254
                     /locus_tag="VXC24_000271"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0492448.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            53293..53661
                     /locus_tag="VXC24_000272"
     CDS             53293..53661
                     /locus_tag="VXC24_000272"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0492449.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            53651..54754
                     /locus_tag="VXC24_000273"
     CDS             53651..54754
                     /locus_tag="VXC24_000273"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0492450.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            54773..56788
                     /gene="recG"
                     /locus_tag="VXC24_000274"
     CDS             54773..56788
                     /gene="recG"
                     /locus_tag="VXC24_000274"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0492451.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
BASE COUNT        16827 a        10960 c        12989 g        16147 t
ORIGIN      
        1 agctgacttc gtcagtttta tctacaacct caaacactgc tttgagtaac ctgcggctaa
       61 cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc aattttctct
      121 ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc cctcatactt agttccttgc
      181 ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa ttttccccag
      241 acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt gttgatacag
      301 ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag ggattttgac
      361 tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca
      421 gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg ttccttagcg
      481 atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct
      541 tcgactgttt catagtgttg catggtccag aaaaggcagg tttttgaatc ttgaccacca
      601 ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc
      661 agagcacgta aaaagctccc attagggagc taaaaaatac caaatcgagg ttttttttag
      721 cgatggcata tcccaaatat cgtaatattc tatttatata gtaaaatgaa ataagaacag
      781 gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agagatgtac
      841 tattctagtt tcaatctact atagtctagc atatcttttg aaaaatggca aagggcaaga
      901 aaaaagagac caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg
      961 gccttgattt gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt
     1021 ttgaagagaa gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca
     1081 tcaacgtcca ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc
     1141 aagattggac cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc
     1201 aaaccgtctt ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt
     1261 ctcctttttt tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc
     1321 ataagtccca tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta
     1381 gtctgcgacg ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa
     1441 agtcacagtt ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac
     1501 tcctttgttt aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga
     1561 ttgcgcacgc aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag
     1621 ctttcttcga cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag
     1681 ataaaactag agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta
     1741 gcttccaagc gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc
     1801 aggtcaatct ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac
     1861 tctttcaagg tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca
     1921 atttctttct gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct
     1981 ttctttttag agtcataatt atagaagaaa gtccattaac gggcagtctt tgcgtcataa
     2041 gatgattgcg catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt
     2101 agtggttttc ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag
     2161 gttttggctt cacgtaggag ttgaagaaga gtggcgcggg tttcaaactc ttctcttgtc
     2221 ttgggcagac tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca
     2281 gaagcaggat tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc
     2341 aggctttcac tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata
     2401 cgactttgtc gttgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg
     2461 tggtcagagt gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct
     2521 gctaccagct gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg
     2581 aggatatctt ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt
     2641 gaaggcatat agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat
     2701 tcgttgacta ggaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaacc
     2761 gtgcttggtg tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc
     2821 agatagaggc cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacgccgata
     2881 gccagagcta gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc
     2941 gtatcagata ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga
     3001 aaataagcaa gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta
     3061 atagacataa gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag
     3121 gcttgccttg atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag
     3181 gacatctgta gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa
     3241 accaacccca acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac
     3301 tgggataaga aggagggaac ctccggcaat acctgaagca tcacaggctg agatagctgc
     3361 taccacactg aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgt
     3421 aacaagggtc aaaacgttaa tggtaatcgc tactccagcc atattgatag tagaaccgag
     3481 tgggatagaa acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt
     3541 gacaggaatg ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag
     3601 gcagttccaa actagagggt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt
     3661 gaccacaggg gcaacaaaaa gcatagtcgt tactaataga accaataaaa taccgtagtt
     3721 ggcaaggctt ccgactccct tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa
     3781 tggagccaga ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag
     3841 caattcttta ctatttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga
     3901 taagattcta atatagttag cagtaagcag ggcgttgact gggttgtcaa ccagtttgag
     3961 caagaggttg ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact
     4021 atttagggta atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc
     4081 gaaagtccct atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc
     4141 ttttgatgtt ggaaagggca ttggcaacga gggcaaagac taggatagga gcaacagctt
     4201 ttagacctcc aacgaataaa tccccgagta gcccaatccc tgagagatta ggaagggtca
     4261 gtcctaggat tccccacaaa gcataccaat caagatacgc ttgacaaggc ttgccttatt
     4321 ccaagcatga atgattcttt tcataataat ctcctttttg tgtagtgatt atgattatag
     4381 tataaatgat agacaaaatc aagaattttc tgtctatttt ttgaatattt atggagaatg
     4441 agactgatga aaatatggta taatgaaata aaggagtttt atatgcaaaa atttattcag
     4501 gcttatattg aaaagctaga tgtgacaacc attatcgaga atattctaac caaggtcatt
     4561 tctcttttac tgcttttgat tgtattttat attgctaaaa aaatgcttca taccatggtg
     4621 cagagaattg tcaaaccttc tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc
     4681 atctcacgtt tactagaaaa tgtgtttaat tatacgctat atttcttttt actctactgc
     4741 attttgtcga ttttaggttt gccagtttct agtttgctgg ctggagctgg tattgctggg
     4801 gtagcgattg gtatgggagc ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc
     4861 ctctttgaac gtcaactgga tgtgggagat gaggtcgttc tgacaaatgg accgattact
     4921 gtatcgggta aggttgtcag tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa
     4981 gcccttcact ttgtccctaa ccgaaatatc acagttgtta gcaatttctc acgcacagac
     5041 tagacctgtt attttaagta atttgtggta caatagaggg agtttaataa ggagaaaaga
     5101 tggttttaga aaagcagttg ggcaatggtt gtacctggat agacctagac ctaggaaagt
     5161 tgaataaact agaagacctt tctgaaattt acggtttgga caaggaaacc attgaatacg
     5221 cactggatag aaacgagcgc gcccacatgg attaccaccg tgaaagtggg acggttacct
     5281 ttatctataa tgtcctagac gtaaaaaagg acaaggccta ctatgagact tttcccatga
     5341 cctttattgt cgagcatcgt cgcctgatta ccattagtaa taccaagaac gcctatgtca
     5401 ttgaacagat gactcgttat ctggagagcc atgacacgct ttcgatttat aagtttctct
     5461 ttgccagtct ggaaattatc agcaatgcct actatcctgt cattgagcag atggacaaga
     5521 gtagggatga ggtcaatgac ctcttgcgcc agcgaactac caagaaaaac ctctttgccc
     5581 tgtctgattt ggagactggt atggtttatc tgacggcagc tgccaaacaa aatcggattt
     5641 tgttagagca tattcaaggt catgccttgt atcgtagttt tgatgagatt gagagagaac
     5701 agtttgatga tgccatgatt gaggctcatc agctggtatc catgacagac ctaatctctc
     5761 agattttaca gcagctttca gcctcttaca acaatattct aaacaataat ctgaatgaca
     5821 atttgacaac cttgactatc atttcagtct tgctagctgt tttggcagtc gtgacaggct
     5881 ttttcggaat gaatgttccc ttacctttaa cagatgagcc ccatgcttgg ctctatatca
     5941 gtttggctag tgcaggtttg tggattgttt tatccttgtt actaaggaaa attgcgaaaa
     6001 aaagttaaga aaaggagcca gaatggcgat tgaaaattat ataccagatt ttgctgtgga
     6061 agcagtctat gatctgacag tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt
     6121 cgatttggat aataccctca ttgcttggaa caaccctgat ggaacgccag agatgaagca
     6181 atggctacat gaccttcggg acgcgggtat tggcattatc gtagtgtcaa ataacaccaa
     6241 aaaacgcgtt caacgagcag ttgagaaatt tgggattgat tacgtttact gggccttgaa
     6301 gcccttcaca tttggtattg accgtgctat gaaggaattc cactatgaca aaaaggaagt
     6361 ggtcatggtt ggcgaccagc tcatgacaga tatacgagca gcccaccgtg cagggattcg
     6421 gtcaatttta gtcaaaccct tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac
     6481 tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac ggaccgatta catataaaaa
     6541 aggaatttaa ctatggaaga aattctctgt attggttgtg gagcaaccat tcagacgaca
     6601 gataaagctg gtcttggttt taccccccag tcggcacttg aaaaaggttt ggagactggc
     6661 gaagtctatt gccaacgctg tttccgtctc cgccactaca atgaaatcac agatgtccag
     6721 ttgacgaacg atgatttcct caagctcttg cacgaggtgg gagacagtga tgccttagtg
     6781 gtcaatgtca ttgatatctt tgattttaat ggatctgtca tcccaggttt accacgtttc
     6841 gtctcgggca atgatgtcct cttggtagga aataaaaaag atatccttcc taagtcagtt
     6901 aagtctggta agattagcca gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca
     6961 gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca ttaaggaagt cattgacaag
     7021 attgaacact accgtaaggg ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa
     7081 tcaactctaa tcaatgctat tatccaagaa atcacgggtg atcagaatgt catcactact
     7141 tcacgcttcc caggtacaac cttggacaaa atagagattc cgcttgacga cggatcttat
     7201 atttacgata cgccgggaat tatccaccgc caccagatgg ctcactactt gacggccaaa
     7261 aacctcaagt atgtcagtcc taaaaaggaa atcaagccta agacctatca gcttaatcct
     7321 gagcaaaccc tatttttagg tggtttggga cgctttgact ttatagcagg agaaaagcaa
     7381 ggatttactg ctttctttga taatgaactc aaactccatc gtagcaagct tgaaggagct
     7441 agtgctttct acgataagca cctgggaact cttctgacac caccaaatag caaggaaaaa
     7501 gaagatttcc caaggctagt ccagcatgtc tttaccatta aagataagac agacctagtc
     7561 atctcaggcc taggctggat tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca
     7621 gaaggcgtcg ccgtcgtcac acgaaaagca attatttaaa acaaaatcgc tgagcgaaca
     7681 aagtgagctc atatagcgat agttattgcc gtggtgtgat tgccaatctg tagattggca
     7741 aggggcacaa ttgagaccaa ggctcaattg tgaggtcagg aaatccattt ttcaaagatg
     7801 aaatctttgg aaaattagtt ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca
     7861 aggaagaaaa ttatgtcatt aacatcaaaa caacgtgcct tcctcaacag ccaggcacac
     7921 accctcaaac ctatcatcca aatcgggaaa aatggactca acgaccaaat caaaaccagc
     7981 gtccgtcaag ctcttgatgc gcgtgaatta atcaaggtta ctctcttaca aaacacagat
     8041 gaaaacatcc acgaagtagc tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa
     8101 aaaataggac gcatcttgat tttgtttaaa caatctagca agaaagaaaa tcgcaagatt
     8161 tctaagaaag tcaaagaaat ctaagaccga aactccaaat aactgttttt atagagaaat
     8221 aaaggggact agcctatgac aatcgaacta ttgactccct ttaccaaggt agagttggag
     8281 ccagaaatca aggagaaaaa acgcaaacaa gttgggattt taggggggaa ttttaaccct
     8341 gttcacaatg cccatctcat tgttgcggat caagtacggc aacagttggg actggatcaa
     8401 gttcttctca tgcctgaata ccaacctcct cacgttgata aaaaggaaac catccctgaa
     8461 caccatcgtc tcaagatgct tgagttggca attgagggaa ttgacggcct agtcattgaa
     8521 accattgagt tggagcgcaa gggtatttcc tacacctacg acaccatgaa gattttgaca
     8581 gagaagaatc cagatacgga ttattacttt atcatcggtg ccgacatggt tgagtatctg
     8641 cctaagtggt accgaattga tgaactggtt gacatggttc agtttgtggg ggttcagcgt
     8701 ccacgctaca aggtagggac ttcctatcca gttatctggg tggacgtacc gctcatggat
     8761 atctcgtcca gcatggtgcg ggacttcctt gcccaaggtc ggaaacccaa ctttctccta
     8821 cctcagccag tgctagacta catcgagaag gaggggctct actgatgtcc tatcaagact
     8881 atatcaactg ctcccgtgag gccttgttgg aaaaaatggc agagcttcta cctgagaaac
     8941 gtctaaccca ttgtctaggt gtggagcgtg ccgctatgga attagctcag cgctttggtg
     9001 tagatgttgg gaaagcaagt ctagcaggtc ttcttcatga ctatgctaaa aagttgtcaa
     9061 atcaggaatt tctagccttg attgaccgtt accagctaga ccctgacctc aaaaactggg
     9121 gcaataatgt ctggcatggt atggtcggaa tttacaaaat tcaggaagat ttggatttgc
     9181 atgattctga aattctgcga gccattgaaa ttcatacagt cggagctggt caaatgacag
     9241 acctagataa ggtcatctac gtcgcagact atatcgagca caatcgagcc tttcctggag
     9301 tagatgtggc gcgtgagatt gcaagtctat cgctcaataa ggcggtggcc tacgaaacag
     9361 ctcgtaccgt ggagtatcta gctcatcagg gattccccat ctatccccaa acccttgaaa
     9421 cctataacgc ctttgtgcac tatttgaaag aggactaaat gaagacggct tttataatca
     9481 ttgatgttca gaatgtttta gtagaaactg ggttccagac aaaaagtcta ttggaaaaaa
     9541 tttcttattt acaaaaccag gctagaagca agaatattga aattatctat gttcaacata
     9601 ttgagaattc tgaagctcaa acatcagaag attggcagtt atctgcgctt ttaaatcgaa
     9661 aacctgctga aaaggtcttt cagaagaagt ataacagtat tttcaaagaa actggcttaa
     9721 aagaatactt ggataaacag gggattgaaa aattagtttt atgtggtatg cagacagaat
     9781 attgtgtgga tacctctgtc aaggttgcct ttgaatatgg ctatcagctt attgttccag
     9841 aaggtgctgt cacaaccttt gatggggatg acattccagc agaaacgatt aatgaatttt
     9901 atgaggacat ttgggaggag cactttgcag atgtcctaga ttacaaacat attttctaaa
     9961 aagaggatta aatgaacgaa aaagaattac tagaactagt cgtgaaagcg gctgatgaga
    10021 aacgtgcgga ggatatcctc gcacttgatg tacaagattt gactagtgtg acggactact
    10081 ttgtcatcac tagctcaatg aatagccgtc agttggacgc tatcgcagct aatatccgtg
    10141 aaaaagtagc tcaagcgggc tttaaaggta gccatgtcga aggcgatgca gctggaggct
    10201 gggtcttact ggacctcggt gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc
    10261 attataatct agagaagcta tggcatgagg cgaattcagt agatatttca gaagctcttg
    10321 cttagaagat gaactcagtt gtagtcaact gggtttcttt gcttatttta gaaaaattga
    10381 tagaaaggta aagggctagt ggtgtttacc atggagctct tagtatcatg attatggcga
    10441 cttatgaaac ctttgcggcg gtctatgatg cggtcatgga cgatagttta tacgacaaat
    10501 ggacgaattt ttctctgcgt catttgccta agaccaagga gaaaaagaaa ctcttggaac
    10561 tggcttgtgg gacaggaatt caatcagtgc gcttctctca ggctggtttt gatgtgactg
    10621 gacttgactt gagtgcggat atgttgaaga ttgcggagaa gagagcaact tcagccaagc
    10681 aaaagattgc ttttatagaa ggtaacatgc tgaatttgtc caaggcaggg aaatacgatt
    10741 ttgtcacgtg ttattcggac tctatctgct atatgcagga tgaggtggaa gtaggggacg
    10801 tctttaagga cgtgtacaat gcgctgaatg aagagggagt tttcatcttt gacgtgcact
    10861 cgacctacca gacagatgaa gtattccctg gctattccta ccatgaaaat gcggaagatt
    10921 ttgccatgct ttgggataca tatgaggacg aagctcctca ctccatcgtg catgagctga
    10981 ctttctttat caaggaggct gacggttcct ttagtcgcca cgatgaagta catgaggaga
    11041 ggacctatga gatcttgacc tatgatatct tactggaaca ggctggattc aagtccttca
    11101 aactctatgc agactttgag gataaggaac caacagaaac tagcacccgt tggttttttg
    11161 tggcgcagaa gtaggagatt agcatgacca tcacaggtat tatcgcggag ttcaatcctt
    11221 ttcataatgg ccataaatac ctgctggatc aggcagaggg actgaaaatt gttgccatgt
    11281 cagggaattt catgcagcgt ggagagcctg ctattgtgga taagtggaca agggcccaga
    11341 tggcgctgga aaatggcgca gacttggtag tggaattgcc ctttttagtc agtgttcagg
    11401 cagctgattt ctttggtcaa ggagctgtga atatcttgga tcgcttgggc attgatagtc
    11461 tagtttttgg gacagaggaa gttcgagatt atcagaaaat cgctgactta tacacagaga
    11521 aaggtgctga gatggagaaa tttgtggaaa atctgcctga ttccctttcc tatccccaga
    11581 aaacccaagc tatgtggaag gaatttgctg gtcttgattt ttcaggtaat acccccaatc
    11641 atgttcttgc tctggcctat gccaaggcgg ttgcaggacg aaatatcaag ctgcatccga
    11701 ttcagcgtca gggggcaggt taccattctg tgaataaaga tgtggacttt gcctcggcga
    11761 cagccctccg tcaacatcag aaggaccaag atttcttaga acgctttatg ccttctgttg
    11821 ccctatttga gcaggccagt aaggtgatct gggaagacta ttttcccttg ctccgctatc
    11881 aaatcttgtc aaatcccgac ctaaccacca tctatcaggt caatcaagaa atggctgtgc
    11941 gcattaaaga agctattaaa acagcccggt ctgtggaaga attggtcgag ttagtgacta
    12001 ccaaacgtta caccaaggcg cgtgtcagac gcctattgac ctatattttg atgcaggcta
    12061 gagaaaatgt cttgccagaa gtcattcatg tccttggatt tactgaaaaa ggtaggcaac
    12121 atctcaagtc tttgaaaggt caggtcagtc tagtcagccg aattggcaaa gaaccttggg
    12181 atgctatgac ccaaaaagca gaccagattt accaactagg aaatccaagt atagcagacc
    12241 agaattttgg aagagtgccg attagaatag aaacaaacta agtctaccga aaggtaggct
    12301 ttttgagatt ttttacgaat aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg
    12361 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    12421 gagtataaat agatagaaaa gaaaatcttg tacaagttcc tgacaatttc tttcttttcg
    12481 tgtataatag tggaaaagag ctaaaacgag gtatggttat ggaagcagtc ctttactcaa
    12541 cattccgaaa tcatttaaag gactacatga agaaggtaaa tgatgaattt gagcctttga
    12601 cggtggtcaa taaaaatcca gatgaggaca ttgtagtcct ttcaaagagt gagtgggata
    12661 gtatccaaga aaccctgaga attgctcaaa ataaggaact ttctgataag gttttgcgag
    12721 gaatggctca agttcgtgct ggaagtactc aggtccatgt tattgaggag taagaaatgc
    12781 tgctcaagtt tacagaagat gcctgggcag attattgcta ctggcaaaat caggataaga
    12841 aaacgttaaa aagaatcaat aaactaatca aggatattca acgtgatccc tttacaggaa
    12901 taggtaaacc agaaccactc aaatatgatt accaaggagc ctggtcacgg cgtattgatg
    12961 cagaaaatcg cttgatttat atgatggatg gagatagcgt ggctttcttg tcctttaaag
    13021 atcattacta agtctattga aaggtaggct ttttctcaag tctctactaa actactattt
    13081 ctaaacaaca agtttatttt tgcaaatgtg ttccaaattc cccaaaacat attctatttt
    13141 aggtttgtga aaatcacttt tttatggtag aatgtaaaag aatgtatgtc attcggaata
    13201 acaataaaat gaggtaaaaa catggaaatc atgtcgcttg cgattgctgt ttttgccgtc
    13261 atcattggtt tagtcattgg atatgtcagc atctcagcta agatgaaatc atctcaggaa
    13321 gctgcagagt tgatgctttt aaatgctgaa caagaagcaa ctaatttacg tggacaagct
    13381 gagcgtgaag cggatttact tgttaatgaa gccaaacgtg aaagcaagtc tcttaaaaaa
    13441 gaagcactat tggaggccaa agaagaagcc agaaaatacc gtgaagaagt ggacgctgaa
    13501 ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc gtttgacaga gagagctact
    13561 agccttgacc gtaaggacga caatttgacg agtaaagaac aaacacttga acaaaaagaa
    13621 caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg aagagcaatt agaggaagtc
    13681 gaaagacaaa aagaagcaga actagagcgt attggtgctc tgtctcaggc agaagcacga
    13741 gatattatct tggctcagac agaggaaaac ttgaccaggg agattgccag tcgcattcgc
    13801 gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg ccaaggacat cttggttcaa
    13861 gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa caaactcaac ggttcatctg
    13921 ccagacgata ctatgaaggg acgcattatt ggtcgtgaag gtcgtaacat tcgtaccttt
    13981 gaaagtttga caggggtcga tgtgattatc gacgatacac cagaagtggt gaccttgtca
    14041 ggatttgatc cgattcgtcg tgagattgcc cgtatgacta tggaaatgtt gctcaaagat
    14101 ggtcgtatac atccagctcg tatcgaagag ttggttgaga aaaaccgtca agagattgac
    14161 aataagattc gtgaatacgg tgaggctgct gcctatgaaa ttggtgcgcc aaaccttcat
    14221 ccagacttga tgaagattat gggacgtttg cagttccgta cttcatatgg acaaaatgtt
    14281 ttgcgccatt cgattgaggt tgctaagttg gctggtatca tggcgagcga acttggtgaa
    14341 aatgcggctc ttgcccgtcg tgctggattc cttcacgata tcgggaaagc cattgaccat
    14401 gaggttgaag gtagccacgt tgaaatcggt atggaattgg cccgtaagta caaggaaccc
    14461 ccagttgtgg tgaatacgat tgctagtcac cacggagatg ttgaagctga gagcgtgata
    14521 gcagttatcg tcgctgcagc agatgccttg agcgcagccc gtccaggtgc tcgtagtgag
    14581 tctcttgaaa gctacatcaa gcgtctccat gatttggaag aaattgctaa cggctttgaa
    14641 ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa ttcgtatcat ggtcaatcca
    14701 ggaaaaatca aggacgacaa agtcacaatc ttggctcaca aagttcgtaa gaaaattgaa
    14761 aacaatctcg attatccagg aaatatcaag gtaaccgtga ttcgcgagct tcgtgcagta
    14821 gattatgcta aataaataag aaagagcagt tgaaaaatta ctgctttttt gttacactag
    14881 atagaaagac tgtaaaggat aatctggctt tttgccatta ttctagagaa atgttatttc
    14941 acagattgac taaaaggaga cacaatggca gaccgaggct tactaatcgt tttttctggt
    15001 ccttcagggg ttggaaaagg aacggttaga agagagattt ttgagagttc tgaaaaccaa
    15061 tttcaatact ctgtatcgat gacgacacgc gcacaacgtc ctggagaagt ggacggtgtc
    15121 gactatttct tccgtactcg tgaagaattt gaagagctga ttcgtcaagg acagatgttg
    15181 gaatacgcag aatatgtcgg taactactat ggaactcctc tgacctatgt caatgaaacc
    15241 ttggacaagg gaatcgatgt tttccttgaa attgaagttc agggtgctct tcaggtcaag
    15301 aaaaaggttc cagatgctgt ctttatcttc ctgacaccac cagatttgga tgaattgcaa
    15361 gatcgcttgg taggtcgtgg aacagatagt gcagaagtga ttgcccaacg aatcgaaaag
    15421 gccaaggaag aaattgccct catgcgtgag tatgattatg ccattgtcaa cgatcaggtg
    15481 cccctagctg ctgaacgtgt caaatgtgta attgaagcag aacacttctg tgtggatcgt
    15541 gtcattggtc actatcagga gatgttacca aaatctccaa ctacccgata aaatttagaa
    15601 aataggtaca agcaaatgat gttaaaaccc tctattgata ccttgctcga caaggttcct
    15661 tcaaaatatt cactcgtaat cttggaagca aaacgtgccc acgaattgga agcaggtgcc
    15721 ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc gcgctttaga agaaatcgaa
    15781 tcaggaaacg ttacaattca cccagatcca gaaggaaaac gcgaagcagt gcgtcgccgt
    15841 atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga aaatcaaaga gcaaattgct
    15901 aaagaaaaag aagatggtga aaaaatttaa ggttgggggg actcaatctt attttttcta
    15961 ttgcaagaat gtactgacaa ggaggaggtg agaagatggc cctagctaag attatcgtag
    16021 atgtgccctt gatgcagacg gaccagccct atagttacag gattccggag gaatttgagg
    16081 gaatgctgga agttgggatg cgggttcatg tgccttttgg taagggtaat cgcctgattc
    16141 aagggattgt tcttggtttg gagtcccaat cagatggaga agagatggag caagatttaa
    16201 aagatattgc agaggtgctg gatttttctc ctgttctcac gccagaacaa ctctggctgg
    16261 ctgaggagtt acgcaaatct gtcttctcct acaaaatttc tatcctcaag gccatgcttc
    16321 caggatttct gaattctagc tatgacaaga ttctctatcc tctggaaggc ttgagtcagg
    16381 aagaacgagt gcgcctgttt ggttcagaag attcgctagc cttttcttca ctagaccttg
    16441 ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct gcttggtctg gaatatcagg
    16501 cagtcgatca aaagaaggtc aagacccagt cttggtatga ggttgaccat gctcaattag
    16561 aaggtgttga gatttctaca cgtgccaaga aaaagttgga actgagagat tatctgctgt
    16621 ctcatccaga gagcgcttcc ttggctagct tgttagagtc ctactcgcga gagcaagtca
    16681 acttctttgt ggatcaaggt gctgttacca tagtccaaaa ggaagttcaa cgctcggctg
    16741 cttattttga aggaattgaa gcaagtagac ctttggagtt aaatccagaa caaagacagg
    16801 cgcgtgatgc ggttgtgagt tctattggca gttctcaacc tccctttcta cttcaaggga
    16861 ttacaggaag tgggaagacc gaggtttact tgcagattat ccaaggtgcc ctggataagg
    16921 gcaagacagc tattttgctg gtacctgaga tttccttgac tcctcagatg accgagcgtt
    16981 ttatagcacg ttttggggac aaggtagcca ttcttcactc aggattatcc aatggtgaaa
    17041 agtatgatga atggcgcaag gtggagcgtg gcgatgccca agttgttgtt ggtgccagat
    17101 ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat tattgatgaa gagcatgaag
    17161 cggcttataa gcaggacagc aatccccgtt accatgccag agaggtagct attttacggg
    17221 ctcagtataa tcaagcaact ctggtacttg gatctgcaac gccgagctta gagagccggg
    17281 cacgtgctgg caaaggcgtc tatcaacact tacgtctaac ccaacgtgcc aatcctttgg
    17341 ctacaatccc tgaggttcaa gtgattgact ttcgagacta tatcggacaa aatgagacgt
    17401 caaactttac gcctcctttg ctagaggcta tccaagaccg tctggttaaa aaagagcagg
    17461 tggttctcat gctcaatcgc cgtggttatt ctagctttgt catgtgtcgg gagtgtggga
    17521 cggtggatac ttgtcccaac tgcgatattt ctctgacctt gcatatggat accaagacta
    17581 tgaactgcca ttattgtggt ttctcgaagg atattcctca ggtctgtcct aactgtaaga
    17641 gccacagtat tcgttactat gggacgggaa ctcagaaggc ttatgatgag ctagcagaac
    17701 tctttcccca agttcgcatt ttgaggatgg atgtggatac gactcgaaag aaaggcagtc
    17761 accaagcctt gcttgaccag tttgggcgag gggaagcgga tattttactt ggtactcaga
    17821 tgattgcaaa gggtttggat tttcccaatg ttaccctagt aggagttcta aatgcggata
    17881 cggccttgaa tctgcctgat ttccgttctt ctgagagaac cttccagctc ttgactcagg
    17941 tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt cttgatacag tcctacaatt
    18001 cgcagcacta tgctattcga tttgccaagg atcaagatta cgaaggcttt tatgcctatg
    18061 aaatgggaat cagacgacaa ctcggctatc caccttacta tttcacgatt ggtattaccc
    18121 tttctcacaa gaaagaagaa gaggttttca aacgtgccta tgaagtcatg aacattttgc
    18181 ggtcaggctt gtcagagacc agtcccattc tggggccaac gccaaaaccg attgcccgta
    18241 cccgcaacct ctatcattac cagattttaa ttaaataccg tttagaagat gagctggggc
    18301 cgaccctcaa ccaggtcttg gccttgactc aagaacggga aaatagtgag ctccgtctca
    18361 gcattgacca tgagccgcag caatttttat aagaaggaga agatatgaca aaactaatct
    18421 ttatggggac ccccgacttt tcagcaacag tcttaaaagg acttttgaca gatgaccgtt
    18481 acgaaattct agccgttgtg acccagccaa accgtgctgt tggtcgtaaa aaagttatcc
    18541 aagaaacccc agtcaagcag gctgccaagg aagcaggact atctatctac caacctgaaa
    18601 aattatctgg aagtccagag atggaagatc ttatgaagct aggagcagat ggaattgtga
    18661 ctgctgcttt tgggcagttt ctcccaagca aactccttga tagcatggac tttgctgtca
    18721 acgttcatgc ctccctcctt cctagacacc gtggtggtgc gcctatccat tatgccttga
    18781 ttcaagggga tgaggaagct ggtgtgacca tcatggaaat ggttaaggaa atggatgcag
    18841 gagatatgat ttctcgtcgc agcattccga tcacagatga ggacaatgtt ggcaccttgt
    18901 ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga cactctgcct gcctatattg
    18961 ctggtgatat caaacctgaa ccgcaggata cgagtcaggt taccttctct ccaaatataa
    19021 agccagagga agaaaaactg gactggaaca aaaccaatcg tcaactcttt aaccaaattc
    19081 gtggaatgaa cccctggcct gttgcccata ctttccttaa gggcgaccgc tttaagattt
    19141 atgaagccct accagtagaa ggtcagggaa atccaggtga gattctctct atctgcaaga
    19201 aagaattgat tgtcgcaacg gctgaagggg ctctatccct caaacaagtg cagccagctg
    19261 gtaagcctaa gatggacatt gcttccttcc tcaacggagt tggacgtaca ttgactgtag
    19321 gagaacgatt tggtgactaa agtagaaacg gctagaagtt tagctctagc agtgctagag
    19381 gatgtttttg tgaatcaagc atattcaaat attgccttaa ataaacacct caaggggagt
    19441 cagctctctg cagcagacaa gggcttagtg accgagctag tctatggaac ggtagccctt
    19501 aaactgactc tggaatggta cctatcccac tttatcgaag acagagacca gttagacagc
    19561 tggctctatg tccttcttct catgagtgcc taccaactcc gctatttgga caagattcca
    19621 gatcatgctg tggtcaatga agcagtggaa ttggccaaac tccgtaaaaa aggcagtgaa
    19681 aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag gctggccaga tattgctagc
    19741 atcaagcgaa aaaacaagcg tgactccatt gcctattctc tcccagtttg gctagttgcc
    19801 aaactcaagg aagaatacgg agaggagaga gcaaaagcca tctttgaaag cctgttagtg
    19861 cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa aagaggaaat ccaagccttg
    19921 ttggaggcga ataattccct tttagcaacc actggtctgg ttaaggagca ggggcatttt
    19981 gcagggcata atttgtttgc gaatggagcc attaccatcc aagatgagtc cagtcagctg
    20041 gttgctccga cgcttgattt acaaggtgat gagcgagtgc ttgatgcctg tgcggctcca
    20101 ggtgggaaaa cagcccatat agcctcttat cttacgacag gtcaggttac tgctctggac
    20161 ttgtacgacc acaagttgga tttaattcaa gaaaatgccc aacgtctggg agttgcagat
    20221 cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg agttttttga ccaggattcc
    20281 tttgataaga ttttggtgga tgctccttgt tcaggaatcg gtcttttgcg ccgaaaacca
    20341 gatatcaaat acaataaaga aacggcagat ttcgcgtcct tgcaggaaat tcagttagaa
    20401 atattaggta gtgtttgtca aatactaggc aaaggtggta taataactta tagcacctgc
    20461 actatcgtct cagaggagaa ttttcaagtc gttaaggcct ttttagagag tcatcccgag
    20521 ttcgagcagg taaaactaga acatgaatgt aaggatatca tgaaagacgg ctgtatcctc
    20581 attacacctg aattgtatgg aagtgatgga ttcttcatca gtcaatttcg caagatatcg
    20641 gattaggaag gaactgacac atggaaattt cattattaac agatgttggt cagaaacgaa
    20701 caaataacca agactatgtc aaccactatg tcaatagagc tggacgtacc atgattattt
    20761 tagctgatgg gatgggaggt catcgcgcag ggaatatcgc tagtgaaatg gcggtcacag
    20821 acctgggtgt agcttgggtt gatacccaga tcgatacagt caatgaagtg cgtgaatggt
    20881 tcgcccatta cctagaaatt gaaaatcaaa agattcacca gcttggtcag gatgaagctt
    20941 acagaggcat gggaactact ttggaagtcc ttgctattat tgataatcag gctatctatg
    21001 ctcatattgg tgattcgcgt atcggcttga ttcgtggaga agaataccat cagttgacga
    21061 gtgatcattc tttggttaat gaattgctca aggctggtca attgacacca gaagaggcag
    21121 aagctcatcc gcaaaaaaat attatcaccc agtctattgg gcaaaaagat gaaattcagc
    21181 ctgattttgg gacagttatc cttgagtcag gtgactatct cttgctcaat agtgacggct
    21241 tgaccaacat gatttcaggc agtgagattc gtgatattgt aaccagtgat attcctttag
    21301 cagataaaac ggagacactt gttcgttttg ctaacaatgc aggaggttta gacaacatta
    21361 cggttgccct tgtttctatg aacgaggagg atgaagaatg atccaaatcg gcaagatttt
    21421 tgccggacgc tatcggattg tcaaacagat tggtcgagga ggcatggcgg atgtctacct
    21481 agccaaagac ttaatcttag atggggaaga agtggcagtg aaggttctga ggaccaacta
    21541 ccagacggac ccgatagctg tagctcgttt tcagcgtgaa gcgagagcta tggcagatct
    21601 agaccatcct catatcgttc ggataacaga tattggtgag gaagacggtc aacagtatct
    21661 tgcaatggag tatgttgctg gactagacct caaacgctat atcaaggaac attatcctct
    21721 ttctaatgaa gaagcagtcc gtatcatggg acaaattctc ttggctatgc gcttggccca
    21781 tactcgagga attgttcaca gggacttgaa acctcaaaat atccttttga caccagatgg
    21841 gacggccaag gtcacagact ttgggattgc tgtagccttt gcagagacaa gtctgaccca
    21901 gactaactcg atgttgggct cagttcatta cttgtcacca gagcaggcgc gtggttcgaa
    21961 ggcgactgtg cagagtgata tctatgccat ggggattatt ttctatgaga tgttgacagg
    22021 ccatatccct tatgacgggg atagcgcggt gaccattgcc ctccagcatt tccagaaacc
    22081 cctgccgtcc gttattgcag aaaatccatc tgtacctcag gctttagaaa atgttattat
    22141 caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg gtttcagaga tgtatgtgga
    22201 cttgtctagt agcttgtcct acaatcgtag aaatgaaagt aagttaatct ttgatgaaac
    22261 gagcaaggca gataccaaga ccttgccgaa ggtttctcag agtaccttga catctattcc
    22321 taaggttcaa gcgcagacag aacacaaatc aatcaaaaac ccaagccagg ctgtgacaga
    22381 ggaaacttac caaccacaag caccgaaaaa acatagattt aagatgcgtt acctgatttt
    22441 gttggccagc cttgtattgg tggcagcttc tcttatttgg atactatcca gaactcctgc
    22501 aaccattgcc attccagatg tggcaggtca gacagttgca gaggccaagg caacgctcaa
    22561 aaaagccaat tttgagattg gtgaggagaa gacagaggct agtgaaaagg tggaagaagg
    22621 gcggattatc cgtacagatc ctggcgctgg aactggtcga aaagaaggaa cgaaaatcaa
    22681 tttggttgtc tcatcaggca aacaatcctt ccaaattagt aattatgtcg gccggaaatc
    22741 ttctgatgtt atcgcggaat taaaagagaa aaaagttcca gataatttga ttaaaattga
    22801 ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg aagcaaagtc taccagaagg
    22861 tacgacctat gacttgagca aggcaactca aattgttttg acagtagcta aaaaagctac
    22921 gacgattcaa ttagggaact atattggacg gaactctaca gaagtaatct cagaactcaa
    22981 gcagaagaag gttcctgaga atttgattaa gatagaggaa gaagagtcca gcgaaagcga
    23041 accaggaacg attatgaaac aaagtccagg tgccggaacg acttatgatg tgagtaaacc
    23101 tactcaaatt gtcttgacag tagctaaaaa agttacaagt gttgccatgc cgagttacat
    23161 tggttccagc ttggagttta ctaagaacaa tttgattcaa attgttggga ttaaggaagc
    23221 taatatagaa gttgtagaag tgacgacagc gcctgcaggt agtgtagaag gcatggttgt
    23281 tgaacaaagt cctagagcag gtgaaaaggt agacctaaat aagactagag tcaagatttc
    23341 aatctacaaa cctaaaacaa cttcagctac tccttaaaag cagatggata atcaaaatga
    23401 gtaatcaatc tttgtcatga tttcatggca aagatttttt ttgagtccag atttgtgata
    23461 gaatagaggg agttgataaa aggaggaaag catggaagaa tcaaaagaat taaatgccgt
    23521 cattgatgtg attatgctag cggggactat tctccttaaa agtggctcag aaatccatcg
    23581 tgtagaagat accatgattc gaatcgcgca ttcgcagggg attgtggatt gcaatgtcct
    23641 tgccatgcct gccgctatct ttttctctat tgaaaatacc aatatttcgc gcatgaagcg
    23701 cgtgacctcc tcttcttata acatcgaaaa agtctgcgat gtgaaccaga tttctcgtca
    23761 gctagttggg gggcagattg acttagaaac agcctttaag caattgacgg ccttgcaagc
    23821 tcaacccctt ccctatacta agttgcaggt aactctggct gcgaccttta gtgctccttt
    23881 cttttcagtt atgtttagcg gaaatatcta cgacgcactt ggtgcaggag tggcgacctt
    23941 atttggtttt gccttttccc tctatgtgga aaaatttatc cgaattccct ttgtgacagc
    24001 ctttgctgga gcctttgtct ttgggataat tgcccagttt tgggctcgct acacaggttt
    24061 tccttcaacg gcagatttga ttatagctgg tgcggtcatg ccgtttgtac caggtattgc
    24121 cttgaccaat gcggtccgtg atattatgac caaccacata aactctggta tgagtaagat
    24181 gtttgaatcc ctgctcatta ccctcgcttt aggggcagga acttctgtcg ccttggtatt
    24241 gatgaactaa tatgacacta acaacctttt tattacaagc agtagcaagt tttcttgcca
    24301 ttatcacttt tttaatcgta ctcaatgtgc aacggtctat gctcttacct ggagggattt
    24361 tgggcatgac tgtctggcta atctatctct tgctcaagga accgaccaat gtcattgtag
    24421 ctaccttcat tgcagccatt attggttctt gtgtcagcca gattttaagt attctttata
    24481 agacacctgc tgtggtcttt atcttggcca ttttggcacc gctggttcca ggttatctct
    24541 cctaccgaac aactgccttt tttgtgacag gggactataa taaagcactg gcaagtgcga
    24601 ccttggttgt catgttggct ttggtaatct ctattggaat ggctagcgga acagtgattc
    24661 tcagactgta tcattatata aaaacacatc gagtatcgta gactttacag aaataaaaga
    24721 attttctgaa aaatgagata aataaattaa caacgctttc tatatgtgcg agaataccgc
    24781 acttatgaag aaattgcgac tgattttggt atccacgaaa gcaacttact ccgtcggagc
    24841 caatgggttg aagtaactct tgttcaaagg tggtgttacg atttcaagaa ctcctctcag
    24901 ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaaa
    24961 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    25021 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca tgatatgaag
    25081 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    25141 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    25201 aagctgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    25261 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
    25321 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    25381 ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc tactgacctt
    25441 gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga
    25501 gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg ataaggatgt
    25561 cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta
    25621 ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta
    25681 tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga
    25741 tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa
    25801 cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg
    25861 gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg
    25921 accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg
    25981 aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac
    26041 aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt aaggctgcgg
    26101 ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag
    26161 aagcctgcta tggggcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc
    26221 cggagtccaa ggtcttggtc attgcaagtg atattgccaa atacggtatt gaaactccgg
    26281 gagaacccac tcagggtgcc ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga
    26341 tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa
    26401 attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt
    26461 tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg
    26521 ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg
    26581 ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc
    26641 tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc
    26701 tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa
    26761 gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg
    26821 ataaagaccg cttgaacaag ctcaaccaac gaactgtctt atccgttgca gactatgaaa
    26881 aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg
    26941 aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg
    27001 aaaaataatg aagataagtt ggaatgggtt ttctaaaaaa tcataccaag agcgcctcga
    27061 gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga
    27121 acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct
    27181 gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt
    27241 gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc
    27301 aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag ccctttatca
    27361 agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga
    27421 gcttgccaat caagcctatc cttctatcgt taaacgtggg ggtggggcgc gtgacctgca
    27481 tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg tcgataccca
    27541 ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga
    27601 agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga ccgattctct
    27661 ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg atcaaggacg
    27721 agagattgcg gagaaaattg cgttggctag tcagtttgcg caggatgatc cttaccgagc
    27781 tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa
    27841 tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca
    27901 aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct
    27961 gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag
    28021 tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg tgtctatcgg
    28081 tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca
    28141 catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc
    28201 tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag cccagcgcta
    28261 tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta
    28321 aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg tgacttcctt
    28381 gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg
    28441 cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat
    28501 gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat
    28561 agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt
    28621 gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt
    28681 tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt
    28741 ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac
    28801 cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt ttcggtcaaa
    28861 ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga
    28921 aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt ccttctcaga
    28981 atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt ggtgttccaa
    29041 tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa
    29101 cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg
    29161 catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt tattgataac
    29221 ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac
    29281 cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt
    29341 ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt
    29401 caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag
    29461 aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga tccactgtca
    29521 cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta
    29581 agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg
    29641 tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg
    29701 gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt
    29761 ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta
    29821 gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca
    29881 tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa
    29941 tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg
    30001 gacagtagag aaggacaggt tgttcctcta caaagaccag attaggacat tccatcatgt
    30061 aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt
    30121 tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcctgt ccaccgacga
    30181 cagcatagta ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt
    30241 ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca
    30301 aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa
    30361 ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta
    30421 atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa tcatcacttt
    30481 ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga
    30541 ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg
    30601 gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa
    30661 tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc
    30721 attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct
    30781 tttatgttaa aaaagaggaa aaactgtcaa aggattatca taaaataaat acaggaaatc
    30841 aatcaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta accaaggttt
    30901 caaacttatt tttcaaggaa ttcctgatga aacagtcaaa aacaatcaat ctaaagcttg
    30961 cccactaagt ggatagaata tttttctgca aaacgcttga catattttta aaacatgata
    31021 aaataatagt cgtaagggcg aataaaatcg ctttcaaaca agaacaaaat gttatataag
    31081 gagatttttg caaatgaaca atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg
    31141 acgtgaaaat gtcaatagtg ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga
    31201 tgaagagaaa atcaataaag aagtgattga gaacttggaa aaagttcaag gtgctttctt
    31261 taactcaggg caataccaaa ttatctttgg tacaggtaca gttaacaaaa tgtacgatga
    31321 agttgttgta cttggcttac caacatcatc taaggatgac atgaaagcag aagttgctaa
    31381 acaagggaac tggttccaac gtgctatccg tacttttggt gatgttttcg ttccaatcat
    31441 cccagttatc gtagcgacag gtctcttcat gggtgtgcgt ggtcttttca acgctcttga
    31501 aatgccactt ccaggtgact ttgcaactta cacacaaatc ttgacagata cagccttcat
    31561 catcttgcca ggtttggttg tgtggtcaac cttccgtgta tttggtggaa atcctgccgt
    31621 tggtatcgtt cttggtatga tgcttgtctc tggctcactt ccaaacgctt gggcagttgc
    31681 tcaaggtggt gaagtaacag cgatgaactt ctttggtttc atccctgttg ttggtttgca
    31741 aggttccgtt cttccagcct tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt
    31801 ccgcaaggtt gttccagatg tcattgacct cttggtaaca ccattcgtga cacttttggt
    31861 catgtctatc cttggactct ttatcattgg accagttttc cacgttgttg aaaactacat
    31921 ccttattgct acaaaagcga ttcttagcat gccatttggc cttggtggtt tcttgattgg
    31981 tggggttcac caattgatcg tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt
    32041 gcaattactt gctgctgacc atgctaaccc attcaacgct atcatcacag ctgctatgac
    32101 agctcaaggt gctgctactg ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac
    32161 acttgctttc ccggctgctc tttctgcctt cctaggtatt acagagcctg ctatcttcgg
    32221 ggtgaacttg cgcttccgta aaccattctt cctttcattg attgctggtg caatcggtgg
    32281 tggattggct tctatccttg gacttgctgg tactggtaat ggtatcacca tcatccctgg
    32341 tacaatgctt tatgttggta acggacaact tccacaatac cttcttatgg tagctgtatc
    32401 atttgccctt ggttttgctc ttacttacat gtttggttac gaagatgaag tagacgcaac
    32461 tgcagctgca aaacaagctg aagtggctga agaaaaagaa gaagttgcgc cagcagctct
    32521 tcaaaatgaa acacttgtaa ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa
    32581 tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac caagccaagg
    32641 cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag ggcacgcttt
    32701 tggtttgaaa acaagaaatg gtgctgaagt tttgattcat gttggtattg atactgtatc
    32761 tatgaacggt gacggttttg aaacaaaagt tgctcaaggt gataaggtga aagttggcga
    32821 tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg atacaacaat
    32881 ggttatcgtt acaaatacag gtgactacgc ttcagtagct ccagtcgcaa caggttcagt
    32941 tgctaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta atgtgaaaac
    33001 gaacaaatga catatttgtt cgtttttatt agatagtaag atttacagag gaaaatctaa
    33061 aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa aacaagaggt
    33121 ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg
    33181 tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca actccaatcg
    33241 aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct ggtcttgcag
    33301 ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc tttatcacga
    33361 cgactccaaa accaaactgg gcaaatgtgg acttgcttgg tgcccttcgt cgcgccctaa
    33421 atgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa gtggttgccc
    33481 gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt acaggtatcg
    33541 gtgcaggtgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc
    33601 attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt
    33661 tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct cgtacaggtg
    33721 tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc tactatatcg
    33781 ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc tttggtggag
    33841 gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca tctcttctta
    33901 atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca gtcgcaggaa
    33961 atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa
    34021 aatccgcttg ggaaaccaaa cggatttttt acgtgtcaaa gcatttgcca gaaaaagtca
    34081 ataatatagg tcagaccgta ggtataaacc acgagggtaa agggtttggt cagaatgatg
    34141 atggtcatgt agcgcttgaa actcatcttg gtcagggcag ccagcataca gagaaagtca
    34201 gctgggctaa tgggccaaat catcataaaa ataaagaagc ggtcaaaacg attgccctta
    34261 tctagccagc cgatgtactt gtcgtaggtg cgcttgctga cgacagactg gacaaaggca
    34321 gctccgtata ggcgcactag ataaaagata atggcacagc caatcacgat gccgatatag
    34381 ttgtagatag tcccgatgat gtgcccgtag ataaagaccc cagccaccga ggtcaaggcc
    34441 cctggaatga tagggacgac agtctgtaaa atctgtaaaa agataaagag aggtggaccc
    34501 cagatgcctg cctgctggat aaaggcagag agggtttcct tggattgtaa aatcccagcc
    34561 tgataagccc aaatacagaa aatcaaactc ccaaccccac cgacaatcga tgagatattg
    34621 ataactcgct gcagaagggg agaaacagct ttcatttgtt tatcctgtga catgtaaact
    34681 cctcatagat agtatatttc tactatacca tattttggag gagaaagggg gaatgagtct
    34741 tttttgataa ggaatagaaa gtaaatagcc cttcgagact tagaataggt ctgtcaacta
    34801 aaggttatat gcattctagg tttcgaataa tcgcaattcc ataaatttaa aagtattcta
    34861 agtttcgaat agcttatctg ggataatttt gaggcattcg cgctttcgaa tagtcatttt
    34921 ccctaaagtt tatatgtatt ctgaagctag aaagactaaa atataaaagt agtaagagtc
    34981 tctctctgat ggacgtaatt tatggctagt atgaatcctt tgaattgtta gttaatttta
    35041 atattaatca gttctgaaat aattactaaa tatagttaga tggtgagtta attattgcta
    35101 aatttcaagt tcaagttagt catccagaag tcttctctgg gggacttgta gttcaagcat
    35161 tttttaggat agttgttaat ccacttttcg ataaatgcga cttcctttgt agttgttttc
    35221 ttagttccct gaggtaacca tctatgaatg agcctgttgt gattttcatt agatcctata
    35281 gtgatgtgca taatagatat agcagattga aactagaata gtatacatct acttctaaaa
    35341 cattgttaga aatcaatttg actgtcctga tcaatttgtc ctgtttttat ttcattttac
    35401 tatataatcc ttagaaaaca tatcggacaa gcggttgaat tccgttccgt ccattagtag
    35461 ataaaggatt actccttctt gaaatgacag atgaacttgt ttcttataaa aatgttgtct
    35521 gaaactatta gcctttttcc agaagtttta gaggaagaaa actttacgag gaaaaaggag
    35581 ttactcaaat aacaattcag gattaaaaat agacagttga ggagcggaag gtataaatta
    35641 agtttgctac tgtataatgg atttatcact aatactcttc gaaaatctct tcaaaccacg
    35701 tcagcttcgc cttgccgtag atatagttac tgacttcgtc agttctatcc acaacctcaa
    35761 aacagtgttt tgagctgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc
    35821 agcctacggc tagcttccta gtttgctctt tgcttttcat tgagtataaa agtgctccag
    35881 gccatatttt acacagcaat agtcttctaa aaatggacaa aaacattgta aaggctatca
    35941 aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa gatgctagaa gtaagaagtc
    36001 tagagaaaag ttttggctcc aagcaagttt tgtttggtat tgactttcaa gcgcgaccag
    36061 gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa aacaacgatt ttccatagta
    36121 ttttgaaatt cctagaatat cagggagaaa tcggtctgga tggtcaggat attcgtcagg
    36181 agacctatgc tcggattggt tatctgcctg aagaacgcag tctcatgcct aaattgacag
    36241 ttcttgaaca agttcgctac ttggcgactc taaaaggcat ggatgccaaa gaagtcaaag
    36301 aaaaactccc tcaatggatg aagaggttgg aagtgaaagg aaagctgaca gataaaatca
    36361 agagtctgtc aaaaggaaat cagcagaaga ttcagctcat tattactctg attcatgaac
    36421 cagacctgat tatcttggat gagcctttta gtggattgga cccagttaat acagaattgc
    36481 tcaaacaagt catttttcag gaaaaagagc gcggagcaac cattatcttt tctgaccatg
    36541 tcatgaccaa tgttgaggaa ctttgtgacg atattctgat gatccgagat ggccgtgtgg
    36601 tcttgcacgg accagttcag gatgtccgca atcaatacgg gaaaacgcgt ctctttgttt
    36661 caagtgaacg aagcaaggaa gaattggaaa atcttcctca tgtcaaacag gtgagcttga
    36721 ccaaacaagg cagttggaaa ttgattttgg aggatgagag cgctggaagg gaactcttcc
    36781 caatcttgac tcaaggtcaa tatatcgcaa catttgacca acaagcgcca actatcgatg
    36841 aaatctttaa actagaatca ggagtggaag tatgagaaat atgtgggttg taatcaagga
    36901 aacctatctt cgacatgtcg agtcatggag tttcttcttt atggtgattt cgccgttcct
    36961 ctttttagga atctctgtag gaattgggca tctccaaggt tcttctatgg ctaaaaataa
    37021 taaagtggca gtagtgacaa cagtgccatc tgtagcagaa ggactgaaga atgtaaatgg
    37081 tgttaacttc gactataaag acgaagcaag tgccaaagaa gcaattaaag aagaaaaatt
    37141 aaaaggttat ttgaccattg atcaagaaga tagtgttcta aaggcagttt atcatggcga
    37201 aacatcgctt gaaaatggaa ttaaatttga ggttacaggt acactcaatg aactgcaaaa
    37261 tcagcttaat cgttcaactg cttccttgtc tcaagagcag gaaaaacgct tagagcagac
    37321 aattcaattc acagaaaaga ttgatgaagc caaggaaaat aaaaagttta ttcaaacaat
    37381 tgcagcaggt gccttaggat tctttcttta tatgattctg attacctatg cgggtgtaac
    37441 agctcaggaa gttgccagtg aaaaaggcac caaaattatg gaagtcgttt tttctagcat
    37501 aagggcaagt cactatttct atgcgcggat gatggctctg tttctagtga ttttaacgca
    37561 tattgggatc tatgttgtag gtggtctggc tgccgttttg ctctttaaag atttgccatt
    37621 cttggctcag tctggtattt tggatcactt gggagatgct atctcactga ataccttgct
    37681 ctttattttg atcagtcttt tcatgtacgt agtcttggca gcattcctag gatctatggt
    37741 ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg atgattttga ttatgggtgg
    37801 tttttttgga gtgacagctc taggtgcagc tggtgacaat ctcctcttga agattggttc
    37861 ttatattccc tttatttcga ccttctttat gccgtttcga acgattaatg gctatgcggg
    37921 gggagcagaa gcatggattt cacttgctat tacagtgatt tttgcggtgg tagcaacagg
    37981 atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg gatgatttag ggatttggaa
    38041 aacctttaaa cgtgccttat cttataaata gaagagcctt gcgaaagcga ggtttttaaa
    38101 gatgaaaagg atggaatcac gaacctaatt atgtacacat tatgtaaaca ggttgcttga
    38161 aaactcaatt gtatagtgaa ctgaatctgg aataggataa tattacttct aaaacattct
    38221 tataaattga tttgaattcc aaaatcccat cgttccgttc ttatttcatt ttgcgatata
    38281 gtgaaaggaa ataagtcagc tcacaaaaaa cgcataatat caaggatttt taacacttga
    38341 tactatgcgt tttctaattt taaagacttt ttgcctggtc tcttttgttc tatgagtatg
    38401 ttacatatct aggtaaaaat tatttaaagc aaattaacct tatttctcaa gatgtagtag
    38461 gttccgagat aaaagatagc tatgaatatg agttctttaa caatggctat acctgctccc
    38521 atatagaaat ggtcattgag tcctaccagt gaattgacat agaaattaga actaagattg
    38581 aagaaaagtt caataaatcc aatgacgatt tggataccaa tgtaggctgc aacagcgagt
    38641 gctgtacggt attcattgaa aagctgtcca atggaaatag ccaggtagat gcagaggatt
    38701 cctgaaatgg tatttagtag gaaggatata cctgtaagaa agatctgagg gagatgtgtt
    38761 tctacaaatg taatcacata agaaagagga atccattctg gagctgttaa agccagaata
    38821 ataacagcac ttagagccaa tacagcggtg ctaatcaatg accagataaa ggcaccgatt
    38881 agtttggctg tgatgatatg gtgttcagaa actggcaagg tcaaagtcag atagccttgt
    38941 cggtcgtaga cactaccttt gaagcgttta ataatcaaga aaatggttga aatcgcaagt
    39001 gtaagcatca agccaccaaa gactgtagct agaaaaagta gcatagtagc ctgactttct
    39061 tggtaaggta gatttttaaa gccttgtgtc tgtattccga tgagggcaga aaggactagc
    39121 acggctgcgt agagggctaa ataccacttg ttaacatttt taaattcgta gtgaactaaa
    39181 ttccaaaaca taaataatct cctttgctta ggccttaaat tcctgacgga agagttggtc
    39241 aatggattca cctgactcgt agcgaatatc atctacattt ccttgacgga cgacttttcc
    39301 gtcttttagg aagacaattt catccaagat tggctcgata tcagaaatca agtgggtaga
    39361 aatcaaaacg gtagaagttg gtgagtagtt gttgataatg gtattgagga tataagcacg
    39421 ggctgctgga tccaccccac caatgggttc atccaaaaca tagagacgag catcacggct
    39481 cataaccaaa atcagttgaa ccttttcttt gtttcctttt gatagtttct tgagacgact
    39541 attttcatca atgcccaggt ctgcaagtag atgatgagcg cgttcaagat tgaaatcttt
    39601 atagaaggtc ttgaagtagg ttagggcttc tttgaccttc atttgctcat tgagataggt
    39661 cgtatcaggc aaataagcta caacggcctt ggttgctggg cttgggtcca tgtcgttgat
    39721 gaggacacgt ccttgatctg gttgtaagag gccattaatt agtttaatca gggttgtttt
    39781 tcctgagccg tttggcccaa gaaggccgac aatttttcca gctggaatgt caagagaaac
    39841 attttcaagg gctggtgttg ctccatatga tttggataca ttttcaaata ctagtaatga
    39901 cataggctta aactccttta atataatcac tgactacgcc tggtagttct tctttttcat
    39961 agccaaaatg gatcatggag gaaacgaagt gttccaattc ttcttctgat aattgtttgc
    40021 gtgactgagc gattagctcc ttatccttag tcacaaatcg tccagttgtt cgcttgctgt
    40081 agacaaatcc ttctcgttca aggtctgata aggctctttg gatggtattg ggattgacac
    40141 cagcctcgct agctagctcc ctcacggttg gaagttgttg attgggttcc agtgtatggg
    40201 aaacaatctg aagcttgatt ttctccataa tctgtaaata gatgggtttt ttgttgtcaa
    40261 atgtccagga catcttagtc tcctttctct tatccttttg tcttaactaa ataatacaac
    40321 aaaacaaaaa acttgtcaag caaaaagaag aattgttttg ggaatcgctt aaaaaatggt
    40381 ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg tccaaaatgt ggggctacca
    40441 agtcaagtgt tatcgatagt cgccaagcag aagaagggaa caccattcgt agaagacgtg
    40501 agtgcgacga atgccaacac cgttttacaa cctacgaacg agtagaagaa agaaccttag
    40561 tggttgttaa aaaagatggt acacgggaac aattctccag agataaaatc tttaatggga
    40621 ttatccgctc agcccagaaa cgtcctgtgt caagtgatga aatcaacatg gtagtcaatc
    40681 gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat tcaaagtgag gacattggtt
    40741 cactcgtcat ggaggagttg gctgaattgg acgagattac ctatgtacgt tttgctagtg
    40801 tctatcgtag ttttaaggat gtcagtgagt tagagagctt gctccaacaa atcacccagt
    40861 cctctaaaaa gaaaaaggaa agataaatga agccaattga ccgtttttct tatctaaaga
    40921 ataatcgggt gtcgcaagat acctcatctc tggtacagtg ctacctcccg attatcggtc
    40981 aggaggcact gagcctttat ctttatacaa tcagtttttg ggataatggt agaaaggaat
    41041 atcttttttc aagtatcctc aatcatctca actttgggat ggatagactg ataaaatcat
    41101 tgaaaatctt atctgctttt aatctcttga ccctctatca aaagggggat gtttatcagc
    41161 tagccctcca tgctcctcta tctagtcaag acttcttgga gcatcctgtt tatcgcagac
    41221 tcttagagaa aaagattggc gactctgctg tggaggattt gaaagttgaa agtgctgatg
    41281 gtgaagaaat acctgtctca ctcaatcaag tctttccaga attggcagaa ctaggcagtc
    41341 aagaagacct tggtctcaag aagaaagtgg ccaatgattt tgacttggaa cattttcgcc
    41401 agctgatggc tcgagatgga cttcgttttg cggatgagca gtccgatgtc ttaaacctct
    41461 ttgctattgc cgaggagaag aaatggactt ggtttgaaac ctatcaattg gccaagtcaa
    41521 cagctgtttc tcaggttatt tcaaccaaac gcatgcgtga aaaaattgct caaaaaccag
    41581 tttcctctga ctttaatcct aaggaagcaa ccattatcaa ggaagctaaa agtaagactg
    41641 ccctgcagtt cttagcagaa atcaagcaaa cacgcaaggg gaccattacc caaacagaaa
    41701 gagaactttt gcaacagatg gctggcttgg gcttgctgga cgaagtcatc aatatcattc
    41761 tcttgttgac ctttaataag gtggattcgg caaacatcaa tgagaaatat gccatgaagg
    41821 tggctaatga ctatgcctat caaaagatac attcagcaga agaggccgtt ttacgaattc
    41881 gtgagcgagg gcagaaaaca aaaacacaaa aacagaatca gactgcccca gcaaaaacca
    41941 atattcctaa atggagtaac ccagattata agaatgaaac cagcgaggaa actcgtctgg
    42001 aactagaacg taagaaacaa gaactattag ctcgattaga aaaaggagga gattagatgg
    42061 aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt ttattatcaa gatttggtcc
    42121 agaaaatcat gaaggaccct gatgttgcgg cttttatcca gcaagaatcc ttgactccag
    42181 aggaattaaa tcgcagtatc tccaagttta atcagtacat caccgagcgt gacaagtttc
    42241 tccgtgggga tacggattat attgccaaag gctacaagcc gattttggtt aagaatcatg
    42301 gctatgcaga tgtttcatat gaagaaactc ctgagctaat cgcggctgaa aaagaagcgg
    42361 ctattaagaa tcgtctcaag ctaatcaatc taccagccag tctcaaaaaa gctagtttgg
    42421 ctcaagttga tttggatgat ttgggacgct tgccagtttt tgaaaaacta ttagcctttg
    42481 tggagcaata tccagctatt cgaaaaggtc tttacttata tggagacttt ggtgtgggta
    42541 aaagtttcat ggtggcggcc ttagctcatg atttatcaga aaaacgtggt gtttcatcaa
    42601 ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa tgctatcagt gatggcaatg
    42661 ttaagacctt ggtggatgag attaagctgt ctgaggtcct gattttagat gatattggcg
    42721 ccgagcaatc aaccgcttgg gtgcgtgacg aaatcctgca ggtcattctc caatatcgga
    42781 tgcaggaaaa tttaccgacc tttttcacat ccaacttcaa ctttgaagat ttggagaagc
    42841 attttgcgaa agtgaaacat ggaaatgacg aaacctggga agccagacgg gtcatggaac
    42901 gcatccgtta tttggctgag gagactcgtt tagaaggagt aaaccgtcga tgacagaaac
    42961 cattaaattg atgaaggctc atacttcagt gcgcaggttt aaagagcaag aaattcccca
    43021 agtagactta aatgagattt tgacagcagc caagatggca tcatcttgga agaatttcca
    43081 atcctactct gtgattgtgg tacgaagtca agagaagaaa gatgccttgt atgaattggt
    43141 acctcaagaa gccattcgcc agtctgctgt tttccttctc tttgtcggag atttgaaccg
    43201 agcagaaaag ggagcccgac ttcataccga caccttccaa ccccaaggtg tggaaggtct
    43261 cttgattagt tcggtcgatg cagctcttgc tggacaaaac gccttgttgg cagctgaaag
    43321 cttgggctat ggtggtgtga ttatcggttt ggttcgatac aagtctgaag aagtggcaga
    43381 gctctttaac ctacctgact acacctattc tgtctttggg atggcactgg gtgtgccaaa
    43441 tcaacatcat gatatgaaac cgagactgcc actagagaat gttgtctttg aggaagaata
    43501 ccaagaacag tcaactgagg caatccaagc ttatgaccgt gttcaggctg actatgctgg
    43561 ggcgcgtgcg accacaagct ggagtcagcg cctagcagaa cagtttggtc aagctgaacc
    43621 aagctcaact agaaaaaatc ttgaacagaa gaaattattg tagaaagtga gaaattatgg
    43681 ccctaccaac tattgccatt gtaggacgtc ccaatgttgg gaaatcaacc ctatttaatc
    43741 ggatcgctgg tgagcgaatc tccattgtag aagatgtcga aggagtgaca cgtgaccgta
    43801 tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat gattgataca ggaggaattg
    43861 atgatgtcga tgctcctttc atggaacaaa tcaagcacca ggcagaaatt gccatggaag
    43921 aagcagatgt tatcgtcttt gtcgtgtccg gtaaggaagg aattaccgat gcagacgaat
    43981 acgtagcccg taagctttat aagacccaca aaccagttat cctcgcagtc aacaaggtgg
    44041 acaaccctga gatgagaaat gatatctatg atttctatgc tctcggtttg ggtgaaccat
    44101 tgcctatctc atctgtccat ggaatcggta caggggatgt gctagatgcg atcgtagaaa
    44161 atcttccaaa tgaatatgag gaagaaaatc cagatgtcat taagtttagc ttgattggtc
    44221 gtcctaacgt tggaaaatca agcttgatca atgctatctt gggagaagac cgtgttattg
    44281 ctagtcctgt tgctggaaca actcgtgatg ccattgatac ccactttaca gatacagatg
    44341 gtcaagagtt taccatgatt gatacggctg gtatgcgtaa gtctggtaag gtttatgaaa
    44401 atactgagaa atactctgtt atgcgtgcca tgcgtgctat tgaccgttca gatgtggtct
    44461 tgatggtcat caatgcggaa gaaggcattc gtgagtacga caagcgtatc gcaggatttg
    44521 cccatgaagc tggtaaaggg atgattatcg tggtcaacaa gtgggatacg cttgaaaaag
    44581 ataaccacac tatgaaaaac tgggaagaag atatccgtga gcagttccaa tacctgcctt
    44641 acgcaccgat tatctttgta tcagctttaa ccaagcaacg tctccacaaa cttcctgaga
    44701 tgattaagca aatcagcgaa agtcaaaata cacgtattcc atcagctgtc ttgaacgatg
    44761 tcatcatgga tgccattgcc atcaacccaa caccgacaga caaaggaaaa cgtctcaaga
    44821 ttttctatgc gacccaagtg gcaaccaaac caccaacctt tgtcatcttt gtcaatgaag
    44881 aagaactcat gcacttttct tacctgcgtt tcttggaaaa tcaaatccgc aaggcctttg
    44941 tttttgaggg aacaccgatt catctcatcg caagaaaacg caaataaaaa agtagaatct
    45001 ggaatgacag ttccggattt ttttgatata ataaaataat agaaaacgct atcaaaagaa
    45061 ggagggtgat gtcggtgatg gaacatttgt ttaaattctt acttttagca ccgtactttt
    45121 attttgataa ctggattgag aaggccaaca gaaatagtaa gttttttcca attttttatt
    45181 atttttactg gttttacatc cccttctatt ctctttttag ccttgcttgg acagttgttt
    45241 cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta tggggcattt
    45301 ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc tgtttcaaag
    45361 aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat tgatttatat
    45421 cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt acacgctatt
    45481 ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaac aatttaaaag
    45541 aggaggtttg tgatggaata cttgtttaaa atgataatct tattaccctg tttttacttt
    45601 ttcagctgga ttgaaaaggc aaacagagat agtaagattt tcccaatttt ttactatttt
    45661 tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt tttttcagtt
    45721 ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg tatttggcta
    45781 ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt caaaaaaatg
    45841 cttgacttga gacgggaact agggaagtct aaaggcggaa ggcattgatt tatactcttc
    45901 gaaaatctct tcaaaccacg tcaacgtcgc cttggattat atatgtaact gacttcgtca
    45961 gtcttatcta caacctcaaa gcagtgcttt gagcaacttg cggctagttt cctagtttgc
    46021 tctttgattt tcattgagta ttatattact ttctatttgt aggaggtggc ttatgaagat
    46081 tcctctctta actttggcaa ggcataaatt tgtttatgtc ttgcttactt tgctttttct
    46141 tgctttggtt tatcgtgatg ttttgatgac ttatttcttt tttgatattc atgcgcccga
    46201 tctagctaaa ttcgatggac aagcaattaa aaatgactta ttaaaatcag cattagattt
    46261 tcgtattctc cagttcaatc taggttttta tcaatcattt attattccaa tcatcattgt
    46321 tttgctaggt tttcaatata ttgagctgaa aaataaagtt ttacgattga gtattggaag
    46381 agaagtgagc tatcaagggt taaaaagaaa gttgactttg caagttgcaa gtatcccttg
    46441 tttgatatat ttagtgactg tgctgataat tgcaattata acctatttct ttgggacttt
    46501 ttctcctctt gaatggaatt ctctattttc tgatgggagt ggtttacaaa gactcctaga
    46561 tggagagata aaaagctatt tgttctttac ttgtgtccta ctaatcggta ttttcatcaa
    46621 tgcaatctat tttttacaaa tagttgatta tgtggggaat gtgactcgtt cggcaatcac
    46681 ctatttgatg tttctttggc ttggttctat gctgctctat agtgccttgc cttactatat
    46741 ggttcctatg acgagtttga tgcaagctag ctatggggat gtaagtttga tgaaactctt
    46801 tactccttat atccttcatg ttgtccctta tatggtactt aaaaaatatg aagataatgt
    46861 ttaagaattt taacaatatt tggctaaaga gaaagatcgt tttactactt cgtatagttc
    46921 tgatgatgat tttgataaac tatctattgt caacagcggt tcaaaagcag gatgctgtta
    46981 tctttttcaa gagagaattg atttcaattt tttcctataa tgactattct gaagcgaatt
    47041 tagaaatccc caaactcttg ttaaaccttt cgcttttcat ggtaggatgg ctctctgtca
    47101 ttttacttga aagtgatttg gcagaccatt accatcactt gattcgctat caatcaagct
    47161 cctttttcga ttatacaagg aaacgattgg ttgtcatttc taaatttttt actcaagatt
    47221 tgtttgtctg gtttcttggt ttacttccgc taggaattca tttcaaaaca gtcgcacttt
    47281 tctttttact tgctcagtta atgatgttgt acttactact gtcttatctg atagcactga
    47341 ttagtgcggg cgctggtttt tctttttttc tctatttttt ggcatttgtg ggacaagaat
    47401 ggatgatgga tcatattgta acagtgtatt tagtactctt aagcttatta gttatgttga
    47461 ttgttagtcg cttggaagag aaatttaaga aaggataaac gatgagactt gaaattataa
    47521 atggacagaa aatttatggg aaaagaccta ttttaaatca gttgaatttg gtgtttcaat
    47581 caggaaaaat ttatggactt aaaggtgata atggatctgg caagacggtt cttttaaaga
    47641 tacttgctgg ttatattaag cttgacaaag gaaaagttct tcaagatggt aaagtttacg
    47701 gggtaaaaaa tcattatatt caggatgcag gaattttaat tgaaaaagtc gagtttttat
    47761 ctcatttatc cctgagagaa aatttggaac tgttaaggta tttttcatct aaagttacgg
    47821 aaaaaagaat tgcctattgg attcaatact atgatttaca ggaatttgaa gacgttgaat
    47881 accgtcattt atccttggga acaaagcaaa aaatggcctt gattcaagcc tttatttcct
    47941 ctccttctat actctttctc gatgaaccta tgaatgcttt ggatgagaag agtgtgaggt
    48001 taaccaaaca ggtcatttta tcttacctga aaaaagaaaa tggtctggtt atcctgacgt
    48061 cgcacatatc ggaagatatt tcagaccttt gtacagatgt attagttgtc gaaaatggac
    48121 atatacaata tgtaaaggat atacaatcct aggagatggc ttatggcaca tctaaaatca
    48181 tttattacac gctattccaa ggtttatatt ggtttagttc tgctgatctg gctgtctttc
    48241 ttctttatcc cttgggatag agcgattctg ggggtaagga ttgacatctt catcatgcag
    48301 aaaatcttgc tagcttttgg aattctgtcc attctcatgg ccttgctgtc caagaaagtc
    48361 agtctctttg tttttggact gatttgctgt ctttctcttt ggattaactt atttatcaca
    48421 tttgccattt tgccgatttt tggcaattaa acagtcataa aagtcggaga ggttagcttg
    48481 aaaactaacc tctttttcct tttcaaaatg gggattcttc cttgaaaata atcagtaatt
    48541 gtgctaaaat taaaggaaca ttctaaaata ttcggaattt aaagtaagga aaaacatggc
    48601 taatatttta aaaacaatta tcgaaaatga taaaggagaa atccgtcgtc tggaaaagat
    48661 ggctgacaag gttttcaaat acgaagacca aatggctact ttgactgacg accaactaaa
    48721 agcaaaaaca gttgaattta aggaacgtta tcaaaatgga gaatcactgg attcattgct
    48781 ttacgaagca tttgcggttg tccgtgaagg tgccaaacgt gtcctaggtc tcttccctta
    48841 taaggttcag gtcatggggg ggattgttct tcaccatggt gacgtgccag agatgcgtac
    48901 aggggaaggg aaaaccttga ctgcgaccat gccggtatac ctcaatgccc tttcaggtaa
    48961 aggggttcac gtagttacgg ttaatgaata cctgtcagaa cgtgacgcga ctgagatggg
    49021 tgaattgtac tcttggcttg gtttgtcagt agggattaac ttggctacca aatctccaat
    49081 ggagaaaaaa gaagcctatg agtgtgatat tacttactca actaactcag aaatcggatt
    49141 tgactacctt cgtgacaaca tggtcgttcg cgccgaaaac atggtacaac gtccgcttaa
    49201 ctatgccttg gtcgatgagg ttgactctat cttgattgac gaggctcgta cacctttgat
    49261 tgtatcaggt gccaatgcgg ttgaaaccag tcagttgtat cacatggcag accactatgt
    49321 aaaatctttg aacaaagatg actacatcat cgatgtgcag tctaagacta ttggtttgtc
    49381 tgattcaggg attgacaggg ctgaaagcta cttcaaactt gaaaacctct atgacatcga
    49441 aaacgtggct ttgactcact ttatcgataa cgcccttcgt gccaactaca tcatgcttct
    49501 cgatattgac tatgtggtga gcgaagagca agaaatcttg attgtcgacc aatttacagg
    49561 tcgtaccatg gaaggtcgtc gttattctga tggattgcac caagctattg aagccaaaga
    49621 aggtgtgcca atccaggatg aaaccaagac atctgcctca atcacgtacc aaaacctttt
    49681 ccgtatgtac aagaaattgt ctggtatgac gggtacaggt aagactgagg aagaagaatt
    49741 ccgtgaaatc tacaacattc gtgttattcc aatcccaaca aaccgtcctg ttcaacgtat
    49801 tgaccactca gaccttcttt atgcaagtat cgaatctaag tttaaagcgg ttgtcgaaga
    49861 cgttaaggct cgttaccaaa agggtcaacc tgtcttggtt ggtacagtgg cggttgaaac
    49921 tagtgactac atttctaaga aattggttgc agctggtgtt cctcacgaag tcttgaatgc
    49981 caaaaaccac tatagagaag cccaaatcat catgaatgct ggtcaacgtg gtgccgttac
    50041 catcgcaacc aacatggcgg gtcgtggtac cgacatcaag cttggtgaag gtgttcgtga
    50101 acttggagga ctttgtgtta ttggtacaga acgtcatgaa agtcgtcgta tcgataacca
    50161 gcttcgtgga cgttcaggtc gtcaaggaga tccaggtgag tcacaattct acctatctct
    50221 tgaagatgat ttgatgaaac gttttggttc tgaacgcttg aagggaatct ttgaacgttt
    50281 gaacatgtct gaagaggcga ttgagtctcg catgttgacg cgtcaggttg aagcagctca
    50341 gaaacgtgtc gaaggaaata actacgatac ccgtaaacaa gtccttcaat acgatgatgt
    50401 catgcgtgaa caacgtgaga ttatctatgc tcaacgttac gatgtcatca ctgcagatcg
    50461 tgacttggca cctgaaattc aggctatgat caaacgcacg attgaacgtg tcgttgatgg
    50521 tcatgcgcgt gccaaacaag atgaaaaact agaggcaatt ttgaactttg ctaagtacaa
    50581 cttgcttcct gaagattcta ttacgatgga agacttgtca ggcttgtctg ataaggccat
    50641 caaggaagag cttttccaac gtgccttgaa ggtttacgat agtcaggttt caaaactacg
    50701 cgatgaagaa gcagttaaag aattccaaaa agttttgatt ctacgagtgg tggataacaa
    50761 gtggacagat catatcgatg cccttgatca attgcgtaac gcggttggac ttcgtggcta
    50821 tgctcagaac aaccctgttg ttgagtatca ggcagaaggt ttccgtatgt ttaatgatat
    50881 gattggttcg attgagtttg atgtgacacg cttgatgatg aaagcacaaa ttcatgaaca
    50941 agaaagacca caggcagaac gtcatatcag tacaacagcg actcgcaata tcgctgctca
    51001 ccaagcaagt atgccagaag atttggattt gagccagatt ggacgcaatg aactttgccc
    51061 atgtggttct ggtaagaaat ttaaaaactg tcacggtaaa agacaataaa atgagatagt
    51121 ttagaggcgg atatcttgtg aaaagtaaat ttttactggg tatccgtttg ctttataagg
    51181 agatgagtta tggtatttac agcaaaaagc tctaaaataa atatagaaga agttcgtgcc
    51241 ttgtcaaaat tagaaggtca ggctttggag aggaaatcac agcgcgatca agagctagaa
    51301 gccattatac gtggagaaga tcagcgaatt ctcttggtaa tcgggccatg ctcatctgac
    51361 aacgaagaag ctgtccttga atacgctaag cgtttggcag tcctacaaga agaagtggca
    51421 gatcgtatct ttatggttat gcgtgtttat actgccaaac cccgtaccaa cggagatggc
    51481 tataagggct tgattcacca gcctaacgcg acagaagcgc ctagtcttat caatggaatc
    51541 aaagccgttc gccatcttca ctatcgtgtc atcacagaaa cagggatgac aactgctgat
    51601 gaaatgcttt atcctgaaaa ccttccgctt gtagatgatt tgatttctta catggcagtt
    51661 ggtgcccgtt cagttgaaga ccagcaacac cgctttgtgg caagtggggc aggattttct
    51721 actggtttta aaaatccaac ctctggaaat ctcaatgtca tgtttaatgg gatttatgct
    51781 gctcaaaaca aacaaagttt ccttttctta ggaaaagaag tagaaacaac tgggaacccg
    51841 ctttcacacg ctattcttcg tggtgctctt aatgagtatg gaaaaaatat tcccaactac
    51901 tattatgaca atttaattga taccattgcc caatatgaga aaatgggctt ggaaaatcct
    51961 tttatcatca ttgataccaa tcatgacaat tctggtaagc agtatattga acagatccga
    52021 attgtccgcc agaccttgat taaccgtgct tggaatgaaa aaattaagca gttcgttcgt
    52081 ggttttatga ttgagtctta tctggaagat ggtcgacaaa atgagccaga agtatttggc
    52141 aagtctatca cagacccttg cctgggttgg gataacacag aagctcttgt cagagaaatt
    52201 tacaaaacgt taggagaata agatggcatt tattgaaaaa ggtcaagaaa tcgatatgga
    52261 agtcatcaag gctgaaaccc aattgtctgc ggaagccttg agactcaagg aaagccgtga
    52321 cagggaattg gcagatatta tttcagggga agatgaccgt attctcttgg tgattggtcc
    52381 ttgctcttct gataatgaag aggcggtctt ggaatatgct cgccgtttat ccgccttgca
    52441 aaagaaggta gcggacaaga ttttcatggt catgcgcgtg tatactgcta agcctcgtac
    52501 caatggagac ggctataaag gattggttca ccagccagat acttctaagg ctccaagcct
    52561 gattaacggt ttgcaggctg tgcgccagtt gcattaccgc gtgattacag agactggttt
    52621 gacaacggca gatgagatgc tttatccgtc aaatctgatc ttggtggatg acttggtcag
    52681 ctaccatgcc gttggagctc gttctgtgga agaccaagag caccgctttg tggcttctgg
    52741 gattgatgca ccagtaggga tgaaaaatcc aacctcagga aatttgggtg ttatgtttaa
    52801 cgccatctat gctgctcaaa acaagcaaac cttcctttat catgggcagg aagttgagac
    52861 atcaggtaat cctttggccc atgttatcct ccgtggagca gtcaacgagt atggcaatta
    52921 tatgccgaat tactactatg aaaacctact ccaagccatt gaacgctatg aaaccatggg
    52981 acttgaaaat ccttttatcc tcattgacac caaccatgat aactcaggca agcaatatat
    53041 ggagcagatt cgaattgttc gccagacctt gcagaatcgt gattggaatg agaaaattaa
    53101 aaagacggtt cgaggattta tgattgaatc ttacctagca gatggtcgtc aaaaccaacc
    53161 agagatcttt ggttgctcta ttactgaccc ttgcctaggt tgggaaaata cagaggcctt
    53221 ggtagaagag atttatgtta ccttgacaaa ataagtgaaa aggatggagt tggggaatct
    53281 caactccttt tgatgagaat gatagttgga cacggaattg acatcgaaga attggcttcg
    53341 atagaaagcg cagttacacg acatgaagga tttgctaagc gtgtactgac cgctcaggaa
    53401 atggagcgct tcaccagtct caaaggacgc aggcaaatag aatatttagc tggtcgctgg
    53461 tcggctaagg aggccttttc caaggctatg ggaacgggca ttagcaagct cggttttcag
    53521 gatttggaag tattgaacaa tgaacgtggg gcgccttatt ttagtcaggc accattttca
    53581 ggaaagattt ggctgtctat cagccacacc gatcagtttg tgacagccag tgtcattttg
    53641 gaggaaaatc atgaaagcta gtccacatag accaaccaag gctctgattc atctgggagc
    53701 tattcgacaa aatattcagc aaatgggggc tcatatccct caaggaacgc tcaagttggc
    53761 tgtggttaag gccaatgctt atggtcatgg agctgttgcc gttgccaagg caattcaaga
    53821 tgatgttgat ggcttttgcg tttccaatat cgatgaagcc attgaactca gacaagctgg
    53881 actcagcaag ccaatcctca ttttaggagt ttctgaaatc gaagctgttg ctctagctaa
    53941 agaatatgac ttcaccttga cagtggctgg actggagtgg attcaagcac tcttagataa
    54001 ggaagtggac ctaactggat tgacagtcca cctcaagatt gattcaggga tgggacggat
    54061 tggttttaga gaggcaagtg aggttgagca ggctcaagat ttgctccaac aacacggtgt
    54121 tcgtgttgaa ggaatcttta cccactttgc tactgctgat gaggaatcag atgactattt
    54181 taatgcccag ttagaacggt ttaaaactat tttagctagt atgaaggaag ttccagagct
    54241 ggttcatgct agcaattctg caacgactct ttggcatgta gagactattt tcaatgcggt
    54301 tcgtatggga gatgccatgt atggtctcaa tccaagtgga gcggtcttgg ctttgcctta
    54361 tgatttgata ccggccttga ccttggagtc tgctctggtt catatcaaga cagttccagc
    54421 tggtgcttgc atgggctatg gagcaactta tcaaacggat agcgagcaag tcatcgcgac
    54481 cgtgccaatc gggtatgcag atggatggac aagagacatg caaaatttct ctgtcttggt
    54541 agatggccaa gcttgcccaa ttgtcggcag ggtttcgatg gaccaaatca ctattcgatt
    54601 gcctaagcct tacccactcg gaaccaaggt aaccttgatt ggctccaatg gggataagga
    54661 aatcactgca actcaggtag cgacctaccg cgtaaccatt aactatgagg tggtttgcct
    54721 cctcagcgac cgtattccga gagaatatta ttagaaaaga aaggagtgga gcatgaatct
    54781 acatcaaccc ttgcatgtct tgcctggtgt gggaccaaag tcagcagaaa aatacgccaa
    54841 actaggaatt gaaaacttgc aagatctctt gctctacttt cctttccgtt atgaagactt
    54901 caaaaccaag caggtgctgg aactagaaga cggtgagaag gcagttcttt ctggtcaggt
    54961 agtgactcct gctagtgtcc agtattatgg tttcaagcgc aatcgcctgc gttttagtct
    55021 caagcaggga gaggtcgttt ttgcggtgaa tttctttaac cagccctatc tggctgataa
    55081 aatagagttg ggagcaaccc ttgctgtctt tggaaaatgg gaccgcgcta aggctagtct
    55141 gactgggatg aaggttctgg ctcaggtaga agatgacctc cagcctgtct atcgtctggc
    55201 tcagggaatc agtcaggcca gtctggtcaa ggtcatcaag acggcttttg atcagggact
    55261 ggacctcttg atagaagaaa atctgcccca gtctttacta gacaaataca aactcatgtc
    55321 ccgttgtcag gcagtccgag ctatgcattt tccaaaggat ttggcagaat acaagcaggc
    55381 tcttcgccgt atcaagtttg aggaactctt ttatttccaa atgcagttgc agatgctcaa
    55441 gtctgaaaat agagttcagg gaagtggtct ggttctgaat tggtctcagg aaaaagtgac
    55501 agcagttaaa gcaagtcttc cttttgccct gacccaagct caggaaaaga gtttgcagga
    55561 aattttaact gatatgaagt ccgaccacta catgaatcgt ctcctacaag gagatgtggg
    55621 gagcggaaaa acggtagtcg ctggcttggc catgtttgcg gcagtgacag caggttatca
    55681 ggctgcccta atggtaccaa cagaaatcct cgcagagcaa cactttgaga gtttacagaa
    55741 cctttttccc aatttgaaac tggctctctt gacaggttcc ttgaaagctg cagaaaagag
    55801 agaggtcttg gagaccattg ccaagggtga ggctgatttg attataggaa ctcacgctct
    55861 gatacaagat ggggtggagt atgctcgtct tggtttgatt attatcgatg agcagcaccg
    55921 ttttggtgtg gggcaaaggc gtattttacg ggaaaaaggc gacaatccag atgtcctcat
    55981 gatgacggcg actcccattc cacggacgct tgccatcaca gcctttggag atatggatgt
    56041 ttccattatc gaccagatgc cagcaggtcg gaagcctatt gtgacgcgct ggatcaaaca
    56101 tgagcaacta cctcaggtct tgacttggtt agagggggaa attcaaaaag gttcccaagc
    56161 ctatgtcatc tctcctttga ttgaagaatc agaagctcta gatttgaaaa atgccattgc
    56221 cttatcagag gagttgacga ctcattttgc aggcaaggca gaggtggctc ttctacatgg
    56281 taggatgaag agtgacgaaa aagaccagat catgcaggat ttcaaggaga gaaagacgga
    56341 tattctggtt tcgacgacgg ttattgaggt tggggtcaat gttcccaatg cgactgtcat
    56401 gattatcatg gatgccgatc gcttcggtct cagtcaactt caccagctta gaggtcgtgt
    56461 cggtcggggg gacaagcagt cctacgctgt tctcgttgcc aatcccaaga cggattctgg
    56521 gaaagaccgc atgcgcatca tgacagaaac gaccaatgga tttgtccttg cggaggaaga
    56581 tttgaaaatg cgtggttctg gtgagatttt tggaaccaga cagtcaggac ttccagagtt
    56641 ccaagtggct gatattatcg aagattttcc gattttagaa gaagcaagaa aggttgctag
    56701 ctacattagt tctatagaaa cttggcaaga agatccagag tggcgcatga ttgcccttca
    56761 tctggaaaag aaagaacatc tggattaagc tttctctaag gaaaacttaa gctagttttt
    56821 agatttggct cttatactaa agtcatcaaa aagaaacgag gactctcata tgacagtaac
    56881 gattaaagta aattaccaaa ccactttcca aaagaaggaa gca
//
LOCUS       DAVLBN010000005        56641 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLBN010000005 DAVLBN010000000
VERSION     DAVLBN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.005"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VXC24_000275"
     CDS             complement(<1..137)
                     /locus_tag="VXC24_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0492452.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            314..1759
                     /gene="cps4A"
                     /locus_tag="VXC24_000276"
     CDS             314..1759
                     /gene="cps4A"
                     /locus_tag="VXC24_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0492453.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1761..2492
                     /locus_tag="VXC24_000277"
     CDS             1761..2492
                     /locus_tag="VXC24_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0492454.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNGKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2501..3193
                     /gene="cpsC"
                     /locus_tag="VXC24_000278"
     CDS             2501..3193
                     /gene="cpsC"
                     /locus_tag="VXC24_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV0492455.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFTYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNILIGFLAGVIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLNKLK"
     gene            3203..3886
                     /gene="cps4D"
                     /locus_tag="VXC24_000279"
     CDS             3203..3886
                     /gene="cps4D"
                     /locus_tag="VXC24_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HEV0492456.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVS
                     PGEGKTTTSVNIAWSFARAGYKTLLIDGDTRNSVISGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEANKRDVQKAKQQLKQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKK"
     gene            3902..5269
                     /locus_tag="VXC24_000280"
     CDS             3902..5269
                     /locus_tag="VXC24_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0492457.1"
                     /translation="MDEKGLKIFMAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYVSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLNKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVSYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5273..6016
                     /locus_tag="VXC24_000281"
     CDS             5273..6016
                     /locus_tag="VXC24_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV0492458.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            6013..6837
                     /locus_tag="VXC24_000282"
     CDS             6013..6837
                     /locus_tag="VXC24_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV0492459.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6839..7717
                     /locus_tag="VXC24_000283"
     CDS             6839..7717
                     /locus_tag="VXC24_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0492460.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNYNAKQIVIIDNFSNNGTG
                     EKLQELYESDLEIDVLINHENAGFARGNNVAYQFAKEKYNPDFMVIMNNDIEIETENF
                     EKIVTDIYREEKFHLLGPDIFSTTYQLHQNPKRLTHYTYGEVKALNEKFKKGSQVSLA
                     LKIKCWLKASKVLRTAIYQNRRKKGSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIRVLHHQNVATNQVYTNLLEKTLFSNKCNF
                     KSTSYFLKLMKENEDV"
     gene            7718..9055
                     /locus_tag="VXC24_000284"
     CDS             7718..9055
                     /locus_tag="VXC24_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV0492461.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            9078..10499
                     /locus_tag="VXC24_000285"
     CDS             9078..10499
                     /locus_tag="VXC24_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492462.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10563..11651
                     /gene="wecB"
                     /locus_tag="VXC24_000286"
     CDS             10563..11651
                     /gene="wecB"
                     /locus_tag="VXC24_000286"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV0492463.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11690..12559
                     /gene="rfbA"
                     /locus_tag="VXC24_000287"
     CDS             11690..12559
                     /gene="rfbA"
                     /locus_tag="VXC24_000287"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0492464.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12560..13156
                     /locus_tag="VXC24_000288"
     CDS             12560..13156
                     /locus_tag="VXC24_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0492465.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13166..14215
                     /gene="rfbB"
                     /locus_tag="VXC24_000289"
     CDS             13166..14215
                     /gene="rfbB"
                     /locus_tag="VXC24_000289"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0492466.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14281..15132
                     /gene="rfbD"
                     /locus_tag="VXC24_000290"
     CDS             14281..15132
                     /gene="rfbD"
                     /locus_tag="VXC24_000290"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0492467.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15208..15642
                     /locus_tag="VXC24_000291"
     CDS             15208..15642
                     /locus_tag="VXC24_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492468.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAENQVITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            15715..15972
                     /locus_tag="VXC24_000292"
     CDS             15715..15972
                     /locus_tag="VXC24_000292"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492469.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLMEDFFA"
     gene            16018..16164
                     /locus_tag="VXC24_000293"
     CDS             16018..16164
                     /locus_tag="VXC24_000293"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492470.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            16235..16393
                     /locus_tag="VXC24_000294"
     CDS             16235..16393
                     /locus_tag="VXC24_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0492471.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            16749..17225
                     /locus_tag="VXC24_000295"
     CDS             16749..17225
                     /locus_tag="VXC24_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0492472.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            17263..17568
                     /locus_tag="VXC24_000296"
     CDS             17263..17568
                     /locus_tag="VXC24_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0492473.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            17616..19091
                     /locus_tag="VXC24_000297"
     CDS             17616..19091
                     /locus_tag="VXC24_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0492474.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            19117..19194
                     /locus_tag="VXC24_000298"
                     /pseudo
     CDS             19117..19194
                     /locus_tag="VXC24_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            19396..26097
                     /locus_tag="VXC24_000299"
     CDS             19396..26097
                     /locus_tag="VXC24_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0492475.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(26345..27201)
                     /locus_tag="VXC24_000300"
                     /pseudo
     CDS             complement(26345..27201)
                     /locus_tag="VXC24_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27412..27771)
                     /locus_tag="VXC24_000301"
     CDS             complement(27412..27771)
                     /locus_tag="VXC24_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0492476.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            27863..28819
                     /locus_tag="VXC24_000302"
                     /pseudo
     CDS             27863..28819
                     /locus_tag="VXC24_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            28803..29360
                     /locus_tag="VXC24_000303"
     CDS             28803..29360
                     /locus_tag="VXC24_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0492477.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            29353..29607
                     /locus_tag="VXC24_000304"
     CDS             29353..29607
                     /locus_tag="VXC24_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492478.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            29619..31673
                     /locus_tag="VXC24_000305"
     CDS             29619..31673
                     /locus_tag="VXC24_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0492479.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            31852..32712
                     /locus_tag="VXC24_000306"
     CDS             31852..32712
                     /locus_tag="VXC24_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0492480.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            32923..33633
                     /gene="ccdA2"
                     /locus_tag="VXC24_000307"
     CDS             32923..33633
                     /gene="ccdA2"
                     /locus_tag="VXC24_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0492481.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            33653..34219
                     /locus_tag="VXC24_000308"
     CDS             33653..34219
                     /locus_tag="VXC24_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0492482.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            34230..35342
                     /gene="msrB"
                     /locus_tag="VXC24_000309"
     CDS             34230..35342
                     /gene="msrB"
                     /locus_tag="VXC24_000309"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0492483.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            35610..36347
                     /locus_tag="VXC24_000310"
     CDS             35610..36347
                     /locus_tag="VXC24_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492484.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            36344..38035
                     /locus_tag="VXC24_000311"
     CDS             36344..38035
                     /locus_tag="VXC24_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0492485.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASITSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            38151..38714
                     /locus_tag="VXC24_000312"
     CDS             38151..38714
                     /locus_tag="VXC24_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0492486.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            38736..44678
                     /locus_tag="VXC24_000313"
     CDS             38736..44678
                     /locus_tag="VXC24_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0492487.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            44739..46460
                     /gene="pabB"
                     /locus_tag="VXC24_000314"
     CDS             44739..46460
                     /gene="pabB"
                     /locus_tag="VXC24_000314"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0492488.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            46461..47078
                     /locus_tag="VXC24_000315"
     CDS             46461..47078
                     /locus_tag="VXC24_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0492489.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            47128..48126
                     /locus_tag="VXC24_000316"
     CDS             47128..48126
                     /locus_tag="VXC24_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0492490.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            48253..49212
                     /locus_tag="VXC24_000317"
     CDS             48253..49212
                     /locus_tag="VXC24_000317"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0492491.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            49309..50148
                     /locus_tag="VXC24_000318"
     CDS             49309..50148
                     /locus_tag="VXC24_000318"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0492492.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50196..50366)
                     /locus_tag="VXC24_000319"
     CDS             complement(50196..50366)
                     /locus_tag="VXC24_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0492493.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            50487..51371
                     /gene="miaA"
                     /locus_tag="VXC24_000320"
     CDS             50487..51371
                     /gene="miaA"
                     /locus_tag="VXC24_000320"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0492494.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            51364..52602
                     /gene="hflX"
                     /locus_tag="VXC24_000321"
     CDS             51364..52602
                     /gene="hflX"
                     /locus_tag="VXC24_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0492495.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            52595..53218
                     /locus_tag="VXC24_000322"
     CDS             52595..53218
                     /locus_tag="VXC24_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0492496.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            53233..54162
                     /locus_tag="VXC24_000323"
     CDS             53233..54162
                     /locus_tag="VXC24_000323"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0492497.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            54183..54938
                     /locus_tag="VXC24_000324"
     CDS             54183..54938
                     /locus_tag="VXC24_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0492498.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(54992..55900)
                     /locus_tag="VXC24_000325"
     CDS             complement(54992..55900)
                     /locus_tag="VXC24_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0492499.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            55964..56233
                     /locus_tag="VXC24_000326"
     CDS             55964..56233
                     /locus_tag="VXC24_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0492500.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            56233..56613
                     /locus_tag="VXC24_000327"
     CDS             56233..56613
                     /locus_tag="VXC24_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0492501.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
BASE COUNT        17639 a         9977 c        12333 g        16692 t
ORIGIN      
        1 tttcctttct gttgataggc tagtagcaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      241 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      301 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      361 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      421 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      481 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      541 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      601 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      661 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      721 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      781 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      841 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      901 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      961 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
     1021 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
     1081 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1141 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1201 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1261 ttcgtttttg aaattgattg atttgttggg tggaattgat gtttataatg atcaagaatt
     1321 tactgcccat acgaatggaa agtattaccc tgcaggcaat gttcatcttg attcagaaca
     1381 ggctctcggt tttgttcgtg agcgctactc actagcagat ggcgatcgtg accgcgggcg
     1441 caatcaacaa aaggtgattg tggctatcct tcaaaaatta acgtcaaccg aagcactgaa
     1501 aaattatagc acgatcatta atagcttgca agattctatc caaacaaata tgccacttga
     1561 gactatgata aatttggtca atgctcagtt agaaagtgga gggaattata aagtaaattc
     1621 tcaagattta aaaggtacag gtcggacgga tcttccttct tatgcaatgc cagacagtaa
     1681 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1741 tgtgatggag ggtagataaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1801 acggtcccaa gtcaagagag gaaagcaagg ctctcttgac agaatcctac aggcaggggg
     1861 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1921 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtagca gatgatttag
     1981 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     2041 aagaaattcc taccctcaat gatagtcgtt atgccttgat agagtttagt atgaacactc
     2101 cttatcgcga tatccatagc gccttgagca agatcttgat gttgggaatt actccagtca
     2161 ttgcccacat tgagcgctat gatgctcttg aaaataacgg aaaacgtgtt cgtgaactga
     2221 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2281 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2341 atgtagttgc aagtgatatg cacaatttag acagtagacc tccatatatg caacaggcat
     2401 atgatatcat tgctaagaaa tatggagcga aaaaagcgaa agaacttttt gtagataatc
     2461 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2521 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2581 agtggcaatt ataacttctt cggttgcttt tacctacagt acttttgtta tcaaacctga
     2641 gtttactagt acgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2701 aaccaatcaa gacttgcagg caggaacata cttggttaaa gactatcgtg aaattatcct
     2761 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaagg
     2821 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2881 taatgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2941 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     3001 ggcgatatcc ccgtcttcgc caaatattaa acgcaatata ctaattggtt ttttggcagg
     3061 ggtgattgga actagtgtta tagttcttct tcttgaactt ttagacactc gtgtgaaacg
     3121 tccggaagat atcgaagata cactgcagat gacacttttg ggagttgtac caaacttgaa
     3181 taagttgaaa taggagagag agatgccgac attagaaata gcacaaaaaa aactggagtt
     3241 cattaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3301 taaactaaaa gtaatttccg ttacttctgt tagccctggg gaaggaaaaa caactacttc
     3361 cgtaaatata gcatggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3421 tactcgaaat tcagttatat caggattttt taaatctcgt gaaaaaatta cagggctaac
     3481 agaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3541 tttatttgta gttcaatcgg gatctgtatc accaaaccct acagccttgt tacaaagtaa
     3601 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3661 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3721 cttggtaaca gcaacaggtg aggcgaataa acgtgatgtc caaaaagcga aacaacaatt
     3781 aaaacaaaca ggaaaactgt tcctaggggt tgttttaaat aaattagata tctcggttga
     3841 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaataattta ggaaagattc
     3901 tatggatgaa aaaggattga aaatttttat ggcagtatta cagagtatta ttgtcatttt
     3961 attggtttat tttcttagct ttgttagaga gacagaactt gaacgttctt cgatggttat
     4021 actatacctt ctccactttt ttgtattcta tgttagttcc tatggtaaca atttttttaa
     4081 aagagggtac ctagttgagt ttaatagtac tataagatat atttttttct ttgcaatagc
     4141 tataagtgta ttaaactttt ttatagcgga acggtttagt atctctagaa gaggaatggt
     4201 atacttctta actttagaag gaatatcctt atacttgtta aatttcttag taaagaaata
     4261 ttggaaacat gtgtttttta atctaaaaaa tagcaagaaa attttactgt taacagtaac
     4321 gaaaaatatg gaaaaagttc ttgataaatt gctagaatct gatgaacttt catggaagtt
     4381 ggtagcagta agtgttttga ataaatctga ttttcaacat gataaaatac ctgtaattga
     4441 aaaggaaaaa attattgaat ttgcaacgca tgaagttgtg gatgaggtgt ttgtcaatct
     4501 tccaggagag agctacgata ttggagaaat tatctctagg tttgagacaa tggggataga
     4561 tgtaactgta aatcttaaag catttgataa gaatttgggt cgcaataaac aaattcatga
     4621 gatggtagga ttgaatgtag tcactttctc tacaaatttt tataaaacta gtcatgtgat
     4681 ttcaaagaga attctcgata tttgtggtgc cactattggc cttattcttt ttgctatagc
     4741 tagtctagtt ttagttccat tgattcgtaa agatggcgga ccagctattt ttgctcaaac
     4801 tcgtataggg aaaaatggtc gacattttac cttttataaa ttccgttcga tgaggatcga
     4861 tgctgaagct atcaaagaac agttgatgga tcaaaatacg atgcaaggtg gtatgtttaa
     4921 gatagacaat gatcctcgtg ttacaaaaat tggtcgcttt attcgtaaaa ccagtttaga
     4981 tgaattgccg cagttttgga atgtctttat aggagatatg agtttggtgg gaacacgtcc
     5041 acctacagta gacgagtatg atcagtatac tccagaacaa aaacgtcgac tcagctttaa
     5101 acctggtatt acaggtttat ggcaggttag cggccgtagt aaaataaccg attttgacga
     5161 tgttgtaaaa ttagatgtgt cttatattga taattggaca atctggaaag atattgaaat
     5221 tttgcttaaa actgttaaag ttgtatttat gagagatgga gcgaagtgag gaatgaggga
     5281 tagaatccaa cttttaggtg taacaattga tttgcttacg atgaatgaaa cgatagatat
     5341 tgtagaacaa tatgtattag aaaaaagacc actacacttg atgggggtga atgctgataa
     5401 aattaatcag tgtcatacag atgagaaaat caaaaaaatc gttaatgagt caggaatcat
     5461 taatgcggat ggagcatcag ttgttcttgc aagtaagttt ttaggaacgc ctgttcctga
     5521 acgagtagcg ggtattgatt tgatgcaatg tcttttagag ttgtcaaata aaaaaggata
     5581 ttcagtttac ttttttggag caaaagaaga agttttgcaa gatatgctca aagtatttaa
     5641 gagagattat ccaaatttga tagttattgg acacagaaat ggctattttt ctgaagagga
     5701 tgaacaagct attcaagaag atattcgtga aaagaaccct gattttgtgt ttattggaat
     5761 tacgtctcct aaaaaagaat atattattca aaaatttatg gatagtggcg tcaattcggt
     5821 atttatggga gttggcggta gttttgatgt cttgtctggt catatccaac gagcacctct
     5881 atggatgcaa aagtcaaatt tagagtggtt attccgtgta gctaatgagc ctaaacgtct
     5941 ctttaaacgt tattttgtag ggaatatttc attcatagga agagttttaa aagcaaaaag
     6001 aggtgtaaaa tattgaacca gacagagatg attcgcttaa ttcaaaaagt tgaattagat
     6061 gctataaaag agtttaaaaa aatctgtgaa gagaatgata tagatttttt cctccgcggt
     6121 ggtagtgtac ttggtgcggt caaatacgac ggctttattc catgggatga tgatatggat
     6181 atcgctgtcc ctcgtgaagc atacgacaaa cttccaagtg ttttcaaaga tagaattatc
     6241 gctgggaaat atcaggttct tacttatcaa tactgtgata cgttgcattg ctactttcct
     6301 cgactattcc ttttagaaga tgaaagaaaa cgtttgggct tgccacgaaa taccaatcta
     6361 ggattgcatt tgattgatat cattccttta gatggagcac caaatcattc ggttttaaga
     6421 aagatttact ttggcaaagt atactggtat cgttttttag caagtttagg aacaacttat
     6481 gttggcgacc atgtggatat gcattccact aagcaaaaac taattattgg tttctttaaa
     6541 aaactaggat ttgcaaaact atttcctcaa aattctgtat acagacgctt ggataatctc
     6601 tataaaaagt atgattggaa aaagcagaag tatgcgggga ctatcaatgc ttctttattt
     6661 gctaaagaag ttatgccagt agagatttgg ggagaaggag tagagaagcc ttttgaggat
     6721 actttcttta aagttccaac ggagtatgat cgctacctga aaagacttta cggagaaaac
     6781 tatctttacg aagagcctag tgatgatgaa aagaaatcgc atttaggagg acactaattt
     6841 gttttgttat attattttgc attacaaagt cttagaagaa actatttctt gtgttaaatc
     6901 tataaaagaa ggcaattata atgcaaagca aatcgttatt attgataatt tttctaataa
     6961 tggtactggt gaaaaactac aagagcttta tgaatcagat ttagaaattg atgttttgat
     7021 taaccatgaa aatgctggtt ttgctcgtgg aaataatgtg gcttatcaat ttgctaagga
     7081 aaagtataac cccgatttca tggttatcat gaataacgat attgagatag aaacagaaaa
     7141 ttttgaaaaa attgtgacag atatctatcg tgaggaaaaa ttccatttgc tcgggccaga
     7201 tatcttctcg actacttacc aacttcacca aaacccaaaa cggttgacac attatactta
     7261 tggagaagtt aaagctctaa atgaaaaatt taaaaaaggg agccaagtta gtctagcttt
     7321 aaaaatcaaa tgttggttga aagctagtaa agttcttcga acagcaatct atcaaaatag
     7381 acgtaaaaaa ggatcagtag actatagaaa acaggtagaa aacccaattc ttcatggttc
     7441 ttttattgta tattcgagag attttatcga aaaagaggag tatgctttta accctaacac
     7501 cttcttctac tatgaaacag agatattaga ttatgaagct gaattaaaag gatacaagag
     7561 aatttataca cctaaaatta gagttttgca ccatcaaaat gttgcaacta atcaagttta
     7621 cacgaacttg ttagaaaaaa ccttgttttc aaataaatgc aactttaaat ccaccagtta
     7681 ttttttgaag ttgatgaaag aaaacgagga tgtttaaatg agttatttat ttttactttg
     7741 ccttacatta ttcttattga ctatattcta tttctttgct tttattcaag atttaattgc
     7801 tcctccagta gttatgtctg taatgtttct aattagttca gtatttgcac tggttaattc
     7861 aaaaaactgg aatattgaat atagtggaat agcctatatt ctcataatta gtggtattat
     7921 tatattttcg cttcctttaa tggcattaaa atcacctaat tttaatactg aggttaagat
     7981 tgctgatcga ttaattgata tccaattttg gaaaattgct ctaactatta taattgatct
     8041 ctttattttg tatctttaca ggaaggaaat atataacctt gttcttagta atggatatac
     8101 ggggtcaaat attcagtggt tttttagaaa tgcaacgagt tatgaaggtg aattgacagt
     8161 gcgaactttt attcgagttc tcattcgtgt tattgacgta tctgcttata tttttggata
     8221 tacttttatt aataattttc ttatctatcg ccataaacgc cctaaagaca tattactttt
     8281 agtaccttta ttaatattta tttcaaaaac tttaatatca ggaggccggc aagatattat
     8341 taaaattctg attgcctatg taatcatgat gtatatccaa caaaaacgga aagttggatg
     8401 gaatagagtc atatctcata aatatattca ccttggattt gttggtttaa tagcaggtat
     8461 tccagcattt tactactctt tgtttttagc cggtcgttca acgactagga cgctatttga
     8521 gagtgtttcg acctatctag gaggctcaat tcagcatttt aatcagtata ttgaaaatcc
     8581 attagatcct ggtgaagttt ttggcagtga aacattggtg cctatattaa atatattagg
     8641 ggaaatgggc ctagttaatt atcgtagtac aattcattta gaatttcgga cactaggagt
     8701 tactgtagga aatgtttata ctttttttag aagacccttg catgattttg gtctagttgg
     8761 tatgtatgtg tttgtctttg ctgtaggtgc tttttttgct atttattatt tagttctgag
     8821 aaagaaacag gttggtttta atttggatat tcataccatt atttattctt atgtctttta
     8881 ttggattttt ttatcatcaa tcgagcaata ctcgttcaca atgattagtc tatatacact
     8941 tgtatttatt gtgttggttt actttatggc tatcttttac tggtgtacag attttaaaag
     9001 aggaaaactg atttttaaaa tttctgactc aagtatcaaa ttaaaagaag aataacagaa
     9061 tgtataggag agggtagatg aatactaaaa ttaaaaatat aataactagt ttttcttatg
     9121 ttatttcttc aaatctgctc atagttttaa cctcatcact agttgttttg atttttccta
     9181 aaataatggg ggtaactgag tacagttact ggcaacttta tattttttat ctgacctata
     9241 tcggtttttt ccacttgggt tggattgatg ggatttatct caaatatggt ggcttagaat
     9301 atacaaattt agatagaaaa cagttttatt ctcagatgat tctattttct agtttcttaa
     9361 tgctaatctc gctggtatta tttactttga acctaataac tgtaagggat gaaaacgcaa
     9421 gatatattta taatatggct atcattagca tgatagtcac aaacttaaga acactctatg
     9481 tttatatctt gcagatgaca aatcgcttga aggatagttc agtcattcta attagtgatc
     9541 gcgttttata tgtactcctt ttattcatgt ttattgtatt tggatggcat gagtacaagg
     9601 tcatgatttg ggctgatatt ctaggtcgaa cattttctct catgctttcc ttctggattt
     9661 gtaaagatat tgtgtttcag cctttgtcaa aatttatctt agatttcaag gagtcccttg
     9721 ataatatccg tgttggaatc aatttaatgc tatctaacat tgcgagtagc atgattatag
     9781 gcattgttcg tatgggaatt caatggaatt ggaatattga aacattcggg aaagtgtcat
     9841 taactttgag tatatctaat ttattaatga cttttattaa tgccattgga ttagttatct
     9901 ttcctttgat aaagcgaaca aagactgaga atttacctaa aatttattct aatttaagaa
     9961 atgctttgat gttggttatg ttcgcaatct tgctcttcta ctatccttta aaatttattc
    10021 ttgatatttg gcttcctgct tataaggatg ccttagtttt catggcccta atttttccta
    10081 tgtcagttta tgaagggaaa atggctttgg tgataaatac atatttaaaa gcaatgagaa
    10141 tggaaaaaga cattctcaaa attaatgctt tggttatgtt aactagtatg gtagtgacat
    10201 tagtgactac tctactacta aataatttgg ggctgacagt tgtatctata gttattttac
    10261 ttgctttaag aagtataata gctgaattaa ttttatccaa aaaactgaag atatcagtca
    10321 agcaagacat tgctttagag ttacttatga cgattatatt tatttcttca agttggtatc
    10381 tctctatttg gattgcagta ataatttatt tattggcgta tactttatat ttgtatttaa
    10441 agcacaaaga tatcagaatg tatatagaat actttaaaaa tcataaaaaa atatcataaa
    10501 aattatatat caatgaaatg gtagattaca tttctacctt tttatccatt taggaggaaa
    10561 cgatgaaaaa gataatgcta gttttcggta cacgtccaga agcaataaaa atgtgttcat
    10621 tagtcaatga gttgagaaaa caggaagata tgaaaacagt tgtttgtgta actggtcaac
    10681 acaaggagat ggttagccct gttttagatt tatttggagt tcaaccagac tatgatttag
    10741 aaattatgaa ggctaatcaa aacttgttct ctataacaat aagtatttta gaaaaaataa
    10801 aacctgtgtt agaaaaagaa caaccagata ttgttttggt tcacggtgat actactacga
    10861 catatgcagc agctttagcg gcattttatc taggaattaa agttggtcat gttgaagctg
    10921 gattacgaac ttacaacctg caaagtcctt tcccagaaga gttcaacaga caatcgactt
    10981 ctattattgc aaattatcat tttgctccta cagaattagc taaagaaaat ctaataaaag
    11041 agggtagaaa taatatctat gttactggaa atacagtgat tgatgcactt acaactacag
    11101 tacaaaagga ttatacacac cccgatctag atttaaacga tggaaatcgc ctcatcttat
    11161 tgactgctca tagacgcgaa aatctcggag aacctatgag acatatgttt agagctgtta
    11221 aacgagtttt aaatgaatat gacgatgtta aagtaattta tccaattcat aaaaatccat
    11281 tggtacggga aacagctaca gaaatttttg gagatacaga acgtattcag atcattgaac
    11341 ctttagatgt tcttgatttt cacaacttta tgaatcatag ttatatgatt ctaactgact
    11401 caggaggggt tcaagaagag gcaccttcgt taggaaagcc tgtattggtc atgcgagata
    11461 cgacagaaag acctgaagga gtagctgctg gaacgttgaa attggttggg actgatgagg
    11521 agactattta tcaaaacttt aagatgcttt tagacgatcc cgaagaatat aaaaaaatga
    11581 gtcaagctag taatccttat ggaaatggtg atgctagtaa acagattgtt cgaattttac
    11641 gtggaatttg agtgtgttca gataaagtaa tatagaaagg taccctacta tgaaaggtat
    11701 tattctagca ggtggttcgg ggacacgttt atatcctttg actcgcgctg catcaaaaca
    11761 acttatgccg gtttatgata aaccgatgat ttactaccca ctttcaacat tgatgttggc
    11821 tgggattagg gatattttga ttatttccac tccacaggat ttacatcgat tccaagagct
    11881 tcttcaagac ggatctgagt ttgggctcaa actttcttat gcagagcaac caagtccaga
    11941 tggtttggca caagccttta tcattgggga agagtttatt tctgatgata gcgttgcgct
    12001 gatcttaggt gacaatatct atcacggttc tgggctttcc aagatgctac aaaaggcagc
    12061 gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc aaggatccag agcgctttgg
    12121 tgtggttgag tttgatcagg atatgaaggc tatttctatt gaagaaaagc cagagcaacc
    12181 tcgttcaaac tatgcagtta caggtctcta tttctatgat aatgatgtag tagagattgc
    12241 caagagtatt aaaccaagtc ctcgtggtga actggaaatt acagatgtaa acaaggctta
    12301 cctagatcgt ggtgatttgt ctgttgagct tatgggacgt ggctttgctt ggctggatac
    12361 tggaactcat gaaagtttac tagaggcttc acagtacatc gaaacagtgc aacggatgca
    12421 aaatgttcag gtagcaaact tagaagaaat tgcttaccgt atgggctata tcagtcgaga
    12481 agatgtattg gccttagccc aaccacttaa gaaaaatgaa tacggacagt atctgctccg
    12541 tttgattgga gaagcataga tgacagataa ttttttcggt aagacgcttg cggcacgcaa
    12601 ggttgaagct attccaggca tgttggagtt tgatatcccc gttcatggag ataaccgtgg
    12661 ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca cttggatttc cagagtcttt
    12721 ctttgcagaa ggaaaattgc aaaacaatgt atccttctca cgtaaaaatg tccttcgagg
    12781 tctccacgca gagccttggg ataagtacat ctctgtagca gatggaggga aagttctggg
    12841 ttcttgggtt gatctacgcg agggtgaaac ctttgggaat acctatcaga cagtgattga
    12901 tgcgagtaag ggaatctttg ttcctcgagg cgtagctaat ggctttcaag ttttatcaga
    12961 tacagtgtca tatagctatc tggtcaatga ttactgggct cttgaactca aacccaagta
    13021 tgcctttgtg aactacgctg atccaagcct tggtattgaa tgggaaaata ttgcagaagc
    13081 agaggtttca gaagcagaca aacatcatcc actacttaag gatgtaaaac ctttgaaaaa
    13141 agaagatttg gaataaggaa agaatatgac tgaatacaaa aatattatcg tgacaggtgg
    13201 agctggcttt atcggttcta actttgtcca ttatgtttac gagaactttc cagatgttca
    13261 tgtgacagtc ctagataagt tgacttatgc tggaaaccgc gcgaatattg aggaaatttt
    13321 aggtaatcgt gttgagttag ttgttggtga cattgctgat gcggagttgg tagacaagtt
    13381 ggctgctcaa gcagatgcta tcgttcatta tgcagcggaa agccacaatg ataattcgct
    13441 caatgatcca tcgccattta ttcatactaa cttcatcgga acctatactc ttttagaagc
    13501 tgctcgtaag tatgatattc gcttccacca tgtatcgaca gatgaagttt atggggatct
    13561 ccctttacgc gaagatttgc caggtcatgg tgaaggacca ggtgagaaat ttactgctga
    13621 aacaaaatac aacccaagct ctccgtactc atcaaccaag gcagcctcag atttgattgt
    13681 caaagcctgg gtgcgttctt ttggagtcaa ggcaacgatt tccaactgtt caaataacta
    13741 cggtccttat caacatatcg aaaaattcat cccacgtcag attactaaca tcctaagtgg
    13801 tatcaagcca aaactttacg gtgaaggtaa gaacgttcgt gattggattc ataccaatga
    13861 ccattcttca ggagtttgga caatcttgac aaaagggcaa atcggtgaaa cctacttgat
    13921 tggggctgat ggtgagaaga acaataagga agttttggaa cttatcctta aggaaatggg
    13981 acaagctgcg gatgcctatg atcatgtgac tgaccgtgca ggacatgacc ttcgctatgc
    14041 gattgatgct agcaagctcc gtgatgagtt ggggtggaaa cctgaattta ccaactttga
    14101 agctgggctc aaggcaacaa tcaagtggta tacagataac caagaatggt ggaaagcaga
    14161 gaaagaagct gttgaagcca attatgctaa gactcaggag attattacag tataaaaagc
    14221 aggaaatagc tgctttttat tgctatattg ggaagagtta catattagaa aggtctagag
    14281 atgattttaa ttacaggggc aaatggccaa ttaggaacgg aacttcgcta tttattggat
    14341 gaacgtaatg aagaatacgt ggcagtagat gtggctgaga tggacattac cgatgcagaa
    14401 atggttgaga aagtttttga agaggtgaaa ccgactttag tctaccactg tgcagcctac
    14461 accgctgttg atgcagcaga ggatgaagga aaagagttgg acttcgccat caatgtgacg
    14521 gggacaaaaa atgtcgcaag agcatctgaa aagcatggtg caactctagt ttatatttct
    14581 acggactatg tctttgacgg taagaaacca gttggacaag agtgggaagt tgatgaccga
    14641 ccagatccac agacagaata tggacgcact aagcgtatgg gggaagagtt agttgagaag
    14701 catgtgtcta atttctatat tatccgtact gcctgggtat ttggaaatta tggcaaaaac
    14761 ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga ctttaacagt tgtaaatgac
    14821 cagtacggtc gtccgacttg gactcgtacc ttggctgagt tcatgaccta cctagctgaa
    14881 aatcgtaagg aatttggtta ttatcatttg tcaaatgatg cgacagaaga cacaacatgg
    14941 tatgattttg cagttgaaat tttgaaagat acagatgtcg aagtcaagcc agtagattcc
    15001 agtcaatttc cagccaaagc taaacgtccg ctaaactcaa cgatgagcct ggccaaagcc
    15061 aaagctactg gatttgttat tccaacttgg caagatgcat tgcaagaatt ttacaaacaa
    15121 gaagtgagat aagtagtaga atgattttct agtctaataa aagaggcaga taatgaactc
    15181 caaaggagct taagatgtac gattatcttg ttgttggtgc tggtctcttt ggcgcatagc
    15241 tttggctcag tttctattat cgctcacacc atccatcaga agtttaatct gaaggtaccc
    15301 aattatcgcc aagaagaaga ttgggctagg atgggtttac caatcacacg taaggaaatc
    15361 tctaattggc atatcaaggc aagtcaatac tatttagagt ccctttataa ccttttacga
    15421 gaaaagttgt tagaacaacc tcttcttcat gcggatgaaa cctcttatcg ggtcttagaa
    15481 agtgatagtc agctgaccta ctattggacc tttttgtctg ggaaagctga gaatcaagta
    15541 atcacgcttt accaccatga tcagtgtcgg agtggttcgg tagtgcaaga attcctagga
    15601 gattattctg gctatgtgca ttgtgatatg ttgcggcagt aacttaggac tttagtcctc
    15661 tagttctgtc tatgcgatag cagtccaagg tttaggagca aggcgacgct aagcttggta
    15721 aactgcgaac cgctagaagc ttatcgtcaa ctggaagaag ctgaacttgt tggatgttgg
    15781 gcgcatgtga gaaggaaatt ttttgaagtg ccccccaagc aagcagataa atcatcctta
    15841 ggagctaaag gtttagctta ttgtgatcag ttattttcct tggaaagaga ctgggaggct
    15901 ttgccagctg atgaacgact acagaaacgt caagaacatc tccaacccct aatggaagac
    15961 ttctttgctt agtgccgtcg tcagtcagtt ttatcgggtt caaaactagg aagggcaatt
    16021 gaatacagcc tcaagtatga agaaaccttt aagaccattt taaaagacgg acatctggtc
    16081 ctttccaata atctagctga acgcgccatt aaatcattgg ttatgggacg gagtaaaaga
    16141 gtccagtgga ctcttttagc ctaagctaaa ttttaaaaag cgagggtggt tattttctca
    16201 aagttttgaa ggagctaaag caagagctat tattatgagc ttattggaaa cagctaaacg
    16261 tcatcaacta aatagtgaga aatatctatc ctatcttcta gaatgtcttc caaacgagga
    16321 aactctcgta aacaaagagg ttttagaggc ctatttacca tggactaaag ttgtacaaga
    16381 aaagtgcaaa taagaaatct ccagattagg aactatccgt gagttcacta atctggagat
    16441 ttttcaatag acttcgttat tgggcggtta cgatatgatc actgacttcg tcagtcttat
    16501 ctacaacctc aaaactgtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga
    16561 ttttcattga gtattagaac agaaaaaata cttggagtat ttgtttgtgt gtttattttt
    16621 atataacaaa ctataaacaa aacaaaaata taaaaaaaga gacaaaaaaa gaacagaaag
    16681 caattgacaa cggtttcata tagtgttata cttatggcat aaagttaatg gaaagaaggg
    16741 aaaaacttat ggtattagat tatttctttg acaaaaacct tgtgttttgc ttagaagcgg
    16801 ataatcaaga acaactcttt gatcaggttg caactttatt ggaagaacga gaaattgtca
    16861 ctccaactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact ggtttagata
    16921 tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcatacagat attgttcata
    16981 atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt cacaatatga
    17041 tagctcctga taaggaagta gaagtatccc tactcttctt tattattaac aattcaagtt
    17101 caagtcaaac aaatattctg gctcagttga tggacttttt cacaggaaat ggacatcttg
    17161 aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttacattgct gaagcaaccg
    17221 cttaatcttg tctattaaaa aataaaatcg gaggaaatcc aaatgattaa aattcttgct
    17281 gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga agaagaactt
    17341 tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt aaacgaagac
    17401 cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg ttttgaacca
    17461 ggtatcccag ttatcgaagc tgggccaatc ttattccgta tcccagcaat gagcgctcca
    17521 gtatttgaca atattgaagc agctattaaa gaacacggat taagctaatt ctaatttgtt
    17581 aacattcata taacataaaa aagggaggaa ctgttatgga tgcaatcttt gacctaatcg
    17641 gaaaggtttt caatcccatt ttagaaatgg gtggacctgt catcatgtta atcattttga
    17701 cagtattggc tttacttttt ggagtgaaat tctccaaagc gcttgaaggt ggtatcaaac
    17761 ttgccatcgc tcttacaggt atcggtgcta tcatcggtat gctaaatggt gctttctcag
    17821 catcacttgc aaaattcgtt gaaaacactg gtatccaatt gagtattacc gacgttggtt
    17881 gggcaccact cgcaacaatc acttggggtt ctgcttggac actatacttc ttgctcatca
    17941 tgttgattgt caacatagtg atgctagcta tgaagaaaac agatacactt gacgttgata
    18001 tctttgatat ctggcacttg tctatcacag gtctcttgat taaatggtat gctgataaca
    18061 atggtgtgag tcaaggggtt tcactcttta ttgctacagc agctatcgtc cttgtcggtg
    18121 tgttgaaaat tatcaactct gacttgatga aacctacatt tgatgacctt cttaacgccc
    18181 caagttcatc accaatgaca tcaactcaca tgaactacat gatgaaccca gttatcatgg
    18241 ttttggataa gatttttgaa aaattcttcc caggccttga taaatatgac tttgatgctg
    18301 ctaaattgaa caagaaaatc ggtttctggg gatctaaatt cttcatcggt ttcatccttg
    18361 gtatcgttat cggtattatg ggaactccac atccaattgc aggtgttgca gatgcagata
    18421 aatggcgtct tgttatcaaa ggatggttgt ctcttggttt gactgccggt gtatctttgg
    18481 aactcttctc acttatcggt tcatggttca tcgcagccgt agaaccacta tcacaaggta
    18541 ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt caatatcggt cttgactggc
    18601 cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa cgtacttgca ccaatcatgt
    18661 tgattgaagc agtgcttctt tcaaaagttg gaaatggtat cttgccactt gcaggtatca
    18721 tcgctatggg tgttactcca gctctcttgg ttgtaactcg tggtaaattg ctccgtatga
    18781 ttatcttcgg aacactcttg ttgccactct tccttctttc aggtacactt attgcaccat
    18841 ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga aggtgtgagc caaactcaat
    18901 tgattactca ctctactctt gaaggaccaa tcgaaaaact tcttggttgg acaattggta
    18961 acactacaac tggtgatatc aaagcaatcc ttggtgcagt agtcttcctt gtattctata
    19021 tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg taacgaagag tacgcagcaa
    19081 aagcaaaata atgcgctcct ataaaatata aactcaatga aaatcaaaga gcaaactagg
    19141 aaactagcca caggttgctc aaaacacagt tttgaggttg tagataagac tgacgaagtc
    19201 agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa tcatatctac
    19261 ggcaaggcga cactgacgaa gtttgaattg gattttcgca gagtgtaaat tgttgaaact
    19321 aggttgtcat accatgtata ccacttgggc tttggcagta gctaactgca ctaaatataa
    19381 tataaggagg gttttatggg gaaaggccat tggaatcgga aaagagttta tagcattcgt
    19441 aagtttgctg tgggagcttg ctcagtaatg attgggactt gtgcagttct attaggagga
    19501 aatatagctg gagaatctgt agtttatgcg gatgaaacac ttattactca tactgctgag
    19561 aaacctaaag aggaaaaaat gatagtagaa gaaaaggctg ataaagcttt ggaaactaaa
    19621 aatgtagttg aaaggacaga acaaagtgaa cctagttcaa ctgaggctat tgcatctgag
    19681 aagaaagaag atgaagccgt aactccaaaa gaggaaaaag tgtctgctaa accggaagaa
    19741 aaagctccaa ggatagaatc acaagcttca agtcaagaaa aaccgctcaa ggaagatgct
    19801 aaagctgtaa caaatgaaga agtgaatcaa atgattgaaa acaggaaagt ggattttaat
    19861 caaaattggt actttaaact caatgcaaat tctaaggaag ccattaaacc tgatgcagac
    19921 gtatctacgt ggaaaaaatt agatttaccg tatgactgga gtatctttaa cgatttcgat
    19981 catgaatctc ctgcacaaaa tgaaggtgga cagctcaacg gtggggaagc ttggtatcgc
    20041 aagactttca aactagatga aaaagacctc aagaaaaatg ttcgccttac ttttgatggc
    20101 gtctacatgg attctcaagt ttatgtcaat ggtcagttag tggggcatta tccaaatggt
    20161 tataaccagt tctcatacga tatcaccaaa tacctttaca aagatggtcg tgagaatgtg
    20221 attgctgtcc atgcagtcaa caaacagcca agtagccgtt ggtattcagg aagtggtatc
    20281 tatcgtgatg tgactttaca agtgacagat aaggtgcatg ttgagaaaaa tgggacaact
    20341 attttaacac caaaacttga agaacaacaa catggcaagg ttgaaactca tgtgaccagc
    20401 aaaatcgtca atacggacga caaagaccat gaacttgtag ccgaatatca aatcgttgaa
    20461 cgaggtggtc atgctgtaac aggcttagtt cgtacagcga gtcgtacctt aaaagcacat
    20521 gaatcaacaa gcctagatgc gattttagaa gttgaaagac caaaactctg gaccgtttta
    20581 aatgacaaac ctgccttgta cgaattgatt acgcgtgttt accgtgacgg tcaattggtt
    20641 gatgctaaga aggatttgtt tggttaccgt tactatcact ggactccaaa tgaaggtttc
    20701 tctttgaatg gtgaacgtat taaattccat ggagtatcct tgcaccacga ccatggggcg
    20761 cttggagcag aagaaaacta taaagcagaa tatcgccgtc tcaaacaaat gaaggagatg
    20821 ggagttaact ccatccgtac aacccacaac cctgctagtg agcaaacctt gcaaatcgca
    20881 gcagaactag gtttactcgt tcaggaagag gcctttgata cttggtatgg tggcaagaaa
    20941 ccttatgact atggacgttt ctttgaaaaa gatgccactc acccagaagc tcgaaaaggt
    21001 gaaaaatggt ctgattttga cctacgtacc atggtcgaaa gaggcaaaaa caaccctgct
    21061 atcttcatgt ggtcaattgg taatgaaata ggtgaagcta atggtgatgc ccactcttta
    21121 gcaactgtta aacgtttggt caaggttatc aaggatgttg ataagactcg ctatgttacc
    21181 atgggagcag ataaattccg tttcggtaat ggtagcggag ggcatgagaa aattgctgat
    21241 gaactcgatg ctgttggatt taactattct gaagataatt acaaagccct tagagctaag
    21301 catccaaaat ggttgattta cggttcagaa acatcatcag caacccgtac acgaggaagt
    21361 tactatcgcc ctgaacgtga attgaaacat agcaatggac ctgagcgtaa ttatgaacag
    21421 tcagattatg gaaatgatcg tgtgggttgg gggaaaacag caaccgcttc atggactttt
    21481 gaccgtgaca acgctggcta tgctggacag tttatctgga caggtacgga ctatattggt
    21541 gaacctacac catggcacaa ccaaaatcaa actcccgtta agagctctta ctttggtatc
    21601 gtagatacag ccggcattcc aaaacatgac ttctatctct accaaagcca atgggtttct
    21661 gttaagaaga aaccgatggt acaccttctt cctcactgga actgggaaaa caaagaatta
    21721 gcatccaaag tagctgactc agaaggtaag attccagttc gtgcttattc gaatgcttct
    21781 agtgtagaat tgttcttgaa tggaaaatct cttggtctta agactttcaa taaaaaacaa
    21841 accagcgatg ggcggactta ccaagaaggt gcaaatgcta atgaacttta tcttgaatgg
    21901 aaagttgcct atcaaccagg taccttggaa gcaattgctc gtgatgaatc tggcaaggaa
    21961 attgctcgag ataagattac gactgctggt aagccagcgg cagttcgtct tattaaggaa
    22021 gatcatgcga ttgcagcaga tggaaaagac ttgacttaca tctactatga aattgttgac
    22081 agccagggga atgtggttcc aactgctaat aatctggttc gcttccaatt gcatggtcaa
    22141 ggtcaactgg tcggtgtaga taacggagaa caagccagcc gtgaacgcta taaggcgcaa
    22201 gcagatggtt cttggattcg taaagcattt aatggtaaag gtgttgccat tgtcaaatca
    22261 actgaacaag cagggaaatt cacccttact gcccactctg atctcttgaa atcgaaccaa
    22321 gtcactgtct ttactggtaa gaaagaagga caagagaaga ctgttttggg gacagaagtg
    22381 ccaaaagtac agaccattat tggagaggca cctgaaatgc ctaccactgt tccgtttgta
    22441 tacagtgatg gtagccgtgc agaacgtcct gtaacctggt ctcaagtcga tgttagtcaa
    22501 gcaggagttg tgactgttaa aggtacagca aatggacgtg aggtagaggc tcatgtcaag
    22561 gttctagcaa ttgcgaaaga attaccaaca gttaaacgta ttgctccaaa tactgacttg
    22621 aattctgtag acaaatctgt ttcttatgtt ttgactgatg gaagtgtaca agagtacgaa
    22681 gtagatagct gggagattac ggaagtagat aaagccaaac tttcagtagc tggatcacgt
    22741 attcaaatga ctggtcagtt agctggagaa actattcatg caacccttgt ggtagaagaa
    22801 ggaaatgctg cagcacctgt agtgccaact gttactgttg gaggtgaagc agtaacaggt
    22861 cttactagtc gacaaccaat gcaatatcgt actctatctt atggtgccca attgccagaa
    22921 gtcacagcaa gtgctgaaaa tgctgatgtg acagttcttc aagcaagcgc agcaaacggc
    22981 atgcgtgcga gcatctttat tcagcctaaa gatggtggcc ctcttcaaac ctatgcaatt
    23041 caattccttg aagaagcgcc aaaaattgct cacttgagct tgcaagtgga aaaagctgac
    23101 agtctcaaag aagaccaaac tgtcaaattg tcggttcgag ctcactatca agatggaacg
    23161 caagctgtat taccagctga taaagtaacc ttctctacaa gtggtgaagg ggaagtcgca
    23221 attcgtaaag gaatgcttga gttgcataag ccaggagcag tcactctgaa cgctgaatat
    23281 gagggagcta aagaccaagt tgaactcact atccaagcca atactgagaa gaagattgcg
    23341 caatccatcc gtcctgtaaa tgtagtgaca gatttgcatc aggaaccaag tcttccagca
    23401 acagtaacag ttgagtatga caaaggtttc cctaaaactc ataaagtcac ttggcaagct
    23461 attccgaaag aaaaactaga ctcctatcaa acatttgaag tactaggtaa agttgaagga
    23521 attgaccttg aagcgcgtgc aaaagtctct gtagaaggta tcgtttcagt tgaagaagtc
    23581 agtgtgacaa ctccaatcgc agaagcacca caattaccag aaagtgttcg gacatatgat
    23641 tcaaatggtc acgtttcatc agctaaggtt gcatgggatg cgattcgtat agagcaatac
    23701 gctaaggaag gtgtctttac agttaatggt cgcttagaag gtactcaatt aacaactaaa
    23761 cttcatgttc gcgtatctgc tcaaactgag caaggtgcaa acatttctga ccaatggacc
    23821 ggttcagaat tgccacttgc ctttgcttca gattcaaatc caagcgaccc agtttcaaat
    23881 gttaatgaca agctcatttc ctacaataac caaccagcca atcgttggac aaactggaat
    23941 cgtactaatc cagaagcttc agtcggtgtt ctgtttggag attcaggtat cttgagcaaa
    24001 cgctccgttg ataatctaag tgtcggattc cacgaagacc atggagttgg tgcaccgaag
    24061 tcttatgtga ttgagtatta tgttggtaag actgtcccaa cagctcctaa aaaccctagt
    24121 tttgttggta acgaggacca tgtctttaat gattctgcca actggaaacc agttactaat
    24181 ctaaaagccc ctgctcaact caaggctgga gaaatgaacc actttagctt tgataaagtt
    24241 gaaacctatg ctgttcgtat tcgcatggtg agagcagaca acaaactagg aacgtctatc
    24301 acagaggtac aaatctttgc gaaacaagtt gcggcagcca agcaaggaca aacaagaatc
    24361 caagttgacg gtaaagactt agcaaacttc aaccctgatc tgacagacta ctaccttgag
    24421 tctgtagatg gaaaagttcc ggcagtcaca gcaagtgtta gcaacaatgg tctcgctacc
    24481 gtcgttccaa gcgttcgtga aggtgagcca gttcgtgtca tcgcgaaagc tgaaaatggc
    24541 gacatcttag gagaataccg tctgcacttc actaaggata agaacttact ttctcataaa
    24601 ccagttgctg cggttaaaca agctcgcttg ctacaagtag gtcaagcact tgaattgccg
    24661 actaaggttc cagtttactt cacaggtaaa gacggctacg aaacaaaaga tttgtcagtt
    24721 gaatgggaag aagttccagc agaaaatctg acaaaagcag gtcaatttac cgttcgaggc
    24781 catgtccttg gtagtgatct tgttgctgag gtcactgtac gagtgacaga caaactaggc
    24841 gaagctcttt cagataaccc taactatgat gaaaacagta accaggcctt tgcttcagca
    24901 accaatgata ttgacaaaaa ctctcatgac cgcgttgact atctcaatga cggagatcat
    24961 tcagaaaatc gtcgttggac aaactggtct ccaacaccat cttctaatcc agaagtatca
    25021 gcgggtgtga tcttccgtga aaatggtaag attgtagaac ggactgttgc gcaagccaaa
    25081 cttcacttct ttgcagatag tggtacggat gcaccaacta aactcgtttt agaacgctat
    25141 gtcggtccag agtttgaagt gccaacctac tattcaaact accaagccta cgacgcagac
    25201 catccattca acaatccaga aaattgggaa gctgtgcctt atcgtgcgga taaagacatc
    25261 gcagctggtg atgaaatcaa cgtaacattt aaagctgtca aagccaaagc tatgagatgg
    25321 cgtatggagc gtaaagcaga taagagcggt gttgcgatga ttgagatgac cttccttgca
    25381 ccaagtgaat tgcctcaaga aagcacgcaa tcgaagattc ttgtagatgg aaaagaactt
    25441 gctgatttcg ctgaaaatcg tcaagactat caaattacct ataaaggtca acggccaaaa
    25501 gtctcagttg aagaaaacaa tcaagtagct tcaactgtgg tagatagtgg agaagatagc
    25561 cttccagtac ttgttcgcct cgtttcagaa agtggaaaac aagtcaagga ataccgtatc
    25621 cacttgacta aggaaaaacc agtttctgag aagacagttg ctgctgtaca agaagatctt
    25681 ccaaaactcg aatttgttga aaaagatttg gcctacaaga cagttgagaa aaaagattca
    25741 acactgtatc taggtgaaac tcgtgtagaa caagaaggaa aaactggtaa agaacgtatc
    25801 tttacagcga ttaatcctga tggaagtaag gaagaaaaac tccgtgaagt ggtagaagct
    25861 ccgacagacc gcatcgtctt ggttggaacc aaaccagtag ctcaagaagc taaaaaacca
    25921 caagtgtcag aaaaagcaga tacaaaacca attgattcaa gtgaagctag tcaaactaat
    25981 aaagcccagt taccaaatac aggtagtgcg gcaagccaag cagcagtagc agcaggttta
    26041 gctcttctag gtttgagtgc aggattagta gttactaaag gtaaaaaaga agactagaaa
    26101 ttttgatacc ttctttatca ttaaagacca aagaaaaact cttgtcctaa atagaagata
    26161 aagagtctgg aacaaaatag ttctcaacca caaaaaagct agatatttcc aattgcggaa
    26221 ctctagcttt ttaattttga gtcgttctct tattgtatag tagattgaaa ctagagtagt
    26281 acacttctac ttctaaaaca ttgttagaaa tcgatttgac tgtccttatc gatttgtcct
    26341 gttcttattt catttcacta tgttttagga ggttattggc cataagtacc aatcccatgt
    26401 caattctcac ttgacgcttg cctctcagat tacatctctt gtaacccaaa caagccttta
    26461 tctgcccaaa gacaggttcc acatcaatct tgcgttgggc gaaaatctgt ctatcttggg
    26521 gagataaaag cgcctgacat tctttagctt tcaagttttg atagcgttcg ttcatataca
    26581 gtcccttttg aggggctgat tcaggttcat cagcgtagta aaccttgatt tcctgttgaa
    26641 agtctgtctg tgttttctga tgtttggtat ggtgaaaacg ataataccag ccatcaggat
    26701 gtgtgtagct atcctccttg tcattatagt gccaattcgc taagttttta gctgactgtt
    26761 tataccctct cttttgttcc ttatcaaaca tggcatattt aatcagaagg ggagtgattt
    26821 cttcttgaaa atagacttgt atctgttctt gaagtttggc ggagaatttc tctgtcgttt
    26881 tcttccacac aaaactatac ttgttggcat tggcttcaat cttagttccg tcaataaaca
    26941 aacaatctaa ggtcactaac tcttccattt ttcaattttt cgaccagaga aaatcccttg
    27001 tgaataggca aatagaagag tagatacaag cattttaggg tgataagacg ggcgatcaaa
    27061 ggcatgatag aaggcgtgga aatgacaatc ctccaaggta ttcaccactt tttcaatagt
    27121 aaagacgaga tggtcttgtg gtaagaagga actgatttct agtggtaaag ttgtttgatt
    27181 tgtgttatag tgaatatgca tgggatagcc tttttaaatg gtttattaag caattctatt
    27241 ttactaaaac tatcgtaacc atgcaaaaaa gcaacggcaa atccgttgcc ttttttggat
    27301 ataagagact attgtcccag actcttttct ttgtataaaa ttgtatagtg ttattgtcta
    27361 tactattttg tagagaaagc aaaaatccct agaaaatgct tagggattcg actatttcat
    27421 taagaacaat tcaacaatca tttctatata catgataagg gttaataaga atcctgcacg
    27481 ccagaagaat ttgatgaatt taggatagta aaagctgcgt tttttcaaaa ggaagaaaaa
    27541 gacgagaata atggctagga acgagagggc tagccccagt ctagggagga aattatgggt
    27601 aaaggtttta gctgtaatca agtaatactc aaataccaag actggaaaag ccaaatccgc
    27661 aaagtttcgt cctagttttt ttaatctaaa aagtttggtt aggataatgc agacgactaa
    27721 ggtcagtatc aataataaaa tagatgctaa tttcattaaa atcataccca tattgtatca
    27781 taaaaaaagg ctaatggaaa cgagaaacag aggaatttat aggaaagtca ggcttttgag
    27841 attgtgggtg atttttgtta taatgaaagt tataaaatct tataatacct tgaatgatta
    27901 ttatcgaaaa ctctttggag aaaagacttt taaagtccct attgatgcgg gatttgactg
    27961 tcccaatcgt gatggaactg tggctcatgg aggctgtact ttttgtacgg tttccggttc
    28021 tggagatgcc attgtggcac cagatgcgcc tatccgtgag taattttata aggaaattga
    28081 ctttattcac cgtaagtggc cagatgttca gaagtatctg gtttattttc aaaattttac
    28141 caacacccgt gaaaaggtgg aagttattcg agagcgttat gaacaggcta tcaatgagcc
    28201 aggtgtggta ggaatcaata ttggaacgcg cccagactgt ttaccagacg aaaccatcga
    28261 atatttggct gagttatcgg agtgcatgca tgtgacggtt gaattgggct tgtagactac
    28321 ttatgaagca acttctgacc tgattaaccg tgcgtattct tatgaattgt aggtggaaac
    28381 ggtcaagcgt ttgagaaagt atcccaagat tgagattgtt tcccatttga tcaatggttt
    28441 gcctggtgaa acccatgaga tgatggttga aaatgtccgc cgttgtgtca cgaataacga
    28501 tattcaaggg attaaactgc atttgctcca tcttatgaca aatactcgta tgcaacgaga
    28561 ttaccatgag ggacgtttac aattgatgag tcaggacgaa tatgtcaggg tcatctgtga
    28621 ccaactggaa attattccca aacatatcgt catccatcga attacaggag atgcgcctag
    28681 ggatatgctg cttgggccta tgtggagcct caataaatgg gaagctctca acagcattga
    28741 gatggagatg cgacgtcgtg gaagtgttca aggatgcaag gctgtaaaac aggagtttga
    28801 aaatgaaaag accacttgag atggcacatg attttttggc tgaggtcgtg acaaaagagg
    28861 atgtcgtagt ggatgcgact atgggaaatg gtcatgacac gcttttttta gccaagctag
    28921 ccaagcaagt ctatgccttt gatattcaga agcaagcctt ggaaaagacc caagagcgtt
    28981 tgcatcaggc tgacttgaca aatgcccagt taatcttgca aggccatgag acactggacc
    29041 agtttgtgat aaaagctaag gcagggattt ttaatctggg ctatttgccg tcagctgata
    29101 agtctgtcat cacccgaccg cagacaacga ttgaggcatt agaaaagcta tgtggcttac
    29161 ttgtcaaagg tggacgaatt gctattatga tttactatgg tcatgaagga ggcgatctcg
    29221 agagagatgc tgtcttggat tttgtgatcc agttgaacca acaagagtac acagctgcca
    29281 tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt agtgatgatt gaaaaattag
    29341 agagatacag acatggataa acaataccta cacgaaaagc tggatgccat gcgccagaat
    29401 tttgttgaat caacccacca cgaacgagcg gtgggcgtgc tagaccaagc gcatatgagc
    29461 aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg aaatggaacg gtgccagaga
    29521 aaaattgagc acaaagactg ttccaagatt gaccaaaaaa tcaaagagca gaaggagata
    29581 tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt ggaattactg atttacctca
    29641 tcctattttt actggttttg attgtctcaa gtacaaccaa taagctcctg ccctttttgc
    29701 ctctcccttt ggtgcagatt cttttgggaa ttgtgattgg tctcttttta cccaatactg
    29761 actttcacct taatacggag ttgtttttgg cactggttat cggacccttg cttttccgag
    29821 aggctgaaga agcagatgtt acggctattt taaaacactg gcgaatcatt gtttatctca
    29881 tatttccagt gatttttatc tcgaccctga gtttgggtgg cttggcccat cttctttggt
    29941 tcagccttcc cttggcagct tgcttggctg ttggtgcagc ccttggtcct acggacttgg
    30001 tggcctttgc ctctctttcg gagcgtttta gctttcctaa gcgcgtgtcc aatattctta
    30061 agggcgaagg actcttgaat gatgcttctg gtttggtggc ttttcaggta gctttgacag
    30121 cttggacaac tggagctttt tctctggggc aagctagcag ttcgctcatc ttttcaatcc
    30181 taggcggttt tttaattgga tttttaacag ccatgaccaa ccgcttcctc cataccttct
    30241 tgctaagtgt gcgcgcaacg gatattgcca gtgaactttt attagaattg agtttgcctc
    30301 tagtgacctt ctttctggca gaagaagtcc atgtttcagg gattattgcc gtcgtagttg
    30361 ctggaatttt aaaggcaagt cgcttcaaga aaatcacgct cctcgaagcc caagtggata
    30421 cggtgaccga gacggtctgg catacagtga cctttatgct caacggttct gtctttgtga
    30481 ttttagggat ggagttggaa atgatagcag aacctatctt gaccaatcca atctataatc
    30541 ctctactttt attgctatct ctcatcgccc ttacctttgt cctctttgtc attcgtttta
    30601 ttatgatcta tggctattat gcctatagaa cccgacgcct caagaaaaag ctaaataagt
    30661 atatgaagga catgtttctc ttgacctttt caggtgttaa gggaacggtg tcgattgcta
    30721 cgattctctt gataccaagt aatctagaac aggagtatcc tctcttgctt ttccttgttg
    30781 caggtgtgac gcttgtcagc tttttaacag gtctcttggt cttgcctcat ctttctgatg
    30841 aagaggaaga aagcaaggat tatctcatgc atatcgccat tttgaatgaa gtaacgctag
    30901 agttggaaaa agagttggaa gacaccagaa ataaacttcc cctctatgcg gctattgaca
    30961 attatcatgg acgtattgaa aatctcattt taagccaaga aaaccaggat gatcaagaag
    31021 attgggctgc tttgaaactc ttgattctta gtattgaaag tgatggtttg gagcaggcct
    31081 atgaagaggg gaacattagc aatcgtgctt accgagttta ccaacgttat ctgaaaaata
    31141 tagaacaagg aatcaatcgt aaacttgcct caagactgac ctattatttc cttgtttctt
    31201 tgcggatttt acgttttctc cttcatgaag tttttactct cggaaagacc ttccgtagct
    31261 ggaagaacaa ggagcaaagc cgtctccgtg ctcttgatta tgaccaaatt gcagagctct
    31321 atcttgccaa tacagagatg attattgaaa gtttggaaaa cctgaaggga gtctacagac
    31381 gctctttgat tagttttatg caggagtctc gtcttcgaga aacagctatt atcagcagtg
    31441 gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa caatatcgat gaaatgctga
    31501 gaggctatta tctggagcgc aagttgattt tcgaatacga agaaaaacga ttgattacga
    31561 ctaagtatgc caagaaatta cgacaaaatg taaataactt agagaactat tccttgaagg
    31621 aagctgccaa taccctaccg tatgatatgg tggaattggt aagaagaaat tagttaatac
    31681 tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtatg tgactgactt
    31741 cgtcagtctt atctacaacc tcaaaacagt gttttgagca gcttgcggct agctttctag
    31801 tttgctcttt gattttcatt gagtataaga ttataaatga aggagtatga catgaaaaag
    31861 tggtggaaag agctgataga caagccttta ttaaaagctt ttttgcatta ttatcaagca
    31921 tcagatagtg agttgaccag tgtcgcagta gcctactatt ggttgatttc gattttcccc
    31981 ctgcttttgg tggtggtcaa tatcctcccc tattttcaga ttcctgtggg agaatttttg
    32041 ggctttatga aagacgtcct gcccccaagc ctctatgaag gtgtggaaaa aatagccaga
    32101 gaagtcttga cgcaaccttc aacaggttta ttgagttttt ctgttttatc ggcgttatgg
    32161 agtttttcaa aatctatgaa tttcttgcaa aaagctttta acaaggctta tggcgtcgaa
    32221 aagagtcgtg gacttatttc ccatcagatg ctaagtctcc tagtcagttt tggcttgcag
    32281 ctcctctttg cgtttgcctt gtttttgatc ttatttggtc agatgatttt ggctttactt
    32341 gctcattatt ggacaaaaga tggcattatc tatcaggctt tacaagggtt ggcaggtcct
    32401 ctgatttacg ccctcctctt tgctatcttg gtcatgcttt attattttct tcccaatcta
    32461 tctaacagga aaattagcta taccctacca ggcagtgcct ttgttctctt agtgatttta
    32521 ggtttactaa ctctgttctc tagttatctc aattactatg tccatcattt ggtggatgtc
    32581 cgaattttag gttccgttct tcttgttgtt atgatgtttt ggtttatctt gattgctaaa
    32641 attgttatcc taggcgcggt gatcaatgcc agtatgcaga gtttgaaaga tccggtcttt
    32701 aaaaaagact aactatttat ccattacaaa agcgcatagt atcaaggctt tatagaatct
    32761 tgatactatg cgcttttgtg ctttgacagt tttttgtata gtttttgtcc aagatttcta
    32821 aatcatctga ttaaattcct attttcccct atcattgtcc ctgttttttc gaaaatggaa
    32881 ggagtataat aaatctatca ataaaatgat aggaggaact ttatgggtca tattttcttt
    32941 tttctaagtg tctttttggc agggattcta tccttctttt ctccttgtat cttacctttg
    33001 ttaccggtct atacaggagt gttactagat gataaggatg gtgctcaggc ttctagcggc
    33061 aaattttcaa tctcagttac tagtttatta cgaactctgg cctttatagc aggaatttcc
    33121 tttatattta ttttgttggg ctatggagct ggttttttag gcgatttgct ttatgcttct
    33181 tggttccaat atcttactgg ggcaattatt atccttcttg gtttgcacca aatggagatt
    33241 ctacacttta aggggcttta taaggaaaag aggctacaac tgcaaggaca ggggcaaaat
    33301 ggtaagggct atagtcaggc atttttattg ggcttgacct ttagttttgc ttggacgcct
    33361 tgcgtggggc cggttctggg gtctgttttg gccttggcgg cttcaggtgg ttcaggagct
    33421 tggcagggag ctggtctcat gttggtgtat acgctgggct tggcgctacc attcttgctt
    33481 ctagctctga cctctagtta tgttttgaaa catttccgaa aacttcatcc ctatctcgga
    33541 atcctcaaaa aagtgggtgg ttttctcatt attgtgatgg gattcttggt tctgtttgga
    33601 aatgcttcaa ttttaagtca attatttgaa taaaatggaa aggaatatca atatgaaaaa
    33661 atggcaaaca tgtgttcttg gagcaggttc gctcctttgt ttgacggctt gttcaggcaa
    33721 gtccgtgact agtgaacacc aaacgaaaga tgaaatgaag acggagcaga cagctagtaa
    33781 aacaagcgca gctaaaggga aagaggtggc tgattttgaa ttgatgggag tagatggcaa
    33841 gacctaccgt ttatctgatt acaagggcaa gaaagtctat ctcaaattct gggcttcttg
    33901 gtgttctatc tgtctggcta gtcttccaga tacggatgaa attgctaaag aagctggtga
    33961 tgactatgtg gtcttgacag tagtgtcacc aggacataag ggagagcaat ctgaagcgga
    34021 ctttaagaat tggtataagg gattggatta taaaaatctc ccagtcctag ttgacccatc
    34081 aggcaaactt ttggaaactt atggtgtccg ttcttaccca acccaagcct ttatagacaa
    34141 agaaggcaag ctggtcaaaa cacatccagg attcatggaa aaagatgcaa ttttgcaaac
    34201 tttgaaggaa ttagcctagg aggtgtctta tgaatgataa gttaaaaatc ttcttgttgc
    34261 taggagtatt ttttctagcc ataaccggtt tctatgttct attgatacga aatgcagggc
    34321 agacagatgc ctcgcaaatt gaaaaggcgg cagttagcca aggaggaaaa gcagtgaaaa
    34381 aaacagaaat tagtaaagac gcagacttgc acgaaattta tctagctgga ggttgtttct
    34441 ggggagtgga ggaatatttc tcacgcgttc ccggggtgac ggatgccgtt tcaggctatg
    34501 caaatggtag aggagaaaca accaagtacg aattgattaa ccaaacaggt catgcagaaa
    34561 ccgtccatgt cacctatgat gccaagcaaa tttctctcaa ggaaatcctg cttcactatt
    34621 tccgcattat caatccaacc agcaaaaata aacaaggaaa tgatgtgggg acccagtacc
    34681 gtactggtgt ttattacaca gatgacaagg atttggaagt gattaaccaa gtctttgatg
    34741 aggtggctaa gaaatacgat caacctctag cagttgaaaa ggaaaacttg aagaattttg
    34801 tggtggctga ggattaccat caagactatc tcaagaaaaa tccaaatggc tactgccata
    34861 tcaatgttaa tcaggcggcc tatcctgtca ttgatgccag caaatatcca aaaccaagtg
    34921 atgaggaatt gaaaaagacc ctgtcacctg aggagtatgc agttacccag gaaaatcaaa
    34981 cagaacgagc tttctcaaac cgttactggg ataaatttga atccggtatc tatgtggata
    35041 tagcaactgg ggaacctctc ttttcatcaa aagacaaatt tgagtctggt tgtggctggc
    35101 ctagttttac ccaacccatc agtccagatg ttgtcaccta caaggaagat aagtcctaca
    35161 atatgacgcg tatggaagtg cggagccgag taggagattc tcaccttggg catgtcttta
    35221 cggatggtcc acaggacaag ggcggcttac gttactgtat caatagcctc tctatccgct
    35281 ttattcccaa agaccaaatg gaagaaaaag gctacgctta tttactagat tatgttgatt
    35341 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat gtagggttac
    35401 tgacttcgtc agttttatct acaacctcaa agctatactt tgagttgact tcgtcagttt
    35461 tatttacaac ctcaaagcta tactttgaga aacctgtggc tatcttccta gtttactttt
    35521 tgatttttat tgagtataag aggtctttcc taagcagtta gaggagaatt ttgctatact
    35581 gatactagta agtgacaaag gagagaagca tgacctacac aatcttaatc gtagaagatg
    35641 aatatctggt aagacaaggt ttgactaaac tggtcaatgt agcagcctac gatatggaaa
    35701 tcatcggtca ggctgaaaat ggaaggcagg cttgggaatt gatccaaaag caggtgccag
    35761 atatcatttt aaccgatatc aacatgcctc atctaaatgg catccagttg gccagtctgg
    35821 tacgagaaac ctatcctcag gttcatttgg tctttttaac aggttacgat gattttgatt
    35881 atgccttgtc tgctgtcaaa ctaggtgtgg acgactacct gctcaaaccc ttttctcgtc
    35941 aggatattga ggaaatgttg gggaaaatca aacaaaaact agacaaggaa gagaaagaag
    36001 agcagttaca agatttattg actaataggt ttgaaggaaa catggcccag aaaatccagt
    36061 ctcatctggc tgatagccaa tttagtttaa agtctttagc cagtgactta ggttttagtc
    36121 cgacctatct gagttccttg attaagaaag agttgggctt gccttttcag gattatctgg
    36181 tgagagaacg tgttaaacaa gccaagctct tgcttttaac tacagatctg aagatttatg
    36241 agatcgcaga gaaggttggt tttgaagata tgaactattt tacccaacgt tttaagcaga
    36301 ttgcaggtgt gacacctcgt cagtttaaga agggagaaga ccgatgaagc gttcttctct
    36361 tttagttaga atggttattt ccatctttct ggtctttctc attctcctag ctctggttgg
    36421 aactttctac tatcaatcaa gttcttcagc cattgaggcc accattgagg gcaacagcca
    36481 aacgaccatc agccagacta gccactttat tcagtcttat atcaaaaaac tagaaaccac
    36541 ctcgactggt ttgacccagc agacggatgt tctggcctat gctgagaatc ccagtcaaga
    36601 caaggtcgag ggaatccgag atttgttttt gaccatcttg aagtcagata aggacttgaa
    36661 aactgttgtg ctggtgacca aatctggtca ggtcatttct acagatgaca gtgtgcagat
    36721 gaaaacttcc tctgatatga tggctgagga ttggtaccaa aaggctattc atcagggagc
    36781 tatgcctgtt ttgactccag ctcgtaaatc agatagtcag tgggtcattt ctgtcactca
    36841 agaacttgtt gatgcaaagg gagccaatct tggtgtgctt cgtttggata tttcttatga
    36901 aactctggaa gcctatctca atcaactcca gttggggcag cagggctttg ccttcattat
    36961 caatgaaaac catgaatttg tctaccatcc tcaacacaca gtttatagtt cgtctagcaa
    37021 aatggaggct atgaaaccct acatcgagac aggtcagggt tatactcctg gtcacaaatc
    37081 ctacgtcagt caagagaaga ttgcaggaac tgattggacg gtacttggcg tgtcatcatt
    37141 ggaaaagtta gaccaggttc ggagtcagct cttgtggacc ttgcttgggg ccagtatcac
    37201 atctcttctt gtctgtctct gcttagtgtg gttcagtctt aaacgctgga ttgctccttt
    37261 gaaggatttg agagaaacca tgttggaaat tgcttctggt gctcaaaatc ttcgtgccaa
    37321 ggaagttggt gcctatgaac tgagagaagt aactcgccaa tttaatgcca tgttggatca
    37381 gattgatcag ttgatggtag ctattcgtag ccaggaagaa acgacccgtc agtaccaact
    37441 tcaagccctt tcgagccaga ttaatccaca tttcctctat aacactttgg acaccatcat
    37501 ctggatggct gaatttcatg atagtcagcg agtggtgcag gtgaccaagt ccttggcaac
    37561 ctatttccgc ttggcgctca atcaaggcaa ggacttgatt tgtctctctg acgaaatcaa
    37621 tcatgtccgc cagtatctct ttatccagaa acaacgctat ggagataagc tggaatacga
    37681 aattaatgaa aatgttgcct ttgataattt agtcttaccc aagctggtcc tacaacccct
    37741 tgtagaaaat gctctttacc atggcattaa ggaaaaggaa ggtcagggcc atattaaact
    37801 ttctgtccag aaacaggatt cgggattggt catccgtatt gaggatgatg gcgttggctt
    37861 ccaagatgct ggtgatagta gtcaaagtca actcaaacgt gggggagttg gtcttcaaaa
    37921 tgtcgatcaa cggctcaaac ttcattttgg agccaattac cagatgaaga ttgattctag
    37981 accccaaaaa ggaacgaaag ttgaaatata tataaataga atagaaacta gctaactccc
    38041 agtcaattct gggagtttta tgcgtaattg ggcaaacttt ctaggttgtc tatcttgcta
    38101 aaaacaagaa aaaacggtat gatagaagag tgacaacaga ggtaacagag atgaacgaga
    38161 cacagattca aagagaaaca cgtcaggtag tggaagatgt tttagaaaag accaatttga
    38221 aacagggggc cctttttgtt ttaggtctat cttctagtga ggtgctaggt ggtcagattg
    38281 ggaaagaatc cagtcaagag attggtgagc tgatagtgga gactatcttg ggtattctag
    38341 gtagtagagg tatccattta gcagttcaag gttgtgagca tgtcaatcgg gctctcgttg
    38401 ttgaacgtca ggtggcagag cagtttggtc tggaaattgt cagtgtccat cctactcttc
    38461 atgcaggagg ttcggggcag ttggcagcct ttaagtttat gcaggatcca gttgaggttg
    38521 aatttatcaa ggctcatgct ggattggata tcggagacac tgcaattggc atgcatgtca
    38581 agcatgttca ggttccgatt cgccctattt tgagagagat tggtcatgcc catgtaacgg
    38641 cactgactag tcgtccaaaa ttaatcggag gtgcgcgtgc gcactatccg caagatgcta
    38701 ttaggaagtt ttgagaatga ataaaggaga taaaagtgtt taaaaaagac cgtttttcaa
    38761 ttcgtaagat taagggagtt gtaggctctg tatttcttgg aagccttttg atggctcctt
    38821 ctgtagtgga cgcagccacc tatcactatg taaataaaga gattatttca caagaagcta
    38881 aagatttaat tcagacagga aagcctgaca ggaatgaagt tgtatatggt ttggtgtatc
    38941 aaaaagatca gttgcctcaa acagggacag aagcatctgt tttgacagct tttggtttgc
    39001 tgactgttgg gagcttgctt ttaatctaca agagaaagaa aattgctagc gtctttctag
    39061 ttggagctat gggattggta gttcttccta gtgcagaggc tgtagaccca gttgcgaccc
    39121 tagcgctggc tagtcgagag ggtgttgttg aaatggatgg ctatcgctat gttggttatc
    39181 tatcaggtga catcctcaaa acgcttggct tggacactgt tttagaagaa acctcagcaa
    39241 aacctggaga ggtgactgta gtcgaagttg agactcctca atcaacaaca aatcaggagc
    39301 aagctaggac agaaaaccaa gtagtagaga cagaggaagc tccaaaagaa gaagcaccta
    39361 aaacagaaga aagtccaaag gaagaaccaa aatcggaggt aaaacctact gacgacaccc
    39421 ttcctaaagt agaagagggg aaagaagatt cagcagaacc agctccagtt gaagaagtag
    39481 gtggagaagt tgagtcaaaa tcagaggaaa aagtagcagt taagccagaa agtcaaccat
    39541 cagacaaacc agctgaggaa tcaaaagttg aacaagcagg tgaaccagtc gcgccaagag
    39601 aagacgaaaa ggcaccagtc gagccagaaa agcaaccaga agctcctgaa gaagagaagg
    39661 ctgtagagga aacaccgaaa caagaagata cacagccaga agtagtagaa acaaaagatg
    39721 aggctgctaa tcaacctgtt gaagaaccaa aagttgaaac gcctgctgta gaaaaacaaa
    39781 cggaaccaac agaggaacca aaagttgaac aagtaggtga accagtcgag ccaagagaag
    39841 acgaaaaggc accagtctct ccagaaaagc aaccagaagc tcctgaagaa gagaagactg
    39901 cggaagaaac accgaaacaa gaagataaaa taaagggtat tggtactaaa gaaccagttg
    39961 ataaaagtga gttaaataat caaattgata aagctagttc agtttctcct actgattatt
    40021 ctacagcaag ttacaatgct cttggacctg ttttagaaac tgcaaaaggt gtctatgctt
    40081 cagagcctgt aaaacagcct gaggtaaata gcgagacaaa agctgaaaaa gttgcagcta
    40141 atacagatgc taaacaaagt gaagtaaatt ctgagactgc aagtcttaaa acagcaattt
    40201 ctggattaaa tacagataaa gttgaactcg aaaatcaact taagattgca cagggaaaaa
    40261 ctgaaactga tttcagcatg gaatcttgga cggttttgag tacagctaaa aataaagctc
    40321 aggaagtaaa agataacgga acagcgaccc aagaacaaat aaacgaagca gagaaaagtt
    40381 tgaaaacagc ccttgctgac ttatctgttg acaaaacagc tttgggaagc gctatcgata
    40441 cagctaccaa gaaaaataaa gagaactata caaatcaaac atgggcagag ttagaaacag
    40501 ttcttacagc agcaaaatct gtaaacacta acgagtctaa acaaagtgaa gttaatgaag
    40561 ctgttgaaaa attaactgca actattgaaa aattggttga attgtctgaa aagccacgtt
    40621 tgactctatc tattgaaaag agagacatag atcgaaaagt tacggtcacg tatactttgg
    40681 aaaatccagc aaatactcaa ataaaatcaa taactgcaac tctgaaaaaa ggagaggaag
    40741 ttgttaagga ttttgtttta acagaagaaa atcttaaaac taatcattta actgctttgt
    40801 ttgaaaagct agattactac aaagaataca ctctatctac ggatatggta tataacagag
    40861 gaaatgatga tgagacggag agtatttcag aagaactaat tcagctgaat cttaagaaac
    40921 tagaattgaa agatatccag acagtctctc tgatgaaatt tgaaaatggt caagaaagtc
    40981 aggttacaca cttgtctgat aaaccgaccg atttgagtaa attatactta aaagttacat
    41041 catcaacgtc taaggatgct gtgttagccg ttagctctat agaagaagag attgttgaaa
    41101 ataaaaaaat ctttaaaatt catgcagata caccagaatt agtagttcgt aagaaagatg
    41161 gcagtctttc taagggattt gactattaca tggagagagt tatccctcat gatggtgata
    41221 tttattatga ttttaaagac ttgatttcag ctatgacatc taatcctaca ggtacgttta
    41281 ttttagggag agatatttcc tcgcgtaatg taaaaccgga tggaaatgga aaatcttata
    41341 tcaaaggtga atttaaagga aaactacttg gtacaaatga taatgttaga cactcgatct
    41401 ttgacttaga atatccattg tttgatacta taaaatcagg agtcgtgaaa gatattgatt
    41461 tcaagcatgt caatatggta ttcccagata gcaatcaagg agataacgta gcaacaattg
    41521 caagagtaat caaagataag acaaaaattg agaatgttaa tgttgaaggt tatctcgagg
    41581 gtcgagatca tgtagctggt ttagttaata atcttgaagg taattccgaa attgaaaata
    41641 tatcctttac aggaaagatt aagtctaaag gtggtaattc tattacagca ggtattgcag
    41701 gtagaaatat cttatctcgt gttaaacgtg cctatgtaaa tgcaaatatt gaagtccttg
    41761 gttcaacgaa ttcgagtatg cttgttgcag taaatggtac aacattgaat gctagtggag
    41821 gttggggagc ctggggaaga cttactgagt ccgttgctaa agggacgtta gaaattaaac
    41881 gcagtggaca agctggtgga gttactgcaa cagtctggcc ttatggagca attgataagg
    41941 ttgtcagcta tgcaaaagtt accaaaggaa aagaattatt tgggtcagat ggtgatttaa
    42001 ataataattg gtttatgcaa aaaattaata atatttttgg tgttcaaggt atcagctcag
    42061 gtgactcagg gaatgattct aagtttaagc gtatttccga ggaagaagca aagcaaaagg
    42121 ttgcctctta taatattaca gctcccaact tgatgagcga ctcaagtctt ttggtagaca
    42181 gactcaatga aagttggaaa aatactgatc aatttgaaag tatacaggat tatcaatccc
    42241 aaaaccaatt aatttaccag aacttgacta aatttactcc ttattacaat aaagaattta
    42301 ttgttcatga aggaaatgct ctcactcctg aacaggaaat attgaagact aagaaaatca
    42361 aatcgattgt agggttgaaa ggaacagagt tcgttgtaga tggcagtgat attgatacta
    42421 tcatgcttca ttttgaggat ggtagtcaga agcgatataa ggtaacctct actggtaagt
    42481 tttcgataac taatttaccg gaatatcagg ttgaagattt aaatgtggtg tatacatcag
    42541 aacatatagt acatccacta gattcgtcac tgataaataa ccttgttgaa gaattgaaaa
    42601 aagtagaatt gtatacagag tctacttacc aagttctagg tattgataaa gataatgcta
    42661 acaaattgaa tagaactaag agattattct tagatgagtc attagatgct gttaaaacac
    42721 aattgcctac ctttgtaaaa acaatgtttg aaaatgagtg gttgcacatc aatggagaat
    42781 ctagtggagc tgtcgctgct ttacgacaaa aaatcatgga taataagacg gctatattgc
    42841 ttgctttgac ttatatcaat cgttattatg atgttaaatt ctcagactat aatattaaaa
    42901 aactgatgct ctttaaacca actttccatg gtgaaaagat tgatctatta gatcgattaa
    42961 tccgactagg atcatctgga gaaaatagat taaaaggttc agaaaatgca gaaacgttca
    43021 agcagttatt tgctagcgaa acgaagcaga aggatttggt gacttattta gactacaatc
    43081 gctctttgtt gactaattat caaacaacag gggaatggtt taaagaaacg actaaggatt
    43141 atattcaatt tgaggaacgt ccatccttag tagaggagat taaagatgcc aaatatcgag
    43201 tttacgataa tttaaccgca ccgtattatc aaggatatat cctacctctc ttaacgttga
    43261 agaatactca tttagcaatt ttatcgaact atagtactat gacatttgtc agccgtgaaa
    43321 aacgccctaa ttggaaaaat gaagattttg ataagtgggt gaaatatgta gcaactgctc
    43381 atagaaacca tgttgatact tggtataaga ttttacctga taatatcaaa ggtaaaatgg
    43441 ttaaagagaa tgttactgct gtttgggaag gattgagcat cccaggaagt gaatgggtag
    43501 accagaatgc tgtagataga aaaggaagag attacgcccc agctcgagaa ttctttaatc
    43561 ttgtaggtgg tcctatggga ggttggtatg cttaccatgg ttatggtgcg catgctggag
    43621 gaagaaatcg ggttaattat gaggtgtttg atgtattaag tgagtatggt atatcggtct
    43681 ttactcatga attgactcac gttaatgata cttggattta cttaggaggg tatggtagac
    43741 gtgaaaatat gggacctgaa gcttatgctc agggattatt ccagtctcct gttccaggtc
    43801 agccgggttg gggggcgctt ggtctcaata tggcatttga aagaaaaaat gatggtgatc
    43861 taatttataa tgcctcccca actcaatttg aaaataggaa agagttagat agttatatga
    43921 aaaattataa cgatactctc atgatggtgg actacttgga aggagatgca gttatctcta
    43981 aaggtaaaga agctattact aaatggttta aaaaagttga acctaaggtt gttagtcaaa
    44041 cagctcagta tgatacggtt cgtcagttga ctgctgaaga gaaagaaaaa ctttctgttt
    44101 ctagtgttga tgatttagtt gatcaaggat taatgtcaga cagagctgta ggaaataata
    44161 cctataatcc agctgatttt gaaacaagtt atattgcgat agattatatg actggtattt
    44221 atggtggagg aaagaatagt gtaggttcac caggtgcctt gatgtttaaa cataatactt
    44281 tccgtatgtg gggctactat ggttttgaag aaggtgttct aggatatgct tctaataaat
    44341 ttaagcaagc atctagagat gaaggtcatg ctggacttag tgataacttt attatttcta
    44401 agatttccaa aggggaattt ttaactatgg aagcatttaa aaagggatat tttaagaaag
    44461 tagtagaaga gttaaaaact aaaggtattc gtcctgttac tatcaatcaa aaaacatata
    44521 gcacctttga agaattgcaa gaaggattta agcaggctgt tgaaagagat ttgaagaaaa
    44581 atcagttaga tgagagggaa acaagaaact tcaaattcca agttttcaga caacttcttc
    44641 aacaaacaga tagctttaaa acttctatct ttagataatc gaaatctctc atctgctttg
    44701 cggatgaggg ttttcttatt ttatgctata cttaaggtat gcatagaaaa acagtgattg
    44761 attttaggac tttaggggag agatatacct ttacccagcc tattaaagag ttgaaaacga
    44821 gaaatgtaga agaagtggca gatttgctgg cacaagtgga aagctaccaa gagcaaggtt
    44881 attatgtggt ggggtatgtc agctacgagg ctgcacctgc ttttgaggaa aaattagcag
    44941 ttcacaagga tcccctactg ggagagtacc tgctttattt tactgttcat gatagcgtag
    45001 aaacttcccc tattcctctg acttatgagg atattgattt gccctcaaat tggcaggaag
    45061 taacgtctgc agcagactat gaaaaggcca ttgcccagat acaccatcac ttgaggcagg
    45121 gagacaccta tcaggtcaac tacaccgtcc aactcaagca aaagttaagt gccaatcctt
    45181 ttgccatcta caatcgtatg gtggtagagc aggaggcggg ctacaatgcc tatgtggaac
    45241 atgacgagat ggcagtgatt tccatgagcc cagagctctt ttttgagcaa aatgatcgcg
    45301 agttgacaac acgaccaatg aaggggacga ctcagcgtgg ggtaactgac caagaagatc
    45361 ttgaacaggc cagttggttg gaacaggatc ccaaaaatcg ctctgaaaat atgatgattg
    45421 tggacctctt gcgcaatgat atgaaccgta tttctgaagt tgggagcgag cacgtggagc
    45481 gtctgtgcca ggtagagcag tattcaactg tttggcagat gacttcgacc atcaagagtc
    45541 agttgcgaga ggatgtggac cttgttgaaa tcttccgctc actctttcct tgtggttcca
    45601 taacgggtgc accgaaaatt gcgacaatgg agattatcaa gaacttggag cctcaaccgc
    45661 gtggagtcta ctgtggaacg attggtctct tgcttccaaa tggacgacgg atttttaatg
    45721 tggccattcg taccattcaa cttcacaaag gtcaagccat ttatggagtt ggcggaggga
    45781 ttacttggga tagcacatgg gaatctgaat accgagaggt tcatcaaaag gcagcagttc
    45841 tttatcgtaa acaagctcgc ttccaactga ttacgacagg ggaaatcagc cagaagaacc
    45901 tgctgtttga agatcaacat ctggaaagac tgagaaaagc tagtcgttat tttgcctttc
    45961 cttttgatgc agaagacttg ggacacaaga ttgaggaaga gtgtcaggat tgtgaagcta
    46021 atcaagatta ccgcttgcga atcagcctta gcaaatctgg agagatagaa gtcaatcgtc
    46081 aagtattaac ccctctcagt acaagctttt gtcaggccca agtctgcctt caggaagctg
    46141 ctttgaatca atcctttacc tactttaaaa ccactcaccg accgcatttg agcctaggag
    46201 aacaagagaa gatttaccac aataagtcag gagaactgct tgaaacctct ataggaaatt
    46261 tggttctgaa aatcgctgga aaactctaca caccgcctat ccgacttgga atcttgccag
    46321 gaatttaccg tcagcatttg ctagaaacag gacaggtaga agagaaagtc ttgaccttgg
    46381 cagatttaac ccaagcagaa gctatttacg gctgtaatgc agtgagaggc ttgtatgaac
    46441 taagccttga ggagaactag atgaaattga tatttttgca tgggttaggg cagtcagcag
    46501 agtcttggaa agaagttcgg aatctactga cagattatcc ttctgaggct atcgagttat
    46561 ttccttctgg agttagtaac tatcaacaag ctaaagagcg agtttatcag cacctagctc
    46621 aagagacaga accttttgtt ttgattggat tgtccttagg tgctgccctg acactagaac
    46681 tttccagtta cgatttacca aatcttcgag ctttgattct gtcaggatgc ccgcttaaat
    46741 tagcagggaa tatcctattt tatcttcagt tgctgatttt taaactactt cccaaaagag
    46801 tatttgaaaa acagggagca gacaagactc ttatggtcgg agtttctgag gaattgaaga
    46861 cacttgattt aacggatata gcagggactt gctcctatcc aaccttacta atttgtggca
    46921 gcaaagataa accgaatctt agttttatga aagctctcca tagactgtta acagattcgc
    46981 agtttcagat cattcctgat ggccctcatg tcttgaataa ggcaaaacca aaggagtttg
    47041 tagaaaagac cagaagtttc cttgaattgc tgaaataagt ttgataaaat aatattgaaa
    47101 tcgatatcat aattatggga gaaagaaatg aataaacgtc tatttttaaa aatgagtctg
    47161 gtgacgttgc caattttagc cttgttttca caaccagttt tggcggaaga aaacatccat
    47221 ttttcgagct gtaaggaagc ttgggcgaat ggctattcgg atattcacga gagagaacct
    47281 ggttattctg ccaagttaga ccgtgatcat gatggtgtgg cttgcgaatt gaaaaatgct
    47341 cctaagggtg cttttaaagc aaaacagtca acggctattc aaatcaacac aagttcagca
    47401 acaacaagtg gttgggttaa gcaggacggc gcttggtact actttgatgg aaatggaaat
    47461 ctagtgaaaa atgcatggca gggaagctat tacctgaaag ctgatggtaa aatggcacag
    47521 agtgaatgga tttatgactc ttcttatcaa gcttggtatt atttgaaatc agatggttct
    47581 tatgcaaaaa atgcatggca aggagcttat taccttaaat caaacggtaa aatggcacaa
    47641 ggtgagtggg tttatgattc ttcttaccaa gcatggtatt acttgaaatc agatggttca
    47701 tatgctcgca atgcatggca aggaaactac tatttgaaat cagatggtaa aatggctaaa
    47761 ggtgaatggg tttatgatgc cacctatcaa gcttggtatt atttgacatc agatggttct
    47821 tatgcttaca gtacatggca aggaaattac tatctaaaat cggatggtaa aatggctgtc
    47881 aatgaatggg ttgatggtgg acgttattat gttggcgctg acggagtttg gaaggaaggt
    47941 caagcaagta cagtttcttc tagtaatgat agcaatagtg aatattctgc tgctttagga
    48001 aaggcaaaaa gttataattc gttattccac atgtcaaaaa aacgtatgta tagacaatta
    48061 acttctgatt ttgataaatt ttcaaatgat gcagctcaat atgccattga tcatttagat
    48121 gattaacaga tactggtagg cgaaaaaatt ccttataatt catttacgca aacctttgca
    48181 taagtgaatg gattttgata tactagtact gtaagcattt tcaattacta cacaatgaaa
    48241 aaggagaata tgatgagtca aaagattatt gggattgacc ttggtggaac ttctatcaaa
    48301 tttgcaatct taacaacagc aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt
    48361 ttggatgagg gaagtcatat cgttgatgat atgattgagt ctattcaaca tcgtttggac
    48421 ttgcttggat tggcagcagc ggacttccaa ggcattggaa tgggatcacc aggtgtggtt
    48481 gaccgtgaca aagggactgt tatcggtgcc tacaacttga actggaaaac ccttcaacca
    48541 atcaaacaaa agattgaaaa agctttgggc attccatttt tcatcgataa tgatgccaac
    48601 gtagcagctc ttggtgagcg ctggatgggt gctggagata accaaccaga cgttgtcttt
    48661 atgacactcg gtactggtgt tggtggtggt attgtcgcag aaggcaaatt gcttcatggt
    48721 gttgctggtg cagcaggtga acttggtcat atcactgttg actttgacca accaatctca
    48781 tgtacttgtg gtaaaaaagg ctgccttgag acagttgctt cagcaacagg gattgtcaac
    48841 ttgactcgtc gctatgccga tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat
    48901 aacggagaag aagtaactgc taagactgtc tttgatctcg caaaagaagg agacgacctt
    48961 gctttgattg tttatcgtaa cttctcacgt tacttgggaa tcgcttgtgc taacattggt
    49021 tcaatcctaa acccatcaac aatcgtcatc ggtggtggtg tgtcagctgc gggagaattc
    49081 cttctacaag gtgttcaaaa agtttacgat gaaaatagtt tcccacaagt acgcacatct
    49141 actaaattag ctcttgcaac tctaggaaat gacgctggag ttatcggagc agcatcactt
    49201 gtattgcaat aagataatga gagaggaaaa tgctaaccta gagttagtaa tgttcctctt
    49261 ttatttttta tgctatacta gttaggacaa tgaatgaggt gagagtaaat gacaaaagca
    49321 gatacgattt ttaaagagaa tattgaacgc attctaaagg aaggtgtttt ctcagagcag
    49381 gctcgtccta agtacaagga tgggactgtt gctaattcca agtatgtaac tggtgccttt
    49441 tccgagtacg acttatctaa aggagaattt cctatcacaa ccttgcgtcc cattgccatc
    49501 aaatccgcca tcaaagaagt tctctggatt taccaagacc agtcaaatag cttagaagtg
    49561 cttaatgaca agtacaatgt tcactactgg aatgactggg aagttggaga cacgggaacc
    49621 attggtgagc gctatggtgc cgttgttaag aaacacgaca ttatcaataa gcttctcaaa
    49681 cagttggaaa ccaatccttg gaaccgccgc aatattattt cgctctggga ttaccaagct
    49741 ttcgaagaaa cagatgggct gctcccgtgc gcctttcaga ccatgtttga tgtccgccgt
    49801 atagatggag aaatctatct ggatgcgacc ttgacccagc gctcgaatga tatgctggtg
    49861 gcccaccaca tcaacgctat gcagtatgtg gctttgcaga tgatgattgc caaacatttt
    49921 ggctggaagg ttgggaagtt cttctacttc atcaacaacc tccatatcta tgataatcaa
    49981 tttgaacaag ctcaggaatt gctccgtcgg gagccgtcaa actgccaacc acgcttggtt
    50041 ttaaatgttc ctgatgggac taatttcttt gatatcaaag cagaagattt tgagttggtg
    50101 gattatgacc ctgttaagcc acagttgaag tttgacctag ctatttaaaa gaatagaaaa
    50161 aagaagttga gaataatccc aacttctttt gtttcttaac gtgatacgcg gcgacgagct
    50221 gcttttttac ggttttcttc gatgaaagct gctttttgct cttctggttc gattactttc
    50281 tttttaaatg cgtatactgc acctgcaacg gcagcgacag ttcctgcgac acctgttaca
    50341 agacctttag cgaatccttt agccatgagt cttcctcctt tatattctca atcagccagc
    50401 ctcctcaaga ggtcacattt ttctgactga cctttttgtg ttataataat agtaacgaaa
    50461 aaatgggaat ttttcaagga aaaaagatga aaacaaaaat aattgtgatt gttggaccga
    50521 ctgctgttgg aaagacggct ctagctattg aagttgcaaa gcgttttaat ggcgaagtgg
    50581 ttagtggaga tagccagcaa gtctatcgag gacttgatat tgggacggcc aaggctagtc
    50641 cagaagagca ggcagctgtt cctcatcatt taatcgatgt tagagagata accgagtctt
    50701 actcggcttt tgattttgtt tcagaagcta agatgactat tgagggtatt cacaaccgtg
    50761 gcaagctagc cattatcgcc ggtgggactg gactttatat ccagagcttg ctagaaggtt
    50821 accacctagg tggggagact cctcatgagg agattttagc ttatcgagct agtttggagc
    50881 catattcaga tgaggaatta gcccatttgg tggatcaagc aggccttgag attccccagt
    50941 ttaatcgtcg tcgtgctatg cgtgccttag aaattgccca ttttggtcag gatttggaaa
    51001 atcaagagac cttgtatgaa ccgctgatta tctgcttgga tgatgaacgt agtcaacttt
    51061 atgagcgtat caaccaccga gtggatttga tgtttgaggc tgggcttttg gatgaggcca
    51121 agtggctgtt tgaccattcc cctaatgtac aggctgctaa aggaattggc tataaggaac
    51181 tctttcctta tttccgtgga gagcagacct tggaggaagc tagtgagagt ctcaaacagg
    51241 cgacccgtcg ttttgccaag cgtcagctga cctggttccg taatcgcatg caggtcacct
    51301 tttatcagat tggagaatct ggtgtacaag accgcatttt aagccagata gaggagtttt
    51361 tagatgattg aaacggagaa aaaagaggag cgagtcctgc tgattggtgt ggaattgcag
    51421 ggtatggaca gttttgacct ctccatggaa gaattggcta gtttagcgaa aacggcaggg
    51481 gcagtcgttg tagatagcta cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc
    51541 ggctctggta agttggaaga gattgcgctt atggtggatg cagaagaaat cactactgtc
    51601 atcgtcaaca accgtctgac cccaaggcag aatgtcaatc tagaggaagt tctcggtgtt
    51661 aaggtcattg accgtatgca gttgattttg gatatctttg ccatgcgggc tcgaagccat
    51721 gaagggaagc tccaagtcca cctagcccaa ctcaaatacc ttttgcctcg cttggttggt
    51781 caggggatta tgctcagccg tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc
    51841 cagctggagc tgaaccgtcg tagcgttcgc aatcaaatca cggatattga gcgccagctc
    51901 aaggtggttg agaaaaatcg ggcgactgtc agagaaaaac gtttggagtc tagcactttt
    51961 aagattggtt tgattggtta tactaatgct gggaaatcaa ctatcatgaa catcttgacc
    52021 agtaagaccc agtatgaagc agatgagctc tttgcgactc tggatgcgac aaccaagagt
    52081 attcatctgg gaggcaatct ccaagtaact ttgacagata ccgttggctt tatccaagat
    52141 ttgccgacag agttggtgtc cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac
    52201 cttctggttc atgttatcga tgctagcaat ccttaccacg aggagcatga aaaaacggtt
    52261 ctctccatca tgaaagacct ggacatggaa gatattcctc acttgacgct ttataataaa
    52321 gcggatttgg tggaggattt cacgcctacc caaacgccat ataccctcat ttctgccaag
    52381 tctgaggaca gtcgtgaaaa cttgcaagca ttattgctag ataagattaa ggaaattttt
    52441 gaagcattta ccctgcgagt gcctttttca aagtcctaca agattcatga tttagagagt
    52501 gttgcaattc tggaagaacg tgattatcag gaagacggcg aagtgattac aggctacatt
    52561 tccgagaaaa ataaatggag gttagaagaa ttttatgact gatattaaaa ctttggctct
    52621 aaagtatgga ggttatacaa gtctggacaa ggtctatctg gatcagcttc tagctggtaa
    52681 aacagagcag gagcagttaa cacttattac acctccgcca agtgttgtta atgcctactt
    52741 tgcagaactc tatcagaaaa aaagtcctca ggctgcgacg gattattttg cagaactcag
    52801 tcaggaactg aatctttaca atactgagcc aagtttcacc ctagaaaata agccttttat
    52861 tcggcttaat ctgtctggta aatcctttgg tttttgttat gagagtgacg gctttggtcg
    52921 gattttctct gaaaatgagg agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat
    52981 tttctcccat caattagtct ttgaagagtc tggtaagatt tacatgaagc ctgtcaagga
    53041 cgaggaagtt gtcagcctag aaagtctcac agctttgact gatttggaaa gattggctga
    53101 tggtcgaaaa cgtctcaaag gctacagcca agaggattta ttgcaagaag ctgctgcttt
    53161 ttctggcaaa cgctatttcc gatcggaaaa ccgcacagcc atgttatata ttgattaatt
    53221 agaaagtatc gaatggatat tcaattttta ggaacggggg ctggtcagcc ctctaaagcc
    53281 cgcaacgttt caagtctcgc cctgaaactt ttggacgaga ttaacgaagt ttggctcttt
    53341 gactgtggag aaggtacgca aaatcgcatt ctggaaacca caattcgacc acgtaaggtc
    53401 agcaaaatct ttattactca tctgcatgga gaccacattt ttggtttgcc aggtttcctt
    53461 tctagccgtg cctttcaggc caatgaagag cagacagatt tggaaatcta cggacctcaa
    53521 ggaatcaagt catttgtctt aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc
    53581 attcatttcc atgagtttga ccaagattct ctgggtaaaa ttcttgaaac cgataaattc
    53641 actgtgtatg cagaggagct ggaccacact attttctgtg ttggctatcg tgtcatgcaa
    53701 aaggatctag aagggacgct ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc
    53761 ccgctttttg gtaaaatcaa aaacggccag gatcttgttt tggaagacgg aactgaaatc
    53821 aaggcagcag actatatctc agcgccacgt ccaggtaaga ttatcactat tttaggagac
    53881 actcgaaaaa cggatgccag tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag
    53941 tccacttatg gcaagggtga tgaaaaaatt gctcgtaacc atggtcactc aactaatatg
    54001 caagctgcac aagtagcggt agaagcaggt gccaaacgcc tcctactcaa ccatatcagt
    54061 gcccgtttcc tctcaaaaga tataagcaaa ctcaagaagg acgctgccac aatttttgaa
    54121 aatgtccatg tggtcaaaga cttggaagaa gtggaaatct agcagtcaca gaaaggataa
    54181 gtatgcctac tattctcatt accggagcta gcggtggtct agctcaagaa atggtcaaac
    54241 tcctgcccaa tgaccaactc atcttgcttg gtagaaataa ggaaaaatta gcccaactct
    54301 acggaaatta ttcccatgca gaattgattg aaattgatat taccgacgat tcagccctag
    54361 aagctctggt aactgatctt tatctccgct atggcaagat tgatgtcttg attaacaacg
    54421 ctggttacgg gatttttgag ggatttgacc agattgctga taaagatatt caccagatgt
    54481 ttgaggtcaa tacctttgcc ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg
    54541 aaagcagcaa agggcatatc atcaacatcg tcagcatggc aggtctaata gctactggca
    54601 agtctagtct ttactcagcg accaagtttg cggctattgg tttttcaaat gctctgcgac
    54661 tcgaacttat gccctatgga gtctatgtga caacagtcaa tccaggacca atccgtacag
    54721 gatttttcga ccaagccgac ccagatggaa cttatcttaa atcggttgac cgcttcctgc
    54781 tagaaccaga tgcagtggct aaaaagattg tcaagattat aggaaaaaac aaacgagaac
    54841 tcaatctccc gattttgttg aacctagctc ataagtttta taccctcttt cctaagctag
    54901 ctgataagtt ggcaggggaa acttttaatt ataagtaaaa agaaccaatg tgcaggttgt
    54961 tgctagccta catattggtt cttatcattt ctcaactatc aaactgaact tcttctagga
    55021 ggtagtctat aaagcgttcg cccatcttag ataggctggt tttctcatgc tggatataga
    55081 ccagctcaat cgggtcatca atatccagtg ggatagaaac gatattgtct ccgtttaggt
    55141 tgctgttcaa aatccctgtc gcaatggtat aaccatccaa accaatcaag agattaaaga
    55201 gggtggcacg gtcactgacc acaatggatt tcttgtggtg ttcttgagaa agaatctctt
    55261 ctgaaaagta gaaggagttg tgcgtccctt ggtcatagct gaggtaaggg aaattctcca
    55321 aatcagacag tttcaccttg tctttctttg ccagagggtt ggtcttgctg acaaagatat
    55381 gtggttgcgc tgtgaagaga tggtgggcta gcaggtgatt gtcatccagc atcttggtta
    55441 aaacatcacg gttgtaactg tttaagaaga ggaccccgac ctcactgcgg aagttcttga
    55501 cgtcgtcgat aatctcccaa gtccgagttt cacgaaggaa gagttcgtat ttctccatat
    55561 cgcttttctt gagcaaagag acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa
    55621 cgctaaatag ttcgcggtgg gcgacaggat ttttatagcg ttcctccaga agctgggtct
    55681 gctcgacaac ctgacgggca taggagagaa actccatccc atcacgggtc aaggtgattc
    55741 ccttgggatt gcggataaag atctcaatgc ccatttcatt ttccaaatct cgcactgcat
    55801 tggagagact tggctgagtg ataaagagtt gcttggctgc ctcattcatg gagccagttt
    55861 cgacgatttt gataatataa tgtaattgtt gaattctcat gtttttattg taccatactt
    55921 gccttagaat cgctaaagaa gatgggaaaa taaggagcat tgtgtgagtc tcttcttgaa
    55981 aaaaacacaa aattttgcta gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt
    56041 cctcaaacga tttggtatta ttgtttacat gggaaaacgc ttatatgata ttgaactgat
    56101 gaagttggaa ctatctcgga tttacgatgc agggttgatg gataaattag actatctaga
    56161 ggcagaagca gttcttcgca gagagcacaa ggtagaattg gattatattg agaaaaatgg
    56221 agaaaagaac taatggttac ttggattttg tgggcactta tactagcaat gttggcgtgg
    56281 atgggcttta actatcttcg tattcgccgt gcggctaaaa ttgtggacaa tgaggagttt
    56341 gaagccttga ttcgtacggg tcaattgatt gatttgcgcg acccagcaga attccacaga
    56401 aaacatatcc ttggtgcacg caatattcct tcaagtcagt tgaaaactag tcttgcagcc
    56461 cttcgtaaag ataaacctgt ccttctctac gaaaaccaac gtgcgcaacg agttacaaat
    56521 gcagctcttt acttgaaaaa acaaggtttt tctgagattt atatcctttc ttatggcttg
    56581 gattcttgga aagggaaagt gaagactagc taaccttatt tccaaattag ttgaatgata
    56641 g
//
LOCUS       DAVLBN010000006        47046 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLBN010000006 DAVLBN010000000
VERSION     DAVLBN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.006"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VXC24_000328"
     CDS             complement(<1..137)
                     /locus_tag="VXC24_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0492502.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            307..378
                     /locus_tag="VXC24_000329"
     tRNA            307..378
                     /locus_tag="VXC24_000329"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:340..342,aa:Glu,seq:ttc)
     gene            384..457
                     /locus_tag="VXC24_000330"
     tRNA            384..457
                     /locus_tag="VXC24_000330"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Asn,seq:gtt)
     gene            complement(498..1040)
                     /locus_tag="VXC24_000331"
     CDS             complement(498..1040)
                     /locus_tag="VXC24_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0492503.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1300..2553)
                     /locus_tag="VXC24_000332"
     CDS             complement(1300..2553)
                     /locus_tag="VXC24_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0492504.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2909..4667
                     /locus_tag="VXC24_000333"
                     /pseudo
     CDS             2909..4667
                     /locus_tag="VXC24_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(4697..7240)
                     /locus_tag="VXC24_000334"
     CDS             complement(4697..7240)
                     /locus_tag="VXC24_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0492505.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7302..8924)
                     /locus_tag="VXC24_000335"
     CDS             complement(7302..8924)
                     /locus_tag="VXC24_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0492506.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9130..10155
                     /gene="trpS"
                     /locus_tag="VXC24_000336"
     CDS             9130..10155
                     /gene="trpS"
                     /locus_tag="VXC24_000336"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0492507.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10307..11785
                     /gene="guaB"
                     /locus_tag="VXC24_000337"
     CDS             10307..11785
                     /gene="guaB"
                     /locus_tag="VXC24_000337"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0492508.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VXC24_000338"
     CDS             complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VXC24_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0492509.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VXC24_000339"
     CDS             complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VXC24_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0492510.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13463..14713
                     /locus_tag="VXC24_000340"
     CDS             13463..14713
                     /locus_tag="VXC24_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0492511.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14710..15993
                     /locus_tag="VXC24_000341"
     CDS             14710..15993
                     /locus_tag="VXC24_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0492512.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16035..16856
                     /locus_tag="VXC24_000342"
     CDS             16035..16856
                     /locus_tag="VXC24_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0492513.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16867..17412
                     /gene="pgsA"
                     /locus_tag="VXC24_000343"
     CDS             16867..17412
                     /gene="pgsA"
                     /locus_tag="VXC24_000343"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0492514.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17409..18236
                     /locus_tag="VXC24_000344"
     CDS             17409..18236
                     /locus_tag="VXC24_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0492515.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18221..19060
                     /locus_tag="VXC24_000345"
     CDS             18221..19060
                     /locus_tag="VXC24_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0492516.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19053..19847
                     /locus_tag="VXC24_000346"
     CDS             19053..19847
                     /locus_tag="VXC24_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0492517.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19906..20724
                     /gene="mreC"
                     /locus_tag="VXC24_000347"
     CDS             19906..20724
                     /gene="mreC"
                     /locus_tag="VXC24_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0492518.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20724..21218
                     /gene="mreD"
                     /locus_tag="VXC24_000348"
     CDS             20724..21218
                     /gene="mreD"
                     /locus_tag="VXC24_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0492519.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21312..22490
                     /locus_tag="VXC24_000349"
     CDS             21312..22490
                     /locus_tag="VXC24_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0492520.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22714..23493
                     /gene="rpsB"
                     /locus_tag="VXC24_000350"
     CDS             22714..23493
                     /gene="rpsB"
                     /locus_tag="VXC24_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0492521.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23559..24599
                     /locus_tag="VXC24_000351"
     CDS             23559..24599
                     /locus_tag="VXC24_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0492522.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24845..25168
                     /gene="tnpB"
                     /locus_tag="VXC24_000352"
     CDS             24845..25168
                     /gene="tnpB"
                     /locus_tag="VXC24_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0492523.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(25309..25596)
                     /locus_tag="VXC24_000353"
                     /pseudo
     CDS             complement(25309..25596)
                     /locus_tag="VXC24_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25587..25985
                     /locus_tag="VXC24_000354"
     CDS             25587..25985
                     /locus_tag="VXC24_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492524.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VXC24_000355"
     CDS             complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VXC24_000355"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0492525.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(27387..28022)
                     /locus_tag="VXC24_000356"
     CDS             complement(27387..28022)
                     /locus_tag="VXC24_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0492526.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            28078..29376
                     /locus_tag="VXC24_000357"
     CDS             28078..29376
                     /locus_tag="VXC24_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0492527.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29373..30035
                     /locus_tag="VXC24_000358"
     CDS             29373..30035
                     /locus_tag="VXC24_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0492528.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            30115..30663
                     /gene="raiA"
                     /locus_tag="VXC24_000359"
     CDS             30115..30663
                     /gene="raiA"
                     /locus_tag="VXC24_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0492529.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            30799..32772
                     /locus_tag="VXC24_000360"
     CDS             30799..32772
                     /locus_tag="VXC24_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0492530.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            32769..33221
                     /gene="rplI"
                     /locus_tag="VXC24_000361"
     CDS             32769..33221
                     /gene="rplI"
                     /locus_tag="VXC24_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0492531.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            33265..34617
                     /gene="dnaB"
                     /locus_tag="VXC24_000362"
     CDS             33265..34617
                     /gene="dnaB"
                     /locus_tag="VXC24_000362"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0492532.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            34619..34885
                     /locus_tag="VXC24_000363"
     CDS             34619..34885
                     /locus_tag="VXC24_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492533.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            34974..36320
                     /gene="cbpD"
                     /locus_tag="VXC24_000364"
     CDS             34974..36320
                     /gene="cbpD"
                     /locus_tag="VXC24_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0492534.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      36403..36505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            36576..36866
                     /locus_tag="VXC24_000365"
     CDS             36576..36866
                     /locus_tag="VXC24_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0492535.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFSNVKINVGEILSIDEKLEKYTETTH"
     gene            36829..37587
                     /locus_tag="VXC24_000366"
     CDS             36829..37587
                     /locus_tag="VXC24_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492536.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            37625..38632
                     /locus_tag="VXC24_000367"
     CDS             37625..38632
                     /locus_tag="VXC24_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0492537.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            38632..39360
                     /locus_tag="VXC24_000368"
     CDS             38632..39360
                     /locus_tag="VXC24_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492538.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            39479..39937
                     /locus_tag="VXC24_000369"
     CDS             39479..39937
                     /locus_tag="VXC24_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0492539.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            39939..42371
                     /locus_tag="VXC24_000370"
     CDS             39939..42371
                     /locus_tag="VXC24_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0492540.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            42692..43345
                     /gene="rr06"
                     /locus_tag="VXC24_000371"
     CDS             42692..43345
                     /gene="rr06"
                     /locus_tag="VXC24_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0492541.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            43342..44673
                     /gene="hk06"
                     /locus_tag="VXC24_000372"
     CDS             43342..44673
                     /gene="hk06"
                     /locus_tag="VXC24_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0492542.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            44768..45295
                     /locus_tag="VXC24_000373"
     CDS             44768..45295
                     /locus_tag="VXC24_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0492543.1"
                     /translation="MVLAIILVIFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            45374..>47046
                     /gene="pspC"
                     /locus_tag="VXC24_000374"
     CDS             45374..>47046
                     /gene="pspC"
                     /locus_tag="VXC24_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0492544.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLVMGSVVHATEKEVTT
                     QVPTYSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAK
                     AQKEEDRRNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTIKQAKAKVES
                     KQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKDKLKRRTKRAVPGEPATPDKKENGA
                     KSSDSSVGEETLPSPSLKPEKKVAEAEKKVAEAEKKAKDQKEEDRRNYPTNTYKTLEL
                     EIAESDVKVKEAELELVKEEAKESRNEEKVKQAKAKVESKQAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNG
                     SWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGS"
BASE COUNT        14838 a         7753 c        10094 g        14361 t
ORIGIN      
        1 tttcctttct gttgataggc tagtaacaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatat tttagagaaa
      241 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
      301 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
      361 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
      421 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
      481 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
      541 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
      601 tgagttagat agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat
      661 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
      721 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
      781 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
      841 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
      901 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
      961 aatggctgtt ccatcagtaa ttgtaccata gcgttttcaa tagttcgctt tgtttttaag
     1021 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
     1081 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
     1141 gacaatatgt ttaaaaaagt ctagtggtaa aatgtcaagc gaccccccgc tcaaagtttg
     1201 aaaactattt caaaaaaagg gtgcactaaa gaagccctac tgaaaacgat gttttcacac
     1261 tgtttttagt agattttcaa ggagaggtgc agatataact tagttatctt ccataatcct
     1321 ccttggtggc gtatagagtt gatggttgcg tagtagcaca tccaccagac gcacaaattt
     1381 tctagcggtt agtaagatgg ctcgtttgtg ttggtgttta ggtacttcat ggtatttctt
     1441 cttatagaaa tccttgtatt cgtcatcata acgccttacc gagttggcgg cttcaaccag
     1501 gtagtagcgc agataacgat tgcccctatt cacaagcgaa gtatgttgtg agtttgagtt
     1561 accagattgc ttttctctcc aattcagacc agcaaatttt gcgacctggg gatggtcttt
     1621 aaagcgttcg atttgtccaa tttcggcaat gataccagca gcgtagacct tcccgacccc
     1681 aggtatggag gtcaggcatt gatattcagg aatggtttcc accatatctt caatggcctt
     1741 atcaatttcc ttgatcattt tttccaggtt tcgaatttcc cgagccagaa gtccgagaat
     1801 gacattgact gaatcttgtt ggagtttaga gaggcgataa gaacctctga tagcggcttg
     1861 aatggtttga gcaagcttct cagagtcctt aaaatgccct ttacccagtt tttggagcca
     1921 atcatctaat tcttgaagag gcatgttagc aagttcgtct aaggtcatct catctgtcat
     1981 caaggtcatc atcgttgaac tccataggtt agtagagagt tcttctttct tgaattgata
     2041 agccaaggta ttgcacttgt agtagatatt ttcaatgaag tgctgtttgg ttctggttaa
     2101 ttgctcgatg atttggagtc tggttcttgt gagatgttgg agagccatgt atttctcttc
     2161 ttttaaaaaa gaaggtgaaa atcgctcaat acggaaataa tccgcaatgt agaaagcatc
     2221 aatggtatcg tttttgtttt cttcgaaagc atcccgatac ttcttgattt tattaggttg
     2281 ttcgaccata atctcaacat gtagttcttt caactgccta tcttcatgga agaacatagc
     2341 agggtggaaa ctgtagagac tggttgcttc catgccaatg acaatccttt cgaagtgata
     2401 ggtatgattc aaatcaagga tatgattctt aatctctgtt gccccagaaa ggtcattaga
     2461 gagggaagca gtgacggggg tgctagtatc actcaacatg atacacacat ctaattttgt
     2521 agagctgatg tctaaaccga caaaacattt cattaaggaa ggtctccttt ccattagatt
     2581 tggaagtttt tttgactact gtaaggtttc ccagaaacac cttgttccaa catcctcgca
     2641 taagagaatc cttatcacag cctgacagag ccgcctgcat cctactagat acagaagtca
     2701 agctgtggaa acagctagtg tgttggaagt ttgaacaagg cttgggtaac agacttttta
     2761 atgaagtcca agcaacaagg agaaaaagaa acaaccatga gtccattcca tgactctatt
     2821 gttctagaaa accttgcaat agtcaagtga taacgaataa aacttgggat tgaaatatcc
     2881 ccatgattat atattacgag gagaaactat gtttaaagaa tggaaagcaa tttaaaaaaa
     2941 acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta caatatcata
     3001 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
     3061 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
     3121 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
     3181 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctgaa
     3241 aaagcaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
     3301 caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
     3361 cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt acaaaatcaa
     3421 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
     3481 tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac tagcaaatta
     3541 gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
     3601 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcta ccttgacagg tagtttggat
     3661 caattagttt caggctcaaa caccttgaca caaaaatctt ctagcttgac agcaggagtt
     3721 ggtcaattag ttgaaaaaac tccagaatta gtatctggta ttgaaaaatt atcaactggc
     3781 tccaattaat tgaatcaaaa gagtcaagaa ttgatagcag gagttgataa attgcagtca
     3841 ggctctagcc aactagctga caaatccagt cagttacttt caggtgtttc tcaattagaa
     3901 agtggagcta ataaattggc agatggagct gggaaactag cagaaggtgg aacaaagtta
     3961 acttctggat tggaaggttt acagacagga cttgcttctt taggacaagg actaggtaat
     4021 gctagtgatc aactcaaatc agcatcaaca gaatctaaaa atgcagagat tttgtcaaat
     4081 ccactcaatc tttccaaaac agacaatgac caagttcctg taaatggaat tgcaatggct
     4141 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacgaatat gatctttgcg
     4201 aagttacctt caggacgtca tccagagagc cgttgggctt ggttgaaatc tcgagctgaa
     4261 ataaatggta ttatagctgt tttggcaggg attttggtat atggaggagt tcatcttatt
     4321 ggtctaactg ctaatcatga aatgagaaca tttattctca tcatcttaac aagtttagta
     4381 ttcatgtcta tggtgaccgc tttaacaaca tggaatagcc gtataggagc tttcttctcg
     4441 cttatttttc ttttattaca gttagcatca agtgcaggta cctatccgct tgctttgaca
     4501 aatgatttct ttagagctat taatccttgg ttgccaatga gttattcagt ttcgggatta
     4561 cgacaaacaa tctccatcaa caagtcattt tcctagctgt catactagct ctatttactg
     4621 gtttaggtat gctagcctat caacctaaga aaatggaaga agattaaaaa aatcgaccga
     4681 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
     4741 gtaagagaga agtaaaggaa cagattgctc cagtaataaa accattggga atgaaggaaa
     4801 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
     4861 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
     4921 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
     4981 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
     5041 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
     5101 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
     5161 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
     5221 aaaagtgaag gtttatgaaa gagagataaa tttggctgtt ttctggaact tcaatttgat
     5281 actggattgc tgcatcctca tttgaagaac ttgtgacact aatcaaatta ttagtatttt
     5341 ctattttttc ataagggatt ggagaaaaat aatcaaaatc aacgttagca agttgattta
     5401 aaaacgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     5461 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     5521 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
     5581 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     5641 aggatttaaa cccaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     5701 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     5761 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     5821 ctcgactata agtacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     5881 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     5941 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     6001 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     6061 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     6121 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     6181 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     6241 ctatgtaaaa gcttgcaatt agaaatgcaa agaataatac atatatgagt ttcacgtgaa
     6301 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaaaggaagt agtccaacaa
     6361 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     6421 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     6481 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     6541 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     6601 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     6661 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     6721 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     6781 ctaattgact gacagtgaaa ctcatcagag tataggaagt agataaggct agttttaaag
     6841 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     6901 caaattttaa gagagtggtc agataaacag catctggcat attcgttaga tcaaaaaagt
     6961 aaaccagagg tgagagaaaa ctacccaagt aataactaga cagagcatag aagtttagcc
     7021 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     7081 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     7141 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgagag
     7201 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     7261 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     7321 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     7381 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     7441 tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     7501 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     7561 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     7621 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
     7681 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     7741 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     7801 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     7861 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     7921 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     7981 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     8041 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     8101 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     8161 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     8221 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     8281 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
     8341 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     8401 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     8461 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     8521 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     8581 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     8641 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     8701 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     8761 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     8821 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     8881 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     8941 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
     9001 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     9061 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     9121 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     9181 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     9241 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     9301 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     9361 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     9421 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     9481 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     9541 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     9601 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     9661 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     9721 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     9781 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     9841 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     9901 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     9961 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    10021 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    10081 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    10141 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    10201 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    10261 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    10321 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    10381 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    10441 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    10501 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    10561 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    10621 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    10681 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    10741 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    10801 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    10861 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    10921 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc gtcttctagt
    10981 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    11041 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    11101 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    11161 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    11221 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    11281 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    11341 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    11401 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    11461 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    11521 ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg
    11581 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    11641 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    11701 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    11761 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    11821 tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa tagtgaagat
    11881 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    11941 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    12001 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
    12061 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    12121 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    12181 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    12241 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    12301 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    12361 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    12421 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    12481 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    12541 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    12601 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
    12661 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    12721 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
    12781 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    12841 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    12901 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    12961 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    13021 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    13081 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    13141 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    13201 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    13261 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    13321 tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat gtaagcgatt
    13381 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    13441 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    13501 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    13561 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    13621 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    13681 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    13741 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    13801 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    13861 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    13921 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    13981 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    14041 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    14101 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    14161 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    14221 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    14281 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    14341 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    14401 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    14461 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    14521 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    14581 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    14641 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    14701 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaaag
    14761 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    14821 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    14881 gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    14941 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    15001 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    15061 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    15121 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    15181 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    15241 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    15301 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    15361 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    15421 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    15481 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    15541 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    15601 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    15661 agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc tttgtctcat
    15721 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    15781 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    15841 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    15901 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    15961 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    16021 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    16081 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    16141 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    16201 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    16261 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    16321 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    16381 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    16441 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    16501 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    16561 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    16621 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    16681 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    16741 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    16801 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    16861 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    16921 cctattttta tctttatttt gacgatagga aattcgatag agagtcatat agttgcagct
    16981 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    17041 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    17101 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    17161 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    17221 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgctattatt
    17281 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    17341 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    17401 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    17461 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    17521 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    17581 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    17641 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    17701 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    17761 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    17821 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    17881 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    17941 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    18001 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    18061 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    18121 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    18181 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    18241 tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    18301 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    18361 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    18421 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    18481 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    18541 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    18601 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    18661 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc catctatatt
    18721 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    18781 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    18841 tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    18901 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    18961 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    19021 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    19081 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    19141 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    19201 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    19261 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    19321 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    19381 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    19441 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    19501 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    19561 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    19621 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    19681 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    19741 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    19801 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    19861 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    19921 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    19981 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    20041 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    20101 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    20161 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    20221 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    20281 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    20341 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    20401 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    20461 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    20521 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    20581 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    20641 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    20701 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    20761 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    20821 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    20881 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    20941 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    21001 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    21061 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    21121 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    21181 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    21241 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    21301 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    21361 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    21421 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    21481 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    21541 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    21601 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    21661 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    21721 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    21781 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    21841 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    21901 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    21961 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    22021 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    22081 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    22141 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    22201 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    22261 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    22321 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    22381 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    22441 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    22501 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    22561 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    22621 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    22681 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    22741 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    22801 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    22861 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    22921 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    22981 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    23041 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    23101 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt
    23161 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    23221 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    23281 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    23341 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    23401 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    23461 atcgttgaag ttgtagaagg tgacaacaaa tagtaattac ctaggagggc ggggcttagc
    23521 ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac
    23581 ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg
    23641 tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta
    23701 aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg
    23761 gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc
    23821 aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaata
    23881 atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat
    23941 ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa
    24001 cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag
    24061 ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga
    24121 aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac
    24181 aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc
    24241 ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg
    24301 aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa
    24361 ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac caagcttaca
    24421 cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat
    24481 cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag
    24541 ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat
    24601 aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg
    24661 ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat aataagggct
    24721 aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac aaggtatcta
    24781 tcctaattcc ccaacttcca gtataccaga taaaaaataa ttatcggagg aaaggtattg
    24841 tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga
    24901 tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc
    24961 tttctccgat caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagttcttta
    25021 ctgggatggt caaggatttt ggatattata taaacgcttt gagaacggaa aactgacttg
    25081 gtccagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagatt ggctgatgaa
    25141 gggcttttct atcactcccc aaatatagtg gatttaaact agaatagtac acctctgctt
    25201 ctaaaacatt gttagaaatc gatttgacta tcctgttctt atttcatttt actataaatt
    25261 catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc atctgttttc
    25321 aaaaagcatt ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc
    25381 ttgtatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    25441 tttccacact tgttcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
    25501 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
    25561 taaaagataa tcatctggat aagcttgtga aagctcctat tcctaaagcc cctttagcgc
    25621 ataactttgg ctcagcttct attatcgctc acaccatcca tcagaagttt aatctgaagg
    25681 tacccaatta tcgccaagaa gaagattggg ctaggatggg tttaccaatc acacgtaagg
    25741 aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctt tataacctct
    25801 tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct tatagggtgc
    25861 tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa gctgagaaac
    25921 aagggattac gctttaccat catgttctaa tcgatttgtt catatcttat ttcaatccat
    25981 tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg tggaaactct
    26041 cgtaaacaaa gaggttttag aggcctattt accatggact aaagttgtac aagaaaagtg
    26101 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
    26161 atagacttcg ttattggacg gttacaattc ataaagtgct gtagagagat aacgttcacc
    26221 gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg caacctcgat
    26281 ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt ttccaccaat
    26341 ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat cataggcttt
    26401 agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt gaggaccagg
    26461 tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt gaatgttaga
    26521 attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccagtac ctactccagc
    26581 aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc ctgttgttct
    26641 ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac catcacgttc
    26701 agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac caggagttag
    26761 gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca tagtttcagg
    26821 cataacgatg acgactttat accctttagc agcacctacc catgaaagtc caataccggt
    26881 gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat cttgttcagc
    26941 tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat taaatgcttc
    27001 aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt taacaatcgg
    27061 tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac ctctttgtat
    27121 aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat cctatcgaag
    27181 cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat tgcgttcagc
    27241 taattctagt aaataggtgt gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt
    27301 ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt gtgagaatgt
    27361 caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc aacctctcgt
    27421 aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc agctttaata
    27481 gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt aaagtttgta
    27541 tccagctcca tgagaccatg ttctttaagg aagttactgt actcttggta ctgagcataa
    27601 gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat ttctttgaca
    27661 gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag tttaatacca
    27721 ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc tagtacccca
    27781 agcatgggaa caccagcagt accactaggc tcaccatcat cacttgtacg tttaatttca
    27841 ctacgttctc caataatgaa ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg
    27901 atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc atggcagata
    27961 aagcgagatt ttttgatttc ttcttggact tgaccgtcct ctttaattgt cctaaattcc
    28021 atgatttaat tgtactaaaa aatcatctaa agtgctagtt tttacgaata aagaagtatg
    28081 aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac agaagaagaa
    28141 cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact tttctgtcaa
    28201 cgctgtaata gtactattct agaagaatgg tatttgccca tcggtgctta ctattgtcga
    28261 gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt tccgcaggag
    28321 gattttccaa agcaagatgt tctcaaatgg cgcggccaat taactccttt tcaagagaag
    28381 gtgtcagagg gattgcttca agtagtagac aagcaaaagc caaccttagt tcatgcggta
    28441 acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat caatgcgggt
    28501 ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta caagcgcctg
    28561 caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc ttattttcga
    28621 acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc ttttgatttg
    28681 ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccatgct ttaccacgct
    28741 gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac ttcgaccaat
    28801 gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgaatttacc gagacggttt
    28861 catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa tcgctactta
    28921 gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag aaagacagct
    28981 tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttagc agaaatctta
    29041 caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga ggatcgatta
    29101 gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac gacaatcttg
    29161 gagcgcggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa tcatcgtttg
    29221 tttaccaagt ctagtttgat tcagattggt ggacgagttg gacgaagcat ggatagaccg
    29281 acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa ggcgattaag
    29341 gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt gggcagacta
    29401 tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac tcttgtcttt
    29461 gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca aattgtatga
    29521 aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa ggagttgaag
    29581 tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc agtcgctata
    29641 agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt gaggagttga
    29701 aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga tatgctaata
    29761 gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat ctggatttat
    29821 tagagaaaag agaagagaga gccagttctt ctaaaaatcg ttcagagcgc ttggggacag
    29881 aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta cttatagatg
    29941 atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa gaagctggtg
    30001 ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg
    30061 aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac tcatatgatt
    30121 aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga ttatgtagtt
    30181 tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga tgcccgaatt
    30241 aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc gcttggatct
    30301 attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga ccttgtaact
    30361 gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat
    30421 aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa tgttgtccag
    30481 tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga agaagcaatt
    30541 ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga agatcagaca
    30601 accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt taaagaatct
    30661 taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt tcttataatt
    30721 gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta tggtataatg
    30781 ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc tattctagta
    30841 ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa taatctgttg
    30901 acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa gaaactgaga
    30961 gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca agcggaagaa
    31021 agtttgacat ctctattgga acaaatgcct gtaggtgtta tgaaattgaa tttatcttct
    31081 ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga agatggtgat
    31141 tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc gtctacttat
    31201 gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg tgttttgtat
    31261 tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag tcgaccagtg
    31321 attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc tgagtcagat
    31381 attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga aaaatacatg
    31441 atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta cacggtgctt
    31501 gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga gtcgaaacag
    31561 agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa tcatgatgag
    31621 atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg cgaccaggtg
    31681 gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct
    31741 tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc agataagatt
    31801 cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga tgctttgggc
    31861 tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta tgctctttat
    31921 gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga aaaagaagga
    31981 gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg ttctttgttg
    32041 attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta tgatttattt
    32101 acccaaacca ttgttattga ccaccataga agggatcagg attttccaga taatgcggtt
    32161 attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga attgattcag
    32221 ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtctt gatggctggt
    32281 atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt tgatgttgct
    32341 agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc tgcgacagat
    32401 tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt aggttcagat
    32461 gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat tagtaaggca
    32521 gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca
    32581 caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca acggattatg
    32641 gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa agatgtaacc
    32701 ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa ggaaaaggag
    32761 aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa
    32821 ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat ctagccaaag
    32881 aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc
    32941 acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg
    33001 ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct attaccaata
    33061 agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa cgtcatattc
    33121 aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa atctatcaag
    33181 atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc ttcttgacaa
    33241 gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt acaacctcaa
    33301 gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag taaacttgtt
    33361 tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg tttgattttc
    33421 caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac ggttcgtact
    33481 atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt ggttgagatt
    33541 gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa
    33601 gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc ttacgaagcg
    33661 tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggttgattga tgtcagtgaa
    33721 aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa ctttggaaat
    33781 ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg ttatcgtgat
    33841 ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc agctcgtcca
    33901 gcagttggta agacagcatt tgccttgaat atcgctcaga atattgggac taagttggac
    33961 aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta
    34021 gctgcagaag gcttggtgga gtcacattct atccgtacag ggcaattgac agatgaggag
    34081 tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta tatcgatgat
    34141 acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc tcaagaaact
    34201 ggaaatcttg gtttgatttt gatagactat ttgcaactta tcacgggaac tggtcgagaa
    34261 aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc caaggaattg
    34321 aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg tcaggacaag
    34381 agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc tgatatcgta
    34441 gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga gggtatccca
    34501 aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa
    34561 ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga ggcataagat
    34621 gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa tcaaggcaca
    34681 tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa aaaatagatt
    34741 gggtaagcta attgaagttt atccatccct atttattgtg gagtttgggg atgtggaagg
    34801 agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc ttacagaaaa
    34861 gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct tttttctccg
    34921 aataatttag gtgaaggcaa tcatcgcttt atattatttt ttaaggagga agaatgaaaa
    34981 ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg
    35041 ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat gcctattcca
    35101 gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa aatgggagcc
    35161 aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta gcctttcgtt
    35221 tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat gaatggggac
    35281 atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt tccattactt
    35341 ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga
    35401 ttgagattga ggaatataac tatggttata cagaatccta taataaacga attataaaag
    35461 caaacacgat gacaggattt attcatttta aagatttgga tggtggcagt gttgggaata
    35521 gtcaatcctc aacttcaaca ggcggaactc attattttaa gaccaagtct gctattaaaa
    35581 ctgaacccct agttagtgca actgtgattg attactatta tcctggagag aaggttcatt
    35641 atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa
    35701 gctatcgtta tgttcaattg gaggctgtga ataaaaatcc tctaggtaat tctgttcttt
    35761 cttcaacagg tggaactcat tattttaaga ccaagtctgc tatcaaaact gaacccctag
    35821 ttagtgcaac tgtgattgat tactattatc ctggggagaa ggttcattat gatcagatac
    35881 ttgaaaaaga cggctacaag tggttgagtt atacggctta taacggaagt cgtcgctata
    35941 tacagctaga gggagtgact tcttcacaaa attatcagaa tcaatcagga aatatctcta
    36001 gctatggatc caataatagt tcaactgtcg gttggaagaa aataaatggt agttggtatc
    36061 atttcaaatc aaatggttct aaatcaacag gatggctgaa agatggttct agctggtatt
    36121 atttgaaatt atctggtgaa atgcagacag gatggttaaa ggagaatggc tcgtggtatt
    36181 atctgggtag ttcaggggca atgaaaacag gctggtacca ggtctctggt aagtggtatt
    36241 attcttactc ttcaggcgcc ttagctgtta atacgacggt ggatggctac agagtaaaca
    36301 gtgatggaga acgagtatag aaaattggag taggagaaat ttcctgctct tttctgtaag
    36361 cagtttcctt gacatttttc ttattttgcg ctatcatata tacatataat atatgggagt
    36421 ctgtgtacag tctgagagga agtgttaaac ttcgaccgca cctgatctgg gtaatgccag
    36481 cggagggaac gatacttagt ctaattttgc accttttcca tgtatggtaa aggtttttct
    36541 ttttttaaaa aggaaaacga gaagaggagg ttcttatgaa agcaagcatt gccttgcaag
    36601 ttttacccct agcacagggg attgatcgga tagctgttat tgatcaggtc attgcttatc
    36661 tgcaaactca agaagtgacg atggtagtga caccatttga aacggtcttg gaaggggagt
    36721 ttgatgagct tatgcgcatt ctaaaagaag cgctggaagt ggcagggcag ggggcagaca
    36781 atgtcttttc caatgtcaaa ataaatgtag gagagatttt aagtattgat gagaaacttg
    36841 agaagtatac tgagacgaca cattagtcta ttgggctttc tcggagtctt gtcaatctgg
    36901 cagttagcag gttttcttaa acttctcccc aagtttatcc tgccgacacc tcttgaaatt
    36961 ctccagccct ttgttcgtga cagagaattt ctctggcacc atagctgggc gaccttgaga
    37021 gtggctttac tggggctgat tttgggagtt ttgattgcct gtcttatggc tgtactcatg
    37081 gatagtttga cttggttcaa tgacctgatt taccctatga tggtggtcat tcagaccatt
    37141 ccgaccattg ccatagctcc tatcctggtc ttgtggctag gttatgggat tttgcccaag
    37201 attgtcttga ttatcttaac aacaaccttt cccatcatcg ttagtatttt ggacggtttt
    37261 aggcattgtg acaaggatat gctgaccttg tttagtctga tgcgagcaaa cccttggcaa
    37321 atcctgtggc attttaaaat cccggttagc ctgccttact tttatgcagg tctgagggtc
    37381 agtgtctcct acgcctttat cacaactgtg gtatctgagt ggttgggagg ttttgagggg
    37441 cttggtgttt atatgattca gtccaagaaa ttgtttcagt atgataccat gtttgccatt
    37501 attattctgg tgtcgattat cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa
    37561 tatgtgatta aatggaaacg tacttaaaat agagcgtttt tgaaaaagaa aagaggaaat
    37621 caaaatgaag aaaacatgga aagtgttttt aacgcttgta acagctcttg tagctgttgt
    37681 gcttgtggcc tgtggtcaag gaactgcttc taaagacaac aaagaggcag aacttaagaa
    37741 ggttgacttt atcctagact ggacaccaaa taccaaccac acagggcttt atgttgccaa
    37801 ggaaaaaggt tatttcaaag aagctggagt ggatgttgat ttgaaattgc caccagaaga
    37861 aagttcttct gacttggtta tcaacggaaa ggcaccattt gcagtgtatt tccaagacta
    37921 catggctaag aaattggaaa aaggagcagg aatcactgcc gttgcagcta ttgttgaaca
    37981 caatacatca ggaatcatct ctcgtaaatc tgataatgta agcagtccaa aagacttggt
    38041 tggtaagaaa tatgggacat ggaatgaccc aactgaactt gctatgttga aaaccttggt
    38101 agaatctcaa ggtggagact ttgagaaggt tgaaaaagta ccaaataacg actcaaactc
    38161 aatcacaccg attgccaatg gcgtctttga tactgcttgg atttactacg gttgggatgg
    38221 tatccttgct aaatctcaag gtgtagatgc taacttcatg tacttgaaag actatgtcaa
    38281 ggagtttgac tactattcac cagttatcat cgcaaacaac gactatctga aagataacaa
    38341 agaagaagct cgcaaagtca tccaagccat caaaaaaggc taccaatatg ctatggaaca
    38401 tccagaagaa gctgcagata ttctcatcaa gaatgcacct gaactcaagg aaaaacgtga
    38461 ctttgtcatc gaatctcaaa aatacttgtc aaaagaatac gcaagcgaca aggaaaaatg
    38521 gggtcaattt gacgcagctc gctggaatgc tttctacaaa tgggataaag aaaatggtat
    38581 ccttaaagaa gacttgacag acaaaggctt caccaatgaa tttgtgaaat aatgacagaa
    38641 attagactag agcacgtcag ttatgcctat ggtcaggaga ggattttaga ggatatcaac
    38701 ctacaggtga cttcaggcga agtggtttcc atcctaggcc caagtggtgt tggaaagacc
    38761 accctcttta atctaatcgc tgggatttta gaagttcagt cagggagaat tgtccttgat
    38821 ggtgaagaaa atccccaggg gcgcgtgagt tatatgttgc aaaaggatct gctcttggag
    38881 cacaagacgg tgcttggaaa tatcattctg cccctcttga ttcaaaaggt ggataaggca
    38941 gaagctattt cccgagcgga taaaattctt gcgaccttcc agctgacagc tgtaagagac
    39001 aagtatcctc atgaacttag cggtgggatg cgccagcgtg tagccttact ccggacctac
    39061 ctttttgggc acaagctctt tctcttagat gaggccttta gcgccttgga tgagatgaca
    39121 aagatggaac tccacgcttg gtaccttgag attcacaagc agttgcagct aacaaccttg
    39181 attattactc acagtatcga ggaggccctc aatctcagtg accgcatcta tatcttgaaa
    39241 aatcgccctg ggcagattgt ttcagaaatt aaactagatt ggtctgaaga tgaggacaag
    39301 gaagttcaaa agattgccta caaacgtcaa atcttggcag aattaggctt agataagtag
    39361 aaaaataggg agttggtgaa gattatcctt taccagcgcc ctttttcttt taaaaatgag
    39421 aaaatttcgg tataatagtc aaacaaggtc aaggtttaaa gagagaggtg ggtttgttat
    39481 gagatttaaa aatacatcgg atcatattga ggcctacatc aaggcgattt tagatcaatc
    39541 tggtatcgtg gagttgcaac ggagtcagtt ggcagatacc tttcaggttg ttcctagtca
    39601 gattaactac gtgatcaaga cacgctttac ggaaagtaga ggctacttgg ttgaaagtaa
    39661 gcgtggtggc ggaggctaca ttcgtatagg acggattgag ttttctagtc atcatgaaat
    39721 gctccgggag ctgctttact cgattggtga gcgagtcagt caagaaattt atgaggatat
    39781 tctccagctt ttggttgagc aggaattgat gaccaagcag gagatgaatt tgctagaatc
    39841 agtagctttg gatcgcgttt taggagaaga agctccagtt gttcgagcaa acatgctacg
    39901 tcagatcata caagaggtag atagaaaagg gaagtaagat gaactattca aaagcattga
    39961 atgaatgtat cgaaagtgcc tacatggttg ctggacattt tggagctcgt tatctagagt
    40021 cgtggcactt gttgattgcc atgtctaatc acagttatag tgtagcaggg gcaactttaa
    40081 atgattatcc gtatgagatg gaccgtttag aagaggtggc tttggaactg actgaaacgg
    40141 actatagcca ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg caggttcttt
    40201 ttgacgaagc agagtatgta gcgtcagtgg tccatgctaa ggtgctaggg acagagcacg
    40261 tcttctatgc gattttgcat gatggcaatg ccttggcaac tcgtatcttg gagagggctg
    40321 gtttttctta tgaagacaag aaagatcagg tcaagattgc tacccttcgt cgaaatttag
    40381 aagaacgtgc aggctggact cgtgaagatc tcaaggcttt acgccaacgc catcgtacag
    40441 tagctgacaa gcaaaattct atggccaata tgatgggcat gccgcagact cctagtggtg
    40501 gtctcgagga ctatacgcat gatttgacag agcaagcgcg ttctggcaag ttagaaccag
    40561 tcatcggtcg ggacaaggaa atctcacgta tgattcaaat attgagccgt aagactaaga
    40621 acaaccctgt cttggttggg gatgctggtg tcgggaaaac agctctggcc cttggtcttg
    40681 ctcagcgtat tgctagtggt gacgtgcctg cggaaatggc taagatgcgc gtgttagaac
    40741 ttgatttgat gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa gaacgcatga
    40801 ataatatcat caaggatatt gaagaagatg gccaagtcat cctctttatc gatgaactcc
    40861 acaccatcat gggttctggt agcgggattg attcgactct ggatgcggcc aatatcttga
    40921 aaccagcctt ggcgcgtgga actttgagaa cggttggtgc caccactcag gaagaatatc
    40981 aaaaacatat cgaaaaagat gcggctcttt ctcgtcgttt cgctaaagtg acgattgaag
    41041 aaccaagtgt ggcagatagt atgactattt tacaaggttt gaaggcgact tatgagaaac
    41101 atcaccgtgt acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg gctcatcgtt
    41161 atttaaccag tcgtcacttg ccagactctg ctatcgacct cttggacgaa gcagcagcaa
    41221 cagtgcaaaa taaggcaaag tatgtaaaag cagacgattc agatttgagt ccagctgaca
    41281 aggccctgat ggatggcaag tggaaacagg cagcccagct aatcgcaaaa gaagaggaag
    41341 tacctgtcta caaagacttg gtgacagagt ctgatatttt gaccaccttg agtcgcttgt
    41401 caggaatccc agttcaaaaa ctgactcaga ctgacgctaa gaaatatcta aatcttgaag
    41461 cagaactcca taaacgggtt atcggtcaag atcaagctgt ttcaagtatt agtcgtgcga
    41521 ttcgccgtaa tcagtcagga attcgcagtc acaagcgtcc gatcggttcc tttatgttcc
    41581 taggacccac aggtgtcggt aagaccgagt tggccaaggc tttggcagaa gttctctttg
    41641 atgacgaatc agcccttatc cgctttgata tgagtgagta tatggagaaa ttcgcagcca
    41701 gccgtctaaa tggagctcct ccaggctatg tgggttacga agaaggtggg gagttgacag
    41761 agaaggttcg caataaaccc tattccgttc tcctctttga tgaggtagag aaggctcacc
    41821 cagatatctt taatgttctc ttgcaggttc tggatgacgg tgtcttgaca gatagcaagg
    41881 gacgcaaggt cgatttttca aataccatta tcattatgac atcgaaccta ggtgcgactg
    41941 cccttcgtga tgataagact gttggttttg gggctaagga tattcgtttt gaccaggaaa
    42001 atatggaaaa acgcatgttt gaagaactga aaaaagctta tagaccggaa ttcatcaacc
    42061 gtattgatga gaaggtggtc ttccatagcc tatctagtga ccatatgcag gaagtggtga
    42121 agattatggt caagccttta gtggcaagtt tggctgaaaa aggcattgac ttgaaattac
    42181 aagcttcagc tctgaaattg ttagcaaatc aaggatatga cccagagatg ggagctcgcc
    42241 cacttcgcag aaccctgcaa acagaagtgg aggacaagtt ggcagaactt cttctcaagg
    42301 gagatttagt ggcaggcagc acacttaaga ttggtgtcaa agcaggccag ttaaaatttg
    42361 atattgcata aaagaataaa agtaccagca tctgaccata agtcacagtg gagtgaaact
    42421 caatgaaaat caaagagcaa actaggcagc tagccgcagg ttgctcaaaa cactggtttg
    42481 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat
    42541 gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat
    42601 tccattatca tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg
    42661 tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga
    42721 aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc
    42781 taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact
    42841 ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca
    42901 cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt
    42961 tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg
    43021 tattaaggcg cttatcagac gttactacgt catagaggat ctttggcgat atcaggatgt
    43081 aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc
    43141 aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga
    43201 gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga
    43261 tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa
    43321 tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta
    43381 agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc
    43441 tttccttttt attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt
    43501 acggagtatt taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca
    43561 aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt
    43621 gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg
    43681 tctgttagta cagcagatgg taaacaggta accgtgcaat ttgttcacgg ggtggatgtc
    43741 tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt
    43801 gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac
    43861 atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt
    43921 aggaaagatg aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg
    43981 aaggttattc atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag
    44041 gtttcctttg tccgcggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt
    44101 atcctagaga atatgcagca taatattgga gattacaaag atcatccaaa atatattgca
    44161 aagagtataa ataagattga ccagatgagc cacttattgg aagaagtact ggagtcttct
    44221 aaattccaag agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat
    44281 attttatcac gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg
    44341 acagatgcta ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg
    44401 attagtaatg caattaaata ttcagataaa aatgggcgtg taatcatatc cgagcaagat
    44461 ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta
    44521 tttgatatat tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt
    44581 ctttacattg tgaataatat tttagaaagc tatcaaatgg attatagttt tctcccttat
    44641 gaacacggta tggaatttaa gattagcttg tagacagatt agttttttat taaagttcac
    44701 atagggttaa cataagtgta ttattcttta tatagataaa aatatagata aaagaaagga
    44761 tactaatatg gtattagcga ttattttagt aatattcctt attcgattga tttttttaaa
    44821 gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga
    44881 gaatacaaaa cgattaacgt tggctcatat tgttttttat ctctcttgcc tcgttgaagc
    44941 aatggtgcat aagacaatgt ttgatggtat gagcatggtt ggtttagtct tgcttatttt
    45001 ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga cagtgaagct
    45061 tatgcttgtc aataatcaca aatatgtaga tcatatctta tttaggacag taaaacatcc
    45121 taattacttt ttaaatatcc ttcctgagtt gattggcttg accttgttga gtcatgccta
    45181 tatgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga
    45241 agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga gataaataca
    45301 aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata
    45361 gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa
    45421 atttagtatt ggagtagcta gtgtagctgt tgccagtctt gttatgggaa gtgtggttca
    45481 tgcgacagag aaggaggtaa ctacccaagt acccacttat tctaatatgg caaagacaga
    45541 acataggaaa gctgctaaac aagtcgtcga tgaatatata gaaaaaatgt tgagggagat
    45601 tcaattagat agaagaaaac atacccaaaa tttcgccttc aacatgaagt tgagcgcaat
    45661 taaaacggag tatttgtatg gattaaaaga gaagtcggaa gctgagttgc cgtcatcgga
    45721 agctgagttg ccgtcagaag taaaagcaaa gttagacgca gcttttgagc agtttaaaaa
    45781 agatacattg aaactaggag aaaaggtagc agaagctgag aagaaggttg cagaagctga
    45841 gaaaaaagcc aaggctcaaa aagaagaaga tcgccgtaac tacccaacca ttacttacaa
    45901 aacgcttgac cttgaaattg ctgagtccga tgtggaagtt aaaaaagcgg agcttgaact
    45961 attgaaagag gaagctaaaa ctcgaaacaa ggacacaatt aagcaagcaa aagcgaaagt
    46021 tgagagtaaa caagctgagg ctacaaggtt agaaaaaatc aagacagatc gtaaaaaagc
    46081 agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagata aactaaagag
    46141 gcggacaaaa cgagcagttc ctggagagcc agcaacacct gataaaaaag aaaatggtgc
    46201 gaagtcttca gattctagcg taggtgaaga aactcttcca agcccatccc tgaaaccaga
    46261 aaaaaaggtt gcagaagctg agaagaaggt tgcagaagct gagaaaaaag ccaaggatca
    46321 aaaagaagaa gatcgccgta actacccaac caatacttac aaaacgcttg aacttgaaat
    46381 tgctgagtcc gatgtgaaag ttaaagaagc ggagcttgaa ctagtaaaag aggaagctaa
    46441 ggaatctcga aacgaggaaa aagttaagca agcaaaagcg aaagttgaga gtaaacaagc
    46501 tgaggctaca aggttagaaa aaatcaagac agatcgtaaa aaagcagaag aagaagctaa
    46561 acgaaaagca gcagaagaag ataaagttaa agaaaaacca gctgaacaac cacaaccagc
    46621 gccggctcct caaccagaaa aaccagctcc agctccaaaa ccagagaatc cagctgaaca
    46681 accaaaagca gaaaaaccag ctgatcaaca agctgaagaa gactatgctc gtagatcaga
    46741 agaagaatat aatcgcttga ctcaacagca accgccaaaa actgaaaaac cagcacaacc
    46801 atctactcca aaaacaggct ggaaacaaga aaacggtatg tggtacttct acaatactga
    46861 tggttcaatg gcgacaggat ggctccaaaa caatggctca tggtactacc tcaacagcaa
    46921 tggcgctatg gcgacaggat ggctccaaaa caatggttca tggtactatc taaacgctaa
    46981 tggttcaatg gcaacaggat ggctccaaaa caatggttca tggtactacc tcaacgctaa
    47041 tggttc
//
LOCUS       DAVLBN010000007        46850 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLBN010000007 DAVLBN010000000
VERSION     DAVLBN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46850
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.007"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..510
                     /locus_tag="VXC24_000375"
     CDS             <1..510
                     /locus_tag="VXC24_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492545.1"
                     /translation="RKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDWNYSD
                     LVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLNFFYK
                     QLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSFSNEY
                     LKTTDEVNR"
     gene            507..1685
                     /locus_tag="VXC24_000376"
     CDS             507..1685
                     /locus_tag="VXC24_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0492546.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            2110..2343
                     /locus_tag="VXC24_000377"
     CDS             2110..2343
                     /locus_tag="VXC24_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0492547.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            2626..4575
                     /gene="mutL"
                     /locus_tag="VXC24_000378"
     CDS             2626..4575
                     /gene="mutL"
                     /locus_tag="VXC24_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0492548.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(4900..5367)
                     /locus_tag="VXC24_000379"
     CDS             complement(4900..5367)
                     /locus_tag="VXC24_000379"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0492549.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(5368..6573)
                     /locus_tag="VXC24_000380"
     CDS             complement(5368..6573)
                     /locus_tag="VXC24_000380"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0492550.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(6593..7228)
                     /gene="ribE"
                     /locus_tag="VXC24_000381"
     CDS             complement(6593..7228)
                     /gene="ribE"
                     /locus_tag="VXC24_000381"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0492551.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(7213..8313)
                     /gene="ribD"
                     /locus_tag="VXC24_000382"
     CDS             complement(7213..8313)
                     /gene="ribD"
                     /locus_tag="VXC24_000382"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0492552.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(8448..8562)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8719..9312
                     /gene="ruvA"
                     /locus_tag="VXC24_000383"
     CDS             8719..9312
                     /gene="ruvA"
                     /locus_tag="VXC24_000383"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0492553.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            9322..9885
                     /locus_tag="VXC24_000384"
     CDS             9322..9885
                     /locus_tag="VXC24_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0492554.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            9882..10559
                     /locus_tag="VXC24_000385"
     CDS             9882..10559
                     /locus_tag="VXC24_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0492555.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(10714..11745)
                     /locus_tag="VXC24_000386"
     CDS             complement(10714..11745)
                     /locus_tag="VXC24_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0492556.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(12000..12683)
                     /locus_tag="VXC24_000387"
     CDS             complement(12000..12683)
                     /locus_tag="VXC24_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0492557.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(12695..13639)
                     /locus_tag="VXC24_000388"
     CDS             complement(12695..13639)
                     /locus_tag="VXC24_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0492558.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            13771..16602
                     /gene="uvrA"
                     /locus_tag="VXC24_000389"
     CDS             13771..16602
                     /gene="uvrA"
                     /locus_tag="VXC24_000389"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0492559.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            16595..17656
                     /locus_tag="VXC24_000390"
     CDS             16595..17656
                     /locus_tag="VXC24_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0492560.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            17788..18186
                     /gene="spx"
                     /locus_tag="VXC24_000391"
     CDS             17788..18186
                     /gene="spx"
                     /locus_tag="VXC24_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0492561.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            18252..18821
                     /locus_tag="VXC24_000392"
     CDS             18252..18821
                     /locus_tag="VXC24_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0492562.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            18908..19174
                     /locus_tag="VXC24_000393"
     CDS             18908..19174
                     /locus_tag="VXC24_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0492563.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            19178..19597
                     /gene="ruvX"
                     /locus_tag="VXC24_000394"
     CDS             19178..19597
                     /gene="ruvX"
                     /locus_tag="VXC24_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0492564.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            19613..19918
                     /locus_tag="VXC24_000395"
     CDS             19613..19918
                     /locus_tag="VXC24_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0492565.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            20331..21581
                     /locus_tag="VXC24_000396"
     CDS             20331..21581
                     /locus_tag="VXC24_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0492566.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            21578..22135
                     /locus_tag="VXC24_000397"
     CDS             21578..22135
                     /locus_tag="VXC24_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0492567.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            22281..23813
                     /gene="cls"
                     /locus_tag="VXC24_000398"
     CDS             22281..23813
                     /gene="cls"
                     /locus_tag="VXC24_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0492568.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            23891..24034
                     /locus_tag="VXC24_000399"
     CDS             23891..24034
                     /locus_tag="VXC24_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492569.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            24071..25609
                     /locus_tag="VXC24_000400"
     CDS             24071..25609
                     /locus_tag="VXC24_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0492570.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            25729..27936
                     /gene="nrdD"
                     /locus_tag="VXC24_000401"
     CDS             25729..27936
                     /gene="nrdD"
                     /locus_tag="VXC24_000401"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0492571.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            27948..28088
                     /locus_tag="VXC24_000402"
     CDS             27948..28088
                     /locus_tag="VXC24_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492572.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            28132..28638
                     /locus_tag="VXC24_000403"
     CDS             28132..28638
                     /locus_tag="VXC24_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492573.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            28631..29221
                     /gene="nrdG"
                     /locus_tag="VXC24_000404"
     CDS             28631..29221
                     /gene="nrdG"
                     /locus_tag="VXC24_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0492574.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            29218..29835
                     /locus_tag="VXC24_000405"
     CDS             29218..29835
                     /locus_tag="VXC24_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0492575.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            30101..30409
                     /gene="rpsJ"
                     /locus_tag="VXC24_000406"
     CDS             30101..30409
                     /gene="rpsJ"
                     /locus_tag="VXC24_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0492576.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            30626..31252
                     /gene="rplC"
                     /locus_tag="VXC24_000407"
     CDS             30626..31252
                     /gene="rplC"
                     /locus_tag="VXC24_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0492577.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            31277..31900
                     /gene="rplD"
                     /locus_tag="VXC24_000408"
     CDS             31277..31900
                     /gene="rplD"
                     /locus_tag="VXC24_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0492578.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            31900..32196
                     /locus_tag="VXC24_000409"
     CDS             31900..32196
                     /locus_tag="VXC24_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0492579.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            32214..33047
                     /gene="rplB"
                     /locus_tag="VXC24_000410"
     CDS             32214..33047
                     /gene="rplB"
                     /locus_tag="VXC24_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0492580.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            33151..33432
                     /gene="rpsS"
                     /locus_tag="VXC24_000411"
     CDS             33151..33432
                     /gene="rpsS"
                     /locus_tag="VXC24_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0492581.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            33444..33788
                     /gene="rplV"
                     /locus_tag="VXC24_000412"
     CDS             33444..33788
                     /gene="rplV"
                     /locus_tag="VXC24_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0492582.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            33801..34454
                     /gene="rpsC"
                     /locus_tag="VXC24_000413"
     CDS             33801..34454
                     /gene="rpsC"
                     /locus_tag="VXC24_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0492583.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            34458..34871
                     /gene="rplP"
                     /locus_tag="VXC24_000414"
     CDS             34458..34871
                     /gene="rplP"
                     /locus_tag="VXC24_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0492584.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            34881..35087
                     /locus_tag="VXC24_000415"
     CDS             34881..35087
                     /locus_tag="VXC24_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0492585.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            35112..35372
                     /gene="rpsQ"
                     /locus_tag="VXC24_000416"
     CDS             35112..35372
                     /gene="rpsQ"
                     /locus_tag="VXC24_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0492586.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            35398..35766
                     /gene="rplN"
                     /locus_tag="VXC24_000417"
     CDS             35398..35766
                     /gene="rplN"
                     /locus_tag="VXC24_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0492587.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            35844..36149
                     /gene="rplX"
                     /locus_tag="VXC24_000418"
     CDS             35844..36149
                     /gene="rplX"
                     /locus_tag="VXC24_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0492588.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            36173..36715
                     /gene="rplE"
                     /locus_tag="VXC24_000419"
     CDS             36173..36715
                     /gene="rplE"
                     /locus_tag="VXC24_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0492589.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            36733..37002
                     /gene="rpsN"
                     /locus_tag="VXC24_000420"
     CDS             36733..37002
                     /gene="rpsN"
                     /locus_tag="VXC24_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0492590.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            37287..37685
                     /gene="rpsH"
                     /locus_tag="VXC24_000421"
     CDS             37287..37685
                     /gene="rpsH"
                     /locus_tag="VXC24_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0492591.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            37877..38413
                     /gene="rplF"
                     /locus_tag="VXC24_000422"
     CDS             37877..38413
                     /gene="rplF"
                     /locus_tag="VXC24_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0492592.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            38497..38853
                     /gene="rplR"
                     /locus_tag="VXC24_000423"
     CDS             38497..38853
                     /gene="rplR"
                     /locus_tag="VXC24_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0492593.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            38871..39365
                     /gene="rpsE"
                     /locus_tag="VXC24_000424"
     CDS             38871..39365
                     /gene="rpsE"
                     /locus_tag="VXC24_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0492594.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            39337..39561
                     /gene="rpmD"
                     /locus_tag="VXC24_000425"
     CDS             39337..39561
                     /gene="rpmD"
                     /locus_tag="VXC24_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0492595.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            39706..40146
                     /gene="rplO"
                     /locus_tag="VXC24_000426"
     CDS             39706..40146
                     /gene="rplO"
                     /locus_tag="VXC24_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0492596.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            40159..41469
                     /gene="secY"
                     /locus_tag="VXC24_000427"
     CDS             40159..41469
                     /gene="secY"
                     /locus_tag="VXC24_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0492597.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            41620..42258
                     /locus_tag="VXC24_000428"
     CDS             41620..42258
                     /locus_tag="VXC24_000428"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0492598.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            42375..42593
                     /gene="infA"
                     /locus_tag="VXC24_000429"
     CDS             42375..42593
                     /gene="infA"
                     /locus_tag="VXC24_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0492599.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            42618..42734
                     /gene="rpmJ"
                     /locus_tag="VXC24_000430"
     CDS             42618..42734
                     /gene="rpmJ"
                     /locus_tag="VXC24_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0492600.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            42752..43117
                     /gene="rpsM"
                     /locus_tag="VXC24_000431"
     CDS             42752..43117
                     /gene="rpsM"
                     /locus_tag="VXC24_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0492601.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            43135..43518
                     /gene="rpsK"
                     /locus_tag="VXC24_000432"
     CDS             43135..43518
                     /gene="rpsK"
                     /locus_tag="VXC24_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0492602.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43561..44496
                     /locus_tag="VXC24_000433"
     CDS             43561..44496
                     /locus_tag="VXC24_000433"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0492603.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            44508..44894
                     /gene="rplQ"
                     /locus_tag="VXC24_000434"
     CDS             44508..44894
                     /gene="rplQ"
                     /locus_tag="VXC24_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0492604.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            45159..45425
                     /locus_tag="VXC24_000435"
     CDS             45159..45425
                     /locus_tag="VXC24_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0492605.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            45435..46772
                     /locus_tag="VXC24_000436"
     CDS             45435..46772
                     /locus_tag="VXC24_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0492606.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
BASE COUNT        14169 a         8747 c        10206 g        13728 t
ORIGIN      
        1 agaaagttga aaaattttat tgaagaggaa ttcaataaat ttagaaattc tcacggagct
       61 aatctaagcc tctatgaata ctgtttgctt gataattctt taactttaaa aaatgattgg
      121 aactattctg atttagttat gaaatttacg agtaattttt atgctgatat aaaagacttg
      181 ttcatggaaa attctgatat tgaaatcatc catgaagagg gagtaccttt tgtattttta
      241 gatttaatag gtgaaggtaa aaaagaatat gaaatgtttt ttcaatggtt aaacttcttt
      301 tacaaacagc ttggaatcac attgtatgct agaaatagtt ttgggtttcg gaatctaaca
      361 gtagagtatt ttggaattat tgggacagaa agatatatat ttaagatttg tccaggtgtt
      421 tataaagggt taagttatta tttgatgaaa tttttattaa aatctttttc aaatgaatat
      481 ttaaaaacta ctgatgaggt taatagatga aaaatttgat aaagttgcta ataattagat
      541 tgattgttaa cttagcagac agtgtatttt atatagtagc attgtggcac gttagcaata
      601 attattcttc gagcatgttc ttaggaatat ttattgcagt aaattatcta ccggatttgt
      661 tactaatctt ttttggacca gttattgaca gagtaaatcc gcaaaaaatt cttataatat
      721 caattttggt tcaattagca gtggctgtaa tatttttatt attattaaac caaatatcat
      781 tttgggtgat aatgagtcta gtgtttattt cagtaatggc tagctccata agttacgtga
      841 tagaagatgt gttgattcct caagtggtag aatatgataa gattgtattt gcaaattctc
      901 tttttagtat ttcgtataaa gtattagatt ctatttttaa ttcattcgca tcatttttac
      961 aggtggcagt aggatttatt ttattggtta agatagatat aggcatattt ttacttgctc
     1021 tatttatatt gttgttgtta aaatttagaa ctagcaatgc gaatatagaa aacttctctt
     1081 tcaaatatta caagagagaa gtgttgcaag gtacaaagtt tattttaaat aataaattat
     1141 tatttaaaac cagtatttct ttaacgctta taaacttttt ttattcattt cagacagtag
     1201 ttgtaccgat tttttctatt cgatattttg atggtccgat tttttatggt atttttttaa
     1261 ctattgctgg tttgggtggt atattgggaa atatgctagc gccaatcgta ataaaatatt
     1321 taaaatcgaa tcaaattgtt ggtgtatttc tttttttgaa cggctcaagt tggttagtag
     1381 caattgttat aaaagactat actttatcac ttattttatt tttcgtttgt tttatgtcta
     1441 aaggagtctt caatattatt tttaattcgt tgtaccaaca aatacctcca catcaacttc
     1501 ttggtagggt aaatactacc attgattcta ttatttcttt tggaatgcca attggtagtt
     1561 tagttgcagg aacgcttatt gatttgaata ttgaattagt gttaattgct attagcatac
     1621 cttatttttt gttttcttat attttttata cggataatgg attgaaagaa tttagtatat
     1681 attagaaatg tttatgttca ttcaaaagca taatgactat aactgaaaaa gaaaagtgat
     1741 atctttaagg ttgttcttct tggtggtgag attcgtgaga caacccaagc ttttgtcgga
     1801 aagattacca atgctttgat ggataggatg tactttagca agatgttttt agtggtaacg
     1861 gtatcgtgga tggacgtgta ataacctctt ctttcgagga gtattttact aaaaaactag
     1921 ccttggagcg ttccccagaa acggacttac tcattgactc ttcaaagatt tggggagaag
     1981 attttgcttc atctgttcct tgaaaaaagt cacagcagtc atcacagacg atagtactga
     2041 acaaaactat gaagagttag aaatttatac gcaggtgatt gtataaagga tctggaaata
     2101 gataagaagt tgattagtat tgacctaggt ggtacaaata ttaagattac tgttctttca
     2161 aatgacggtg agattgaaac tttgtggagt attacaacag atacaagtga gaaaggttct
     2221 caaattatat cggacatcat cagttctatt aaaaataaat tgaccgaacg gaatattcct
     2281 gatagcgacc ttcttggaat cggtatggga agttgctcat catactttcc ttgtaaatca
     2341 taggggctat aaactctccg tctacttgtc ctgcaacaat tgaagtctgc tcaaaacgcc
     2401 gtccgctaat cttttcatag actttctccc ttttaggagc ctagctttct agtttgttct
     2461 ttgattttta ttgagtatac cactatttta ctccctctgg caagggactt tgtctatgtg
     2521 gagggattgg gctcctatgt ggtggagctt ttctgttctt tctgaaatat ggtataatag
     2581 cactaatcaa tttctaggaa aatagataca gaaaggggct gaaagatgtc tcatattatt
     2641 gaattgccag agatgctggc aaaccaaatc gcggctggag aggtcattga acgtcctgcc
     2701 agtgtggtca aagagttggt agaaaatgcc attgacgcgg gctctagtca gattatcatt
     2761 gagattgagg aagctggtct caagaaggtt caaatcacgg ataacggtca tggaattgcc
     2821 cacgatgagg tggagttggc cctgcgtcgc catgcgacca gtaagataaa aaatcaagca
     2881 gatctctttc ggattcggac gcttggtttt cgtggtgaag ccttgccttc tattgcgtct
     2941 gttagtgtct tgactctgtt aacggcggtg gatggtgcta gtcatggaac caagttagtc
     3001 gcgcgtgggg gtgaagttga ggaagtcatc ccagcgacta gtcctgtggg aaccaaggtt
     3061 tgtgtggagg atctcttttt caacacgcct gcccgtctca agtatatgaa gagccagcaa
     3121 gcggagttgt ctcatatcat tgatattgtc aaccgtctgg gcttggccca tcctgagatt
     3181 tcttttagct tgattagtga tggcaaggaa atgacgcgga cagcagggac tggtcaactg
     3241 cgccaagcaa tcgcaggaat ttacggtttg gtcagtgcca agaagatgat tgaaattgag
     3301 aactctgacc tagatttcga aatttcaggt tttgtgtcct tgcctgagtt gactcgggct
     3361 aaccgcaatt atatcagcct cttcatcaat ggccgttata ttaagaactt cctgctcaat
     3421 cgtgctattt tggatggttt tggaagcaag cttatggttg gacgttttcc actggctgtc
     3481 attcacatcc atatcgaccc ttatctagcg gatgtcaatg tgcatccaac taagcaagag
     3541 gtgcggattt ccaaggaaaa agaactgatg actctggttt cagaagctat tgcaaatagt
     3601 ctcaaggaac aaaccttgat tccagatgcc ttggaaaatc ttgccaaatc gaccgtgcgc
     3661 aatcgtgaga aggtggagca aactattctc ccactcaaag aaaatacgct ctactatgag
     3721 aaaactgagc cgtcaagacc tagtcaaact gaagtagctg attatcaggt agaattgact
     3781 gatgaagggc aggatttgac cctgtttgcc aaggaaacct tggaccgatt gaccaagcca
     3841 gcaaaactgc attttgcaga gagaaagcct gctaactacg accagctaga ccatccagag
     3901 ttagatcttg ctagcatcga taaggcttat gacaaactgg agcgagaaga agcatccagc
     3961 ttcccagagt tggagttttt cggacaaatg cacgggactt atctctttgc ccaagggcga
     4021 gatggacttt acatcataga tcagcacgct gctcaggaac gggtcaagta cgaggagtac
     4081 cgtgaaagca ttggcaatgt tgaccagagc cagcagcaac tcctagtgcc ctatatcttt
     4141 gaatttcctg cggatgatgc cctgcgtctc aaggaaagaa tgcctctctt agaggaagtg
     4201 ggcgtctttc tagcagagta cggagaaaat caatttattc tacgtgaaca tcctatttgg
     4261 atggcagaag aagagattga atcaggcatc tatgagatgt gcgacatgct ccttttgacc
     4321 aaggaagttt ctatcaagaa ataccgagca gagctggcta tcatgatgtc ttgcaagcga
     4381 tctatcaagg ccaatcatcg tattgatgat cattcagcta gacaactcct ctatcagctt
     4441 tctcaatgtg acaatcccta taactgtcct cacggacgtc ctgttttggt gcattttacc
     4501 aagtcggata tggaaaagat gttccgacgt attcaggaaa atcacaccag tctccgtgag
     4561 ttggggaaat attaaaagta taaaaaagtc tgggaaaaat tttcaaaatc agaaaaacgc
     4621 ataaaatcag gtgttcaaaa accttgattt tatgcgtttt atcatagaaa tatttacttc
     4681 attttttcct aattcttttc gaaactcttt ttaaacgacg tcagttttat cagtaatctc
     4741 aaaacagtgt tttgagctaa ttttgccagt tttgtctgta acatcgaagt tgtgttttac
     4801 cactctgcga ctggtttcct agtttgctct atgattttca cagagtatta aattgcgatt
     4861 ttgccaagtt tctttattcg tctaaaagta gagtctgttc tatgcgtcta atgtacgaat
     4921 taggttgacc atttcaatag ctccttgtgc acactcagaa cccttatttc ctgctttagt
     4981 gccagctcgt tctatggctt gttcaattgt atctgtcgtt agcacaccaa acataacagg
     5041 aatttcgcta tttaaactga tttgggcgat tcccttagat acctcgctac atacataatc
     5101 ataatgactt gtattccctc taatgacagc tcccaagcag ataattgcat catatttttt
     5161 actttttgcc atttttgatg caatcagtgg tatttcaaaa gctcctggaa tccaggctac
     5221 cgctatatct ttctcgttta cattctctct tttgagatta tctagtgctc cagataataa
     5281 ttttgaagtt ataaattcat taaatctcgc tacaacaata cctattttaa tattgtttgc
     5341 tactaaatta ccttcataag tgttcattta tttttcctcc atatttaaaa tgtgacccat
     5401 tcgatttttc tttgtttcta aataaaaact atcgtaagga ttggcttcta tttcgattga
     5461 tattctactg gaaatggtaa ttccatattt ttctaactgt tcaaccttgt caggattatt
     5521 tgtcagtaaa tgaagtgact gaagtcccag atctttaagc atttgtgctc caatatgata
     5581 ttctcttaaa tcaccttcaa agcctaatgc aagattggca tcaagcgtat ccatgccttg
     5641 atcttgtaaa tgataggctt ttaatttatt gataagtcca attcctcgtc cctcctgtcg
     5701 caagtaaagt aagacacccg aaccattctc aacaatcatt ttcatagctt tatcgaattg
     5761 ctgtccacaa tcgcaacgta aagagcctaa aacatcccct gttaaacatt cggagtggac
     5821 ccgacataat acattggctt catcctctat gtttcccata ataagagcaa gatgatgttc
     5881 cccatttagt ttatctatat agctaattgc tttgaaatta ccgtatctag taggcatatt
     5941 gacagttgaa actcgttcta ccagctgatc atatactttt ctatattctt gtaattcttt
     6001 gatggtaatt agtggaatgt tgtgtttctt cgagaactga attaaatcat ctgttctcat
     6061 cattttgcca tcatgattca ttatttcaca acataggcca cactctttta gtccagctaa
     6121 ttttaataaa tcaacagttg cttctgtgtg tccatttctt tctagaacac cacctttttt
     6181 tgcaattaaa ggaaacatgt gtcctggcct gcgaaaatca gagggtgtta tatcttcagc
     6241 tacacacata cgtgcggtca gtcctctttc ctcggcagaa atacctgtgg tcgtttcttt
     6301 ataatcaatt gaaactgtaa aagcagtctt atgattatct gtattgtttt caaccatagg
     6361 tgaaagcatt aattgattag ctaaactttc gctcataggc atacaaatta atcctttggc
     6421 ataagtagcc ataaaattaa cattttctgt tgtagctgct tgtgcagaac aaattaagtc
     6481 tccttcattt tctctatcct tgtcgtctat aacaagaaca agtcgtccct tctgcaatgc
     6541 ttctaatgct tcttgtattt ttcgatattc cattgactga ttatcctttc tgctaaaatc
     6601 cattttgata taatagttcc ttagatattt ctgattttgg agagttatcc atcagttttt
     6661 gcacatattt acctaagata tcattttcaa gatttactgt actcccgact tgtttactct
     6721 taagaatggt ttgttccaag gtatgaggga taacagatac tgaaaagttt actttggaga
     6781 ctttagcgac agtcagacta atgccgtcaa ttgtaataga tcctttttca actattaaat
     6841 ctaaaatttc tttttgtgtg ttgatttgat accatacagc attatcatct ttttttattg
     6901 acgagatttt tcctgtacca tcaatgtgtc ctgtaacgac gtgaccccca agtcgaccgt
     6961 tgacagataa ggctctttct agattcacct cacttccatg ttttaataga gtaagagctg
     7021 ttcgactcca tgtttcattc attacatcaa ctgtaaagga ttgatggttg aaatgagtaa
     7081 ctgtaagaca gataccattt actgctatac tatcgcctaa atggatatcc gttaatattt
     7141 ttgaggcttt aattgatagt ttacaattac gagagtcttt ctgtattctt tcaacttttc
     7201 cgatttcttc aattattcct gtgaacatgg ataaatcact tcactttcta tgagatagtc
     7261 atttcctatt tgagaaaaag cataaggttt caatctaata gcgtcatttg gcaaagaaat
     7321 gccttcacct ccgacaggaa acttggcact gcctccaaaa atttttggtg caatatatat
     7381 tttcagctca tcaacaattt gttgttccaa agcactccaa ttcattagac tgcccccttc
     7441 tagaactagg ctatcaatct gcatgtttcc tagatgttgc attaaactcg ataagtctat
     7501 atgattgcct tttttcttta tggaaagtat ttcacagcca tgattttgat atagcttcat
     7561 tttatttttg tcttcagagg aagtggcaat gtaagtttta atatcatttg ctgtttttac
     7621 gattttagag gtaagaggag ttcgtaaatg tgtatcgcat atgatacgga taggattttt
     7681 cccttcctcc aatctacatg tcagcaaagg atcgtcttga ataacagtat tgactcccac
     7741 cataattgca ctaacatagt gtcgtaactg atgcacatgc tttcttgctt cttcttcagt
     7801 aatccatttg gattgatttg ttttagtggc tatttttcca tccattgaca ttgcatattt
     7861 cataaaaaca tagggtacat gctgggtaat atactttcta aaacttttta ttaagttaag
     7921 acactcattt tctaaaattc caacagtaac ttgaagatta ttttcctcaa gtatctttac
     7981 tccttttcca gatacaatag gattacagtc taggcttcca atgactactc ttgtaatacc
     8041 actatcgatt atagcatcta tacagggagg tgttttcccg aagtgacaac agggttcaag
     8101 tgttacataa agcgtcgctc cgacagggga ttctctacag tttttaagag catttctctc
     8161 agcatgtggg ccaccaaaaa actcatgata accttgtccg atgatgtgat tatcttttac
     8221 aataactgcg ccgaccatag gattgggatt gacgtaacca gccccttttt gtgccagttt
     8281 tattgctaat ttcatatatt ttgaatcgct catctcacta cctccaaaaa aaatatacct
     8341 tgaatagggg actactcaag gcatacaaaa gaaaacttat gcgattaaca aaaatactct
     8401 gaaatgacaa gtaatcattt cagagcacgc aaaaagcaca aatatacttt tatcttcttt
     8461 catccagact atactgtcgg ctttggaatt tcaccaaatc atgcctttcg gctcgtgggc
     8521 tataccaccg gtagggaatt acaccctgcc ctgaagatag ttattcaatt acagatgatt
     8581 atagtactta attttgaata tgtcaacaga taaataccga ttgtttttga tatactgtat
     8641 ttgtgataat cgattctcgc tcctcggata aagaaaatat gatatactag ataaacgaaa
     8701 taagagagaa ggaatactat gtacgcatat ttaaaaggaa tcattaccaa aattactgcc
     8761 aaatacattg ttcttgaaac caatggtatt ggttatatcc tgcatgtggc caatccttat
     8821 gcctattcag gtcaggttaa tcaggaggct cagatttatg tgcatcaggt tgtgcgtgag
     8881 gacgcccatt tgctttatgg atttcgctca gaggatgaga aaaagctctt tcttagtctg
     8941 atttcggtct ctgggattgg tcctgtatca gctcttgcta ttatcgctgc tgatgacaat
     9001 gctggcttgg ttcaagccat tgaaaccaag aacatcacct acttgaccaa gttccctaaa
     9061 attggcaaga aaacagccca gcagatggtg ctggacttgg aaggcaaggt agtagttgca
     9121 ggagatggcc ttcctgccaa ggtcgcagtg caagcaagtg ctgaaaacca agaattggaa
     9181 gaagctatgg aagccatgtt ggctctgggc tacaaggcaa cagagctcaa gaaaatcaag
     9241 aaattctttg aaggaacgac agatacagct gagaactata tcaagtcggc ccttaaaatg
     9301 ttggtcaaat aggagcagag aatgacaaaa cgttgttcgt gggtcaagat gaccaacccg
     9361 ctctacatcg cctatcatga tgaggagtgg ggtcagcccc tccatgatga ccaagcattg
     9421 tttgagttgt tgtgtatgga aacctatcag gcaggcctgt cttgggaaac ggtactcaac
     9481 aaacgccaag ctttccgaga agcctttcat agctatcaaa ttcactcagt cgcagagatg
     9541 actgacactg aattggaagc catgctggag aatccagcta tcattcgaaa tagagccaag
     9601 atttttgcta cacgcgctaa cgcccaagcc tttctacagt tacaggcaga gtacggctct
     9661 tttgatgcct atctttggtc ttttgttgag gggaaaactg tcgttaacga tgttcctgat
     9721 tatcgccaag ccccagctaa aacaccctta tctgagaaat tagccaaaga tctcaaaaaa
     9781 cgaggcttca agttcacagg cccagtcgcc gtattgtctt ttctacaggc tgcagggcta
     9841 gttgatgacc acgagaatga ttgtgagtgg aaaggtctta aatgatgtct aacaaaaata
     9901 agggaattct gatttttgcg attctctata cagtcctctt tgtgtttgat ggcgttaaat
     9961 tgctggcttc tttaatgcca tctgccattg caacttatct tgtttatgta gttttagctt
    10021 tatatggctc cttcttgttc aaggatagat tgatccaaca atggaaggag attagaaaga
    10081 ctaaaagaaa attcttcttt ggagtcttaa caggatggct ctttctcatt ctgatgactg
    10141 ttgtctttga atttgtatca gagatgttga agcagtttgt gggactagat ggacaaggtc
    10201 taaatcagtc taatattcaa agtacctttc aagaacaacc actactgata gctgtttttg
    10261 cttgtgtcat tggacctctg gtagaagaat tatttttccg tcaggtctta ttgcattact
    10321 tgcaggaacg gttgccaggt ttactaagca ttattctggt aggacttgtt tttgctctga
    10381 ctcatatgca cagtttggct ctatcagagt ggattggtgc agttgattac ttaggtggag
    10441 gccttgcctt ttctattatt tatgtgaaag aaaaagagaa tatctactat cccctacttg
    10501 ttcacatgtt aagcaacagc ctctccttaa tcattttagc tatcagtata gtaaaatgaa
    10561 ataagaacag gacaaatcaa tcaggacagt caaatcgatt tctaacaatg ttttagaagt
    10621 agaggtgtac tattctagtt tcaatacact gtaacatgtg atgaaaatgc cagtaatgat
    10681 accgagaaaa aagctgagaa acttttccca gctttatttg ttatagtcaa agcgaatgac
    10741 ttgttcctgt gcatctacat gagcatggac cccaaagggt acaattgctc ttggagttgc
    10801 gtggccgaca ttcagattat agacaatcgg gatattgttg tcaatgatat ccaatagtgc
    10861 ctctttatag tcgtcatgga aagtttcatc cataggtttt ccgaccaaga gtccattgat
    10921 gaccgcgaat atgccagtgt cctttaaagt tagcaacatc tttttgaagt cttctggctt
    10981 aggctcttct tcgcttgttt cgagcaagag gattttccct tcccagtctg acaagtcagg
    11041 gaaaagtttg tatttttggc agagttccgt gctatctgcg tatcgagagt tgtcaaagat
    11101 atcgtagagg gattcgaggc aaccaccgag gattttcccc tcgaactgag cacttccttg
    11161 caacaagtca aaacctgtat ttgtatgact gacacgaggt gttcccaggg ccgtgggact
    11221 aaaatcagtt cgttcctcat accaaacgtc actagggcgg atttctgaaa ttcttcccgt
    11281 ctcaatcaat tctttaaagt agtgaaggct ataggctagc atttctttgt ctaattcaca
    11341 aatgtctgct aaaaaggatt gaccataaaa agtcttgatt cctaatttat gcaacatgag
    11401 gtggttcatg gttgtatccg agaagccaag aaaaattttt tgtttgataa ccttttggag
    11461 ttggtcattt tcaaaaagat aaggtagcaa gcgataggta tcgtctccac ctatggcaca
    11521 taggatcatg tcgatgctat catcagaaaa ggcatgaatc aaatcctctg cacgagcttc
    11581 aggatggtcc ttgataaagt ctaatccttt taacgaatgg ggcaaaaaga tgggattgag
    11641 tcccagaacc ttgagacgtt ggatacccaa gtccacttcg tgtttgacaa aatcctctcc
    11701 gataatgcca ctagataaac taacaatacc aatagtagaa accatatctc atcctcctag
    11761 aaatagattg agcctatttt atcacaaaat ataagagaaa gctatgtggg atttcagaag
    11821 aatactttta atactcttcg aaaatctctt caaaccacgt cagttttatc tgcaacctca
    11881 aagctgtgct ttgagcaacc tgcagctagc ttcctagttt gctctttgat tttcattgag
    11941 tataactcaa aaaagtaagt gaaaaagcaa ccgcacctgc agttgctttt atcgttttct
    12001 tattcttgat agcgtgttgg tcctgcactt gcactacgga tattcaagcg tttcttgaga
    12061 tagaagcgaa gggctaggag agctgctcca ataatagcta gtggcaatgg atccagtact
    12121 gggttaaggc tagctggtag gaagcttgtt gcaaagaaga caagcaacca aaggaacata
    12181 gaagctagga taactagtac agatttccag aaaggtggac gttgactgcg atccatatct
    12241 ggtccatagt attggtaaac aaagtagtac atcaagtaga aggcaaatcc accaaccagt
    12301 ccaactaata gaagagtaat caatccatag ccgaaagctt gatctgccgc aaagaaggtt
    12361 gtgagggcgc tgacaagggc aaagaggcta gtgatgaaaa gagctgagtc cataatcatc
    12421 agttttgggt catcattttc ttttggatgc tctttttcgt actgctcttt gacagtgaag
    12481 ctatgagccc aatgagttgg tgcgccgtat agggaacggg cagttgtacc tttagattgc
    12541 tcctcaagga tttggggaat gacttcctca aaaatagtct ggatttcagc gtctgttttc
    12601 ccatctttga tgaattgttg ggtagcaatg tggacaaact cttggttttt cttagttaat
    12661 ttttgtagat caatttgaga cataggaact cctcttagaa ccatttttta tggatgagat
    12721 agagagtgag cgagacactc atagcaaagg cgataaagac gattaaccag aaggcatttg
    12781 gctctccgtt taggggaatt tcattatcct taaagttcat cccgtaggca gaaaagacca
    12841 tggttgggat ggacatgacg atggtcacaa gggccaaggt tttcatgatg ttgttctggt
    12901 tgttagaaat gatagaggca aaggtctctg tcatagaatg caagacgttt ccataaatat
    12961 ctgccatctc gatggcctgt tgggtttcaa tcagggtgtc ttcaagcagg tcttcgtcct
    13021 caaggtattt cttgatattg ctggttgaac tggtcaattt cttaatcacg cgctcatttg
    13081 ttttgaggga ggccttgaaa tagacgatag ttttttccaa ttccatgagc tcaatcaatt
    13141 cttcattacg agttgattga tgcagttgac tttcgatttg ttcactcttg cggtcgattg
    13201 aacgaagggc tgttaggtaa agctctgcat tgcgataaag aatttgaaag ataaaacgtg
    13261 aacgcatgaa ggtatagaaa ttacgcaatc gacggttgat aaagacatca aggacaggta
    13321 gtggttccaa acacgtagtg ataatggttt cctcagtgat gataatacca agcgggatgg
    13381 ttacgtagta ggtgcggtta tttctttcct ccgtgaccgg cacgtctacg ataatcaggg
    13441 tatactcgtc ttcaatggta atacgagaca tttcttccgc atcgagcggt gctcgaaggt
    13501 cggcaatatc aatatcgaag gtgttggcga tttcgagtga ttcattttga gtcggattga
    13561 cgagattgat ccaagtaccc ggttcaagcg tatcgatctc tttaaattca gttgttgtag
    13621 agagaaaaac ttgtttcata tcccttatcc tttctcattt ttcagatttt ttcacactgt
    13681 actattatac tacaaaatcg gccttttggg taatagaatc tcactttttt tggtataatg
    13741 gtaagcaata atggactaga aagaacaaag atgcaagata aaattgtcat tcatggggcg
    13801 cgtgcccata atttaaaaaa tattgatgtg gagattccgc gagacaagtt ggttgtcgtg
    13861 actggcttgt caggttcagg gaagtccagt ctggcttttg atactctcta tgcggaggga
    13921 caacgtcgct atgtagagag tttgtctgcc tacgctcgtc agttcttggg aaatatggaa
    13981 aaaccagatg tagatgccat tgatggtctc agcccagcta tttccatcga ccagaaaacg
    14041 actagtaaaa atcctcgctc gacggtggga acgacgactg aaatcaatga ctatctgcgt
    14101 ctcctctacg cacgtgtggg gacgccttac tgtatcaacg gacatggagc tatcaatgct
    14161 tcttctgtgg agcaaatcgt tgataaggtt ttggagttac ctgaacgcca gcgcttgcag
    14221 atcttggctc ctgtcatccg caagaaaaaa ggccaacata agagtgttat cgagaaggtt
    14281 cagaaagacg ggtatgttcg tgttcgtgtg gatggggaag tctatgatgt gaccgaagtg
    14341 ccagagttgt ctaagagcaa gcaacacaat atcgatgtcg tggttgaccg tattgttatc
    14401 aaggagggca ttcgtagccg tctctttgat tccattgaag ctgcccttcg tatcgcagaa
    14461 ggttatgtga ttatcgacac catggacgac tctgagttgt tgttctctga gcattatgcc
    14521 tgtccagttt gtggatttac tgtcccagag ttagaacctc gtctcttctc tttcaatgct
    14581 ccctttggct cttgtagtga gtgtgacggc ttggggatca agctggaggt agatactgat
    14641 ttggtagtgc cagatgccag caaaacctta cgtgagggag cgctagcacc ttggaatcct
    14701 atctcatcca actactatcc aaacatgtta gagcaggcca tgaaagtctt tggagtggct
    14761 atggataagc cttttgagga cctgtcagaa gaagataaga acttgattct ctatgggtca
    14821 gatggtaagg aattccattt ccactatgag aatgaatttg gtggcgtgcg cgatatcgac
    14881 attccgtttg agggagttat caataatatc aaacgtcgtt accatgaaac caatagcgat
    14941 tacactcgca ctcagatgcg tctctacatg aatgagctga cctgcggaac ctgtcaaggc
    15001 tatcgtctca atgaccaggc cttgtctgtc cgtgtgggcg gccagcaagg gccacatatt
    15061 ggagaaatct cagacctgtc tatcgctgac cacttggact tggtgagcca gttaactttg
    15121 tctgaaaatg aagccatcat tgctcgtccc attctcaagg aaatcaagga tcgtttgacc
    15181 ttccttaata atgtgggtct taactatcta accctgtcac gttcagcagg aaccctttca
    15241 ggtggggaaa gtcagcgcat tcgtttggca acccagattg gttccaacct atcaggcgtc
    15301 ctctatatcc tagacgagcc gtcaatcggt cttcaccaga gggacaatga ccgcctgatt
    15361 gccagtctga aaaagatgcg tgacttgggc aatactctta tcgtggtgga acacgacgaa
    15421 gataccatgc gtgaagctga ttatctgatt gacgttggtc ctggtgccgg tgtttttggt
    15481 ggtgagattg ttgcagcagg tacacctaag caagtggctc gcaacagcaa gtctatcaca
    15541 ggtcagtact tgtcaggcaa acgtgtcatc ccagtaccag aagagcgccg tgtcggaaat
    15601 ggtcgtttta ttgaagtgac aggagcgcgt gagaacaact tgcaaaatgt cacggctcgc
    15661 tttccactag gaaaatttat cgcagtgaca ggtgtgtcgg gttcagggaa atcgactcta
    15721 atcaacagca ttctcaaaaa agccattgcc cagaagctca accgtaattc agacaaacct
    15781 ggtaagttta agactattac agggattgag catgtcgacc gtttgattga tattgaccag
    15841 agccctatcg gacggacgcc gaggtctaac ccagctacct atacaggagt ttttgacgat
    15901 atacgtgacc tttttgctca gacaaatgaa gccaagattc gaggctacaa gaaggggcgc
    15961 ttcagtttca acgtcaaggg aggtcgctgt gaagcttgct caggtgacgg gattatcaag
    16021 attgagatgc acttcttgcc agatgtttat gtggcttgtg aagtttgcca cggaacccgc
    16081 tataacagtg aaaccctaga agttcactac aaggaaaaga atatttcgca ggtcttggat
    16141 atgacggtca acgatgcggt agaatttttc caacacattc cgaaaattca acgcaaactc
    16201 cagaccatca aggatgtagg gctaggctat gtgaccttgg gacagccagc taccaccctt
    16261 tctgggggag aagcccaacg tatgaagtta gctagcgaac tccacaaacg ctcgacagga
    16321 aaatctttct acattctgga tgagccgacg acagggcttc atacagagga cattgctcgc
    16381 ctgctcaagg ttttagctcg ctttgtagac gatggcaata cagtcctcgt catcgagcac
    16441 aatctggatg ttatcaagac ggcagaccat atcattgact tgggacctga gggcggtgtc
    16501 ggtggtggaa ccatcatcgt aacaggaact ccagaagaag tagctgccaa cgaagccagc
    16561 tatacaggac actatttgaa aggaaagtta catcatgaat aaacgcgtac aagcatttct
    16621 agctaaaatg caagaaaaag aactagatgg tatcatcatc aacaatctta aaaacgtcta
    16681 ttatttgact ggtttttggg gctcaaacgg aacagtcttt atcagtcgtg accgtcaggt
    16741 cttagtgaca gactctcgct atatcatcgc agctaagcaa gaaaccagtg gttttgagat
    16801 tgtggctgat cgtgatgaat tggctgtcat tgcaggaatt gttaaggaca tgggcttgac
    16861 tcgtatcggt tttgaagatg agatttcagt gtcttattac caccgtatgc aggcagcttt
    16921 tgcaggtttg gacttgtttc cgcaaactca gtttgtggaa ggtcttcgta tgattaagga
    16981 tgaggcagag attgcagcga ttcgcaaggc ttgttctatc tcagaccaag ctttccgcga
    17041 tgcgcttgac tttatcaaac caggaaaaac tgaaattgag attgccaact tccttgactt
    17101 ccgcatgcgt gagttgggag catctggctt atcttttgat acgatcctag ctagcggtat
    17161 caattcttct aaaccccatg cccatccaat gcacaaacca gtggagttgg gagaagccat
    17221 taccatggac ttcggctgtc tctatgacca ctatgtcagt gatatgaccc ggactatcta
    17281 tctagggcat gttagcgatg agcaggcaga gatttacaat acggttctaa aagctaacca
    17341 agccttgatt gaccaagcta aggcaggctt aggtttccgt gactttgaca aaatccctcg
    17401 tgatattatc attgaggcag gttatggcga ctactttact cacggcattg gccacggtat
    17461 tggtctggat atccatgagg aaccctactt tagccagact tctacagaaa ctattaagac
    17521 aggtatggcc ttgaccgatg aaccaggtat ctatatcgaa ggcaaatatg gcgttcgtat
    17581 cgaggatgat atcctgatta cagagacagg ttgtgaatta ttgaccctag ctccaaaaga
    17641 gttgatagtc atttagttgt ttgtcaagaa aaaagtacga aaatgacgaa aaaagtcaaa
    17701 aaaaattaaa aataggtcgc aagtcggatg ttttttatgg tataatagac taaactgata
    17761 gtaacatgta gcgaaagggg taggtacatg attaaaattt atacagtctc aagttgtact
    17821 agctgtaaaa aagcaaaaac ctggctcaat gcccaccagt taagttataa agaacaaaac
    17881 cttggtaaag aaggaattac gagagaagaa ttactggata ttctaaccaa aacagataac
    17941 ggaatagcca gcatcgtttc gtctaaaaat cgctatgcca aagcccttgg agtggatatt
    18001 gaagatttga gtgtcaatga agttctcaat ctgattatgg aaacaccgag aattttaaag
    18061 agcccaatcc ttgtagatga aaaacgcctg caagttggct acaaggaaga cgatattcgt
    18121 gccttcctac cacgctctgt ccgtaatgta gaaaatgcag aagcacgttt acgtgcagct
    18181 ctataaacat caaggctggg agcaattccc agtcttattc tattttaatt tcaaaaagaa
    18241 agaagaaaga aatgaaaaaa atagttcttg ttagtctagc tttccttttt gtcctggttg
    18301 gttgcggaca gaaaaaagaa actggaccag ctacaaaaac agaaaaggat acgcttcagt
    18361 cggcattgcc agttattgaa aatgccgaga agaatacagt tgtaaccaag actttggtct
    18421 tgcccaagtc agatgatggt agccagcaaa ctcaaaccat tacatacaag gacaagactt
    18481 ttttgagctt aacgattcaa caaaaacgtc cagtttctga tgagttgaag acttatattg
    18541 accaacatgg agtggaagaa actcaaaaag ctcttcttga agcggaggag aaggataagt
    18601 ctatcattga agctcgtaaa ttggtaggtt tcaaacttga aacaaaacta ttgagcgcaa
    18661 cggaacttca aacaacgact agttttgatt ttcaagttct ggatgtcaag aaggcttccc
    18721 agttggaaca tctgaagaat attggtttgg aaaatctttt gaaaaatgaa ccaagcaaat
    18781 atatttcaga cagattggca aatggtgcga cagaacagta gaaaatccaa ataaatagac
    18841 tgcctgaatt gtagaaggta aggaattatg ctataatggt actattctaa ggaaagaggg
    18901 tgttagaatg ggatttactg aagaaacagt acgttttaaa ttggacgatt ccaataaaaa
    18961 agaaattagc gaaactttga cagatgttta tgcttcgttg aacgataagg gttacaaccc
    19021 aattaaccaa atcgtaggtt acgtattgag tggagaccct gcctacgttc ctcgttataa
    19081 taatgcacga aatcaaatcc gtaagtatga gcgtgatgaa atcgttgagg aattggttcg
    19141 ctactacctc aaaggacaag gagtcgatct ataacctatg agaattatgg gattggacgt
    19201 cggttcaaaa acggtagggg tggcgattag cgatccgctt ggttttacag ctcaagggct
    19261 tgaaatcatc cagataaatg aagaacaagg ccaatttggt tttgaccgcg ttaaggaatt
    19321 ggttgatact tacaaggtgg aacgatttgt agtgggcttg cctaaaaaca tgaacaatac
    19381 aagtggaccg cgcgtagaag ctagtcaagc ctacggagca aagctagaag agttttttgg
    19441 tttaccagta gactatcagg atgaacgctt gacaacagtg gctgctgagc gcatgttgat
    19501 tgaacaagca gatatcagtc gcaataagcg caagaaagtc attgataagt tagcagctca
    19561 gctgatttta caaaattatt tagatagaaa attttaatat aaaggagagg ctatgtcaca
    19621 cgatcataac cacgaccacg aagaacgtga actaatcaca ctagtagatg agcaaggaaa
    19681 tgaaaccttg tttgaaatcc ttttgacaat tgatggaaaa gaagaatttg gtaaaaacta
    19741 tgttcttcta gtaccagtta acgcagaaga agacgaagac ggacaagttg aaatccaagc
    19801 ttactcattc atcgaaaacg aagatggaac agaaggcgaa ttgcaaccaa tcccagaaga
    19861 ctcagaagac gaatggaaca tgattgaaga agtcttcaac agctttatgg aggagtgata
    19921 cagtctggga gactgtatca gcccaactcc cagaaatggg gaagagttgg aacgtccagt
    19981 ggatgttttt agcccagttc ctttaaataa gagagaactg gtaggttcgg ggggacgttt
    20041 ttagcccagc tcctttaaat aagatagagc tggtaagtct gggagactgt atcagcccaa
    20101 ctcccagaaa tggggaagag ttggaacgtc cagtgaacat ttttacccca actcttagaa
    20161 attgagaaga gttggaacat ctagtggatg tttttagccc atattcacat tcatagtggc
    20221 tagttattag ctaaccaggt aagaggtcgg gacgaaaatc ctggccttgt ttttattagt
    20281 aaccatactt taatgcgata attgattgga cttttgtcaa ggagatgtgt atgtttgaag
    20341 tagaagaatg gctccatagt cggattggtt taaattttcg atcaggtttg ggccgaatgc
    20401 agcaagcggt ggatttgtta ggaaatcctg agcagtctta ccctattatc cacgtaacag
    20461 ggactaatgg gaaaggatct accattgctt ttatgaggga attatttatg gggcatggca
    20521 aaaaagttgc gacctttacc tcccctcata tcgtctctat caatgaccga atctgcatta
    20581 atgggcaacc tatagcagac gcagacttta tccgtttggc tgatcaggtc aaggagatgg
    20641 agaaaacgct tctgcaaact cctgaccagt tgtccttttt tgaattgctg accttggttg
    20701 cttttcttta ttttagggag caagaggtgg atttggtttt attagaagtg ggaattggtg
    20761 gcttacttga cacgaccaat gtggtaactg gagagcttgc tgtcatcacc tccattgggc
    20821 ttgaccatca agaaaccttg ggtgatagtc tagaagcaat tgcagagcag aaagctggta
    20881 ttttcaaggc tggtaagaag gcagtgattg cgaaattgcc tccagaagct aggcttgtct
    20941 gtcagaaaaa agccgaatct ttagctgtta acctttatca ggcaggtcaa gattttttaa
    21001 tgctgaatgg tgatttttca agctctttac taaatctttc acagctgaac ataggcttag
    21061 aaggagtcta tcagcaggag aatgcagcct tggcgttgca aacttttctt ctttttatgg
    21121 gagaaggaaa ggaagctgtt gatgaacagg ctgtaagaaa ggccttggaa cagacccatt
    21181 gggctggtcg cttggagcgt attcgcccac agatttactt ggatggtgct cataacctcc
    21241 ctgccttgac tcgcttggtt gagtttatca aagaaaaaga gcaggaaggc tatcgacctc
    21301 aaatcctttt tggagccttg aaacggaagg attatcaagg gatgttaggt tacctgactg
    21361 aaaaattgcc tcaggtggaa ctcaaggtga ccggctttga ctatcagggg gctttggacg
    21421 aaagggatgt gacaggttac gatatagttt cttcttgccg agaatttatc agcgattttg
    21481 aagaaagagc agatgctcag gatttgctgt tcgttacagg gtctctctat tttatctcag
    21541 aagtacgggg ctacctgctg gaccgtgagc agataaattg acccccttgt ttgaacttgt
    21601 tatactaggg gaattgctgg ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt
    21661 catcatgaaa ttaaaaagat tcacactttc tcttgcttct ctagcaagtt ttagtctctt
    21721 agtagcttgt tcacaaagag ctcaacaggt tcaacagcct gttgctcagc agcaggtcca
    21781 acagcctgct caacaacctg ctcaacagaa taccaatact gcaaatgcag gaggtaacca
    21841 aaatcaagcg gctccagtac aaaaccaacc tgttgctcaa ccgaccgata ttgatgggac
    21901 ttatactggt caggatgacg gagaccgtat cactttagtg gtaactggaa cgactggtac
    21961 atggactgag ctcgaatctg acggggatca gaaagtcaaa caggttacat ttgattcagc
    22021 aaatcaacgc atgattattg gcgatgatgt caaaatttac actgtaaacg gtaatcaaat
    22081 cgtcgtagat gatatggata gagacccatc ggaccaaatc gttttaacta aataagacta
    22141 tgcaagtaga aagggctgga tttttcagcc tttttacttt tacctagaaa ataatcataa
    22201 atacttgcct tctaccgaat acctgcgtta tactagtatc aattacttgt ttttagcatt
    22261 caaactatca aggaggggat atgaaatata ggaaatttca attattgatg tccaagtatg
    22321 gctttagtct ttcgattatg ttacttgaac tttgtcttgt ttttggtctc tttctttatt
    22381 taggacgcat ggctcccatt ttatggatta ctgtcctcat tctactgagt atcatcacaa
    22441 tcatttcgat agtcaaccgt aatacgactc ctgagaataa ggtaacctgg ttgttagtag
    22501 cctttgtgcc agtatttggt cccttgctct atctgatgtt tggtgaaagg cgattgtcca
    22561 aaaaagaaat caaacaactg aagaagctag gctctatgca tttccaagaa gcaaatagcc
    22621 agctactaaa agagaaatta aaagaaagtg acaaggcagc ttatggagtc atcaagtcct
    22681 tattgagtat ggataccaat gctgacatct atgatcaaac tgcctctaca ttttttccta
    22741 acggagaagc tatgtggaaa aagatggtag aagatcttaa aaaggctgag aaatttattt
    22801 tcttggaata ttacattata gaagaaggtt tgatgtggaa tcgcatacta gatatactag
    22861 agcaaaaggt agctcagggt gtagaggtta agatgctcta tgatgatatc ggctgtatgg
    22921 ctactttaac aggagattat gcacatcgac ttcgtcagct gggcatcgag gcccataaat
    22981 tcaataaagt tattcctcgt ttgacagtgg cttataataa cagagatcat agaaaaatat
    23041 tgattgttga tggtcagata gcctatactg gtgggatcaa tctggcagat gagtacatta
    23101 accacgtcga gagatttggt tattggaagg atagtggaat tcgcttagac ggactagcag
    23161 taaaagctct gacacgctta tttttgacca cttggtacat taatcgagga gaaattagtg
    23221 attttgatca atatcattta gaaaatcatt ctatcccgag tgacggttta accattccat
    23281 acggaagtgg acccaagcca atttttcgag cgcaggtagg gaaaaaagtt tatcagagtt
    23341 taatcaatca agcaacagaa tcggtctata ttacgacacc ttatttgatt atagattatg
    23401 atttaacaga gacaatcaaa aatgcagcta tgagaggggt cgatgttcga attatcaccc
    23461 cttacatacc agataagaag ttcattcagt tagtcacgag aggagcttat cccgaccttc
    23521 tttctgctgg tgttcggatt tatgagtata gtccaggttt tattcatagt aagcagatgt
    23581 tggtagacga agattttgcg gtggtgggga caatcaatct cgactaccgg agcttggtac
    23641 accattatga aaatgcagtc ttactctata aaactccttc tataagggaa atcgcccgag
    23701 attttcgaaa tatatttgca gattctcagg aagtctatcc tcattctatc aaaacgagct
    23761 ggtatcaaaa gcttgtaaaa gaaatcgccc agctattcgc ccctatctta taagaaatct
    23821 agaacttagg atacaaacca gacctatttt tcttgtcttt tacgaataga aagaaagagg
    23881 aggggaattc atgctaacta aggaagaagt gaatgatatg attgagttca aacagacaca
    23941 tttacaccgc tttcgggaaa ttgaaacctt tgtgaaacta tgcaaaaaat cactcaaaca
    24001 gccatcgcaa gctgacaatc ctaggacttt ttgatatact aagacagata aattgaacag
    24061 gagaaacgat atgagtgtgt atggtagagt agaagaagtt cataaggaga atcgtgaacc
    24121 tctagaatac caaatcgaac aagaatcgca tcatcgtgaa tcaagtcgtc ttcctttggt
    24181 gaaaatttta ctatggagta cgcttgtaac ggggataact ctaggagtac cgctattact
    24241 cgacttaatg agtgcacaag aagtgcagga tttttatgca ggttgggcgc ttcatcagac
    24301 agggaagatt tacagcgact attatggaag tcaaggtttg ctttattatt tgctgactta
    24361 cgtgagtcag ggcggatttt tctttgccat ctttgagtgg ttagccttgg tagcaggagg
    24421 atttttcctt tttagatcag cggacacctt gacagagcaa ggagaccaag ctggacatct
    24481 ggtgactatt ttttacatgc tagttacagg tcttgctttt ggtggaggct atgcgactct
    24541 tttagcgctt cctttcttat tcgcagcctt tagtttagtt gcggcttacc taagcaatcc
    24601 aagccatgat aagggatttg tacggattgg gctagctttg gcaggcggat ttttctttgc
    24661 tcccttatca tcgctcctgt ttattgctgt agtgagttta ggcttgttgg tctttaacct
    24721 tgggcataga cgctttgcgc atgggtttta tcagtttctt gcagtggctt taggtttttc
    24781 acttgtcttt tatccaactg cctactatag tgctgcaaca ggaagttttg gggatgcgat
    24841 tagtggtatt cgttatccta ttgacagtat tcgctttgat tttacttcta aaattttaga
    24901 gaatatgttt ttttatggct tgttgtccct tggtttggga tttgtggttt gtatcttttt
    24961 aggtctcttt caatccaaac cctttaaact atacgtcatt tcggttcctg caagtcttgt
    25021 ggtaatttta ggtttgattt tacttttctt ttcacaagag cctctgcacg cttcttattt
    25081 gatggtcgtc ttccctgttt tcctactttt attggtaacc aatattaaga gtcaacagag
    25141 ggggcgtagt gctagaagaa gccgaagaga aacgccagtt agcctatgga gtcgtttctt
    25201 caaaggaaat ctatatctgc tagtttttga gtttgtctat cttttgtctg ttcctttttt
    25261 gatgaagttt gtcctttatc cagtacctta tcaagaacgt aatcgtcttg ctgatttggt
    25321 aaaagaggag acaaatacgg aagatgctat ctatgcatgg gatgatactg cgactcttta
    25381 tcgtaagagt gagcgcttgt cgccatcggc gattttgtcc ccgttgcact atacagcaac
    25441 tgaggaaaat cgtaataagt tacttaatga cttgaaagaa aaacaaccta aggtgattgt
    25501 ggtaaatgat aaggtggtag tctggtctga agtggaaaca ctcttaaaag aaaattacca
    25561 acaagtaaag actgattact cagagtttaa agtctataaa attaaataac caaatcaata
    25621 tcttgtgtat ttttaaaaat tttaggattt ttaacacaag atattgattt ttctttttag
    25681 agtggtataa tactttttag aaagaacatt ttagaaaaga gcatgcatat gattgcacta
    25741 gaagaaaaaa ttacaatttt gccaactctc ttcgtcgaga aacgagatgg gagacgtgtt
    25801 gtatttgatg tggacaagat tgacaaggct ctccacaagg cggctgacaa ggttatggat
    25861 gtgacacccc tggttgaaaa acgcctcaat gatctgactg agcgaattat tacagaaatt
    25921 catagtcgct ttccacaggg aattaagatt tacgaaattc aaaatatcgt agaacatgaa
    25981 ctccttgaag ccaaagaata tgcgctggct gaggagtata ttacttatcg gacacagagg
    26041 gattttgagc gctcaaaagc gacggatatc aactttagta ttcataaact tctcaacaaa
    26101 gaccagacag ttgtcaatga aaacgctaat aaagacagtg atgtctttaa cactcagcgt
    26161 gatttgacag cagggattgt tgggaaatca atcggactgc aaatgcttcc taagcacgta
    26221 gccaatgccc accaaaaggg ggatatccac tatcacgatt tggactacag tccctatacc
    26281 cctatgacca actgctgttt gattgatttt aagggtatgt tggaaaatgg ttttaagatt
    26341 ggaaatgcag aggtagagag tcccaagtct atccagactg cgacagcaca gatttctcaa
    26401 atcattgcca acgttgcttc tagccagtac ggtggctgtt cagctgaccg tatcgatgaa
    26461 attttggcgc cttatgcaga gaagaattat caaaaacatc tcaaagatgc agaagagtgg
    26521 gtattgcctg aaaaacggga agattacgct tggaagaaaa cgcaaaagga catctacgat
    26581 gccatgcaat ctcttgagta tgaaatcaat actctcttca cttcaaatgg acaaacacct
    26641 tttacttcgt taggttttgg tctgggaacc agtcgttttg aacgagaaat tcaaaaagct
    26701 attttaaaca ttcgcatcaa gggtcttggt tcagaacacc gtacggctat ctttcctaaa
    26761 cttattttca ctctgaaaag aggccttaat ttagaggaag gaactcccaa ctacgacatc
    26821 aagcagttgg ctcttgagtg tgcaaccaaa cggatgtatc cagatgtttt atcttacgat
    26881 aagattgttg acttgacagg atccttcaag gtgcctatgg gttgccgttc tttcctccaa
    26941 ggatggaagg atgaaaatgg tgtagaagtc aattcaggtc gcatgaatct gggtgttgtg
    27001 acggttaatc tgcctcgtat tgctcttgag tctgaaggtg atatgaataa gttctgggaa
    27061 atcttcaacg agcgaatgaa tatcgcagaa gatgctcttg tttaccgtgt cgaacgcact
    27121 aaagaggcga caccagcaaa tgctcctatt ctttatcagt acggtgcttt tggccatcgt
    27181 ctaggtaaag aagaaagtgt tgaccagctc tttaagaatc gtcgtgctac cgtttcgctg
    27241 ggctatatcg gcttgtatga agtagcgaca gttttctttg gtaacagctg ggaaagtaat
    27301 ccagatgcta aggaattcac gctagacatc attcacgata tgaaacgccg tgtagaagag
    27361 tggtcagacc aatatggcta ccatttctct atctactcaa caccatccga aagtctgaca
    27421 gaccgtttct gccgactaga tatagacaag tttggctcta ttcctgatat cacagacaag
    27481 gaatactaca ccaactcttt ccactacgat gttcgtaaaa atccaacacc gtttgaaaaa
    27541 ttggactttg agaaagtcta tccagaagca ggtgcgtcag gtggtttcat ccattattgt
    27601 gagtatccag tccttcagca aaatccaaag gccttggaag ctgtctggga ttatgcttat
    27661 gaccgtgtag gctatctagg caccaatact ccgattgacc gttgctacaa gtgtgacttt
    27721 gaaggggatt ttgaaccaac tgagagaggg tttgcttgtc caaactgtgg caatagcgac
    27781 cctaaaacag tagatgtggt gaagcgaact tgtggctacc taggtaatcc tcaagcaaga
    27841 ccgatggtca acgggcgtca caaggaaatc gctgcgcgtg tcaaacatat gaatggttca
    27901 acgattaaaa tagctgggca tcaagtaaca aattagaaag aaatgaaatg ggaaaatatc
    27961 aactagacga taaggggcgc gcacaagtga cccgttatca cgagaaacac tctaaaggtg
    28021 gagctggtaa gaaagaacgc ttgcttagct tcagagaaca atttttaaac aagaacaaga
    28081 aaaaataaaa gtgagagcca gctctcgctt ttctcatagt gggaggtaag gatggaatta
    28141 cgcagaccaa gattagcgga taagaaagct gttttagata tgatgacaga gtttgaaaag
    28201 agtcaatcag cccatgatgg aggattttgg gatgttgagg atttttctta cgaggagtgg
    28261 ctagaaggta accgtaataa agaaatggga atatggctac ctgaaaatcg cgttccatcg
    28321 atacagttcg tattgtttgg tgaatcaggt tgtgctctag gatttttgaa tctgcgattg
    28381 agactgaatg aggggttact gaattatgct ggccacattg gctactccat ccgtccatct
    28441 gaaagaggca agggttatgc aaaagagact ctccgtcagg gcttgcaagt tgctaaggaa
    28501 aagaacatca agaaagctct ggtgacctgt agcgtgaata atcttgctag cagagcagtc
    28561 attctagcaa atggtggaat atttgaggat gctcgcaatg gagtcgagcg ttattggata
    28621 gaggtagcga atgaataatc caaaaccaca agaatggaaa agcgaggaac ttagtcaagg
    28681 tcgtatcatt gactacaagg cctttaactt tgtggacggc gaaggcgtgc gtaactctct
    28741 ctatgtatca ggctgtatgt ttcactgcga gggatgttat aatgttgcga cttggtcttt
    28801 taatgctggc attccctata cagcagaatt agaagagcag atcatggcag atcttgctca
    28861 gccctatgtt caaggtttga ctttgttggg aggggagcct tttcttaata ctgggattct
    28921 cttgccactt gttaagcgga ttcggaagga attgccagac aaggacatct ggtcctggac
    28981 cggctacact tgggaagaaa tgatgttgga aactccagat aaactggaat tcttgtcact
    29041 gattgacatt cttgtcgatg gaagatatga tcgaactaag agaaatctta tgctccagtt
    29101 tcgaggttcg tctaaccaac gaattatcga tgtgcaaaaa tcgctcaaaa gtgggcaagt
    29161 agtgatttgg gacaagctca atgacggaaa agaaagctat gaacaggtga agagagaatg
    29221 aagaaaaaag acttagtaga ccaactagtc tcagagatcg agacggggaa agtcaggaca
    29281 ctgggaatat acggtcatgg agcttcaggt aaatcaacct ttgcacagga attgtaccaa
    29341 gctttagatt ctactacagt aaatttgcta gagacagatc cttatatcac ctcaggacgc
    29401 catctggtag tacccaagga cgcgccgaat caaaaggtga cagccagtct gccagtggcg
    29461 catgaactgg agagtttgca gagagatatc cttgccttgc aggcgagtat ggatgtcttg
    29521 acaattgaag aaccttggaa ggctagtgag gtcttgtctg gagccaaacc aattttgatt
    29581 gtcgaaggga tgtctgttgg ctttctaccc aaggaactct ttgaaaaaac catctgtttc
    29641 tacacggatg aggagaccga attaaagcga cgccttgcta gagatacgac tgtgagaaat
    29701 cgcgatgcat cctttatatt ggctagccat cagatgagac gggagcagta tctgcgatac
    29761 tataaagaaa ctgagtctaa ggcggatatc ttagtggacc aatcagaaga taaatttgat
    29821 gtcaagagga cttaacttat gtatagaaga aatatagaag aaaatcccta attttagaaa
    29881 gaaaaagtag gaaaacagtt tcatccccaa aaaacgaaaa aacctaacaa atcccttgca
    29941 atcgcagggg atttgtgtta ttctattatg gtgctgtaaa ttacagcctt agttttgatg
    30001 caagaggttg cgacacgctc ggttgcattg ccacgcaaca ccgcgtcggt tttcttgtgg
    30061 agctagccta ttatcttaaa tagacgaaaa ggagaaaaag atggcaaaca aaaaaatccg
    30121 tatccgtttg aaagcttacg aacaccgtac gcttgacaca gcggctgcaa aaatcgtaga
    30181 atcagctact cgtacaggtg cacaagttgc gggtccaatc ccacttccaa ctgaacgtag
    30241 cctctacaca atcattcgtg cgactcacaa atacaaagac tctcgcgaac aatttgaaat
    30301 gcgtacacac aaacgtttga tcgatatcgt taacccaact caaaaaacag ttgatgcctt
    30361 gatgaaattg gatcttccaa gtggtgtaaa cgtagaaatc aaactttaat ctaaaatata
    30421 aaagagcaga ggctggtgtt tcaatctaat tgaacacggg ctaaactcgg tgtgaaaaag
    30481 ataaacttcc tcgcgtctgc tagacactgt gtcagtttcc tattttcact ttgagtttga
    30541 cgccctttgt atcttagact tgagcataaa aaacgctcgt taaaaacttt ttgaataaaa
    30601 aatatagaaa aggaactatt ttctcatgac aaaaggaatc ttagggaaaa aagtgggaat
    30661 gactcaaatc ttcactgaag ctggcgaatt gatccctgta acagttattg aagcaactcc
    30721 aaacgttgtt cttcaagtta aaactgttga aacagacgga tacaacgcta tccaagttgg
    30781 tttcgatgac aaacgcgaag tattgagcaa caaacctgct aaaggacatg tagcgaaagc
    30841 taacacggct cctaagcgct tcattcgtga attcaaaaac gttgaaggct tggaagttgg
    30901 tgctgaaatt acagttgaaa cattcgcagc tggagacgtt gttgacgtaa ctggtacttc
    30961 taaaggtaaa ggtttccaag gtgttatcaa acgccacgga caatcacgtg gaccaatggc
    31021 tcacggttct cgttaccacc gtcgtccagg ttctatggga cctgttgcac ctaaccgcgt
    31081 attcaaaggt aaaaaccttg caggacgtat gggtggtgac cgcgtaacaa ttcaaaatct
    31141 tgaagttgta caagttgttc cagaaaagaa cgttatcctt atcaaaggta acgtaccagg
    31201 tgctaagaaa tctcttatca ctatcaaatc agcagttaaa gctggtaaat aataaagaaa
    31261 ggggaaatca gtcacaatgg caaacgtaac attatttgac caaactggta aagaagctgg
    31321 ccaagttgtt cttagcgatg cagtatttgg tatcgaacca aatgaatcag ttgtgtttga
    31381 tgtaatcatc agccaacgcg caagccttcg tcaaggaaca cacgctgtta aaaaccgctc
    31441 tgcagtatca ggtggtggac gcaaaccatg gcgtcaaaaa ggaactggac gtgctcgtca
    31501 aggttctatc cgctcaccac aatggcgtgg tggtggtgtt gtcttcggac caactccacg
    31561 ttcatacggc tacaaacttc cacaaaaagt tcgtcgccta gctcttaaat cagtttactc
    31621 tgaaaaagtt gctgaaaaca aattcgtagc tgtagacgct ctttcattta cagctccaaa
    31681 aactgctgaa tttgcaaaag ttcttgcagc attgagcatc gattctaaag ttcttgttat
    31741 ccttgaagaa ggaaatgaat tcgcagctct ttcagctcgt aaccttccaa acgtgaaagt
    31801 tgcaactgct acaactgcaa gtgttcttga catcgcaaat agcgacaaac ttcttgtcac
    31861 acaagcagct atctctaaaa tcgaggaggt tcttgcataa tgaatttgta tgatgttatc
    31921 aaaaaacctg tcatcactga aagctcaatg gctcaacttg aagcagggaa atatgtattt
    31981 gaagttgaca ctcgtgcaca caaacttttg atcaagcaag ctgttgaagc tgctttcgaa
    32041 ggtgttaaag ttgccaatgt taacacaatc aacgtaaaac caaaagctaa acgtgttgga
    32101 cgttacactg gttttactaa caaaactaaa aaagctatca tcacacttac agctgattct
    32161 aaagcaatcg agttgtttgc tgctgaagct gaataatcta aggaggaaat atcgtgggaa
    32221 ttcgtgttta taaaccaaca acaaacggtc gccgtaatat gacttctttg gatttcgctg
    32281 aaatcacaac aagcactcct gaaaaatcat tgcttgttgc attgaagagc aaggctggtc
    32341 gtaacaacaa cggtcgtatc acagttcgtc accaaggtgg tggacacaaa cgtttctacc
    32401 gtttggttga cttcaaacgt aataaagaca acgttgaagc agttgttaaa acaatcgagt
    32461 acgatccaaa ccgttctgca aacatcgctc ttgtacacta cactgacggt gtgaaagcat
    32521 acatcatcgc tccaaaaggt cttgaagtag gtcaacgtat cgtttcaggt ccagaagcag
    32581 atatcaaagt cggaaacgct cttccacttg ctaacatccc agttggtact ttgattcaca
    32641 acatcgagtt gaaaccaggt cgtggtggtg aattggtacg tgctgctggt gcatctgctc
    32701 aagtattggg ttctgaaggt aaatacgttc ttgttcgtct tcaatcaggt gaagttcgta
    32761 tgattcttgg aacttgccgt gctacagttg gtgttgtcgg aaacgaacaa catggacttg
    32821 taaaccttgg taaagcagga cgtagccgtt ggaaaggtat ccgcccaaca gttcgtggtt
    32881 ctgtaatgaa ccctaacgat cacccacacg gtggtggtga aggtaaggca ccagttggtc
    32941 gtaaagcacc atctactcca tggggcaaac ctgctcttgg tcttaaaact cgtaacaaga
    33001 aagcgaaatc tgacaaactt atcgttcgtc gtcgcaacga gaaataatat taaactagtc
    33061 gcttaagcaa ctagtaaatc cgccagctcg gtagcgctcc ataggagtgc aagccgctgt
    33121 ggtacaacat ttaaaggaga aaatataaaa atgggacgca gtcttaaaaa aggacctttc
    33181 gtcgatgagc atttgatgaa aaaagttgaa gctcaagcta acgacgaaaa gaaaaaagtt
    33241 attaaaactt ggtcacgtcg atcaacgatc ttcccaagtt tcattggtta cactattgca
    33301 gtttatgacg gacgtaaaca cgtacctgtt tacatccaag aagacatggt aggccacaaa
    33361 cttggtgaat ttgcaccaac tcgtacttac aaaggtcacg ctgcagacga caagaaaaca
    33421 cgtagaaaat aaggagaaca taaatggcag aaattacttc agctaaagca atggctcgta
    33481 cagtacgtgt ttcacctcgt aaatcacgtc ttgttcttga taacatccgt ggtaaaagcg
    33541 tagccgatgc aatcgcaatc ttgacattca ctccaaacaa agctgctgaa atcatcttga
    33601 aagttttgaa ctcagctgta gctaacgctg aaaacaactt tggtttggat aaagctaact
    33661 tggtagtatc tgaagcattc gcaaacgaag gaccaactat gaaacgtttc cgtccacgtg
    33721 cgaaaggttc agcttcacca atcaacaaac gtacagctca catcactgta gctgttgcag
    33781 aaaaataagg aggtaaaatc gtgggtcaaa aagtacatcc aattggtatg cgtgtcggca
    33841 tcatccgtga ttgggatgcc aaatggtatg ctgaaaaaga atacgcggat taccttcatg
    33901 aagatcttgc aatccgtaaa ttcgttcaaa aagaacttgc tgacgcagca gtttcaacta
    33961 ttgaaatcga acgcgcagta aacaaagtta acgtttcact tcacactgct aaaccaggta
    34021 tggttatcgg taaaggtggt gctaacgttg atgcactccg tgcaaaactt aacaaattga
    34081 ctggaaaaca agtacacatc aacatcatcg aaatcaaaca acctgatttg gatgctcacc
    34141 ttgtaggtga aggaattgct cgtcaattgg agcaacgtgt tgctttccgt cgtgcacaaa
    34201 aacaagcaat ccaacgtgca atgcgtgctg gagctaaagg aatcaaaact caagtatcag
    34261 gtcgtttgaa cggtgcagat atcgcccgtg ctgaaggata ctctgaagga actgttccgc
    34321 ttcacacact tcgtgcagat atcgattacg cttgggaaga agcagatact acatatggta
    34381 aacttggtgt taaagtatgg atctaccgtg gtgaagttct tccagctcgt aaaaacacta
    34441 aaggaggtaa ataaccaatg ttagtaccta aacgtgttaa acaccgtcgt gaattccgtg
    34501 gaaaaatgcg cggtgaagca aaaggtggaa aagaagtagc attcggtgaa tacggtcttc
    34561 aagctacaac tagccactgg atcactaacc gccaaatcga agctgctcgt atcgccatga
    34621 ctcgttacat gaaacgtggt ggtaaagttt ggattaaaat cttcccacac aaatcataca
    34681 ctgctaaagc tatcggtgtg cgtatgggat ctggtaaagg ggcacctgaa ggttgggtag
    34741 caccagttaa acgtggtaaa gtgatgttcg aaatcgctgg tgtatctgaa gagattgcac
    34801 gtgaagcgct tcgacttgct agccacaaat tgccagttaa atgtaaattc gtaaaacgtg
    34861 aagcagaata aggagaaggc atgaaactta atgaagtaaa agaatttgtt aaagaacttc
    34921 gtggtctttc tcaagaagaa ctcgcgaagc gcgaaaacga attgaaaaaa gaattgtttg
    34981 aacttcgttt ccaagctgct actggtcaat tggaacaaac agctcgcttg aaagaagtta
    35041 aaaaacaaat cgctcgtatc aaaacagttc aatctgaagc gaaataatag actagggaag
    35101 gagaaatttc aatggaacgc aataatcgta aagttcttgt tggacgtgtt gtatctgaca
    35161 aaatggacaa gacaatcaca gttgtagttg aaacaaaacg taaccaccca gtctatggta
    35221 aacgtattaa ctactctaaa aaatacaaag ctcatgatga aaacaatgtt gccaaagaag
    35281 gcgatatcgt acgtatcatg gaaactcgcc cgctttcagc tacaaaacgt ttccgtcttg
    35341 tagaagttgt tgaagaagcg gtcatcatct aatcaaacct gaaaggagaa aactgaaatg
    35401 attcaaacag aaactcgttt gaaagtcgca gacaacagcg gtgctcgcga aatcttgact
    35461 atcaaagttc ttggtggttc aggacgtaaa tttgcaaaca tcggtgatgt tatcgtggca
    35521 tctgtaaaac aagctactcc tggtggtgcg gttaaaaaag gtgacgttgt taaagcagtt
    35581 atcgttcgta ctaaatcagg tgctcgtcgt gctgatggtt catacatcaa atttgacgaa
    35641 aacgcagcag ttatcatccg tgaagacaaa actcctcgcg gaacacgtat ctttggccca
    35701 gttgcacgtg aattgcgtga aggtggcttc atgaagatcg tgtcacttgc tccagaagta
    35761 ctttaatttt taggaacaaa ctagtcccct agcttcaagc tagggtgccc ttatgggcgt
    35821 aagaaaaatc aaggagaaac ctaatgtttg taaaaaaagg cgacaaagtt cgcgtaatcg
    35881 ctggtaaaga taagggaaca gaagctgttg tccttactgc ccttccaaaa gtaaacaaag
    35941 ttatcgttga aggtgttaac attgttaaga aacaccaacg tccaactaac gagcttcctc
    36001 aaggtggtat catcgagaaa gaagcagcta tccacgtatc aaatgttcaa gttttggata
    36061 aaaatggtgt agctggtcgt gttggttaca aatttgtaga cggtaaaaaa gttcgctaca
    36121 acaaaaaatc aggcgaagtg cttgattaat cacgaaggaa aggagaagta taatggcaaa
    36181 tcgtttaaaa gaaaaatatc ttaatgaagt agttcctgct ttgacagaac aattcaacta
    36241 ctcatcagtg atggctgtgc ctaaagtaga taagattgtt ttgaacatgg gtgttggtga
    36301 agctgtatca aacgctaaaa gccttgaaaa agctgctgaa gaattggcac ttatctcagg
    36361 tcaaaaacca cttatcacta aagctaaaaa atcaatcgcc ggcttccgtc ttcgtgaagg
    36421 tgttgcgatc ggtgcaaaag ttacccttcg tggtgaacgt atgtacgaat tcttggataa
    36481 attggtatca gtttcacttc cacgtgtacg tgacttccac ggtgtcccaa caaaatcatt
    36541 tgatggacgc gggaactaca cacttggtgt gaaagaacaa ttaatcttcc cagaaatcaa
    36601 cttcgatgac gttgacaaaa ctcgtggtct tgacatcgtt atcgtaacaa ctgctaacac
    36661 tgacgaagag tcacgtgcat tgcttacagg ccttggaatg ccttttgcaa aataatatag
    36721 gaggtaaatc taatggctaa aaaatcaatg gtagctagag aggctaaacg ccaaaaaatt
    36781 gttgaccgtt atgctgaaaa acgtgctgca ttaaaggcgg caggggacta cgaaggttta
    36841 tctaaattac ctcgcaacgc ctcaccgact cgtttacata atcgttgtag ggttacgggg
    36901 cgcccacatt cagtttaccg caaatttggt ctgagtcgta tcgcttttcg cgaacttgcg
    36961 cataaaggtc aaattcctgg tgtaacaaaa gcatcttggt aatttaagat atcaagagtg
    37021 tcaaaactcc aagtaaaaat aggaaacttg acgaagaaac taaagtttct aggaaagttt
    37081 atctttttca cacagagttt agcccgggtt caattgggct tgccaatttg aacacgagct
    37141 acagctttgg caaaaaagac caatttgctt tggagcattg cttctgcatt aaattgtcta
    37201 tttttgctcg tgctgttacg ctctttgtat catgtattaa ctagcaagtg caacttgcaa
    37261 actactagta agaggagaaa aacaaaatgg ttatgactga cccaatcgca gacttcctaa
    37321 ctcgtattcg taatgctaac caagctaaac acgaagtact tgaagtacct gcatcaaaca
    37381 tcaaaaaagg gattgctgaa atccttaaac gcgaaggttt tgtaaaaaac gttgaaatca
    37441 ttgaagatga caaacaaggc gtcatccgtg tatttcttaa atacggacca aatggtgaga
    37501 aagttatcac taacttgaaa cgtgtttcta aaccaggact tcgtgtctac aaaaaacgtg
    37561 aagaccttcc aaaagttctt aacggacttg gaattgccat cctttcaact tctgaaggtt
    37621 tgcttactga taaagaagca cgccaaaaga atgttggtgg tgaggttatc gcttacgttt
    37681 ggtaaaatca agatacaaag ctcgtaaaga acaaagcaaa attaggaagt tggagaagtt
    37741 tgtttacaaa caagccaact tatctatttt gcacagttct tagagcgtgt tcagttcagc
    37801 tcttgaacta aataagtatc tgaaccccgt gaaaactggc cgttctggcc tgacaattta
    37861 acaggagaaa ataaacatgt cacgtattgg taataaagtt atcgtgttgc ctgctggtgt
    37921 tgaactcgct aacaatgaca acgttgtaac tgtaaaagga cctaaaggag aacttactcg
    37981 tgagttctca aaagatattg aaatccgtgt ggaaggtact gaaataactc ttcaccgtcc
    38041 aaacgattca aaagaaatga aaactatcca cggaactact cgtgcccttt tgaacaacat
    38101 ggttgttggt gtatcagaag gattcaagaa agaacttgaa atgcgtgggg ttggttaccg
    38161 tgcacagctt caaggatcta aacttgtttt ggctgttggt aaatctcatc cagacgaagt
    38221 tgaagctcca gaaggaatta cttttgaact tccaaaccca acaacaatcg ttgttagcgg
    38281 aatttcaaaa gaagtagttg gtcaaacagc tgcttacgta cgtagccttc gttcaccaga
    38341 accatataaa ggtaaaggta tccgttacgt tggtgaattc gttcgccgta aagaaggtaa
    38401 aacaggtaaa taatgttgag tggttgatca tcaaccacca acctattttc caactttgtg
    38461 catagcacac gatttaaaac taaagaggtg aaaactgtga tttcaaaacc agataaaaac
    38521 aaactccgcc aaaaacgcca ccgtcgcgtt cgcggaaaac tctctggaac tgctgatcgc
    38581 ccacgtttga acgtattccg ttctaataca ggcatctacg ctcaagtgat tgatgacgta
    38641 gcgggtgtaa cgctcgcaag tgcttcaact cttgataaag aagtttcaaa aggaactaaa
    38701 actgaacaag ccgttgctgt cggtaaactc gttgcagaac gtgcaaacgc taaaggtatt
    38761 tcagaagtgg tgttcgaccg cggtggatat ctatatcacg gacgtgtgaa agctttggct
    38821 gatgcagctc gtgaaaacgg attgaaattc taataggagg acactagaaa atggcattta
    38881 aagacaatgc agttgaatta gaagaacgcg tagttgctgt caaccgtgtt acaaaagttg
    38941 ttaaaggtgg acgtcgtctt cgtttcgcag ctcttgttgt tgttggtgac cacaatggtc
    39001 gcgtaggatt tggtactggt aaagctcaag aagttccaga agcaatccgt aaagcagtag
    39061 atgatgctaa gaaaaacttg atcgaagttc ctatggttgg aacaacaatc ccacacgaag
    39121 ttctttcaga attcggtgga gctaaagtat tgttgaaacc tgctgtagaa ggttctggag
    39181 ttgccgctgg tggtgcagtt cgtgccgttg tggaattggc aggtgtggca gatattacat
    39241 ctaaatcact tggttctaac actccaatca acattgttcg tgcaactgtt gaaggtttga
    39301 aacaattgaa acgcgctgaa gaaattgctg cccttcgtgg tatttcagtt tctgatttgg
    39361 cataagaaag gggataaaat ggctcaaatt aaaattactt tgactaagtc tccaatcgga
    39421 cgcattccat cacaacgtaa aactgttgta gcacttggac ttggcaaatt gaacagctct
    39481 gttattaaag aagataacgc tgctatccgt ggtatgatca cagcagtatc tcacttagta
    39541 acagttgaag aagtaaacta atgaagtttt aggggatgtg cactgtacca tcccctaaaa
    39601 ctagatatag tcatctatga tgacatcgta taggcgagtt gatgggggag acaacctttt
    39661 ctcccttatc ggcgctagca ttttacaaaa gaggagaaaa taaaaatgaa acttcatgaa
    39721 ttgaaacctg cagaaggttc tcgtaaagta cgtaaccgcg ttggtcgtgg tacttcatca
    39781 ggtaacggta aaacatctgg tcgtggtcaa aaaggtcaaa aagctcgtag cggtggcgga
    39841 gttcgccttg gttttgaagg tggacaaact ccattgttcc gtcgtcttcc aaaacgtgga
    39901 ttcactaaca tcaacgctaa agaatacgca attgtgaacc ttgaccaatt gaacgtcttt
    39961 gaagatggtg ctgaagtaac tccagttgtt cttatcgaag caggaattgt taaagctgaa
    40021 aagtcaggta ttaaaattct tggtaacggt gagttgacta agaaattgac tgtgaaagca
    40081 gctaaattct ctaaatcagc tgaagaagct atcactgcta aaggtggttc agtagaagtc
    40141 atctaagaga ggtgacctat gttttttaaa ttattaagag aagctcttaa agtcaagcag
    40201 gttcgatcaa aaattttatt tacaattttt atcgttttgg tctttcgtat cggaactagc
    40261 attacagttc ctggtgtgaa tgccaatagc ttgaatgctt taagtggatt atccttctta
    40321 aacatgttga gcttggtgtc ggggaatgcc ctaaaaaact tttcgatttt tgccctagga
    40381 gttagtccct atatcactgc ttctattgtt gtccaactct tgcaaatgga tattttaccc
    40441 aagtttgtag agtggggtaa acaaggggaa gtaggtcgaa gaaaattgaa tcaagctact
    40501 cgttatattg ctctagttct cgcttttgtg caatctatcg ggattacagc tggttttaat
    40561 accttggctg gagctcaatt gattaaaact gctttaactc cacaagtttt tctgacgatt
    40621 ggtatcatct taacagctgg tagtatgatt gtcacttggt tgggtgagca aattacagat
    40681 aagggatacg gaaacggtgt ttccatgatt atctttgccg ggattgtttc ctcaattcca
    40741 gagatgattc agggcatcta tgtggactac tttgtgaacg tcccaagtag ccgtatcact
    40801 tcatctatca ttttcgtaat cattttgatt attactgtat tgttgattat ttactttaca
    40861 acttatgttc aacaagcaga atacaaaatt ccaatccaat atactaaggt tgcacaaggt
    40921 gctccatcta gctcttacct tccgttaaag gtaaatcctg ctggagttat ccctgttatc
    40981 tttgccagtt cgattactgc agcgcctgcg gctattcttc agtttttgag tgccacaggt
    41041 catgattggg cttgggtaag ggtagcacaa gagatgttgg caactacttc tccaactggt
    41101 attgccatgt atgctttgtt gattattctc tttacattct tctatacgtt tgtacagatt
    41161 aatcctgaaa aagcagcaga gagcctacaa aagagtggtg cctatatcca tggagttcgt
    41221 cctggtaaag gtacagaaga atatatgtct aaacttcttc gtcgtcttgc aactgttggt
    41281 tccctcttcc ttggtgtgat ttccatttta ccgattgcag ctaaagatgt atttggtctt
    41341 tctgatgttg ttgcctttgg tggaacaagt ctcttgatca ttatctctac aggtatcgaa
    41401 ggaatcaagc aattggaagg ttacctattg aaacgtaagt atgttggttt catggacaga
    41461 acagaataaa agtatttact gaatcagtaa atgctgaggg agtggaggtt taaactctga
    41521 catttgtaag agttggatct cccctcttct attttgtttt taaatagggg tgaaaagact
    41581 ttttgcttct atttaaaaat aaaataagga gatcaaatca tgaatctttt gattatgggc
    41641 ttacctggtg caggtaaggg aactcaagca gcaaaaatcg tagaacaatt ccatgttgca
    41701 catatctcaa caggtgatat gttccgcgct gcaatggcaa atcaaactga aatgggtgtt
    41761 cttgctaagt catatattga caagggtgaa ttggttcctg acgaagttac aaatggaatc
    41821 gtaaaagaac gcctttcaca agatgatatt aaagaaacag gattcttatt ggatggttac
    41881 ccacgtacaa ttgaacaagc tcatgccttg gacaaaacat tggctgaact tggcattgaa
    41941 ctagaaggtg ttatcaatat tgaagtgaac cctgacagcc tcttggaacg tttgagtggc
    42001 cgtatcatcc accgcgtaac tggagaaact ttccacaagg tctttaaccc accagttgac
    42061 tataaagaag aagattacta ccaacgtgaa gatgataagc ctgagacagt aaaacgtcgt
    42121 ttggatgtta atattgctca aggagaacca atcattgctc actaccgtgc caaaggtttg
    42181 gttcatgaca tcgaaggtaa tcaagatatc aatgatgtct tctcagatat tgaaaaagta
    42241 ttgacaaatt tgaaataaag cgtttttcat acttgcaaaa attcgctaca aatgttatac
    42301 tgagatagtc tgacttataa ttgttgtctc tgtgtctaga ggcatcgaat cgaaatttat
    42361 ggaggtgctt ttgcgtggca aaagacgatg tgattgaagt tgaaggcaaa gtagttgata
    42421 caatgccgaa tgcaatgttt acggttgaac ttgaaaatgg acatcagatt ttagcaacag
    42481 tttctggtaa aattcgtaaa aactatattc gtattttagc gggagatcgt gttactgtcg
    42541 aaatgagtcc atatgacttg acacgtggac gtatcactta ccgctttaaa taatcgaaaa
    42601 acttggaggg ataagaaatg aaagtaagac catcggtcaa accaatttgc gaatactgta
    42661 aagttattcg tcgtaatggt cgtgttatgg taatttgccc agcaaatcca aaacacaaac
    42721 aacgtcaagg ataagataga aaggagaaaa catggctcgt attgctggag ttgatattcc
    42781 aaatgacaaa cgcgtagtaa tctcattgac ttatgtttat ggtatcggac ttgcaacatc
    42841 taagaaaatt ttggctgctg ctggaatctc agaagatgtt cgtgtacgtg atcttacatc
    42901 agatcaagaa gatgctatcc gtcgtgaagt ggatgcaatc aaagttgaag gtgaccttcg
    42961 tcgtgaagta aacttgaaca tcaaacgttt gatggaaatc ggttcatacc gtggtatccg
    43021 tcaccgtcgt ggacttcctg tccgtggaca aaacactaaa aacaacgctc gcactcgtaa
    43081 aggtaaagct gttgcgattg ctggtaagaa aaaataatat aggaggtaaa agtcttggct
    43141 aaaccaacac gtaaacgtcg tgtgaaaaag aatatcgaat ctggtattgc tcatattcac
    43201 gctacattta ataacactat tgttatgatt actgatgtgc atggtaatgc aattgcttgg
    43261 tcatcagctg gtgctcttgg tttcaaaggt tctcgtaaat ctacaccatt cgctgctcaa
    43321 atggcttctg aagctgctgc taaatctgca caagaacacg gtcttaaatc agttgaagtt
    43381 actgtaaaag gtccaggttc tggtcgtgag tcagctattc gtgcgcttgc tgccgctggt
    43441 cttgaagtaa cagcaattcg tgatgtgact ccagtgccac acaatggtgc tcgtcctcca
    43501 aaacgtcgcc gtgtataatc atcgcattac actgcttttc gtttaagagg gagtaactaa
    43561 atgatcgagt ttgaaaaacc aaatataaca aaaattgatg aaaataaaga ttatggcaag
    43621 tttgtaatcg aaccacttga acgtggctac ggtacaactc ttggtaactc tcttcgtcgt
    43681 gtacttctag cttctctacc aggagcagct gtgacatcta tcaacattga tggtgtgtta
    43741 catgagtttg acacagttcc aggtgttcgt gaagacgtga tgcaaatcat tctgaacatt
    43801 aaaggaattg cagtgaaatc gtacgttgaa gacgaaaaaa tcatcgaact ggatgttgaa
    43861 ggtcctgctg aagtaacagc tggtgacatt ttgacagata gcgatattga aattgtaaat
    43921 ccagatcatt atctctttac aatcggtgaa ggttcttctc taaaagcgac tatgactgtt
    43981 aacagtggtc gtggatatgt acctgctgat gaaaataaaa aggataatgc accagttgga
    44041 acacttgctg tagattctat ttatacacca gttacaaaag tcaactatca agtggaacct
    44101 gctcgtgtag gtagcaatga tggtttcgac aaattaaccc ttgaaatctt gacaaatgga
    44161 acaattattc cagaagatgc tttagggctt tcagcacgta ttttgacaga acatcttgat
    44221 ttgtttacaa atcttactga gattgctaag tcaactgaag tgatgaaaga agctgatact
    44281 gaatctgacg accgtatttt agatcgtacg attgaggaac tggacttgtc tgtgcgttca
    44341 tacaactgtt taaaacgtgc cggtatcaat actgtgcatg atttgacaga aaaatctgaa
    44401 gcagagatga tgaaagtacg aaatcttgga cgcaagagtt tggaagaagt gaaactcaaa
    44461 ctcattgatt tgggtcttgg attaaaagat aaataaagga ggaatacatg gcttaccgta
    44521 aactaggacg cactagctca caacgtaaag caatgcttcg cgatttgaca actgaccttt
    44581 tgatcaacga atcaatcgtg acaactgaag ctcgtgctaa agaaatccgt aaaactgttg
    44641 aaaaaatgat tactctaggt aaacgtggtg atttgcatgc acgtcgtcaa gcagctgctt
    44701 tcgtacgtaa tgaaatcgca tctgaaaact atgatgaagc aactgataag tacacttcta
    44761 ctacagcact tcaaaaattg ttctcagaaa tcgcacctcg ttatgctgaa cgtaacggtg
    44821 gatacactcg tatccttaaa actgaaccac gtcgtggtga tgcagcgcca atggcgatca
    44881 tcgaattagt ataaaatcat caattttgtt gagtgttatg atgatggagt cttgtgctct
    44941 tagtctagct ctggtctacc gctaggattt cggtcctagc gggaacactc atcataagtt
    45001 gggatagtag acgcttgttt acgaaattgt ttttttctta agaacaactt cgtaagcagg
    45061 cgtttttgag tattttcgtt agaattatgc tatactattt gaaaagaatc ctgtttaatg
    45121 ttaaggtttc ttattttaag aagaattgga gtttacttat gaaagccatt ataactgttg
    45181 ttggtaaaga taaatctgga attgttgcag gtgtttctgg taaaattgca gaattaggat
    45241 tgaatattga cgatatctct caaactgtat tggatgaata ttttacgatg atggctgttg
    45301 tatctagtga tgaaaagcaa gattttacct atcttcgtaa tgaatttgaa gcttttgggc
    45361 aaactttgaa tgtaaaaatc aatattcaga gtgcagcgat tttcgaagct atgtataata
    45421 tctaggaggt catcatggat attagacaag ttactgaaac catcgccatg attgaggagc
    45481 aaaacttcga tattagaacc attaccatgg ggatttctct tttggactgt atcgatccaa
    45541 atatcaatcg tgctgcggag aaaatctatc aaaaaattac gacaaaggcg gctaatttag
    45601 tagctgttgg tgatgaaatt gcggctgagt tgggaattcc tatcgttaat aagcgtgtat
    45661 cggtgacacc tatttctctg attggggcag cgacagatgc gacggactac gtggttctgg
    45721 caaaagcgct tgataaggct gcgaaagaga ttggtgtgga ctttattggt ggtttttctg
    45781 ccttagtaca aaaaggttat caaaagggag atgagattct catcaattcc attcctcgcg
    45841 ctttggctga gacggataag gtctgctcgt cagtcaatat cggctcaacc aagtctggta
    45901 ttaatatgac ggctgtggca gatatgggac gaattatcaa ggaaacagca aatctttcag
    45961 atatgggagt ggccaagttg gttgtattcg ctaatgctgt tgaggacaat ccatttatgg
    46021 cgggtgcctt tcatggtgtt ggggaagcag atgttatcat caatgtcgga gtttctggtc
    46081 ctggtgtggt gaaacgtgct ttggaaaaag ttcgtggaca gagctttgat gtagtagccg
    46141 aaacagttaa gaaaactgcc tttaaaatca ctcgtatcgg tcaattggtt ggtcaaatgg
    46201 ccagtgagag actgggtgtg gagtttggta ttgtggactt gagtttggca ccaacccctg
    46261 cggttggaga ctctgtggca cgtgtccttg aggaaatggg gctagaaaca gttggcacgc
    46321 atggaacgac agctgccttg gccctcttga acgaccaagt taaaaagggt ggagtgatgg
    46381 cctgtaacca ggtcggtggt ctatctggtg cctttatccc tgtttctgag gatgaaggaa
    46441 tgattgctgc agtgcaaaat ggctctctta atttagaaaa actagaagct atgacggcta
    46501 tctgttctgt tggattggat atgattgcca tcccagaaga tacgcctgct gaaactattg
    46561 cggctatgat tgcggatgaa gcagcaatcg gtgttatcaa catgaaaaca acagctgttc
    46621 gtatcattcc caaaggaaga gaaggcgata tgattgagtt tggtggtcta ttaggaactg
    46681 cacctgttat gaaggttaat ggggcttcgt ctgtcgactt catctctcgc ggtggacaaa
    46741 tcccagcacc aattcatagt tttaaaaatt aagaaaatag gagaaatttt aagttctatt
    46801 taagattaga cgtgtatact ataatcatta aataaagacc tcctaatatt
//
LOCUS       DAVLBN010000008        46494 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLBN010000008 DAVLBN010000000
VERSION     DAVLBN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.008"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..749
                     /locus_tag="VXC24_000437"
                     /pseudo
     CDS             1..749
                     /locus_tag="VXC24_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(865..1668)
                     /locus_tag="VXC24_000438"
     CDS             complement(865..1668)
                     /locus_tag="VXC24_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0492607.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2048..3652)
                     /locus_tag="VXC24_000439"
     CDS             complement(2048..3652)
                     /locus_tag="VXC24_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0492608.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            complement(3703..3867)
                     /locus_tag="VXC24_000440"
     CDS             complement(3703..3867)
                     /locus_tag="VXC24_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0492609.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(3948..6599)
                     /locus_tag="VXC24_000441"
     CDS             complement(3948..6599)
                     /locus_tag="VXC24_000441"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0492610.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6592..7170)
                     /locus_tag="VXC24_000442"
     CDS             complement(6592..7170)
                     /locus_tag="VXC24_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0492611.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7170..7730)
                     /locus_tag="VXC24_000443"
     CDS             complement(7170..7730)
                     /locus_tag="VXC24_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492612.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(7717..8165)
                     /locus_tag="VXC24_000444"
                     /pseudo
     CDS             complement(7717..8165)
                     /locus_tag="VXC24_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(8577..8972)
                     /locus_tag="VXC24_000445"
     CDS             complement(8577..8972)
                     /locus_tag="VXC24_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0492613.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(9068..9322)
                     /locus_tag="VXC24_000446"
     CDS             complement(9068..9322)
                     /locus_tag="VXC24_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0492614.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9332..10666)
                     /locus_tag="VXC24_000447"
     CDS             complement(9332..10666)
                     /locus_tag="VXC24_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0492615.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(10666..10899)
                     /locus_tag="VXC24_000448"
     CDS             complement(10666..10899)
                     /locus_tag="VXC24_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0492616.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            10930..11007
                     /locus_tag="VXC24_000449"
                     /pseudo
     CDS             10930..11007
                     /locus_tag="VXC24_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11348..11530)
                     /locus_tag="VXC24_000450"
     CDS             complement(11348..11530)
                     /locus_tag="VXC24_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492617.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11532..12311)
                     /locus_tag="VXC24_000451"
     CDS             complement(11532..12311)
                     /locus_tag="VXC24_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492618.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(12591..12941)
                     /gene="rbfA"
                     /locus_tag="VXC24_000452"
     CDS             complement(12591..12941)
                     /gene="rbfA"
                     /locus_tag="VXC24_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0492619.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(13192..15984)
                     /gene="infB"
                     /locus_tag="VXC24_000453"
     CDS             complement(13192..15984)
                     /gene="infB"
                     /locus_tag="VXC24_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0492620.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(16001..16300)
                     /locus_tag="VXC24_000454"
     CDS             complement(16001..16300)
                     /locus_tag="VXC24_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0492621.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(16293..16586)
                     /locus_tag="VXC24_000455"
     CDS             complement(16293..16586)
                     /locus_tag="VXC24_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0492622.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(16608..17744)
                     /gene="nusA"
                     /locus_tag="VXC24_000456"
     CDS             complement(16608..17744)
                     /gene="nusA"
                     /locus_tag="VXC24_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0492623.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(17788..18267)
                     /gene="rimP"
                     /locus_tag="VXC24_000457"
     CDS             complement(17788..18267)
                     /gene="rimP"
                     /locus_tag="VXC24_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0492624.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(18393..19028)
                     /gene="trmB"
                     /locus_tag="VXC24_000458"
     CDS             complement(18393..19028)
                     /gene="trmB"
                     /locus_tag="VXC24_000458"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0492625.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQDPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(19025..19819)
                     /locus_tag="VXC24_000459"
     CDS             complement(19025..19819)
                     /locus_tag="VXC24_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0492626.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(19980..20591)
                     /locus_tag="VXC24_000460"
     CDS             complement(19980..20591)
                     /locus_tag="VXC24_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0492627.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(20742..20975)
                     /locus_tag="VXC24_000461"
     CDS             complement(20742..20975)
                     /locus_tag="VXC24_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492628.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(21017..21706)
                     /locus_tag="VXC24_000462"
     CDS             complement(21017..21706)
                     /locus_tag="VXC24_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0492629.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(21758..22141)
                     /locus_tag="VXC24_000463"
     CDS             complement(21758..22141)
                     /locus_tag="VXC24_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0492630.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(22770..23141)
                     /locus_tag="VXC24_000464"
     CDS             complement(22770..23141)
                     /locus_tag="VXC24_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492631.1"
                     /translation="MIKKNHILCEIVPGAVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            complement(23610..23729)
                     /locus_tag="VXC24_000465"
     CDS             complement(23610..23729)
                     /locus_tag="VXC24_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0492632.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(23833..23982)
                     /gene="blpO"
                     /locus_tag="VXC24_000466"
     CDS             complement(23833..23982)
                     /gene="blpO"
                     /locus_tag="VXC24_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0492633.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(24226..24429)
                     /gene="blpN"
                     /locus_tag="VXC24_000467"
     CDS             complement(24226..24429)
                     /gene="blpN"
                     /locus_tag="VXC24_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0492634.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(24445..24699)
                     /gene="blpM"
                     /locus_tag="VXC24_000468"
     CDS             complement(24445..24699)
                     /gene="blpM"
                     /locus_tag="VXC24_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0492635.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            24979..27104
                     /gene="blpA"
                     /locus_tag="VXC24_000469"
                     /pseudo
     CDS             24979..27104
                     /gene="blpA"
                     /locus_tag="VXC24_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            27115..28476
                     /locus_tag="VXC24_000470"
     CDS             27115..28476
                     /locus_tag="VXC24_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0492636.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            28533..28688
                     /gene="blpC"
                     /locus_tag="VXC24_000471"
     CDS             28533..28688
                     /gene="blpC"
                     /locus_tag="VXC24_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0492637.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(28732..30072)
                     /locus_tag="VXC24_000472"
     CDS             complement(28732..30072)
                     /locus_tag="VXC24_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0492638.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(30086..30823)
                     /locus_tag="VXC24_000473"
     CDS             complement(30086..30823)
                     /locus_tag="VXC24_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492639.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(30828..31166)
                     /locus_tag="VXC24_000474"
     CDS             complement(30828..31166)
                     /locus_tag="VXC24_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492640.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            31442..31771
                     /locus_tag="VXC24_000475"
     CDS             31442..31771
                     /locus_tag="VXC24_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0492641.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(31939..32988)
                     /locus_tag="VXC24_000476"
     CDS             complement(31939..32988)
                     /locus_tag="VXC24_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492642.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(32985..33716)
                     /locus_tag="VXC24_000477"
     CDS             complement(32985..33716)
                     /locus_tag="VXC24_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492643.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            33784..34194
                     /locus_tag="VXC24_000478"
     CDS             33784..34194
                     /locus_tag="VXC24_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0492644.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            34204..34491
                     /locus_tag="VXC24_000479"
     CDS             34204..34491
                     /locus_tag="VXC24_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492645.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            34653..34892
                     /locus_tag="VXC24_000480"
     CDS             34653..34892
                     /locus_tag="VXC24_000480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492646.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(35214..36350)
                     /gene="dnaJ"
                     /locus_tag="VXC24_000481"
     CDS             complement(35214..36350)
                     /gene="dnaJ"
                     /locus_tag="VXC24_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0492647.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(36555..36809)
                     /locus_tag="VXC24_000482"
     CDS             complement(36555..36809)
                     /locus_tag="VXC24_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492648.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(36922..38745)
                     /gene="dnaK"
                     /locus_tag="VXC24_000483"
     CDS             complement(36922..38745)
                     /gene="dnaK"
                     /locus_tag="VXC24_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0492649.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(39225..39749)
                     /gene="grpE"
                     /locus_tag="VXC24_000484"
     CDS             complement(39225..39749)
                     /gene="grpE"
                     /locus_tag="VXC24_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0492650.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(39776..40810)
                     /gene="hrcA"
                     /locus_tag="VXC24_000485"
     CDS             complement(39776..40810)
                     /gene="hrcA"
                     /locus_tag="VXC24_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0492651.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(40974..41411)
                     /locus_tag="VXC24_000486"
     CDS             complement(40974..41411)
                     /locus_tag="VXC24_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0492652.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            42091..44424
                     /locus_tag="VXC24_000487"
     CDS             42091..44424
                     /locus_tag="VXC24_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0492653.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            44437..45900
                     /locus_tag="VXC24_000488"
     CDS             44437..45900
                     /locus_tag="VXC24_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0492654.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            45900..>46494
                     /locus_tag="VXC24_000489"
     CDS             45900..>46494
                     /locus_tag="VXC24_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0492655.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDN"
BASE COUNT        14296 a         9821 c         8400 g        13977 t
ORIGIN      
        1 aaaacagata aggaccaaga gcttaaagct gaaattcaat ccatctttat cgaacacaag
       61 ggaaattatg gttatcgtcg gatttattta gaactaagaa atcgtggtta tctggtaaat
      121 cataaaagag ttcaacactt gatgaagtac tcaatttaca agctaaaatg cgacagaaac
      181 gaaaatattc ttctcataaa ggagacgttg gcaagaaggc agagaatctc attcaaggcc
      241 aatttgaagg ctctaaaaca atggaacagt gctacacaga tgtgacagaa tttgccattc
      301 cagcaagtac tcaaaagctt tacttatcac cagttttaga tggctttaat agcgaaatta
      361 tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg
      421 cattcacaga gaagcactat gagaatacga ttctccatag tgaccaaggc tggcaatacc
      481 gacacgattc ttatcatcgg ttcctagaga gtaagggagt tcaagcatcc atgtcacgca
      541 agggaaacag ccaagacaac ggtatgatgg aatctttctt tgggattctg aaatcggaaa
      601 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gctattgtag
      661 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagtcctg
      721 tgcaatacag aactaaatcc ttcggataaa ttaattgtct aactgtttgg ggtcagtaca
      781 cctaaaactt tgatgatata cgttttcttg tgagaatatt tacttcattt ttgcctaaaa
      841 ttcaatgttt actcagtatt tggattatga aaaatcaagg tctaaatcta gatacatttt
      901 ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa
      961 ctcaggacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac gaaaatattt
     1021 ggaatgttgc tgaaatggtg tattatcaat atcaaaacca aactcacgaa gatactgaat
     1081 caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc
     1141 tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg catatgcaac
     1201 ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt aatcagagta
     1261 cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct gacgaaattg
     1321 ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa tagcaagtaa
     1381 ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac gtagagaaac
     1441 caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg catcctcata
     1501 aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt ccatatacgc
     1561 tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata aatcacgctt
     1621 cgcttcataa gacaagtttg gattgtcaat gttgtaagtt ggttgcatag aaatatcctt
     1681 tcaattgttt ttctgtgtca tcggtaaatg gtgaaatggg tatggaattg gcgaaaatta
     1741 taaaaatcct tcacaataag ttctatgaaa tatatatact tcatcttaat agtgagcaag
     1801 ctaaacttag catttcatgc cctcatatgg gatgttcttt gactaaataa tatgattatc
     1861 gagatatatc tggataaatg aactaataag tctgacgcgc atacttatca aactcattgg
     1921 catacacctc tatgaactcg ttggtctgtt caaatcccaa cacattacct gagaagaaag
     1981 ttgcaatgtt gtttttggtg cgggtttgaa tttaaaaaat ttgttatgta gtacctaatc
     2041 taaggaatta gaacaatgcc tctaattttt ctttaataca ctgaaacatt gatgattctg
     2101 gctgtatttt tgaaacagct cttctttgct cctggaaaat atcttcagaa gttatattct
     2161 ctattcctaa cgctacttga gttttttttc taaaatattc ttttccgttg ccatctttag
     2221 aaaaatcata accttcccta tctacgctgt tacacaaatt agctaaaaaa aactctgggg
     2281 ttgggaaagg aagataagaa acgtatttag cccaataatc tataaagctt ctttgtttcg
     2341 caattaattc aatattattt ttttgccctt tattacctga aacattaaat ttaattggac
     2401 atcccgttat caattttata atatcatcaa gatttttatt atctgattca ggaattttat
     2461 ctgatataac aacaccattt tcaagatagt tcattaaatt atttgattca ctaacattag
     2521 tgttttgatc tccatcaaac caaaaataat ggttatcgga atctaaatac gatgagttta
     2581 aaatattatt acaaattatt tgatttgctc caccaggaat atatctcact actaaattct
     2641 gtttaagatt ctcactacct gaatgagtga taacaaactc tagaatatat ttagctagtc
     2701 tatcttcaac ataaatcatc ttcctagaat gatacacatc acctaattca aaaaatgcat
     2761 cctgataatc aatattttca ataacatcta ccttttctcc gtttttcact aaaagtttca
     2821 cggcttctct aagaaaatct tttataagtt gtgtagaatg tgtagtgata ataatttgat
     2881 gttttttatt taaacactct tgaagtaaaa actctttaaa tttatagatt gcactcggat
     2941 gaagtgagat ttcaggttca tctattaata ttaatgaatt tgattgcgca tttactatat
     3001 catttactaa caaaataatt ctagcctcac ctgttcctgc aaaagcctcg gaatattctt
     3061 ttccagattt tttcatccaa atagttttgg aagcttttat atcatcacct tttgaataca
     3121 acttatgtgt taaaatttga atgtctgtat aagattcatc cattatttca ctaataattt
     3181 cacaaacttt atcatcaact ttaacattat ctataaccat ttccttttta taacgcgtat
     3241 aactacttgt attattcttt aaaatatcag caactggttt agatcgtaat cttataaaat
     3301 cttgtttact acgttgagta gaaatttttt taaaattata gtgatagaaa aataaatcaa
     3361 aagcagaaac atattcttta caatcacaaa agacaacatt tttttcaatg ccatcccatc
     3421 tgtctgtcga agaacttcca atatatttat ttttgggtaa tctttccatc tcatattgtt
     3481 tttgaggagc atatggttcc caataatcta atcctttttt tgttccagaa cggcctttaa
     3541 gaacttctac atttctagaa gctttaacgt tataatatga atagattaaa cattgtttcc
     3601 catccacttc atctatttga tcaacatttg tactaaacca atattcagac acacttttat
     3661 tggctggaga accatataaa gcttgtaaaa ttgaagtttt atttactcca tatctattac
     3721 agacacctca ggattattta acttataagt tttaacagct acggaatcaa tttcaacagc
     3781 aacttgaaca tctatgcctg attttttaag gccacttgta gtgccacctg caccgttaaa
     3841 taaatcaata gcaacaattt tccccatagt attctcctaa agtttctcct ttttattata
     3901 acattatcaa atgtaaaacc caacccgata gggttaggtt tttaacatca tttcaccaac
     3961 ttcttcatct catcaatacg tgctacggtc gcatcatact tggcttggta gtcggcttgt
     4021 ttgtcttttt ctttttggac aacttctggt ttagcgttgg cgacgaagcg ttcgttgctg
     4081 agttttttgc caaccatgtc gagttctttc tgccatttgg caagttcttt ttccagacgt
     4141 gccaattctt cttcgacatt caagaggtct accagtggca agaagatttc ggctcctgta
     4201 ataacgcttg acatagccag ttcaggtgca gggatggttg atgcgatttc caagtgttct
     4261 ggatttgtaa agcgtttgat atagttgaca ttgctgttaa agaaggcttc caagtcgcta
     4321 tcgcttgtct taacaaggat ggtgataggt ttgcttggtg ctacatttac ttccgcacgc
     4381 gcattacgaa cggcacggat caagtctttg agactttcca caccagtgtg ggcagcaagg
     4441 tcctcaaagg ctgggttgac agttgggtat gctgctgtca cgatagagcc ttcagcgtac
     4501 tgaccaaaga tttcttctgt cacgaacggc attattgagt gaaggagacg aaggatttta
     4561 tccagcgtat agaggagaac agatcgagta attaccttat cgtcttcatt gtcgctgtaa
     4621 agaacttcct tggtcaactc aacataccag ttggcaaatt cttcccaaat gaagttgtaa
     4681 aggatatgac cagccacacc aaactcgaac ttatcaaagt tttcagtaac ttttgcaatg
     4741 gtttcgttga gattgtggag aatccagcgg tccgtcacat taccagcctc acctgttgca
     4801 acttttgtga cattgtcatg cgccacatcc agcgtcaaac ctccattgtt catgaggata
     4861 tagcgagaaa tgttccaaat cttgttaata aagttccatg aagcatccat tttctcataa
     4921 gagaaacgca cgtcttgtcc tggcgcagaa ccgtttgaaa ggaaccatcg aagggcatcg
     4981 gcaccgtatt tctcgataac atccattggg tcaatcccgt taccgagaga cttagacatc
     5041 ttgcgtcctt gctcgtcacg aatgagaccg tggataagga cgttttggaa tggttgacgg
     5101 cctgtgaatt ccaatgactg gaagatcata cgagacaccc agaagaagat gatgtcgtaa
     5161 cctgttacca aggttgaagt tgggaaataa cgtttaaagt cttctgagtc gacttcaggc
     5221 cagcccatgg ttgaaaatgg ccagagggca gaactgaacc aagtatccaa gacgtcttcg
     5281 tcctgagtcc atccgtcacc ttctggagct tcttcgccga catacatttc accatcagca
     5341 ttgtaccagg cagggatttg gtgaccccac caaagctgac gagagataac ccagtcgtgg
     5401 acattttcca tccattgaag gaaggtatcg ttgaaacgag gtgggtagaa ttcgaccttg
     5461 tcctctgtgt cttggttggc aatggcgttc ttagccaatt ggtccatctt gacgaaccat
     5521 tgagtagaca agcgtggctc aactacgaca cctgtacgtt ctgagtgacc aacactgtgg
     5581 acacgttttt cgattttgac aagggcaccg atttcttcca acttagcaat gactgcctta
     5641 cgagcttcaa aacgatccat gcctgaaaat tcaaaggcaa gctcattcat agttccgtcg
     5701 tcgttcatga cgttgacttg tggcaagtta tgacgttggc caaccaagaa gtcatttgga
     5761 tcgtgggcag gtgtgatttt cacgacacca gtaccaaact caggatctgc gtgctcatct
     5821 ccaacgattg ggatgagttt attagcgatt ggaaggatga cgtttttacc aatcaagtcc
     5881 ttgtagcgcg ggtcttctgg attaaccgca accgcaacgt ccccaaacat agtctcagga
     5941 cgagttgtag caacttcaag ggcgcgtgaa ccatcttcca gcatgtaatt catgtggtag
     6001 aaggcacctt ccacatcctt gtgaatcacc tcaatatcag aaagggctgt gcgagctgct
     6061 gggtcccagt tgatgataaa ctcaccacgg tagatccagc ctttcttgta aaggtccaca
     6121 aagaccttac gaacagcttt tgacaaacct tcgtcaagag tgaaacgctc acgagaatag
     6181 tctacagaga gccccatctt gccccattgt tccttgatgg tagtggcata ttcgtctttc
     6241 cattcccaga ctttcgtcaa gaaagactca cgaccaaggt catagcggga aatgccctca
     6301 ccacgcaagc gctcctcaac cttagcctga gtcgcaatac cagcgtggtc cattcctgga
     6361 agccaaagcg tatcaaaacc ttgcatgcgt ttttgacgga tgataatatc ttgcaaagtt
     6421 gtatcccaag cgtgaccaag gtgaagttta cctgtaacgt ttggtggtgg aataacgatt
     6481 gaataaggct tagccttttg atcgcctgaa ggcttgaaaa catcagcatc aagccatttt
     6541 tggtaacgac cagcctcaac ctcggctgga ttgtatttag atgaaagttc tttagacatg
     6601 tgtgtgtcct ttctctattt tgtttatttt attttgaatt tgcttagcag cttcttctgc
     6661 agacaaattc gtattattta ttttaaagta gtggtgcaac tcattcggtt gatattggga
     6721 atttaattga agtatttcag cggtctctat aatttctctt tcagatacct caatatgtcg
     6781 ttttaagggt ttgtacttta atcgattctc cgttcgattt cgacgtatgc actcttcaag
     6841 acttgtttcc aactcaacaa aaagaatctc ttgatgataa tcatccaaca aactctgaat
     6901 ttgctttaaa tatatcagat gatactgatt tgaaaaatca attacatctg ttaaaattac
     6961 tgatcgctga tttcttgcac tcgctccaag gaatgaaaaa gtgattccac gaacaaattc
     7021 ccacatttcc tctgtatagt cctgatagat ttctagtgca aaatcgatgg cttgatggtt
     7081 ataaaatagg gtagcatccg tcagtcgaga taattcttga ccaatggtca tttttcctga
     7141 tgctggagca ccaatgatga aaagatgcat caaatcacct cccattcact cttcagcaag
     7201 gcatatctta aatcatcaca gcagttgcct tgagcatctt tgcggtctct tatgcgagct
     7261 tcgagggtaa agtcaagctt ttccgcgact cgtttacttt gaaggttata tccaaagcaa
     7321 gttagttcaa tcttgtgaag acccaaatct ttaaaggcta agtcaatcaa ggcacgcgca
     7381 gcttctggca cataacctcg cccccaatag tctgggtgta aggtatagcc gatttccagc
     7441 acatcatctt catggcgatg gttgaaatcg acagagccaa cgatcttatc cgttcctttg
     7501 acgacaatcc cgtagcctgc tgggagattt tccttttgat tacgctccgg aaaaatgtgc
     7561 tccagataat aaatctcatc ttccaaggtc ttgactggag gaaaacctgc tggataggcg
     7621 acctctggca aactagcata gtcaaagata tcctcagcat ccgccacagt acggactcgt
     7681 aaaacgagac gttctgtttc gattttatct ggcagctcag ttcttgccat ccttcttcct
     7741 cgcttttttg atgaaactgc ccttcatatc tacacgcttg tccagatagc aataaacgcg
     7801 ctgatatcca tctcccatga aataggttgg gcaaacagtt gatttttaaa atgtcccttt
     7861 tcatccagga gttctggggc aacaagtcgc tcaagaatct tggcaaagat gtggcaaata
     7921 ccgtattcct caacaatcct atctacccga taatctaaaa caagtggaca ggcgtctaaa
     7981 ataggagtct gagttcgttc agaaatttca taatgcactc ccaaacgttc caatttctcc
     8041 tgatgactga taaaaccagc ctgctccatc gcaagcatag aagtttcatc agaaatattc
     8101 acagtaaatt tttgatattg tttgatctgc tctgcggcat tctctctcgc aacgactcca
     8161 atcacaaccc aatctcctag actataagag gaactacagg tcatgatgtt atagctaaaa
     8221 ttctgatctt gatatcctaa aataaaaaca ggaaaaccat aatatagttt attagtttta
     8281 aatgattgtt ttataacaac ctcctttgac taagacacaa aagaaaagcc ctgccatcta
     8341 catgacaggg acgaatgtgt ttatccgcgg taccacccaa tttcgggcca agcccgcatc
     8401 tttagtcttt aaaataaaaa gacagaaata tttcattttt tcagtcatta gcaaccagtt
     8461 ttgacacatt tgtggacttc tcagcgccgc cactttctgt aaaatgtggg attcaaaaca
     8521 cctctaatgg ctctattgta gcaagttttt ctcggaaatg caaggctcaa gaaaaattac
     8581 ttgaacttga tgccattttc tttcaatttc ttgatggtag ctgggccgat tcctttcaag
     8641 gcaaggagtt ctttttcagt ccagtttttg aaatctgaag cagacttgat tccttcatca
     8701 tagaaagtct tggcacgatc aagtggaagt ccccccaagt ttgctgcaaa atcttctaca
     8761 gaattagcta ctttttgagc ttgctctttg gtagcttcta ctgcttgttc aactttttta
     8821 gaaacagcct taccagctgc gcttgctggc tgttctgcac gcttcacgac tttttttgtc
     8881 tcatctacaa ccttagtcac agtacttgaa aaggcacctg cgcgacggag gccatttcgt
     8941 aattgttttt tacgattgag tttctttgac atgataaaat cctttcaata aaaaatccct
     9001 gctctgacaa ggatttaaca taaacattct atcaagattt tagtgaaaaa tcaagaatct
     9061 ttctcgttta ataatttcgc tcaccaaaca agccttctgg caaatcatgg aatcccttgc
     9121 ctgctttgaa gttttcaaac ttaccaagca agaactgata agcatccaag cgactctcgt
     9181 agcgaatcat ggcatctttg gcacgctcgt cctggtcttc ttcgtaaact ttttgacttt
     9241 ccttgtgcgc catgtcgtta atcatgattt gggtattgac ccaagcttca aattccttca
     9301 taaattcttg ttcgtaactc attttttctc cttattctaa tccacgaaaa tagtccgtat
     9361 caatctcacg gtagggctgg atatcctgaa catactccaa cactccttgg aattctccgt
     9421 cttcatcgtg tactgcagca taggtgatgt ggacaaactt acctcgcgac tcagacttga
     9481 accacatttc atacttgtct ttgcttccct cacgaagccc cttcatgata gttttgacct
     9541 tgtccaagta cttaggcgga tggcagagtt cgacattgcg cccgacttga gacggcgtcc
     9601 gtttgaaaat catctcatca gctggcgtat tgtcattgta atactggaaa atatcatctt
     9661 tattgacaaa ggtaatctcc atagggaggt gattgaggat gagattggcc tgctcgactg
     9721 aaagatagcc attaccaaaa gcctgttgac tatggcggtc cagcacagct tccttttcct
     9781 taggggtaaa ggtaatggta aaatggcctt ctggcgtatc tatgacttgt tgaacttgac
     9841 cttctgccgt atctagctgt acaggctcct ctgcaatctt ttcctcaata aagctctgtc
     9901 gttctggcac ccatttctct gacggacgga tgatggcata gccataggca tcgctctcct
     9961 ccgcaatctg aagccagtca tcctgagtaa aagactcaag gagaatcatg aggaggatgg
    10021 actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa agcttcaaaa gcttccttta
    10081 cactgctaat tgacacttct ggtagtgact tggctgtcgt tagagctgtt tgaaagagtt
    10141 ccctaatctg atcatccact ccccacataa ctttgggagg tgaatcgtgt ccatagcgct
    10201 ccatgatagg aaagaagagt tcttccttac gttggtaatg gatgtcaaat tgacccacaa
    10261 gtcccatctg acgcaccaaa cccttacgca tctccgccag catttcctcg tcttccatat
    10321 actcataggt atctaacaat ctacgaatgc gaatcaaggc cgcacggaga gccagatttt
    10381 cttctttgaa gacacgaact gggtgacctg gatgctcagt atctgaaact tcgacacctt
    10441 tgatagcatt tttaaaaaga ttggcatgga catcacagag ttccataaca tcttcaaagg
    10501 tgacacctga gtctgagttc atcagctcgt gctccataag ggaaatctcg atggctgaga
    10561 cacccgcaaa ggtcgcatca aagcgctctt gaaccgactc aggagaggcg ccattgtgca
    10621 attctaacaa aatatcccgt aggacatgaa tccgttcatc tgccattagt ctaatccaat
    10681 cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg tccataggag ttcctgctag
    10741 cttagaaccc tgtttgagcg ataccttgcg accaactgta ttgcgcatta agggattggc
    10801 aaggggttta aaacccaact ccactagaat ttccaagact tctggatgct tgtccaccac
    10861 ttctgcaaca ggaattgaca catcgatgat attgtccatg acgacctcca ttgtatgttc
    10921 taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcagactg ctcaaaacag
    10981 tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacaccgttt tgaggttgta
    11041 gatagaactg acgaagtcag taaccatacc tacagcaagg tgaagctgac gtggtttgaa
    11101 gagattttcg aagagtataa aatgatttta ctgcttatat tataccatat ggagagagat
    11161 taaaaaacta gcagtggggt tcctgctagt tttctgcgac ttggattacc atctagataa
    11221 gtttaaagaa ccaatccaat atcttgtaaa acagcaattg aactgcaaaa gaaatgatca
    11281 tccaaaagaa tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa
    11341 aaaaatttca ttctctctcc tctggcttaa tgagccaccg agccgtatcc attagcttat
    11401 ctgcaataaa aagtttgccc agaccaacaa cgacatggtc agctttcttt atcgttttca
    11461 tcacttttac accttgcacg gtcaaaaagt aattaccata aattttagct agagttttta
    11521 tgagtcccat attactctcc ttcgatgatt tcagcctctt ttcggattgt ttcaacatct
    11581 tcttgatatt gaacttcact atagttaact agcttggaca attctttctg caagctttca
    11641 cccatcggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc caagatagga
    11701 ataaatttcc ccattccttt ggccagccct cccttggtaa gattcacacc aaatattctt
    11761 aagacttttt tcaaaatagg ataccaaagc gtcttagtta aagctttatt aggtactgtt
    11821 ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaagcagc agttccattc
    11881 acccccaaca tgacgcctag ataaagcaag agggtatttt gagcatcttc actcaactca
    11941 tcgcgtgaag cccaaagatc ctcataacca taaatataac ctaattcttg ggccaatttc
    12001 agagagaaag cataaaattg agccacatca gctggaatgg taattgccat agcaagccct
    12061 ccaggtaatc ctgccaaaac agaagtccca ctcgctaata aaacattatc cctaatacag
    12121 gcattagcca ctcgatctaa gatttcttga gataagagag acgttggacc ttgttccaat
    12181 aaggtaggaa tgtcctgtgg acccaattct ttggaaaact tatccactaa aaatttcgaa
    12241 cgatcaacct taacaactgg tagttttacc acttgttgta atacttgcat agctaagtct
    12301 tgttcagcca tatacaaact ccttatttct tttttacacc ttatcatatt atatttccta
    12361 caaaaaaagc attttctaat tagataacat taaaaaatac agaacccctt tttttatagt
    12421 aaaatgaaac acgaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
    12481 ttagaagtag aggcgtacta ttctagtttc aatatatttt aaaagaatat ttttccattt
    12541 caaattcaac ctattttcct ccaccaaaaa agaggggcaa cccctcttct ttagttctta
    12601 tccagattgc gtagcatctc gtcaatcttg tttccatact cgatggactc gtctttgacg
    12661 aaggtcaaat ctgggatttt gtacaatttc aaattgcgac caagttcacg tttgatggta
    12721 ccagttgctt tttcaagccc gatttgggct ttttggttat ccgaagcaag gttactcaaa
    12781 atggtgtaat aaaccttggc aacagacaag tcacccagca tctgaacatc tgtgatggtc
    12841 acaccttgga cacgtggatc acggactttc ttttgcaaaa tctcattgac ttcacgcttg
    12901 atttccatgc ccacacgatc tgtacggaaa tgatttgcca tgatattcct ttctctactt
    12961 tgaaccaaaa gctaggccag cagacctagc tattttaaac ttcttgattt tcagtttaaa
    13021 ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa gtgatggaac
    13081 tgatttatca gtcccatcac aggggatttt tgagacccta ggctcaaaaa taagcaatga
    13141 aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat cttatctctt
    13201 gatttcttcc atgacatacg cctcaatcac atcatccatc ttaatatcat tgtagccgtc
    13261 gatcatcaat ccaccttcac ggccgtttgt aacttcctta acgtcgtctt tatagtgttt
    13321 caagcttgcg agttcaccat catagataac gacaccatca cggataacac ggactttaga
    13381 gtcacgggca accttaccgt tgataaccat aaatccaccg atagttccca ctttagacac
    13441 cttgaaggtt tcacggataa ctgcttcacc aataactttt tcttcaaatt ctggatcaag
    13501 catccctttc atagcttctt ccatctcttc gataaccttg tagataatgc tgtgaagacg
    13561 gatttccaca tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc gtacgttgaa
    13621 accaacgata aaggcatttg aagcttcggc aagggtcacg tctgattcgt tgatagcacc
    13681 gaccgctgag tggacgatag tcactttgac accttccacg tcaatctttt gaagtgaggc
    13741 agaaagggct tcaacagaac cttgtacatc agccttgatg ataacattaa cagatttgag
    13801 ttccccagct ttaagggtat caaagaggtt ttcaaggcta acacgttggg tagcttgacg
    13861 ttgtttcatg agggcacgtt tggcacgctc ttcacctgct gcacgcgcag atttttcatc
    13921 ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg tgatagagac
    13981 tggtgttgat ggtccagcaa ctttaacacg acgaccaagg tcgttggtca tagcacggac
    14041 acgaccgaag gtatttccga caacgattgg gtcttgaaca ttcaaggtac cttgttgtac
    14101 aagaagggtt gcgaccgcac cttttccttt atccaagcgc gcttcgataa ccgtaccgat
    14161 tgcacgcact gttgggtctg ccttgagttc ttggatttca gctacaagaa ggactgtttc
    14221 caacaattct tcgatatttt ggttgaattt agctgagatt tcaacaaatt cagaatctcc
    14281 accccaagca gttgacataa ctccatgctc tgccaattca ccgataacgc gttctgggtt
    14341 agcacctggt ttatcaatct tgttaatggc tacgatgatt ggaacgttgg ccgcttttga
    14401 gtggttaatg gcttcgatag tctgaggcat aaccccgtca tctgccgcta cgaccaagat
    14461 cgtaatatcg gtaacagaag caccacgcgc acgcattgat gtaaaggccg cgtgtcctgg
    14521 tgtatcaagg aaggtaatct tcttaccatt ttccacgatt tggtaggcac cgatatgctg
    14581 agtaatacca cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat ccaaaagggt
    14641 tgttttaccg tggtcaacgt gtcccatgat agtaacaact ggtggacgct caaccaattc
    14701 atcttcattg agataaccat cttcgacaaa gaaacgttcg atgtcagcat tatccacttc
    14761 aaccttttgt ttggcttcga taccgtaatc caccatgagg agttcaattg tttccccatc
    14821 caaggattgg ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa caatttcagc
    14881 tggttcacgt ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg tatattcaaa
    14941 ttctgttggc aattcatgga atttacgctc cgtaacaggt tttggagtct gattacggtt
    15001 gttcttgtta ttgccttttt tgttcttttt gttgttattc cagttactat tcttttgatt
    15061 tctcacttga ttttgactac ttcgattctt ttgttgtttt ctaggaccat cttcttcatg
    15121 atcataatcg tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg tatccactgc
    15181 aggttctttt ttctcaggga cgacttcaac cactgcttga acttgctgtg cttgttcagc
    15241 taacttagcc gcttcttcaa agatttcctc tggttccttg cgtttgttag cttgagccaa
    15301 ggcttcttta gcagcctgat actgcttgaa gcgttcctca cttgaacgag cgtactctgc
    15361 attttgctct gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg gagccgcttg
    15421 atttgaacgt ttgtcctctt gctgacggcg ctcatttcta cgtttttgct gaccttgctg
    15481 cttcttagct tggtcattaa agcgacgatt gtcgcggttg ctttgacctt gttttccacc
    15541 attacggcca tcgtttttct gacggtttcc gttttgttgt tggtcacggt tattgccctt
    15601 attttgcttg cgtcgttctg cctgctcttt agcacgggct tcacgctcag ccttgaaatt
    15661 acggctttgc ggtttcgctg ctactttttc tgttttcgga gcaactggct cagccggttt
    15721 tgcctcttcc ttagctacag ctggtttagc tggctcagat ttttcggttt tcttttctgc
    15781 acttactttt ggtgctgcag gttttgcttc tactttcgga gcagctgcag gcttaaagct
    15841 ggcagcaatt tttgcagcga cagcttcttc cacacttgat gagtggcttt tcacatccaa
    15901 gcccaactct tttgcacgcg ctacaacttc tttactttct tttccaagtt cttttgcgat
    15961 ttcgtacaat cttttcttag acaaatcatg tcctcctctt ctattccata agagacctca
    16021 ttttctttgt aaatccagca tctgttacag ccaaaacctt tctcgatttc ccgactgcta
    16081 tgcttaattc cagtgttgaa aacacggtta caatttctac ttgataataa tgacttttat
    16141 cttgaatctt cttggtcaga ttgggtccag catcatgagc tagaaagacc aacttggcct
    16201 tgccgtcttg aatggccttg accaccaatt cttcacccga tatgatgcgc cctgctcgct
    16261 gagcaagccc caagagatta cttatctttt gcttattcaa gtcccaactc tcttcttttc
    16321 actttgtgat ccacataagc gatcaactcg tcataaaagc tttcttccac ttccatgcta
    16381 aagctgcggt taaagacctt cttctttttc gcctctaggg cttctgcatt gtctagtttg
    16441 atataagcgc cgcggccatt ggccttgccc gtaggatcaa taaagacttg tccttccttg
    16501 ttcttgacaa tgcggagcaa atcacgctta tcaatcactt cgttagacac aacagacttg
    16561 cgcaaaggga tttttcttgt tttcatcttt ccctcctcta gcagctttta ttcttctaca
    16621 gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt ccatggcttc aaattcgcta
    16681 gcagacttga tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac gttttgtcca
    16741 cgacgaccaa tggcaagaga aagcttgtta tctggaacaa ccaccaaggc acgtttgctg
    16801 tcgttttcat caaagataac ttggtcaacc tcagcaggag cgatggcatt gtagataaat
    16861 tcagctggat ctgctaccca ctcgataaca tcgatatttt cttcgattgg taccatgcgg
    16921 tcatttttag catcgtaacg agctgggtgg aatttgctag taatcttctt gatattagca
    16981 ccaccacgtc caacgattgt accgatagca tccacgtttg gattgtggct acgaacagca
    17041 accttcgtac ggtcacctgc ttcacgagcc acgctcatga tttcaacagt tccatcataa
    17101 acttctggaa tttcttgctc catcaaacgt ttgatcattt ctggatggct acggctaaca
    17161 aagacgttca caccacgagg gttgtcttca accttgtaaa cataaacttc gatacgatca
    17221 tgagaagcaa aaacttctcc aggaatttgg tcttgttttg acaattgggc ttcgatgcta
    17281 ccaaggttga catagataaa gcggttgtca aagcgttcta ctgtaccaga catgatttct
    17341 tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg cattttttcc
    17401 atgatggttt gtttggcaga ttgggctgct acacgaccaa actcagctgg tgcttcttca
    17461 aacttgattt tgtctccaag ttcataagct gaattaatgg caagagcatc tttcaagctg
    17521 atttccaaac ggctatcaaa tacttcatca acaacttcac ggacagtata aactgtaaag
    17581 tcacctgttt tttcgttgaa gtcaatagct acgctgtctg actgaccata gcgtctgcga
    17641 taagcggaac gaagcgactc tactactgcg tcgatgatat cttctttttt gattcccttg
    17701 tcttcttcca aaatgcggaa ggcctctagc atttctttac tcatgttttc ttcacttttg
    17761 aatcctcaaa agctatcctt tctttttcta taatttaact gctaaacgtg cttttgatac
    17821 taaactgtat ggaatttgga cggttttctt acgcgtcttg cccatatatt ccatagtcaa
    17881 ctcgtcctct tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat cgatggcttg
    17941 gtagagcccg acatggatgt attttccaac cgctccagcg acggcatcct tggttttcaa
    18001 agggcgttcc aaacctggac tggtaatttc taggaaatat tgttctggga agggatctgg
    18061 cttgatggtg tctaggacag gactgataat ttctgtcaag tctgccgtgt cgttcaaggt
    18121 aattccttcg ggtttatcta caaaaatact gagaatcatg tcactgccaa tctttccata
    18181 ctcgatatcc acgagttcaa aaggagcttc tatgacaggt tctacaactt ctctgactaa
    18241 ttctacgatt gttgcgattg cgtccacctc ctcataagca agaggcgaag atatttcccc
    18301 gcctcacttt tcatattctt actatcagta tagcacgttt gccaacttat gtaaagcaaa
    18361 agcacttgta cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac tcggtagata
    18421 acttgcccct tgtttgagaa tttttgctcg tattctgtca tgacattgcc ttcaaaatca
    18481 ctggcatgca aatctaacca gacaccattg agtttcatgc catattgaga aaagctcact
    18541 aaactgtact caaacaagcc acggttatcc gtcttgaaat gaatttctcc attttcaggc
    18601 aagatacgtt tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt ttcatggcgt
    18661 tttttcggcc atggatctga aaagttcaga tacaagcgat caatctcacc gtcttcaaag
    18721 tagtcagtta agtcagaacc atctacccac aagagcttga tgttaggcac tccaacttca
    18781 agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc gatatagttg
    18841 atgtcagggt cttgcttggc catacctgaa acaaaggcac cctttccact tccaacttcc
    18901 acatgaatgg gattatcatt gccaaacaag tcccgccatt ttgccttggc ttccaaggga
    18961 ttgaggacca catactgggg atttgcctct agtaattctg ttgccccttt acgatttcta
    19021 actctcatct tctctttcca tacttgtctc ggaaatgacg caaaccatga atctcccgat
    19081 tgacattttc taaatcttgg ttcatataat acttggaaat ctgactcaaa taagacaatt
    19141 gaccatacca atacaattta cttaataccg tttgattgta cttgtaaccg tagtaggtca
    19201 accattcctt ccactgatgt tctgaaatat aatggcagag catatgggcc acatcaaaca
    19261 tgcgatcggt caagcgaacc gaatcccaat ctactaaata aatcaagcca ctatctgtct
    19321 caatccaatt actatgtcgt acatctccat ggacaatggt cgcatggtcc tctctaaatc
    19381 ctggaatagt ctgacgtaaa tcagccatca cttcactgat aaaatgattt ttacgcaaag
    19441 catctggagc cgtttcctgc caagactgta gtaaatctac aggtgtttcc atggcatagc
    19501 ccaaacgact caattgtgtc atcaacggac gtgagcgatg aagacgggtt aaaatattga
    19561 cgatttgctt acgattcata tcataggggg tcaatatctt gcctgtcaac cattcttgag
    19621 cacacatatc acgcccatct gccaaacgac gactccataa taattgtgga gcaatttgtt
    19681 ctctagctag accaggtagg attggagagg tgttcatttt tacaaagatg cgcttcccat
    19741 caggatagct acccatataa gccttgccac ttttcccagg tatgggagtc agtgttagct
    19801 cattatcacc caaatccatt tctttcctcc gtataaagtt tccttactat tctactagtt
    19861 tttggcctat tcgtcaacca ctctaacccg attctcaaag aaaagcctct ggattggctt
    19921 gggtatcatt atagcttgaa aaaggtaagc accgtcttct gcttaccttt tcataatttt
    19981 tataaataat ataagagtgg ccaactgttg taaagcatat ggactagagt agaaacccat
    20041 aggttttgac tctttttata agcaaagccc agcaacaaac ccccaagtag ataaaaaata
    20101 aacgaaggga cattagaagg tccatgcatg aaagaaaaga gagaggaagt tagcacaagc
    20161 cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat gagttcctcc
    20221 tggatggggc caaaaactga ggtagtcaaa atcaaagaca gggaaattcc tctgctgact
    20281 tccgccaagt gttggacccc tgagccagaa gaaacagcga agaaatgaat ataaaccagc
    20341 gtctcaagta cacttagaag aaagattgca atgaaaagca aaagttgttt cttgcttaac
    20401 atcccaaaag aaatcatttc aaactttcta gcataagcaa cactcagcga ggttacaaga
    20461 agacttacaa gaatcaatgc agattcattt tgaaaaaaac ccccatggtt aatcgtataa
    20521 ggaactgtaa tgacaattat tagtactaaa aatccaaaac acaaggcatg aaatttatca
    20581 aaaaactcca taaaattatc ctcctcaaca aacagacttc ctacacgtca ttctttagtt
    20641 ctagcctttc caaaacaaac cattttatac tcttcgaaaa tcaaattcaa accacgtcaa
    20701 cgtcgccttg ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt
    20761 tcattgagta ttagtaacca aaatccgacc acatagccag cccctatgaa tatagccatt
    20821 aaagctagca tggaatttag gaaattaaaa accaccgcag atacaaaggt tagcacaaaa
    20881 acattaaaag caatggtgtc agaagccaag actagaatat agggtgtcaa ccgatctaaa
    20941 gttttggaat ctaggaaaaa taagtgttta tacatgatga cctcctctat ggctgaaaag
    21001 caagcctttt gtttttttac cccaagaccc tatgtagaaa agtgagcaaa aacgggaagg
    21061 tcgctacaat attattgatc acatgcaccg cataggatgg ataaatgctc ttggtatagc
    21121 gggtcaaacc agcaaagatg attccaactg ttgcaaagac gaagatatct aacagactag
    21181 gcaggcttga aaaatgaggg agagcaaata aaatagaagg aagaagcaaa tcaagaccaa
    21241 atcgcgaatg cttaaagaaa gcatgttgca gtaatcctct ataaatcaat tcttccatca
    21301 gtggaaccag aaagaacagg gctatataaa tacctagctc tgcaaagtta gtcccactat
    21361 aaccaatcaa tacagcccaa ccttccgcag ttgactgaac atgtttagct gtctgaacgt
    21421 taaaagagat ctggaacact accactaata ctgtcaaaat cgaataccaa agccattttt
    21481 ttcttggaat gcggaagaga taaccatggc ctgtcttaac aagaaccaca atcatgactc
    21541 caataaaaag taaactcaag atattttgaa tccagaataa attgcctatc tgagaagaaa
    21601 attgccaata gttttggacg ataagcgtca gctgagaaag accaaatacg aaaaataagt
    21661 aagagaagac tgcacttatt ttgaatagaa gttgatactt tttcatagaa atcctcccta
    21721 ctataacctc accttgtcag gctctactgc tgtaagatta agaagacagt ttgttttttt
    21781 taaggctaac ctgactacta gataatagat acattaaggc attaaagaca atgaaaatat
    21841 gtccatagaa taaaatcaac ctcgcatcca aaccaagata aagtttgatt atcaaaaaga
    21901 tgagcaaaag aatttgaaac cataaggttt ttccaaaaat aaatttaaag cgatttcgaa
    21961 tatctacttc cttgattttt accgccaccc ctttattagc aagaaggaaa actcctgctt
    22021 caaacaaacc actgtaaaga acaagccacc caatagatac gatagagatt tgtaaaaatg
    22081 tccctaaaag aatatccaac acactactca agaaaataac aaaaaataat ctgtatttca
    22141 tattaaatac ctccattcat ttatttcact aacaatttaa tagagccttc tactcaaata
    22201 tcctgtcaga aaaggataga aagctacttt ttataatact tcaagcccca catgagcaga
    22261 agcgtgataa acaagcagag aatacaccta tataagcgat tagttgttga tagaattctg
    22321 tttctgaaat acctctatac aaacaaatga caaacataaa atctgccaag ccgataaaca
    22381 taagttgatt ggttctagga ctaaccaaat catcatttac ttatatttaa gagtatctct
    22441 tttatgttag tgtatgttaa cactaaaaaa caagttaggc caataatatt taaaatgaac
    22501 aataacgggg ttaagtctct aaaaaaatta tctactgaca ctacaagaaa tactatacat
    22561 attatagtcg aaactatctt tttcttatcc ataattattt actcctttcc taacaaatcc
    22621 aacttatcaa tcaagagcga tttttaacat aatgtagcag cacccgttgc aactttgaca
    22681 agtttagtat atcattgttt tttaaaattt ttcatccaaa tcttgaattg tcatcgaaac
    22741 ctcctaaatt gcaaaaactt cattagcccc tactttttat aatacttcaa accccaaatg
    22801 agtagaagca tgatgatcaa gcaaagaata gcaccaatat aagcgattag ttgttgataa
    22861 gattctcctg ctgtgatacc tctatacaaa caaataatag acataaagcc tgtcaagccg
    22921 ataaacatga gttgattggt tctaggacta accaaatcat cgtcttcaaa ctcttttatc
    22981 cgcatttccc tagtgaggta aacagtgacc aaaatagaag ctaagttaat aaccactaaa
    23041 agaaattgga aaactgacga aatagaaata gataagtaga aacaagcaaa ggcaactgcc
    23101 ccaggaacaa tctcacaaag aatatgattc tttttaatca agaaaatctt tcatttcttt
    23161 tctttctttt taattaaaga aaaatagatc ataaccgcaa tcatataggc tatggtataa
    23221 aatagattat accaaatact ctccctaagc ggataaagaa agatggacat gatcagatac
    23281 agaacgaaaa taatcagtat ttttttcttc ataagatttc ctcctaaatg tgcgatttat
    23341 cttagttgag caagaacatt tacactgcta gtatagcact tattttgacc ttggatcact
    23401 caaatcataa atggtcatca aaacctcttg aattgtaaaa attaaaaaaa gcaagcatga
    23461 aaaacatact ttcctcttta tgttgtattg ataccaactt gtttgtagac ttttcatcct
    23521 gctatcacat atcattttga caggcgaaac aatattaaag aaactcccct gtaaattaag
    23581 ctagcaaata caggggagaa atttattttt tagagagtac tatccgtatc ctttttggaa
    23641 gattttgaaa atatttttct aattaagtca tccatataag gaccaaatat accaactact
    23701 aaaccaataa taaaactttt aaaatccata attaccacca acatgttgct acataggcta
    23761 cacctccaag tatagctcca cctgcagcac cagttacacc tattcctata gcaaatggtc
    23821 ccaatagaaa tgtcaaaccg ttgttgcaca cccatcaatt gcgccatatg caacccctgc
    23881 tgcacaacta atttttcttc cccaatcaat atctccacct tcaacgcaag caagcatttc
    23941 attatccata acagaaaatt gtgacatcat ttttgtattc atatagtatg tcacttttca
    24001 gttacggaac aagtttaata taaaaattat caaaaaaaca taggcaataa agagaaaaat
    24061 taatttatca tagattagaa ataatatgac aaaacaattc aatgatgtta attcaatagt
    24121 cttttgtttt ttatcagaga tacttatgga tagataaata agataggttt gaaaagcgaa
    24181 gagaataata aagaatatag ccttcataaa atttagcttt catttttatg atgtagcggt
    24241 ataggctaaa tatccacaaa ccactgctcc tccaattcct cctattgcag cgccccatgg
    24301 tcctagaatt ttcccatatt tcactccacc cgctgcacaa cctaaagcag caactacagc
    24361 tgctcctccg gaattacctc cataaacctc actcagcatt gtttcattta tattacaata
    24421 agtattcata caagtctcct tttattaaaa tccacccgtt gcccctgtta ctcctgccca
    24481 aagatccaca ccaaatttag ctcctatgta tccacatgct cccataaatg gtgctccaac
    24541 accactcgca gcacaaatag ctgtccctag cccccagcca ccaaaagcag caccaccacc
    24601 ttctaagaca ttagtttgcc aattattctt gcctccttca atactagata acatagttat
    24661 atccatttca tgaaattgtt ccatcatttt tgtattcatg acaaatactc ttttttattt
    24721 ttaatttttg tcttgttgta actttgacaa gtttagtata tcatcgtttt ttaaaatttt
    24781 tcatccagat cttgaatagt catcgaaacg tcttgaatta gcttttcatt tgaaaccacc
    24841 tctaaatttt ttaaaaaaag ataatttcta attatttttt accattcagg aagtttcaat
    24901 gactattcaa gatttaataa aatatgaact tatttttatg gcataatata cctatctact
    24961 atatgaaagg aattgccaat gacttcttat aaacgtacat ttgttcctca aatagatgcg
    25021 agagactgcg gtgttgctgc cttagcctcg attgctaaat tctatggttc agatttttct
    25081 ctagctcact tgagagaact tgcaaagacc aataaagaag ggacgactgc tcttggcatt
    25141 gtaaaagccg ctgatgaaat gggctttgaa acaagacctg ttcaagcaga taaaacgctc
    25201 tttgacatga gtgatgtccc ctatccattt atcgttcacg ttaacaaaga aggaaaactc
    25261 caacattact atgttgtcta tcaaacaaag aaagactatc tgattattgg tgatcctgac
    25321 ccttctgtaa aaatcactaa aatgtcaaaa gaacgctttt tctctgaatg gactggagta
    25381 gctatttttc tagctcccaa acccagctat caaccccata aagataaaaa gaatggtcta
    25441 ctaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat tgttctctca
    25501 agcttattgg tcactattat caatatcggt ggttcttatt atctccaagg aatcttagat
    25561 gaatacatcc caaatcagat gaaatcaact ttaggaatca tctcagttgg tctggttatc
    25621 acctatatcc tccaacaagt catgagcttc tccagagatt aagcattgat gtgattttat
    25681 cctatattcg ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag
    25741 aaatcatttc acggttcaca gatgctaact ctattataga tgccttggct tctaccattc
    25801 tttctctttt tctggatgtt tctattctga ttcttgtagg gggcgtctta ctggcacaaa
    25861 accctaatct cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt
    25921 cttttatgaa acctttcgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta
    25981 gctctgccat tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag
    26041 aaaatcgcta tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc
    26101 tcagtaaata ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata
    26161 tccttatcct atggtttggc gctcaattag tcatgtcaag taaaatttct atcggtcagc
    26221 tgattacctt taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc
    26281 tccaaaccaa actccaatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag
    26341 tcgaatctga atttcaagtt caagaaaacc ctgttcattc acattttttg atgggcgata
    26401 ttgaatttga tgacctttct tataagtatg gttttggacg agatacctta acagatatta
    26461 atctcacgat taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa
    26521 caactttagc caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca
    26581 atcatcagga tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac
    26641 cccaacaagc ctatatcttt aatggctcta ttttggaaaa cttaaccttg ggcggtaatc
    26701 atatgattag tcaagaagat attctaaaag cttgtgaagt agctgaaatc cgtcaagaca
    26761 ttgaaagaat gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag
    26821 gacagaagca acgaatcgct ctcgctcgtg ctcttttaac taaatctcct gttttaatac
    26881 tagatgaagc tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta
    26941 tgtccctaac tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa
    27001 ccaaccgtgt cattgttctt gaccagggga aaatcattga agttggtagc caccaagagt
    27061 taatgcaggc gcaaggtttc taccatcatc tattcaataa ataaggagaa tgtcatgaat
    27121 cctaatcttt ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg
    27181 ttaattatac ctctttcatt actatttact ttcatcttga ttttctccct tgttgccaca
    27241 aaagaaatta ctgtcacttc ccaaggagaa atcgccccta caagtgtcat ttcatctatt
    27301 cagtcaacca gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa
    27361 aaaggggact tactcatcaa atactctgaa acaatggaag aaagtcagaa aactgcctta
    27421 gcaactcaat tacaaagact tgagaagcaa aaagaaggac ttggaatttt caaacaaagc
    27481 ttagaaaaag cgactgatct tttttctggc gaggatgaat ttggctacca taataccttt
    27541 atgaatttta ctaaacaatc ccatgatatt gaactgggta tctcaaagac taacactgaa
    27601 gtttcaaatc aagctaatct taccaatagc agttcatcag ccatcgaaca agaaattaca
    27661 aaagttcaac aacaaattgg agaatatcaa gagctgagag atgctatcgt aaataaaaga
    27721 gctcgcttac caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct
    27781 caagaacaaa cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt
    27841 gcaggtctgg aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta
    27901 gcaacttatg ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa
    27961 acagcctcac agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta
    28021 gatcaagcga cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt
    28081 catctgaaca gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa
    28141 atattccctg tcatcacaga tacaagagaa gtactaatca cttactacgt atcttctgac
    28201 tatctacctc tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat
    28261 cacggcacca ccatcatcgg ccaacttcag acaattgatc aaactcctac cagaacagag
    28321 caaggaaatc tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc
    28381 atccaatatg gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat
    28441 tatttcaaag ataaaatttt aacccattct gattaatttt cagataacac tctataacta
    28501 tttattatct tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat
    28561 ttcaagaact aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt
    28621 tcttatatag atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac
    28681 aactataaaa aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat
    28741 atgtattaca gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt
    28801 attgggatga ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc
    28861 tttagaactt gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga
    28921 attttcaatg ataaaggtct cctgtgctcc atttttaaaa aaggcaattg aaacatgagg
    28981 ttgacaggct tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag
    29041 aaaatcaagt agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac
    29101 aatgttctta tctctagctt ttataaattt tccagctagg agacttttga gggcacgatc
    29161 ccgaacattc accaatcggc caaggtcata tttattgtcc tgcaatttct gactggaatc
    29221 ccttaagacc gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccaa
    29281 acgtaagctg gttaagaggt tagtgtagtc atggcgaaaa ctccgaattt ccttgtaaag
    29341 ttcctctata tgccgactat agcgttccat atctctgtag cgcaaggtct gctcttggtt
    29401 cagttcctcc tgaagttttt ccttcaaata ggtatccaat ttcttgatac cccccataaa
    29461 aaagagtagg taaaacacta ggatgagatg gcgaacagtc gttgattgaa taccttgttc
    29521 atattcaagg taagatagac tttgcatcac tagataataa gcccccattg cccagttaat
    29581 cttagtaaga gacttttgaa aacctgtatc tagaaactcc cttctcaatc tagtgaaatc
    29641 atagtctaac catttcaaaa agactaaaac tatgaagcaa acgaatatca taatcaataa
    29701 aaagatagga ttgccatccc catctacaat tccttgcccc aaaaatggaa gcacaaaata
    29761 ggaaacacct ctgtaaaaga gctctactaa tatcattggg aagagaccat aaaaaataag
    29821 gattttttta ggaagccctc ttaacaataa gaaagataga cctataccga acaaaggttc
    29881 tataaaatag gacaaatatt tacttacagc caaaaattga aaagtcgtaa aaatgatccc
    29941 tagaagaaat ttcagaagaa aggccttaaa aatcctctcg aaagtaagat caattccatc
    30001 caccttaaag aagatgacaa tttctagtcc attagtaaca agtgtataca acaatatcca
    30061 agcaatgttc ataaattctc ctagctcagt gtaatttatt gatggcctca gacacttccc
    30121 tgaccttata acgggcgatt agacaacttc caccattggg aaagaaaagc agtttttctt
    30181 tcttatccaa atgcaccaca tttgcaggat tgatgagaaa agagcggtgg cactgcaaga
    30241 gacggggctc ctgcttgaaa acctcctcta aactcgctgt aaattccagc ctgtctgtct
    30301 tggtatagag aataacacga tgggctctgg gcgacgtttc gagatagtaa acctctttaa
    30361 aaggatactg aaattgggca aattttgatt taaagtaaaa gcaatcttcc gccagacttt
    30421 tactatcttg actattggca tagaggaggg ctgtctcgat ccgagattca aactcctctg
    30481 ctgacaaggc cttatcaatg tagtccaaag cagacacttg gtagcgaaaa gacaggggca
    30541 taaactccga gtgagtcgtc acaaagacaa tcagggcata aggatcccga tcccgaatct
    30601 ttctagccac ttccagtccc ttcatctctt catttcgaat ctcaatatcc aaaaagaata
    30661 gctgatgggc ccccttctca tgcacttcag ccagcagttg gtccggcttg ccaaatacct
    30721 caaaagagct aggaatgata tgatgtgctt tcaaaagttt ctcaatcgtc gtttcaattc
    30781 tagtctgttg ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct
    30841 ttcaaccatt tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga
    30901 ccttcttctc cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga
    30961 ttaaccaaac aatttcgatg acatctcatc aaggtttccc cacattggtt ctcaagatta
    31021 cttaaatttt gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct
    31081 ttagttggat gtgtttggat atagtagata tcgtcgatgt ttactttata gactgttttc
    31141 tgcgtctgaa taatcatata tttcattgga ttctcctcct aagaaaagaa taacagaaaa
    31201 ggtctagccc aagcacaccc aatcctaaac agtctttgaa aactcctaaa aggattattt
    31261 tctacaacat catgatgagc ttacaactat tttatcataa aattcactca gcgcaattca
    31321 agacatttca atgacaatta aagatttgaa taaaaaaaaa gaattaaaag tgataaacta
    31381 acagtatcaa aacacagttg ccagaagtaa gactggcacc cagattaaag gaggcattcc
    31441 catgacagat acagacccca tcaaaagagc tcatactttg attactgact taaacaaagc
    31501 ctaccaagca tgcaaacagg caagcgctga cgacgtccgc tttcaggagc aattaaactc
    31561 tattcttggt tttctagcca aggctgaaac agtggataat cgattcttga ttgaactaga
    31621 aaaattttac cagacttcca gtcttctcat gggactcagc gctcttgatc cagatgctcc
    31681 aactcgcgcc gcttggcggg cctatgaccg cttccacttt gaccaagtca agaccaagtt
    31741 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaagctgt acttgagtac
    31801 ggtaagacga cgctgacgtg gtttgaagag attttcgaag agtataagtc tctacggacc
    31861 aaccattatc ctgtagtaac aaaaaagaag ttgagacaga ctgaactcaa cttctttttt
    31921 agtgtcgtat cagcaatgtt agtcctgcat ctgacgtttt acctgataag gcaaatacaa
    31981 gactagtaaa accaaaccag ctcctagtaa ggctagaagg gctagttttt cttggaaggt
    32041 aatcaaccca acaactaatt ccacaagtaa aacaaaactg gtcaatcctc gaactacctc
    32101 ctgtaagcct ttttcctttt gccccttgtc cagcggaaag agttgggtca aatactggta
    32161 gtcaaaggca tgatagaggg ccagcaactg gaagagcaag aggtagttaa agagaactac
    32221 cactgctgtc gcaatccaag cttgctcgat aaaaacctgc gccagtacgg aaagtaagag
    32281 aagacgaaga ctgagagcaa agaggtcgcc atttcgcaga taagaacgca gatagagatt
    32341 ttgccaaatc ttcccaggca ccttctgaac agcctttaag ataaagtcca gataggcacg
    32401 acgcttaacg ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga aacgaagcaa
    32461 gacttgctta cgcttgcttt cttgggaaat gacatagtcc cagtccagcc cagtttcagt
    32521 gaaaaatttg ctggcctttt gacgaaagtg gaaatatttt cctaccccca ataaaagcac
    32581 atagagcaga aaaactggca agccataacc cattgctaaa aataaaggcg caaataacag
    32641 caagaaaagg gtctgtacaa agagccaaaa gactagggaa atgccagttt gacgcttgag
    32701 atggagcttg atttcctctt ctccaactaa gagaaagagc ttgtctggag cctccatata
    32761 ggtggcaatt cctccccaaa gtaaaagtaa aacagacgta attcctacaa acaaaaggat
    32821 aggccaatga ttttcaggaa aatgttgtaa gagttgactg tactggtagg ctagaaagcc
    32881 caacaggaca agcaggaaca agacaaagtg gtcattgagc acatagcgca gataaccaag
    32941 acactcctta cgaaaggcct gctttctctt taaaaacaag tctttcatag atcctcctct
    33001 ttggtcagag ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa ggcttcacgt
    33061 agttgcagga gattgccttt ggcacgcacc tctcccttgt gaagaatgac aaaggcatca
    33121 cacatcttct ccgccgaatc cagcacgtgg gtactcatga gaatagactt gcccttttgc
    33181 ttctccactt ccaaaagctg aatcaaatca gaaatagcca gcggatcaag accaaggaaa
    33241 ggctcatcca cgatgaaaag acttggatcc accacaaaag cacagataat catgaccttc
    33301 tgcttcatcc cttttgaaaa atgaacaggg aaccagtcta atttctgttc caaacggaac
    33361 atttttaaca agggctctac tcgttcgaaa gccacttttt gctcaatacc gtaagccata
    33421 gcaaccgttt cgatatgctc tctgagggtc aattcctcat acagactagg cgtctcagga
    33481 atgtagccaa tctgcttgcg gtagctagtc gcatctcctt gcagagtcag gccattgata
    33541 ttgatggagc cactataagg tgccaacaga ccgataatct cattgatcgt cgttgatttc
    33601 ccagcaccat tgagaccaat caaaccgacc aactgcccac tttcaacagt aaaggacaca
    33661 tctttcaaaa caggaacatg aacatagcca cctgtcaggt ttttaatttc taacatattt
    33721 tctccaaatc tggtataatg tagctatatt atatcaaaat tcagtacagt agaggtagat
    33781 tttatgtcag attgcatttt ttgtaaaatc atcgcagggg aaattcctgc ttcaaaagta
    33841 tatgaagatg agcaggtcct tgcctttctt gatatctctc aagtaacact aggacacacc
    33901 ttggtcgtgc caaaagaaca ctatcgcaat cttttggaga tggatgctac gagcgccagc
    33961 caactctttg cccaagtacc aaaagtagct caaaaagtca tgaaagtcac taaggctgct
    34021 ggtatgaata tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt tcatactcac
    34081 gttcaccttg tgcctcgcta cagtgctgac gatgacctca agattgattt tatcgcccac
    34141 gaaccagact ttgacaaact tgctcaagtc gctgaaacca tcaaaaacgc ttaaggagtt
    34201 gctatgaaat tatccaacct actgctattt gcaggagctg cagccggaag ttatctggtt
    34261 acaaaaaatc gccaaaccat cacagatgaa gtcttgaata ccactgaccg cgttcaagct
    34321 atcaaggacg atgtggatat tatccaaaac agcctgcaaa tcattaacca gcaaaaagaa
    34381 cttatcaagg aataccaaga agacttgact tacaagttta aggtcttgga aaaggatatc
    34441 cagactagac tagctgtgat aaaagaaatg cagggaactg aagataagta aaaagagccc
    34501 gacggctctt ttttaaaacg taaacaagtt atagtgaatt gaatttagaa tagcacatca
    34561 tagtttctaa agcattgtta gagattactt taaaatcctc ttatcaattt gttcatattc
    34621 tatttcaatc tactatatat atcccatcaa ctatgcatca taatttaggt aactcatact
    34681 caataaaaat caaaaagcaa actagaaagc taggcacaga ctgctcaaaa caccgtttta
    34741 aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa
    34801 ctgacgaagt cagtaaccat acccatgaca agccgacgct gacgtggttt gaagaaattt
    34861 ttgaagagta tcattcacca tttcacaact aaatcgaaga ctttctgccg taatgaaaac
    34921 acctgaaaca gcttggtttc agctgtccgg aaactttaag acttaggttc aaagtttagg
    34981 tatggaactt cgaaggaggt cgctaccgtc cgtcattact taggaaagtc ttaaaaaatc
    35041 tataaagtaa aaagagcccg acagctcttt ttgtttatac tcaatgaaaa tcaaaaagca
    35101 aactaggaaa ctagccacgg gctgctcaaa acactgtttt gaggttgtag atacgactca
    35161 catatatacg gcaaggcaac gctgacgtgg tttgaagaga ttttcgaaga gtattattct
    35221 ccatcaaagg catcttttat atggtcaaag aagccttttt tctttggatt tactttcaag
    35281 tcaccagcag tcgcgaattc tttcaaggct actttttggc ggtcgttcaa gcctgtcggt
    35341 gttacgacat taacagtaac gtattggtca ccaactgcac cgccacgaag gctcggtgcc
    35401 cccttactac gtaggcggaa tttcttacca gtctgagttc cctctggaat aaccaattca
    35461 acatcaccgt gaacagttgg aatatctact gtatcaccaa gagccgcttg gacaaagttg
    35521 aggttgagat tgtagaagat agtcgttcct tcacgttcaa acttgtcgct agcttctaca
    35581 gaaactacta catacaagtc accataaggt ccaccgttaa agcctgcttc accttgacca
    35641 gcgaggcgaa tttgttgacc tgtttccaca ccagcaggga ttttcacatg tacgctatga
    35701 gcttgtttct catgacctgt tccatgacag gttgtacatg gatatttgat ttcttttcct
    35761 cgaccgtgac agacatcaca ggttacttgg cgacgcatca taccaagagg agtctgcgta
    35821 tcgacgttaa tgacaccagc gccatgacag cgtccacaag tgactggact tgtccctggc
    35881 ttagcaccag agccattaca tgtacgacag ccagcttcac gatgatactt aacttccttc
    35941 tcagttccga agatagcttc ttcaaaggtc aaattgacac gatactggag atcatctcct
    36001 tggcgaggag cgtttggatt gcgcgaagaa ccgcctccgc cgaagaaact tgagaaaata
    36061 tcctcaaaac caccgaagcc acctgcccca ttgaaaccac cgaaaccacc agctccacca
    36121 aaaccaccat tggcgcctgc agcaccatac tggtcatagg cagcacgttt ttggtcgtca
    36181 ctcaaagtct cataggcttc ttgaacttcc ttgtacttgt cctcagcacc aggctccttg
    36241 ttgatatctg ggtgatattt tttggaaagc ttacgataag cctttttgat ttcgtctgcc
    36301 gaagcgtttt tggatacccc cagacgatca taaaattcag tattgttcat acaagatacc
    36361 aagaccgtaa aattcgactg aaaaatagga aatctgacgc tggagcgacg ctcctagaca
    36421 gatttctctt ttttccgaga atttaggtcg ggttcaattc ctttctttta tattgatgag
    36481 ataatactcc agccactcgg ccctatccct ttttaccgaa aaacagaggc tgggttgcaa
    36541 cctctgtggt tagattattc atttgaaata aaaatggttg tattatctct agtagtaatc
    36601 ttcaaagacc ttttagctaa atcaaactca aatttattat agtgtgggtc ttgtgtttta
    36661 tataggtgta actcctgaca tatatgatcc gaaaagtaaa tcataacatc tttaaacaca
    36721 gaagtgtggt catatttact cttaccaaca gctacttctg taaattcttt ataaatgaca
    36781 tttccatttc tttccacagt caccagcatt tctgttggat tataatccaa attaaataat
    36841 tattcaaaaa aactttatct tttcatgata atctgcaatg tcagaaagat tatttttatt
    36901 aacactcata acactagccc cttatttttc agtaaactct ccgtctacga cgtcatcgcc
    36961 tgcgtttcct gttgcttgtg cgccttctgc tccttcttga gcttgttgcg ctgctgcggc
    37021 ttgttcgtag agtttcacag caaggccttg agctttttcg ttcaacgctt caagtttcgc
    37081 tttcatgtcg tccaagttgt tgtcttcttg agctttctta aggtcatcaa gggcagcttg
    37141 ggcagcgtca cgttctgcgt cgaagccttt accttcagtt tccttgattg tcttttcagt
    37201 cgcaaagatt gcttggtcta cttcattacg aaggtctact tcttctttac gtttcttatc
    37261 ggcttcagcg tttgcttctg catctttcat catgcggtcg atttcttcgt cagtcaaacc
    37321 tgagttcgat tggatgacaa tagtttgttc tttttgagtt ccaaggtctt tggccttaac
    37381 agacacgata ccgttcttgt cgatgtcaaa tgttacttcg atttgaggaa ttccacgagg
    37441 tgcagctggg atatcagtca attggaagcg tccaagagtc ttgttatctg ctgccattgg
    37501 gcgttcacct tgaagaacgt ggatatcaac ggctggttgg ttgtctgctg ctgttgagaa
    37561 gacttgtgat ttagatgttg ggattgtagt gttgcgatcg ataagttttg taaatactcc
    37621 acccattgtt tcgataccaa gtgacaatgg cgttacatca agaaggacaa cgtccttgac
    37681 atcaccagta atcacaccac cttggatagc cgcacccata gcaactactt catcagggtt
    37741 tactgatttg tttggttctt taccagtttc agctttaaca gcttcaacaa cggcagggat
    37801 acgagttgaa ccaccaacaa ggataacttc gtcgatttct gacaagctca aacctgcatc
    37861 tgaaagggct tgacgaactg gaacttttgt acgttcaaca aggtcacgag tcaaatcatc
    37921 aaatttcgca cgagtcaaag tcatttccaa gtgaagaggt ccagcctcac ctgcagtgat
    37981 aaatggcaag ctgatttgtg ttgaagttac accagaaagg tctttcttcg ctttttcagc
    38041 cgcatctttc aaacgttgca ttgccatctt gtcagtagac aagtcgatac cgttttcttt
    38101 cttgaattct gctaccaagt ggtcaatgat tttttggtca aagtcgtcac caccaagttt
    38161 gttgtcccct gcagttgaca atacgtcgaa gacaccgtca cccaattcaa ggatagagac
    38221 gtcgaatgta ccaccaccaa ggtcaaatac caagattttt tcttctttgt cagtcttgtc
    38281 caaaccataa gcaagagctg ctgcagttgg ttcgttaaca atacgttcta cttcaagacc
    38341 agcaatttta ccagcatctt ttgttgcttg acgttgagcg tcgttgaagt aagccggaac
    38401 tgtgataaca gctttggtta ctttctcacc aaggtagtct tcagcgtagc ctttcaagta
    38461 ttgaaggatc atagctgaga tttcttgtgg agtgtattct tttccatttg cagaaacttt
    38521 ttcagaagtt cccatcttag atttgataga gataactgta tctgggtttg tgactgcttg
    38581 acgttttgca gcatcaccaa cgatgatttc tccgtttttg aatgagacta cagatggagt
    38641 tgtgcggttt ccttctgggt ttgcgatgat tttgctttca gttccttcaa gaactgcaac
    38701 tgctgagttt gttgtaccta agtcaatacc gataatttta gacatgtgtt tttctccttg
    38761 ttagttaatt ttctattttt ctttttgata ctcttcttaa gtggcgacgc cgtcagagct
    38821 tgacttcgtc aatctctttg actaaacttt gagcctaagg tctcaaaatt tgcgcaaata
    38881 gcaccacggc gaagagtatc gtctttggtt cgcttcgctc actattacaa agccaaacat
    38941 attttatctt tcttcatagt ttattgtcgt ttcggacaag ttttctatta tgtaaattgc
    39001 gacacgagga gtcgaaatcg attttatttc gacgacgagt tagtaaggaa gctaggcaaa
    39061 cgtcatagcg attgccgttt tctgacgagt tgctttagct accgtcagaa ttgccgaatc
    39121 gaacacgccc taagctctga gtaaaaaaga tagattttct tgtgttcatc gaacacttcg
    39181 tcaatctcct atttttactg cgagcttttt acgagctttg tatcttagtt atacaccact
    39241 accattgctg ggcgtaggat gcggtcatgg agtttgtagc ctttttgaaa gacttgggcg
    39301 atggtatcta ctgggtgttc atcgtctgct gggagagttt ggatggccat atggtagtta
    39361 tggtcaaatt cgccatctgc tgcgatttct tcaattcctt cttctttcaa agcgtgaatc
    39421 aagctttctt gcaccatcgc caagcccttc ttcacatcat ctgtcaaacc ttcaactgca
    39481 agtgcacgct caaggttgtc aagagatggt aagattgctt ttgccaagtc ctggctacga
    39541 taacgttgca agttttgacg ttcttcattg gcacggcgtt ggatattttg catttctgca
    39601 tgagcgcgaa gatatttgtt ttcgaactca tctgcacgtt catttgccaa gtccaactca
    39661 gacttttcag gagttgtttc ttcagctgtt tccacaactt cctcttcttg aacttcttct
    39721 acttcttcat tttttatatc ttgggccatg ttcgcctcct ttaatgattt caatcttaat
    39781 gtacttcgta atgattactg ctgaggtagc ggtaaaaatc tgtcaacttc atggtcaaaa
    39841 cacggttgac cacattgact tgattgatta gctgttggta atccagatta actggaccga
    39901 taatggctag aattccaact cctcgataag gaatgaggaa cttactacta atcaccgcta
    39961 ggtcagctaa acaggactct tgaccgtctg caacacgaac attttgcatc tgatcctcac
    40021 gcaacccctc acgaatctcc aaggccacct tttgcggttg gtcaaagaac tgataggctt
    40081 ctagattggc aaaattcaag agattgacct tgcccgccat cacaatgttt tcgttgaaca
    40141 tttccttaaa gatgtgttca aagagatcga tgacattatc cgttgttgta aagtaacgct
    40201 ggataatctg cggaatctcc gtccgaatct tgtagtgaat atctaaaacg gtgtgaccga
    40261 ggaaacgttc ctgaatgatg ctcttcagtt tcagcaaatc ctcctgcaag aagttccttg
    40321 gaatcagaaa ctgactagta accgttcgcg actcgtctag ggtaaatacc gccaaggctg
    40381 tatgttgccc caaaacaacg atatcaaagg ctgtcaaacg ttgcctgctc ggctcaacat
    40441 ccagtgccac taccgtacag ccactcaggt ctgttagcaa gttagcagcc tcttgcagaa
    40501 tatcctccaa tttgaagaat tcctgatcaa aggctttgac aatctcatat acctcatttt
    40561 cagccagccg gtgaaaatcc agtgagtgtt tcacatagta ctgaaaacca gcaacacttg
    40621 gcatccgacc gcttgaagta tgagccttct caagcaaccc ttgtttttct agttccgcca
    40681 tgtcattacg aatggttgca ctgctagagt taatagactc ttgcaaggct tttgatccga
    40741 caggttcgtg cgttttggta aagatgtcaa taatcagatt taaaatatcc tgctgacgct
    40801 ctgtaaccat ctcatcactc ctctctgtct gatcaattag cactcaatgc atccaagtgc
    40861 taacttatga ttctattata cacccttaaa agagaatgtc aagacaaaaa ctcaaaaaat
    40921 tagcactctt ttatcaagag tgctaaaaat caatctgaag acctagaacc ttgctattca
    40981 tctactcgat atttcctttt tagtctgaaa taaccatgaa ttagataaga aatcagaaaa
    41041 gcatataaaa caaaaataag aaagaaagac atagaaagat cctctctaaa caaactcgta
    41101 caaacaacaa gaccacctaa gaaagtagtt gtacaggaac gaagtctaga tcgcataact
    41161 tcccatttga gccccttact catatagact tgatcctctg gaagtaaatc agaagacgat
    41221 ttacgaagaa tcgaacaaga acctgctcct atcaattccc aacctctatc tctaaaatct
    41281 tgcagttcat gcttatattt tttaagaaat ctagaatcat agatacggta gatgacatcg
    41341 tctggttgac attggtcaaa atagaacaaa ccaaaacgac tcgttctata cctccaacct
    41401 ttcaaatgca tctcatgtaa atattcttct tacttgtcca aatcaacaat ggtgaaaatc
    41461 cgaaattcta ctctgctatt cattgtctta ccccaaaatt agaaaacatg cctggcgtta
    41521 tttattagat aattctttcc acttttgact caatctccaa aaaatataag aaatctgaat
    41581 cgcaaaaact atcaataaaa cccaatctat tatgaaaatc aaaaacactt tccaactgaa
    41641 agaactacct ccagtgacaa actttgagaa aaacggtagt agagctaaaa agagaagtaa
    41701 aataggaagc atccgcattg ttaaaatccg tttggcataa aaaaatcttt atttaaacta
    41761 aaatattata tcaaaattta cgccagtttt tgaacggctg atgtagatat tttatacttt
    41821 caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc gactgaaagt
    41881 gcttatagaa tgataataag tcgcctgccg aaaacagcgg aaaatagcgg tgttatgcgg
    41941 agataatctg acgcgatgcg aaagtatatt gcatacttat tttcaacaat ttagcagagt
    42001 atttttataa gtgtgatata atagaagtat aatttgttct gatagtttat tttatggaga
    42061 agtagatttt tagaatgcgg agggttcaat atggttgagt ttataaagtc taagaaagaa
    42121 atgagtgagg aggatattaa agcaaatttc atcactcctg ctattgtatc caaaggatgg
    42181 aaaaatggtg agcatatcgc ttacgaagaa tacttcactg atggtcgaat tgaggttaga
    42241 ggagataagg ctcgtcgtaa agaaggaaaa aaatcagact attcactgta ttaccaattt
    42301 ggaactcgaa ttgcaattgt tgaggcaaag gataataaac acagcgttcg agcaggatta
    42361 caacaagcta ttgaatatgg agagatttta gatgttccat ttgtttattc ttcgaatggt
    42421 gatggcttta ttgaacacga ccgtatcacg agagaagaac gtgagctgga gttagacgaa
    42481 ttccctactc gtgaagaatt attttctcgt atgacgaagg aaaaaggatt gacgtacgaa
    42541 attacagaag ctatctcaac tccatactat acagacgcct tctcaatgaa aacgccacgc
    42601 tattatcagc aaatagctat caaccgtact attgaaacag ttgccagagg acaaaaacga
    42661 gtaatgtttg tgatggcaac aggaacgggg aaaacgttca tggcttttca aattattcat
    42721 cgccttcgaa aagctggttt ggctaaacga gttttattct tagcggatag aaacatctta
    42781 gtagaccaaa cgatggctga agactttagg ccattcgaaa aggtaatgac gaaaattaca
    42841 ccaaaacttt tgactgctcc tgaaaaatta aattcttttg aaatttatct agggctttat
    42901 cagcaactaa ctggtgaaga tggaactgaa acacattatc aaaaatttga caaagacttc
    42961 tttgatttaa tcgtaattga tgaagcgcac cgtggttcag ctaaggaaaa cagtaactgg
    43021 cgtaagataa ttgattattt cagttctgcg acacagattg ggatgaccgc tactcctaaa
    43081 gaaaccaaga atgcttccaa tacggaatac tttggtgagc caatctatac ttatagttta
    43141 aaacagggaa tcgaggatgg ttttttggct ccatatcgtg ttatgagagt taatttagat
    43201 gtagatgtgg atggttatcg tccagaaact ggaaaagttg atgctaacgg acaattaata
    43261 gaagataggt actacggcag gaaagatttt gataaaacca ttgtcattga tgatagaacg
    43321 caaagagttg ccaagtttgt ttctgattat atgaagcaaa acaatgcacg atttgataaa
    43381 acaattgttt tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc acttgtaaaa
    43441 gagaatctag acttagtcca agaagactat cgttatgtca tgcaagtaac tggtgacaac
    43501 gctgaaggaa aagctcaact ggataacttt atggatgtca attctaattt tcccgctatt
    43561 gtaacaacgt ctaaattatt aacgacagga gttaatgcta aaacatgtcg tttgattgtt
    43621 ttagactcta atatccaatc catgactgaa tttaaacaaa ttattggtcg tggcacacgt
    43681 ctttatcctc aaaaggggaa agaatttttt acgattattg attttcgaaa tgttaccaat
    43741 ttgtttgctg accctgattt tgatggtgat ccagtgaagg tgctggaaac aggtgcgaaa
    43801 acagtcagtg gttctacgcc cggtttcgta agtgaggaag gtgacccagt agaaaaatat
    43861 atcgttacag acaagcaggt taccattctt aattctactg ttcaagtatt ggatgaaaac
    43921 gggaaactga ttaccgaaag cctgaccgac tacactcgga agaatatctt aggtagctac
    43981 gccactttga acgattttat cacagtttgg catacggcgg ataaaaagaa gcttatctta
    44041 gacgaacttt ataaaaaagg agtttatcta gatgctattc gagagtcgga gggaatatca
    44101 gaacaagaaa tcgatgattt tgatttactc ctaaaacttg cctatggtca aaaagaatta
    44161 accaaaacgg aacgtatcaa taagctcaaa caaagcggat atttatataa atatagtgag
    44221 gaagcgcgtg ctgttttgga aattttactg aacaaataca tggataaagg tattggagaa
    44281 ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga tatatggtgg aaccttcaaa
    44341 atcatcaata cttattttgg agataaaaaa cgatatttac aagcaattaa agaattggag
    44401 caagagctat ttacagtagc ttaatgaaag gaaagtatgt caattacatc atttgtaaaa
    44461 agaattcaag atatcactcg aaacgatgct ggtgttaatg gtgatgctca acgtattgag
    44521 caaatgtctt ggttattatt cttaaaaatt tatgatagcc gtgaaatggt ttgggaatta
    44581 gaagaagacg agtatgagtc aattatccca gaggaattaa aatggcgaaa ttgggctcat
    44641 gctcaaaatg gggaacgggt attgacaggc gatgaattac ttgattttgt caataacaag
    44701 ttattcaaag agttgaaaga gcttgaaata acttcaaata tgcctattcg aaaaacgatt
    44761 gttaaatcag cttttaaaga tgcgaacaac tatatgaaaa atggcgtctt gttacgccaa
    44821 gtcatcaatg ttattgatga agttgatttc aatagccctg aagatcgtca ttcgtttaat
    44881 gatatttacg aaaaaattct taaagatatt caaaatgctg ggaactcagg agaattttat
    44941 acaccacgtg cagcgactga ttttattgcc gaagttcttg acccaaaact tggagaatca
    45001 atggcagacc ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa ccgtttaagt
    45061 agtcaacgta aaactagtga agataccaaa aaatataata cagctgtttt tggtattgaa
    45121 aagaaagcat ttcctcatct tttagcagtt acaaatctgt ttcttcacga aattgatgac
    45181 cctaaaattg ttcatggaaa tactttagag aaaaatgttc gtgaatatac ggatgatgaa
    45241 aaatttgaca ttattatgat gaatccacct tttggagggt cagaattaga aacaataaaa
    45301 aataactttc cagcagaatt acggagttct gaaacagctg atttatttat ggctgtcatt
    45361 atgtatcgtt tgaaagaaaa tggtcgtgtt ggagttattt tacctgatgg ttttctattt
    45421 ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag atgagttcaa cttgcatacg
    45481 attattaggt tgcctcatag tgtctttgca ccgtatacag gaatccatac gaacattctt
    45541 ttctttgata aaacaaagaa aacagaagaa acttggtttt atcgtttaga tatgccagat
    45601 ggttataaaa atttctcgaa aactaagccg atgaagtcag aacacttcaa tcctgttcgt
    45661 gactggtggg aaaatcgtga agagattctg gaaggtaagt tctacaaatc taaatcattt
    45721 acacctagtg aattggctga gttgaattat aatttagacc agtgtggttt tccaaaagag
    45781 gaagaggaaa tcttaaatcc ctttgagttg attcagaatt atcaagcgga aagagcaact
    45841 ttaaatcata agattgataa tgtattagct gatattttgc agttgttgga ggacaaataa
    45901 tgacaccaga acaacttaag gcaagtattc tccaaagagc gatggaaggg aaattagtgc
    45961 cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa gagaattaaa gctgaaaaag
    46021 aaaaacttat cagtgaagga aaaatcaaac gagataaaaa ggaaactgag atatttcgtg
    46081 gtgatgatgg gaaacattat gggaagtttg ctgatggaag tactcaagaa attgatgttc
    46141 cttatgatat tcctgatact tgggagtggg tgaggataaa atcaatttat tggaattttg
    46201 ggcaaaataa gccagagaaa tcctttaggt atatagatac gtctagtatt gatagaaaaa
    46261 agaacataat caactacaaa aatctacaat atctttcacc tgaacaagcg ccttcccgtg
    46321 ctagaaaatt agtttcgcag aatagtgtct tattttcaac agttagacca tatctaaaaa
    46381 atattgctgt agttagagaa cttaaagagt atttgatagc tagtacagca tttattgttt
    46441 tggatacttt acttaacgaa acatatttga aatattattt attatcagat aatt
//
LOCUS       DAVLBN010000009        44715 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLBN010000009 DAVLBN010000000
VERSION     DAVLBN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.009"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VXC24_000490"
     CDS             complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VXC24_000490"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0492656.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VXC24_000491"
     CDS             complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VXC24_000491"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0492657.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7816..7886
                     /locus_tag="VXC24_000492"
     tRNA            7816..7886
                     /locus_tag="VXC24_000492"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7848..7850,aa:Cys,seq:gca)
     gene            complement(8084..9415)
                     /locus_tag="VXC24_000493"
     CDS             complement(8084..9415)
                     /locus_tag="VXC24_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0492658.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VXC24_000494"
     CDS             complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VXC24_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0492659.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10507..10695)
                     /locus_tag="VXC24_000495"
     CDS             complement(10507..10695)
                     /locus_tag="VXC24_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0492660.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VXC24_000496"
     CDS             complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VXC24_000496"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0492661.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11995..12225)
                     /locus_tag="VXC24_000497"
     CDS             complement(11995..12225)
                     /locus_tag="VXC24_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0492662.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12283..13320)
                     /locus_tag="VXC24_000498"
     CDS             complement(12283..13320)
                     /locus_tag="VXC24_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0492663.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VXC24_000499"
     CDS             complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VXC24_000499"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0492664.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VXC24_000500"
     CDS             complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VXC24_000500"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0492665.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14386..15378)
                     /locus_tag="VXC24_000501"
     CDS             complement(14386..15378)
                     /locus_tag="VXC24_000501"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0492666.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15490..16173)
                     /locus_tag="VXC24_000502"
     CDS             complement(15490..16173)
                     /locus_tag="VXC24_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0492667.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16229..16969)
                     /locus_tag="VXC24_000503"
     CDS             complement(16229..16969)
                     /locus_tag="VXC24_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0492668.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17003..17281
                     /locus_tag="VXC24_000504"
     CDS             17003..17281
                     /locus_tag="VXC24_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0492669.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17359..18285
                     /gene="yidC"
                     /locus_tag="VXC24_000505"
     CDS             17359..18285
                     /gene="yidC"
                     /locus_tag="VXC24_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0492670.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VXC24_000506"
     CDS             complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VXC24_000506"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0492671.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19280..20530)
                     /locus_tag="VXC24_000507"
     CDS             complement(19280..20530)
                     /locus_tag="VXC24_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0492672.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VXC24_000508"
     CDS             complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VXC24_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0492673.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21691..22632)
                     /locus_tag="VXC24_000509"
     CDS             complement(21691..22632)
                     /locus_tag="VXC24_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0492674.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22622..23878)
                     /locus_tag="VXC24_000510"
     CDS             complement(22622..23878)
                     /locus_tag="VXC24_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0492675.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23880..24542)
                     /locus_tag="VXC24_000511"
     CDS             complement(23880..24542)
                     /locus_tag="VXC24_000511"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0492676.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24505..25161)
                     /locus_tag="VXC24_000512"
     CDS             complement(24505..25161)
                     /locus_tag="VXC24_000512"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0492677.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VXC24_000513"
     CDS             complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VXC24_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0492678.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VXC24_000514"
     CDS             complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VXC24_000514"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0492679.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27055..27363)
                     /locus_tag="VXC24_000515"
     CDS             complement(27055..27363)
                     /locus_tag="VXC24_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492680.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27356..27997)
                     /locus_tag="VXC24_000516"
     CDS             complement(27356..27997)
                     /locus_tag="VXC24_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492681.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27999..30029)
                     /locus_tag="VXC24_000517"
     CDS             complement(27999..30029)
                     /locus_tag="VXC24_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0492682.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30298..31197)
                     /locus_tag="VXC24_000518"
     CDS             complement(30298..31197)
                     /locus_tag="VXC24_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0492683.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VXC24_000519"
     CDS             complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VXC24_000519"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0492684.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31829..32602)
                     /locus_tag="VXC24_000520"
     CDS             complement(31829..32602)
                     /locus_tag="VXC24_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0492685.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32907..33800)
                     /locus_tag="VXC24_000521"
     CDS             complement(32907..33800)
                     /locus_tag="VXC24_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0492686.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VXC24_000522"
     CDS             complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VXC24_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0492687.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34363..35577)
                     /locus_tag="VXC24_000523"
     CDS             complement(34363..35577)
                     /locus_tag="VXC24_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0492688.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35733..36027)
                     /locus_tag="VXC24_000524"
                     /pseudo
     CDS             complement(35733..36027)
                     /locus_tag="VXC24_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36189..36641
                     /locus_tag="VXC24_000525"
     CDS             36189..36641
                     /locus_tag="VXC24_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0492689.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36676..38064)
                     /locus_tag="VXC24_000526"
     CDS             complement(36676..38064)
                     /locus_tag="VXC24_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0492690.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38130..39092
                     /locus_tag="VXC24_000527"
     CDS             38130..39092
                     /locus_tag="VXC24_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0492691.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39121..39279)
                     /locus_tag="VXC24_000528"
     CDS             complement(39121..39279)
                     /locus_tag="VXC24_000528"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492692.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VXC24_000529"
     CDS             complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VXC24_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0492693.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40778..41377)
                     /locus_tag="VXC24_000530"
     CDS             complement(40778..41377)
                     /locus_tag="VXC24_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492694.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41379..42476)
                     /locus_tag="VXC24_000531"
     CDS             complement(41379..42476)
                     /locus_tag="VXC24_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0492695.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42476..43213)
                     /locus_tag="VXC24_000532"
     CDS             complement(42476..43213)
                     /locus_tag="VXC24_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492696.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43215..44099)
                     /locus_tag="VXC24_000533"
     CDS             complement(43215..44099)
                     /locus_tag="VXC24_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492697.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44086..44280)
                     /locus_tag="VXC24_000534"
     CDS             complement(44086..44280)
                     /locus_tag="VXC24_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492698.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44277..44483)
                     /locus_tag="VXC24_000535"
     CDS             complement(44277..44483)
                     /locus_tag="VXC24_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492699.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12742 a        10445 c         8514 g        13014 t
ORIGIN      
        1 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
       61 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
      121 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
      181 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
      241 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
      301 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
      361 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
      421 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
      481 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
      541 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
      601 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
      661 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
      721 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
      781 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
      841 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
      901 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
      961 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     1021 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     1081 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     1141 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     1201 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     1261 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     1321 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     1381 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     1441 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     1501 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     1561 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     1621 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     1681 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     1741 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     1801 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     1861 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     1921 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     1981 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     2041 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     2101 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     2161 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     2221 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     2281 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     2341 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     2401 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     2461 aattaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     2521 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     2581 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     2641 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     2701 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     2761 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     2821 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcatcaac
     2881 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     2941 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     3001 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     3061 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     3121 atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt
     3181 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     3241 acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg
     3301 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     3361 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     3421 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     3481 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     3541 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     3601 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     3661 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     3721 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     3781 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     3841 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     3901 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     3961 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     4021 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     4081 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     4141 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     4201 ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa
     4261 cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat gactccaaca
     4321 gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg
     4381 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     4441 actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     4501 acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga
     4561 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     4621 tttccatgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
     4681 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
     4741 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
     4801 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
     4861 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
     4921 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
     4981 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
     5041 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
     5101 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
     5161 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
     5221 tttacgagag tgcgttggtt gtaagcagta cctgagtttg aacgacggaa tttttggatg
     5281 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
     5341 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
     5401 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
     5461 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
     5581 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
     5641 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
     5701 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
     5761 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
     5821 ggtccttcag gtgtttcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
     5881 acttcatatc cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
     5941 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
     6001 ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg ttgtggtgtc
     6061 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
     6121 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
     6181 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
     6241 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
     6301 atcgttacga cgcgatctgg atcagttgga gcaacaacct tgaatttttg aagaacaaca
     6361 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
     6421 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
     6481 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt
     6541 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc atagcgacgt
     6601 gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagctgtctt aggctcacct
     6661 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
     6721 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
     6781 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
     6841 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
     6901 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
     6961 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
     7021 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
     7081 ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
     7141 ctagcatcgt ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca
     7201 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
     7261 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
     7321 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
     7381 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
     7441 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
     7501 tttcagaatc tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag
     7561 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
     7621 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
     7681 aaggggtttc agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
     7741 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
     7801 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
     7861 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
     7921 gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa taaatacgta taactttaaa
     7981 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
     8041 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
     8101 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
     8161 cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg
     8221 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
     8281 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
     8341 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
     8401 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
     8461 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
     8521 caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt
     8581 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
     8641 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
     8701 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggcaccataa
     8761 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
     8821 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
     8881 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
     8941 aaagccaaac aaaaggactg actagttttc cgatcccaat gataatcggc gctgtacgaa
     9001 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
     9061 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
     9121 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
     9181 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
     9241 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
     9301 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
     9361 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
     9421 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
     9481 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
     9541 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
     9601 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
     9661 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
     9721 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
     9781 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
     9841 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
     9901 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
     9961 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    10021 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    10081 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    10141 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    10201 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    10261 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    10321 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    10381 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    10441 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    10501 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    10561 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    10621 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    10681 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    10741 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    10801 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    10861 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    10921 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    10981 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    11041 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    11101 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    11161 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    11221 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    11281 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    11341 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    11401 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    11461 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    11521 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    11581 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    11641 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    11701 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    11761 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    11821 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    11881 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    11941 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    12001 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    12061 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattatcatc
    12121 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    12181 aataaagaac atatgactac ttagagtgaa taataattga accatttgac tattatacca
    12241 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    12301 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    12361 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    12421 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    12481 tacaaccttc ttatcaatgc ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    12541 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    12601 tagactaaac atgagaccag cacttgggcc gccaatacca gctgttgaaa agctaattgg
    12661 gacattgctg attacctctg tacgatcaat caagccgatt ccaattccat ttttgccatt
    12721 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    12781 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    12841 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    12901 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    12961 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    13021 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    13081 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    13141 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg
    13201 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    13261 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    13321 ttcttatttc ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca
    13381 aaagctctcg aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa
    13441 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca
    13501 aatccgccgc attcctcaac ccccgtacta ggaaagtagc ccccagtctt tttgcaacat
    13561 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    13621 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    13681 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    13741 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    13801 accttactaa ttccataaat cttttccttc cagataccca gacaggcaat ctcttctgga
    13861 agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    13921 ttagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    13981 acgaggtcaa attccccaga tacctgttcc aatgccctct ctgcatccat cttgaggagt
    14041 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    14101 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    14161 ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg accaatcatg
    14221 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc ttctagtgtc
    14281 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    14341 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    14401 gtaagtatcg cgtacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    14461 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    14521 taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    14581 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    14641 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    14701 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    14761 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    14821 ttcacgttct ttcgatgtca agtctggata gcgttctacc aattcttctg tatggataaa
    14881 ggtgatttgt tttggcaaga tagactcgat gtcatagcga gcttcaacag ctagctcagt
    14941 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    15001 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    15061 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    15121 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    15181 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    15241 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    15301 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    15361 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    15421 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    15481 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    15541 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    15601 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    15661 aaccatggct acactaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    15721 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    15781 tttcttggta aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    15841 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    15901 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    15961 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    16021 ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    16081 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    16141 acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt
    16201 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    16261 caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    16321 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    16381 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    16441 ctgggatagc taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg
    16501 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    16561 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    16621 ctacattacc gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    16681 cttgtcctac ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg
    16741 ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat
    16801 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    16861 caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt
    16921 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    16981 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    17041 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    17101 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    17161 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    17221 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    17281 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    17341 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    17401 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    17461 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    17521 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    17581 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    17641 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    17701 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    17761 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    17821 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    17881 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    17941 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    18001 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    18061 gttgtcggtg gtttcatgat gattctccag caatttatcg tcaactatat cgttcgtcca
    18121 aaacttcgca aaaaagtcca tgaagaactg gcaaagaacc catcaaaagc aagtgctttc
    18181 tcaacaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag
    18241 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    18301 gctgatttgc taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc
    18361 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    18421 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    18481 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    18541 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    18601 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    18661 gccaagatat ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc
    18721 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    18781 cgcggtttat tacggaaagg aagagcacag gtgtccaagg tacagtggat tccttgttcc
    18841 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    18901 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    18961 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    19021 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    19081 tctactgacc caaagctttc tgtcgaatgc accatccctg tcacttgtcc ataatcaatt
    19141 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    19201 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    19261 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    19321 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    19381 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    19441 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    19501 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    19561 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    19621 ctgaggcatc tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga
    19681 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    19741 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    19801 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    19861 taaagtctaa cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    19921 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc
    19981 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    20041 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    20101 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    20161 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    20221 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    20281 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    20341 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    20401 tccacgaaaa agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca
    20461 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    20521 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    20581 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    20641 cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt
    20701 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    20761 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    20821 tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    20881 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    20941 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    21001 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    21061 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    21121 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    21181 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    21241 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    21301 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    21361 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    21421 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    21481 tcgctggtgg ttcaaaacac tgctttgaga ttgtcgatag aactgacaaa ccctgtaata
    21541 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    21601 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    21661 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    21721 attatccata gcgaagattt tattggacat ctctccttta tccaccaaag ccagagctgt
    21781 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat
    21841 aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg
    21901 acgaagcaaa acgacttctt ccttggtatc gtcgatgccg agttccataa ctgtcttggt
    21961 aatttcgcta tcaatgagag cgatatgtcc aagaagattg cctcgcactg tgtactctgt
    22021 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    22081 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    22141 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    22201 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    22261 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    22321 tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag
    22381 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    22441 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    22501 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    22561 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg
    22621 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac
    22681 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    22741 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    22801 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    22861 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    22921 ttggtcctgc aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    22981 ggacgatttc tgagtagaga ccttctgtcg gaacaaacaa gattccaaaa ttggttgtcc
    23041 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    23101 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    23161 ggtaataatc tgccagtgga aacttagagt caattggaag atagacgtat tcttggtcgc
    23221 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    23281 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    23341 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    23401 gggcaactgt ctgcatttct ccaagaccac gattgacaga ctccagttgt ttagaaactg
    23461 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    23521 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    23581 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcaggcctt
    23641 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc aaatcttttt
    23701 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    23761 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    23821 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    23881 tacctcctat ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    23941 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    24001 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    24061 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    24121 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    24181 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    24241 tgagcctgag gattttgttc aaagatggtt aagagagcca attccaaatc ggtatcatct
    24301 ttttctggtc gtgcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    24361 tcggtcacag aatcaaaatc cccaactgct agagcaagag gcaagtcttc ttccaagacc
    24421 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    24481 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    24541 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    24601 agcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    24661 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    24721 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    24781 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    24841 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    24901 gatgtctgca cctgcgcgcg caaagtcttc cagatggtgt tcaggattcg ccaccatcaa
    24961 gtgacagtca aagaccatct tactatgtgg acgaagtgct tcaaccacac cggcaccaaa
    25021 actgatttgt ggcacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    25081 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    25141 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    25201 tatgggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    25261 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    25321 gggtacaagt acgaaactta caatctcggc tgacagtagc aatctctggg aaagcctgat
    25381 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtgtctgcga
    25441 ttttaccccc attgaggttg aaaaaactaa cagctcgagt agtatggcgc ccacgaccca
    25501 gactgtctga gatttctcct gtttcaagat tgaggtctgg tgcgattttg ttgagaagag
    25561 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    25621 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    25681 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    25741 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    25801 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    25861 tgtttttccg ttcgtgaatt tttaggatat agccttctga attttcctcg gcagagaaat
    25921 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    25981 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    26041 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagacaggc aaattctgcc
    26101 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    26161 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    26221 ttacggcgat gggtaaaact agccttggaa accttaaaga agaagttctc atcttccact
    26281 gctacagctg gctctggacg gcgcaccatt ttcaagatgg ctgaatccac atttggcgct
    26341 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    26401 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    26461 tctttctgca tcatgaccac aaactcacta aaaggaatcc cactctcaat caagtgcatg
    26521 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    26581 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactaca
    26641 gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc
    26701 tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc accaatacct
    26761 ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac aattttttga
    26821 aggatattgg tatccgtcag gaaattttgc ccgaaggact ttttaaaggt aaaaccgtga
    26881 cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    26941 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    27001 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttaaca
    27061 gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcgggtag
    27121 ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt
    27181 tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc
    27241 atgtactcgg atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc
    27301 ttctaaacca cctctggcac taggataatc agatactctg cgaatacgga ttttttcaca
    27361 catgagcaag tttcctcata tcaatgattt catcagcctt attccagact aggggattat
    27421 gggtcgcaat gatgatcatt cgattttcat ctttcaaatc caccaagaga ttcataacct
    27481 cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat
    27541 ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataaa
    27601 ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc acttgccttt
    27661 ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga
    27721 ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga tctcgaaaat
    27781 actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt cctccatcta
    27841 tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga
    27901 ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt
    27961 cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc
    28021 atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta
    28081 aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact
    28141 aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt
    28201 gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa atagagaaga
    28261 ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga
    28321 gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc
    28381 aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct gtctccatat
    28441 cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt
    28501 gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt
    28561 gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt
    28621 acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc
    28681 aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct ctcaggcaag
    28741 atcagcccaa actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg
    28801 gtaatctttt cttctatcag atagcgtggt gagacataga taacattccc tgacggtgtg
    28861 tagtcactga gacgattacc atctaggtcc acttctgctc catctgagaa attgtcaaca
    28921 ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac
    28981 tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat
    29041 agacggtaac ggtctgagta ctggctccat ttattgctag ctctctccat ttcctgcatt
    29101 tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt
    29161 tgccccacca tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc
    29221 accagactat tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct
    29281 gccaagatca atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac
    29341 aaggcacctt gataccagag aatccccaat cccaaaatac tggataccag cactgagcag
    29401 ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca
    29461 gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc
    29521 ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt
    29581 aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc aagttctttc
    29641 aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta agaccctaat
    29701 aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg aagctctccc
    29761 tcaccataag tggcataggt aaagagtgtt tctccagctt catttggctc aacgattcga
    29821 cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt caccttttcg
    29881 cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca
    29941 aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga taccaatacc
    30001 attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact tggtcactta
    30061 gtgagaaggt gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc
    30121 aacatcttca aatatattat atccgttttt tcaagaacta tcaaggacat caatgtcctt
    30181 aaaatctaac tatttcatat tatttttagc ttatatctaa aaaaacagtt ctaaagacga
    30241 actttagaac tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta
    30301 taaatatttt ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaatccatc
    30361 tccaattagc ttcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc
    30421 tctttctact cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata
    30481 atcttgagtt ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt
    30541 tactcctacc ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta
    30601 attctctatt tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg
    30661 atttataaat ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa
    30721 caacatatca tttgttgaat aaacttcttt ttctatgatc tgagacatat gttcctcaag
    30781 tattaactct gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac
    30841 ttcacatgct aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc
    30901 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    30961 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    31021 aactggaact cctagccggc gagcaatata gtctaacttg ggcaaactcg gttgcgaagc
    31081 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    31141 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    31201 acgcctcctc ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca
    31261 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    31321 aactctaggc gtttgaggag ttgcttgccg ttagaatagc cgattcggag agtctctccg
    31381 agatattctc tacgcttaca gctgtctgcc cctgctagaa aaccaaggcg aatcaagtcg
    31441 ctacgactaa tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc
    31501 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    31561 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg
    31621 atcatgcgcc gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga
    31681 cgttggtgca ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc
    31741 tcataggtct ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc
    31801 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    31861 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    31921 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    31981 ctaagtaagg cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt
    32041 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    32101 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    32161 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    32221 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    32281 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    32341 caaccttgga atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    32401 cagcttctgt aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact
    32461 ccaaggcatg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    32521 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    32581 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    32641 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    32701 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    32761 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    32821 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    32881 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    32941 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    33001 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    33061 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    33121 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    33181 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    33241 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    33301 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    33361 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    33421 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    33481 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    33541 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    33601 gctgtaccat ctccagctac attgattgtc gctccgtcta atgctgaacc atttgcttgt
    33661 aaaatagcaa ccttaacttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    33721 ctttgagcag gtgctttaac agttgatttt tcagcagtca gtttagtgct atcttgtgct
    33781 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    33841 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    33901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    33961 ctattctagt ttcaatctac tgtaacatcg cttccgaatc cgtttgcatc tactgaactt
    34021 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    34081 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    34141 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    34201 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    34261 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    34321 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    34381 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    34441 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    34501 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    34561 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    34621 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    34681 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    34741 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    34801 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    34861 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    34921 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    34981 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    35041 gttattggga ttgataagga caattgcctt ggtattggaa gtgatttttg acttgatatc
    35101 gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg catttcctcc
    35161 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    35221 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    35281 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    35341 cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac gcgcattcat
    35401 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    35461 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    35521 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    35581 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    35641 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    35701 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    35761 aagcaagcct agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat
    35821 caagtaatcc caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac
    35881 atgaaaaact aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg
    35941 acagatcatg atcacttcta ccaagactga aactaggata attccataat aaaggaaatt
    36001 tgatttttga aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt
    36061 tcttttattt tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac
    36121 tttttttgct ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag
    36181 gtttcattat ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag
    36241 cggacttggc ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca
    36301 tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt
    36361 acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag
    36421 atgctggggt agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag
    36481 cacgtactat tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca
    36541 acgcctttga acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg
    36601 tcgatttgct ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc
    36661 ctagctcctt tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg
    36721 gcgctgcagt tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg
    36781 ttttaagatt ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc
    36841 catattggcc tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa
    36901 actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg
    36961 ctgagcaggt gtcttcttgg ctactttacc tgctgcctta tcaagggcct gatgaagttg
    37021 cgatacagct tgaccaaaat cttcttcaga aggactggct gatcgaacaa actccaccaa
    37081 ttcttctatt ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc
    37141 ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc
    37201 acggctgaca aaaacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat
    37261 cccatcttgt tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc
    37321 atttcccata gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc
    37381 accaaaagcc atgacttggt tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc
    37441 ttctaattta gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa
    37501 tttcaagtct tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa
    37561 aacttggtaa ataggttgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac
    37621 cttgctgacc atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa
    37681 gcgactaatt cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat
    37741 ggcatccttg gtccctaagg caatctccgt gccctctttt ttagcatagc taattagatg
    37801 gcgcaaatgt aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata
    37861 ctggccatta taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa
    37921 aaaaggtcct cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat
    37981 cgcgtcctta gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc
    38041 aaaaaaaaca gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta
    38101 taccacattt cagaaagagt gagtaaatca tgcctaagaa aatccttgtt ttacatacgg
    38161 gtggaactat ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc
    38221 ccatgaacca tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta
    38281 accttccaag tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag
    38341 aggaagcaga taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa
    38401 cagcctattt ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca
    38461 tgcgtagctc caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag
    38521 tggccagcga tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc
    38581 acgctgccaa gtatgtcacc aaaacacata cgactaatgt cagcaccttc cagactccaa
    38641 cacatggccc cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac
    38701 ctcgtgttcg ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg
    38761 ctggtatgac agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta
    38821 tccaagcctt cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc
    38881 tgcaaaaagg aattccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg
    38941 tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag
    39001 aactcaacgc ccaaaaagct cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag
    39061 gacaggcttt gaaaaactat atggaaggct aatactcttc gaaaatctct gcaaaccacg
    39121 tcacgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    39181 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca
    39241 gcctttaacc agtcgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta
    39301 agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt
    39361 tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt
    39421 atgcataatc ttggtcaaca tacgcatact aatggcacca agatcataaa gaggttgggc
    39481 aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat
    39541 ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc
    39601 caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa
    39661 ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat
    39721 tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc
    39781 cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt aactcactgc
    39841 atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac
    39901 agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt
    39961 caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac
    40021 agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat
    40081 ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg
    40141 aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg
    40201 acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt
    40261 tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac
    40321 atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca
    40381 cattctttta caagtagagg tactgattga agctctatat ctacttacaa aagtgaagat
    40441 gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg taaacacttt
    40501 caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg
    40561 ctaccacctt agactaaaca caaaggagga aactaagccc tcctaaagtt atagtaaaat
    40621 gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    40681 agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc
    40741 aattttagca catagccttc ataaaaatat tatatcatca taaccaacca gattcttttg
    40801 cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata ttggtgacat
    40861 agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg ttggataagc
    40921 cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg ggacgggtca
    40981 tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg
    41041 tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact ccagccttga
    41101 ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa
    41161 gcctttctga tcgtatccac tccaagactt caagacctgt cttaacaggc atttctacgt
    41221 caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct tgcccattct
    41281 tggcttgaag gacagactcc acatctggtt gaagcgtgag caattgacac atggcatctc
    41341 gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc cttataaggt
    41401 agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat
    41461 ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc aaagccgcag
    41521 ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt taagtaagct
    41581 ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat catagaagtc
    41641 attgcctcca attcttgagt aaggctagca gtatctagtt ggttatccgt ttccacctca
    41701 attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac
    41761 ttaagatttt ccacaatggt tcgaacttca cgcatcgatt ctttgctaat ttgctgtatt
    41821 tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg caaggctaga
    41881 tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa atcctgaccg
    41941 atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg ctcgacctga
    42001 gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca
    42061 aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg aaaaatcaaa
    42121 agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa agactttaaa
    42181 ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa ccagatataa
    42241 ttcccagcaa caaaggcggt attcccagct acatagacca gcatgatccc ccagaaaagc
    42301 caagataggc gctggttctt agttattaaa acacccaaat acgtcactac aaatagaata
    42361 tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat gggaaaaagc
    42421 ataaaaatca aactgaccca aaacatatag tgtatgcttt tcagtctttc aagcattaag
    42481 cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa
    42541 gtaaataaac tgtggctgat agattgatgc caccctcgtt taagaaggtc ttgagcaact
    42601 ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct ggaaataaag
    42661 aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga ttgcccacaa
    42721 cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct acaaaagcaa
    42781 tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc atgtctacac
    42841 ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa tcaaccagca
    42901 tacttgttat ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt
    42961 tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg atagttgtcg
    43021 acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc gcgggttcac
    43081 ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc atccctaccg
    43141 acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta
    43201 tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt attcaacaaa
    43261 ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa tagttcccag
    43321 aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt ccagttttca
    43381 accaaatttg actgctctac gacttccttg taagctatag gaaggataaa gtgcttttct
    43441 atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc cttatttaag
    43501 agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga atagagaatg
    43561 gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg agttgaggta
    43621 tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat taaggtcaag
    43681 atgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg ttctttttgt
    43741 tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt tggatagata
    43801 cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac attttcttga
    43861 gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc ttgaatagat
    43921 acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt tgtctttccg
    43981 gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc
    44041 cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac caccgtcatg
    44101 agactctcct ttcaaccact ccattcccat agggaaaacg acgaaaatca taaatccaaa
    44161 ccccaaagca ccatgaatga attggcgaag caaggcttga tcaaaccaat cagtaaacat
    44221 ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc ctctcttcat
    44281 tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac aagccaagac
    44341 atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc atccaatccc
    44401 gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat aatcatttta
    44461 tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa atcagaggag
    44521 gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa
    44581 gcaagataca ctatacaata aaacacaatc agaaaaatct aaggcaactt cctcaaaaga
    44641 gatatcaaac tcaattcaca ccataatgta aactaatact tatttaaaat caaaaagagt
    44701 agaaattttt atcag
//
LOCUS       DAVLBN010000010        43834 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLBN010000010 DAVLBN010000000
VERSION     DAVLBN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.010"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(115..1749)
                     /locus_tag="VXC24_000536"
     CDS             complement(115..1749)
                     /locus_tag="VXC24_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492700.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1730..2479)
                     /locus_tag="VXC24_000537"
     CDS             complement(1730..2479)
                     /locus_tag="VXC24_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492701.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            2658..4112
                     /locus_tag="VXC24_000538"
     CDS             2658..4112
                     /locus_tag="VXC24_000538"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0492702.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4202..6820)
                     /gene="alaS"
                     /locus_tag="VXC24_000539"
     CDS             complement(4202..6820)
                     /gene="alaS"
                     /locus_tag="VXC24_000539"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0492703.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(6842..7327)
                     /locus_tag="VXC24_000540"
     CDS             complement(6842..7327)
                     /locus_tag="VXC24_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0492704.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7602..7841)
                     /locus_tag="VXC24_000541"
     CDS             complement(7602..7841)
                     /locus_tag="VXC24_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492705.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8110..9180)
                     /locus_tag="VXC24_000542"
     CDS             complement(8110..9180)
                     /locus_tag="VXC24_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0492706.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9177..9950)
                     /locus_tag="VXC24_000543"
     CDS             complement(9177..9950)
                     /locus_tag="VXC24_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492707.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9947..10753)
                     /locus_tag="VXC24_000544"
     CDS             complement(9947..10753)
                     /locus_tag="VXC24_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492708.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10734..11891)
                     /locus_tag="VXC24_000545"
     CDS             complement(10734..11891)
                     /locus_tag="VXC24_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492709.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12052..12957)
                     /gene="murB"
                     /locus_tag="VXC24_000546"
     CDS             complement(12052..12957)
                     /gene="murB"
                     /locus_tag="VXC24_000546"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0492710.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13069..13821)
                     /locus_tag="VXC24_000547"
                     /pseudo
     CDS             complement(13069..13821)
                     /locus_tag="VXC24_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13831..14562)
                     /gene="budA"
                     /locus_tag="VXC24_000548"
     CDS             complement(13831..14562)
                     /gene="budA"
                     /locus_tag="VXC24_000548"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0492711.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(15046..15567)
                     /locus_tag="VXC24_000549"
     CDS             complement(15046..15567)
                     /locus_tag="VXC24_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HEV0492712.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            15998..17269
                     /locus_tag="VXC24_000550"
     CDS             15998..17269
                     /locus_tag="VXC24_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0492713.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(17289..18104)
                     /locus_tag="VXC24_000551"
     CDS             complement(17289..18104)
                     /locus_tag="VXC24_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0492714.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(18261..18914)
                     /gene="phoU"
                     /locus_tag="VXC24_000552"
     CDS             complement(18261..18914)
                     /gene="phoU"
                     /locus_tag="VXC24_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0492715.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(18926..19684)
                     /gene="pstB"
                     /locus_tag="VXC24_000553"
     CDS             complement(18926..19684)
                     /gene="pstB"
                     /locus_tag="VXC24_000553"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0492716.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(19697..20500)
                     /gene="pstB"
                     /locus_tag="VXC24_000554"
     CDS             complement(19697..20500)
                     /gene="pstB"
                     /locus_tag="VXC24_000554"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0492717.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(20511..21395)
                     /gene="pstA"
                     /locus_tag="VXC24_000555"
     CDS             complement(20511..21395)
                     /gene="pstA"
                     /locus_tag="VXC24_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0492718.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(21385..22302)
                     /gene="pstC"
                     /locus_tag="VXC24_000556"
     CDS             complement(21385..22302)
                     /gene="pstC"
                     /locus_tag="VXC24_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0492719.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(22302..23180)
                     /gene="pstS"
                     /locus_tag="VXC24_000557"
     CDS             complement(22302..23180)
                     /gene="pstS"
                     /locus_tag="VXC24_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0492720.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(23754..25058)
                     /locus_tag="VXC24_000558"
     CDS             complement(23754..25058)
                     /locus_tag="VXC24_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0492721.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(25059..25832)
                     /locus_tag="VXC24_000559"
     CDS             complement(25059..25832)
                     /locus_tag="VXC24_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0492722.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(25822..26100)
                     /locus_tag="VXC24_000560"
     CDS             complement(25822..26100)
                     /locus_tag="VXC24_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0492723.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(26100..26501)
                     /locus_tag="VXC24_000561"
     CDS             complement(26100..26501)
                     /locus_tag="VXC24_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0492724.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(26711..27328)
                     /locus_tag="VXC24_000562"
     CDS             complement(26711..27328)
                     /locus_tag="VXC24_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0492725.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(27318..28091)
                     /locus_tag="VXC24_000563"
     CDS             complement(27318..28091)
                     /locus_tag="VXC24_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0492726.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(28102..28839)
                     /locus_tag="VXC24_000564"
     CDS             complement(28102..28839)
                     /locus_tag="VXC24_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0492727.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(28844..29974)
                     /locus_tag="VXC24_000565"
     CDS             complement(28844..29974)
                     /locus_tag="VXC24_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0492728.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(30058..30447)
                     /locus_tag="VXC24_000566"
     CDS             complement(30058..30447)
                     /locus_tag="VXC24_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0492729.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(30463..30846)
                     /locus_tag="VXC24_000567"
     CDS             complement(30463..30846)
                     /locus_tag="VXC24_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0492730.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(30847..31635)
                     /locus_tag="VXC24_000568"
     CDS             complement(30847..31635)
                     /locus_tag="VXC24_000568"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0492731.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(31628..32563)
                     /locus_tag="VXC24_000569"
     CDS             complement(31628..32563)
                     /locus_tag="VXC24_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0492732.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(32693..32869)
                     /locus_tag="VXC24_000570"
     CDS             complement(32693..32869)
                     /locus_tag="VXC24_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0492733.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(33009..33716)
                     /locus_tag="VXC24_000571"
     CDS             complement(33009..33716)
                     /locus_tag="VXC24_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0492734.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            33867..34895
                     /gene="queA"
                     /locus_tag="VXC24_000572"
     CDS             33867..34895
                     /gene="queA"
                     /locus_tag="VXC24_000572"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0492735.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(35556..35945)
                     /locus_tag="VXC24_000573"
     CDS             complement(35556..35945)
                     /locus_tag="VXC24_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0492736.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(36049..36690)
                     /locus_tag="VXC24_000574"
     CDS             complement(36049..36690)
                     /locus_tag="VXC24_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002871528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0492737.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK"
     gene            complement(37404..37955)
                     /locus_tag="VXC24_000575"
     CDS             complement(37404..37955)
                     /locus_tag="VXC24_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0492738.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(38354..39178)
                     /gene="nadE"
                     /locus_tag="VXC24_000576"
     CDS             complement(38354..39178)
                     /gene="nadE"
                     /locus_tag="VXC24_000576"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0492739.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(39175..40635)
                     /locus_tag="VXC24_000577"
     CDS             complement(39175..40635)
                     /locus_tag="VXC24_000577"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0492740.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(40751..41239)
                     /locus_tag="VXC24_000578"
     CDS             complement(40751..41239)
                     /locus_tag="VXC24_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492741.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(41229..41438)
                     /locus_tag="VXC24_000579"
     CDS             complement(41229..41438)
                     /locus_tag="VXC24_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0492742.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(41823..42551)
                     /locus_tag="VXC24_000580"
     CDS             complement(41823..42551)
                     /locus_tag="VXC24_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492743.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(42567..43358)
                     /locus_tag="VXC24_000581"
     CDS             complement(42567..43358)
                     /locus_tag="VXC24_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492744.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSMLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        13256 a         9798 c         8058 g        12722 t
ORIGIN      
        1 caaaacattc ctccctatat ttttgattac caatcttaat catttacaac tacattctaa
       61 caaactataa aagcgtttgt cgaattgaat ttatcaagca agcaaccaac cagctcatct
      121 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
      181 aagcaagacg ataagagctc ctactcccaa gttgatggca aggatagggg agagagactg
      241 aaccaagaat atgctcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
      301 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
      361 tgacagattt ttaacgtcct taaagtaatg gtggcaagaa aggatgacac tggcaaggat
      421 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
      481 aagcaaagtc agaactggta aaaaggactg gacagcatat ataatccaaa atttcacttt
      541 cacataacga gcaaagtcaa agggtaaact cttaagaaaa tcaacatttt ccctctccaa
      601 ggacaaggca attgaatgca ggctggtgat attgttattg acaactgcta taaacactcc
      661 tacaaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
      721 gattttggaa atcagaccga tcatcatgag ataaggaaag aaagcacttg taaaaagcac
      781 tgtaaccacg ccagtaccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
      841 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
      901 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
      961 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctgtcgaaaa
     1021 aggatccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
     1081 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
     1141 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
     1201 agtttgagcc aagaaatgca ctgccactac catcactaga gccacagaga caaataataa
     1261 ggtcaaggac agtagcatca aaggcaaacc cagccataga gaaggagcta gcctaatgta
     1321 gaggaccaga aaataagcta ggattggtac aattccagtt agagctggca aaaggacaga
     1381 cagtccttta gcaattataa tctctgattc tttaaaggca tagggcctat acgatatcaa
     1441 atccttactc tcataaaaga cattgtaaaa ggccgttaaa gaagttgaaa aggcaatcac
     1501 tagtaaaata gcaatcatca agctaaaata aataggtatt tcctcaaaag gaaaatgaat
     1561 ggctatatta ctaaaacaga tgatcatcaa gagactggaa aaaatgtaag aacttaagac
     1621 tctagcggaa acatttactt ttttcccagg attcttagcc tgcttctttc gtagattagc
     1681 cagattagct tcttgagatg aataaaggat attgatatca actaattttt taatgacctt
     1741 gagacgcatc cgcaacctcc tcttttctac cagcaagact aaggtagata ctttccaaag
     1801 actggtctgg gtaatctttt ctcaagtcct ctacactacc acaataaatc aaatgcccct
     1861 ttttcaaaat ggcaatccga tcacagactt gctctgccac ctctaggaca tgagttgaaa
     1921 acaagactgt cttccctttt tgtgcatgtt ccttcatcat ctgtttcaaa tcaaaggcag
     1981 cctggggatc caaaccagtc aagggttcat ccaagaccca aatatcggga tcagacaaga
     2041 gtgctccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
     2101 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
     2161 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
     2221 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
     2281 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
     2341 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
     2401 cattttcaat ctgcaaattg agattactca aggccttttt atcaccatac aacttactaa
     2461 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
     2521 tagcactttg atacaaaaaa atcaatactt tattttaagt agttaaaata gtttccttct
     2581 atcttacgca aacgtttgcg ctaatagata ctttatgata gaataaagaa caagattgac
     2641 aagtaagagg aaacattatg caaaatcaaa cactcatgca atactttgaa tggtatctgc
     2701 cccacgacgg tcaacactgg acgcgtctgg ctgaaaatgc tccacaccta gctcatctgg
     2761 ggatcagtca cgtctggatg ccaccagcct tcaaggcaac caacgaaaaa gatgtcggct
     2821 atggggtcta tgacttattt gacttaggag agttcaacca aaaagggact gtccgcacca
     2881 agtatggttt caaagaagac tatcttcaag ccattcaagc ccttaaagcg cagggaattc
     2941 aacctatggc cgatgtggtt ctcaaccaca aggctgctgc tgatcacagg gaagcctttc
     3001 aagttattga agtggatcct gtagaccgta cagttgaact tggagaaccc ttcaccatca
     3061 atggctggac tagttttacc ttcgatggtc gccaagatac ctacaatgac ttccactggc
     3121 actggtacca cttcacaggt acagactatg atgccaaacg ccgtaagtct gggatttatc
     3181 tgatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
     3241 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
     3301 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
     3361 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
     3421 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
     3481 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc catcagaatc
     3541 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
     3601 tggttgaact caagcctgac aaggctgtga cttttgtcga caaccacgat acccaacgag
     3661 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
     3721 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
     3781 agtatgctca agaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
     3841 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
     3901 caggtgctga aaatcaatcc ccaatcgcag tccttatctc aaatgaccaa gaaaacagca
     3961 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
     4021 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
     4081 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
     4141 gcggatttgg cttttttgta ttcacaaaaa gacctaccca aatggataga tctttacttg
     4201 attacaattt acctgctact gcatccaaca attcttggat cttaggttgg ttgcttcctc
     4261 ctgccatggc catgtctggt ttaccaccac cacgtccatc gatgattggt gctaattctt
     4321 tgacaaggtt tcctgcatga aggtcttttg tcttgcttgc tacaaggaca ttgactttgt
     4381 caccgatagc ggcaactagg acaagaagat cagagtagtc tttttgtttc cagttatctg
     4441 caaaggtacg aagggcacct gcatcggata cagacacttg actagcaatg taacgatgac
     4501 cgttgacttc cttaacatct ttgaagatat cgcctgcggc tgcagctgcg gctttttctt
     4561 tcaactcagc attttctttt tgaagttgac gaagttgttc ttgaagtcct tctaccttgt
     4621 gaggtacttc cttgacttga ggtgctttca aggttgctgc gacagcttta agagcatcct
     4681 cttgttcacg ataggcttca aaggcttcct taccagtcac tgccaagata cggcgagttc
     4741 ctgaaccgat tccttcttct ttgacaattt tgaagagacc aatctcagaa gtgttgccaa
     4801 catgagtacc accacaaagt tcaatagagt agtcaccgat agtcacgaca cgaacttcct
     4861 tgccgtattt ctcaccaaag agggccatag ctcccatttc tttagcagtg tcaatatccg
     4921 tttcaactgt cttcacttca agtgcttccc aaattttctc gttaacttgc tgttcaatcg
     4981 cacgaagttc ctcagcagtt actgcttgga agtgggtaaa gtcaaagcga aggaattcaa
     5041 cttcgttaag agatcctgcc tgtgttgcgt ggtttccaag gatattgtga agggcagcgt
     5101 gaagcaaatg agtcgcagtg tggtttttca tgacacggtg acggcgattg ctatcaattg
     5161 ccaaggtata ttcttggttc aaggcaagcg gtgcaaggac ttcaactgta tgaagggctt
     5221 gaccatttgg ggctttctga acattggtca cagtagccac aatcttacct gactcatcca
     5281 agatttgtcc gtagtcagct acctgtccac ccatttcagc ataaaatgac gtttccgcaa
     5341 agataagaga ggcagttcct tctgaaacag ctcctacttc tgcattgtca gcaacgatag
     5401 ctaccaattt agaagacaat tggctagtat tgtagttgaa gacactttct acagtgatgt
     5461 tttgaagagt ttcattttgc atacccattg agccaccctt gacagctgac gcacgcgcgc
     5521 gttcttgctg ttctttcatg gctgcttcaa aaccttcacg gtctacagtc ataccagctt
     5581 cttcagcgat ttcttcagtc aattcaactg ggaacccata agtatcatag agtttaaaga
     5641 catcttgacc agcaatgaca gattgacctt tttctttcaa gtctgccaca atgccttggg
     5701 caaagtgttg acctgagtga agggtacggg caaatgattc ttcttcgctc ttaacgattt
     5761 tctcaataaa gtcacgtttc tcaagcactt ctgggtagta gctttccatg atttttccaa
     5821 cagttggaac caatttgtaa aggaaaggct cgttgatacc caatttttga ccatgcatag
     5881 aagcacgacg gagaagacga cgaagaacat aaccacgacc ttcatttcct ggaagggcac
     5941 catcaccgat agcaaatgaa agagaacgaa tgtggtctgc gataaccttg aagctcatgt
     6001 tgtcgccatc ttggtcataa accttaccag acaatttctc gacttcacgg ataatcggca
     6061 tgaagaggtc cgtttcaaag ttggtcttag ccccttggat aacggccacc aaacgctcca
     6121 aaccagcgcc cgtatcaatg ttcttatgtg gcaattcctt gtattcgcta cgaggaacag
     6181 cagggtctgc gttaaattgt gacaaaacga tgttccagat ttcaatataa cggtcgtttt
     6241 caatatcttc tgcaagcagg cgaagaccga tattttctgg gtcaaaggct tccccacggt
     6301 caaagaagat ttctgtatct ggtccagaag gtcccgcacc gatttcccag aagttgtcct
     6361 caattggaat caagtgactt ggatccactc ccacttcaat ccagcggttg taagaatctt
     6421 tatcgtctgg atagtaggtc atgtaaagtt tttcagcagg gaaatcaaac cattcagggc
     6481 ttgtcaaaag ctcataagcc caagtgatag cttcgtcacg gaagtaatcc ccgatagaga
     6541 agttccccag catttcaaac atggtatggt gacgcgcagt cttccctacg ttttcgatgt
     6601 cgttggtacg gatagccttt tgggcattgg taatacgtgg attttcaggg ataatggtcc
     6661 cgtcaaagta tttcttaagg gttgctaccc cagagttgat ccacaaaaga gttgggtcat
     6721 ttacaggaac caaacttact gatggttcta ctgagtgacc tttggtcgcc cagaaatcaa
     6781 gccacatttg gcgtacttgt gcactagata gttgtttcat attgtctcct tattcacttg
     6841 tttaatgtga ttggctttcc agcatttcca catagtcaat cgcgacacag agggaaatga
     6901 ctaggtctgc ataagcgtct tcaagaaccg ttacggtata ggtagaggtc agatggaaga
     6961 gttccttctt aatttccgca atcaactgat cgcgatcatc cagcaatttg aaattcaaat
     7021 cccagatatt gccctcgata cgaagaccta gattatcaaa ctcatactta tctcgccaga
     7081 aggtcaactt cttacgaatg acaaaactcg agccatcccg aagctgaatc tcaaaacgag
     7141 gaagcaaggt caagatttct ttactgatct gactgacttg ttcaccagcc gcatcataga
     7201 tggtaaaagt tttgggaatc ttaaaaaatg atccctccac ctgataggca atttctcccc
     7261 tgtcatcctt gatagcgaag cgttcgcctc caagacgaaa cttttgtttg acaagaaatg
     7321 ttttcatcaa cacctccaaa aatcaaaaga caagctcata tcacgaaggg cgaaaaaccg
     7381 cggtaccacc ttcattcaat gaacttgtca ttctcttgtt cttatgcaat tgtatgattg
     7441 agtagcatga cttcctagct tagatggctc gcagcaccgc catttctctg gactaagaca
     7501 agtgaaaatc aattctcaac tttcttatta taacgttttt ttaagcttgc gtcaactgga
     7561 aatgatctcc gttgaattag accaattccc tacatctctg attacttttt caggatatat
     7621 tttttcttac tgccattttt ctttttatcc caaattttca tattactaaa cacagctact
     7681 agaatatttc caaatataaa ggtgcctatc acccaatata tggactcagt tgttaggtat
     7741 tgtcgatcca agccatcatt taaatggaat agtatagcag tttggttaac aatcataaag
     7801 gttggccaga aacttttttt gaaaaaagta gacattttca ttatttgttg ccgctttctg
     7861 taaggttaat actcaataaa aatcaaaaag caaactagga agctagcctc aagctgtact
     7921 tgagtacggc aaggcaacgc tgacatggtt tgaagagtat aggcttagta tactactagg
     7981 caagcaaata agcaaataag caaataagca aataaacaac tagaatagaa aaagataggg
     8041 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
     8101 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
     8161 ccatttatgg tcaaatttct cataaacttc taggtgtttc atggtttcaa catcgggata
     8221 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta ggtttggtgt
     8281 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
     8341 aaaggcatag gctgagtttt ggtttttaac tgttttggga atgaccatat tgtcaaacca
     8401 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
     8461 gctggcttca ccagagaagg tcacgccgat tgcaacatta ttctgaatca tatagccctt
     8521 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
     8581 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
     8641 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
     8701 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
     8761 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
     8821 ctctgatccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
     8881 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
     8941 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
     9001 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
     9061 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
     9121 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
     9181 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
     9241 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
     9301 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
     9361 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
     9421 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
     9481 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
     9541 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
     9601 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
     9661 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
     9721 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
     9781 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
     9841 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
     9901 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
     9961 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    10021 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    10081 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    10141 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    10201 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatatcgt
    10261 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    10321 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    10381 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    10441 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    10501 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    10561 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    10621 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    10681 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    10741 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    10801 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    10861 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    10921 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    10981 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    11041 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    11101 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    11161 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    11221 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    11281 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    11341 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    11401 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    11461 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    11521 atcttgagaa cttccgctac gcgttgctcg atttctttct tgtcaatctt gcgcaagcga
    11581 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    11641 acagtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    11701 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    11761 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    11821 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    11881 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    11941 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    12001 gctttcaccc ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct
    12061 ttcacccaag atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc
    12121 gataaccgat tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat
    12181 aaatcctgca tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc
    12241 ttctgaaatt aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga
    12301 tgggtattcc aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt
    12361 gataacctga tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga
    12421 ctcctgaata gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat
    12481 ttctccatcc ttggtcaaga ccttacaaga ctgcaatatg tgagcaatct cgccaccata
    12541 ggcacccgca ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc
    12601 aaagccagtc aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc
    12661 ttctgcttca atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac
    12721 aaatccacga atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca
    12781 agggatattt tcttggttgg caaatttcac aaggcgagcc aactcaaaac gatttcgtgg
    12841 aaagaccaaa taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc
    12901 ctgaaaacgg atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc
    12961 actcttcctt ttacaaaatt cattccatta taccattttt agagacattt gacgaccata
    13021 aaaatacctt gtttggattt tgcataagaa aaagaggttc ccctcttttt atgatttttt
    13081 acaaaagatt tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc
    13141 aaccaagact ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa
    13201 ggcatgcaag ccataggctg ttaggagata aatccatttc ttctggcgaa cagcttgata
    13261 aacccaaact gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa
    13321 ataaatctgc cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg
    13381 cataacctgt ggattctgag tttgaactgc cgaaagaaca atgtaaagat tgagtaaact
    13441 agtaaggcct agaaaaatca actccaagcc accatgcccc aatccatagg ccaaggcgtc
    13501 tgccttttcc aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc
    13561 ctcaaaaaat gctaccatgg ctaggccata gataatatag ataagcggat gaacttacaa
    13621 gagggcaata ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa
    13681 aatctgcgaa gagacaaaga aagcgactgc acccaagtcc aagacagcta gattaatctg
    13741 gtatttcttt ttggcaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt
    13801 aataatgata tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat
    13861 ctcgtcaaca ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc
    13921 caactggtca actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg
    13981 tccaccgaag gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc
    14041 atggaaaatc tcaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata
    14101 ttccggttga tgggttgcga catcagcaaa cttggtatcg ggtgttgact taggaatcat
    14161 acgcacatgc atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc
    14221 atcataataa gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg
    14281 gaaaatgacc tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga
    14341 cacttccaca atttctggct ggtctcctga ccctttggcc tgataagcct tgccatccaa
    14401 gacaatcaat tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag
    14461 caattctcct actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt
    14521 gtattgaaat aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta
    14581 ttctataaat cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg
    14641 ctctagacat tgccaagaag gaaaaacagg gtacaatgta acaaaatcaa gggaggtctg
    14701 gaatgaagaa acaaagcaag tacaaagagg tcgtttccta tctgaaaaat ggtatcgagt
    14761 ctggacgatt tccgacgggt agcctgagat tttgacagaa acaaaacttg cactagcaca
    14821 acaaccccta aggaacacac ttccctaggg gtcgcttttt atttaactaa atcattattt
    14881 attttttgtt cctagtaaac ataaatattg tattaataat tgcaaaaata aatgcaaaca
    14941 aaaggatttt ccaaaggata aatttttgta acactaaata tgcatataca aatccaatca
    15001 aaaagctaat aatcccatct tttattaaaa agtttttatc acgcattatt ccagaccaca
    15061 ctgaactgcc caaatagcca actgaccagc aatgatataa atatttgttt taagtccatt
    15121 agctttaaca aatcttagta ccactttagc taattctgac caagcctttt tctgcgcata
    15181 cttaacaatt agcgaaacat tgatcatagc aaaaaattca tctcgtattt ttcctgctat
    15241 acatcctccc atctcatccc aagggactct gtcataggga ttattaatat tagtttctaa
    15301 ttcattttcc gcaagagcaa tatctttttg agaaaagttt ttataaacat attcagtaaa
    15361 atttttttca ttaactccat ttctaaacat ttgttcaaga acattggcta catcatcgat
    15421 ttgtttttgt tcttgggtac taatttcaga aacttccgta gtagttacat catcagcaaa
    15481 tactctaaca gaagctatag aaggagacat aatagaaaat agtgataata caacaagagc
    15541 tgaagttaca atttttttaa atttcataaa aaacactcct ttcaagtcac aaatatatat
    15601 tactgataaa ataacttgat tttctgattt aaaactcctt tctaacaagt tattcgtatg
    15661 cttttatttt ttagttctat tataccacaa caagaaaacg atttcaagca ttttcctaaa
    15721 aatatgtaca agtaatatgt acaagtaata aggggaaatt agcataaaaa ctttttaaaa
    15781 caaatcaacc ccagataaaa atacacatgt tgttttaaag acaaaaaagg gtacgaaaaa
    15841 ctgtcacatc tgcatttgat tgctctttga tttcaaaaaa gtattaaaaa tgggagtata
    15901 ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    15961 aaagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    16021 agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga cgggtagtcg
    16081 cctgccttct atccgtcaac tgagccttga ctttcactgc agcaaggaca ccattcaacg
    16141 agccctgctg gaattacggc acgaacaata tctctatgcc aagcctcaga gtggctacta
    16201 tgtattagaa caagggcaac atcaagacct agaaatcgag gttaccgacg aacatgccag
    16261 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    16321 cttcaactac tatgacaatc aagaaggatt agaagaccta agacagtcca ttcacaaact
    16381 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    16441 acaagccttg tttatcctct ctcaaatatc ctttcctaga caagccaagg aaatcttggt
    16501 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    16561 aacgattgaa cgaggcattg atgggattga cttggaggag ctggaaggcc acttcaaaac
    16621 aggaaaaatt aaatttttct acaccattcc tagatttcac tatcctctgg gacattccta
    16681 ttctgagcag gacaaacgat ctattcttaa cttagctgcc aagtatgatg tctatatcgt
    16741 agaggacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    16801 tacagaggag cgtgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    16861 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    16921 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    16981 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    17041 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    17101 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aactgggctt
    17161 ggacttcttt gaagaggcct atttaagcac ctgtccttat caatttgcca aggtgtccct
    17221 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    17281 gctttttctt attcttcaac ttcagttaaa cttgctgctt tttcaagata gctttggtaa
    17341 gttccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    17401 ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagct gacagttgcg
    17461 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    17521 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    17581 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    17641 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    17701 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    17761 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    17821 aaaacattat caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    17881 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    17941 aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt ttgcttaatg
    18001 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    18061 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctctc
    18121 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    18181 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    18241 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    18301 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    18361 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    18421 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    18481 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    18541 cccatttttt taatttcttc ctctacagct ggaatgcgct cttccccctt catacggatg
    18601 gttgcctgag caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    18661 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    18721 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttcgatgacc
    18781 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    18841 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    18901 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    18961 ccttgtgttg gggattaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    19021 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    19081 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    19141 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    19201 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    19261 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    19321 ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    19381 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    19441 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    19501 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    19561 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    19621 tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa atcgcatctg
    19681 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    19741 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    19801 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    19861 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    19921 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    19981 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    20041 taacctgatc ccaaagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    20101 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    20161 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    20221 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    20281 caatggtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gatcccgacg
    20341 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    20401 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    20461 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    20521 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    20581 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    20641 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    20701 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    20761 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa aacgacaccc
    20821 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    20881 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    20941 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    21001 gaaaatccat actcaaactg gactacaaag atcaagtaac caaagagacc caccaccact
    21061 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    21121 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    21181 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    21241 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    21301 atatagagaa tcaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    21361 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    21421 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    21481 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    21541 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    21601 aaccatctgg atagctagag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    21661 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    21721 tcccatagcg aaactggctt cacgataata acgaggaacc gcacgcaagc tatccgttgt
    21781 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    21841 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    21901 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    21961 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gtgttgcgat
    22021 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    22081 tttactagaa ggattccaag ttcctcccaa aagaaagtca aagatattca caccattgac
    22141 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    22201 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    22261 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    22321 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    22381 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    22441 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    22501 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    22561 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    22621 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    22681 acagtatcaa aggtagcacg agagccagag ccggctgccc gattgataac agagatgggt
    22741 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    22801 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    22861 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    22921 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    22981 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    23041 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    23101 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    23161 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    23221 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattgatt
    23281 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    23341 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    23401 ccctttttaa tgcaagggaa attactcttc ttagatgata atccaaaagc tagaaaggta
    23461 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttctatttta
    23521 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    23581 aaatctcttc aaagcagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    23641 ttttcatcga gtagtaaaac tacatgtgat ggcaatcaag atatcaagaa tcatcctact
    23701 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    23761 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    23821 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    23881 acggtttctc cagccgcata cttgacaaac gcttcttggc caatttcaac cgactgttcg
    23941 acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    24001 aaagtaccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    24061 tctggcaaga gataaagctg gtctccaaaa atctgcaaga tacccggtag attgaccttc
    24121 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    24181 cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc aacaaactga
    24241 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    24301 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    24361 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    24421 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    24481 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    24541 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    24601 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    24661 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    24721 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    24781 ataccaggac tgggttgggc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    24841 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    24901 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    24961 gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc tcctagtatt
    25021 tctttatatt tttcaacaaa tccttctgga aatttcattt aagttctttt cctttcgtaa
    25081 atataggact gaatttcctc ctgcatctca agaggcacca tcatgaccgg ctgtctggtt
    25141 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    25201 atactagctg cggcataatc ccatggttgc agataggtga gataggtcaa caaatgccct
    25261 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    25321 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    25381 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    25441 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    25501 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    25561 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    25621 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa aatctcacca
    25681 accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg agaggacttg
    25741 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actggcctgc tttcttaaca
    25801 agctctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    25861 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    25921 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    25981 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    26041 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    26101 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    26161 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    26221 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    26281 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    26341 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    26401 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    26461 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    26521 tactttgcta cttctattat acaaaaaaat aaagcgcttg actagggatt tttagaaaaa
    26581 aagcctattt tttcaagaaa aataggcttt ttgcgaacga ttgacacaat tggatttggt
    26641 taattcactc ttaacgatgg ttttaaacga tatatatttt tatatatgta aattaaaaac
    26701 atctttcctt tcacttccta cgacttttca gatacagata gccaaagaag ttttcataga
    26761 gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc tggcaaaatc ataataacag
    26821 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    26881 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    26941 ctactagagc caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    27001 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    27061 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    27121 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    27181 tggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    27241 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    27301 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    27361 tgtgtcggtg cgattggcag gccagctact tcttctgcct tagtaaaacc tgtcgtcacc
    27421 aagagcgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    27481 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    27541 gcatttggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    27601 agtgagccag cacctggcaa aagaccacgt tccgtcggga tgttgaggtc aggattggtt
    27661 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    27721 acttgccaat ccagaccaac taccacgtag gcagggtttt ccttgtcttc cacataacca
    27781 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacagt cttttcaagc
    27841 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgatagaggc
    27901 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgggttgta
    27961 ttgttggtta caaagagata gggaatgtcc cgcttttgca attcatgaac aaaagtctct
    28021 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    28081 ttatatttca tctatttctc cctaaacctt ttttatttct tgccaagtaa tgattgcttg
    28141 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    28201 agccgatgta atcaccccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    28261 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    28321 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    28381 gatcggctct tccaaggatt catacttcgg tccacggata agttttttat caaaatcaga
    28441 ctggtaagga gccacaatct caggttcaac agcatggact tttcgactgt cgcggtccat
    28501 gagaacaaag gtcgccatca tatggatgag ctcctgcccc gcttcattat aaatagtaaa
    28561 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    28621 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct gcgataatcc agaccagatt
    28681 atagtcttcc aaaatggcct tatcactaac tcccagttca atcgattgca tccctgaaac
    28741 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    28801 aaaaggaatt ttcattttca tttgataagt taagcacatg atcctactcc aaaataaatc
    28861 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    28921 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agtccagcaa
    28981 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    29041 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    29101 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttatagcgta
    29161 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    29221 acatgagatt gtgacgactt tcaaagccgg gtttggagaa attagaaatc tcataatgct
    29281 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    29341 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    29401 aaatcaaact atacaaactc atgtggggaa tatccagtcc aatggcttta gccacatttt
    29461 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    29521 caaaaccagc cagtttcagg cgatcgatat tttcataaat atccttctcc aaatgactgc
    29581 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    29641 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    29701 tggtcaactc ttccaagaca gacaagtcca agtttttagt caagccattc agtaacacct
    29761 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    29821 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    29881 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    29941 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    30001 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    30061 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    30121 ccattgctcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    30181 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    30241 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    30301 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    30361 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaacggttcc
    30421 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    30481 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    30541 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    30601 atctgcaaca gcactgaaga gtggatcaat cgtagccacc ttgacattga tatcatctgc
    30661 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ccacatctga
    30721 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    30781 aatgatcaga tagaccaaaa agacaatcaa agctagggca acaagaatat atgcaacttc
    30841 taacatttag ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    30901 aacgatcatt ataccgagac cgataaagac aactgacagc cattgggaca ctcgaaggct
    30961 gaagaacatg agactatctg ttcgcatacc ttcgatgacc atacgaccga aaccatacca
    31021 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    31081 cagaatcaag gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    31141 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    31201 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    31261 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    31321 agcaaagata tagagcacaa gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    31381 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    31441 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    31501 atcgtctggt atgatcttct ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat
    31561 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    31621 aattggatca agcattttgc acctcatttc gagctatgag acttgtcagt cgttcgtcga
    31681 acaaacgggt agcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    31741 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    31801 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgcgtatcgt
    31861 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    31921 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    31981 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    32041 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    32101 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    32161 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    32221 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    32281 gaaccaccaa accacgggca acaatgactg ctggtgtctc aggtagaaac atttttttca
    32341 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    32401 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    32461 gcgtaatatc cgctgtattg atttcctttt caagcaattc tggttcacca tagacaatat
    32521 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    32581 gaattcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    32641 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcatttc aattagaatt
    32701 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    32761 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    32821 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    32881 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    32941 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    33001 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    33061 gggtgatttt ggaggctact tgcaggtagg ttctcagtca ctgggccaga tactgttccg
    33121 gcaatggctt ctgctttcga ctcaccataa gcaaaaagaa taatagactt ggcatccaaa
    33181 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt ggcaaagaag
    33241 cgagcattgg cttcgatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    33301 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    33361 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    33421 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    33481 atgaagtaac gataagactg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    33541 acactggtta gatttgaaaa atcaaggtca ctctcaacaa tttccttgta aaattcaagt
    33601 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    33661 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    33721 tcatcctcca tttctgtcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    33781 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    33841 agaacttaga aagaatgaac aaatatatga atacagctga ttttgatttc cacttgccag
    33901 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    33961 accgtgagac aggagaaatg caagataaac atttccactc tattattgat atgctggaac
    34021 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    34081 aagtggagac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    34141 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    34201 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    34261 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    34321 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    34381 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    34441 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    34501 gacctgtttc tgtggataat ctggacgaac acgaaatgca ctcagagttc tatcaacttt
    34561 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    34621 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    34681 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aagatcgtgg
    34741 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    34801 ttgcaggccg tgaattagtc ttagatgcct accaccatgc catccaagaa cactaccgct
    34861 tcttcagttt tggtgacgcc atgtttattt attgagaaag aatttctcta attcttctaa
    34921 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    34981 tgtagaagac gcctagtaca ttgaaattaa aatgcttccc cctagcttcg aaaatattgc
    35041 catagattgc gttgactctc caaattgatt catctatatt ttatttcagc ttcctatatt
    35101 ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt agcaccatat ttgttactct
    35161 tatctgtcct ctcaagagac tattatgagt tatttcagaa tcattcacta ctttgaccct
    35221 gactctcctt agtctcaaaa tcaaagactt atactcttca aaaatctctt caaaccgcgt
    35281 caacgtcacc ttggattata tatgtgactg acttcgtcag ttctatctac aacctcaaag
    35341 cagtactttg agcaacctgc gactagtttt ctagtttgct ctttgatttt cattgagtat
    35401 taaacaaaaa gtgaacaaat ctgaattcta atgtacagaa gactaggctt gttcactttt
    35461 ttatagtcgc tataagatga ccttatctat agctttttat atataattat atattcagac
    35521 atactattat caattttgtc gcagggagga atctgttaac gcacccattc accattatca
    35581 ttgactctat agccatctat acttgtattg accgctaact cacccgatgc atttacataa
    35641 taccatttac caccaacttg gaaccattga ttgactttca tagaaccgtt gctgttgagg
    35701 tagtaccatg aaccattaac ttgtacccaa cctgttgcca tggaaccatc agtattataa
    35761 aaataccaca taccattttc ttgtttccag tctgttgttg gagcaactgc tttagctggt
    35821 tctactgcta catctgttcc ttggttagat gtaacagata caggatacga aggaatagat
    35881 gattgctcag gaacaacaac tttttcaggt tctctcgtcc ctctccttat acgtcttttt
    35941 accatctctt tagtaatttg acgagaagta gtttcttcaa ttattccatc acgttcatct
    36001 acagtataga ttgtagtaag agtaatttac caatttctcc tacttcttct acttcttgac
    36061 ttttatcaag agttgggcca tcgagatatt ctgtttcgat tggaatttct tggacaagaa
    36121 cttggggctt ggttcctttt ttaacaactc ttgtttgaga gtcttttttt gacttaaagt
    36181 actctcagtt acttgtccac tctttccatc tacattataa gttatcgttg taactgtttt
    36241 cccattcttt cctagagtaa tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc
    36301 atatttagta gcaaatggaa caagaacttc ttcaatcttg cttttagctg gaactttgat
    36361 aactgtatcc gtggcttctt ttctatcaac agtaacctgt tcggtaacat aaccagtctc
    36421 tggattaaca tcgtaggtcc ttgtcgtagt tacatagcca tcctctccgt caattgtaac
    36481 aggattttca ctacggtctt ttgtttcatc tttttcaaaa cgaattcgcg tacttgaaat
    36541 tttcttggtt actaccttag gtttagtcgc tacttttaca ataatatccc cattgtcagc
    36601 gtcatcatac tctattccct cttctttatc tctagtatca tctctgacat attgaatccc
    36661 atcagcagca tgagcaaaac ttgtattcag attcctccta aaaataaagt tagcccgatt
    36721 atcgcagaac caaaaatctt tccgagttta cgtattgcat aacgcttatt agtattagat
    36781 tttgccatta catcctactt ctagtatagc atcttttcta tcaaacgtta aacaatatac
    36841 tttatatata aaatagactt agaatgatat attgattatt gaactaacac tttaactata
    36901 tcgtaatcaa tctcatatat aaaggattgc agacatctga tctaaataca tgctaatata
    36961 tttagataca aacattccaa cttgataatt ttcactcatc tttcaacatt ccttacacaa
    37021 cgatgcagta taaatagaat agttttctca tcagaatgag actattttaa tattagataa
    37081 tttgatagaa aaacataaat aaaattggtt gaatttaatt ccctaactcg atagaggatt
    37141 ctattttaaa tttaacaaca gctaggatta cactataaaa agtacattac cacctgttcg
    37201 gctggagaat ctagtcgatt agctccctct tagttacaag cttaaagcga ttttttaact
    37261 aatactaaac cagattaaag aaggaactag aacatctgtc ttgtactaat caatatgcta
    37321 ttttaaaatt gcaaataaac ttggaatgct aattattata tttacaataa atagttgact
    37381 tcgatagaaa cagaaaatag aattcaacat tcttccctac ttataccata ataaataaga
    37441 tccgcaagat agccttttct ctctacacca ttaacaatgg tttgtagata ggacattcca
    37501 gccttttcca tgacacgacc tgaagctggg ttgagactgg cataacgtgc tctgaccttt
    37561 tgaaaacctg cttgagtaaa acaaaagtcc aagacagctt tcaaggcctc tgtcatcata
    37621 ccatgtcccc agtaagcctt gcctagcaca tagccgattt cacagcttaa atcagcctcg
    37681 tctatcttaa cgatgctgat atctcctatc acttgctctg ggttttcttt tagacaaatg
    37741 gcccatttgt aatagttgag attagtatag gaagcaaccc aattgcgaat cgagtttcga
    37801 gtgatttcga catcaggatg gggatcccag gtaacatagg tcagattctc agtggatgaa
    37861 gcccaatttt gaaacatggc ttctgcatca ctctccacaa atcttcttaa aatcaaacgt
    37921 tctgtctgta atatttgcgt accgatagat ttcatgatgc tacctcactt ccttatttct
    37981 atactcgtag taagaaggct caactcagta acagctagaa aacgagtttg tcttctaatt
    38041 tcttgacgca gttgctgcct ggtttgaaat gcgctctagc aagctttttc aaacctagtc
    38101 atcgttgcag gggtaagacg atgaaatcga actcttcgag ttactgaatc tgcctcattt
    38161 tcttatttct aaactcgggg ttcaagatcc cccagacctt ctctcacttt cttatttcaa
    38221 gatgagaggc tgaaaacctc cactggaggt ttttcttgct ttttaatttc agggcaagaa
    38281 gctaaaaagg tcccccggac cttcttcgct ttctcatttc taggctcagg gtaaaaacct
    38341 ccagtggagg tttttactcc caaaagtcat caaatacagt gatgggtaag tggcgtttgt
    38401 gttggccttt gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg attgttttgc
    38461 cttctaggta gtcgtcaatc tctgcgtagg tgactccaag tgcgacttcg tcagctaggc
    38521 ctggtttatc ttcttctagg tctgccgttg ggattttttc ataaagggct ggctctgcgc
    38581 caagtttctg caagagctgt tttccttggc gtttattgag gcggtaaaga gggagaatat
    38641 ccgcaccgcc gtcaccaaac ttggtaaaga aacctgtgat attttccgcg gcgtggtctg
    38701 ttccaatgac cgctccgcta tgggaaccag caagggcata ctgagcaatc atacggcaac
    38761 gtgccttgat attccccttg ttgaagtctg aaacaggact acctgtcgct tcaactgcag
    38821 ctgtcatggc atcagctgat tccttgatat tcacaaccaa gctgacatct ggctggatga
    38881 aggctagggc tttttgagca tctgcttcat cagcttgcac tccgtatggc aggcggacag
    38941 cgataaattt gtagctatcg tctcccgttt cagctcgcag ttcttccata gctaattgcg
    39001 ccaaacgtcc tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca aaggttttta
    39061 ggaagggatg ttttttcaga tatcttttta agaaatcaat agaacgacgg atttcttcct
    39121 gggcatcaat cactggtttg acacccagct cttggataat cgtttcttgc aaactcattc
    39181 ttcttctcct tcaccaaggg cttccttgcg catcttatca atcaagtcca tcttatcttg
    39241 ccatacatca cgcgccaaat ccactggata gtgctgcgga ttgagcacac gcttatactc
    39301 atcccacaac ttgtcaaatt ccttacgggc ataatcctga atgtcagtca aactaggcaa
    39361 gttgtaaact aatattcctt ctttgaagat atccaccaag agaggaacgg catcaaaatt
    39421 acgaaccgtc ttcttgatgt atgtataggt cggatggaac atcttgattt ctgtcatgtc
    39481 gctaatatcc acaccatcat aagtgatgta gtcaccttct gacttgcctt tttcacgact
    39541 ggtaatgcgc cacacctgct tcttacctgg cgtcgacact ttttccgcat tattagacag
    39601 cttaatcgta ttgcgcatct ggccgttttc atcttcgatt gcaacaatct tgtaaaccgc
    39661 cccaagagcc ggctggtcat aggctgtaat cagcttggta cccacacccc agacatcaat
    39721 cttggccttt tgcatcttga ggttaaggat ggtattttca tctagatcat tagaagcata
    39781 aatcttagcc tctggaaatc cagcctcgtc cagttgctga cggactttct tagaaatgta
    39841 ggcaatatcc ccagagtcaa tccgcacacc cataaagtta atctgatcac ccagctcacg
    39901 cgccacctga atggcagctg gtacaccgat gcgaagggta tcataggtat ccacaagaaa
    39961 gacacaattt ttgtgggtcg cagcgtaagc cttgaaagcc tcatagtcat tgccataaac
    40021 ctgtaccaag gcatgggcat gggttcccaa aacaggaatg tcaaagagct tacccgcacg
    40081 cacgttgctg gttccattgg cgccaccaat caccgctgcg cgtgttcccc agatggccgc
    40141 atccatttct tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt cgataaccga
    40201 acgaatacga gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc
    40261 cgtttcgacc aactgacatt gggctagagg tccttccacc tgcacaatcg gttcattagc
    40321 aaaaaccaaa tccccttctt gggcagaacg aacggtcaac tccaacttga aattgcgaag
    40381 gtaatccaag aacgccccat gataaccaag cgactccaaa taggctatat cactatctga
    40441 aaaacgcaag tcttcaagat agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc
    40501 gttcttaaaa ggctgttggc ggaaatacac ctcaaagacc gccttcttat tgtaaatccc
    40561 ttgatcaaag taaacctgca tcatgttgat ctggtacaag tccgtgtgca atgtcaaact
    40621 atcatctgga tacatacttt tcctacttcc ttagctagaa acccatgaaa attttcaaga
    40681 actttcatgt attccaataa attagtacta ttatatcaca ttttagctgg attgagaaaa
    40741 gagtaacaag ctattctcca ctctccaatt catccatatc ttgttcaaat tttttctgag
    40801 cccattcgcc atagctctta agaccaagat tgccaataaa gacccacgga aggtaaatga
    40861 cataagtaat gacccaagca gacaggtatt taaaattcaa aggattgtgc tgataaattt
    40921 ctatgttgaa ttgataattc tgcaacatca aaagagccgt aatagccaag gttaggaaaa
    40981 aacaacccaa aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga taacgggcac
    41041 gattgaaaaa gtaaaatgtc cctatgatga taacgattag cagcatatta gaattaaaaa
    41101 ggcttggtgc taatactgaa atgatataag ataggagcga caaagcaatg cagatataga
    41161 aactttcaga gcccgcttta ttgaacagtt gttcttctct ttcgtctagt aattgataat
    41221 aataaaatct atttttcatc ttcttcctcc caaaatagtt ggtctagggt tttccctaaa
    41281 catctgcaaa tagactggca gagcgagaga ctgggattgt attttcccgc ctctatcaaa
    41341 ccaatagtct ggcgtgtcac cccgacagcc tctgccagtt gaccttgtgt taaatcacgc
    41401 tctacccgag ctaattttaa ttttaaattt ttagccacct tcgtcctcct tatagtttta
    41461 atactcatct actcttaaaa aatccaaaac caacacaagc tatcagctat ttattataac
    41521 cccattaatt tgcactccag tattatcttc agccgaaaat cagtatttta ggttgtttga
    41581 aataaacttc ctagtttact cttttatttt tatttagtat tagctttagt aggatctttt
    41641 aaacgagttt ttattgctta tatttcttgt ttagtttagt tggtttcata tcactattat
    41701 ataatgcttt tggaaatgag cctagtataa gtcaaaaacg tgttgaatag tgaaagcagg
    41761 agcataccaa gatgactgat tttttactgt attttaggta tgcaaaataa tactaaatga
    41821 aactaaaatg aatacttctt gcttttcttg agagtgaaaa agtacaataa aatgattgta
    41881 gtgattagca caagatactg actaatagac atcgtatttg aagccacaaa tacaggtaaa
    41941 gaataaaaag gaagaagttc aattgctttg ataaacaaat cattactagt attcatcatc
    42001 atcgtattta atatattagg gataaagagt agtaaagcta ctaaaatacc aaataccaag
    42061 ccacttttca atttgtataa atagaaaatg taggataata gaaaataaaa caggactaac
    42121 aaaattgtat tgactacaat agctactata aaatctaatc ctaaatcacc tggaataccc
    42181 aatttactta ctatgactag taacacaatg ccattccaag cataaataat ggaaactgag
    42241 atggcatata gaaaattaga caagacgtaa atcatccgat tcttctgttg attataaaac
    42301 aaacttaccg tattgtggga aaaatctcta ctaatgactc gattagcatg tataacagcc
    42361 attaacatac cgagcatggc ataaaagttt gaaatatgct taataccaag cgatgtccct
    42421 tgagtcttta gaataaagaa tgtaagcaat atcggcggta taaacgagat aagcaaactg
    42481 agatatatta cgcctgatga atataaattt cttatacttt ccttaagaaa attcaattta
    42541 tttaatttca tgattataac cttcctttat tttgaacgat ttaggtaaat atctttaagc
    42601 gtctcttttt tagtttcaaa atcaactact ttaatagagt tttcgttaaa aaatttaaaa
    42661 agctcactac tttgaatatt cccagacata gtaattctca gtccctcttc ctgaacaata
    42721 tctccaaatt cttgtttggt aatgaaaatg tctctatctg tagctgatga aaaagctatc
    42781 tcaaacaaga aattatgact atcttttcct actttttgaa atgtcaaaag cccgctctcc
    42841 aagaaaagaa ccctctcaca aatttcttca atatcttcta atttatgact cgatattaaa
    42901 attcccacat tttcatgtaa agctaaattt tttagaaccg ctaaaactat ttgtgatgat
    42961 tcaatatcta aaccattagt cggttcatct aaaatcaata tatcaggttc cgtaacgaga
    43021 gttagaagca aagctaattt ttgttttgta cccaaagaat aggtctttac ttttttatta
    43081 atagactgag tcaaatctaa ctcttggatc aaacttctaa atctttcttg attgtagtca
    43141 acaccatata aatttgacaa atattttaaa ttctctaaac ctgttttaga taaaaataat
    43201 tttggttctt cgattaaata cccaatatta tcactgctta taatattacc tgaagtcggt
    43261 tgattattct gagcaagaat tttcatcaac atactcttac caactccatt tctccctact
    43321 agaccaacaa tttcaccctt gttaagtgca aaatttatgt ctttgagaat gattgaatga
    43381 ccataatgct tacttacatt tataacttac attttttatt cctccattaa tattcatggt
    43441 ttgctctttg attcttattg agtttaaaaa gttgcgcctc tttttaacaa cattatatca
    43501 tatatctaac ttaatgcaat atataaatat cattttgtaa aattttatta acaaaaaact
    43561 ctctacaaca aaataataga gagttttctg cttattaatt tttttcaaaa tatctaagac
    43621 atcacttctt tgtttaattt gataggcttt gatacctaag ctccgacttt atcacttaaa
    43681 aaataaaaaa ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg
    43741 tttaagtgtt gtatatggag ctttgcataa ttttttaaaa ctaaacaact acattaagca
    43801 cgaactgtga cgctggttcc atcttcctta taaa
//
LOCUS       DAVLBN010000011        42459 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLBN010000011 DAVLBN010000000
VERSION     DAVLBN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.011"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(515..607)
                     /locus_tag="VXC24_000582"
     CDS             complement(515..607)
                     /locus_tag="VXC24_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0492745.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            768..1739
                     /gene="ruvB"
                     /locus_tag="VXC24_000583"
     CDS             768..1739
                     /gene="ruvB"
                     /locus_tag="VXC24_000583"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0492746.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1720..2292
                     /locus_tag="VXC24_000584"
     CDS             1720..2292
                     /locus_tag="VXC24_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0492747.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2523..3281
                     /locus_tag="VXC24_000585"
     CDS             2523..3281
                     /locus_tag="VXC24_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0492748.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3290..4093
                     /locus_tag="VXC24_000586"
     CDS             3290..4093
                     /locus_tag="VXC24_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0492749.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4115..5374
                     /gene="rseP"
                     /locus_tag="VXC24_000587"
     CDS             4115..5374
                     /gene="rseP"
                     /locus_tag="VXC24_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0492750.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5387..7240
                     /locus_tag="VXC24_000588"
     CDS             5387..7240
                     /locus_tag="VXC24_000588"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0492751.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7339..8718
                     /gene="bglA"
                     /locus_tag="VXC24_000589"
     CDS             7339..8718
                     /gene="bglA"
                     /locus_tag="VXC24_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0492752.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            8911..10719
                     /gene="glmS"
                     /locus_tag="VXC24_000590"
     CDS             8911..10719
                     /gene="glmS"
                     /locus_tag="VXC24_000590"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0492753.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(10857..10934)
                     /locus_tag="VXC24_000591"
                     /pseudo
     CDS             complement(10857..10934)
                     /locus_tag="VXC24_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            10991..12040
                     /locus_tag="VXC24_000592"
     CDS             10991..12040
                     /locus_tag="VXC24_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0492754.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(12140..15976)
                     /gene="spuA"
                     /locus_tag="VXC24_000593"
     CDS             complement(12140..15976)
                     /gene="spuA"
                     /locus_tag="VXC24_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0492755.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            16393..16806
                     /gene="rpsL"
                     /locus_tag="VXC24_000594"
     CDS             16393..16806
                     /gene="rpsL"
                     /locus_tag="VXC24_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0492756.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16826..17296
                     /gene="rpsG"
                     /locus_tag="VXC24_000595"
     CDS             16826..17296
                     /gene="rpsG"
                     /locus_tag="VXC24_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0492757.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17721..19802
                     /gene="fusA"
                     /locus_tag="VXC24_000596"
     CDS             17721..19802
                     /gene="fusA"
                     /locus_tag="VXC24_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0492758.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19906..24297
                     /locus_tag="VXC24_000597"
     CDS             19906..24297
                     /locus_tag="VXC24_000597"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0492759.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24399..24662
                     /locus_tag="VXC24_000598"
     CDS             24399..24662
                     /locus_tag="VXC24_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0492760.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24655..24933
                     /locus_tag="VXC24_000599"
     CDS             24655..24933
                     /locus_tag="VXC24_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0492761.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24954..25106
                     /locus_tag="VXC24_000600"
     CDS             24954..25106
                     /locus_tag="VXC24_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492762.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            25128..26369
                     /locus_tag="VXC24_000601"
     CDS             25128..26369
                     /locus_tag="VXC24_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0492763.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26379..26609
                     /locus_tag="VXC24_000602"
     CDS             26379..26609
                     /locus_tag="VXC24_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0492764.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            26832..27554
                     /locus_tag="VXC24_000603"
     CDS             26832..27554
                     /locus_tag="VXC24_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0492765.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27771..29105
                     /gene="pepC"
                     /locus_tag="VXC24_000604"
     CDS             27771..29105
                     /gene="pepC"
                     /locus_tag="VXC24_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0492766.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(29161..30072)
                     /locus_tag="VXC24_000605"
     CDS             complement(29161..30072)
                     /locus_tag="VXC24_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0492767.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(30096..30899)
                     /locus_tag="VXC24_000606"
     CDS             complement(30096..30899)
                     /locus_tag="VXC24_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0492768.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30927..31916)
                     /gene="manX"
                     /locus_tag="VXC24_000607"
     CDS             complement(30927..31916)
                     /gene="manX"
                     /locus_tag="VXC24_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0492769.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(32149..33168)
                     /gene="adhP"
                     /locus_tag="VXC24_000608"
     CDS             complement(32149..33168)
                     /gene="adhP"
                     /locus_tag="VXC24_000608"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0492770.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(33507..34319)
                     /locus_tag="VXC24_000609"
     CDS             complement(33507..34319)
                     /locus_tag="VXC24_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0492771.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            34509..35927
                     /locus_tag="VXC24_000610"
     CDS             34509..35927
                     /locus_tag="VXC24_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0492772.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            35980..36687
                     /locus_tag="VXC24_000611"
     CDS             35980..36687
                     /locus_tag="VXC24_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0492773.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            36812..37756
                     /gene="folP"
                     /locus_tag="VXC24_000612"
     CDS             36812..37756
                     /gene="folP"
                     /locus_tag="VXC24_000612"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0492774.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            37758..39080
                     /locus_tag="VXC24_000613"
     CDS             37758..39080
                     /locus_tag="VXC24_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0492775.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            39061..39615
                     /gene="folE"
                     /locus_tag="VXC24_000614"
     CDS             39061..39615
                     /gene="folE"
                     /locus_tag="VXC24_000614"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0492776.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            39658..40470
                     /gene="folK"
                     /locus_tag="VXC24_000615"
     CDS             39658..40470
                     /gene="folK"
                     /locus_tag="VXC24_000615"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0492777.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(40621..40938)
                     /locus_tag="VXC24_000616"
     CDS             complement(40621..40938)
                     /locus_tag="VXC24_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0492778.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            41295..41741
                     /gene="rplM"
                     /locus_tag="VXC24_000617"
     CDS             41295..41741
                     /gene="rplM"
                     /locus_tag="VXC24_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0492779.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            41760..42152
                     /gene="rpsI"
                     /locus_tag="VXC24_000618"
     CDS             41760..42152
                     /gene="rpsI"
                     /locus_tag="VXC24_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0492780.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
BASE COUNT        12073 a         8193 c         9835 g        12358 t
ORIGIN      
        1 taatctccct taactccacc caatcaggtg gagtttttta gctctatttc aggcttttgg
       61 ggactattct aaaaataatt tttcgatatt tttcggtatt tttcggattt tggtcgggga
      121 attggcgggg acttttttag cgaatataac taagaaatag gtctgtggtc gcttcagcta
      181 gttcaaactc aatttgattg taagtgactg ttaattgaag aactggaact actgtaataa
      241 tgattttgct tgtctagtag tggcgtatta aatgagaagt gacatgtaag attgtctctt
      301 cgtttacgaa atcaaaattt ctatgaaatt gatagaatcc ctaacgttct cttaatctta
      361 accgtcttgt cgtacagcgg ttgaagaaaa tgtaaacctt tgacaaaatt cgtgaactat
      421 gagataataa aaaggaattg agtactagtt ctatatcata ggctagaaaa gaccccaagc
      481 tcacgaccaa ataagcttgg ggtctttttt gacactattt gtccttgttt agccatttat
      541 cgactatacg aagaacgaca ccgaccacaa ttggtccgat gatagttttg agtactaatt
      601 ccatcatggg ctatctcacc tcctttcgta ggcggtgtag cagtgtcgta gaatattata
      661 ccacataagt gctaaactta ggagtcaccc aatcaggtgg cttttttgtt tgtggcttgg
      721 ttttttgata taatagagcc atgagtagaa ttttagataa tgagataatg ggggatgagg
      781 agttagtaga acgcacgctc cgtcctcagt atttacgtga atatatcgga caggataagg
      841 tcaaggacca gctacaaatc tttattgaag ctgccaaaat gcgggatgaa gcgctggatc
      901 atgtgctctt atttgggcct ccaggtctcg ggaaaacgac catggccttt gttattgcca
      961 acgaactggg agtcaatctt aagcagacgt cgggtccagt cattgaaaaa gccggagatc
     1021 tggtagctat tttgaatgag ttagagcctg gggatgtact ttttattgat gagatccatc
     1081 gtttgccaat gtcagtggaa gaggtgcttt atagtgctat ggaggacttc tacatagata
     1141 ttatgattgg ggctggtgag ggtagtcgta gtgttcattt ggagttacca ccttttacct
     1201 tgattggtgc gacgactcgg gctggtatgc tctccaatcc gctacgggca cgttttggga
     1261 ttacaggcca tatggagtat tatgcccatg ctgacttgac agaaattgtc gagcggacgg
     1321 cagatatttt tgagatggaa atcactcatg aggcagcatc tgagttggcc ctacgtagtc
     1381 gtgggacccc tcgtattgcc aatcgtctcc tcaagcgcgt gcgcgatttt gcccagataa
     1441 tggggaatgg ggtaattgat gatattatta ccgataaggc tttgactatg ctggatgttg
     1501 accatgaagg tttggactat gtggatcaaa aaatccttcg taccatgatt gagatgtaca
     1561 gtggaggacc tgttggtcta ggaactcttt ctgtgaatat cgccgaagag cgtgagacag
     1621 ttgaagatat gtatgagcct tacttgattc aaaaaggttt tatcatgcgg acacggtctg
     1681 gacgggtggc gactgctaag gcatatgagc acttaggtta tgaatacagt gaaaaataag
     1741 caagaaatct tagaggcttt tagagaaaat ccagatatga tggccattct gacgatcatc
     1801 cgagaccttg gtctgaaaga ctcgtggttg gcagcaggtt ctgtcagaaa tttcatttgg
     1861 aatcttttgt cagacaaatc cccttttgat catgaaacag atatagatgt gattttcttt
     1921 gatccagatt tttcttatga ggaaacctta ttactggaga aaaagctgcg agaggatttt
     1981 cctcagtacc agtgggaatt gaaaaatcag gtctatatgc atcagcacag tcctcacact
     2041 gcttcctata ccagttctcg tgatgctatg agtaagtatc cagaacggtg tacgacagtt
     2101 ggactgcgct tgaatgaaga atcagatttt gaactctatg caccttatgg tttggaggat
     2161 attttgaatt ttcaagttcg tccaactcct catttcttag aaaatgaaga ccgaatggaa
     2221 ctctatcaaa cacgtttatc caagaaaaat tggcaggaga aatggaaaaa tttgattttt
     2281 aaaaatactt aaggaaactt taagctaggg agtgtacact aagttcataa gttaagaaga
     2341 ccttaactta aactcctaaa actttttcat aataatctcc ctataaaaat aaagtcgccc
     2401 aatcaggcgg cttatttttt tgaaaaatgg gcttggtgcc tgagaataaa tagcttagtg
     2461 atagaagaaa atggggaaat atggtataat aaaacgatag atttttgaat aggaataaga
     2521 tcatgtttgg attttttaag aaagataagg ctgtggaagt agaggttccg acacaggttc
     2581 ctgctcatat cggcatcatc atggatggca atggccgttg ggctaaaaaa cgtatgcaac
     2641 cgcgagtttt tggacataag gcgggcatgg aagcattgca aaccgtgacc aaggcagcca
     2701 acaaactggg cgtcaaggtt attacggtct atgctttttc tacggaaaac tggacccgtc
     2761 cagatcagga agtcaagttt atcatgaact tgccagtaga gttttatgat aattatgtcc
     2821 cggaactaca tgcgaataat gttaagattc aaatgattgg ggagacagac cgcctgccta
     2881 agcaaacctt tgaagcttta accaaggctg aggaattgac taagaacaac acaggattga
     2941 ttcttaattt tgctcttaac tatggtggac gtgctgagat tacacaggcg cttaagttga
     3001 tttcccagga tgttttagat gccaaaatca atccaggtga catcacagag gaattgattg
     3061 gtaactatct ctttacccag catttgccta aggacttacg agacccagac ttgattatcc
     3121 gtactagtgg agaattgcgt ttgagcaatt tccttccatg gcagggagcc tatagtgagc
     3181 tttattttac ggacacctta tggcctgatt ttgacgaagc ggccttgcag gaagctattc
     3241 ttgcctataa tcgtcgtcat cgccgatttg gaggagttta ggaggaaata tgacccagga
     3301 tttacagaaa agaaccttgt ttgcagggat tgccctggct attttcctac caattttaat
     3361 gattgggggc ctcttgcttc agatagcaat cggaatcata gccatgctag ccatgcatga
     3421 acttttgaag atgagaggtc tagagaccat gacgatggag ggcctcttga ccctctttgc
     3481 aacctttgca ttgaccattc ccttggagaa ttacctgact tttttgccag ttgatgggaa
     3541 tgtggttgcc tatagtgttt tgatttcaat catgttagga acgaccgttt ttagcaagtc
     3601 ttatacgatt gaggatgcgg ttttccctct tgctatgagc ttctacgtgg gctttggatt
     3661 taatgcttta ctagatgctc gtgttgcagg tttggacaag gctctcttag ccttgtgtat
     3721 cgtctgggcg acagacagtg gtgcctatct tgttgggatg aactatggga aacgaaagtt
     3781 agcaccaagg gtatcgccta ataaaaccct tgagggtgcc ttgggtggta ttttaggagc
     3841 aattttagta accattatct ttatgatagt tgacagtaca gttgctcttc catatggaat
     3901 ttacaagatg tcagtctttg ctattttctt tagcattgct ggacaatttg gtgatttact
     3961 agaaagttcg atcaaacgtc attttggtgt taaggattct gggaaattta tccctggaca
     4021 tggtggtgtt ttggatcgtt tcgatagtat gttgcttgta tttccaatca tgcacttatt
     4081 tggactcttt taatcaaaag acggaggaaa cgctatgctc ggaattttaa cctttattct
     4141 ggttttcggg attattgtag tggtgcacga gttcgggcac ttctactttg ccaagaaatc
     4201 agggatttta gtacgtgaat ttgccatcgg tatgggacct aaaatttttg ctcacattgg
     4261 caaggatgga acggcctata ccattcgaat cttgcctctg ggtggctatg tccgcatggc
     4321 cggttggggt gatgatacaa ctgaaatcaa gacaggaacg cctgttagtt tgacacttgc
     4381 tgatgatggt aaggttaaac gcatcaatct ctcaggtaaa aaattggatc aaacagccct
     4441 ccctatgcag gtgacccagt ttgattttga agacaagctc tttatcaaag gattggttct
     4501 ggaagaagaa aaaacatttg cagtggatca cgatgcaacg gttgtggaag cagatggtac
     4561 tgaggttcgg attgcacctt tagatgttca atatcaaaat gcgactatct ggggcaaact
     4621 gattaccaat tttgcaggtc ctatgaacaa ttttatctta ggtgtcgttg ttttttgggt
     4681 tttaatcttt atgcagggtg gtgtcagaga tgttgatacc aatcagttcc atatcatgcc
     4741 ccaaggtgcc ttggccaagg taggagtacc agaaacggca caaattacca agattggctc
     4801 acatgaggtt agcaactggg aaagcttgat ccaagctgtg gaaacagaaa ccaaagataa
     4861 gacggcaccg actttggatg tgactatttc tgaaaagggg agtgacaaac aagtcactgt
     4921 tacacccaaa gatagtcaag gtcgttacct tctaggtgtt caaccggggg ttaagtcaga
     4981 ttttctatcc atgtttgtag gtggttttac aactgctgct gactcagctc tccgaattct
     5041 ctcagctctg aaaaatctga ttttccaacc agatttgaac aagttgggtg gacctgttgc
     5101 tatctttaag gcaagtagtg atgctgctaa aaatggaatt gaaaatatct tgtacttctt
     5161 ggcaatgatt tccatcaata ttgggatttt taatcttatt ccgattccag ccttggatgg
     5221 tggtaagatt gtgctcaata tcctagaagc catccgccgc aaaccattga aacaagaaat
     5281 tgaaacctat gtcaccttgg ccggagtggt catcatggtt gtcttgatga ttgctgtgac
     5341 ttggaatgac attatgcgac tcttttttag ataatcgagg aatattatga aacaaagtaa
     5401 aatgcctatc ccaacgcttc gcgaaatgcc aagcgatgct caagttatca gccatgctct
     5461 tatgttgcgt gctggttatg ttcgccaagt ttcagcaggt gtttattctt atctaccact
     5521 tgccaatcgt gtgattgaaa aagctaaaaa catcatgcgc caagaattcg aaaagattgg
     5581 tgctgttgag atgttggctc cagcccttct tagtgcagaa ttgtggcgtg aatcaggtcg
     5641 ttacgaaacc tatggtgaag acctttacaa actaaaaaac cgtgaaaaat cagactttat
     5701 cttaggtcca actcacgaag aaacctttac agctattgtc cgtgattctg ttaaatctta
     5761 caagcaattg ccactcaacc tttatcaaat tcagcccaag tatcgtgatg aaaaacgccc
     5821 acgtaatgga cttcttcgta cacgtgagtt tatcatgaag gatgcttata gtttccacgc
     5881 taactatgat agtttggata gtgtttatga tgagtacaaa gcagcctatg agcgtatttt
     5941 tactcgtagt ggtttagact tcaaggctat tattggtgac ggtggagcca tgggtggtaa
     6001 ggatagccaa gaatttatgg ccattacatc tgctcgtaca gaccttgacc gctgggttgt
     6061 cttggacaag tcagttgcct catttgacga aattcctgca gaagtgcaag aagaaatcaa
     6121 ggcagaattg ctcaaatgga tagtctctgg tgaagatacc attgcttact caagtgagtc
     6181 tagctatgca gctaacttag aaatggcaac aaacgagtac aaaccaagca accgtgttgt
     6241 cgctgaagaa gaagttactc gtgttgcaac gccagatgtt aaatcaatag atgaagttgc
     6301 agctttcctc aatgttccag aagaacaaac gattaaaacc ctcttctaca ttgcagatgg
     6361 tgagcttgtt gcagcccttc tagttggaaa tgaccaactc aacgaagtca agttgaaaaa
     6421 ccacttagga gcagatttct ttgacgttgc tagcgaagaa gaagtggcga atgttgttca
     6481 agcaggattt ggttcacttg gaccagttgg tttgccagag aatattaaaa ttattgcaga
     6541 tcgtaaggtg caagatgttc gcaatgcagt tgtcggtgct aacgaagatg gctaccactt
     6601 gactggtgtg aacccaggcc gtgattttac ttcagaatat gtggatatcc gtgaagttcg
     6661 tgagggtgaa atttccccag atggacaagg tgtccttaat tttgcgcgtg gtattgagat
     6721 cggtcatatt ttcaaactcg gaactcgcta ttcagcaagc atgggagcag atgtcttgga
     6781 tgaaaatggt cgtgctgtgc caatcatcat gggatgttac ggtatcggtg tcagccgtct
     6841 tctttcagca gtgatggagc aacacgctcg cctctttgtt aacaaaacgc caaaaggtga
     6901 ataccgttac gcttggggaa tcaatttccc taaagaattg gcaccatttg atgtgcattt
     6961 gattactgtt aatgtcaagg atgaagaagc gcaagccttg acagaaaaac ttgaagcaag
     7021 cttgatggga gctggttatg aagtcttgac agatgaccgt aacgaacgtg tcggtgttaa
     7081 atttagcgat agtgacttga ttggtcttcc aatccgtatc actgttggta aaaaagcggc
     7141 cgatggcatt gtagaagtta agatcaaggc aactggtgac accattgagg ttcatgcaga
     7201 taacgtgctt gaaacgcttg aaatcctaag taagaaataa aaactataat cagaagaaaa
     7261 acaaggaaaa aatgtaacta gtttttacct tgttttttct gtataatggg agaaatgagt
     7321 agataaagag gtaaatgtat gctaagattt ccaaaggatt ttgtctgggg atcctctact
     7381 tctggaccgc agacagaagg acgtgtagct ggtgacggta agggagacaa tctctgggat
     7441 tactggttcc aagtggagcc aaatcgttac tataatggga ttggttcaga taagacatcg
     7501 actttttatg aaaattggga gcgggatatt gagcttttgt tagagactgg tcacacagcc
     7561 tttcggactt ctattcagtg gtcacggatt tttccacaag gctgtggaaa agtcaaccct
     7621 caaggtgtgg atttttatcg taaggtcttt gaggctatta aggctaaagg aattcgtctg
     7681 ttagtcaatc tctatcattt tgatttacct tttgcccttc aagaggatgg tgatggttgg
     7741 gaaaataagg cgacagtttc agcctatgaa gactatgctc gtttttgttt tgagacttat
     7801 ggagatttag tggatcaatg gattaccttt aacgagccca tcgttcctgt agaatttggt
     7861 tatttttatg atgcccatta tccacataag gtggatgcag aggcagctgt taaggtagcc
     7921 tatcatacac aattggccag cagccgggct gttaaggctt gccatgaact tttgcctgat
     7981 tccaagattg ggattgtcct caacttgaca ccggcttatc cacgtagcca gcatcctgct
     8041 gatgtcaagg cagctcgtat tgcggccctt tttcaggccc aatctttctt agatccatct
     8101 gtcttgggga cttatccaca ggagttggta gaaatcttgc atgaacacgg tcttttacct
     8161 gatgctacag aggaagagtt ggaactcatt cgtgataata cggtggactt ccttggtgtg
     8221 aactactatc aacctttgcg tgttatggct cctcgatttg ctaagcatcc agagagtcca
     8281 ctcttaccag aacattttta cgagcattat gtgatgcctg gacgtaaaat caattctcac
     8341 cgtggttggg agatttatga gcaagggatt tatgacatcg cccaaaatat caaggaaaat
     8401 tatggcaata ttgagtggat gttgactgag aatggtatgg gtgttgaagg ggaagaaaaa
     8461 ttccgtcaag atggaatgat tcaagatgat taccgtattg actttgtaaa aggtcatctt
     8521 cgtgaacttc accgtgccat tgaagatggt gccaactgta agggctactt gatttggacc
     8581 tttattgact gctggtcatg gctcaacagc tataaaaatc gctatggttt ggtcgaatta
     8641 gacttggaaa cgcaagaacg tcgtctgaag aaatcaggcc actggttcaa agaattaagc
     8701 gataataatg gattttaaaa aggactctga ctgattatcc caatcggtca gagtttttat
     8761 gcttacagga gcttaatttg aactatacca atttttactc ttgacaagtg aaagaaacaa
     8821 gtatatactg tttttactga ttctataaaa gatgaattag actataccaa ttttaaggag
     8881 aaagcacagc ttgcctgtgt cgtatatact atgtgtggaa ttgttggtgt tgttggaaac
     8941 acaaatgcaa ctgatatttt gattcaaggg cttgaaaagc ttgaataccg tggctatgat
     9001 tctgcgggaa tttttgtcct agatggtgct gataaccatt tggtgaaggc ggttggtcgt
     9061 attgcagaat tgtctgccaa gacagctggt gttgagggaa caactggtat cggacatact
     9121 cgttgggcta ctcacggaaa accaactgag gacaatgctc acccacaccg ctctgagaca
     9181 gaacgttttg tcttggtgca taatggggtg attgagaact atcttgaaat caaggaagaa
     9241 taccttgcag gtcaccactt caaggggcag acagatactg aaatagccgt tcatttgatt
     9301 ggaaaatttg cggaagaaga agggctctca gttcttgaag ccttcaaaaa agctcttcat
     9361 attatccgtg gttcatatgc ctttgccttg attgactctg aaaatccaga tgtcatctat
     9421 gtagcgaaaa acaaatctcc acttttgatt ggtcttgggg aaggctacaa tatggtctgc
     9481 tcagatgcta tggctatgat tcgtgaaacc aaccaataca tggaaattca tgaccaagag
     9541 ttggtaatcg tcaaggctga tagcgtggaa gttcaagact atgatggtaa cagtcgtgaa
     9601 cgtgctagct atactgcgga acttgacttg tcagatatcg gtaagggaac ttatccttac
     9661 tacatgctta aggaaattga tgagcaacca actgttatgc gtaaactcat tcaagcctac
     9721 acggatgatg ctggtcaagt agtgattgat cctgctatca ttaaggctgt tcaagacgca
     9781 gaccgcatct acatccttgc agctggaaca tcttaccatg caggatttgc ttctaagaaa
     9841 atgttggaag aattgacaga tacaccagtt gaacttggaa tctcatctga gtggggctac
     9901 ggtatgccac ttctcagcaa gaaaccactc ttcatcttta tcagccaatc tggtgaaaca
     9961 gcggatagtc gtcaagtttt ggtcaaggct aatgaaatgg gaattccaag cttaacagtg
    10021 acaaacgttc caggttcaac cctctcacgt gaagccaact ataccatgct ccttcacgca
    10081 ggtcctgaaa ttgccgtggc atcaactaaa gcctatacag cgcaaatcgc agcccttgcc
    10141 ttccttgcaa aagcagtcgg agaagcaaat ggtaatgcta aagcgcaagc ctttgacctg
    10201 gttcatgaat tgtcaatcgt agctcagtct atcgaatcaa ctctttcaga gaaagaaacc
    10261 attgaagcca aggttcgtga acttcttgaa acaactcgta acgcctttta catcggacgt
    10321 ggtcaagatt actacgtagc catggaagca agtctcaaac tcaaagagat ttcttatatc
    10381 cagtgtgaag gttttgcggc aggagaactc aagcacggaa ccattgcctt gattgaagaa
    10441 ggaacgcctg tcttgtctct cttgtcagat ccagttcttg ccaaccatac tcgtggaaat
    10501 atccaagagg tcgcagcccg tggtgccaaa gtcctcacta tcgcagaaga gaatgtagcc
    10561 aaagataccg acgatatcgt ccttacgacc gtacatccat acctctcacc aatttcaatg
    10621 gtcgtaccaa cgcaattagt cgcttacttt gcaaccctcc accgtggctt cgatgtggac
    10681 aaaccacgta accttgccaa gtcagtaacg gtagaataag ctaaaaaagt ctagttatct
    10741 aggccttttt cttgtgagca aattggttgc ttgtactcaa gattcgtgtt atactcttcg
    10801 aaaatctctt caaaccacgt caacgtcgcc ttgccgtagg tatggttact gacttcgtca
    10861 gttctatcca caacctcaaa acactgtttt gagcagcctg cagctagctt cctagtttgc
    10921 tctttgattt tcattgagta ttagaataat ttttcaaatt gaagtacaga gatagataag
    10981 gagaatcaca atggtagaat tgggaatttc aacatttggg gaaataacgg agcttgaagg
    11041 gactggacaa acttacagtc atgctgaacg cattcgccag ttggtggcag agattgagct
    11101 ggctgacaag gttggtttgg atgtatatgg gattggtgag caccatcggg cggattttgc
    11161 agtatcagcc ccagagattg ttctggccgc tggggcagtc aataccaaga aaatccgttt
    11221 gaccagtgca gtcagcattc tgtcaagcat ggacccgatt cgtttgttcc aacagtatgc
    11281 cactatcgat gctttgtcaa atggacgagc ggagattatg gctggaaggg gctctttcac
    11341 ggaatctttc cctctgtttg gttatgactt gaaagactac gactctcttt ttgatgagaa
    11401 attagccttg cttcagttag tcaatgaaaa gaccaagtta gactggcaag gtcgattgac
    11461 tcaaacgatt gctggtaaag aagtttatcc tcgtccagtt caggacaaat tgcccttgtg
    11521 gatagctaca ggtggtcatg tcgaatcaac agtgaagatt gctcaggctg gtctaccgat
    11581 tgtatatgct attattggtg gtaatccacg ttattttaaa aagttgattc aggcttatcg
    11641 tgagattgga agcgaagcgg gtcatgctga caaagacttg aaagtgggag cccattcttg
    11701 ggggtggatt gcggaagatg gtgagcaggc ggtgaaagat tatttccatc cgactaagca
    11761 agtggtggat gctatttcca aagaccgtcc gcactggcag gaattgcgtt atgagcaata
    11821 tttggagcag gtagggccaa atggcgccat gtttgttggc aatccagatc aggtggccga
    11881 aaaattgatt cgcatgatag aggatttagg attggaccgc ttcatgcttc atctaccgct
    11941 tggttctatg cctcatgacc aggttctgag agctattgaa ctcttcggaa cacaagttgc
    12001 acccaaagta cgagcttatt ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt
    12061 tattaggaca acaaatattg tacgaaaatt aatcccccga gctataatgc ttgggggatt
    12121 tttctatagg agggctagtt tagttctctt ttttattttt tagtaagaaa ccgagaccaa
    12181 ggagcgcaag gaggctgatt cctgcaaata ggagtttgtt ttcgtttttg attcctgtat
    12241 ttggaagttc agcttgtcta tctggggttg caggtatatt tttcttgcta gagttttcta
    12301 ccgattcgtt ttgaaccgct tcttttacag atgatgcttg tgcttcttgt gctggttgtt
    12361 cagcttgtga atcagctgta gcttggctag gtttattttc cgcatcagct actttggcat
    12421 ctggtttagt agaatcaggt ctagcttctg gagctgggtc ttgatgttca ggcttggaag
    12481 gggttgagtc tggtttctct tctgcagttg actcatggct agttccattt tgagagactc
    12541 gaagaacagt agctgtaagg gcattcaatt tcaagccttt ttcagtccat tcaagtcctt
    12601 tcgggttggc aattccgact ggtcctgctt ggttttcatc tgccaaaact tccgcatttc
    12661 ttagatgtgc aaaggcagtt cccaaattaa attcgcgagc tttttcatcc gcattgacaa
    12721 agactgcgta gatatcgccg tttggagcag tgatttggta gccaatcact acatcctctt
    12781 tttccacacc attttggcct gggacagtga tgaggtggac acggtctttg atatcttgga
    12841 gactcttaag tcggaaggca tctgtagatt gacgaagggc aatcaaacct ttcatatagt
    12901 cacggctctt gacattttca ggataagctt taccatctgt agccttagtc cagtcaaact
    12961 tgttgactgc gtcgctagaa tcgtaagaat catggatgaa gtaaggatag tcaaatgggt
    13021 tgccgtcctt atcacgcaac aagtgagatt tgtttggaac cttatcctct gctactggag
    13081 tcttgtaggc tgggtcacgg aattgtttag tacgtccata ttcctgaccg gagtggataa
    13141 atggagttcc ttgagctgtc aagaccatga gatttccaag tcgtaaacga cggtggattt
    13201 cagcatagtt ctcagccttg cttgggtctt ttttgataga ctgggcaatg atgtcaaaga
    13261 gggtcaagtt atcatgggct gcgatgtatt ggatgacatc tccagggctg tcagcttcaa
    13321 agttagttgg ttgagcaatg agatttttaa agatggtgtt gacatcacgc ttgccacctg
    13381 tgataaaggc aggttgacct tcgtttggat aaccagattt gaggttgtta cggatgtcat
    13441 ctgaaaagac agcgacagta tcggtatgtt tcatccaatc ttggtcagca gctttagtag
    13501 gcatgttttc atcaccggca taggttctcc aaccttcgcc taacatgatt agatttggat
    13561 tgagggcgcg tgcagccttg taagcttctt cgatagaagc ggcgtcatgg tctcccatca
    13621 tatcgaagcg gaagccatcc actttgtagg tatcaactag gtatttgata gagtcaacta
    13681 ggaggcgttt ggtcatatgg tgggttgtcc ccaagcgtcc accaccaaag ctagttcgag
    13741 gtgtgccatc ggcatccata aagtggtagt agtttggctc taggtcttca aagatatcga
    13801 ctttggctgt gtggttataa acgacatcta ggatagctcc cataccacgt ttgtggattt
    13861 cgttgatgag gtttttaaat tctgcgattc gtttttctgg attcttagga tcgcttgagt
    13921 acataccagt caaggagaag tagttttgag ggtcatatcc ccagttgtag ttgctgttgc
    13981 ttgaagcata gtcagacaag cgttcatggt ttttcaattc attgacaaag tagtaagaca
    14041 agactggaag gagctggata tgggttacac ccaagtcttt gagatagtct agtttttcaa
    14101 tgaaggcttc aaaagtccca aatggtttgg tcaagtcttt tgcaatggca ggatctgaag
    14161 tgaagtcacg cacatgagct tcgtagataa cggcgtcttc acgagtcttg aaattgtgaa
    14221 tcttaccata agtcaagtct tgaggtccga gtttagctgg atctacaaag gcggctttag
    14281 ccactttatg ggcatcgtca atcttggcat cgttgctatt ccaagcagca agagatttag
    14341 cgtaaggatc gagtgcaaga acagttttac cttgacgctc gatttggtat tgataatagt
    14401 agccagtgaa atctgtgatt ccgagtttgt ttgtgctgtc tagagtttgt ttccaagttc
    14461 ctctttcccc tttttcgaga gcgacagttc caactacttt gtcagggtca ttcttgtcgt
    14521 agacaacaac agaaacctta tcagcacttg gtgaccaaag ggtcaaatca acttgttttc
    14581 cttcttcttt taggtcagct cccagtttgc catcatagct gtatgtctca tctttcaggc
    14641 gccagcttgt tttggtagtg aattggtcgg aattgtagct aacagtataa ggatgttttg
    14701 tgtcagagaa atctccgctg taggtcactt tcttaccagc ttcatcgatt gcaacatcgg
    14761 taatagttac cttgtttcct aggtgattag tgatgttgga gtgtttgagg atatcttctt
    14821 ttttagcacc gacaagtgtt gaaaagctac tttcaatgct agaagtgcct acgtgttggg
    14881 ctcctgtcat acggatatca tggacatagt atggatttgt gtaaatcgat tcatcatcgt
    14941 cttttaggaa aatttggcta tgatttttca aatctgtgaa cttataattt tctttacgga
    15001 ttttcacgtc gtctccttgt ttgctctcat ctagtaataa aaatccaaat tctcttgcgg
    15061 cttcattaag aggaatgtcg atatagcggc catatttgcc tgtagccgta aagtctgttc
    15121 cgtcaggcca ttgagcgcta cttggatttt tcacatctcc ccagtaccag agagatttct
    15181 tgtcatagtt gccatctgtg cggtagtagt tgacgcgaac agttcctgca ggctgtggct
    15241 cgtaagagaa aaccttgtaa tcttggtcta accaagcttc gttcattttt ggaactagtt
    15301 tttctacaga tttatcgccg gttagatttt ttccagctgt attgttgatg aggaagctaa
    15361 ttttcttggc ttgttctccc tttaatttga catctaggta atagccgtag tcatctttct
    15421 tggcatcctt gaaggacaaa gctccgtttg gccagttttc agatggtttt tcaacatcgt
    15481 cccaagtcca tagtccttga gcatccttgt tttcttcagg aagttttttg acatggatac
    15541 ggaagtagtt atcttcgatg ggctcttctg ccttagtttc agttgttact ggactagtag
    15601 aagtagttgg ctcacttgaa cgatcttgtc cagtttgtgg tgctggatcg gctgggcttg
    15661 cagcaggagt tgttggctct gttgcaggtt tttcttctgt tttctctagg gaagcgtttg
    15721 catttccaag tgaagaaata tcacttttgt tcttaccaga gccagctgct gtatcagtaa
    15781 gaggttgggc aagggtggtt gtatttctgt tgttgggttc gttagtggtt ggtgtacttt
    15841 cgtcggatga gatagttggt gtagccatgg caagcaagac aaggcttgcg ccgataagga
    15901 cagaaccagt cccatttttg agggaacgga tgctgtagac catttttttc tcagtgtgag
    15961 atggtgtttt tctcataatg attctccaat caataaattt ctatatcagt atagcatgta
    16021 gtaaaacaat atgcaagcgt tttctttgat ttgtgaaaaa aattcttact tttgagaagt
    16081 tttctgtact attttatata tcagtataaa tgacggagat aaaaatgtca cataagccaa
    16141 gccgtattat taggaagatg atgtgttccc agctattttt attcagaaat tgatctctaa
    16201 cattaccaat aaaaaagaaa aatatcttga caaacaaggg aaaattttgt tacaataata
    16261 gacggtactt tttacttttg gtctctcaag agtgtacagg gacgtgctga caaatgttgc
    16321 aaaagtacac acagatgata tctgtcacca agtgtatcat caccaaaaat aaaaaaacac
    16381 aggagaatgt agatgcctac aattaaccaa ttggttcgca aaccgcgtaa atcaaaagta
    16441 gaaaaatcta aatcaccagc tttgaacgtt ggttacaata gtcataaaaa agttcaaaca
    16501 aacgtttctt caccacaaaa acgtggtgtt gcaactcgtg ttggaacaat gacacctaaa
    16561 aaacctaact cagcccttcg taaattcgct cgtgtacgtt tgagcaacct tatcgaagtt
    16621 actgcctaca tcccaggtat cggacacaac ttgcaagagc acagcgtggt gcttcttcgc
    16681 ggtggacgtg taaaagacct tccaggggta cgttaccata tcgtccgtgg tgcacttgat
    16741 actgcaggtg ttaacgatcg taaacaaggt cgttctaaat acggtactaa acgtccaaaa
    16801 gcataaggaa aggggataaa gagaaatgag tcgtaaaaat agagctccaa aacgtgacgt
    16861 attgccagat ccgctataca attcacaact agttactcgt cttatcaacc gcgttatgct
    16921 tgatggtaaa cgtggtactg ctgcttcaat cgtttacggt gcttttgagc aaatcaaaga
    16981 agctactggc aacgatgcac ttgaagtatt tgaaacagct atggaaaaca tcatgcctgt
    17041 acttgaagta cgtgcacgtc gtgttggtgg ttctaactac caagtcccag ttgaagttcg
    17101 tccagaacgt cgtacaacac ttggacttcg ttggttggta acaatcgctc gtcttcgtgg
    17161 tgaacacaca atgcaagacc gtcttgcaaa agaaatcttg gatgctgcta acaacactgg
    17221 tgcagctgtt aagaaacgtg aagatactca ccgtatggct gaagctaacc gtgcattcgc
    17281 acacttccgt tggtaagata ggatgcgaaa gcgttaagaa agtcccagag aaaataggga
    17341 atcgaagcag gttgcggttg caaccaatga gattcatctt tttctccaga cttttagctt
    17401 gagctcaact aaatcatgat gctaggcacg gtaaggatgc aaggtgaaaa taggaaactg
    17461 acgcagtatt caacgaatac aaggagtttt atctttttca cgcagcatcc cgttccagct
    17521 cacatcggct aactaacttt agcccgggtt caaattagct aaatcgatta gtattagcta
    17581 taactcagct taccatctcg taagttgaaa ccaacaatag catgaaaaca ttgagaacgg
    17641 gtaggtcctg cctatccgtt tttattaaaa tcgtgttata atagaataga aatcaaaaat
    17701 aaataggaga aacaaacctc atggcacgcg aattttcact tgaaaaaact cgtaatatcg
    17761 gtatcatggc tcacgtcgat gccggtaaaa caacaactac tgagcgtatt ctttactaca
    17821 ctggtaaaat ccacaaaatc ggtgaaactc acgaaggtgc gtcacaaatg gactggatgg
    17881 agcaagagca agaacgtggt atcacgatca catctgctgc gacaacagct caatggaaca
    17941 accaccgcgt aaacatcatc gacacaccag gacacgtgga cttcacaatc gaagtacaac
    18001 gttctcttcg tgtattggat ggtgcggtta ccgttcttga ctcacaatca ggtgttgaac
    18061 ctcaaactga aacagtttgg cgtcaagcaa ctgagtacgg agttccacgt atcgtatttg
    18121 ccaacaaaat ggacaaaatc ggtgctgact tcctttactc tgtaagcaca cttcacgatc
    18181 gtcttcaagc aaatgcacac ccaatccaat tgccaatcgg ttctgaagat gacttccgtg
    18241 gtatcattga cttgatcaag atgaaagctg aaatctatac taacgacctt ggtacggata
    18301 tccttgaaga agacatccca gctgaatacc ttgaccaagc tcaagaatac cgtgaaaaat
    18361 tgattgaagc agttgctgaa actgacgaag aattgatgat gaaatacctc gaaggtgaag
    18421 aaatcactaa cgaagaattg aaagctggta tccgtaaagc gactatcaac gttgaattct
    18481 tcccagtatt gtgtggttca gccttcaaaa acaaaggtgt tcaattgatg cttgatgcgg
    18541 ttatcgacta ccttccaagt ccacttgaca tcccagcaat caaaggtatt aacccagata
    18601 cagacgctga agaaactcgt ccagcatctg acgaagagcc atttgcagct cttgccttca
    18661 agatcatgac tgacccattc gtaggtcgtt tgacattctt ccgtgtttac tcaggtgttc
    18721 ttcaatcagg ttcatacgta ttgaatactt ctaaaggtaa acgtgaacgt atcggacgta
    18781 tccttcaaat gcacgctaac agccgtcaag aaatcgacac tgtttactca ggtgatatcg
    18841 ctgctgccgt tggtttgaaa gatactacaa ctggtgactc attgacagat gaaaaatcta
    18901 aaatcatcct tgagtcaatc aacgttccag aaccagttat ccaattgatg gttgagccaa
    18961 aatctaaagc tgaccaagac aagatgggta tcgcccttca aaaattggct gaagaagatc
    19021 caacattccg cgttgaaaca aacgttgaaa ctggtgaaac agttatctca ggtatgggtg
    19081 aacttcacct tgacgtcctt gttgatcgta tgcgtcgtga gttcaaagtt gaagcgaacg
    19141 taggtgcgcc tcaagtatct taccgtgaaa cattccgcgc ttctactcaa gcacgtggat
    19201 tcttcaaacg tcagtctggt ggtaaaggtc aattcggtga tgtgtggatt gaatttactc
    19261 caaacgaaga aggtaaagga ttcgaattcg aaaacgcaat cgtcggtggt gtggttcctc
    19321 gtgaatttat cccagcggtt gaaaaaggtt tggtagaatc tatggctaac ggtgttcttg
    19381 caggttaccc aatggttgac gttaaagcta agctttatga tggttcatat cacgatgtcg
    19441 actcatctga aactgccttc aagattgcgg cttcactttc ccttaaagaa gctgctaaat
    19501 cagcacaacc agctatcctt gaaccaatga tgcttgtaac aatcactgtt ccagaagaaa
    19561 accttggtga tgttatgggt cacgtaactg ctcgtcgtgg acgtgtagat ggtatggaag
    19621 cacacggtaa cagccaaatc gttcgtgctt acgttccact tgctgaaatg ttcggttacg
    19681 caacagttct tcgttctgca tctcaaggac gtggtacatt catgatggta tttgaccact
    19741 acgaagatgt acctaagtca gtacaagaag aaattattaa gaaaaataaa ggtgaagact
    19801 aatccgtcct cactctagaa ggaagtcact tagtggcttc cttttgtctt tagaaaatac
    19861 ctctaaatat ggtaaaatag tagaagaata atgtgaggaa aatgaatgtc aaatagtttt
    19921 gaaattttga tgaatcaatt ggggatgcct gctgaaatga gacaggctcc tgctttagca
    19981 caggccaata ttgagcgagt tgtggttcat aaaattagta aggtatggga gtttcatttc
    20041 gtattttcta atattttacc gattgaaatc tttttagaat taaagaaagg tttgagcgaa
    20101 gaattttcta agacaggcaa taaagctgtt tttgaaatta aggctcggtc tcaagaattt
    20161 tcaaatcagc tcttgcagtc ctactatagg gaggttttct ctgaaggtcc atgtgctagt
    20221 caaggtttta agtcccttta tcaaaatttg caagttcgtg ctgagggtaa tcagctattt
    20281 attgaaggat ctgaagcgat tgataaggaa cattttaaga agaatcatct tcctaattta
    20341 gccaaacaac ttgaaaagtt tggttttcca acttttaact gtcaagtcga gaagaatgat
    20401 gtcttgaccc aagagcagga agaggccttt catgctgaaa atgagcagat tgttcaagct
    20461 gccaatgagg aagcgctccg tgctatggaa caactggagc agatggcacc tcctccagcg
    20521 gaagagaaac cagtctttga ttttcaagcg aaaaaagctg cagctaaacc caagctggat
    20581 aaggcggaga ttactcctat gatcgaagtg acgacagagg aaaatcgtct ggtatttgaa
    20641 ggggttgttt ttgatgtgga gcaaaaagtg actagaacag gtcgtgtttt aatcaacttt
    20701 aaaatgacgg actatacttc aagtttttct atgcaaaagt gggttaaaaa cgaggaagag
    20761 gcccagaagt ttgacctcat caagaagaat tcttggctcc gagttcgagg gaatgtggag
    20821 atgaataatt tcacacgcga tttgactatg aacgtacagg atctgcagga agttgttcac
    20881 tatgagcgga aggatttgat gccagaaggt gagcgtcggg ttgagtttca tgctcatact
    20941 aacatgtcga ctatggatgc tttgccagag gtcgaagaga ttgttgcaac agctgctaag
    21001 tggggacaca aggcggttgc tatcacggac catgggaatg tccagtcctt tccacatggc
    21061 tataaggcgg ctaagaaagc gggaatccag ctgatctatg gaatggaagc caatatcgtg
    21121 gaggaccgtg tccctatcgt ctataacgaa gtggagatgg acttgtcaga agcaacctac
    21181 gtggtctttg acgtggaaac gacgggactt tcagctatct ataatgactt gattcaggtt
    21241 gcggcctcta agatgtacaa ggggaatgtt attgctgaat ttgatgaatt tatcaatcct
    21301 gggcatccct tgtcagcttt tactacagag ttaactggaa ttacagatga tcatgtcaaa
    21361 aatgccaaac cactagaaca agttttgcaa gaattccaag aattttgcaa ggatacggtc
    21421 ctagttgccc acaatgctac ctttgacgtt ggctttatga atgctaatta tgagcgtcat
    21481 ggtcttccaa agattagtca gccagttatt gatacgctgg agtttgctag aaacctctat
    21541 cctgagtata aacgccatgg tttggggcct ttgaccaagc gttttggtgt ggccttggaa
    21601 catcatcaca tggccaacta cgatgcggaa gcgactggtc gtctgctttt catctttatc
    21661 aaagaggtag cagaaaaaca tggtgtgacc gatttagcta gactcaacat tgatctaatc
    21721 agtccagatt cttacaaaaa agctcggatc aagcatgcga ccatctatgt caagaatcag
    21781 gtaggtctaa aaaatatctt taagctggtt tccttgtcta ataccaagta ttttgaagga
    21841 gtgccacgga ttccgagaac ggttctagat gcccatcgag agggcttgat tttaggttca
    21901 gcctgttcag agggtgaagt ttttgacgtg gtcgtttctc aaggtgtgga tgcggcggtt
    21961 gaggtggcca agtattatga ctttatcgag gtcatgccac cggctatcta tgcgcccttg
    22021 attgccaaag agcaggtcaa ggatatggag gaactccaga ccattatcaa gagtttgata
    22081 gaggttggag atcgccttgg caagcctgtt ctggctacgg gaaatgttca ctatatcgaa
    22141 ccggaagaag agatttatcg tgaaattatc gtccgtagtt tgggacaggg tgcgatgatt
    22201 aaccgaacta tcggtcatgg tgaacatgcc caaccagcac cacttccaaa ggctcatttt
    22261 cgaacgacta atgagatgtt ggatgaattt gcctttttgg gagaggaact ggctcgtaaa
    22321 ctggttattg aaaacaccaa tgccttggca gaaatatttg aacccgttga agtcgttaag
    22381 ggtgacttgt atacgccttt catcgacaag gctgaagaaa cagttgctga gttgacctat
    22441 aagaaagctt ttgagattta tggaaatccg ctgccagata ttgttgattt gcggattgaa
    22501 aaagaattaa catccatact ggggaatgga tttgctgtga tttatctggc atcgcagatg
    22561 ctggtgcaac gttctaatga acggggttat ttggttggtt ctcgtgggtc tgtcggatct
    22621 agtttcgttg cgaccatgat tgggattacg gaagtcaatc ctctctctcc tcactatgtc
    22681 tgtggtcagt gtcagtacag tgagtttatc acagatggtt cgtacggttc aggatttgat
    22741 atgccccata aggactgtcc aaactgtggt cacaaactca gtaaaaacgg acaggatatt
    22801 ccgtttgaga ccttccttgg ttttgatggg gataaggttc ctgatattga cttgaacttc
    22861 tcgggagaag atcagcctag cgcccacttg gatgtgcgtg atatctttgg tgaagaatat
    22921 gccttccgtg cgggaacggt tggtacggta gctgccaaga ctgcctatgg atttgtcaag
    22981 ggttacgagc gagattatgg taagttttat cgtgatgcag aagtagaacg cctcgctcaa
    23041 ggagcggcgg gtgtcaagcg gacaacaggc caacacccgg ggggaatcgt tgttattccg
    23101 aactacatgg atgtctacga ttttacgcct gtccagtatc cagcagatga tgtcacggct
    23161 gaatggcaga ccactcactt taacttccac gatatcgatg agaacgtcct caaactcgat
    23221 gtactgggac atgatgatcc gaccatgatt cgaaaacttc aggatttgtc tggtattgac
    23281 cctaataaaa ttcctatgga tgacgaaggc gtgatggcac tcttttctgg gactgatgtg
    23341 ctaggggtaa cacctgaaca aattggaacg cctacgggta tgttggggat tccagagttt
    23401 ggaacaaatt tcgtacgtgg aatggtagac gaaacccatc cgacaacctt tgcggaattg
    23461 cttcagctgt ctggtctgtc ccacggtact gacgtttggt tggggaatgc tcaggatctg
    23521 attaagcaag gaatagcgga cctatcgact gttatcggtt gtcgggacga catcatggtt
    23581 tacctcatgc atgcgggtct ggaacctaag atggccttta ccattatgga acgggtacgt
    23641 aagggtttgt ggctaaagat ttcagaagag gagagaaatg gctatatcga agcaatgaag
    23701 gctaataagg tgccagagtg gtatatcgaa tcctgtggga aaattaagta catgttccct
    23761 aaggcccatg cggcagccta cgttatgatg gccttgcgtg tagcttactt caaggttcac
    23821 catcctattt attactactg tgcttacttc tccattcgtg ctaaggcttt tgatatcaag
    23881 accatgggtg cgggcttgga ggtcatcaag cgcagaatgg aagaaatctc tgaaaaacgg
    23941 aagaacaatg aagcctctaa tgtggaaatc gatctctata caactcttga gattgtcaat
    24001 gagatgtggg aacgaggttt caagtttggt aaattagatc tctactgtag tcaggcgaca
    24061 gagttcctca tcgacgggga tacccttatc ccaccatttg tagcaatgga tggtctggga
    24121 gagaacgttg ccaagcaact ggtgcgggcg cgtgaagagg gagaatttct ctctaaaaca
    24181 gaactacgca agcgtggtgg actctcatca accttggttg aaaagatgga tgagatgggt
    24241 attcttggaa atatgccaga ggataaccag ttgagtttgt ttgatgagtt gttttaaaaa
    24301 attgcttaat aatctattaa aagaggctaa cgtatatcca atagatttac attagctttc
    24361 ttttttgtta aaatagtcta tggaaagagg gtgagagtat gtcaaagatg agtataagca
    24421 tccgtctgga tagtgaggtt aaggagcagg cccaacaggt gtttagtaat ctgggaatgg
    24481 atatgacaac agctattaat attttccttc gtcaggcaat tcaatatcag ggactacctt
    24541 ttgatgttag actagacgaa aatcggaagt tgctccaagc gttaacggat ttagaccaaa
    24601 atcgtaatat gagccagtct tttgaatcag tctcagattt gatggaggac ttacgtgctt
    24661 aagattcgtt atcataaaca gtttaaaaaa gattttaagt tggctatgaa gcgtggtttg
    24721 aaggcagaat tattagaaga agttttgaat tttctggttc aagaaaaaga acatcctgcc
    24781 agatatcgtg atcattcatt gacggcatcc aagcattttc aaggagttcg tgaatgccat
    24841 acccagccag attggctttt ggtttataaa gtagacaagt cggaattgat tttaaatttg
    24901 ctgaggacag gcagtcacag tgatttattt taatctattt taagggggtt ctcatgaaac
    24961 taagaatatt tgcggaagat aagccggcta agaaggtatt tgaatatcaa ttagaacttg
    25021 ctgatcgtac aattcttcta tcgacagcac tcttgtcagg tgctattgct ttagcaggaa
    25081 tcttttctgc tttgagagaa aaataaaaat agaaaagaga aaacagaatg gttttaccaa
    25141 attttaaaga aaatctagaa aaatatgcga aattgttggt tgcgaacgga attaacgtgc
    25201 aacctggtca cactttggct ctctctattg atgtggagca acgtgaattg gcacatctaa
    25261 tcgtgaaaga agcttatgcc ttgggtgcgc atgaggtcat cgttcagtgg acagatgatg
    25321 tgattaaccg tgagaaattc ctccatgccc cgatggagcg tttggacaat gtgccagaat
    25381 acaagattgc tgagatgaac tatctcttgg agaataaggc tagccgtctt ggagttcgtt
    25441 catctgatcc aggtgccttg aacggagtgg acgctgacaa gctttcagct tctgctaaag
    25501 ctatgggact tgccatgaag cctatgcgta tcgcaactca atctaacaag gttagctgga
    25561 ctgtagcagc tgcagcagga cttgagtggg ctaagaaagt cttcccaaat gctgcgagcg
    25621 acgaagaagc agttgatttc ctttgggacc aaattttcaa aacttgccgt gtctacgaag
    25681 cagatcctgt taaggcctgg gaagagcatg cagctatctt gaagagcaag gccgatatgc
    25741 ttaataagga gcaattttca gcccttcact acacagcgcc aggaacagat ttaacacttg
    25801 gtttgccaaa gaaccatgtt tgggaatcag ctggtgctgt caatgcacag ggcgaaggat
    25861 tcttgccaaa tatgccgaca gaagaggtct tcacagcacc tgacttccgt cgtgcagatg
    25921 gttatgtcac ttctacaaaa ccgcttagct acaacggaaa tattattgaa ggcattaagg
    25981 tgacctttaa ggatggacaa atcgtagata tcactgctga gaagggtgat caggttatga
    26041 aagaccttgt ctttgaaaat gcgggtgcgc gtgccttggg tgaatgtgcc ttggtaccag
    26101 atccaagtcc aatttctcag tcaggcatta ccttctttaa cacccttttc gatgaaaatg
    26161 cgtcaaacca cttggctatc ggtgcagcct atgcgactag cgttgttgat ggagcggaga
    26221 tgagcgaaga ggagcttgaa gctgcagggc ttaaccgttc agatgttcac gtagacttta
    26281 tgattggttc taaccaaatg gatatcgatg gtattcgtga ggatggaacg cgggtacctc
    26341 ttttccgtaa tgggaattgg gcaaattaag gagataatat gttaggaagt atgttcgttg
    26401 gtctcctagt gggattttta gcaggtgcta tgaccaatcg tggagagcga atgggatgtt
    26461 ttggaaaaat gtttctcggt tggatcggag cctttctagg tcacttgctc tttggaactt
    26521 gggggccagt tttatcagga acagctatta tcccagctgt tttaggtgcc atgattgtct
    26581 tagctatttt ttggagacga ggaagttaat ttcctaaatc tgatactcaa tgaaaatcaa
    26641 agagcaaact aggaaactag ccgcaggttg ctcaaagcac tgctttgagg ttgcagatag
    26701 aactgacgaa gtcagtaaca tatatgcggc aaggcgacgt tgacgcggtt tgaagagatt
    26761 tttgaagagt atgaaacgaa aaggaggttg gtcattgtac tagcctcctt ttgatatgat
    26821 ataatagttc tatgagatta gataaatttt tagttgcctg tgcggtggga agtcggactg
    26881 aggtcaaaaa cttgctcaag gctgggcgcg tgactgtaaa tggtaaaaaa gaaaaatcag
    26941 ctaaattgca gattgatgaa aaaatagatg agattcgctt tgatgggcaa gtgttggagt
    27001 atgaagagtt tgtctactac atgatgaaca agcccaaagg agttatctca gcgactgagg
    27061 atcccaagca cagaaccgtt ctggacttgt tggatgactt ggcgcggagt aaggaagttt
    27121 ttccagtagg acgcttggat attgacacgc atggtctttt gctcttgacc aataatggtc
    27181 agctggctca tgttcttctt tctcccaagc gtcatgtgga caagacttat caggctcagg
    27241 tcaagggaat tatgacccaa gaagatgtgg agacatttat caagggcatt ccgctcaaag
    27301 actttacctg tcagcccgct agactggaga ttctttccac agatgcagaa aagaatcaga
    27361 gccaaatccg tgtgaccatt gcagaaggga agtttcatca gatcaagcgt atggtgggct
    27421 actgtggcaa ggaagtggtg gacttgcaac gattgactat gggaacttta gtattagatg
    27481 agaacctgga acgaggggaa tggcgtcgct tgaccaagga agaattagaa attctccgcg
    27541 ctaatattat ttaatttagt ttaatactca atgaaaatca aagagcaaac taggaaacta
    27601 gccgcaggct gtacttgagt acggcaaggc gacgttgacg tggtttgaag agattttcga
    27661 agagtataaa ttcgaaaaag gtgagggaga atgtccttac cttttatgtt ttttagttgc
    27721 ttcctttgtg aaaagagtta taatagactg tagaataaaa ggaggaatct atgaacgcga
    27781 ttcaagaatc atttactgat aaactatttg ccaactatga agcaaatgta aaataccaag
    27841 cgattgaaaa tgctgccagc cacaacggaa tttttgcagc tctggaacgt cgccaaagcc
    27901 atgtagacaa cacacctgtt ttctcattgg atttaaccaa ggacaaggtc actaaccaga
    27961 aagcgtctgg tcgttgctgg atgtttgcgg ctctcaacac cttccgccac aaactcatct
    28021 cgcaatacaa attggagaac tttgagttgt cacaagccca cactttcttc tgggataagt
    28081 atgagaaatc aaactggttc ttggagcaag tcattgcgac ttcagaccaa gaattgacta
    28141 gccgcaaggt tagcttctta ctccaaacac ctcaacaaga tggtggtcaa tgggatatgg
    28201 tcgtttccct ctttgaaaaa tacggtgtcg tgcctaagtc agtttatcct gagtctgttt
    28261 catctagcag cagtcgtgag ctaaatgcga tccttaataa attgcttcgt caagatgctc
    28321 aaatcttgcg tgatttgctt gtttctggtg cagatcaagt gactgttcaa actaagaaag
    28381 aagacctctt gcaagaaatc tttaactttc ttgctatgtc attaggactt ccaccacgca
    28441 agtttgactt tgcttatcgc gataaagata acaactacaa aagtgaaaaa ggaatcacac
    28501 cacaagagtt ctacaagaaa tatgtcaatc ttcctttaga agactacgtt tctgttatca
    28561 atgctccaac tgctgataaa ccttacggaa aatcttacac agttgagatg ttggggaatg
    28621 tggttggtag ccgtgcagtt cgctacatca acgttccaat ggagcgcttg aaagaattgg
    28681 cgattgccca aatgcaagca ggtgagactg tttggtttgg ttctgatgtc ggccagctca
    28741 gcaaccgtaa ggctggcatc cttgcgacag atgtttatga ctttgaatca agcatggaca
    28801 ttaaacttac tcaagacaag gctggacgtt tggactatag tgaaagcttg atgacccacg
    28861 ccatggtctt gacaggtgtt gacttggacg aaaatggtaa atcaaccaag tggaaggttg
    28921 aaaactcatg gggagacaag gtcggtacag atggttactt tgttgcctca gacgcttgga
    28981 tggacgaata cacataccaa atcgttgttc gtaaggaatt gctgacagca gaagaacaag
    29041 ctgcctatgg agcagaacca atcgtacttg caccatggga tccaatggga gccttggctg
    29101 aataaaagca tagaaaaaag gaatcagatt ttagaacctg gttccttttt agttgcttga
    29161 ttacatgatg tgaagaacat gtgccacaat acccactgcg aagagggcaa ggataatagt
    29221 gattggagat acttttttct taagtaagta catgcaaagt aaagtaagga gtagtcctga
    29281 taatccagga atcaacatat ccaagttttg ttggaaagta gtaacttttt caggagtttg
    29341 agacaatcct tgtcctactt gtgcgaatgc ttcttggata cctttagacc cttctggcaa
    29401 tttatcccaa tggatataag ccttttcatc tagttgaact ttagaaacat cgaaagcaaa
    29461 tttaatattt acccagcgtt gaacaaggac agcaagaatg aacatcccaa ggatagaagc
    29521 tcctttagtg atatcttgaa ggataccacc agacatatct ttagtgattt ctgatccagc
    29581 cttgtatcca atctcttgaa cataccacaa gaatgacata cgaatcaagt tccatgcaac
    29641 aaagaagagg agtggaccca agatattgcc agtaagggca agtgaagcac cgagagatcc
    29701 aaggattggg cgtactgtaa accagaatac tgggtcaccg ataccagcaa gaggtcccat
    29761 cataccgatt ttaacccctt ggatagcagc gtcatcgatt tccacaccgt tagcacgttc
    29821 ttcttcaagc gcaagagtaa cccccatgac tggagcagct acgtatggat gagtgttgaa
    29881 gaactcaagg tgacgctcaa gagcagcgat ttgatcttct tttttagtat agagtttttt
    29941 gatagctgga atgagtgtat aagcccagcc caagttttgc atccgttcaa agttccaaga
    30001 cccttgtaag aaggttgaac gccaccaaac ttttttacga tctgatttag ttaattgaag
    30061 tttttcagtc atgatgtttt cagtcctttc ttatcttagt agtcttctag gatatcgccg
    30121 attgggtcgt tagaagttgc ggctcctccg ccaccatttc caccagtttt agaaaggtga
    30181 aggtagataa gagcgatagc aacaccgata gcaccgaatc cgattagagt aatatctgac
    30241 acagcagcga gaacgaaacc aagagcgaag aatggccata cttcacgagt tgccatcatg
    30301 ttgataacca tggcgtaacc aacggcaacg accataccac caccgatagc cataccatct
    30361 ttgagccagt ctggcatggc actaaggata ctttgtacag tttcagttgg taccataagg
    30421 agaagagctg caggaagcgc gatacgaagt ccttggaaaa gtagcgcaat gaaatgcgca
    30481 cgctccacag cgccgaagtc acctttttta gcggcagcat ctgcagtatg aaccaaacca
    30541 actgaaattg tacgaacaat cattgtcaag aaaagtccag ctacggcaag agggatagca
    30601 accgcttggg caacaccgat accagtcttg gtaaagtcac caccaagaac catgataatg
    30661 gcagcagcga cagaagcaag tgcagcatca ggagcgatag cagcaccgat atttgaccaa
    30721 ccaagggcaa tcatttgaag cgatccaccg aggataatcc ctgcttccaa gtgacctgtt
    30781 acaagcccaa taagggtaca ggctacaagt ggttggtgaa attggaactg gtcgaggatg
    30841 ccttcaagac ctgcaaagaa ggctacaacg actactaaaa ccatagaaat aatagacatg
    30901 tttaaaatcc tttcataaat aatggcttat ttgacattgg ctttgttaat caagtcaaac
    30961 aaatcttttt tagaatcatt tggtacttta cggacatcaa attcaacacc caagtcacgc
    31021 attttttcaa atgtagcaac atcttctttg tccatagaca aaacggtatt gaccaatgtt
    31081 ttacctgttg agtgagccat agaaccaacg ttaagagtct tgattggcac gccgccttcg
    31141 atggcacgaa gggcatcttg aggtgtttca aacaagataa gggcatgtgt ttctccaaaa
    31201 cgtgggtctt ttgaaatctc aatcagtttt tgaattggaa ccacgttagc cttgacatta
    31261 cctggagctg cttgtttaat caattcttta cgaaggtcgt ctttagccac gttatctgaa
    31321 gcaacgatga tacgatttgc ttttgaatct ggagtccaag cagttgcaac ctgaccgtga
    31381 agtagacgtg tgtcaagacg ggcaagattg attttcaatt taccgtctcc gataacagtt
    31441 ccttctggga tagcagtttg ggcaactgga gcagctgcag cgcttgcaac ttcttcaact
    31501 ggatttagct cttctggaag agctttgatg ccatctttgg cttctttaat gatattagca
    31561 gcgacttttt ctacacctgc agcagcgtcc atgaggcgct ctgtgtaggc ttgaatcaac
    31621 atcggtaagt taagtcctgt gatgatggca aacttacgct caggattttc tcccatcacg
    31681 cgactagctt ggttaaatgg agaaccactc caaaggtcag ccaaaactag aacctcatct
    31741 tctgcgtcaa atgcagcaac agcgttatta aacttagcgt atagatcatc aggaccttca
    31801 tttggcataa aggtcacaac ttgaaccttt tcttgttcac caaagatcat agatcctgac
    31861 tgatgaatac ccgcagcaaa ttcgccgtgg ctcgcaataa tgattccgat actcattatt
    31921 gtcattcctc cttttttgtt ttagttttca tttaagaaaa ctttaagact gtttaagtat
    31981 aaaccgtttt cataaaaaaa gcaactattt atcataaaaa attaaaaaat ttttattttt
    32041 atatgttgat atgttgagtt tttgaggagt aatcttgaat tcttatttaa aatttaatat
    32101 aaaaaagttg gaagaagctt ccaactttta aaataggttt ctattagatt agtgggtgaa
    32161 gtcgagtacc atacgtcctt ggatttggcc tttttccatt tcgtcgaaaa tggcaacagc
    32221 atcttctact ggacgttttt gaacaactgg gactaccaga ccttctgcac caaattggaa
    32281 ggcttcttct aagtctttac gagttccgac aagagaaccg atgacttgga ttccatcgag
    32341 gactgtttta acgatgctga gttccatcgt ttcagaagga agaccaacag cgacgacgcg
    32401 accaccagca cgaatggagt caacagcctg gttgaaggca actttagaca cagcagttac
    32461 gacagctgaa tgagctcctc catcagtttt ttctttaatg agtccagcta catcttcaac
    32521 ttcgaggccg ttaatcacaa tgtcagcgcc tacttctttt gcaagggcaa gtttgtcatt
    32581 gttgatatcg actgcgataa catgagcatt gaatactttt ttagcgtatt gaacagcgag
    32641 gttaccaagt ccaccagcac cgtaaagaac aacccattgg cctggttcaa cttttgcttc
    32701 tttgatagct ttataggttg ttactccagc acatgtgata gaagaagctt gggctggatc
    32761 aagtccgtca ggaactttga cagcatagtc agcagttacg atacattgtt cagccatacc
    32821 accgtctact gagtagccag catttttcac tgtacggcaa agggtttcgc gaccagttgt
    32881 acagtattcg caagtgccac atccttcaaa gaaccaagca acgctgacgc ggtcaccgac
    32941 tttaaggctt ttcacatctg gagcaatctc tttaacgata ccgatacctt cgtgcccaag
    33001 aacacgtcct gggacttgac caaagtcacc atgagcaacg tggaggtcgg tgtggcaaac
    33061 gccacagtat tcaacttcta caagtgcttc cccagtttca agtggacgga gtactttttc
    33121 ttcaatagca acaccagtgc tttctggatt tacaacaaca gctttcatag ctatcctcct
    33181 tgatattgac cgagaacagg gacaacggga ctggattgat tttttgtcaa cagagtcgag
    33241 tgtgacgagc tctcttgtat ttatatgtga agtatatcac aaaagaaagc cttttccaag
    33301 gttttggaga caaaaagtag aacaatcgat taactggttg atgagactgt gaaaagagca
    33361 caaagaccag cttgcaagct ggtcatactc ttcgaaaatc tcttcaaacc acgtcagctt
    33421 catctacaac ctcaaagcag tgctttgagc aacctacggc tagcttccta gtttgctctt
    33481 tgattctcat tgagtatcag tataggttat aagaataagt cttgtagggt tttggcaacc
    33541 ccatcttggt cgttggtaag ggaaatttgc tcatctgcat aaggaagtag ctctggattg
    33601 gcatttttca tggcataacc cttcccagca aaagcgagca tttcggtatc attgtgttca
    33661 tctccaaagg caatcaaatc ttttttgtca cgattcatta tcttgagcaa gtagtccaaa
    33721 gcaaaggcct tgttgacacc ttttggggta cattcaagga tattgagcgg acctccccag
    33781 gtattgatag aaagttgatg ctggtagaag gcgttcatgt cttttgccaa ggcatatttg
    33841 tcactggctc tggtctgcaa gaggatacag ttagggtcct tggtcaccaa ttcaggctgg
    33901 aattgatctt caggctggaa agcttctaca ccaaatagtt tgggattggc aatctcttca
    33961 ttgggatttg taatgtagaa ttttttacga tattctccag cgataaaatc ggcttgaatg
    34021 tcctctgaac gttgaaccat atctagcaga tattttttgt ctacagtcaa acacttttca
    34081 aaatcccaaa cttggtctgg taaatgagta agggatccgt tgaagttaat cataggagtg
    34141 tctaagccca gttcacggta aaaatctttt gacatacggt aagggcgacc tgtcgtaata
    34201 ataacctgat ggcctttttc agcaactttt ttgatggttt ttttggtaaa gtcagaaatt
    34261 tgactgtctg agttgagcag ggttccatcc aggtcaactg caataatttt tttcgtcata
    34321 tggacctttc tagtgtgttt tcagataaga tgtcttctat tataacagaa agcaggcaga
    34381 aaagcagatt ccaaacaaaa aatgaaattg gattaatttc ttaaacaaat caaacaaaga
    34441 cattgaaaaa gtgaatgata aatgatataa ttctattatt gttcgtaaaa attaaaagga
    34501 gattgatgat ggacaaatta tttaaactaa aagagaacgg tacagacgtt cgtacagagg
    34561 ttctcgctgg tttaacaact ttctttgcaa tgagctatat tctctttgta aacccacaaa
    34621 tactttcaca aacaggaatg cctgctcagg gtgtcttcct agcgacgatt attggtgcag
    34681 tagcgggtac cttgatgatg gctttttatg ctaacttacc ttatgcccaa gcgccaggta
    34741 tgggactcaa tgccttcttt acctttacag ttgtattcgg gcttggttat tcttggcaag
    34801 aagccctagc tatggtcttc atctgtggga ttatttcatt gattattacc ttgacaaagg
    34861 ttcgtaaaat gatcattgaa tcgattccca atgctcttcg ctcagctatt tcagctggta
    34921 tcggtgtctt ccttgcctat gtagggatta agaatgctgg acttttgaaa ttcacgattg
    34981 atccaggcaa ctatactgtt gtaggagaag gggctgacaa agctcaagca acgattgcag
    35041 caaactcttc agcagttcca ggattggtca gctttaataa tccagctgtt ttagtggctc
    35101 ttgcaggact tgccattact atcttctttg tcatcaaagg gattaaaggg ggaattattc
    35161 tctctatctt gacaacaact gttcttgcta ttgcagttgg tttggttgat ttgtctagta
    35221 tcgattttgc taataaccat gttggtgcag cttttgaaga tttgaagaca atctttggtg
    35281 cagctcttgg ttcagaaggt ttaggagctt tggtttcaga tacagctcgc ttgcctgaaa
    35341 ctctgatggc cattcttgcc ttctcattga cagatatttt tgacacaatt ggtaccttga
    35401 tcggtacagg tgaaaaagtt ggtattgtag cgacaaatgg tgaaaatcac caatcagcca
    35461 aattggataa ggctctttac tctgatttga ttggaacgac agtcggtgcc attgcaggta
    35521 cttcaaacgt aacgacttat gttgagtctg ctgctggtat cggtgcaggt ggacgtactg
    35581 gtttgacagc cttggttgta gctatctgtt ttgcgatttc aagcttcttt agcccacttc
    35641 tagcgatcgt accaacagcg gctacagctc caatcttgat tatcgttggg attatgatgc
    35701 ttggtagctt gaaaaatatc cattgggatg atatgtctga agcagttcct gccttcttca
    35761 catctatctt tatgggattc agctactcta tcactcaagg gattgcagtt ggtttcttga
    35821 cttacacttt gactaagctt gttaaaggtc aagttaaaga tgttcatgcc atgatttgga
    35881 ttttggatgc cttgtttatc cttaactaca ttagcatggc cttataatag aatgacccag
    35941 ggggatttcc cccctttttt aatacaaagg agataggtga tgaaagagaa aaatatgtgg
    36001 aaagaattgt tgaatcgtgc aggctggatt ttggtctttt tacttgccgt ccttttatat
    36061 caggttcccc tagtggttac ctctattttg actttaaaag aagtagccct gctacagtca
    36121 gggctgatgg ttgctggcct ttcaattgtg gttctggctc tatttattat gggagctcgt
    36181 aaaaccaagt tagctagttt taatttttct ttttttagag ctaaagattt ggcacgtttg
    36241 ggtttgagtt atttagttat tgtcgggtca aatatacttg gttctatctt gttgcaactg
    36301 tcaaatgaga cgacaacagc taaccagtct cagattaatg atatggttca aaatagttcg
    36361 ttgatttcca gtttcttctt gctagccttg cttgctccga tttgtgagga aatcttgtgt
    36421 cgtgggattg ttcctaaaaa gattttccga ggcaaggaga acttgggatt tgtagtcggt
    36481 acgattgtgt ttgctttatt gcatcaacca agtaatttac cttctttatt gatttatgga
    36541 ggtatgtcga cagttctatc ttggacggcc tacaagaccc aacgtttgga aatgtcgatc
    36601 ttgcttcaca tgattgttaa tgggattgct ttctgtttgt tggctcttgt ggtgattatg
    36661 agtcggacat taggaatttc tgtttaaaag cttttatgta gaaaccgacc tctttctact
    36721 agggaaagat gaatgcaatc gtgtccatct ttttcttttt atggtaaaat agaaaaataa
    36781 taagatgaaa agccttgagg gagtgaccga tatgtcaagt aaagccaatc atgcaaaaac
    36841 agctatttgc ggaattatca atgtaacccc agactccttt tcggacggtg gtcaattttt
    36901 tgctcttgag caggcactcc agcaggctcg taaattgata gcagaaggag ccagtatgct
    36961 cgatatcggc ggagaatcga ctcggccggg cagtagctat gttgagatag aagaggaaat
    37021 ccagcgtgtt gttccagtga tcaaagcgat tcgcaaggaa agtgatgtcc tcatctctat
    37081 tgatacttgg aagagtcaag tagcagaggc tgctttggct gctggtgccg atctagtcaa
    37141 tgatatcact ggtcttatgg gtgatgagaa aatggctcat gtggtagctg aagcgagagc
    37201 gcaagtggtc atcatgttta acccagttat ggctcggcct cagcatccta gttcgcttat
    37261 cttccctcat tttggttttg gtcaaacctt tacagaaaaa gagttagcgg actttgaaac
    37321 attgccaatc gaagaattga tggaggcttt ctttgaacga gcactagcga gagcggcaga
    37381 agctggtatt gcaccagaaa atatcctgtt ggatccagga attggctttg gtctgaccaa
    37441 gaaagaaaat ctgcttcttt tacgggacct ggataaacta catcagaagg gctatccaat
    37501 ctttctcgga gtgtcgcgca agcgatttgt catcaatatc ctagaggaga atggttttga
    37561 agtcaatcct gagacagagc ttggtttccg aaatcgggac acggcttcgg ctcatgtaac
    37621 tagtatcgct gcgagacagg gtgtagaagt ggtgcgcgtg catgacgtag ctagtcacag
    37681 gatggcagtt gaaattgcct ctgccattcg tctggctgat gaagcggaaa atttagattt
    37741 aaaacaatat aaataagatg aaagaaattg aaaacaatca gtggattgct aactaccgga
    37801 cggatcaacc gcattttggc ttggaacgaa tggtggaact gttagctttg cgtggcaatc
    37861 cccatctcaa actcaaggtc ctccatatcg gagggactaa cggcaagggc tcgactattg
    37921 cttttttgaa aaagatgcta gaaaagctag ggttgagagt tggcgtgttt agctcgccct
    37981 atctcattca ttacacagac cagattagca tcaatgggga atcgatctca gaagcgaggc
    38041 tagaagctct catggcagac tatcagtctt tgctggaggg agaagcggtc gccaatttac
    38101 agggcacaac cgagtttgag attatcacag ccctggccta tgactacttt gcctcagagc
    38161 aagtagatgt ggccatcatg gaagttggca tgggtggact tttggatagt accaatgtct
    38221 gtcagcccat tttgacagga attacaacta ttggcttgga tcatgtggcc ctacttggtg
    38281 acaccttgga gtccatagca gagcagaagg caggtattat caaacaaggg atgcccttgg
    38341 taacagggcg tattgctcca gaagccttag ctgtgattga ccgcattgcg gaagagaaag
    38401 atgcgccgag acttgcctac gggacagatt atcaggttcg tcatcaagaa agtgtggtga
    38461 caggggaagt ctttgactat acaagtgctg tcagacaagg ttgcttccag actagcctgc
    38521 ttggtttgta ccaaatagag aatgctggga tggccatagc tttacttgat actttttgtc
    38581 aagaagatgg tcgagagcta gcaagcaatg actttcttgg tcaagccttg gaagaaacaa
    38641 gttggccagg gcgtttggaa atcgtgtcaa gagatccctt gatgattttg gatggagccc
    38701 acaatcccca tgctatcaag gccttgttgg taaccttgca agaacgtttt gcggatcatc
    38761 ataaggaaat cctcttcact tgtatcaaaa ccaaagcctt ggaggatatg ttggacttgc
    38821 tgggagccat gccagatacc gagcttactc taacacattt tgcggatagt cgggcgacgg
    38881 atgaaagcgt gctgaaagag gcagctaagg ctagaaatct cagctaccaa gattggcatg
    38941 attttctaga gcagaatttg acagataaaa aagaagagaa acaaacagtt aggattgtca
    39001 caggttcctt gtatttcttg agccaagtga gggcctatct gatggagagg aagaacgaga
    39061 atggatacac aaaagattga agcagctgta aaaatgatta tcgaggctgt aggagagaac
    39121 gctaatcgcg agggcttgca ggaaacacct gctcgtgtag cccgtatgta tcaagagatt
    39181 ttttcaggtc ttggtcaaac agcagaggaa catttgtcaa aatcctttga aattattgac
    39241 gataatatgg tggtagaaaa ggatatcttt ttccatacca tgtgtgaaca ccacttcttg
    39301 ccattttatg gtagagcgca cattgcctac attccagatg gtcgtgtggc aggcttgtct
    39361 aagctagccc gtacggttga agtttattcg aaaaaaccac aaattcaaga acgtttgaat
    39421 atcgaagtgg ccgatgcctt gatggactat ctaggtgcta aaggagcctt tgttgtcatt
    39481 gaggcggaac atatgtgtat gagtatgcgt ggtgttagaa aaccaggcac tgcaaccttg
    39541 acgacagtag ctcgtggtct atttgaaaca gataaggatc tccgtgacca agcttatcgt
    39601 ttaatggggc tataaaaaga atccgcttca agcggatttt tctagaaagg aatcattatg
    39661 gatcaactgc agattaagga tttggaaatg tttgcctatc atggtctttt tcctagtgag
    39721 aaagaattgg ggcagaaatt tgtcgtttca gccatcctat cctatgatat gaccaaggca
    39781 gctacagact tggatttaac agcctctgtc cattacggag aattgtgtca gcagtggacg
    39841 acttggtttc aggaaacgag tgaagatttg attgaaacgg tagcctataa actggtggaa
    39901 cgtacctttg agtcttatcc tcttgtccaa gaaatgaagt tggaactgaa aaaaccttgg
    39961 gcaccggtgc atttgtcact agatacttgc tcggtaacca ttcatcgccg caagcaacga
    40021 gcctttatcg ccctaggaag caatatggga gataaacaag caaacttgaa gcaagccatt
    40081 gacaaactgc gagctcgtgg catccatatt ctcaaagagt ccagtgtctt agcgacggag
    40141 ccttggggtg gagtggagca ggatagcttt gccaatcaag tggttgaggt ggaaacctgg
    40201 ctaccagcac aagacttgtt agaaaccttg ttagccattg agtcagagct gggacgggtg
    40261 agagaagtgc attggggacc tcgtttgatt gatttggact tgctctttgt ggaggaccag
    40321 atcctttata cagacgacct catattgcct catccttaca tagcggaacg cctttttgtc
    40381 cttgagtcct tacaggaaat tgcgcctcat tttatccatc cgatattaaa acaaccgatc
    40441 cgcaacttgt atgatgcttt gaaaaaatag aaaaactcta gttttcagtc acttgcaact
    40501 gaaggctaga gtttttatac tcttcgaaaa tcaaattcaa accacgtcag cgtcgcctta
    40561 ccgtactcaa gtacagcttg cggttagctt cctagtttgc tctttgattt tcattgagta
    40621 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtcca tgtctaaaac
    40681 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    40741 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    40801 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    40861 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    40921 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    40981 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaagaagg
    41041 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    41101 ataactttca gttactttga gaagttaccg aaaaatattt ttcatatcta ttgactttta
    41161 ggggtaaaat ttggtatgat agtaggcggt attgtttacc ccatttgaaa ggccccggaa
    41221 ccttccaaat acttttcgat gggaaggaac acccatcacc gtaaacaaaa atcgaactat
    41281 atataggaga aatcatgaac aaaacaacat ttatggctaa accaggccaa gttgaacgta
    41341 aatggtacgt agttgacgca actgatgtac cacttggacg tctttctgca gtagttgcta
    41401 gcgtacttcg cggaaaaaac aaaccaacat ttacaccaca cactgataca ggtgacttcg
    41461 tgattgttat caatgctgaa aaagttaaat tgactggtaa aaaagcaact gataaaatct
    41521 actacactca ctcaaaccac ccaggtggat tgaaacaaat ctctgcaggt gaacttcgtt
    41581 ctaaaaatgc agtacgtttg attgagaaat cagttaaagg tatgcttcca cacaatacac
    41641 ttggacgcgc tcaaggtatg aagttgaaag tatttgttgg agctgagcac actcacgctg
    41701 cacaacaacc agaagttctt gacatttcag aacttatcta aggaaaggaa caataaagta
    41761 tgtcacaagc acaatatgca ggtactggac gtcgtaaaaa cgctgttgca cgcgttcgcc
    41821 ttgttccagg aactggtaaa atcactgtta acaaaaaaga tgttgaagag tacatcccac
    41881 acgctgacct tcgtcttgtc atcaaccaac cattcgcagt tacttcaact gtaggttcat
    41941 acgacgtttt cgttaacgtt gtaggtggtg gatacgctgg tcaatcagga gctatccgtc
    42001 acggtatcgc tcgtgccctt cttcaagtag acccagactt ccgcgattca ttgaaacgcg
    42061 caggacttct tacacgtgac tcacgtaaag ttgaacgtaa gaaaccaggt cttaagaaag
    42121 ctcgtaaagc atcacaattt agtaaacgtt aattcgaaag aattactata cttatacaga
    42181 gcacctttcg gggtgttctt tttttatact ttcttactaa attggtgcaa ttgacacagt
    42241 tgttgcgact ttagtcgctt acaaatgtgg ctgcaacctg acaaggtcag ttgcctcaaa
    42301 acgttaatca atacgattat atcaatgttt caaagcactc aaaagtttac cttattttta
    42361 tagtaaggtg aaataagaat aggacaaacc gaggataatc aaatcgaatt ctaacaatgt
    42421 tttagaagta gaggtgtact attctagttt caatctact
//
LOCUS       DAVLBN010000012        40284 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLBN010000012 DAVLBN010000000
VERSION     DAVLBN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.012"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..89
                     /locus_tag="VXC24_000619"
     tRNA            19..89
                     /locus_tag="VXC24_000619"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51..53,aa:Gly,seq:tcc)
     gene            124..197
                     /locus_tag="VXC24_000620"
     tRNA            124..197
                     /locus_tag="VXC24_000620"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:158..160,aa:Ile,seq:gat)
     gene            280..369
                     /locus_tag="VXC24_000621"
     tRNA            280..369
                     /locus_tag="VXC24_000621"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:316..318,aa:Ser,seq:tga)
     gene            380..453
                     /locus_tag="VXC24_000622"
     tRNA            380..453
                     /locus_tag="VXC24_000622"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Met,seq:cat)
     gene            457..529
                     /locus_tag="VXC24_000623"
     tRNA            457..529
                     /locus_tag="VXC24_000623"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Phe,seq:gaa)
     gene            542..622
                     /locus_tag="VXC24_000624"
     tRNA            542..622
                     /locus_tag="VXC24_000624"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:576..578,aa:Tyr,seq:gta)
     gene            627..697
                     /locus_tag="VXC24_000625"
     tRNA            627..697
                     /locus_tag="VXC24_000625"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:659..661,aa:Trp,seq:cca)
     gene            712..784
                     /locus_tag="VXC24_000626"
     tRNA            712..784
                     /locus_tag="VXC24_000626"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:His,seq:gtg)
     gene            795..866
                     /locus_tag="VXC24_000627"
     tRNA            795..866
                     /locus_tag="VXC24_000627"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Gln,seq:ttg)
     gene            876..959
                     /locus_tag="VXC24_000628"
     tRNA            876..959
                     /locus_tag="VXC24_000628"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:910..912,aa:Leu,seq:caa)
     gene            1066..2343
                     /locus_tag="VXC24_000629"
     CDS             1066..2343
                     /locus_tag="VXC24_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0492781.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2419..3903
                     /locus_tag="VXC24_000630"
     CDS             2419..3903
                     /locus_tag="VXC24_000630"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0492782.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3964..5244
                     /locus_tag="VXC24_000631"
     CDS             3964..5244
                     /locus_tag="VXC24_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0492783.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5248..5868
                     /locus_tag="VXC24_000632"
     CDS             5248..5868
                     /locus_tag="VXC24_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0492784.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6034..7176
                     /locus_tag="VXC24_000633"
     CDS             6034..7176
                     /locus_tag="VXC24_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0492785.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7582..7920
                     /locus_tag="VXC24_000634"
     CDS             7582..7920
                     /locus_tag="VXC24_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0492786.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7931..8289
                     /locus_tag="VXC24_000635"
                     /pseudo
     CDS             7931..8289
                     /locus_tag="VXC24_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8396..9013
                     /gene="pcp"
                     /locus_tag="VXC24_000636"
                     /pseudo
     CDS             8396..9013
                     /gene="pcp"
                     /locus_tag="VXC24_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9041..9898)
                     /locus_tag="VXC24_000637"
     CDS             complement(9041..9898)
                     /locus_tag="VXC24_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0492787.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10028..11170
                     /gene="tgt"
                     /locus_tag="VXC24_000638"
     CDS             10028..11170
                     /gene="tgt"
                     /locus_tag="VXC24_000638"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0492788.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11268..13085
                     /locus_tag="VXC24_000639"
     CDS             11268..13085
                     /locus_tag="VXC24_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0492789.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13238..14389
                     /gene="nagA"
                     /locus_tag="VXC24_000640"
     CDS             13238..14389
                     /gene="nagA"
                     /locus_tag="VXC24_000640"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0492790.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14552..15610
                     /locus_tag="VXC24_000641"
     CDS             14552..15610
                     /locus_tag="VXC24_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0492791.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15761..16126
                     /locus_tag="VXC24_000642"
     CDS             15761..16126
                     /locus_tag="VXC24_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0492792.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16202..17143
                     /locus_tag="VXC24_000643"
     CDS             16202..17143
                     /locus_tag="VXC24_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0492793.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17091..18107
                     /locus_tag="VXC24_000644"
     CDS             17091..18107
                     /locus_tag="VXC24_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0492794.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18109..18435
                     /gene="comGC"
                     /locus_tag="VXC24_000645"
     CDS             18109..18435
                     /gene="comGC"
                     /locus_tag="VXC24_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0492795.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18404..18832
                     /locus_tag="VXC24_000646"
     CDS             18404..18832
                     /locus_tag="VXC24_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0492796.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18837..19097
                     /locus_tag="VXC24_000647"
     CDS             18837..19097
                     /locus_tag="VXC24_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492797.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19060..19521
                     /locus_tag="VXC24_000648"
     CDS             19060..19521
                     /locus_tag="VXC24_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0492798.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            19499..19912
                     /locus_tag="VXC24_000649"
     CDS             19499..19912
                     /locus_tag="VXC24_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0492799.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20049..20636
                     /locus_tag="VXC24_000650"
     CDS             20049..20636
                     /locus_tag="VXC24_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0492800.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20697..21650
                     /locus_tag="VXC24_000651"
     CDS             20697..21650
                     /locus_tag="VXC24_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0492801.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21701..22891
                     /locus_tag="VXC24_000652"
     CDS             21701..22891
                     /locus_tag="VXC24_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0492802.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23040..23411
                     /gene="rnpA"
                     /locus_tag="VXC24_000653"
     CDS             23040..23411
                     /gene="rnpA"
                     /locus_tag="VXC24_000653"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0492803.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23386..24210
                     /locus_tag="VXC24_000654"
     CDS             23386..24210
                     /locus_tag="VXC24_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0492804.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24229..25215
                     /locus_tag="VXC24_000655"
     CDS             24229..25215
                     /locus_tag="VXC24_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0492805.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25266..25889
                     /locus_tag="VXC24_000656"
     CDS             25266..25889
                     /locus_tag="VXC24_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0492806.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26020..27477
                     /locus_tag="VXC24_000657"
     CDS             26020..27477
                     /locus_tag="VXC24_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0492807.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27500..27781
                     /locus_tag="VXC24_000658"
     CDS             27500..27781
                     /locus_tag="VXC24_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0492808.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27858..28343
                     /locus_tag="VXC24_000659"
     CDS             27858..28343
                     /locus_tag="VXC24_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0492809.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28360..29025
                     /locus_tag="VXC24_000660"
     CDS             28360..29025
                     /locus_tag="VXC24_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0492810.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29029..29892
                     /locus_tag="VXC24_000661"
     CDS             29029..29892
                     /locus_tag="VXC24_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0492811.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29894..30598
                     /locus_tag="VXC24_000662"
     CDS             29894..30598
                     /locus_tag="VXC24_000662"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0492812.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30777..32450
                     /locus_tag="VXC24_000663"
     CDS             30777..32450
                     /locus_tag="VXC24_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0492813.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32562..33653
                     /gene="ulaG"
                     /locus_tag="VXC24_000664"
     CDS             32562..33653
                     /gene="ulaG"
                     /locus_tag="VXC24_000664"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0492814.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33767..35743
                     /gene="tkt"
                     /locus_tag="VXC24_000665"
     CDS             33767..35743
                     /gene="tkt"
                     /locus_tag="VXC24_000665"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0492815.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35860..36159
                     /gene="yajC"
                     /locus_tag="VXC24_000666"
     CDS             35860..36159
                     /gene="yajC"
                     /locus_tag="VXC24_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0492816.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36206..36634
                     /locus_tag="VXC24_000667"
     CDS             36206..36634
                     /locus_tag="VXC24_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0492817.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36636..37046
                     /locus_tag="VXC24_000668"
     CDS             36636..37046
                     /locus_tag="VXC24_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492818.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37347..39998
                     /gene="adhE"
                     /locus_tag="VXC24_000669"
                     /gene_synonym="adhC"
     CDS             37347..39998
                     /gene="adhE"
                     /locus_tag="VXC24_000669"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0492819.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12217 a         7208 c         9079 g        11780 t
ORIGIN      
        1 ccgttaactc ccattttagc gggtgtagtt tagtggtaaa actacagcct tccaagctgt
       61 tgtcgcgagt tcgattctcg tcacccgctt tgaactttgt tctttgtacc aagtttttga
      121 cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg tcggtggttc
      181 gagtccactc gtgcccatag tgtttagtcc attactaggg gattggaata ttatctgttc
      241 actaagagga cacgggcttg ttcccgtata aactattttg gaggattacc caagtccggc
      301 tgaagggaac ggtcttgaaa accgtcaggc gtgtaaaagc gtgcgtgggt tcgaatccca
      361 catcctcctt ttatattaac gcgggatgga gcagctcggt agctcgtcgg gctcataacc
      421 cgaaggtcgt aggttcaaat cctgctcccg caataaggct cggtagctca gttggtagag
      481 caatggattg aagctccatg tgtcggcggt tcgattccgt ctcgcgccat ttatatattt
      541 tggaagggta gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg
      601 ggttcgaatc cctccccttc cattttacgg gcatagttta aaggtagaac taaggtctcc
      661 aaaaccttca gtgtgggttc aattcctact gcccgtgtta atagaattat ggcgggtgtg
      721 gtgaagtggt taacacacca gattgtggct ctggcatgcg tgggttcgat ccccatcact
      781 cgcctatttt atattggggt atagccaagc ggtaaggcaa gggactttga ctccctcatg
      841 cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa ttggcagacg
      901 cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat
      961 agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat
     1021 tatagttatt caaattttgt ttagattgag aaagtgtagg gtagtatgtc ttgttctatc
     1081 gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga
     1141 attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata
     1201 aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat
     1261 tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt
     1321 tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat
     1381 cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt
     1441 gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca
     1501 cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta
     1561 catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca
     1621 aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat
     1681 ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc aagggatatt
     1741 ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc
     1801 cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa
     1861 cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt ggctacgcct
     1921 gaaatccaag catttgctct gaatggggat gaggttatta tttcccccca agagaaggat
     1981 tttgaaactc atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt
     2041 cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga
     2101 ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta
     2161 tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct tacagatgag
     2221 gaagaaacta cgattattga attttccaaa gacttactcc tactagctga ggagggacta
     2281 gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta
     2341 taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata
     2401 gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca
     2461 gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg
     2521 gttacttatc caaaggtaga tttggacttt gacaaattga aagatgcttc ttaccaggaa
     2581 gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga gttggactac
     2641 tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcact attagtgaaa
     2701 ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg
     2761 gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac
     2821 aagattgtta tattgacagc gacatctggt gacacgggga aagctgctat ggcggggttt
     2881 gcggatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt cagcaagatt
     2941 caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc tattgatggt
     3001 aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgatgtggc tcttcgtgaa
     3061 aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat tggtcgtctg
     3121 gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac tggtgaaatt
     3181 gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa tatcttggct
     3241 gccttttatg ccaaacaaat tggtttgcca gttggtaaat tgatctgtgc ttcaaatgac
     3301 aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg tgagtttaag
     3361 gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg cttgattttc
     3421 catcttttgg gaaataatgc tgaaaagaca gctgaactca tgaatgcttt gaacatgcaa
     3481 ggacaatata agttgacaga ctttgatgca gagattctgg agctctttgc agctgaatat
     3541 gcgactgagg aagaaacagc ggcagaaatc aagcgtgttt atgagttaga ttcttatatt
     3601 gaggatccac atacggcggt tgcctcagca gtttatagaa aataccaagc ggttactgat
     3661 gatgcgacta agacagtgat tgcttcaaca gctagtccct acaagttccc agtagttgca
     3721 gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc tcaattacat
     3781 gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgagacagc tcctgttcgt
     3841 cacaagacaa ctgtagcggc tgctgatatg caagcagcgg ttgaggctta tttaggactt
     3901 taagatagag ggagtaaact cggttgggaa accaactgag tttcttttca tcaggaggag
     3961 agattgttta agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac
     4021 tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata
     4081 gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc
     4141 gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg
     4201 aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta
     4261 ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat
     4321 gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt
     4381 ttaatgacta gtctgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat
     4441 gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg
     4501 gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt tggtcttgtg
     4561 attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt agataaggaa
     4621 ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc tggagatgta
     4681 gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga
     4741 gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc aacggtcatg
     4801 ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa
     4861 accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt
     4921 gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg
     4981 acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc
     5041 tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt
     5101 atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt
     5161 tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag
     5221 cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac
     5281 gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctcag
     5341 ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa
     5401 aatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg
     5461 cgtgcccaga gtctggctga gaaaaatgct caggtagttt tgatgccagg tgcgcgtgag
     5521 gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac
     5581 aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga gattttaacc
     5641 agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag
     5701 tatcagttga attctgataa tacttattat ataggggatc ggactctgga tgtggaattt
     5761 gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga agggaatcac
     5821 aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata aaaagattgt
     5881 gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg ttacaaggaa
     5941 tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatgat
     6001 agacaggtac taatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca
     6061 acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt tctttggact
     6121 gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa aacaagttat
     6181 accgtacagt atggtgatac cttgagcact attgcagaag ccttgggtgt agatgtcaca
     6241 gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg
     6301 acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac acctcaagca
     6361 gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca agtgaccgtt
     6421 gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc tccaaaagaa
     6481 gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt ggcaccatct
     6541 acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt tgcagaagaa
     6601 gctcctcagg aaacgactcc aggtgagaag caggaaacac aagcaagccc tcaagcagca
     6661 tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga
     6721 gctacagcag cagtttctac ttatcaacca gaagagacga aaataatttc aacaacttac
     6781 gaggctccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga aaatgcaggt
     6841 cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc
     6901 tttagtggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgatttt
     6961 atggtaccag aaagttcaga attaggggat aagattgcgg aatatgctat tcaaaacatg
     7021 gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc
     7081 aaatatgggc cagctaacac ttggaatcca atgccagacc gtggtagtgt gacagaaaat
     7141 cactatgacc acgttcacgt ttcaatgaat ggataaaccc gacttggtaa catcattttg
     7201 acgaatgaga tctagctttc gtgataggaa gcgattctcg ttcgtttttt ctttgtcata
     7261 ctcttcgaaa atctcttcaa accacgtcag ttttatctga aacctcaaag ctgtgctttg
     7321 agcaacctgc gactagcttt ctagtttact ctttgatttt cattgagtat caatttgaat
     7381 ggaaaatgga aagttattat cttgtaataa tccaagcaac attcttgcaa tctattttac
     7441 tttatatcac aattgattgg tcaactattg ataagtcaat ggataggagg aagaaatgat
     7501 agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta cgcaattgtt
     7561 tgaaaaaggc ttgggattag tttgacacgg tatcagattt tactgttttt gctggagcat
     7621 tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc tgctttgaca
     7681 cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa tcctgaaaat
     7741 cagcgggaag tgttggtaga ggctgcgaag tatgccaagg agcagttagt ggtgaatccc
     7801 cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga gtttgagaga
     7861 acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat agaaatttaa
     7921 ggagaaatag atgtcaatta ttttaacaac gatcgttgct ttggagcatt tttacatttt
     7981 ttatttggaa agtattgcca cgcaatcaga tgcgactagt cgtgtattta atatggaaaa
     8041 ggaagaattg gctcatccgt cagtaagttc attgttcaaa aatcaaggaa tttataaggc
     8101 tctgctagga gtctttctct tgtatgtcat ttatttctca cagaatttag aaattgtgac
     8161 tatttttgtc ttatttgtga ttggtgctgc gacttacggc tctttaacag cggataaaaa
     8221 attattttga agcaaggtgg atcagctatt ttggccttga ttagtatttt actctttaaa
     8281 tacacttgaa ggttgattct aatctcgcta atccttttta atccagaata agggaaatat
     8341 gttatacttg tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa
     8401 agtattagtg acaggttttg agcccttttg aggccattaa aggtttacca gctgaaatcc
     8461 atggtgctga ggtccgttag ctagaggtgc cgacagtttt tcacaaatct gctcaagtat
     8521 tggaagaaga gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg
     8581 gaagaactag tttgacacct gaacgagtgg ccattaatca agacgatgca cgcatttctg
     8641 ataacgaaga taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact
     8701 ttagtagttt gccgattaaa gcgatggttc aagctataaa aaagagggct taccggcctc
     8761 tgtttccaat acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt
     8821 ggtagaaaag aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga
     8881 acaggtggtg aacagacaga ctattccagc tatgagttta gtggatattc ggagagggat
     8941 agaagcagca atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg
     9001 agaaactcat tgatagaaaa aagcttgagt ggaaaaacct tcaagctttt ggacgttttc
     9061 gagccaatac tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa
     9121 aactagcaat gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta
     9181 ggacaaagcg ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc
     9241 ttggtgggac ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg
     9301 cataatactg tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa
     9361 agtagagtcc aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg
     9421 gaaactcagg atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt
     9481 aaatcccaag taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg
     9541 tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg
     9601 gctccgtttt agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa
     9661 tagtcccgat aaagaagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta
     9721 tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac
     9781 tagataagat gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag
     9841 cctgaaaatg ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc
     9901 tcttattata ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa
     9961 tcatacagtg tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag
    10021 gtaaaaaatg tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg
    10081 agctcgtctg ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc
    10141 agttgggaca caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc
    10201 gggaattatc ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc
    10261 acgcgctggt ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg
    10321 tggttttcag gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt
    10381 taaaaatcat ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca
    10441 gaataatctg ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc
    10501 ttatgactac gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa
    10561 ggctcaccgt cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga
    10621 agaccttcgc cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat
    10681 cggtggtttg gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac
    10741 tcaactgcta cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt
    10801 gatcgatggg gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc
    10861 tcgtaacggg acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc
    10921 tgaggacttt acgccactgg atcctgagtg tgactgctac acatgtaata actatacacg
    10981 cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta
    11041 ccacaatctt tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga
    11101 caatctcttg gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg
    11161 taatttctaa aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc
    11221 tttttttgat agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat
    11281 ggttttcctt gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga
    11341 cgatctttcc tggaggattc ttcggggtag atgtcttttt cacattttca ggtttcctga
    11401 ttacagctct actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt
    11461 ttagaagacg cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc
    11521 cttttacttt cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg
    11581 tcttaggctt tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt
    11641 tcattcctca tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc
    11701 tttggggatt ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg
    11761 ggatggtctt tctcttatct gctgctgcct tcttgatcag tttcttctcc atgtttattg
    11821 gtagttttct agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc
    11881 cattcttttt gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg
    11941 tcaagcagtt ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct
    12001 ttggtttcct agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta
    12061 tcggcttctt gcttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac
    12121 atgaaaagac acatcatata caggagccga agattatcag ctttttagcg gatactagct
    12181 atgcggttta tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc
    12241 ttcttgctgt attactgact ctgatttgtt cttatggctt tgccagtctg tcattctatg
    12301 tattggaacc ttggattgca ggcaagaaca cacctatttt acaaactctt cgtcccctgc
    12361 cttatattca cgcaattctt gcagcaggta caggaatctt gaccttcatt gtctgcatgg
    12421 tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga
    12481 agcaagctgc aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca
    12541 gtttgggaat tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata
    12601 cagcactaca gacagttctt cctggagcac agattaacgc gcaggtcagc gtaacaacca
    12661 agaccgcaaa tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg
    12721 tcattgcgac tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga
    12781 aaaatcttcc taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa
    12841 aagagaccta tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga
    12901 caccttacat tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg
    12961 caggaacaga ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat
    13021 tgtatgcaga tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa
    13081 aataacttgt attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca
    13141 aaaaataggt ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa
    13201 taaattgtag aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga
    13261 tcagtttttc tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa
    13321 gtttgggaaa catgtagagc agattcctga aggggctgag gtgattgact atacaggtta
    13381 tagcattgcc ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat
    13441 ggacaacaac attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt
    13501 taccagtttc ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga
    13561 aaatcttgga aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga
    13621 aggtccatat ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc
    13681 gggtgttgag gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc
    13741 ccttgcacca gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt
    13801 gacggttgct cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc
    13861 tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt
    13921 gggtatggtt ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg
    13981 tcaccacgta gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat
    14041 cgctcttatc acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg
    14101 agaattccca gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc
    14161 aggttctatc ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa
    14221 tccgcatgaa gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga
    14281 cgtctgtggc caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt
    14341 ggaattggta gcaacctacc tagatggcgt gaaacgttat caagcataag agagaaagca
    14401 gaagttagag actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt
    14461 aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa
    14521 tattacaaat aaaaaaacgg aggagtgctt tatgaaagct tatacttatg ttaaaccagg
    14581 acttgcttct tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt
    14641 gcgtattgta aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc
    14701 tacttgccaa agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg
    14761 ggaaggagtt tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg
    14821 tggtaaatgc tactactgta aaaaaggaat ttatgcccac tgtgaagacg aagggggctg
    14881 gattttcggt cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga
    14941 taatactctt taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga
    15001 cattctgcct actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag
    15061 cgtagccatt attggttcag gtccagttgg attggctgct cttttaacag cccaattcta
    15121 ttcaccagct aaattgatta tggtagacct agacgataac cgtttggaaa ctgccctatc
    15181 attcggtgcg actcataagg taaactcttc agaccctgaa aaagcgataa aagaaattta
    15241 tgatttgaca gatggtcgcg gtgtagatgt cgctattgaa gctgtaggga ttcctgaaac
    15301 atttgatttc tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca
    15361 tggtaaacca gttgaattcg atttagataa actttggatt cgtaacatca atgtaacaac
    15421 tggtttggta tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat
    15481 tgaaccggaa aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga
    15541 agtcttcagt aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc
    15601 agaagcctaa gtagtaaaaa tatttttgta cataagcaaa tagaaattca gtcatccatc
    15661 agatggctgg attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc
    15721 ggaattggtt ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat
    15781 gtacggagat tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag
    15841 tagaaaattt gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt
    15901 agaacaagaa tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc
    15961 ggaagaccaa cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc
    16021 tcttttgcag gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca
    16081 aaccagtcag gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt
    16141 tttggagttg ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag
    16201 tatggttcaa gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga
    16261 catttatttt gtccctaagt tagatgccta tgagcttcat atgagggtag gagacgagcg
    16321 ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt
    16381 tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc
    16441 ctatgaccag aagatggcgt ctctacgttt atctactgta ggcgattatc gggggcatga
    16501 gagtttggtt atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga
    16561 tattgaagaa ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt
    16621 tgggagtggt aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca
    16681 agttatgtcc atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt
    16741 gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc
    16801 agatctcttg attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc
    16861 tagtttgaca ggtgcgacag tcttttcaac cattcacgcc aaaagtatcc gaggtgttta
    16921 tgagcgtctg ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt
    16981 ctgctaccag agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca
    17041 agaacaccaa gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat
    17101 cacaagtctt caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca
    17161 ccctatttaa caatctcttt tctagcggtt ttcatctggt ggagaccatc tcctttttag
    17221 ataggagtgc tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg
    17281 ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt
    17341 tatctctagc tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc
    17401 tagacaatct ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt
    17461 tgctgggttt tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg
    17521 atagtagcaa tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg
    17581 tagggcttgt ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga
    17641 tgagtgtctt ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact
    17701 tgacagccta ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc
    17761 agatttttca aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc
    17821 tggctcaaac cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct
    17881 ttaggaagga attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg
    17941 agttggaaat ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca
    18001 tgaatttggt gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg
    18061 cggcaatgct catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg
    18121 atgacattct tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc
    18181 ttgctgatta tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa
    18241 gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt
    18301 tatagcttgg aaaagaatga agatgctagc ctaagcaagt taaaagacga tgggcgaatc
    18361 acggaagaac aggttaaagc ttataaagaa tacaatgata aaaatggagg agcaaatcgt
    18421 aaagtcaatg attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag
    18481 tatccttgcc ttgggcttgt ccggctctgt tcagtccact tttgcggcag tagaggaaca
    18541 gattttcttt atggaatttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag
    18601 tcagcaaaag actagtctga acttagatgg gcagatgatt agcaatggca gtcaaaagtt
    18661 gccagtccct aaaggaattc aggccccatc aggccaaagt attatatttg accgtgctgg
    18721 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    18781 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    18841 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    18901 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    18961 gggtagctaa gatggccttg cagacggggc aaaatcagat aaacatcaac ggagttgaga
    19021 ttcaggtatt ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg
    19081 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgct tgccctgctt
    19141 gtcatcagtg ggggcttact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19201 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca
    19261 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19321 ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt
    19381 ggacgaggtt atcagcctat ggtttatggg ctcaaatccg cacagattac agaggacaat
    19441 caactggtgc gctttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19501 gtggaaaaag aaaaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat
    19561 ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc
    19621 tttaaataaa gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga
    19681 gcaagaaagt ggggaacagg tctttaatct aggtcaggta agctatcaaa acaagaaaac
    19741 aagcttggtg acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt
    19801 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa
    19861 agtggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    19921 actataatgc gttgaatcca gaatagttca ctgtagtttc tagaaaattg ctggaaatgg
    19981 atgttaagct ccaatttatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa
    20041 ctaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgattcc cctaaaaata
    20101 tcttcctcgc aaacttggta tgtcaagcag tcgagaaaca gattgatatt ttatcagaca
    20161 aagaaatttt agatttcggt ggtggcacgg gtctattagc cttgccccta gccaagcagg
    20221 ctaagtcagt tactcttgta gacatttctg agaaaatgtt ggagcaagct catttgaaag
    20281 cggagcagca agcaatcaag aatatccagt ttttggagca agatttaccg aaaaatccct
    20341 tggagaaaga gtttgattgc cttgctgtta gtcgggttct tcatcatatg cctgatttgg
    20401 atgcggctct ctcactgttt catcaacatt tgaaggaaga tgggaaactc atcattgctg
    20461 attttaccaa gacagaagct aatcatcatg gatttgattt agctgaactg gaaaacaagc
    20521 taattgagca tggtttttca tctgtgcata gtcagattct ctatagcgct gaagacttgt
    20581 ttcaaggaaa tcactcagaa ttctttttaa tagtagccca aaaatcactc gcctagtcag
    20641 ggagtgattt ttctataagg atggaaaaaa gaagggaaat ttgataagat aggaatatgg
    20701 attttgaaaa aattgaacaa gcttatacct atttactaga gaatgtccaa gtcatccaaa
    20761 gtgatttggc gaccaacttt tatgacgcct tggtggagca aaacagcatc tatctggatg
    20821 gtgaaactga gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt ttagcactac
    20881 gcaaagaaga atggctcaag acctaccagt ttctcttgat gaaggctggg caaacagaac
    20941 ccttgcaggc caatcaccag tttacaccgg atgctattgc tttgcttttg gtgtttattg
    21001 tggaagagtt gtttaaagag gaggaaatta ctatcctcga aatgggttct gggatgggaa
    21061 ttctaggcgc tactttcttg acctcgcttg ataaaaaggt ggattacttg ggaatggaag
    21121 tggatgattt actgattgat ctggcagcta gcatggcaga tgtaattggt ttgcaggctg
    21181 gctttgtcca aggagatgcc gttcgtccac aaatgctcaa agaaagcgat gtggtcatca
    21241 gtgacttgcc tgtcggctat tatcctgatg atgccgttgc gtcgcgtcat caagttgctt
    21301 ctagccaaga acatacttac gcccatcact tgctcatgga acaaggattt aagtacctta
    21361 agtcagatgg atatgctatt tttctagctc cgagtgattt gttgaccagt cctcaaagtg
    21421 atttgttgaa agtctggttg aaagaggagg caagtctggt tgctatgatt agtctgcctg
    21481 aaaatctctt tgctaatgct aaacaatcta agactatttt tatcctacag aagaaaagtg
    21541 aaatagcagt ggagcttttt gtttatccac ttgctagctt gcaagatgca agtgttttaa
    21601 tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac tgaaatataa aatagatttt
    21661 gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa caattgcaat
    21721 caatgcagga agttcaagct taaaatggca attatactta atgccagagg aaaaagtatt
    21781 ggcgaaaggc ttgattgaac gtatcggttt gaaagattca atttcaactg taaaatttga
    21841 cggccgttct gaacaacaaa ttttggatat cgaaaatcat acacaagccg ttaaaatttt
    21901 attggatgac ttgattcgtt tcgatattat caaggcttat gacgagatta caggtgttgg
    21961 ccaccgtgtt gtagcaggtg gagaatattt caaagaatca acagttgttg agggagatgt
    22021 tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta cacaacccgg ccaatgcagc
    22081 aggtgttcgt gccttcaagg aattgttgcc agacattacc agtgtagttg tttttgatac
    22141 ttccttccac acaagtatgc cagagaaagc ttatcgctac cctctaccaa caaaatatta
    22201 cacagaaaac aaggttcgta aatacggtgc tcatggtaca agtcaccagt ttgtagcagg
    22261 agaagctgca aaactcttgg gacgtccatt agaagacttg aagttaatta cctgtcatat
    22321 tggtaacgga ggctcaatta cagctgtgaa agccggcaaa tctgtagaca cttctatggg
    22381 gttcactcct cttggtggta ttatgatggg aacgcgtaca ggggatattg atccagctat
    22441 cattccttat ttaatgcaat atacagagga ttttaacaca ccagaagata tcagtcgtgt
    22501 tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat tctagcgata tgcgcgatat
    22561 agaagcagct gtagcagaag ggaatcacga ggctagcttg gcttatgaaa tgtatgttga
    22621 ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta aatggaacag atgccattgt
    22681 tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa tctcagggat
    22741 ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta caggagacat
    22801 ctcaacagag gcagctaaaa tccgtgtctt ggttattcca acagatgaag aattagtcat
    22861 tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt caatacaagg
    22921 agttgggaaa gttatttttc cagcttcttt ttctgatgaa attgtccaaa accttgctat
    22981 gattggcttt tttgaaaaat atggtataat agtagtaatt taatagatgg agttgagttt
    23041 tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa ggcgattttc aaggagggga
    23101 caagttttgc taatcgcaaa tttgtggtct accaattaga aaaccagaaa aaccattttc
    23161 gagtaggtct atcagttagc aaaaaactgg ggaatgccgt cactagaaat caaattaagc
    23221 gacggattcg gcatattatc cagaatgcaa aagggagtct ggtagaagat gtcgactttg
    23281 ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc agagatggag aaaaatctac
    23341 tccatgtatt aaaattatca aagatttacc gggaaggaaa tgggagtgaa aaagaaacta
    23401 aagttgacta gtttgctagg actgtctctg ttaatcatga cagcctgtgc gactaatggg
    23461 gtaactagcg atattacagc cgaatcggct gatttttgga gtaaattggt ttacttcttt
    23521 gcggaaatca ttcgcttttt atcgtttgat attagtatcg gagtggggat tattctcttt
    23581 acggtcttga ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt ggcttctagg
    23641 aaaatgcagg aagctcagcc acgcattaag gcgcttcgag aacaatatcc aggtcgagat
    23701 atggaaagca gaaccaaact agagcaggaa atgcgtaaag tatttaaaga aatgggtgtc
    23761 agacagtcag actctctttg gccgattttg attcagatgc cggttatttt ggccctgttc
    23821 caagccctat caagagttga ctttttaaag acaggtcatt tcttatggat taaccttggt
    23881 agtgtggata caacccttgt tcttccgatt ttagcagcag tattcacctt tttaagtact
    23941 tggttgtcca acaaagcttt gtctgagcga aatggcgcta cgactgcgat gatgtatggg
    24001 attccagtct tgatttttat ctttgcagtt tatgcgccag gtggagtcgc cctatactgg
    24061 acagtgtcta atgcttatca agtcttgcaa acctatttct tgaataatcc attcaagatt
    24121 atcgcagagc gcgaggccgt agtacaggca caaaaagatt tggaaaatag aaaaagaaaa
    24181 gccaagaaaa aggctcagaa aacgaaataa ataaggagga atctggtaat ggtagtattt
    24241 acaggttcaa ctgttgaaga agcaatccag aaaggattga aagaattaga tattccaaga
    24301 atgaaggctc atatcaaagt catttctagg gagaaaaaag gctttcttgg tctatttggt
    24361 aaaaaaccag cccaagtgga tattgaagcg attagtgaaa cgactgttgt caaagcaaat
    24421 caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc tgtgaagacg
    24481 gttagtgaag aaaccgttga ccttggtcat gtagttgatg ctattaaaaa aatagaggaa
    24541 gaaggtcaag gtatttctga tgaagtcaag gctgaaatct taaaacatga aagacatgcc
    24601 agcactatct tagaagaaac tggtcacatt gagattttaa atgaacttca aatcgaggaa
    24661 gcgatgaggg aagaagcagg cgctgatgac cttgaaactg agcaagacca agctgaaagt
    24721 caagaactag aagacttggg cttgaaagtt gaaacgaact ttgatattga acaagtagct
    24781 acggaagtaa tggcttatgt tcaaacgatt attgatgaca tggatgttga ggctacactt
    24841 tcaaatgatt ataaccgtcg tagcatcaat ttgcaaattg atactaacga accaggtcgt
    24901 attatcggct accatggtaa agtcttgaag gccttgcaac tgttggctca aaattatctt
    24961 tacaactgct attcaagaac cttctatatc actattaatg tcaatgatta tgttgaacac
    25021 cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga ttcgtgtttt agaagaagga
    25081 cgcagtcatc aaacagatcc aatgtcgaat agtgaacgca agattatcca ccgtattatt
    25141 tcacgtatgg atggcgtgac cagttactct gaaggtgatg agccaaatcg ctatgtcgtt
    25201 gtagatacag aataagtaaa atcagggttg acctgatttt ttgctagcta gaggaggtta
    25261 aactgatgtt gaataagata agagactatc tagacttttc tggtttgcag taccgtagtc
    25321 ctgataaagc gggagcagag cgagagaaga tgctggcatt ccgtcacaaa ggacaagagg
    25381 cccgaaaggc ttttacagaa ctggccaaag cctttcaagc aagccatcca gaatggcaac
    25441 tccaacagac tagtcagtgg atgaatcagg cccagcgttt gagaccacat ttttgggttt
    25501 atctacagag agacggacaa gtgacagaac ctatgatggc cttacgtttg tatgggacat
    25561 ctactgactt tggaatttct ttggaagtca gtttcatcga acgtaagaag gatgagcaaa
    25621 ctttagagaa acaggccaag attttagaca ttccaaccgt taaaggaatt tattatctag
    25681 cctactctga tggccaaagt caacggtggg aggcgaacga agaaaagcgt cgtactttac
    25741 gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt gaaggtagat gttcctatga
    25801 cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat tctaaaattc
    25861 ttccctatta tctagctacg agaaaataag ataatttgta aaacatcata aatcatacag
    25921 tccaagagtg aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct ttcgcattat
    25981 ataataaact tacaaaaaca attcaaaagg agaacaatta tggaagtcat ttcaagtgtt
    26041 ctaaattggt tttctagcaa tattttgcag aatcccgcat ttttcgtagg tttattggtg
    26101 ttgataggat atgcactttt gaaaaaacct gcccatgacg ttttttcagg gtttgttaaa
    26161 gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac aacctttcgt
    26221 ccaatcttag cagctcttaa ctacaaattc caaattggtg cagcggttat cgacccttac
    26281 tttggacttg ctgcagcaaa caacaaaatt gcagcagagt ttccagattt tgttggaact
    26341 gcaactacag ctctattgat tggttttgga ataaatatct tgctcgtagc tcttcgaaag
    26401 attacgaagg taagaaccct ctttattact ggtcacatca tggtacaaca agctgcaaca
    26461 gtatctctta tggttctatt cttagtacca caattgcgca atgcttacgg tacagcagcg
    26521 attggtatca tctgtggact ttactgggca gttagttcaa atatgactgt tgaggcaact
    26581 caacgcttga ctggtggtgg cggatttgcg attggtcacc aacagcaatt tgcaatctgg
    26641 tttgtagata aagtagcagg acgctttggt aagaaagaag aaagtttaga caatcttaaa
    26701 ttacctaagt tcctctcaat cttccacgat acagttgttg catctgctac cttgatgctc
    26761 gtattcttcg gagccattct tttaatcttg ggtccagaca ttatgtctaa taaagaagtc
    26821 atcacttcag gaactctatt caatcctgct aaacaagatt tctttatgta cattatccaa
    26881 acagccttta ccttctcagt ttacttgttc gttttgatgc aaggtgtccg aatgttcgta
    26941 tctgagttga caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg ttcattccca
    27001 gcggttgacg ttgcagcttc ttatggattt ggttctccaa atgctgtcct gtcaggattt
    27061 atctttggtt tgattggtca attgattaca attgttttgc tcatcgtctt taaaaatccg
    27121 attcttatta ttacaggatt tgtaccagtg ttctttgaca atgcagccat tgcggtctac
    27181 gctgataaac gcggcggatg gaaagcggct gttatccttt cctttatatc aggtgtcctt
    27241 caagttgctc taggagctct ttgtgtggcc cttctcgatt tggcatctta tggtggctac
    27301 catggaaata tcgactttga attcccatgg cttggatttg gatatatctt caaatacctt
    27361 ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg ttattcctca acttcaattt
    27421 gccaaagcaa aagataaaga gaaatattac aacggtgaag ttcaagaaga agcttagtat
    27481 ctagaaaagg agaaataaaa tggttaaagt attagcagcg tgcggaaatg gaatgggttc
    27541 atcaatggtt atcaagatga aggttgaaaa tgctctccgt aagcttaatc aaacagattt
    27601 tacagtcaat tcatgcagtg tcggtgaagc taaaggttta gcagtaggat atgacatcgt
    27661 aatcgcttct cttcatttga ttcaagaatt ggaagggcga actaatggga agttaattgg
    27721 gcttgataac ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag cactacagta
    27781 aaaggttgga gggggctgga cagaaactga gagttatcgt ttctgtcctt ctccctcttt
    27841 aaataaagga ggcagatatg aatttaaaac aagctttaat tgacaacgac tcgatccgac
    27901 taggtttaga ggctaacgat tggaaagaag cagtcaaggt agcagtagat cccttgattg
    27961 aaagtggggc aattttgcca gagtattacg atgctatcat tgaatcgact gaagagtatg
    28021 ggccttacta tatcttgatg ccaggtatgg ctatgcccca cgctagacct gaagctggtg
    28081 tgcaaagtga tgccttttca ttaattacct tacaaaatcc tgttgtattt tcagatggga
    28141 aagaggtatc tgttttgttg gcactagcag caacaagttc aaaaattcac acaagtgtag
    28201 ccattccaca aattattgcc ctgtttgaat tagaagattc tattgcacgt ttacaggctt
    28261 gccagactaa agaagatgtc ttggctatga ttgaagaatc taaggatagc ccttatctcg
    28321 aaggattgga tttggaaagt tagaaagagg aataaagaaa tgacaaaaag aatacctaat
    28381 ttacaagttg cattagacca ttcagacttg caaggagcga ttaaagcagc tgtttctgtt
    28441 ggtcaggaag tagatattat cgaagctgga actgtttgct tgcttcaagt tggaagtgaa
    28501 ctggctgaag tcttgcgtag ccttttccca gataagatta ttgtggcaga cacaaaatgt
    28561 gctgatgctg gtggaacagt tgctaaaaat aatgcggttc gtggagcaga ctggatgact
    28621 tgtatctgtt gtgcaaccat ccctactatg gaagcagctc taaaggctat caagactgaa
    28681 cgaggagaac gaggcgaaat ccagatcgag ctttatggcg attggacttt tgaacaagct
    28741 cagctttggc tagatgcagg tatctcacaa gctatttatc accaatctcg tgatgctctt
    28801 cttgctggtg aaacttgggg tgaaaaagac cttaataagg ttaaaaaact cattgacatg
    28861 ggcttccgtg tatctgtaac aggtggtcta gatgtagata ctctcaaact ctttgaaggt
    28921 gttgatgtct ttacctttat cgcaggtcgt ggaattacag aggctgtgga tccagcagga
    28981 gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg ggtaaatcat ggtacgtcca
    29041 attggaattt atgaaaaggc aaccccaaca cactttactt ggctagaacg tttaaatttt
    29101 gccaaggagt taggctttga ttttatcgag atgtctattg acgaacgtga cgagcgttta
    29161 gcaagacttg actggagtaa ggaagaacgc ttggaagttg tcaaagaaat ctatgaaact
    29221 ggtgttcgta ttccttctat ctgtttttca ggccatcgtc gctacccatt gggatcaaaa
    29281 gattcagttc tagaggaaaa atctctagaa ctcatgaaaa aatgtatcga attagctcaa
    29341 gacttgggag ttcgtacgat tcaattagct ggttacgatg tttactatga ggaaaagtca
    29401 ccccagacac gccaacgttt tatcaaaaat ttgagaaaag cctgtgactg ggctgaagaa
    29461 gctcaggtgg tacttgctat tgaaattatg gatgatcctt tcatcagtag catcgaaaaa
    29521 tatttggcta tagaaaaaga gattgactct cccttcctct ttgtatatcc agatattggt
    29581 aatgtgtctg catggcataa tgatatctat agtgagtttt atcttggtca tcatgccatc
    29641 gcagctctcc atctcaagga tacttatgca gtgacagaaa gttcaaaggg ccagttccga
    29701 gatgtacctt tcgggcaagg ttgtgtcaaa tgggaagaag ctttcgatat tttaaaggaa
    29761 accaattata atggaccttt cctaatcgaa atgtggtctg aaaattgtga aacagtagaa
    29821 gaaacacgcg cagccattca agaggcgcaa gcttttctct atccactcat taagaaagca
    29881 ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt aaacgagtct gtgatgccaa
    29941 tcaatcattg ccaaaacatg gacttgtcaa atttacctgg gggaatgtat ctgaagttaa
    30001 tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg gattatgacg aattgacacc
    30061 tgaaaacatg gtagtgactg atctagatgg taagatccta gaaggggatt taagaccatc
    30121 ttccgacctc ccaactcatg tgcaattata taaggcttgg tcagaaattg gtagtgtggt
    30181 tcacacccat tcgacagaag ctgttggttg ggctcaggca ggtcgtgata ttcctttcta
    30241 cggaacaacc catgcagatt atttctacgg ttcaatccct tgcgcccgta gtttgaccaa
    30301 ggacgaagta gaagtggcct atgaaaaaga tactggcctg gttatcgtag aagagtttga
    30361 acatcgcgga cttaacccgg ttgaagtacc aggaattatt gtacgcaatc acggtccatt
    30421 cacctggggc aaaaatccag agaatgctgt ttatcactct gtcgtactag aggaagtatc
    30481 aaagatgaat cgctttacag aacaaatcaa tccaagagtt ggacctgctc cccagtacat
    30541 actagaaaaa cactaccaac gtaaacatgg accaaatgct tattatggtc aaaagtaaga
    30601 acgatgaagg aggagaaaaa gataaattta gctcctcttt ttacatttga tttttattga
    30661 gagtaaagtt ggaattgaag taattttaaa agatttttta gaaatagcgc ttgatatata
    30721 tatggtaaaa taaaaagaat tgctgtgata tcaatagatt tgggggattt tttaatatgg
    30781 tactggataa ggcaagttgt gatttgcttc aatatttgat ggatcaagaa acgtccaaaa
    30841 cgattatggc gatttcgaaa gatttgaaag agtcaagaag gaaaatttat tatcacattg
    30901 acaaaatcaa tgctgctctg ggtgacgagg cgcttcacat cattagtatt ccacgaattg
    30961 gtattcactt aacggaagag cagagagatg cttgttgtaa actattatcg gaagtagatt
    31021 cgtacgatta tatcatgagt gcgcatgaac gtatgatgat aatgttacta tggataggta
    31081 tttctaaaga acgtattacg attgaaaaat tgatagagtt aacagaggta tctaggaata
    31141 ctgttctcaa tgatttgaat agtattcgtt atcaactaac tttggaacaa tatcaggtga
    31201 tcttgcaagt gagcaagtca cagggatacc accttcatgc ccaccctctt aataaaattc
    31261 agtatcttca atcgcttcta tatcatattt ttatggaaga aaatgccact tttgtatcta
    31321 ttttagaaga taagatgaaa gagaggttag atgatgagtg tttgctttct gttgaaatga
    31381 accaattttt taaggaacag gttcctttag ttgaacaaga tttagggaag aaaataaacc
    31441 atcatgaaat aacttttatg ttgcaggttc taccttattt gctgttaagc tgtcataatg
    31501 ttgaacagta tcaagaaaga catcaggata tagagaaaga attttctttg ataagaaaaa
    31561 gaatagagta tcaggtgtct aagaaattag gagaacggtt gtttcaaaag tttgaaattt
    31621 ctttgtcagg acttgaagtt tctcttgtag ctgttctcct cctctcctat cgtaaagatt
    31681 tggatattca tgcagaaagt gatgattttc ggcaattaaa acttgcttta gaagaattta
    31741 tctggtattt tgaatcacaa atccgaatgg agattgagaa caaggatgat ttgttacgaa
    31801 atttgatgat ccactgtaaa gccttgttat ttagaaagac ttacggtatt ttttctaaaa
    31861 atcctctaac aaaacaaatt cgatccaagt atggagaatt atttttagtc actagaaaat
    31921 ctgcggaaat tttagaagga gcatggttta ttcggctaac agacgatgat attgcctatt
    31981 tgacgattca tattggagga tttttaaaat atacaccatc gtctcaaaaa aatatgaaaa
    32041 aagtttatct cgtttgtgat gaaggtgttg cggtttcgag acttttgctg aaacaatgca
    32101 aactttattt tccaaatgag caaattgaca ctgtatttac aacagaacaa tttaagagtg
    32161 tggaagatat tgcacaagtt gatgtagtga ttactactaa tgatgatttg gatagcagat
    32221 ttccgatttt aagggttaat cctatccttg aagcagaaga tattttgaaa atgctagact
    32281 atcttaaaca caatatattt cgtaataaga gcaaaagttt cagtgaaaat ctttctagtc
    32341 ttatttcgtc ttatattgta gacagcaagt tggctagtaa gttccaagaa gaggttcaaa
    32401 cacttataaa tcaagaaata gtagttcaag cttttttgga agatatttga aggacagtcc
    32461 aatgatgaac acaaacctgt gtttttcttg gtctttttta gtgttttgaa gggtggtata
    32521 ctaatctcaa agataacaat tatatccaaa ggaggcaaca tatgccaaac gtcaaagaaa
    32581 ttacaagaga gtcatggatt ttagccactt tcccagagtg gggaacatgg ttgaacgaag
    32641 aaatcgaaga agaagtcgta cctgaaggca actttgccat gtggtggcta ggcaactgtg
    32701 gtacttggat taagacacca gctggtgcta acgttgtcat ggacctttgg tcaaaccgtg
    32761 gaaaatcaac caaaaaagtg aaagatatgg ttcgtgggca ccaaatggca aatatggcag
    32821 gtgttcgtaa gttgcaacca aacttgcgtg ttcagccaat ggttatcgat ccatttgcta
    32881 tcaacgaact agactattac ttagtttcac acttccacag tgatcatatc gacccataca
    32941 cagctgcagc aattctcaac aatcctaagt tagagcatgt taagtttatc ggtccttacc
    33001 actgtggacg aatctgggaa ggatggggtg ttccaaaaga acgtatcatc gttgttaaac
    33061 caggtgacac tatcgaatta aaagatatga agattcatgc agtagaatca tttgaccgta
    33121 cttgcttggt aactctccca gtgaacggtg ctgatgagac aggcggtgaa cttgctggct
    33181 tggctgttac agatgaagaa atggctcaaa aggctgttaa ctatatcttt gaaacaccag
    33241 gtggaaccat ctatcatggt gcagattctc acttctcaaa ctattttgca aaacatggta
    33301 aagactttaa aattgatgtt gctttgaata actatggtga aaatccggta ggtatccaag
    33361 acaaaatgac atctatcgac cttcttcgta tggcagaaaa tctgcgtacc aaagtcatta
    33421 tcccagttca ctatgatatc tggtctaact tcatggcttc tactaatgag attctagaac
    33481 tttggaaaat gcgaaaagat cgcttgcaat acgatttcca tccatttatc tgggaagttg
    33541 gcggtaagta cacttatcct caagatcaac acttagtaga ataccatcat ccacgtggtt
    33601 ttgatgattg ttttgaacaa gactctaaca ttcaatttaa agctttgcta taatataaaa
    33661 atattctttg gaggttatcc gtatgttgca tgatacggat aattttcata taatagtaaa
    33721 atagaatgtg tgattcaata atcacctcaa atagaaagga aattctatgt caaatctatc
    33781 tgttaatgca attcgttttc taggtattga cgccattaat aaagccaact caggtcatcc
    33841 aggtgtggtt atgggagcgg ctccgatggc ttacagcctc tttacaaaac aacttcatat
    33901 caatccagct caaccaaact ggattaaccg cgaccgcttt attctttcag caggtcatgg
    33961 ttcaatgctc ctttatgctc ttcttcacct ttctggtttt gaagatgtca gcatggatga
    34021 gattaagagt ttccgtcaat ggggttcaaa aacaccaggt cacccagaat ttggtcatac
    34081 ggcagggatt gatgctacga caggtcctct agggcaaggt atttcaactg ctactggttt
    34141 tgcccaagca gaacgtttct tggcagccaa atataaccgt gaaggctaca atatctttga
    34201 ccactatact tacgttatct gtggagacgg agacttgatg gaaggtgtct caagcgaggc
    34261 agcttcatac gcaggtttgc aaaaacttga taagttggtt gttctttatg attcaaatga
    34321 tatcaacttg gatggtgaga caaaggattc ctttacagaa agtgttcgtg accgttacaa
    34381 tgcctacggt tggcatactg ccttggttga aaatggaaca gacttggaag ccatccatgc
    34441 tgctatcgaa acagcaaaag cttcaggcaa gccatctttg attgaagtga agacggttat
    34501 tggatacggt tctccaaaca aacaaggaac taatgctgta cacggcgccc ctcttggagc
    34561 agatgaaact gcatcaactc gtcaagccct cggttgggac tacgaaccat ttgaaattcc
    34621 agaacaagta tatgctgatt tcaaagaaca tgttgcagac cgtggcgcat cagcttatca
    34681 agcttggact aaattagttg cagattataa agaagctcat ccagaactgg ctgcagaagt
    34741 agaagccatc atcgacggac gtgatccagt cgaagtgact ccagcagact tcccagcttt
    34801 agaaaatggt ttttctcaag caactcgtaa ttcaagtcaa gatgccttga atgttgtggc
    34861 agctaaatta ccaacctttc taggtggatc agctgacctt gctcactcaa acatgactta
    34921 tatcaagacg gatggacttc aagacgatgc caatcgcttg aatcgtaaca ttcagtttgg
    34981 tgttcgtgaa tttgcaatgg gaacaatctt gaacgggatg gcccttcatg gtggacttcg
    35041 tgtatacggt ggaactttct tcgtcttctc tgactatgtg aaggcagctg tccgcttgtc
    35101 agccttacaa ggacttcctg tgacttatgt ctttacccat gattcaatcg cagttgggga
    35161 agatggtccg actcacgaac cagttgagca tttagcaggt cttcgtgcta tgccaaatct
    35221 aaatgttttc cgtccagcag atgcgcgtga aacgcaagca gcttggtacc ttgcagtgac
    35281 aagtgagaaa acaccaactg cccttgtctt gacacgtcaa aacttgactg ttgaagatgg
    35341 aacagacttc gacaaggttg ctaaaggtgc ttatgttgta tatgaaaatg cagccgactt
    35401 tgataccatc ttgattgcga caggttcaga ggttaatctt gctgtctcag ctgctaaaga
    35461 attggctagt caaggcgaaa aaatccgcgt agtcagcatg ccatctacag atgtctttga
    35521 taaacaagat gcagcttaca aggaagaaat tcttccaaat gcagtccgcc gtcgtgttgc
    35581 agtcgaaatg ggtgcaagtc aaaactggta caaatatgtt ggtctcgatg gtgccgttct
    35641 aggtattgat accttcggag cctctgcccc agcaccaaaa gtattggcag aatatggctt
    35701 tactgtagaa aatcttgtaa aaattgttcg aaacttgaaa taatcctaaa aatcagggcg
    35761 taagctctgg tttttcttac cagaaaagta aggtacaatc ttgtaaaagt agctgaaatt
    35821 tgatatagta gtcctatgta aaagacaaag gagaaaacaa tgaatccaaa tattactttt
    35881 ttaatcatgc ttgtaggtat gatggccttg atgttcttta tgcaacgttc tcaaaagaaa
    35941 caagctcaaa agcgtatgga aagcttaaat aaactacaaa aaggctatga agtgattaca
    36001 atcggtggac tttatggaac agtcgatgaa gtagatacgg agaagggaac aatagttctt
    36061 gacgtagatg gagtttactt gacttttgaa ctagctgcta tcaagacagt attaccgctg
    36121 aaagaaacag cttcactaga aggcgcaatt gaaaaataag acgggatcac gaactcccgt
    36181 ttttctataa aagaaaggaa atgggatgaa aaaattagtc tttgtctgtc tgggaaatat
    36241 ttgccgtagc cctatggccg agtttgttat gaaatcaatg acagataact acgaaatcca
    36301 aagtcgagca acttcctctt gggaacatgg caatccgatt cataagggga ctcagggaat
    36361 ttttcaacag tatgagattc tttatgacaa gaacaagaca tcgcttcaga ttagtaagga
    36421 agattttgaa gcctttgatt atattatcgg aatggacgct tcaaatattt ctgacttacg
    36481 tcagatgtgt ccagtagact gtcaagataa gatttactca ttttcatctg aaagtgttcc
    36541 agacccttgg tatacaggag attttgaaga aacctatcga cgtgttcaag agggctgtca
    36601 agcttggtta gaacgtttag aaaaggagag ttaaggtgga aaatcttacg aatttttacg
    36661 aaaagtatcg tgtctatctg actcgtccac gtttagagct tttggcagta gttaccattg
    36721 ttttctgtgc tgtactcgtc ttttttctaa atattccagg aaaaggtgtc ttaaaactcg
    36781 ataatggaac gattgtttat gatggcagtc ttgtccgtgg taaaatgaat ggtcaaggta
    36841 ccattacctt ccaaaatgga gaccaatata caggtggctt caacaatgga gccttcaacg
    36901 gaaaaggtac ctttcaatct aaagaaggct ggacctacga aggtgatttt gtaaatggtc
    36961 aggctgaagg aaaagggaaa ctaacaacag aacaagaagt cgtttatgaa ggaactttta
    37021 aacaaggcgt ttttcaacaa aaataaagcc tccttatcca aaggaggtat tattagaacc
    37081 acaaggtaag cgcttacctg taaatccctt tctttccaaa tccctcttcc aagcaagttt
    37141 gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac ctgataagaa
    37201 aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt ttatgaaact
    37261 gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac aaaggatatc
    37321 gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca ccagaggaaa
    37381 agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta gttgcccttg
    37441 aagaaatgcg taaattggat caagagcaag ttgactacat cgttgctaaa gcatcagtag
    37501 cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca ggacgtggtg
    37561 tatttgaaga taaagcaact aagaacttgt ttgcctgtga acacgtagta aacaacatgc
    37621 gtcacactaa gacagttggc gttatcgaag aagacgatgt aacaggattg actcttattg
    37681 ctgaaccagt tggtgttgtt tgtggtatta ctccaacaac aaacccaaca tcaacagcaa
    37741 tcttcaaatc attgatttca ttgaagacac gtaacccaat cgtctttgcc ttccatccat
    37801 cagcacaaga atcatctgct catgcagctc gtatcgtccg cgatgcagct atcgcagctg
    37861 gtgctcctga aaactgtgtg caatggatta ctcaaccatc tatggaagca acaagtgccc
    37921 ttatgaacca cgaaggtgtt gcgacaatcc ttgcaacagg tggtaatgcc atggttaagg
    37981 cggcttattc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt ccagcttatg
    38041 ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct aaatcatttg
    38101 ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa atttacgatg
    38161 aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa gaaaaagctc
    38221 ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct ggtgcaaaat
    38281 tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca ggatttacag
    38341 ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa aatgagccat
    38401 tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc cgtgaagatg
    38461 gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca gcagctatcc
    38521 acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct attcgtgtta
    38581 tctgtaactc accttctact tttggtggta ttggggacgt ttacaatgcc ttcttgccat
    38641 cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac gttagtgcca
    38701 ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa tggatgaaac
    38761 ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa tgtcgtgacg
    38821 ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc cttgatcgta
    38881 tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt gcggatgtag
    38941 aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt gccttcaaac
    39001 cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa gtaatgtggc
    39061 tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc atggatatcc
    39121 gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc gcgattccaa
    39181 ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat aaagcaaaca
    39241 accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc gtagatcctg
    39301 ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac gtattgactc
    39361 acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt ttagcacttc
    39421 aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgca gacttccact
    39481 cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc aatgccttcc
    39541 taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca atccacggtc
    39601 gtacaaatgc catcttgctt ccatacgtta tccgttacaa cggtacacgt ccagctaaga
    39661 cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa gatatcgcac
    39721 gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac gcaaaagctg
    39781 tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa ggaattgacg
    39841 aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa gaccaatgtt
    39901 caccagctaa cccacgtctt ccaatggtag accatatgca agaaatcatc gaagatgcat
    39961 actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt ctagaagcaa
    40021 gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa ggcatcctat
    40081 caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt tttgcccttt
    40141 ttgaaaaact agaatagaaa caaaatatat aatagattga aactagaata gtacacatct
    40201 gcttctaaaa cattgttaga attcgatttg actgtcctga tcgatttgtc ctgttcttat
    40261 ttcattttga tatataaaaa atat
//
LOCUS       DAVLBN010000013        39419 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLBN010000013 DAVLBN010000000
VERSION     DAVLBN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.013"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            47..394
                     /locus_tag="VXC24_000670"
     CDS             47..394
                     /locus_tag="VXC24_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0492820.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(511..1644)
                     /locus_tag="VXC24_000671"
                     /pseudo
     CDS             complement(511..1644)
                     /locus_tag="VXC24_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1709..1990
                     /locus_tag="VXC24_000672"
     CDS             1709..1990
                     /locus_tag="VXC24_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0492821.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2122..3066
                     /gene="manA"
                     /locus_tag="VXC24_000673"
     CDS             2122..3066
                     /gene="manA"
                     /locus_tag="VXC24_000673"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0492822.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(3106..4441)
                     /locus_tag="VXC24_000674"
                     /pseudo
     CDS             complement(3106..4441)
                     /locus_tag="VXC24_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            4669..5418
                     /locus_tag="VXC24_000675"
     CDS             4669..5418
                     /locus_tag="VXC24_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0492823.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(5438..5893)
                     /locus_tag="VXC24_000676"
     CDS             complement(5438..5893)
                     /locus_tag="VXC24_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0492824.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5913..7088)
                     /locus_tag="VXC24_000677"
     CDS             complement(5913..7088)
                     /locus_tag="VXC24_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0492825.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(7147..7992)
                     /locus_tag="VXC24_000678"
     CDS             complement(7147..7992)
                     /locus_tag="VXC24_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0492826.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            8117..8674
                     /locus_tag="VXC24_000679"
     CDS             8117..8674
                     /locus_tag="VXC24_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0492827.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            8693..9160
                     /locus_tag="VXC24_000680"
     CDS             8693..9160
                     /locus_tag="VXC24_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0492828.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            9249..9878
                     /gene="upp"
                     /locus_tag="VXC24_000681"
     CDS             9249..9878
                     /gene="upp"
                     /locus_tag="VXC24_000681"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0492829.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            10052..10642
                     /gene="clpP"
                     /locus_tag="VXC24_000682"
     CDS             10052..10642
                     /gene="clpP"
                     /locus_tag="VXC24_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0492830.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            10721..10969
                     /locus_tag="VXC24_000683"
     CDS             10721..10969
                     /locus_tag="VXC24_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0492831.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            11070..12230
                     /locus_tag="VXC24_000684"
     CDS             11070..12230
                     /locus_tag="VXC24_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0492832.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            12498..13367
                     /locus_tag="VXC24_000685"
     CDS             12498..13367
                     /locus_tag="VXC24_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0492833.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            13371..14327
                     /locus_tag="VXC24_000686"
     CDS             13371..14327
                     /locus_tag="VXC24_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0492834.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            14327..15091
                     /locus_tag="VXC24_000687"
     CDS             14327..15091
                     /locus_tag="VXC24_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492835.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            15091..15801
                     /locus_tag="VXC24_000688"
     CDS             15091..15801
                     /locus_tag="VXC24_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0492836.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            16160..16816
                     /locus_tag="VXC24_000689"
     CDS             16160..16816
                     /locus_tag="VXC24_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0492837.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            16924..18019
                     /gene="prfB"
                     /locus_tag="VXC24_000690"
     CDS             join(16924..16995,16997..18019)
                     /gene="prfB"
                     /locus_tag="VXC24_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0492838.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            18037..18729
                     /gene="ftsE"
                     /locus_tag="VXC24_000691"
     CDS             18037..18729
                     /gene="ftsE"
                     /locus_tag="VXC24_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0492839.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            18722..19648
                     /locus_tag="VXC24_000692"
     CDS             18722..19648
                     /locus_tag="VXC24_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0492840.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYYKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            19934..22114
                     /locus_tag="VXC24_000693"
     CDS             19934..22114
                     /locus_tag="VXC24_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0492841.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            22166..22981
                     /locus_tag="VXC24_000694"
     CDS             22166..22981
                     /locus_tag="VXC24_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0492842.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            23121..24464
                     /locus_tag="VXC24_000695"
     CDS             23121..24464
                     /locus_tag="VXC24_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0492843.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            24841..26031
                     /locus_tag="VXC24_000696"
     CDS             24841..26031
                     /locus_tag="VXC24_000696"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0492844.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            26584..27519
                     /locus_tag="VXC24_000697"
     CDS             26584..27519
                     /locus_tag="VXC24_000697"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0492845.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            27553..28590
                     /locus_tag="VXC24_000698"
     CDS             27553..28590
                     /locus_tag="VXC24_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0492846.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            28763..29368
                     /locus_tag="VXC24_000699"
     CDS             28763..29368
                     /locus_tag="VXC24_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0492847.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            29525..30055
                     /locus_tag="VXC24_000700"
     CDS             29525..30055
                     /locus_tag="VXC24_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0492848.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            30076..31161
                     /gene="rlmN"
                     /locus_tag="VXC24_000701"
     CDS             30076..31161
                     /gene="rlmN"
                     /locus_tag="VXC24_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0492849.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            31161..31643
                     /locus_tag="VXC24_000702"
     CDS             31161..31643
                     /locus_tag="VXC24_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0492850.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            31645..33186
                     /locus_tag="VXC24_000703"
     CDS             31645..33186
                     /locus_tag="VXC24_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0492851.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(33242..34045)
                     /locus_tag="VXC24_000704"
     CDS             complement(33242..34045)
                     /locus_tag="VXC24_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0492852.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34128..34349)
                     /locus_tag="VXC24_000705"
     CDS             complement(34128..34349)
                     /locus_tag="VXC24_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492853.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(34828..35025)
                     /locus_tag="VXC24_000706"
     CDS             complement(34828..35025)
                     /locus_tag="VXC24_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492854.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            35195..35467
                     /gene="rpsP"
                     /locus_tag="VXC24_000707"
     CDS             35195..35467
                     /gene="rpsP"
                     /locus_tag="VXC24_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0492855.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35487..35726
                     /locus_tag="VXC24_000708"
     CDS             35487..35726
                     /locus_tag="VXC24_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0492856.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            36303..37091
                     /locus_tag="VXC24_000709"
     CDS             36303..37091
                     /locus_tag="VXC24_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0492857.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            37122..37640
                     /gene="rimM"
                     /locus_tag="VXC24_000710"
     CDS             37122..37640
                     /gene="rimM"
                     /locus_tag="VXC24_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0492858.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            37630..38349
                     /gene="trmD"
                     /locus_tag="VXC24_000711"
     CDS             37630..38349
                     /gene="trmD"
                     /locus_tag="VXC24_000711"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0492859.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            38361..38699
                     /locus_tag="VXC24_000712"
     CDS             38361..38699
                     /locus_tag="VXC24_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492860.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(38730..39050)
                     /locus_tag="VXC24_000713"
     CDS             complement(38730..39050)
                     /locus_tag="VXC24_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492861.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            39148..39363
                     /locus_tag="VXC24_000714"
     CDS             39148..39363
                     /locus_tag="VXC24_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0492862.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
BASE COUNT        12066 a         7269 c         8512 g        11572 t
ORIGIN      
        1 actttaaaag atcggagcaa tccggtcttt ttatggagga gagtaaatga atttaaatca
       61 attagatatt atcgtttcaa atgttcccca agtctgtgct gacttggagc atatcttgga
      121 taaaaaggca gattatgctg atgatggttt tgctcagttt acgattggta gtcactgcct
      181 tatgttgtca caaaatcatt tggttccttt ggaaaacttt cagtcaggaa tcattattca
      241 tatcgagatt gaggatgtag accagaacta caaacggttg aacgagcttg gtataaaggt
      301 tttacacgga ccaactgtaa ccgattgggg aacagagtcc ttattagttc aaggacctgc
      361 tggtctagtg cttgattttt atcgtatgaa ataggtcgcg tagtcatttg acgttaacct
      421 tagctatttt taaaatagaa attgagaata tgaactattg aaagatcgga gcaatccggt
      481 ctttttatat aaagaaattg catataatac tcatctgctt tcaaaaagca ttctagtcca
      541 tctccgatta acgatggact ttatcacctc cttctccaat ccttgtatga catcttggag
      601 ttgattcatg acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat
      661 ctctttccac acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa
      721 gccaatatta gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac
      781 gagtaaaaaa taatcatatg gataagcttg tgaaagctct tctaaaaaga cgttcatcca
      841 ctcagtatta catccaccag ctcttaagaa aaatgattcg cctgtatagg catcaacagc
      901 tccataacaa tagcgaaatt ctcgtatata gtgactatgg atatgtggac ctactcctat
      961 tggagaccaa caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat
     1021 caagcgaacc ttacgaaaac gtctactggt tttaaatcgc tttcttttct tcttgaattg
     1081 agattttatt tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac
     1141 gtggcgtaat atttcgccaa ccatggcgct tcaacagttg atagaaggca tcacgtgtgt
     1201 aggaacgacc taactccttt ttataagcct gaaataaggc atcaattgta acaaattctc
     1261 ctgcctctgt agccttcaaa tgacgggcaa gaaaggcttt ctcttcctca actgtcatat
     1321 atgcatggtt acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat
     1381 attttttaca ttttgctaaa tcgttgtttg attacagtct aaaagctcta taatctcttt
     1441 ataagatttg cccatcagac gaaatataat agattgaaac tagaatagta cacctctact
     1501 tctaaaacat tgttagaaat cgatttgtcc tgttcttgtt tcattttact atagaacgat
     1561 ttgaaggcgt ttataatatt tagctgtacg agagtctttt aaaagtgttt tgatggtttg
     1621 gatttcttct ttagttgatt tcatattact attgtataat gctttttgat tttagtttag
     1681 tattatcgta gaaaatggac tcggtgctat ggatacaccg gatgagaatg gttatgtagc
     1741 agatgactat cggattactt acttagaggc ccacatcaag gccatgcgag atgccattta
     1801 ccaagatggg gttgacttgc ttggttatac gacttggagc tgtatcgatc cggtttcagc
     1861 tggcacaggg gaaatgaata agcgctatgg ctttatctat gtagatcgag ataatgtagg
     1921 aaatgggact ctcaaacgta gcaagaagaa gtccttctat tggtacatgt catttatagc
     1981 aatggtgtaa gcatcgagta gagcacattt gtttactatt tttataaaat cttctccctg
     2041 ctttataaga tgtaaaaaag agttcaaatg gaactctttt tttgctataa tgaggggaga
     2101 aaaatcagac aggagattaa gatgtcagaa ccattatttt tacaatcagt tatgcaagaa
     2161 aaaatctggg gtggtaccaa gttacgtgat gagtttggct acgacatccc aagtgaaaaa
     2221 gtcggagagt actgggctat ctcagctcat ctaaatggtg tttctaaagt tgccaatggt
     2281 cgttacgagg gaacagatct tgctactttg tatgcggaac accgtgaatt atttggcaat
     2341 cgtccagaac ctgtatttcc gcttttgacc aagatcctcg atgccaacga ctggctcagt
     2401 gtccaagttc acccagacga tgcttatgga ctcgagcatg aaggcgaact tggaaaaaca
     2461 gaatgttggt acatcattgc agcagatgaa ggttcagaga ttatctacgg tcacaatgcc
     2521 aagtcaaaag aagaactccg ccagcaaatc gaggataaga actgggatgc gctgttgaca
     2581 aaagtgccag ttaaagcagg agatttcttc tatgtaccaa gcggtaccat gcacgctatc
     2641 ggggcgggta tcttgattct tgaaacccag cagtctagcg ataccactta ccgtgtctat
     2701 gactttgacc gtaaggatga caagggcaat ttacgtgaac ttcaccttga aaaatctatc
     2761 gatgtcttga acattggtga acccgcaaat agccgtccag tgacaatcaa agcagatgat
     2821 ctacgttcca ctctccttgt atccaatgat ttcttcgcag tttacaaatg ggaaattact
     2881 ggaaaagtta actttgaaaa gacagctgac tacagcttgt tgagtgtctt ggctggtcaa
     2941 ggtcagctaa ctgttgacgg gaaaaattat ccaattcaaa aaggcagcca ctttatccta
     3001 ccaagtgatg ttgaagcttg gactctggaa gggcaaggtt tggaattgat tgttagccat
     3061 ccataaaaag aaagggcctg agttcactac tcaagtcctt tttgattaca taaattgggc
     3121 aatgaagacc acaatgatga tgattggaat gacgaaacga agaaacgaag aaggaagagc
     3181 cagacttgga acagtccttg tttccatgct ctttcatcga gatggagttc ctccattgca
     3241 agagcctttt taaagatata gcctgtaaaa agtgaaaggt agagagctcc aaatggcatg
     3301 aggagattgg aaaccaagaa gtccatagcg tcaaagaagg tcttaccaaa aatgtgaaca
     3361 tccgccatga caccgtaaga tagggctgaa ggaatgccaa agacaaaggt caaaattcct
     3421 aaaataacac tccatttggc acgtttgctg ttatcctggt tggtgatatt gcccacattg
     3481 atctccagca tcacgacaga agaagtgaca gtcgcaaaga gggagcggac gtagaaaatg
     3541 gttccaaaag gcatcttgtc aaagagttga ggcaagacga taaagagcag gctgggtccc
     3601 ccttcagact ggatattgaa gggggatcga gcttggaaaa tggctagacc tgccatgatg
     3661 gatatcgaga tattcatggc tacgatggag attcctgact ggactagatt ggttttcttg
     3721 tccaagtaag aagcataggt caacatgact gtaaccccta gtgagagggc aaagaaagat
     3781 tgtcccagag catagaggag accagcgcta gtcagttttg aaaagtctgg tttgaggaag
     3841 taaagaaccc cttccatggc atttggcaaa ctgagagagc gactgatgat aaaaacaaag
     3901 acgataaaga gcaggggcat catgactttc gaagctcttt caatcccttt ttgaacccca
     3961 cgtgatacaa tgaagatatt caataggata aaggccgctt gagctcctag ggcaatggct
     4021 ggatttgaaa tgattgaagt aaataactga gcataatcac ccgttccacc aagttggaac
     4081 aatttcccaa actcaatacc tagatagact agaatccatc ctccgataac actgtaaaaa
     4141 gataagagga taaagagggc aaaggcgcca atccaaccga taaagttgta cttgttattc
     4201 ttgcccagtt ttccaaaggt tttgatagcg gaaacgccag cactacggcc aagggcaaac
     4261 tcagccagca ggagagggaa accgattaaa atagtggaaa tgagaaagat tagtaaaaag
     4321 cctccaccgc cattagcagc agtcatgtag ggaaacttcc aaacggaacc aagcccgatg
     4381 gccagccagc agatgctaga ataaaaccaa gtttcgaccc ccattgtgat ttttctgaca
     4441 tagttaaact ctgatctcct ttttcaaaat aagaaaaagc tacttgagtt gtcaaatagc
     4501 cttctgtttg attgatagac ttgactatcc tatcatgttt tctaaggtct gtcaagaaaa
     4561 tcattttcaa gttttcacac ctttctcaaa aaagttaaaa aattttctca aaaacgcttg
     4621 actctgacct aaggggaggg gttatactat cattgtaagg aggaaatcat gtaccatata
     4681 aaagaagctg cgcagctttc aggtgtctct gtcaagaccc tgcatcacta tgacaagata
     4741 ggactcttgg tccccttaaa gtcggaaaac ggctatcgaa cctacagtca agaggatttg
     4801 gaacgccttc aggtcattct ttactacaaa tatctaggct tttctttaga gaaaatagca
     4861 gagctgttaa aggaagaaag gacagattta ttgccccatt tgactaggca gttggactat
     4921 ctaactcgcg aaaggcaaca tctggatacc ttgatttcca ccttgcaaaa aactattcaa
     4981 gaacaaaaag gagaaagaaa aatgaccatt gaggaaaaat tcacgggatt tagctatcaa
     5041 gacaatcaaa aataccacca agaagcggta gagaaatatg gtcaagaagt catgggacaa
     5101 gcgctcgaac gccaaaaagg tcacgaagac gaggctacgg ccgcctttaa ccaagtcttt
     5161 caaactttgg cacaaaatct tcaagttggt ttacctgcaa cagcaaccga aaaccaggag
     5221 caagcagcca agctcttgca agccattcgc acttatggat ttgactgctc tattgaggta
     5281 ttcggtcata tcggtaaagg ttacgtctat aacccagagt ttaaggaaaa cattgacaag
     5341 tttggttctg gaacagccca gtacacgtca gatgccattg cagcttacgt tcagacaaat
     5401 gcagaaaaaa taggctagga atttcctagc ctatttttta cttcaaatca taaagccagt
     5461 cgtcaccgtt tttgtagtaa aagaattcac tgagatcttc ttctagaaac acacgaagca
     5521 tatcagacat atcatcggtt gcaagtttta gatgagaaag attttcaaag tcctcccacc
     5581 aaactttccc ttcgtctgaa gactggagtt caccagtaaa gtgttctgtc ttgtaaaaaa
     5641 ggacgacata acgataatcc ttgtcgtcat accagttttt gataccacag agttggggtt
     5701 tggaaatgat cagaccagtt tcttctttca cttcacgaat gacagcatcg acaaaggatt
     5761 cgccacgttc aacatgacca ccaggaaaag taatgccagg ccagtcggga ctaactcggt
     5821 cttggaccag gaccttatct ccgtttttaa tcatacacat gttaacaaat tcgactgcct
     5881 ctcttctgtt cattcttcac aacctttaat ctttaatcat aatgcagact tcccgccacc
     5941 cagccggtac agagggcaga agtgatgtta aagccacccg tgtgggcatt gatatccata
     6001 acttcgcctg caaagtggag gccaggtacc agcttacttt caagggtttt aggattgatt
     6061 tccttgagac tgactccacc cttggtaaca aaggactttg caagggacat ttttccagtt
     6121 acaggaattt taagttcttt aatggactga acaagttgtt ctcgttcctt ttcagtcagc
     6181 tgtttgactt tttcaggata tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag
     6241 gtttttaaag cgtttttcaa ggatttttcc cgattttctt ctagaaatgt aaccaagtcc
     6301 ttctcagaaa gttgaggcaa aacatcgagt gagagaacct ccccaccttt gacaaagcta
     6361 gacatgcgta gggcagcagg acctgacaaa ccaaagtggg taaagagtaa atcatgagtg
     6421 atgacatgct taccataact tagggtcaca tcgtccagag aaatcccttg taaggcttta
     6481 tgtggaaaat ctgttaataa aggactttca gcagcctcaa gctcggtgat ggtatgctta
     6541 aaatggcgag caatctcgtg accaaaacca gtcgaaccag tcgaaggata agacttacca
     6601 cctgttgtga caatgagttt ctcacaagtg aaggtttgat ccgctgactt aaggacaaac
     6661 tggtcatcta cttttttaac agaaacgatt tctatttgag tagcaacttg accacctagt
     6721 tcggtgattt tcttttccaa agcttcgata atagtccgag acttgtcact ggctggaaag
     6781 acgcgtccgt ggtcttcgac cttaagttta acaccatttt ctgtaaaaaa gttgatgatg
     6841 tcatgattat cgaactggga gaaaacactg taaagaaagc gtccgtttcc aggaattcca
     6901 gctagcaggt tgtctaagct accattgttg gtcacattgc aacgtccccc accagtccca
     6961 gctaattttt ttccaagttt ccgatttttt tcgatgagga gggttttctg tccataaaag
     7021 ctactggaaa tcgtagccat cataccagca ggtcccccac cgatgacaat agtatcaaaa
     7081 tgtttcatag ctctattgta ccacaaaaaa acaagagatg atggtcacct cttgtcaaga
     7141 atgcaattaa tcaatttcat agcccatcag caaaccgcca tcttctgcat agaaactgca
     7201 gagaccagag gttggtagaa ttttaatatc cgcttgtggg aaggtttcac ggattcgctc
     7261 tgagagctgt tgacaacatt tttcgttatt gcgttgggcc atgacaatac ggccaccagc
     7321 atatccagct tttactaact catcataggc agcttgaact gatttctttg atccccttgc
     7381 tttttgtagc aattcgagag tcccagtttc actagctttt ccgaccatac gaatgttgag
     7441 aaggccaacg accgtaccga taagcttgct caaacggccg ttcttcacca agttatcgac
     7501 tttggctagg acaaagagca acttagtttt ttcttgatag gcggtgatag cttcaaccac
     7561 ttcttcaaaa gacaagccct ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac
     7621 ttcaccacca gcagataaac tatcaatcac atgaatctta gtgtcaggat ggtcttccag
     7681 ataaatattc tttgctagtt gagcactatt gtgactgcca gaaagggtac ctgtgatggt
     7741 tactaggaaa atgtttttgg caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca
     7801 agccgatttt gaagcttctg cagttgcata catggtttcc atcatttggt caatatcgag
     7861 actggcgtca tcaacaaaga cctgatcagc tacttgaatg gttaagggga cacttacaaa
     7921 ggttgtgtta atagctggtg ttggcagttg acgataatca caaccagagt cagcaataat
     7981 tttccaagtc atagaaattc tccatctttg tcagttatac attgacaaag gttctgtctt
     8041 tttttacaat tatatcatga aaacccttga aacaaaagca tcatccgtct gttgtgacaa
     8101 gtagaaagaa aatgttatgt ctgaacgtag aatctctgaa aagtctcttg aaaatctcag
     8161 aaaatcaaac caagaatcca atttattaac cagagaagcc attgaaacag ccctcttgca
     8221 actcttggaa aaaaaggagc tgaccaagat tagtatttct gaattggtca aacgtgcagg
     8281 tgtttcgcgt gcggcctttt atcgcaatta tgactccaaa gaggaaattt tagagagcgt
     8341 ctttaaacga actgtccaca atattatgga acagctgcat cattacgatt taaagacaga
     8401 cctttatttg gtttgggttc accttttccg ggaggccaga aaggaagcta gagtgattca
     8461 attggccttg gattaccatc tggaaaaaat ctttgtccaa gccatgcagg aatttctaga
     8521 aaaataccat gggaaatcaa aaggtgtcag ctcttatctt cattccttct ggagctcagc
     8581 catcgtctct gtccttctaa aatggatcaa ggatggcatg aaggtaccag ctgaaaagat
     8641 tgcagattta ggtttaccat tttttaaaaa atagagaaaa aggagaaaag agatgactga
     8701 aaaaagactg gcctgggatg agtattttgc agcccaagcc ctactaattg cgaatcgttc
     8761 cacttgtaaa cgtgctaaag tgggcgcgat tctggtaaaa gataataagg ttatttccac
     8821 tggttacaat ggttcggtgt cagggactga gcattgtatt gatcacgaat gtttggtcat
     8881 tgaaggccac tgtgttcgca cccttcacgc tgaggtcaat gctatccttc aaggtgctga
     8941 gcgtggtgtt cccaaaggct ttacagccta tgtaacccat tttccttgtc tcaactgtac
     9001 aaaacaattg cttcaggtcg gctgcaagcg cgtggtttat atcaaccagt accgaatgga
     9061 cgactacgcc caataccttt atcaagaaaa agggacagaa ttgacccatt taccacttga
     9121 gacagtacag acagctctta aagaggctga tctaatgtaa aaattatcaa aaataaatgg
     9181 cttagaaaga tttttaaacc gttttttggt ataataagaa gaataaattg aaagaaggaa
     9241 ttccaaaaat gggaaaaatt gaagttatta atcacccact gattcaacac aaattgtcaa
     9301 tcttgcgtcg tacagatact tctacaaaag cttttcgtga gctagtagat gagattgcaa
     9361 tgttgatggg gtatgaagta cttcgtgatc ttccactaga agatgtggaa atcgaaacac
     9421 caattacaaa aacagttcaa aaacaattgg caggtaagaa attggccatc gtcccaatct
     9481 tgcgtgcagg tatcgggatg gttgatggtc tcttgagctt ggttccagct gctaaagttg
     9541 gccacatcgg tatgtaccgt gatgaagaaa cacttcaacc agttgaatac ttggtgaaat
     9601 tgcctgagga cattgaccaa cgtcaaattt ttatagtaga cccaatgttg gcaacaggtg
     9661 gctcagcaat cttggctgtt gattctctta aaaaacgtgg cgcatcaaat atcaaatttg
     9721 tctgccttgt atctgctcca gagggtgtaa aagcccttca agaagctcat ccagatgtag
     9781 aaatctttac agcagccttg gatgaacgtt tgaacgaaca cggttatatc gttccaggtc
     9841 ttggagatgc tggagaccgc ttgttcggta caaaataaga tcgaaaagaa gaatgacttg
     9901 gaaaagtatt tccagtcacg aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga
     9961 gcaaaaattt gacctttttt gaccaagata ttataatagt cttatcttca gtcagttgac
    10021 caacaaaatt aaaactcaaa aggagaaatg aatgattcct gtagttattg aacaaacaag
    10081 ccgtggagaa cgttcttacg atatttactc acgtcttctc aaagaccgca tcattatgct
    10141 gacaggtccg gttgaagaca atatggctaa ctctgttatt gcccaattgc ttttcttgga
    10201 tgcccaagat agtacaaaag atatttacct ttatgtcaat acaccaggtg gttctgtttc
    10261 agctggtttg gcaatcgtag ataccatgaa ctttatcaag gcagatgtcc aaaccatcgt
    10321 tatgggaatg gctgcatcta tgggaacagt catcgcatca agtggagcaa aaggcaaacg
    10381 tttcatgctt ccaaatgctg aatacatgat tcaccaacca atgggcggta caggtggtgg
    10441 tacccaacaa actgatatgg ctatcgctgc agaacacttg ctcaaaactc gtaatacctt
    10501 ggaaaaaatc ttggctgaaa attcaggtca gtcaatggaa aaagtccatg cagatgcaga
    10561 acgtgataac tggatgagcg cccaggaaac acttgaatat ggctttattg atgaaattat
    10621 ggccaacaat tcattgaact aatgatgata gaaggcaaac tcgactgggt ttgctttttt
    10681 tggtataata gggagagatt tcttagaaag aggatttatc atgtttgaaa aagtcaatcg
    10741 ctctggcttg attatctatc tttactataa tcgtgatgcc aaaaaattgc aggattatgg
    10801 agatattacc tatcattcca agaaacatcg ttacttacaa ctctatgttc caactcaaga
    10861 agtggagcaa ttggtcggac gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg
    10921 tcatatccaa gagttggaaa caccctttgt gggcaatctt tatcgatagg aaaacgttat
    10981 catagaaaaa gttcaaggaa aacattgaca attttctgat aattcggtat attcttaaca
    11041 gactatttaa gaaataagga gacaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg
    11101 cgcttgcaag tgtagcactt cttgcagcct gtggagaagt gaagtctgga gcagtcaaca
    11161 ctgctggtaa ctcagtagag gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag
    11221 gttctttagc tgcatacgga acagctgaac aaaaaggtgc ccaattggct gttgatgaaa
    11281 tcaatgccgc aggtggtatc gatggaaaac aaatcgaagt aatcgataaa gataataagt
    11341 ctgaaacagc tgaggctgct tcagttacaa ctaaccttgt aacccaatct aaagtatcag
    11401 cagtcgtagg acctgcgaca tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag
    11461 caggtgttcc attgatctca ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt
    11521 acctctttat tggaactttc caagatagct tccaaggaaa aattatctca aactatgttt
    11581 ctgaaaaatt aaatgctaag aaagttgttc tttacactga caatgccagt gactatgcta
    11641 aagggattgc caaatctttc cgcgagtcat acaagggtga aatcgttgca gatgaaactt
    11701 tcgtagcagg tgacacagac ttccaagcag cccttacaaa aatgaaaggg agagactttg
    11761 atgctatcgt tgttcctggt tactataatg aggctggtaa gattgtaaac caagcgcgtg
    11821 gcatgggaat tgacaaacca atcgttggtg gtgatggatt caacggtgag gagtttgtac
    11881 aacaagcaac tgctgaaaaa gcatcaaaca tctactttat ctcaggcttc tcaactactg
    11941 tagaagtttc agctaaagct aaagccttcc ttgacgctta ccgtgctaag tacaatgaag
    12001 agccttcaac atttgcagcc ttggcttatg attcagttca ccttgtagca aacgcagcaa
    12061 aaggtgctaa aaattcaggt gaaatcaaga ataaccttgc taaaacaaaa gattttgaag
    12121 gtgtaactgg tcaaacaagc ttcgatgcag accacaacac agtcaaaact gcttacatga
    12181 tgaccatgaa caatggtaaa gttgaagcag cagaagttgt aaaaccataa tagaaaaatg
    12241 ttgaaatagg gaatgagcct ttgactcact ccctgtttcg atatttaata ctcttcgaaa
    12301 atctcttcaa actgcgtcaa cgtcgccttg gattatatat gtgactgact tcgtcagtct
    12361 tatctacaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta gtttgctctt
    12421 tgattttcat tgagtataag aacctatcaa aaagtgaggg aaaaccctcg gaattataaa
    12481 tagaaagagt gaatcttatg ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt
    12541 acgcgctgtt agccctagga tataccatgg tttacggaat tatcaagctc atcaacttcg
    12601 cccatggtga tatttatatg atgggagcct ttatcggtta tttcttgatc aattctttcc
    12661 aaatgaattt ctttgtagcg cttattgtag ctatgctagc gacagctatt cttggtgtcg
    12721 tgattgagtt tcttgcttac cgacctttgc gccactctac tcgtattgct gttttgatta
    12781 cggctattgg ggtttctttc ctattggagt atggaatggt ctatctggtt ggtgccaata
    12841 cccgtgcctt ccctcaagcg attcaaacag ttcgatatga tttgggagca attagcttaa
    12901 caaatgtgca gttaatgatt ttggccattt ccttgatttt gatgattttg ttacaagtca
    12961 ttgtccaaaa gactaagatg gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg
    13021 cacaattgat ggggatcaat gtaaaccgta cgattagctt taccttcgct ttgggttctg
    13081 ctcttgcggg tgcggctggt gttctgattg ctctttatta taactctctt gagcctttga
    13141 tgggggttac tccaggtctt aaatctttcg ttgccgcagt acttggtggt atcggaatta
    13201 ttcccggtgc ggctcttggt ggctttgtga ttggtctatt ggaaaccttt gcgacagcct
    13261 ttgagatgtc agatttccgt gatgccattg tttatggaat cttgttgttg atcttgattg
    13321 tccgcccagc tggtatcctt ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa
    13381 atttaaaagt taatattcta tggttactcc ttttgttagc tggctatagc ttgattagtg
    13441 tactggtttc agtcggagta cttaatctat tctatgtaca gattttacaa caaattggaa
    13501 ttaatattat tttggctgtt ggtctcaact taatcgttgg tttttcagga caattttcac
    13561 ttggtcatgc tggtttcatg gcgattggtg cctatgcagc agctattatt ggttctaaat
    13621 caccaaccta cggtgccttc tttggagcta tgcttgtagg ggctttgctt tcaggagcag
    13681 ttgccttact tgtcggcatt ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa
    13741 ctctgggtgt ttctgaaatt atccgtatct ttatcatcaa tggtggaagt cttacaaatg
    13801 gtgcggcagg tatcttaggg attcctaact ttacaacttg gcaaatggtt tacttctttg
    13861 tcgtgattac aaccattgca accttgaact tcttgcgtag cccaattggc cgttcaaccc
    13921 tctctgttcg tgaagatgaa atcgctgctg agtcagttgg ggttaatacg actaaaatta
    13981 aaatcatcgc ttttgtcttt ggtgccatta ctgcaagtat tgctgggtca cttcaggcag
    14041 gatttatcgg gtctgttgta ccgaaagatt acaccttcat caactcaatc aacgttttga
    14101 ttattgttgt atttggtgga ctcggttcca ttacaggtgc gattgtttcg gctattgttc
    14161 tgggaatttt gaatatgctt ctccaagatg ttgctagtgt gcgtatgatt atttacgctt
    14221 tggccttggt attggtaatg attttcagac caggtggact ccttggaacg tgggaactga
    14281 gcctatcacg tttctttaaa aaatctaaga aggaggaaca aaactaatgg cattacttga
    14341 agtaaaacag ttaaccaaac attttggtgg tctaacagct gttggagatg tgactcttga
    14401 attgaacgaa ggggaactgg ttggattaat cggtccaaac ggagctggga aaaccaccct
    14461 tttcaacctt ttgaccggtg tttatgaacc aagcgaggga acagtaaccc tagatggtca
    14521 ccttttgaat gggaaatcac cttataagat tgcctctttg ggacttggac gtactttcca
    14581 aaatatccgt ctctttaaag atttaacagt tttagataat gttttgattg cttttggaaa
    14641 ccatcacaaa cagcatgttt ttactagttt cttacgctta ccagcttttt acaagagtga
    14701 aaaagaatta aaggataaag ctttggaatt gttgaaaatc tttgatttag atggtgatgc
    14761 agagactctt gctaaaaatc tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc
    14821 ccttgctacg gaacctaaaa ttctcttctt agatgaacca gcagcaggta tgaacccaca
    14881 ggaaacagcc gaattgactg agttaattcg tcgtatcaaa gatgaattta agattacaat
    14941 catgttgatt gaacacgata tgaatctggt catggaagta acagaacgta tctacgtact
    15001 tgaatatggc cgtttaattg ctcaaggaac tccagacgaa attaagacca ataaacgcgt
    15061 tatcgaagct tatctaggag gtgaagccta atgtctatgt taaaagttga aaatctttct
    15121 gtgcattacg gtatgatcca agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa
    15181 gttgtttccc ttatcggtgc caacggtgca ggtaagacaa ctattcttcg caccttgtca
    15241 ggtttggttc gaccaagttc aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg
    15301 ccagctcaga aaatcgtggc aggtggtctt tcacaagttc cagaaggacg ccacgtcttt
    15361 cctggcttga ctgttatgga aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa
    15421 gaaaatcaag ctaacttgaa gaaggttttc tcacgctttc ctcgtcttga agaacggaag
    15481 aaccaagatg cagctactct ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct
    15541 cttatgtcaa caccaaaact tcttctttta gatgaaccat caatgggact tgccccaatc
    15601 ttcatccaag agatttttga tatcattcaa gatattcaga agcaaggaac aaccgtcctc
    15661 ttgattgaac aaaatgccaa taaagcactt gcaatctctg accgaggata tgtattggaa
    15721 acaggaaaaa tcgtcctatc aggaacagga aaagaactcg cttcatcaga agaagtcaga
    15781 aaagcatatc taggtggcta aaacaatcca gtggattgtt ttagtcggca gatgaagatt
    15841 acgaagtaat catcaatata gtccgggggc cctttttagt cggtggatga agattgcgaa
    15901 gcaatcatca aatccagagg attgttttag ccggtagatt gagattgcaa acaaatctgc
    15961 atctacattg aaagctgaat ttctaataat tgaaaaaatc gaatgaaacg tatcttacct
    16021 tcattcaggg agctcgattt tagagctctt tttgctagct tattcatact tttttgaatt
    16081 tcgaaaaaga aatgtaagcg tttgatagat ttacaaaaag attgtataat ggggataaga
    16141 atagaaaagg agaagtctca tggcagttaa agattttatg acccgcaagg tagtttatat
    16201 tagtccagat acaacagtat ctcatgcagc agatttgatg agagagcaag aattgcaccg
    16261 cttgcctgtt atcgaaaatg atcaattggt tggtttggtg actgagggaa ccattgcaca
    16321 agcaagtcca tctaaagcaa caagtctttc tatctatgag atgaattatc ttctgaataa
    16381 gacaaaagta aaagatgtca tgattcgcga tgttgtcact gtctcaggct atgctagtct
    16441 agaagatgca acttatctga tgttgaaaaa taagattggt attctccctg tcgtagataa
    16501 ccatcaagta tacggagtta ttactgaccg tgacgttttc caagcctttc ttgaaattgc
    16561 aggttatggc gaagaaggga ttcgtgtacg ctttgttaca gaagatgaag ttggtgttct
    16621 tggaaaaatt gtttctttga ttgtagaaga aaatttgaat atctcccata cagtcaatat
    16681 tccgcgtaag gatggtaagg tcattatcga agtgcaaatc gatggatcaa ttgatttacc
    16741 agccttgaaa gaaaaatttg aagcaaatgg tattcaagtg gaagaaatcg ctcgcacttc
    16801 agcaaaagtc ttgtaagaag ggaagcccaa aggcttcttt tttcatgaaa aggggattag
    16861 agaaaaagat ggaaagaaat gataaaatat gctataatga aataatgtaa aaaaggagta
    16921 tttatggaca tttcagtaat tcgtcagaaa attgacgcaa atcgtgaaaa attagcttct
    16981 ttcagggggt ctctttgacc tcgaagggct agaggaagag attgccatct tggaaaacaa
    17041 gatgacagaa cctgattttt ggaacgataa tattgcggcc caaaaaacgt cgcaagaatt
    17101 aaatgaatta aaaaacactt acaatacctt ccataagatg gaagagttgc aggatgaagt
    17161 cgaaatttta ttggattttt tggctgaaga cgagtcagtg catgatgaac tggtagcgca
    17221 gttagccgaa cttgataaga taatgaccag ctacgagatg actctactct tgtcagaacc
    17281 ttatgaccac aacaatgcca tcttggaaat ccatccaggt tctggtggta ctgaggcgca
    17341 ggactggggt gatatgttgc ttcgtatgta tactcgttat ggtaatgcta aaggctttaa
    17401 agtggaagtg ttggattacc aagcaggtga tgaggctggt attaagtcgg taactttatc
    17461 atttgaaggg cctaatgcct atggtctcct caagtcagaa atgggtgttc accgcttagt
    17521 gcgaatctca ccatttgact ctgccaaacg tcgccatacc tctttcacat ctgtagaagt
    17581 gatgccagaa ttggatgata ctattgaagt ggaaatccgt gaagatgata tcaagatgga
    17641 taccttccgt tcaggtggtg ccggtggaca aaacgtcaat aaggtttcaa caggtgtacg
    17701 tttaacccac attccaactg gaattgttgt ccaatcaaca gtggatcgta cccagtatgg
    17761 aaatagagat cgtgccatga agatgttgca ggctaagctc tatcaaatgg agcaagataa
    17821 gaaggctgcg gaggtagatt ctctcaaagg tgagaaaaag gagatcactt ggggaagcca
    17881 aatccgttct tatgtcttca cgccttatac tatggtaaaa gatcaccgaa ctagctttga
    17941 ggttgctcag gtagataagg ttatggatgg ggacctagat ggttttatcg atgcttatct
    18001 caagtggcga attagctaag atagaaagga actcacatgt caattattga aatgagagat
    18061 gtcgttaaaa aatacgacaa cggaacaact gctctacgcg gtgtttcggt tagcgttcaa
    18121 ccgggggaat ttgcttacat cgtaggacct tcaggagcag ggaagtcaac ttttattcgt
    18181 tctctgtatc gtgaagtaaa aatcgataaa ggaagcctat cagttgctgg ttttaatctg
    18241 gttaagatca aaaagaaaga tgtcccgctt ctacgtcgta gtgttggggt tgtcttccag
    18301 gattataaac tgttaccaaa gaaaactgtc tatgaaaata ttgcttacgc tatggaagta
    18361 atcggggaaa atcgccgtaa tatcaaaaga cgagtgatgg aagttttgga cttggttgga
    18421 ttgaagcata aggttcgttc ttttccaaat gaactctcag gtggggagca acagcgaatt
    18481 gcgattgcgc gtgcaattgt aaataatccc aaagtattga tagctgatga gccaacagga
    18541 aatctggatc cggataattc atgggaaatt atgaatctct tggaacggat taacctacaa
    18601 ggaacaacta ttttgatggc gactcataat agccagattg taaatacctt gcgccaccgt
    18661 gtcattgcca ttgaaaatgg ccgtgtcgtt cgtgacgaat caaaaggaga gtatggatac
    18721 gatgattagt agattttttc gccatttatt tgaagcctta aaaagtttga aacgaaatgg
    18781 ttggatgaca gtagctgctg tcagttcagt catgattact ttgaccttgg tggcaatatt
    18841 tgcatctgtt attttcaata cagcgaaact agctacagat attgaaaata atgtccgtgt
    18901 agtagtttat atccgaaagg atgtggaaga taatagtcag acaattgaaa aagaaggtca
    18961 aactgttaca aataatgact actacaaggt atatgattct ttgaagaaca tgtctacggt
    19021 taaaagtgtt accttttcaa gtaaagaaga acaatatgaa aaattaaccg agataatggg
    19081 agataactgg aaaatctttg aaggagatgc caatcctctc tatgatgcct atattgtaga
    19141 ggcaaacact ccaaatgatg taaaaactat agccgaagat gctaaaaaaa ttgaaggtgt
    19201 ctctgaggtt caagatggcg gtgccaatac agaaagactc ttcaagttag cttcatttat
    19261 ccgtgtttgg ggactaggga ttgctgcttt gttaattttt atcgcagttt ttttgatttc
    19321 aaataccatt cgtattacca ttatttcccg cagtcgcgaa attcaaatca tgcgcttggt
    19381 cggagctaaa aacagttata tccgtggacc gttcttgtta gaaggagcct ttatcggttt
    19441 attgggagct atcgcaccat ctgttttggt ctttattgtt tatcaaattg tttatcaatc
    19501 tgtcaacaaa tcgttggtag ggcaaaatct atccatgatt agtccagatt tatttagtcc
    19561 gttgatgatt gccctactat ttgtgattgg ggttttcatt ggttcattgg gatcaggaat
    19621 atccatgcgc cgattcttga agatttaggt aaaatagctg cttttatgag gagattgtaa
    19681 aatctccttt tttgctacaa gagtttttga aaagagatgc gcagaagaaa agagcttcca
    19741 aagaagtccc ccagagaaga cttcttgatg gctaatttga acttgaaatt tgactcacta
    19801 gaaatttttt agaaaaaagt gtaatttttt tataaaagcc tttacaaaaa aaattaaagt
    19861 ggtataatta aattatagaa ggtgcaaacg ttttcgtaaa acgtttgcct aaataaaaat
    19921 aaaggagatt tgaatgatga aagatacatt caaaaatgtc ttgtctttcg aattttggca
    19981 aaaattcggt aaggctttga tggtagttat cgcggttatg ccggctgctg gtttgatgat
    20041 ttcaatcggt aagtctatcg tgatgattaa cccaaccttt acaccacttg tcatcacagg
    20101 tggaattctt gagcaaatcg gttggggggt tatcggtaac cttcacattt tgtttgccct
    20161 agccattgga ggaagctggg ctaaagaacg tgctggtggt gctttcgccg ctggtcttgc
    20221 cttcattttg attaaccgta tcactggtac aatttttggt gtatcaggcg atatgttgaa
    20281 aaatccagat gctatggtaa ctactttctt tggtggttca atcaaagttg ctgattactt
    20341 tatcagtgtt cttgaagctc cagccttgaa catgggggta ttcgtaggga ttatctcagg
    20401 ttttgtaggg gcaactgctt acaacaaata ctacaacttc cgtaaacttc ctgatgcact
    20461 ttcattcttc aacgggaaac gtttcgtacc atttgtagtt attcttcgtt cagcaatcgc
    20521 tgcaattcta cttgctgctt tctggccagt agttcaaaca ggtatcaata acttcggtat
    20581 ctggattgcc aactcacaag aaactgctcc aattcttgca ccattcttgt atggtacttt
    20641 ggaacgtttg ctcttgccat ttggtcttca ccacatgttg actatcccaa tgaactacac
    20701 agctcttggt ggtacttatg acattttaac tggtgcagct aaaggtactc aagtattcgg
    20761 tcaagaccca ctatggcttg catgggtaac agaccttgta aaccttaaag gtactgatgc
    20821 tagtcaatat caacacttgt tagatacagt acatccagct cgtttcaaag ttggacaaat
    20881 gatcggttca ttcggtatct tgatgggtgt gattgttgct atctaccgta atgttgatgc
    20941 tgacaagaaa cataaataca aaggtatgat gattgcaaca gctcttgcaa cattcttgac
    21001 aggggttact gaaccaatcg aatacatgtt catgttcatc gcaacaccta tgtatcttgt
    21061 ttactcactt gttcaaggtg ctgccttcgc tatggctgac gtcgtaaacc tacgtatgca
    21121 ctcattcggt tcaatcgagt tcttgactcg tacacctatt gcaatcagtg ctggtattgg
    21181 tatggatatc gttaacttcg tttgggtaac tgttctcttt gctgtaatca tgtactttat
    21241 cgcaaacttc atgattcaaa aattcaacta cgcaactcca gggcgcaacg gaaactacga
    21301 aactgctgaa ggttcagaag aaaccagcag cgaagtgaaa gttgcagcag gctctcaagc
    21361 tgtaaacatt atcaaccttc ttggtggacg tgtaaacatc gttgatgttg atgcatgtat
    21421 gactcgtctt cgtgtaactg ttaaagatgc agataaagta ggaaatgcag agcaatggaa
    21481 agcagaagga gctatgggtc ttgtgatgaa aggacaaggg gttcaagcta tctacggtcc
    21541 aaaagctgac attttgaaat ctgatatcca agatatcctt gattcaggtg aaatcattcc
    21601 tgaaactctt ccaagccaaa tgactgaagc acaacaaaac actgttcact tcaaagatct
    21661 tactgaggaa gtttactcag tagcagacgg tcaagttgtt ggtttggaac aagtaaagga
    21721 tccagtattt gctcaaaaaa tgatgggtga tggatttgca gtagaacctg caaatggaaa
    21781 cattgtatct ccagtttcag gtactgtgtc aagcatcttc ccaacaaaac atgcttttgg
    21841 tattgtgacg gaagcaggtc ttgaagtatt ggttcacatt ggtttggaca cagtaagtct
    21901 tgaaggtaaa ccatttacag ttcatgttgc tgaaggacaa aaagttgcag caggagatct
    21961 ccttgtcaca gctgacttgg atgctatccg tgcagcagga cgtgaaactt caacagtagt
    22021 tgtcttcaca aatggtgatg caattaaatc agttaaatta gaaaaaacag gttctcttgc
    22081 agctaaaaca gcagttgcta aagtagaatt gtaatatact tgaggttgga agctgtattc
    22141 caacctctta ttttgggaga aaagaatgaa atttttaaca ctcaatactc acagttggat
    22201 ggagaaagaa gcagaggaaa aattccagat tttgcttgaa gatattcttg aaaaggacta
    22261 tgatttgatt tgtttccaag aaatcaatca ggagatgacc tcgtcagagg tggaggttaa
    22321 tgacctttat caagctttgc cagcagctga gcctattcac caagaccatt atgttagact
    22381 cttggttgaa aagttgttag agcaagggaa aaattactac tggacctggg cttataacca
    22441 tatcggctat aaccgctacc acgaaggtgt ggctatcttg tctaaaacac ctattgaagc
    22501 cagagaaatt ttggtttcag atgtggatga tccaacagac tatcatactc gccgtgttgc
    22561 cctagctgaa actgtagtcg atggcaagga gctagcagtt gccagtgttc atctctcttg
    22621 gtgggataaa ggtttccaag aagaatgggc acgatttgag gctgtcttga aaaaattgaa
    22681 caagccactt ttactagctg gagattttaa caacccagca ggtcaggaag gttaccaagc
    22741 tattttagct agtccattag gcttacaaga cgcatttgaa gttgctcaag agaaaagtgg
    22801 tagctatact gttccgcctg aaattgatgg ctggaaaggg aacactgaac cccttcgaat
    22861 cgattatgtc tttactacca aagagttagc ggtggaaaat ttacatgtcg tatttgatgg
    22921 taacaagagt ccacaagtga gtgatcacta tggcttgaat gctatgttaa actggaaata
    22981 ataactgaaa agaggttgga actataaaat tccagccttt tcttactaga gaagctactg
    23041 gaaatagcct aaataagtga gactactgta atggaataaa atatggtata attgataaga
    23101 tagatagaat cgaggatgtt atgtcattta cgaaatttca atttaaaaac tatattagag
    23161 aagccttgga ggagttaaaa tttacaactc caacagaggt gcaagacaag ttgattccta
    23221 ttgttttggc aggtcgtgac ctagtaggag aatcaaaaac aggttcaggt aagactcata
    23281 ctttcttgtt accgattttc cagcaattag atgaagctag cgatagtgta caagcagtga
    23341 ttactgcacc gagtcgtgag ttggctactc aaatttacca agtagcgcgt cagatttcag
    23401 ctcactcaga tgtcgaagtt cgtgtggtta attatgtggg tggtacggat aaggctcgcc
    23461 agattgagaa attggaaagc aatcagcctc atattgttat tggaacacca ggccgtatct
    23521 acgacttggt taaatctggt gatttagcta ttcataaagc caagacattt gttgttgatg
    23581 aagcagatat gaccttggat atgggattct tggaaattgt tgataagatt gctggcagtc
    23641 ttccaaaaga cttgcaattc atggtcttct cagcgactat cccacaaaaa ctgcaaccat
    23701 tcttgaaaaa atacttatca aatcctgtta tggagaaaat taagactaaa acggttattt
    23761 ctgacaccat tgataattgg ttgatttcga ccaagggaca tgataggaat gctcaaattt
    23821 accaattgac tcagttgatg cagccgtatt tggcaatgat ttttgttaac actaaaacgc
    23881 gtgctgatga attgcattca tatctgactg ctcaaggctt gaaggttgca aaaatccatg
    23941 gagatattgc ccctcgtgaa cgcaagcgaa tcatgaatca ggtgcaaaat ctggattttg
    24001 agtatattgt cgcaacagat ttagcagcgc gtgggattga cattgaaggt gtcagccatg
    24061 tcatcaatga tgccattccg caagacttat ctttttttgt tcaccgtgtt ggtcgtactg
    24121 gacgaaatgg cctaccaggt acagctatta ccctttatca gccaagtgat gactcggata
    24181 tccgtgagtt ggagaaattg ggaatcaagt ttagtcctaa gatggtcaaa gatggggaat
    24241 ttcaagatac ctatgaccgt gatcgtcgtg ccaaccgtga gaaaaaacaa gataaacttg
    24301 atatcgaaat gattggtttg gttaaaaaga aaaagaaaaa agtcaaaccg ggttataaga
    24361 agaaaattca atgggcggtt gatgaaaagc gccgtaaaac taagcgtgct gaaaatcgcg
    24421 ctcgcggtcg tgcagagcgt aaagctaaac gccaaacatt ttaatagaaa ttgttggagt
    24481 actgagctcc aactttttta tttatgagaa cgaactatct aaaccgaaac actacattaa
    24541 agactgcaaa ttgcgattaa aaatggtata atgataaagt tatatagtcc cgataagatg
    24601 gtaggtattt attacgaaga gttttcctat cagtagtttg caattcgcaa agaatgacgg
    24661 cttcgaggtt gctcgtcttt ctacggttgc cgccatactg cggtcaccct atgcgcctta
    24721 ctagcttcag aaataaaaaa gtatcgtttt tatttctgaa gctagtaact cttagataat
    24781 ggaaattcct atcagtactt tgtaactcta taacaatatt ttttaagggg ggacattttt
    24841 atgtcagaac gtaaattatt cacgtctgaa tctgtatctg aggggcatcc ggataagatt
    24901 gcagaccaaa tttcagatgc gattttggat gctattttag caaaggatcc agaggcgcac
    24961 gttgctgctg aaacagctgt atatactggt tctgtccacg tttttggtga aatttctaca
    25021 aatgcctatg tggatattaa ccgtgtggtt cgtgatacca ttgcagagat tggttatacc
    25081 aatacagaat atggattttc tgctgagacg gtgggagtac acccatcttt ggtggaacaa
    25141 tctcctgaca tcgctcaagg tgttaacgaa gccttggagg ttcgtggaaa tgctgatcaa
    25201 gatccactgg acttgattgg agcaggtgac caagggctca tgtttggatt tgcagtagat
    25261 gaaacagaag agctcatgcc attgccaatt gcactcagtc ataaattggt tcgtcgtctg
    25321 gcagaacttc gtaagtctgg agaaattagc tatctccgtc cagatgcaaa atcacaagtt
    25381 acagttgagt acgatgaaaa tgaccgtccg gtacgtgtag atacagtcgt tatttctact
    25441 cagcatgatc cagaggccac taatgaacaa atccatcaag atgtgattaa caaggtcatc
    25501 aaagaagtta ttccatcttc ttatcttgat gataagacaa aattctttat caatccgaca
    25561 ggtcgttttg taatcggtgg tcctcaaggg gactcaggtt tgactggtcg taagattatt
    25621 gtagatactt atggtggcta ctctcgtcat ggtggtggtg ccttctctgg taaagatgcg
    25681 actaaggtgg atcgttcagc ctcttatgcg gctcgctata ttgccaagaa tatcgttgca
    25741 gcaggccttg ctaagaaggc agaagtgcag ttggcctatg ctatcggtgt tgcgcaacct
    25801 gtttctgttc gtatcgatac tttcggtaca ggaacagtag ctgaaagtca acttgaaaaa
    25861 gcggctcgtc aaatctttga ccttcgccct gcagggatta tccaaatgct ggacctcaag
    25921 cgtccaattt accgtcaaac atcggcttac ggtcacatgg gacgtacaga tattgatctt
    25981 ccatgggaac gtttggataa ggtagatgct ttgaaagaag cagtaaaata agattttaag
    26041 aggggaacgt cctctctttt ttatagtttt taactatact gggatactgt tctgaaaatc
    26101 cattttgcga aagtagagat ttacatgtat agtagattga aactagaata gtacacctca
    26161 acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttctc ctgttcttgt
    26221 ttcattttac tatatttctt taaaaatgat aaaggttgag atttctcctc gtaatagata
    26281 atcatgggga tatttcaatc caaagtttta ttcgttatca cttgactatt gcaaggtttt
    26341 ctagagcaac agagtcatgg aatggactca tggttgagat ttctccttgt tgcttggact
    26401 tcattcaaaa gtctgttacc caagccttgt tcaaacttcc aatacactag ctgtttccat
    26461 agcatgactt ctgtactaga ctttcttttc cgaataaata gatagaacca cagaatctag
    26521 taaacctaga attaaaatta tggtataata ttagcaataa aagaaatctg gaggattaga
    26581 atcatggtat caacgaaaac acaaattgct ggttttgagt ttgacaattg cttgatgaat
    26641 gcagcaggtg tggcttgtat gacgatagag gagttagaag aggtcaaaaa ctcagcggca
    26701 ggaacctttg ttactaagac agcgaccttg gacttccgtc aggggaatcc tgagccacgc
    26761 taccaagatg ttccacttgg ttccatcaac tctatgggct tgccaaataa tggcttagac
    26821 tattatttgg attatctttt agatttgcag gaaaaagagt cgaaccgaac tttcttctta
    26881 tctctggtcg gcatgtctcc agaggaaacc catactattt tgaaaaaagt ccaagagagt
    26941 gattttcgtg gtctgactga gctaaatctt tcctgtccaa atgttccagg taaacctcag
    27001 attgcctatg attttgagac aacagaccgg attttggcag aagtgtttgc ttacttcacc
    27061 aaacctcttg gaattaaatt gccaccttat tttgatattg ttcactttga ccaagcggca
    27121 gctattttca acaaatatcc gctcaagttt gtcaactgcg ttaactctat cggaaacggc
    27181 ctctatatag aagacgaatc tgtcgttatt cggcctaaga atggttttgg tggaattggt
    27241 ggagaataca tcaaaccgac tgctctagcc aatgttcacg ccttttatca acgtttaaat
    27301 cctcaaatcc aaattatcgg aacaggtggc gttctgactg gtcgagatgc ctttgaacac
    27361 atcctctgtg gagcaagtat ggtgcaggtg ggaacgaccc ttcacaaaga aggcgtcagt
    27421 gcttttgacc gcattaccaa tgaactgaaa gcaatcatgg tggaaaaagg ctacgagagc
    27481 ttagaagatt tccgtgggaa attgcgctat attgactaaa ttaaatcgaa aaatcagaag
    27541 aaagaaggga cgatgctagc cattgaagaa agtcagaagt tgactttatc aaatttaccg
    27601 agcctgagcc tatttacagg gacagatcag ggtcagtttg aagtgatgaa gagtcaaatg
    27661 ttgaaacaga ttgggtatga ttctgctgac ctcaactttg cctactttga tatgaaagaa
    27721 gtagtttaca aggatgtgga actggagttg gtcagccttc ctttctttgc ggatgagaaa
    27781 atcgtgatat tagattattt tatggatatc acgactgcta agaaacgctt tttgacagat
    27841 gatgagctta agtcatttga ggaatacctt gacaatcctt ctccaacaac caagttgata
    27901 atctttgcag aaggaaagct ggatagcaaa agacggttag tcaaattact taagcgtgat
    27961 gccaaggtct tcgatgcagt agaagtaaaa gaacaagaat tgcgccagta tttccaaaag
    28021 tggagtcaga aacaaggtct gcagtttacc aatcattctt ttgaaaatct cctcatcaag
    28081 tcggggtttc aatttagcga aatccagaaa aatcttctct ttttacagtc ctataaggcg
    28141 aattctgtta tcgaggaaga ggatattgtt aacgcaattc ccaagacctt gcaggacaat
    28201 atttttgatt taactcagtt tattctgact aaaaagatgg atcaggcgcg cgatttagtg
    28261 agagacttga ccttgcaagg ggaagatgaa atcaaactga ttgcagtcat gctgggacaa
    28321 tttcggactt ttactcaggt gaagattttg gcggagtctg gccaaacaga atcgcagatt
    28381 gcaagtagtt taggtagtta tctgggacgt aacccaaatc cttatcaaat caagtttgca
    28441 ttaagagatt cgagaggact ttctttgagc tttctgaagc aagctatttc ctatttgatt
    28501 gagacagact atcagattaa gacaggtctt tatgaaaaag gtttcctttt tgaaaaggca
    28561 ctcttacaga ttgctagtca ggtcaattga catttgttga aactacaacc cgcgtcagga
    28621 ttatcttgtc gtgggtttct tgctgatttg cttattttat tagaaagtat atcagtgatt
    28681 tccttatcta taagcaaaaa acttgaaaaa agtgaatgtt tgcgttatca ttttcatata
    28741 gaaagaaaaa gaggtattac agatggctat tatcttacca gaacttccat atgcatacga
    28801 cgctttggaa ccatacatcg atgcggaaac aatgcatttg caccatgaca aacaccatca
    28861 aacttatgtc aacaatgcca atgcagcttt agaaaaacac cctgaaatcg gtgaagacct
    28921 tgaagccttg cttgctgatg tagaatctat cccagctgat atccgtcaag cacttatcaa
    28981 caatggtggc ggacacttga accacgctct tttctgggaa ttgatgactc ccgagaaaac
    29041 agctccttca gcagaactgg cagcagcaat cgatgcaaca tttggttcat ttgaagaatt
    29101 ccaagcagcc ttcactgcag cagcaacaac tcgttttggt tcaggttggg catggttggt
    29161 tgtcaacaaa gaagggaaac ttgaagtgac ttcaacagca aaccaagaca caccaatctc
    29221 agaaggtaaa aaaccaatct tgggcttgga cgtttgggaa catgcttact acgtgaaata
    29281 ccgcaacgtg cgtcctgact acatcaaagc tttcttttca gtaatcaact ggaataaagt
    29341 agatgaattg tacgcagctg ctaaataatg atagttggag ggaagaattg ttcttctctt
    29401 ttttaggtta taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa
    29461 acgtgctaac tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat
    29521 atctatgcga aaagaaattg cacctgaatt atacaattat aacaagtttc ctggtccgga
    29581 gttccattta cacggggaca aggtcgaaac ggaagggata gctttttcct tggttgaaaa
    29641 tatcaaggat gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa
    29701 gtttgattat atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa
    29761 ggatgaccga acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga
    29821 gtattgtagt tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc
    29881 atttgacaag aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc
    29941 gactcaaact aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca
    30001 gcattctcag aaagaggaca agggacaacg tcattttgtc attcgtcaga agtgagtaga
    30061 gaataaggag aagaaatgaa accctcaatt catagtttgg tacatcaaac catgcaggaa
    30121 tgggtattgg agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac
    30181 cgtaaacgtg tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag
    30241 ctcaatgacc agtttgtggt caatcccttg aaacaacgta ttgtgcaaga gtctgctgat
    30301 ggtacagtca aatatctctt tgaattgccc gacggtatgt taattgagac tgtactcatg
    30361 cgtcaacact atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt
    30421 accttctgtg cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta
    30481 gcgcaaatca tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc
    30541 catatcgttg tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc
    30601 gtttgtacta tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacgatttca
    30661 acctcaggtt tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt
    30721 gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa aattaaccgt
    30781 gcctttccga ttgaaaaact ctttgctgct attgaatact atattgagac aacaaaccgt
    30841 cgtgtaacct ttgaatatat catgcttaat gaagtcaacg acggtgtaga acaagccttg
    30901 gaattggctg aattgctcaa gaacatcaag aaattgtctt atgtaaactt gattccttat
    30961 aacccagtta gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc
    31021 tatgatacgc ttaagaaaaa aggggtcaac tgtgtggttc gtcaagagca tggtacagat
    31081 attgacgcag cttgtggaca attgcgctct aacacaatga aacgtgaccg ccagaaggca
    31141 gtcgcagcgg taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag
    31201 tcattttcta tagcatttgc attgtctgtt tttgctttac tcctcaagaa caatctaccg
    31261 tgggagtggg aactccaggt attcagcatc ttggacgcct ggtttttctt ttgactcctt
    31321 tcaattctct ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt
    31381 tacaaaatat cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat
    31441 ttccaaattt gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa
    31501 tcgagtgtac gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg
    31561 atgatttgtg gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac
    31621 ataaaaacaa ggtaaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt
    31681 tttggtgacc gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg agaacatatc
    31741 ggcctggtcg gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa
    31801 atgctgccag atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat
    31861 cagcactctg tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat
    31921 gagcttttca aagctgaagc tcgtatcaat gacctctata tgaaaatggc tgaagacggc
    31981 gcggatgttg atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt
    32041 gatttctata ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac
    32101 tttgggatgg atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg
    32161 gcaaaacttc tccttgaaaa gcctgatatt ttgctgttgg acgagccgac caactacttg
    32221 gatgctgagc atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt
    32281 cttatttcgc acgatattcc attcctcaat gacgttatta atattgtcta tcatgtggaa
    32341 aatcaacagc tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg
    32401 aagaaatctc agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag
    32461 gactttgtgg ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa
    32521 aagaaattgg ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt
    32581 gatttcaaac cagctcgtac accagggcgc tttatcttcc aagccaagaa cttgcaaatt
    32641 ggttacgacc gtcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt
    32701 gcgattattg gtgctaatgg tattggaaaa acaactctct tgaagagtct cttaggcatt
    32761 atctcgccaa tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag
    32821 caggaagtag aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct
    32881 gcccttaatc aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat
    32941 attgaaagcc agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc
    33001 ttgatgaatc gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg
    33061 gatgcaaagg atgagctcaa acgcgctctc aaagaataca ggggatctat ccttatggtc
    33121 tgccacgagc cagactttta tgaaggttgg atagaccaaa tatgggattt taataattta
    33181 acttaagaat gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt
    33241 tttaagattt aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag
    33301 ttggcttgtc tttttcatct ttttcggctt tagcaatctt atccacaaca tccataccgt
    33361 caatcacttg accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt
    33421 aggcttcgat aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag
    33481 agttttggtt gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag
    33541 caagagcacc acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt
    33601 tgtctttagt cttatccttg tcatgccata tggactgacc acctgtaccg tccccttttg
    33661 gatctccagt ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt
    33721 agccttcttt ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga
    33781 gtttaatgcg aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa
    33841 cttccttaga tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct
    33901 tggcagattg ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat
    33961 catcaccacg cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta
    34021 aaagaagggt tgctagtttt ttcattctga tcctctcaaa aattcattta taccattgta
    34081 ccctaaaagg aagtggattt caaatattag tagtttacag aactggctta gataatagtt
    34141 gggatttcat catcatcttg aaaatcttca acttcttcaa cttcttcccc agtaaatggt
    34201 ttctgaaaag aacttagtat aaaacgggca attggttcaa caattaggaa atttagagga
    34261 agagctgcaa taaagtttac gaaccaggcg cttagatagg tattgggtgt gatagcaatg
    34321 ccattgtaaa aaagtccata gaaggacatg aaagtgacca gctaattctt cttctgaaaa
    34381 atgctcatga agggcttgat ccaggtcgca agatttcatt ttagaaagtc cagtaactcc
    34441 cttcttcttc aggatattct ttttcatggt attatttaga tggtcaagtg agtcaaaaga
    34501 agtttcgaca agagcatacc ctttttctac cagagttttt agatgtttag gggcatcaat
    34561 accataagtg tactcaaagt attttggaaa ccagatctta agaaagctcg taaagctagc
    34621 cagttctcta aacgctaaga actagctaca acacagcatt tacaacactt catggttcac
    34681 accatggggt gttttttaat gattttaagc aaaattcaca cttaattgaa agttatttaa
    34741 attagatgaa aatttatttt ttgaaaaagt gggaaaacat tgattctaag cgaattttga
    34801 atcatattcg aatgggagtt tttaaaatca tgtttcagtg gtaaaagtac caaactggat
    34861 tctccatagt aaaatgatat ctcctgctag tgaatcatct gctaataagt ccatatttcg
    34921 cttgggactt agaagccaag tatccaactc tcgttcaggc gatatgaagg gtttgacttg
    34981 gtgttcttta taaaattttt ctaaaatagt attcacggat agcatctttc aaacatttat
    35041 ttcctattct aacaaatttc taaatgcttt aagaaattta tagtctgtca agtttttttc
    35101 ttgacacctg ccagaaatct gctataatag aacatgtgct aaatagctca gctatttcac
    35161 cgaaataaaa aattaaagaa atgagacttt aaaaatggca gttaaaatcc gtttgactcg
    35221 tatgggttct aagaaaaaac ctttctaccg tatcaacgta gcagattcac gttcaccacg
    35281 tgacggacgt ttcatcgaaa cagttggaac ttacaaccca cttgttgctg aaaaccaagt
    35341 aactttgaaa gaagaccgcg ttcttgcatg gttggctaat ggagctcaac cttcagacac
    35401 agtacgtaac atcctttcaa aagaaggcgt attgaaaaaa ttccacgatt ctaaattctc
    35461 aaaataagtt taaagtaggt tgacagatgg atacgattga aaatctcatt attgcgattg
    35521 tgaaaccctt aatttcacaa ccagatgcct taactatcaa gattgaggat acaccagaat
    35581 ttttggaata tcatttgaat cttgatcaaa gcgatgtggg tcgtgtaatc ggtcgtaagg
    35641 gtcgcactat ttctgcgata agaacgattg tctactctgt cccaactgaa tacaaaaaag
    35701 taagaatcgt tattgacgaa aaataagaag ggcgggacgg atgtctcgct tttttgtgtg
    35761 gaatagaaga tatagtaaaa tgaaataata acaggacaaa tcgatcagga cagtcaaatc
    35821 gatttctaac aatgttttag aagtaaaggt gtactattct agtttcaata tactataaaa
    35881 gattgaacgt ttaggcaatt ccaagactac ttaatcgaac attaacagca gtctcggact
    35941 gatgaaggtc tttttatgaa gttagtggag gaagtcggag aagtagccga ggttttgaat
    36001 aggcgctctg gtcgaaaaga agggatagga ttcgaacgag gaacttgcca gagaactggc
    36061 tgatatcatt tactacaccg tcgcaatcgt agctattaat catattgacc ttaccaagac
    36121 tgtctttgag aaagacaaaa ccgcagccgt taattaccaa cataaacata atttggaagg
    36181 attattgaag ggaaagtaga gatattgtcc ccttcctcca acttgagaaa atccttggaa
    36241 cgtgataaaa taaaggataa ggatttttaa taattcatta tatagaatca gtggatttct
    36301 ttatgaagag gtttgaagta tctacagaaa ttggtagcct ctctgttact tatcaaaagc
    36361 aaaagaaagt gctagtttgt ctaaacggag caggtttgct accaagttat gaaaattttt
    36421 cacttatact tgaaaaacct cctcctacaa ttggttattt gacaattgat tttccgaaca
    36481 caggtaggag tccgattcat gaccaagctg gaaaaaatct agataatctt gcagatgcgg
    36541 tttatgaagt acttgaagaa ttaggaattt ctgaatatat actttgtgca catagttgga
    36601 gtggaatttt agcttgcaaa ttactcgaga aaccaattaa gcgtcagact ttagtagcaa
    36661 ttgaaccgac aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct tatccagaaa
    36721 tggaagagca gatgaggctg attgacgagt gtggtcctga actttatttt aagaacttaa
    36781 ctcaagcaac atttagtcct gaaacgaata aaaaaatctg ggaattaatg caagaaaaag
    36841 gcttagagtt ggaaaatcaa gatccagaat ttcagatatc tggagagatt actgaggaag
    36901 attttgagga tgtatctata gaagctcata ttcctgtatt tgttttttgt cagccttata
    36961 gagaaaaaga gtacagagaa tcagaatatt ggacttccaa tactaaactc attttaggag
    37021 ggaatcacca ttatttacaa tggtcagaat cggaaaaaat tgcggctatt attcgagaat
    37081 tgttagaata agatggaaaa aaggagatta caggagacaa gatgaactac tttaatgttg
    37141 ggaaaatcgt taatacgcag ggattacagg gtgagatgcg agtcttgtct gtgacggatt
    37201 ttgcagaaga acggtttaaa aaaggagctg agctggcttt gtttgatgaa aaagatcagt
    37261 ttgtccaaac agtgaccatc gctagccacc gtaaacagaa gaactttgac attattaaat
    37321 tcaaagatat gtaccatatc aatactatcg aaaagtacaa gggatacagt ctcaaggtcg
    37381 ctgaggaaga tttgaatgac ctagacgatg gtgaatttta ctatcacgag attatcggtt
    37441 tggaagtcta tgagggtgat agcttggttg gaaccatcaa ggaaatcctg caaccaggtg
    37501 ctaatgatgt ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta ccttatatcc
    37561 caccagtggt tctcaatgtt gatattccaa ataaacgggt cgatgtggaa atcttagaag
    37621 ggttagacga tgaagattga tattttaacc ctctttccag agatgttttc tccactggag
    37681 cactcaatcg ttggaaaggc tcgagaaaaa gggctcttgg atatccagta tcataatttt
    37741 cgagaaaatg ctgaaaaggc ccgtcatgta gatgatgagc cctacggagg cggtcagggc
    37801 atgttgctca gagtacaacc tattttcgat tcctttgatg ctattgaaaa gaaaaatccg
    37861 cgcgttattc tcctcgatcc tgctggaaag cagtttgatc aggcttatgc tgaagatttg
    37921 gctcaagagg aagagctaat ctttatctgt gggcactatg agggttatga tgagcgcatt
    37981 aagaccttgg taacagatga gatttcccta ggcgactatg tcctcactgg tggagaattg
    38041 gcagctatga ccatgattga tgctacagtt cgcctgattc cagaagtgat tggcaaggag
    38101 tctagccacc aagatgatag tttttcttca ggtcttttag aatatcctca gtacacacgt
    38161 ccttatgatt atcgaggcat ggtcgtgcca gatgtattga tgagtggcca ccatgaaaag
    38221 attcgtcagt ggcgattgta cgagagttta aagaaaacct acgagcgcag accggattta
    38281 cttgaacatt atcaactgac agtagaagaa gaaaaaatgc tggcagaaat caaagaaaac
    38341 aaagaataaa ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt gctgaattta
    38401 atccagataa gatttaccaa gccatcttga aggcagccca aactgtttat gttttgacag
    38461 atgatttgcg tcaaaatctt gctcaagtca ctaagaaggt agttttggat ttacaagaag
    38521 ccaaggtgga acgtgcgact atcagtatga ttcaatctat ggttgaacat cgtttattgg
    38581 gcgcaggtta cattaccatt gcagaacact acatttccta tcgtttacaa cgtgacttgg
    38641 aaagaagtgg ttatggagat catatcgcag ttcatttaca ttttgaacaa attcgctaag
    38701 aaaaaagagt gggatgaagc aactacatct cactctttct taaatctatt tttttgggct
    38761 gtttggacag ttgaggggac aaatcgcagg cgttgaatat cgcttatacg gataatccgg
    38821 ctcacatttt tggaaaaatt tttcacgata atttgctggc cttgctgatc atatttgatg
    38881 atgtcacctg taaagcttgt ctcagataag ataaggtgaa cagcggtttg tttctggata
    38941 gcctcttcaa tagtggctgt aagggagttg gtttcagtct ggtcaggttg gtcatatcca
    39001 tttaaaaaat catgtatttt atttagaact tgctggaatt tatgtctcat attggcctcc
    39061 cttcttttat atcaatatta tataaaattt tcctaaaatc tacaagattt tacgaataaa
    39121 ctaatgaaac taaaaaagga gaagaaaatg gcagaattta catttgaaat cgaagagcac
    39181 ttgttgactc tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg tgtgagcttt
    39241 aatggtgccc ctgcaaagtt tgatattcgt gcttggagtc cagaccatac taaaatgggc
    39301 aaagggatta ctctctcaaa tgaagaattt caaacgatgg tggatgcctt taaaggcaac
    39361 taatactctt cgaaaatctc ttcaaaccgc gtcagctttg ccttgccgta tgtatggtt
//
LOCUS       DAVLBN010000014        38432 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLBN010000014 DAVLBN010000000
VERSION     DAVLBN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.014"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            153..380
                     /locus_tag="VXC24_000715"
     CDS             153..380
                     /locus_tag="VXC24_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492863.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            668..3565
                     /gene="nanA"
                     /locus_tag="VXC24_000716"
     CDS             668..3565
                     /gene="nanA"
                     /locus_tag="VXC24_000716"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0492864.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4580..5032
                     /locus_tag="VXC24_000717"
     CDS             4580..5032
                     /locus_tag="VXC24_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0492865.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5051..6388
                     /locus_tag="VXC24_000718"
     CDS             5051..6388
                     /locus_tag="VXC24_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0492866.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6467..7351
                     /locus_tag="VXC24_000719"
     CDS             6467..7351
                     /locus_tag="VXC24_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0492867.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7351..8184
                     /locus_tag="VXC24_000720"
     CDS             7351..8184
                     /locus_tag="VXC24_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0492868.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8202..10295
                     /gene="nanB"
                     /locus_tag="VXC24_000721"
     CDS             8202..10295
                     /gene="nanB"
                     /locus_tag="VXC24_000721"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0492869.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10307..11410
                     /locus_tag="VXC24_000722"
     CDS             10307..11410
                     /locus_tag="VXC24_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0492870.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11583..12281
                     /locus_tag="VXC24_000723"
     CDS             11583..12281
                     /locus_tag="VXC24_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0492871.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12300..13817
                     /locus_tag="VXC24_000724"
     CDS             12300..13817
                     /locus_tag="VXC24_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0492872.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            13942..15270
                     /locus_tag="VXC24_000725"
     CDS             13942..15270
                     /locus_tag="VXC24_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0492873.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15522..16388
                     /locus_tag="VXC24_000726"
     CDS             15522..16388
                     /locus_tag="VXC24_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0492874.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16404..17243
                     /locus_tag="VXC24_000727"
     CDS             16404..17243
                     /locus_tag="VXC24_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0492875.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17515..17967
                     /locus_tag="VXC24_000728"
     CDS             17515..17967
                     /locus_tag="VXC24_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0492876.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18100..18408
                     /locus_tag="VXC24_000729"
     CDS             18100..18408
                     /locus_tag="VXC24_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492877.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            18418..18717
                     /locus_tag="VXC24_000730"
     CDS             18418..18717
                     /locus_tag="VXC24_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492878.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            18699..19343
                     /locus_tag="VXC24_000731"
     CDS             18699..19343
                     /locus_tag="VXC24_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0492879.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19512..20429
                     /locus_tag="VXC24_000732"
     CDS             19512..20429
                     /locus_tag="VXC24_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0492880.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20447..21331
                     /locus_tag="VXC24_000733"
     CDS             20447..21331
                     /locus_tag="VXC24_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0492881.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21347..22198)
                     /locus_tag="VXC24_000734"
     CDS             complement(21347..22198)
                     /locus_tag="VXC24_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0492882.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22398..24455
                     /gene="pbp2b"
                     /locus_tag="VXC24_000735"
     CDS             22398..24455
                     /gene="pbp2b"
                     /locus_tag="VXC24_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0492883.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24466..25062
                     /gene="recR"
                     /locus_tag="VXC24_000736"
     CDS             24466..25062
                     /gene="recR"
                     /locus_tag="VXC24_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0492884.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25238..26281
                     /locus_tag="VXC24_000737"
     CDS             25238..26281
                     /locus_tag="VXC24_000737"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0492885.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26365..27738
                     /locus_tag="VXC24_000738"
     CDS             26365..27738
                     /locus_tag="VXC24_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0492886.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            27725..28336
                     /locus_tag="VXC24_000739"
     CDS             27725..28336
                     /locus_tag="VXC24_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0492887.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28427..29131
                     /locus_tag="VXC24_000740"
     CDS             28427..29131
                     /locus_tag="VXC24_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0492888.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29350..30723
                     /gene="ftsA"
                     /locus_tag="VXC24_000741"
     CDS             29350..30723
                     /gene="ftsA"
                     /locus_tag="VXC24_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0492889.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30740..31999
                     /gene="ftsZ"
                     /locus_tag="VXC24_000742"
     CDS             30740..31999
                     /gene="ftsZ"
                     /locus_tag="VXC24_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0492890.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32004..32675
                     /locus_tag="VXC24_000743"
     CDS             32004..32675
                     /locus_tag="VXC24_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0492891.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32685..33224
                     /locus_tag="VXC24_000744"
     CDS             32685..33224
                     /locus_tag="VXC24_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0492892.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33224..33487
                     /locus_tag="VXC24_000745"
     CDS             33224..33487
                     /locus_tag="VXC24_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0492893.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33484..34269
                     /locus_tag="VXC24_000746"
     CDS             33484..34269
                     /locus_tag="VXC24_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0492894.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34278..35066
                     /gene="divIVA"
                     /locus_tag="VXC24_000747"
     CDS             34278..35066
                     /gene="divIVA"
                     /locus_tag="VXC24_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0492895.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35414..38206
                     /locus_tag="VXC24_000748"
     CDS             35414..38206
                     /locus_tag="VXC24_000748"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0492896.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        11985 a         6709 c         8363 g        11375 t
ORIGIN      
        1 aaaaatgagg tataataaat ttactaacac ttataaaaag tgatagaatc tatctttatg
       61 tatatttaaa gatagattgc tgtaaaaata gtagtagcta tgcgaaataa cagatagaga
      121 gaagggattg aagcttagaa aaggggaata atatgatatt taaggcattc aagacaaaaa
      181 agcagagaaa aagacaagtt gaactacttt tgacagtttt tttcgacagt tttctgattg
      241 atttatttct tcacttattt gggattgtcc cctttaagct ggataagatt ctgattgtga
      301 gcttgattat atttcccatt atttctacaa gtatttatgc ttatgaaaag ctatttgaaa
      361 aagtgttcga taaggattga gcaggaagta tggtataaat agcataagct gatgtccatc
      421 atttgcttat aaagagatat tttagtttaa ttgcagcggt gtcctggtag ataaactaga
      481 ttggcaggag tctgattgga gaaaggagag gggaaaattg gcaccaattt gagatagttt
      541 gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa gaaagttaat aaaagacaaa
      601 ctaagtgcat tttctggagt aaatgtctta tttcagaaat cgggatatag atatagagag
      661 gatcagtatg aatcggagtg ttcaagaacg taagtgtcgt tatagcatta ggaaactatc
      721 ggtaggagcg gtttctatga ttgtaggagc agtggtattt ggaacgtctc ctgttttagc
      781 tcaagaaggg gcaagtgagc aacctctggc aaatgaaact caactttcgg gggagagctc
      841 aaccctaact gatacagaaa agagccagcc ttcttcagag actgaacttt ctggcaataa
      901 gcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt ccaagagatt actatgcacg
      961 agatttggaa aatgtcgaaa cagtgataga aaaagaagat gttgaaacca atgcttcaaa
     1021 tggtcagaga gttgatttat caagtgaact agataaacta aagaaacttg aaaacgcaac
     1081 agttcacatg gagtttaagc cagatgccaa ggccccagca ttctataatc tcttttctgt
     1141 gtcaagtgct actaaaaaag atgagtactt cactatggca gtttacaata atactgctac
     1201 tctagagggg cgtggttcgg atgggaaaca gttttacaat aattacaacg atgcaccctt
     1261 aaaagttaaa ccaggtcagt ggaattctgt gactttcaca gttgaaaaac cgacagcaga
     1321 attgccaaat ggtcgagttc gcctgtatgt taatggtgtt ttatctcgaa caagtctgaa
     1381 atctggcaat ttcattaaag atatgccaga tgtaacgcat gtgcaaatcg gagcaaccaa
     1441 gcgtgccaac aatacggttt gggggtcaaa tctacagatt cggaatctca ctgtgtataa
     1501 tcgtgcttta acaccagaag aggtacaaaa acgtagtcaa ctttttaaac gctcagattt
     1561 agaaaaaaaa ctacctgaag gagcggcttt aacagagaaa acggacatat tcgaaagcgg
     1621 gcgtaacggt aaaccaaata aagatggaat caagagttat cgtattccag cacttctcaa
     1681 gacagataaa ggaactttga tcgcaggtgc agatgaacgc cgtctccatt cgagtgactg
     1741 gggtgatatc ggtatggtca tcagacgtag tgaagataat ggtaaaactt ggggtgaccg
     1801 agtaaccatt accaacttac gtgacaatcc aaaagcttct gacccatcga tcggttcacc
     1861 agtgaatatc gatatggtgt tggttcaaga tcctgaaacc aaacgaatct tttctatcta
     1921 tgacatgttc ccagaaggga agggaatctt tggaatgtct tcacaaaaag aagaagccta
     1981 caaagaaatc gatggaaaaa cctatcaaat cctctatcgt gagggagaaa aggaagctta
     2041 taccattcga gaaaatggta ctgtctatac accagatggt aaggcgacag actatcgcgt
     2101 tgttgtagat cctgttaaac cagcctatag cgacaagggt gatctataca agggtgacca
     2161 attactagga aatatctact tcacaacaaa caaaacttct ccatttagaa ttgccaagga
     2221 tagctatcta tggatgtcct acagtgatga cgacgggaag acatggtcag cgcctcaaga
     2281 tattactccg atggtcaaag ccgattggat gaaattcttg ggtgtaggtc ctggaacagg
     2341 aattgtactt cggaatgggc ctcacaaggg acggattttg ataccggttt atacgactaa
     2401 taatgtatct cacttaaatg gctcgcaatc ttctcgtgtc atctattcag atgatcatgg
     2461 aaaaacttgg catgctggag aagcggtcaa cgataaccgt caggtagacg gtcaaaagat
     2521 ccactcttct acgatgaaca ataaacgtgc gcaaaataca gaatcaacgg tggtacaact
     2581 aaacaatgga gatgttaaac tctttatgcg tggtttgact ggagatcttc aggttgctac
     2641 aagtaaagac ggaggagtga cttgggagaa ggatatcaaa cgttatccac aggttaaaga
     2701 tgtctatgtt caaatgtctg ctatccatac gatgcacgaa ggaaaagaat acatcatcct
     2761 cagtaatgca ggtggaccga aacgtgaaaa tgggatggtc cacttggcac gtgtcgaaga
     2821 aaatggtgag ttgacttggc tcaaacacaa tccaattcaa aaaggagagt ttgcctataa
     2881 ttcgctccaa gaattaggaa atggggagta tggcatcttg tatgaacata ctgaaaaagg
     2941 acaaaatgcc tataccctat catttagaaa atttaattgg gaatttttga gcaaaaatct
     3001 gatttctcct accgaagcga aagtgaagcg aactagagag atgggcaaag gagagatggg
     3061 caaaggagtt attggcttgg agttcgactc agaagtattg gtcaacaagg ctccaaccct
     3121 tcaattggca aatggtaaaa cagcgacttt cctaacccag tatgatagca agaccttgtt
     3181 gtttgcagta gataaggaag atatcggaca ggaaattatt ggtatagcta aaggaagcat
     3241 cgaaagtatg cataatcttc ctgtaaatct agcaggtgcc agagttcctg gcggagtaaa
     3301 tggtagcaaa gcagcggtgc atgaagttcc agaatttaca gggggagtta atggtacaga
     3361 gccagctgtt catgaaatcg cagagtataa gggatctgat tcgcttgtaa ctcttactac
     3421 aaaagaagat tatacttaca aagctcctct tgctcagcag gcacttcctg aaacaggaaa
     3481 caaggagagt gacctcctag cttcactagg actaacagct ttcttccttg gtctgtttac
     3541 gctagggaaa aagagagaac aataagagaa gaattctaaa catttgattt tgtaaaaata
     3601 gaaggagata gcaggttttt aagcctgcta tctttttttg atgacattca ggctgatacg
     3661 aaatcataag aggtctgaaa ctactttcag agtagtctgt tctataaaat atagtagatt
     3721 gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa aaattttagc
     3781 agtcaaggtg tactgttata aattcaatat attatacgac tattaacctt atcttctcct
     3841 aaaattgact ttcttgtttt cttatcttgt ctactcgaaa caagtattgt aagaatttga
     3901 ttatttttga aagtactttt aatatacttg atatagttaa aaaagatttg aaactaaatt
     3961 ccaaattaga aaaagacttg aaatactaaa aaaaaaaagt atactctaat tgaaaacggt
     4021 aacaaaacta atttagagaa tgaaatatag agtatttctc tcttaaaagt ttttggtgaa
     4081 acgagatgta gaaaggagat ttagccaaag agtctattag tgctagaata atagattaga
     4141 attattttag aaaaacgaag tgagcagctt ataaattcaa gtccccaaat agattcatac
     4201 tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg aatatcaatt tcatctataa
     4261 ggaaggtagc taattgaact aacttattta ttctgtttgt cgctagaaaa atcagacctc
     4321 cttgtgaaga ttgaggagat actgaatgaa aatcaaagaa gaaactagca agctagtagc
     4381 agattgccca aaacaccgct ttgaggttgt agataagact gacgtatata atccaaggtg
     4441 aagcgactgt ggtttgaaga gattttcaaa gagtataggc tagagagtag tgtttttatg
     4501 tccttctagt agaaaatgct agacagaaga atggggaact tggataggaa aaatagattg
     4561 agaaaggagg ttagaagaga tgattattac aaaaattagc cgtttaggaa cttatgtggg
     4621 agtaaatcca cattttgcaa cattaataga ttttttagaa aaaacaggac tagaaaattt
     4681 aacagaaggt tcgattgcta tcgatggtaa tcgattgttt gggaattgct ttacttatct
     4741 agcagatggt caagcagggg ctttctttga aacacaccaa aaatatttgg atattcattt
     4801 agttttggaa aacgaagaag ccatggctgt tacatcgccg gaaaatgtaa gcgttaccca
     4861 agaatatgat gaagagaaag atattgaatt atacacaggg aaagtggaac agttggttca
     4921 tttgagagct ggtgaatgcc tcatcacttt tccagaagat ttacatcaac ccaaggttcg
     4981 tataaatgat gaacctgtga aaaaagttgt ctttaaagtt gcgatttctt aatgtagaaa
     5041 gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta gctggaattg cgctagcggc
     5101 tgttgccttg gtagcttgtt caggaaaaaa agaagctaca actagtactg aaccaccaac
     5161 agaattatct ggtgagatta caatgtggca ctcctttact caaggacccc gtttagaaag
     5221 tattcaaaaa tcagcagatg ctttcatgca aaagcatcca aaaacgaaaa tcaagattga
     5281 aacattttct tggaatgact tctatactaa atggactaca ggtttagcaa atggaaatgt
     5341 gccagatatc agtacagctc ttcctaacca agtaatggaa atggtcaact cagatgcttt
     5401 ggttccgcta aatgattcta tcaagcgtat tggacaagat aaatttaacg aaactgcctt
     5461 aaatgaagca aaaatcggag atgattacta ctctgttcct ctttattcac atgcacaagt
     5521 catgtgggtt agaacagatt tgttaaaaga acataatatt gaggttccta aaacttggga
     5581 tcaactctat gaagcttcta aaaaattgaa agaagctgga gtttatggct tgtctgttcc
     5641 gtttggaaca aatgacttaa tggcaacacg tttcttgaac ttctacgtac gtagtggtgg
     5701 aggaagcctc ttaacaaaag atcttaaagc agacttgaca agccaacttg ctcaagatgg
     5761 tattaaatac tgggttaaat tgtataaaga aatctcacct caagattctt tgaactttaa
     5821 tgtccttcaa caagctacct tgttctatca aggaaaaaca gcatttgact ttaactctgg
     5881 cttccatatc ggaggaatta atgccaacag tcctcaattg attgattcga ttgatgctta
     5941 tcctattcca aaaatcaaag agtctgataa agaccaagga attgaaacct caaacattcc
     6001 aatggttgtt tggaaaaatt caaaacatcc agaagttgct aaagcattct tagaagcact
     6061 ttataatgaa gaagactacg ttaaattcct tgattcaact ccagtaggta tgttgccaac
     6121 tattaagggg attagcgatt ctgcagccta taaagaaaat gaaactcgta agaaatttaa
     6181 acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt actgctattg gttatgaaaa
     6241 tggaccaagt gtacaagctg gtatgttaac taaccaacac attattgaac aaatgttcca
     6301 agatatcatt acaaatggaa cagatcctat gaaagcagca aaagaagcag aaaaacaatt
     6361 aaacgattta tttgaggctg ttcagtagat gtaaaagact agaaaatagg tgggctagtg
     6421 agctgaaaag ctctagccca atcttgtaaa agaagggaga aggagaatgg ttaaagaacg
     6481 taatttaact cgctggatat ttgttttgcc agctatgatt atcgtaggat tactctttgt
     6541 ttatccgttt ttctcgagta ttttttatag ctttaccaat aagcatttga ttatgcctaa
     6601 ttataaattt gttggtttgg ctaactataa agctgtgctg tcagatccca acttctttaa
     6661 tgcgttcttt aattcaatta agtggaccgt tttctcatta gttggtcaag ttttagtagg
     6721 gtttgtattg gctttagctc ttcacagagt acgccacttc aagaaattat ataggacctt
     6781 attgattgtt ccttgggcat ttcctaccat cgttattgcc ttctcttggc agtggattct
     6841 aaacggggtt tatggctact tacctaatct aatcgtaaaa ttaggtttaa tggaacatac
     6901 acctgcattt ttgacagata gtacatgggc attcctatgt ttggtgttta tcaacatttg
     6961 gtttggagca ccaatgatta tggttaatgt gctttcagct ttgcaaacag taccagaaga
     7021 acaatttgag gctgctaaga tagatggtgc ttcaagttgg caggtgttca agtttatcgt
     7081 ctttccacat attaaagtgg ttgtaggact tctagttgtt ttgagaactg tatggatctt
     7141 taataacttt gacattatct acctcattac tggtggtgga ccagccaatg ctacaacgac
     7201 acttccaatt tttgcttaca acctgggttg gggaactaaa ttgttgggtc gtgcttcagc
     7261 agttacagta ttgctcttta tcttcttggt ggcgatttgc tttatctact ttgctatcat
     7321 cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga aatccagtat ttatttagat
     7381 attctctcac atgtactttt agttggtgcg accatcgttg caattttccc attggtatgg
     7441 attatcatat cttctgtcaa agggaaaggg gaattaactc agtatccaac acgattttgg
     7501 cctgaacagt ttacattaga ttatttcact catgttatca acgatttgca cttcattgat
     7561 aacattcgaa acagtttaat cattgccttg gctacaaccc tcattgcgat tattatttct
     7621 gctatggcag cctatggtat tgttcgattc tttcctaaat tgggagcaat catgtcgaga
     7681 ctactcgtca ttacctacat tttcccacca attttgttag caattcccta ttcaattgcc
     7741 attgctaaag ttgggttaac aaatagttta tttggcttga tgatggttta tctatctttt
     7801 agtgttccat atgcagtttg gctcttagtt ggatttttcc aaacagttcc aattggaatt
     7861 gaagaagcgg ctagaattga tggtgcaaat aaatttgtta cgttttataa ggttgtgcta
     7921 ccgattgtag caccaggtat tgtagcaaca gctatttata catttatcaa tgcttggaat
     7981 gaattcctgt atgccttgat tttaattaac aatacaggaa agatgacagt agcagtagcc
     8041 cttcgttcac ttaatggttc agaaatacta gactggggag atatgatggc agcgtctgtt
     8101 attgtagttc ttccatcaat tattttcttc tctatcatcc aaaataagat tgcaagtgga
     8161 ttatcagaag gatctgtgaa gtagacgaaa gaaggaaaaa aatgaataaa agaggtcttt
     8221 attcaaaact aggaatttct gttgtaggca ttagtctttt aatgggagtc cccactttga
     8281 ttcatgcgaa tgaattaaac tatggtcaac tgtccatatc tcctattttt caaggaggtt
     8341 catatcaact gaacaataag agtatagata tcagctcttt gttattagat aaattgtctg
     8401 gagagagtca gacagtagta atgaaattta aagcagataa accaaactct cttcaagctt
     8461 tgtttggcct atctaatagt aaagcaggct ttaaaaataa ttacttttca attttcatga
     8521 gagattctgg tgagataggt gtagaaataa gagacgccca aaagggaata aattatttat
     8581 tttctagacc agcttcatta tggggaaagc ataaaggaca ggcagttgaa aatacactag
     8641 tatttgtatc tgattctaaa gataaaacat acacaatgta tgttaatgga atagaagtgt
     8701 tctctgaaac agttgataca tttttgccaa tttcaaatat aaatggtata gataaggcaa
     8761 cactaggagc tgttaatcgt gaaggtaagg aacattacct cgcaaaagga agtattggtg
     8821 aaatcagtct atttaacaaa gcaattagtg atcaggaagt ttcaaatatt cccttgtcaa
     8881 atccatttca gttaattttc caatcaggag attctactca agctaactat tttagaatac
     8941 cgacactata tacattaagt agtggaagag ttctatcaag tattgatgca cgttatggtg
     9001 ggactcatga ttctaaaagt aagattaata ttgccacttc ttatagtgat gataatggga
     9061 aaacgtggag tgagccaatt tttgctatga agtttaatga ctatgaggag cagttagttt
     9121 actggccacg agataataaa ttaaagaata gtcaaattag tggaagtgct tcattcatag
     9181 attcatccat tgttgaagat aaaaaatctg ggaaaacgat attactagct gatgttatgc
     9241 ctgcgggtat tggaaataat aatgcaaata aagccgactc aggttttaaa gaaataaatg
     9301 gtcattatta tttaaaacta aagaagaatg gagataacga tttccgttat acagttagag
     9361 aaaatggtgt cgtttatgat gaaacaacta ataaacctac aaattatact ataaatgata
     9421 agtatgaagt tttggaggga ggaaagtctt taacagtcga acaatattcg gttgattttg
     9481 atagtggctc tttaagagaa aggcataatg gaaaacaggt tcctatgaat gttttctaca
     9541 aagattcgtt atttaaagtg actcctacta attatatagc aatgacaact agtcagaata
     9601 gaggagagag ttgggaacaa tttaagttgt tgcctccgtt cttaggagaa aaacataatg
     9661 gaacttactt gtgtcctgga caaggtttag cattaaaatc aagtaacaga ttgatttttg
     9721 caacatatac tagtggagaa ctaacctatc tcatttcgga tgatagtggt caaacatgga
     9781 agaaatcctc agcttcaatt ccgtttaaaa atgcaacagc agaagcacaa atggttgaac
     9841 tgagagatgg tgtgattaga acattcttta gaaccactac aggtaagata gcttatatga
     9901 ctagtagaga ttctggagaa acatggtcga aagtttcgta tattgatgga attcaacaaa
     9961 cttcatatgg cacacaagta tctgcaatta aatactctca attaattgat ggaaaagaag
    10021 cagtcatttt gagtacacca aattctagaa gtggccgtaa gggaggccaa ttagttgtcg
    10081 gtttggtcaa taaagaagat gatagtattg attggagata ccactatgat attgatttgc
    10141 cttcgtatgg ttatgcctat tctgcgatta cagaattgcc aaatcatcac ataggtgtac
    10201 tgtttgaaaa atatgattcg tggtcgagaa atgaattgca tttaagcaat gtagttcagt
    10261 atatagattt ggaaattaat gatttaacaa aataaaggag aaaaacatgg ttaaatacgg
    10321 tgttgttgga gcagggtatt ttggagctga attggctcgc tacatgcaaa agaatgatgg
    10381 agcagagatt actcttctct atgatccaga taatgcagag gcgattgcag aagaattggg
    10441 agcaaaagta gcaagttcct tagatgagtt ggtttctagc gatgaagtag attgtgttat
    10501 cgtcgcaact ccaaataatc ttcataagga accggttatt aaggctgcac agcatggtaa
    10561 aaatgttttc tgtgaaaaac caattgcgct ttcttatcaa gattgtcgcg agatggtaga
    10621 tgcgtgtaaa gaaaacaatg taacctttat ggcaggacat attatgaatt tctttaatgg
    10681 tgttcatcat gcaaaagaac tcattaatca aggagttatc ggagacgttc tatattgtca
    10741 tacagctcgt aatggttggg aagaacaaca actgtcagta tcatggaaaa aaattcgtga
    10801 aaaatcaggt ggtcacttgt atcaccacat ccatgaattg gattgcgttc aattccttat
    10861 ggggggcatg cctgaaactg taaccatgac aggtggaaat gtggcccatg aaggtgaaca
    10921 tttcggtgat gaagatgata tgatttttgt caatatggaa ttttctaata agcgttttgc
    10981 cttgttagaa tggggttcag cttatcgttg gggtgaacat tatgtcttaa tccaaggaag
    11041 caaaggtgcc atccgcttag acttattcaa ctgtaaagga actcttaagc tagatgggca
    11101 agaaagctat ttcttgattc acgaatcgca agaagaagat gatgatcgga ctcgtatcta
    11161 tcatagtaca gagatggatg gagcaattgc ttatggtaaa ccaggtaaac gtactccatt
    11221 atggctatca tctgtcattg ataaagaaat gcgctatctg catgagatta tggaaggagc
    11281 tccagtatca gaagaatttg caaaactttt gacaggtgaa gctgccctag aagcaattgc
    11341 tactgcagat gcttgtaccc agtctatgtt tgaagatcgc aaagtaaaat tgtcagaaat
    11401 tgtaaaataa attttggtat tctcctatta taggtcgact tgctcctctg aaagtacttt
    11461 tagaggagct gtttgacttg gctagttttt gaaactgaaa tctattatac tacaaactat
    11521 tgaaagcgtt ttaattttaa ggtataataa tctcatagaa ataaagaaaa ggaggaaaga
    11581 ggatgccaca gattagcaaa gaagccttga ttgagcaaat caaagatgga atcatcgttt
    11641 cttgtcaggc tcttcctcat gaaccgcttt atacagaagc gggaggggtg attcccttgc
    11701 tggtcaaagc ggctgagcaa ggtggagcag tcggtatccg agcaaacagt gttcgcgata
    11761 tcaaggaaat taaggaagtc actaaacttc caatcattgg gattatcaaa cgtgattatc
    11821 cacctcagga acccttcatc acggctacta tgaaagaagt tgatgaattg gcagaactgg
    11881 acatcgaggt gattgctctg gattgtacca agcgtgaacg ctacgatggt ttggaaattc
    11941 aagagttcat tcgtcaggtt aaggagaaat atcctaatca gcttttgatg gctgatacta
    12001 gtatcttcga agaagggcta gcagctgtag aagcaggaat tgactttgtc ggaacaacct
    12061 tatcaggcta cacatcctac agtccaaaag tagacggtcc agattttgaa ttgattaaga
    12121 aactctgtga tgccggtgta gatgtcattg cagaaggaaa aattcataca ccagaacaag
    12181 ccaaacaaat ccttgaatat ggagtgcgag gcatcgttgt tggtggcgcc attactagac
    12241 caaaagagat tacagaacgc ttcgttgcta gtcttaaata agatgtgagg gggagtttta
    12301 tgtttaaagt tttacaaaaa gttggaaaag cttttatgtt acctatagct atacttcctg
    12361 cagcaggtct acttttgggg attggtggtg cactttcaaa cccaaccacg atagcaactt
    12421 atccaatact agacaatagt atttttcaat caatattcca agtaatgagc tctgcaggag
    12481 aggttgtatt cagtaatttg tcactacttc tctgtgtggg attatgtatt ggcttagcga
    12541 aacgagataa aggaaccgct gcgttagcag gagtaactgg ttacttagtt atgactgcaa
    12601 cgatcaaagc tttggtaaaa ctttttatgg cagaaggatc tgcaattgat actggagtta
    12661 ttggagcatt agttgtcgga atagttgccg tatatttgca caaccgatat aacaatattc
    12721 aattaccttc cgctttagga ttctttggag gttcacgctt cgttcctatt gttacatcgt
    12781 tctcttctat cttgattggc tttgtcttct ttgttatttg gccacctttc caacaacttc
    12841 ttgtttctac aggtggatat atttctcagg cgggtccaat tggaactttt ctatatggat
    12901 ttttaatgag actttctgga gcagtaggct tacatcatat aatttaccct atgttttggt
    12961 atactgaact tggtggtgtt gaaactgttg caggacaaac agtggttgga gctcaaaaaa
    13021 tattttttgc tcaattagcc gatccggccc attctggatt atttacagaa ggaacaaggt
    13081 tttttgcagg tcgtttctca acaatgatgt tcggtttacc ggctgcctgt ttagcgatgt
    13141 accatagtgt tcctaaaaat cgtcgtaaaa aatacgcggg tttgtttttt ggagttgctt
    13201 taacatcttt tattaccggt attacagaac caattgaatt tatgtttcta ttcgtcagtc
    13261 cggttctata tgttgttcac gcattccttg atggtgttag cttctttatt gcagacgtct
    13321 taaatatttc aataggaaac acattttcag gaggtgtaat cgatttcact ttatttggaa
    13381 ttttgcaggg gaacgctaag acgaattggg ttcttcagat tccaattgga cttatttgga
    13441 gtgttttgta ttatattatt tttagatggt tcattactca attcaacgtt ctaacgccag
    13501 gacgaggaga agaagtagat tctaaagaaa tttctgaatc cgcagattca acttcaaata
    13561 ctgcagatta tttaaaacag gatagcctac aaattatcag agccttgggt ggatcaaata
    13621 atatagaaga tgtagatgct tgtgtgacac gtttacgtgt agctgtaaaa gaagttaatc
    13681 aagttgataa agcactttta aaacaaattg gtgcagttga tgtcttagaa gtgaagggtg
    13741 gcattcaagc aatctatgga gcaaaagcaa tcttatataa aaatagtatt aatgaaattt
    13801 taggtgtaga tgattaagta cttactgact taataaaaaa cagaggagag tgatggatga
    13861 gtaggatgaa atgaaatcgc atacaagaaa taaagaactc attatccaag ttggatacgc
    13921 ttattacata ggagaataca aatgaaattt agaaaattag cttgtacagt acttgcgggt
    13981 gctgcggttc ttggtcttgc tgcttgtggc aattctggcg gaagtaaaga tgctgccaaa
    14041 tcaggtggtg acggtgccaa aacagaaatc acttggtggg cattcccagt atttacccaa
    14101 gaaaaaactg gtgacggtgt tggaacttat gaaaaatcaa tcatcgaagc gtttgaaaaa
    14161 gcaaacccag atataaaagt gaaattggaa accatcgact tcaagtcagg tcctgaaaaa
    14221 atcacaacag ccatcgaagc aggaacagct ccagacgtac tctttgatgc accaggacgt
    14281 atcatccaat acggtaaaaa cggtaaattg gctgagttga atgacctctt cacagatgaa
    14341 tttgttaaag atgtcaacaa tgaaaacatc gtacaagcaa gtaaagctgg agacaaggct
    14401 tatatgtatc cgattagttc tgccccattc tacatggcaa tgaacaagaa aatgttagaa
    14461 gatgctggag tagcaaacct tgtaaaagaa ggttggacaa ctgatgattt tgaaaaagta
    14521 ttgaaagcac ttaaagacaa gggttacaca ccaggttcat tgttcagttc tggtcaaggg
    14581 ggagaccaag gaacacgtgc ctttatctct aacctttata gcggttctgt aacagatgaa
    14641 aaagttagca aatatacaac tgatgatcct aaattcgtca aaggtcttga aaaagcaact
    14701 agctggatta aagacaattt gatcaataat ggttcacaat ttgacggtgg ggcagatatc
    14761 caaaactttg ccaatggtca aacatcttac acaatccttt gggcaccagc tcaaaatggt
    14821 atccaagcta aacttttaga agcaagtaag gtagaagtgg tagaagtacc attcccatca
    14881 gacgaaggta agccagctct tgaatacctt gtaaacgggt ttgcagtatt caacaataaa
    14941 gacgacaaga aagtcgctgc atctaagaaa ttcatccagt ttatcgcaga tgacaaggag
    15001 tggggaccta aagacgtagt tcgtacaggt gctttcccag tccgtacttc atttggaaaa
    15061 ctttatgaag acaaacgcat ggaaacaatc agcggctgga ctcaatacta ctcaccatac
    15121 tacaacacta ttgatggatt tgctgaaatg agaacacttt ggttcccaat gttgcaatct
    15181 gtatcaaatg gtgacgaaaa accagcagat gctttgaaag ccttcactga aaaagcgaac
    15241 gaaacaatca aaaaagctat gaaacaatag tccttagtta ttctataaaa agtagttttt
    15301 taaagaacct aagagtgtat accccctttt ccctctacac agatagtgta agaaaagggg
    15361 gcttttgttt aaaatgtaag aaactgtcac gaaattaaaa tgaagttctt acataagcga
    15421 atcataaaaa atttcatttt gattttaaaa cagttcaaga aagtcaaaaa attattctat
    15481 ttgaaagaga ggtgccgact gtgaaagtca ataaaatccg tatgcgggaa acagtgattt
    15541 cctacgcttt cctagcacca gtattattct tctttgtcat ctttgtgttg gctccgatgg
    15601 tgatgggctt cattacaagt ttctttaact actcaatgac taaatttgag tttgtaggct
    15661 tggataacta tatccgtatg tttaaagatc ctgtctttac aaaatctctg attaacacag
    15721 ttattttggt tattggatct gtaccagttg ttgttctatt ctcactcttt gtagcatctc
    15781 agacctatca tcaaaatgtc attgccagat ccttctaccg tttcgtcttc ttccttcctg
    15841 ttgtaacggg tagtgttgcc gtgacagttg tttggaaatg gatttatgac ccactatcag
    15901 ggattctaaa ctttgtcctt aagtccagcc acatcatcag ccaaaacatt tcttggttgg
    15961 gagataaaaa ctgggcattg atggcgatta tgattattct cttgaccact tcagttggtc
    16021 agcccatcat cctttatatc gctgccatgg ggaatattga caattcactg gttgaagcgg
    16081 cgcgtgttga tggtgcaact gagtttcaag ttttttggaa gattaaatgg ccaagccttc
    16141 ttccaacaac tctttatatt gcaatcatca caacaattaa ctcattccag tgttttgcct
    16201 tgattcagct tttgacatct ggtggtccaa actactcaac aagtaccttg atgtactacc
    16261 tttacgaaaa agccttccaa ttgacagaat acggctatgc caacacaatt ggtgtcttct
    16321 tggcagtcat gattgctatc gtaagctttg ttcaatttaa agtacttgga aacgacgtag
    16381 aatactaaag aaaggagaca gctatgcaat ctacagaaaa aaaaccatta acagccttta
    16441 ctgttatttc aacaatcatt ttgctcttgt tgactgtgct gttcatcttt ccattctact
    16501 ggattttgac aggggcattc aaatcacaac ctgatacaat tgttattcct cctcagtggt
    16561 tccctaaaat gccaaccatg gaaaacttcc aacaactcat ggtgcagaac cctgccttgc
    16621 aatggatgtg gaactcagta tttatctcat tggtaaccat gttcttagtt tgtgcaacct
    16681 catctctagc aggttatgta ttggctaaaa aacgtttcta tggtcaacgc attctatttg
    16741 ctatctttat cgctgctatg gcgcttccaa aacaagttgt ccttgtacca ttggtacgta
    16801 tcgtcaactt catgggaatc cacgatactc tctgggcagt tatcttgcct ttgattggat
    16861 ggccattcgg tgtcttcctc atgaaacaat ttagtgaaaa tattcctaca gagttgcttg
    16921 aatcagctaa aatcgacggt tgtggtgaga ttcgtacctt ctggagtgta gccttcccga
    16981 ttgtgaaacc agggtttgca gcccttgcaa tctttacctt catcaatact tggaatgact
    17041 acttcatgca attggtaatg ttgacttcac gtaacaattt gaccatctca cttggggttg
    17101 cgaccatgca ggctgaaatg gcaaccaact atggtttgat tatggcagga gctgcccttg
    17161 ctgctgttcc aatcgtcaca gtcttcctag tcttccaaaa atccttcaca cagggtatta
    17221 ctatgggagc ggtcaaagga taatactctg agaaaatctc ttcaaactac gtcagcgtca
    17281 ccttgccata cttaagtatt gcctgcggtt agcttcctag tttgttcttc aattttcatt
    17341 gagtatagga aaatcaatct atcaagatac agaagtatat tttatagatt tagagaatat
    17401 agaggttata agtgtctaca aaatggaggg tatgcagtta ctttatgaag ttttgtcaga
    17461 cacttataaa cttaagaatg gttttagtta actatcagaa acgaaggaaa gagtatgatt
    17521 tttgacgatt tgaaaaacat caccttttac aaagggattc atcctaattt agacaaggct
    17581 atcgactatc tctaccaaca tcgtaaggat tctttcgaat taggaaagta tgatattgat
    17641 ggagataaag tctttctagt tgttcaggaa aatgtcctca atcaagctga aaatgatcaa
    17701 tttgagtatc ataagaacta tgcagatttg catttgctgg tagaaggaca tgaatattcg
    17761 agctacggtt cacgtatcaa agacgaggca gtagcattcg acgaagcgag tgacattggc
    17821 tttgttcatt gtcatgaaca ctacccactc ttgttgggtt atcacaattt tgcgattttc
    17881 ttcccaggtg agccacatca gccaaatggt tatgcaggca tggaagaaaa ggttcggaaa
    17941 tatctcttta aaattttgat tgattaaaaa taggatgaat tgtttttttg taaagctttg
    18001 acaatactct accatgaaat tgatctttgt gaggtaggga aatgagaata aaatatttaa
    18061 aaattggtat cttctaagta tgctgcaaga gctagtttct tggatggaca gggaattaca
    18121 gttgatgaga tggcttggat aattaggggc attgtgaatg gattgattgg tagatacata
    18181 aaattaggta cttatgcagc caagtatggt attagtatgg cgcgttcgat cttaagtagg
    18241 gcagctgcaa ctgcagcagc aagagtagga ttatcgacca agatttctgg atggatttta
    18301 cgagtagctg tgaatgtagc tgatgtatat ggtaattttg ccaacaatat tgctgcagct
    18361 tgggatgcac atgataaaat tcctaacaat ggtcgtataa acttttaaaa tgcgagaatg
    18421 aaagcacttt gtattttttt attgaatatg ttagcttgga cagtgcttgc aatgataatt
    18481 cgtggagggc tagatggatt tgatgagcat acttggagta ctattttaat tgcttcgctg
    18541 ttcggggtat atgattataa gcccatagat aaaaatagaa aaaagtccaa aagaaaaaag
    18601 aaaaaagaaa aaatagattt gttcatggta gggacttatg aaagctttac tgacaaaaaa
    18661 gaaaacagtt tacaaagaaa aatgatggag gagcaaacat ggcacaaaaa ggagtaagcc
    18721 ttatcaaggc agcatttgat acagacaact ttctcatgcg ttttagtgag aaagtcttgg
    18781 acatcgtgac agccaatctt ctttttgtcg tctcttgttt gcccatcgtg acgattggag
    18841 tggctaaaat cagcctctac gagaccatgt tcgaagttaa gaagagcaga cgggtgcctg
    18901 tttttaaaat ctatctaaga tctttcaagc aaaatctgaa actaggtctt cagctgggtt
    18961 taatggagtt aggaattgtg tttcttaccc tttcagatct ctatcttttc tggggtcaaa
    19021 cagctctgcc cttccaattg ctgaaagcca tttgtttagg tattctgatt tttcttacta
    19081 tcgtgatgct ggctagttac cctatcgcgg cacgttatga cctatcttgg aaagaaattc
    19141 ttcaaaaagg attgatgttg gctagtttta actttccttg gttcttcctc atgttagcca
    19201 ttcttgtcct cattgtgatg gttctttatc tgtccgcctt cagtctactc ttaggtggct
    19261 cagtcttctt actttttggg tttggactat tggtctttat ccagactgga ttgatggaga
    19321 aaattttcgc aaaataccaa taggagcctt atttctgaaa ctactttcaa acgctccaaa
    19381 cgctattcta taagcgagaa actaaaatct aagtgtctat aagatattga aagccttttc
    19441 ggtaaagtgt atactaaaga agtaaagaaa aatctgcttt agcagaaaat aaaaataata
    19501 ggagaaaatc tatgtcagat ttgaaaaaat acgaaggtgt cattccagcc ttctacgcat
    19561 gttatgatga acaaggagaa gtaagcccag aacgtacgcg tgccttggtt caatacttca
    19621 ttgataaagg tgttcaaggt ctttatgtca atggttcttc tggtgaatgt atctaccaaa
    19681 gtgttgaaga ccgcaagtta atcttggaag aagtcatggc ggtagccaaa ggtaaattga
    19741 ccatcattgc tcatgttgcc tgcaacaata ctaaagatag tatggaactt gctcgccatg
    19801 ctgaaagctt gggagtagat gctattgcaa cgattccacc aatttatttc cgcttgccag
    19861 aatactcagt tgccaaatac tggaacgata tcagttctgc agctccaaac acagactacg
    19921 tgatttacaa cattcctcaa ttggcagggg ttgctttgac tccaagcctt tacacagaaa
    19981 tgttgaaaaa tcctcgtgtt atcggtgtta agaactcttc tatgccagtt caagatatcc
    20041 aaacctttgt cagccttggt ggggaagacc atatcgtctt taatggtcct gatgagcagt
    20101 tcctaggagg acgcctcatg ggtgctaggg ctggtatcgg tggtacttat ggtgctatgc
    20161 cagaactctt cttgaaactc aatcagttga ttgcggataa ggacctagaa acagcgcgtg
    20221 aattgcagta tgctatcaac gcaatcattg gtaaactcac ttctgctcat ggaaatatgt
    20281 acggtgtcat taaagaagtc ttgaaaatca atgaaggctt gaatattgga tctgttcgtt
    20341 caccattgac accagtgact gaagaagatc gtccagttgt agaagcggct gctgccttga
    20401 ttcgtgaaac caaggagcgc ttcctctaat ctaaaaggag gtatttatga catactacgt
    20461 tgcaattgat atcggtggaa ccaacatcaa gtatggtttg gttgatcaag aggggcaact
    20521 tcttgaatcg catgaaatgc caactgaggc gcataagggt ggacctcata tcttacaaaa
    20581 gaccaaagat atcgtagcta gttatttaga aaaaggccca gtagcaggtg ttgccatatc
    20641 ttctgctggg atggtggatc cggataaggg tgagattttc tatgctgggc ctcaaatccc
    20701 taactacgca ggcacccagt tcaaaaagga aatcgaagaa agctttacta ttccttgtga
    20761 gattgaaaat gatgtcaact gtgcaggtct tgctgaggca gtatctggtt caggcaaggg
    20821 agcaagtgtg acactttgct tgaccattgg aaccggtatc ggtggttgct tgattatgga
    20881 taggaaagtc ttccatggtt ttagcaattc agcctgtgaa gtcgggtata tgcatatgca
    20941 ggatggagct tttcaggatc tcgcttctac aacagcttta gtgaaatatg tagctgaagc
    21001 ccatggagaa gatgttgatc agtggaatgg ccgacgtatc tttaaggaag ctactgaagg
    21061 aaacaaaatc tgcatggaag gtattgaccg tatggttgac tatctaggaa aaggtctggc
    21121 aaatatttgt tatgtggcca atccagaagt ggttattctt ggtggtggta tcatggggca
    21181 agaggctatc ctcaaaccta agatccgcac agccttgaaa gaggcattgg taccaagttt
    21241 agcagaaaaa acacgattag aatttgccca tcaccaaaat acagcaggga tgttgggtgc
    21301 atattatcat tttaagacaa aacaatccta gtttggctca gccaaactag gattttctta
    21361 cacgtttttg tctacgatag ccgttgagtt ttttattttc ccagtagcta ttaaagattt
    21421 tttccttgct ttcgcgattg atttccaaaa agtaggcata aatcaaatcg ataaagaaga
    21481 gcataggaag ttgagcggat attcgttgga tgtaggaggg ttggctgtgg gtggctacaa
    21541 gaacagtctc tgtataggtc tggctatctt tattgggaac acttgtaaag agtacagtct
    21601 ttgcccccat ctccttggca tctaatagac tatctaaaat agaaggagtt gagcctgaaa
    21661 gtgagaaacc cagtactaga caattttcat ccatgatgct ggttgtccag gcaaagccgt
    21721 cttggtctgt caaagcttcg cagaccacac ctagtcgcat aaaacgtaat ttcatttcac
    21781 gggcgacgag gccagaactc cctgttccaa agaagtagat acgctcagca tcttcgatta
    21841 gctgggcaat tcgctctagt tggatttcgt caatcaagtc ttgtgtttgt tccctcatat
    21901 tgctataact tctgaggact cgtttggtca gtggactatg cttggagact tggttggctt
    21961 gattttctgc ctgatgttgg tattggaaaa taaattctcg gtagccagta aagccacact
    22021 ttttagcaaa gcgggtcaaa gcagcttgag aaatatgtaa tttttgggtg acttgttgag
    22081 aagataaatc atctgtaatc gtttcagctt gcaaaaaata gcgagcgatt tcttgctcta
    22141 ggtctgtcat ttcttcaaaa tgtgaatcaa tgatagttgc gatatctggt ttgtccatag
    22201 ggaaagctcc tttacatggg tcatactgga agactagatc agggaatagt cacacttcat
    22261 tataacacat aatataagga tagataaata aaaacgcatc tctgttttaa aaacgaaaaa
    22321 atcgaaaaag cttctctctt ttccataatt ttctactcaa attgtggtac aattaagagt
    22381 aagattttaa gttagaaatg agactgattt gtatgagaaa atttaacagc cattcgattc
    22441 cgattcggct taatttattg ttttcaatcg tcattttact ctttatgacc attattggtc
    22501 gtttgttgta tatgcaggtt ttgaacaagg atttttacga aaaaaagcta gcctcagcta
    22561 gtcagaccaa gattacaagc agttcagccc gtggggaaat ttatgatgct agtggaaaac
    22621 ctttggtaga aaatacgtta aagcaggttg tttcctttac gcgtagcaat aaaatgacgg
    22681 ctacagactt aaaagaaaca gctaaaaagt tactgactta tgtgagcatc agttctccaa
    22741 atttgacaga acgccagctg gcggattact atttggctga tcctgaaatc tataaaaaaa
    22801 cagtggaagc tctcccaagt gagaaacgct tggattcaga tggcaatcgt ctatccgaat
    22861 cagaactgta taacaatgcg gtcgatagtg tccaaacaag tcaactaaac tatacagagg
    22921 atgaaaagaa agaaatctat ctttttagtc agttaaatgc tgttggaaac tttgcgacag
    22981 gaaccattgc tacagatcct ctaaatgatt ctcaggtggc tgttattgcc tctatttcaa
    23041 aggagatgcc tggcattagt atttctactt cttgggatag aaaggttttg gaaacttccc
    23101 tttcttctat agttgggagt gtatccagtg aaaaagctgg tctcccagcg gaagaagcag
    23161 aagcctatct taaaaaaggc tattctctaa atgatcgtgt aggaacctcc tatttggaaa
    23221 agcaatatga agagacctta caaggaaaac gctcggtaaa agaaatccat ctggataaat
    23281 atggcaatat ggaaagcgtg gatacaattg aggaaggtag taagggaaac aatatcaaac
    23341 tgaccattga tttggctttc caagatagcg tggatgcttt actgaaaagt tatttcaatt
    23401 ccgagctaga aaatggtgga gccaagtatt ctgaaggtgt ctatgcagtc gcccttaacc
    23461 caaaaacagg tgcggttttg tctatgtcag ggattaaaca tgacttgaaa acgggagagt
    23521 tgacgcctga ttccttggga acggtaacca atgtctttgt tccaggttcg gttgtcaagg
    23581 cggcgaccat cagctcaggt tgggaaaatg gagtcttgtc aggaaaccag accttgacag
    23641 accagtccat tgtcttccaa ggttcagctc ccatcaattc ttggtatact caggcttacg
    23701 gttcattccc tatcacagcg gtccaagctc tggagtattc atcaaatacc tatatggtcc
    23761 aaacagcctt aggtcttatg gggcaaacct atcaacccaa tatgtttgtc ggcaccagca
    23821 atctagagtc tgctatggag aaactgcgtt caacctttgg cgaatatggc ttgggtactg
    23881 cgacaggaat tgacctacca gatgaatcta ctggatttgt tcccaaagag tatagctttg
    23941 ctaattacat tactaatgcc tttgggcagt ttgataacta tacgccgatg cagttggctc
    24001 agtatgtagc aactattgca aataatggtg ttcgtgtggc tcctcgtatt gttgaaggca
    24061 tttatggtaa taatgataag ggaggactgg gtgacttgat tcagcaactg caaccgacag
    24121 agatgaataa ggtcaatata tccgactccg atatgagcat cttgcaccaa ggtttttatc
    24181 aggttgccca tggtactagt ggattgacaa ctggacgtgc cttttcaaat ggcgccttgg
    24241 tatccattag cggaaaaaca ggtacagccg aaagctatgt ggcagatggt cagcaagcaa
    24301 ccaataccaa tgcggtggcc tatgccccat ctgataatcc ccaaatcgct gttgcagtgg
    24361 tctttcctca taataccaat ctaacaaatg gtgtaggacc ttccattgcg cgtgacatta
    24421 tcaatctgta tcaaaaatac catccaatga actagaaagg aaattatgct ttatccaaca
    24481 cctattgcca agttgattga cagttattct aagttaccag gtatcgggat taagacggct
    24541 acgcgtctgg ccttttatac gattgggatg tctgctgatg atgtcaatga atttgcaaaa
    24601 aatctccttt ctgctaagag agaattgaca tattgttcta tttgtggacg tttgacagac
    24661 gacgatcctt gttctatctg tactgatccg actcgtgacc agacaacaat tttagttctt
    24721 gaggatagta gagatgtggc agccatggaa aatatccaag aataccatgg actctatcat
    24781 gtccttcatg gcctcatttc tcctatgaat ggtatcagtc cggacgatat caatctcaag
    24841 agccttatga ctcgtcttat ggatagtgaa gtttcagaag tgattgtggc gactaatgct
    24901 acagcggatg gtgaagcgac ttccatgtat ctttcacgtt tgctcaagcc ggctggtatc
    24961 aaggttacgc gtctagcacg aggtctcgct gtgggagcgg acattgagta tgcggacgaa
    25021 gtgacactct tacgagcgat tgaaaatcgg acagagttgt aagtgtaggc aaatttacga
    25081 actccattca tttataaaaa atcaaagagg ctgaaaatcg ttcctatcgg cctctttttg
    25141 tatagtgtga tgagtaggat caggttcaag ttttaaaaaa ccaagcaaat atgatatact
    25201 aaagagcgag tattctagta gaattaggac aaataatatg aaacaaacga ttattctttt
    25261 atatggtgga cggagtgcgg aacgcgaagt ctctgtcctt tcagctgaga gtgtcatgcg
    25321 tgcggtcaat tacgaccgtt tcacagtcaa gactttcttt atcagtcagt caggtgactt
    25381 tatcaaaaca caggaattta gtcatgctcc ggggcaagaa gaccgtctca tgaccaatga
    25441 aaccattgat tgggataaga aagttgcacc aagtgctatc tacgaagaag gtgcagtggt
    25501 ctttccagtc cttcacgggc caatgggaga agatggctct gttcaaggat tcttggaagt
    25561 tttgaaaatg ccttacgttg gttgcaacat tttgtcatca agtcttgcca tggataaaat
    25621 cacgactaag cgtgttctgg aatctgctgg tattgcccaa gttccttatg tggctatcgt
    25681 tgaaggcgat gatgtgactg ctaaaatcgc tgaagtggaa gaaaaattgg cttatccagt
    25741 cttcactaag ccgtcaaaca tggggtctag tgtcggtatt tctaagtctg aaaaccaaga
    25801 agaactccgt caagccttaa aacttgcctt ccgatatgac agccgtgtct tggttgagca
    25861 aggagtgaat gcccgtgaaa ttgaggttgg cctcttgggt aactacgatg tcaagagcac
    25921 gctacctgga gaagttgtca aggacgttgc cttttatgac tacgatgcca agtatattga
    25981 taacaagatt actatggata ttcctgccaa aatcagtgat gatgtggtgg ctgtcatgcg
    26041 tcaaaatgca gaaacagcct tccgtgccat tggtggcctt ggtctatctc gttgcgattt
    26101 cttctataca gataagggag agatttttct caacgagctc aataccatgc caggttttac
    26161 ccagtggtct atgtacccac tactttggga caatatgggg atcagctacc cagaactaat
    26221 cgagcgtttg gttgaccttg ccaaggaaag ttttgacaag cgcgaagcgc atttgatata
    26281 aaatgaaaga gagggtagaa gccagaacca tcactgcacg gtgactagag ttctcggact
    26341 tcagcccttt ttaaaggagt agaaatgaaa ttaacaatcc atgaaattgc ccaagttgtt
    26401 ggagccaaaa atgatatcag tatctttgag gacacccagt tagaaaaagc tgagtttgat
    26461 agtcgtttga ttggaactgg agatttattt gtgccactta aaggtgcgcg tgatggccat
    26521 gactttattg aaacagcctt tgaaaatggt gcagcagtaa ccttgtctga gaaagaggtc
    26581 tcaaatcatc cttacattct agtagatgat gttttgacag cctttcaatc cctagcatcc
    26641 tactatcttg aaaaaacgac tgttgatgtc tttgctgtta caggttcaaa tggcaagaca
    26701 acgactaagg atatgttggc gcatttactg tcaacaagat acaagaccta caaaacacaa
    26761 ggcaattaca ataatgagat tggccttcct tacacagttc ttcatatgcc tgaaggaaca
    26821 gaaaagttgg ttttggagat gggacaggat cacttgggag atattcatct cttgtctgaa
    26881 ttggctcgtc caaaaacagc catcgtgacc ttggttggag aagctcattt ggcctttttc
    26941 aaagatcgtt ctgagattgc taaaggaaaa atgcaaattg cagacggaat ggcttcaggt
    27001 tccttgcttt tagcgccggc tgaccctatc gtagaggact atttgccaac tgataaaaag
    27061 gtggttcgtt ttggtcaagg agcagagctg ggaattaccg acttggttga gcgcaaagat
    27121 agtctgacct tcaaggtcaa tttcttagag caagcccttg atttgccagt aactggcaag
    27181 tacaatgcga caaatgctat gattgcatcc tatgttgcct tgcaagaagg agtttcagag
    27241 gagcaaattc gtttggcctt ccaacatctt gaattgacgc gtaaccgtac cgagtggaag
    27301 aaagcagcca atggagcaga tatcctgtca gatgtttata atgccaatcc aactgctatg
    27361 aaactgattt tagagacttt ctctgccatt ccagccaatg aaggtggcaa gaaaattgca
    27421 gtgttggcgg atatgaagga gcttggtgac cagtctgttc aacttcataa tcagatgatt
    27481 ttgagcctct ccccagatgt gcttgatatc gttattttct atggagaaga tattgctcag
    27541 ttggctcaat tggccagtca aatgtttcca atcggccacg tttactactt caagaaaaca
    27601 gaagaccagg atcaatttga agacctagtc aagcaggtta aggaaagcct tggagcctat
    27661 gaccaaatct tgctaaaagg ttctaactct atgaatctag ccaaattggt agaacgttta
    27721 gaaaatgaag ccaagtgatt ttgtcaagta tctgcaaaga atgattgccc ttacagatac
    27781 tggcttaacc tttacaaaag atccttttga ccgtgagcgc tacgaggact tgcgaagtct
    27841 gttatctgaa atgttgaatc agggatcaga cctggatgca gaagaagtag cagaagtctt
    27901 gaaaccaact tcagcttatg cgactccctt aatggacgtc cgtgcttgga ttgttgagga
    27961 tgagaagatt tgtctggtta ggggacaagg agaggatagt tgggctttgc caggtggctt
    28021 tggtgaagtc ggctattctc caactgaaaa tattctcaag gaaattgaag aagaaaccgg
    28081 ttttaaagcc aaagttgaaa gactgctagc tgtttttgat accaatcgtt tccaactaca
    28141 gagtaaacaa tatgcaaagt ttgtttttga atgtaagttt ctcgatggac aattccaaga
    28201 aaatcaagaa attgcagacc ttcaattttt tgccattgat caactgccag ccttatctga
    28261 aaaacgcatt accaaggagc aaatcgagat tctttggcag gtttatcaag gtcagaggga
    28321 gcaatatctt gactaagaag atgattatcg tatttttaaa tccattttta acaactagca
    28381 tggtataata atatgcagga aaattttgaa ttatgaggaa gactagatga atttatggga
    28441 tattttcttt acgactcagg caaccgagcc gcccaaattt gacctttttt ggtatgttag
    28501 cctatttacg ctcttagcct taacctttta tacagcccat cgctatcgtg aaaagaaggt
    28561 ttaccaacga tttttccaaa tcttgcagac tgttcagtta atccttcttt atggttggta
    28621 ctgggtcaat catatgccac tgtcagaaag cctacccttt taccattgcc gtatggctat
    28681 gtttgtggta ctcttgcttc ctggtcagtc caaatataaa caatactttg cattattggg
    28741 aacatttggg acattagcag cctttgttta tccagtgcca gatgcttacc cttttccaca
    28801 tatcaccatt ctatccttta tctttggtca tttagcactc ttggggaact ctctagttta
    28861 tctattgaga cagtataatg cgcgattgct ggatgtgaag ggaatttttc tcatgacctt
    28921 tgccctaaat gccttgattt ttgtggtcaa tttggtgaca ggtggcgatt acggattttt
    28981 gacaaaaccg ccattggttg gggatcacgg tctagtagct aattatttac ttgtttcaat
    29041 tgtgctggta gctactatca gtttgactaa gaaaatctta gaattctttt tagctcaaga
    29101 agcagaaaaa atgattgcaa aggaagctta acacagagct ttcttttttg ctcttagaga
    29161 gtttttacaa gcagcttata aaataagaat ttctgaatag acaaactcaa aaaatggctg
    29221 ggaaatttag gaaaaaagca agcacgatta aattttttgt gttataatat tttgtgaata
    29281 gctatgccta tgtttagcta tggaataata cgaagtgcga aacttggaag atagagagga
    29341 agcgatgtaa tggctagaga aggctttttt acaggtctag atattggaac aagctctgtc
    29401 aaggtgcttg tggccgagca gagaaatggt gaattaaatg taattggcgt gagtaatgcc
    29461 aaaagtaaag gtgtaaagga tggaattatt gttgatattg atgcagcagc aactgctatc
    29521 aagtcagcca tttcccaagc ggaagaaaag gcaggcattt cgattaaatc agtgaatgtc
    29581 ggcttgcctg gtaatctttt gcaggtagaa ccaactcagg ggatgattcc agtaacatct
    29641 gatactaagg aaattacgga tcaagatgtt gaaaatgttg tcaaatcagc tttgacaaag
    29701 agtatgacac ctgaccgtga agtcattacc tttattcctg aagaatttat tgtggatggt
    29761 ttccaaggga ttcgtgaccc acgtggtatg atgggggttc gccttgaaat gcgtggtttg
    29821 ctttatacag gacctcgtac tatcttgcac aatttgcgta agacggttga gcgtgcaggt
    29881 gttcaggttg aaaatgttat catttcacca ctagcaatgg ttcagtctgt tttgaacgaa
    29941 ggggaacgtg aatttggtgc tacagtgatt gatatggggg caggtcaaac gactgtcgct
    30001 acaatccgta atcaagaact ccagttcaca catattctcc aagaaggtgg agattatgta
    30061 actaaagata tctccaaggt tttgaaaacc tctcgcaaat tagcggaagg cttgaaactg
    30121 aattacgggg aagcctatcc gcctcttgca agcaaagaaa ccttccaagt agaggttatt
    30181 ggagaagtgg aagcagtcga agtgacggaa gcctacttgt cagaaattat ttctgcacga
    30241 atcaagcaca tccttgaaca aatcaagcaa gaattagata gaaggcgtct attggacctc
    30301 cctggtggta ttgtcttaat cggtgggaat gccattttac caggtatggt tgagcttgct
    30361 caggaagtct ttggcgtccg tgtcaagctt tatgttccaa atcaagttgg tatccgtaat
    30421 ccagcctttg cgcatgtgat tagtttatca gaatttgcgg gtcaattaac agaagttaat
    30481 cttttggctc agggagcgat aaaaggtgag aatgacttaa gtcatcagcc aattagtttt
    30541 ggtgggatgc tgcaaaaaac agctcagttt gtacaatcaa cgcctgttca accagctcct
    30601 gctccagaag tagagccggt ggcgcctaca gaaccaatgg cggatttcca acaagcttca
    30661 caaaataaac cgaaattagc agatcgtttc cgtggcttga tcggaagcat gtttgacgaa
    30721 taaagaggaa aaataaatta tgacattttc atttgataca gctgctgctc aaggggcagt
    30781 gattaaagta attggtgtcg gtggaggtgg tggcaatgcc atcaaccgta tggtcgacga
    30841 aggtgttaca ggcgtagaat ttatcgcagc aaacacagat gtacaagcat tgagtagtac
    30901 aaaagctgag actgttattc agttgggacc taaattgact cgtggtttgg gtgcaggagg
    30961 tcaacctgag gttggtcgta aagccgctga agaaagcgaa gaaacactga cggaagctat
    31021 tagtggtgcc gatatggtct tcatcactgc tggtatggga ggaggctctg gaactggagc
    31081 tgctcctgtt attgctcgta tcgccaaaga tttaggtgcg cttacagttg gtgttgtaac
    31141 acgtcccttt ggttttgaag gaagtaagcg tggacaattt gctgtagaag gaatcaatca
    31201 acttcgtgag catgtagaca ctctattgat tatctcaaac aacaatttgc ttgaaattgt
    31261 tgataagaaa acaccgcttt tggaggctct tagcgaagcg gataacgttc ttcgtcaagg
    31321 tgttcaaggg attaccgatt tgattaccaa tccaggattg attaaccttg actttgccga
    31381 tgtgaaaacg gtaatggcaa acaaagggaa tgctcttatg ggtattggta tcggtagtgg
    31441 agaagaacgt gtggtagaag cggcacgtaa ggcaatctat tcaccacttc ttgaaacaac
    31501 tattgacggt gctgaggatg ttatcgtcaa cgttactggt ggtcttgact taaccttgat
    31561 tgaggcagaa gaggcttcac aaattgtgaa ccaggcagca ggtcaaggag tgaacatctg
    31621 gctcggtact tcaattgatg aaagtatgcg tgatgaaatt cgtgtaacag ttgtcgcaac
    31681 gggtgttcgt caagaccgcg tagaaaaggt tgtggctcca caagctagaa ctgctactaa
    31741 ctaccgtgag acagtgaaac cagctcattc acatggcttt gatcgtcatt ttgatatggc
    31801 agaaacagtt gaattgccaa aacaaaatcc acgtcgtttg gaaccaactc aggcatctgc
    31861 ttttggtgat tgggatcttc gccgtgaatc gattgttcgt acaacagatt cagtcgtttc
    31921 tccagtcgag cgctttgaag ccccaatttc acaagatgaa gatgaattgg atacacctcc
    31981 atttttcaaa aatcgttaag taaatgaatg taaaagaaaa tacagaactt gtttttcgag
    32041 aagttgcaga ggctagtctg agtgctcatc gagagagtgg ttcggtctct gtcattgcag
    32101 ttaccaagta tgtagatgta ccgacagcgg aagccttgct tccgctaggt gttcatcata
    32161 tcggtgaaaa tcgtgtagat aagtttctgg aaaaatatga agctttaaaa gatcgagatg
    32221 tgacttggca tttgattggt accttgcaaa gacgtaaggt gaaagatatc attcaatacg
    32281 ttgattattt ccatgcattg gactcagtaa agctagcagg ggaaattcaa aaaagaagtg
    32341 accgagtcat caagtgtttc cttcaagtaa atatttctaa agaagaaagc aaacacggtt
    32401 tttcgagaga ggaactgctg gaaatcttgc cagagttagc cagactagat aagattgaat
    32461 atgttggttt aatgacgatg gcaccttttg aggctagcag tgagcagttg aaagagattt
    32521 tcaaggcgac ccaagattta caaagagaaa ttcaagagaa acaaattcca aatatgccta
    32581 tgaccgagtt aagtatggga atgagtcgtg attataaaga agcgattcaa ttcggttcca
    32641 cttttgttcg tataggtaca tcatttttta agtaggagag aaccatgtct ttaaaagata
    32701 gattcgatag atttatagat tattttacgg aggatgagga ttcaagtctc ccttatgaaa
    32761 aaagagatga gcctgtgttt actccagtaa attcttcaca ggaaccggct ctcccaatga
    32821 atcaaccttc acagtcggct ggtacaaaag agaacaatat caccagactt catgcaagac
    32881 aacaggaatt ggcaaatcag agtcagcgtg caacggataa ggtcattata gatgttcgtt
    32941 atcctagaaa atatgaggat gcaacagaaa ttgttgattt attggcagga aacgaaagta
    33001 tcttgattga ttttcagtat atgacagagg tgcaggctcg tcgttgtttg gactatttgg
    33061 atggagcttg tcatgtttta gctggaaatt tgaaaaaggt agcttctacc atgtatttgt
    33121 tgacaccagt gaatgttatt gtaaatgttg aagatatccg tttaccagat gaagatcaac
    33181 agggtgagtt cggttttgat atgaagcgaa atagagtacg ataatgattt ttttaattcg
    33241 tatgatttat aatgcagtgg atatttactc cctgattttg gtagccttcg ctgtcatgtc
    33301 ttggtttcca ggtgcctacg aatccagttt aggtcgttgg attgtagcgt tggtgaaacc
    33361 agtgcttgct cccttgcaac gcctgccttt acagatagcg ggtcttgatt tatctgtttg
    33421 ggtcgcgatt gttttggttc gatttttagg agaaaaccta gtgcgttttc tggcgatgat
    33481 aggatgaata aagggattta tcagcatttc tccatagaag atcgtccatt tcttgacaag
    33541 ggaatggaat ggataaagaa ggtagaagat agctatgctc cttttttaac tccttttatc
    33601 aatcctcatc aggagaagct attaaagatt ttggccaaaa cctatggtct tgcttgtagc
    33661 agtagtgggg aattcgtctc gagtgagtat gttcgagttt tattataccc agattatttc
    33721 caaccagagt tttcagattt tgaaatatct ctccaggaaa ttgtgtattc caataaattt
    33781 gaacatttaa cgcatgctaa gattttaggg acagtcatca atcaattagg gattgaacgg
    33841 aaactttttg gagatatcct agtagatgaa gaacgggcgc agattatgat taatcagcag
    33901 tttcttcttc tctttcaaga tggactaaag aaaattggtc gtatacctgt ttcgctggag
    33961 gaacgtcctt tcaccgagaa aatagataag ctagaacagt atcgagaact ggatttatct
    34021 gtgtctagtt ttcgattaga tgttctttta tcaaatgttt tgaaactatc taggaatcaa
    34081 gcaaaccagt tgattgaaaa gaaacttgtc caagtaaatt atcatgtggt agacaaatca
    34141 gattacactg ttcaagttgg agacttgatt agtgtgagaa aatttggtcg cttgagatta
    34201 cttcaagata agggacaaac gaaaaaagag aagaaaaaaa taaccgtcca gttattatta
    34261 agtaagtgag gaatagaatg ccaattacat cattagaaat aaaggacaag acttttggaa
    34321 ctcgattcag aggttttgat ccagaagaag tcgatgaatt tttagatatt gtggttcgtg
    34381 attacgaaga tcttgtgcgt gcgaatcatg ataaaaattt gcgtattaag agtttagaag
    34441 agcgtttgtc ttactttgat gaaataaaag attcattgag ccagtctgta ttgattgctc
    34501 aggatacagc tgagagagtg aaacaggcgg cgcatgaacg ttcaaacaat atcattcatc
    34561 aagcagagca agatgcgcaa cgcttgttgg aagaagctaa atataaggca aacgagattc
    34621 ttcgtcaagc aactgataat gctaagaaag tcgctgttga aacagaagaa ttgaagaaca
    34681 agagccgtgt cttccaccaa cgtctcaaat ctacaattga gagtcagttg gctattgttg
    34741 aatcttcaga ttgggaagat attctccgtc caacagctac ttatcttcaa accagtgatg
    34801 aagcctttaa agaagtggtt agcgaagtac ttggagaacc gattccagct ccaattgaag
    34861 aagaaccaat tgatatgaca cgtcagttct ctcaagcaga aatggaagaa ttacaagctc
    34921 gtattgaggt agccgataaa gaattgtctg aatttgaagc tcagattaaa caggaagtgg
    34981 aaactccaac tcctgtagtg agtcctcaag ttgaagaaga gcctctgctc atccagttgg
    35041 cccaatgtat gaagaaccag aagtagctcc agtgcatccg acaggtccaa caccagctac
    35101 agaaactgtt gattcagcac caggatttga agcaccgcaa gaatccgtta caattttata
    35161 agaaacgatg tgagaacaat atcttatcct tatatttcca gcgagcagga gatggtgtga
    35221 gtcctgcatt ccctaacgat aagattatcc tctcaaaaac tcaagtctga atctagtaag
    35281 atttgacgtt tcccacgtta cgggataaga gggagaaaga ctaaatcttt ttccgaataa
    35341 aggtggtacc acgattttcg tcctttttgg aagtcgtggt ttttaatttg ttattattta
    35401 taaaggagat accatgaaac taaaagatac ccttaatctt gggaaaacag ctttcccaat
    35461 gcgtgcaggc cttccgacca aagagccagt ttggcaaaag gaatgggaag atgcaaaact
    35521 ttaccaacgt cgtcaagaac taaatgaagg gaaaccgcat tttgtcttgc atgatggccc
    35581 tccatacgca aacggaaata tccacgttgg acatgccatg aatcatatct caaaagatat
    35641 catcattcgt tctaagtcta tgtcaggttt taacgcacct tatatcccag gttgggatac
    35701 tcatggtctg ccaatcgagc aagttttggc aaagcaaggt gtgaagcgca aagaaatgga
    35761 cttggttgag tacttgaaac tttgccgtga atacgctctt tctcaagttt ataaacaacg
    35821 tgatgatttc aagcgcttgg ggatgtcagg tgactgggaa aatttatatg tgactttaac
    35881 tccagactac gaagcagccc aaatccgtgt atttggtgag atggctaata agggttatat
    35941 ctaccgtggt gctaagccag tttactggtc ttggtcatct gagtcagccc ttgccgaagc
    36001 ggaaattgaa taccatgatt tggtttcaac ttccctttac tatgccaata aggtaaaaga
    36061 tggcaaaggt gttctagata cagatactta tatcgttgtt tggacaacta ctccatttac
    36121 tatcacagct tctcgtggtt tgactgttgg tgcagatatt gattacgttt tggttcaacc
    36181 tgctggtgaa actcgtaagt ttgtcgttgc tgcagaattg ttgactagct tgtctgagaa
    36241 atttggctgg gttgatgttc aagttttggc aacttaccgt ggtcaagaac tcaaccacat
    36301 cgtaacagaa catccatggg atacagctgt agatgaattg gttatccttg gtgaccacgt
    36361 tacaactgac tctggtacag gtattgtcca tacagcccct ggttttggtg aggacgatta
    36421 caatgttggt attgctaata atcttgaagt cgcagtgact gttgatgaac gtggtatcat
    36481 gatgaagaat gctggtcctg aatttgaagg tcaattctat gaaaaggtag ttccaactgt
    36541 tattgaaaaa cttggtaacc tccttcttgc ccaagaagaa atctctcact catatccatt
    36601 tgactggcgt accaagaaac caattatctg gcgtgcagta ccacagtggt tcgcctctgt
    36661 ttcaaaattc cgccaagaaa tcttggatgc tattgataaa gttaaattcc atacagaatg
    36721 gggtaaagta cgtctatata atatgattcg tgaccgtggt gactgggtta tctctcgtca
    36781 acgtgcttgg ggtgttccac ttccaatctt ctatgcagaa gacggtacag ctatcatgac
    36841 agctgagact atcgaatatg tggctcaact ctttgaagta catggttcaa gcatttggtg
    36901 ggaacgtgat gccaaagacc tcttgccaga aggatttaca catccaggtt ctccaaatgg
    36961 cgagttcaaa aaagaaactg atatcatgga cgtttggttt gactcaggtt catcatggaa
    37021 tggtgttttg gtaaatcgtc caaatctgac ttatccagct gacctttacc ttgaaggttc
    37081 tgaccaatac cgtggttggt tcaactcatc actcattaca tctgttgcca accatggcgt
    37141 agcaccttac aaacaaatct tgtcacaagg ttttaccctt gacggtaaag gtgagaagat
    37201 gtctaaatct cttggaaata ccattgctcc aagcgatgtt gaaaaacaat ttggtgctga
    37261 aatcttgcgt ctctgggtaa caagtgttga ctcaagcaat gacgtgcgta tctctatgga
    37321 tatcttgagc caagtctctg aaacttaccg taagattcgt aatactcttc gtttcttgat
    37381 tgccaataca tctgacttta acccaactca agatgcagtc gcttacgatg aacttcgttc
    37441 agttgataag tacatgacca ttcgctttaa ccagcttgtc aagaccattc gtgatgccta
    37501 tgcaaacttt gaattcttga caatctacaa ggccttggtg aactttatca acgttgattt
    37561 atcagccttt taccttgatt ttgctaaaga tgttgtttac atcgaaggtg ctaaatcact
    37621 ggaacgtcgt caaatgcaga ctgtcttcta tgatattctt gtcaaaatca ccaaactctt
    37681 gacaccaatc cttcctcaca ctgcggaaga aatctggtca tatcttgagt ttgaaacaga
    37741 agacttcgtc caattgtcag aattaccaga agttcaaact tttgctaacc aagaagaaat
    37801 cttggataca tgggcagcct tcatggactt tcgtggacaa gcacaaaaag ccttggaaga
    37861 agctcgtaat gcaaaagtta tcggtaaatc acttgaagca cacttgacag tttatccaaa
    37921 tgaagtggtg aaaactctac tcgaagcagt aaatagcaat gtggctcaac ttttgatcgt
    37981 gtctgagttg accatcgcag aaggaccagc tccggaagct gcccttagct tcgaagatgt
    38041 agccttcaca gttgaacgtg ctgctggtga agtatgtgac cgttgccgtc gtattgaccc
    38101 aacaacagca gaacgtagct accaggcagt tatctgtgac cactgtgcaa gcatcgtaga
    38161 agaaaacttt gcggaagcag tcgcagaagg atttgaagag aaataagatt gaaaagtcta
    38221 ggcaaaattc aatttgagaa gaaaagacaa ctaattttat agtctattaa acgcattgta
    38281 tcacgttttt gaacacctga tatgatgcgt tttttattta ttttaaaaat ttgcgaggta
    38341 tgacttttta tactcaacaa gaatcaaaga gaaacttagc aagctaacag tagtaagata
    38401 aaataggaat ttgatattag ggataagatt gg
//
LOCUS       DAVLBN010000015        36709 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLBN010000015 DAVLBN010000000
VERSION     DAVLBN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.015"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            148..1377
                     /gene="arcA"
                     /locus_tag="VXC24_000749"
     CDS             148..1377
                     /gene="arcA"
                     /locus_tag="VXC24_000749"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0492897.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            1435..2451
                     /gene="argF"
                     /locus_tag="VXC24_000750"
     CDS             1435..2451
                     /gene="argF"
                     /locus_tag="VXC24_000750"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0492898.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            2616..3563
                     /gene="arcC"
                     /locus_tag="VXC24_000751"
     CDS             2616..3563
                     /gene="arcC"
                     /locus_tag="VXC24_000751"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0492899.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            3774..5285
                     /locus_tag="VXC24_000752"
     CDS             3774..5285
                     /locus_tag="VXC24_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0492900.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            5307..6638
                     /locus_tag="VXC24_000753"
     CDS             5307..6638
                     /locus_tag="VXC24_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0492901.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            6733..6860
                     /locus_tag="VXC24_000754"
                     /pseudo
     CDS             6733..6860
                     /locus_tag="VXC24_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(7025..7315)
                     /locus_tag="VXC24_000755"
     CDS             complement(7025..7315)
                     /locus_tag="VXC24_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492902.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(7303..7554)
                     /locus_tag="VXC24_000756"
     CDS             complement(7303..7554)
                     /locus_tag="VXC24_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0492903.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(7908..8792)
                     /locus_tag="VXC24_000757"
     CDS             complement(7908..8792)
                     /locus_tag="VXC24_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0492904.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(8937..10088)
                     /locus_tag="VXC24_000758"
     CDS             complement(8937..10088)
                     /locus_tag="VXC24_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0492905.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(10234..12000)
                     /locus_tag="VXC24_000759"
     CDS             complement(10234..12000)
                     /locus_tag="VXC24_000759"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0492906.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(12057..15173)
                     /locus_tag="VXC24_000760"
     CDS             complement(12057..15173)
                     /locus_tag="VXC24_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0492907.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAISEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(15183..17477)
                     /locus_tag="VXC24_000761"
     CDS             complement(15183..17477)
                     /locus_tag="VXC24_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0492908.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRV
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(17536..18336)
                     /locus_tag="VXC24_000762"
     CDS             complement(17536..18336)
                     /locus_tag="VXC24_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0492909.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(18333..19106)
                     /locus_tag="VXC24_000763"
     CDS             complement(18333..19106)
                     /locus_tag="VXC24_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0492910.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(19131..19601)
                     /locus_tag="VXC24_000764"
     CDS             complement(19131..19601)
                     /locus_tag="VXC24_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0492911.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(19592..20023)
                     /locus_tag="VXC24_000765"
     CDS             complement(19592..20023)
                     /locus_tag="VXC24_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0492912.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(20016..20456)
                     /locus_tag="VXC24_000766"
     CDS             complement(20016..20456)
                     /locus_tag="VXC24_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0492913.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(20468..21106)
                     /locus_tag="VXC24_000767"
     CDS             complement(20468..21106)
                     /locus_tag="VXC24_000767"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0492914.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(21221..22624)
                     /locus_tag="VXC24_000768"
     CDS             complement(21221..22624)
                     /locus_tag="VXC24_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0492915.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELNSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            22800..23573
                     /locus_tag="VXC24_000769"
     CDS             22800..23573
                     /locus_tag="VXC24_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0492916.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(24744..26249)
                     /gene="adcA"
                     /locus_tag="VXC24_000770"
     CDS             complement(24744..26249)
                     /gene="adcA"
                     /locus_tag="VXC24_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0492917.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(26259..27065)
                     /locus_tag="VXC24_000771"
     CDS             complement(26259..27065)
                     /locus_tag="VXC24_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0492918.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(27058..27762)
                     /locus_tag="VXC24_000772"
     CDS             complement(27058..27762)
                     /locus_tag="VXC24_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0492919.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(27762..28202)
                     /gene="adcR"
                     /locus_tag="VXC24_000773"
     CDS             complement(27762..28202)
                     /gene="adcR"
                     /locus_tag="VXC24_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0492920.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(28357..29625)
                     /gene="dltD"
                     /locus_tag="VXC24_000774"
     CDS             complement(28357..29625)
                     /gene="dltD"
                     /locus_tag="VXC24_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0492921.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(29618..29857)
                     /gene="dltC"
                     /locus_tag="VXC24_000775"
     CDS             complement(29618..29857)
                     /gene="dltC"
                     /locus_tag="VXC24_000775"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0492922.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(29871..31115)
                     /gene="dltB"
                     /locus_tag="VXC24_000776"
     CDS             complement(29871..31115)
                     /gene="dltB"
                     /locus_tag="VXC24_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0492923.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(31112..32662)
                     /gene="dltA"
                     /locus_tag="VXC24_000777"
     CDS             complement(31112..32662)
                     /gene="dltA"
                     /locus_tag="VXC24_000777"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0492924.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(32683..32814)
                     /locus_tag="VXC24_000778"
     CDS             complement(32683..32814)
                     /locus_tag="VXC24_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0492925.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(33128..34306)
                     /locus_tag="VXC24_000779"
     CDS             complement(33128..34306)
                     /locus_tag="VXC24_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0492926.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(34758..36034)
                     /gene="ltrA"
                     /locus_tag="VXC24_000780"
                     /pseudo
     CDS             complement(34758..36034)
                     /gene="ltrA"
                     /locus_tag="VXC24_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        11185 a         7754 c         6342 g        11428 t
ORIGIN      
        1 aataacataa aattgtgcta aatattataa tttatattat tttccgagaa attatagcca
       61 ttgacattac ctaggaattg cgttataaca tacatgtaag cggtacccaa aatggtgcca
      121 agtcaaaatt tttaaggagg aaaatacatg tcttcacatc caattcaggt cttctcagaa
      181 attgggaaac tgaaaaaagt tatgttacac cgtccaggca aggagttaga aaacttgttg
      241 ccggactatc ttgaaaggct tctttttgat gatattcctt tcttggaaga tgctcaaaaa
      301 gaacatgatg catttgccca agctcttcgc gatgaaggaa ttgaggttct ctacctagaa
      361 caactcgctg ctgaatcatt gacctctcca gaaatccgcg atcaatttat cgaggaatac
      421 ttagacgaag ccaacatccg tgatcgtcaa accaaggttg ctattcgtga attgcttcac
      481 ggcatcaagg acaaccaaga attggttgaa aaaacaatgg ctgggattca aaaagttgaa
      541 ttgccagaaa ttcctgacga agctaaagat ctaactgact tagttgaatc agattatcca
      601 tttgcaattg acccgatgcc aaacctctat ttcactcgcg acccatttgc aacaattgga
      661 aacgccgtat cgcttaacca catgtttgca gacactcgta accgtgaaac actctacggt
      721 aagtatatct tcaaatacca cccaatctat ggcggaaaag tggatttggt ctacaaccgt
      781 gaagaagata cgcgtatcga aggtggagac gagctagttc tttctaaaga cgtccttgca
      841 gtaggtatct ctcaacgtac agacgcagct tctatcgaaa aacttttggt caacatcttc
      901 aagaaaaatg ttggcttcaa gaaagttttg gcctttgaat ttgctaacaa ccgtaaattc
      961 atgcacttgg atactgtctt cactatggta gactatgaca agttcactat tcacccagaa
     1021 atcgaaggcg accttcacgt ttactcagtt acttacgaaa acgaaaaact taaaatcgtt
     1081 gaagagaaag gtgacttagc tgaacttctt gctcaaaacc ttggtgtaga aaaagttcat
     1141 ttgattcgtt gcggtggtgg caatatcgta gcagctgcgc gtgaacaatg gaacgacggt
     1201 tctaacactt tgaccatcgc acctggtgtg gtagttgttt atgaccgcaa taccgtgacc
     1261 aataagattt tggaagaata cgggcttcgc ttgattaaga ttcgcggaag tgaattggtt
     1321 cggggccgtg gtggacctcg ttgtatgtct atgccatttg aacgtgaaga agtgtaatcg
     1381 ctgttcggca ttcgtcaata gaaaatgtaa aaaatagaaa gaggaaataa taaaatgaca
     1441 aattcagtat tccaaggacg cagcttctta gcagaaaaag actttacccg tgcagagtta
     1501 gaatacctta ttggtctttc agctcacttg aaagatttga aaaaacgcaa tattcaacac
     1561 cactaccttg ctggcaagaa tatcgctctc ctatttgaaa aaacatctac tcgtactcgt
     1621 gcagccttta caactgcggc tatcgacctt ggtgctcacc cagaatacct cggagcaaat
     1681 gatattcagt tgggtaaaaa agaatctact gaagatactg ctaaagtatt gggacgtatg
     1741 tttgacggga ttgaattccg cggattcagc caacgtatgg ttgaagaatt ggcagaattc
     1801 tcaggcgttc cagtatggaa cggtctaact gacgaatggc acccaactca aatgctcgct
     1861 gactacttga ctgttcaaga aaacttcggt cgcttggaag gcttgacatt ggtatactgt
     1921 ggtgatggac gtaacaacgt tgccaacagc ttgctcgtaa caggtgctat ccttggtgtc
     1981 aatgttcaca tcttctcacc aaaagaactc ttcccagaaa aagaaatcgt tgaattggca
     2041 gaaggatttg ctaaagaaag tggcgcacat gttctcatca ctgaagatgc tgatgaagca
     2101 gttaaagatg cagacgttct ttacacagac gtttgggtat caatgggtga agaagacaaa
     2161 ttcgcagaac gtgtagctct tcttaaacct taccaagtca atatggactt agttaaaaaa
     2221 gcaggcaatg aaaacttgat cttcctacac tgcttgccag cattccacga tactcacact
     2281 gtttatggta aagacgttgc tgaaaaattt ggtgtagaag aaatggaagt aacagacgaa
     2341 gtcttccgca gcaagtacgc tcgccacttc gatcaagcag aaaaccgtat gcacactatc
     2401 aaagctgtta tggctgcgac acttggtaac ctttatattc ctaaagtata attttagata
     2461 ataaaccgtc taccaacagc tatgagggct gcgactaata gctttagtcc ggtcctcttt
     2521 tatgtaatgg taatctatta tttcttataa aatatgtgaa aaatcattaa attgaaatct
     2581 aaacgcattc tattgagtgt gataaaggag aatttatggc aaatcgtaaa attgtagtag
     2641 ctttgggagg aaatgcgatt ctttcttctg acccatcagc aaaggctcaa caagaagctt
     2701 tagttgaaac agctaagcat cttgtaaaat tgattaaaaa tggagatgat ctgattatca
     2761 ctcacggtaa tggacctcaa gttgggaatc tcttgctcca acatttggca tcagactctg
     2821 aaaagaaccc tgccttccca ctcgactcac ttgtcgctat gacagaaggt agcatcggtt
     2881 tctggttgaa aaatgctttg caaaatgctc tcttggatga aggcatcgaa aaaaacgttg
     2941 cctctgttgt aacgcaagtt gtcgtagata aaaatgatcc agcttttgtt aacttgagta
     3001 aaccaatcgg tcctttctat tcagaagaag aagcaaaagc agaagccgaa aagagcggag
     3061 cgactttcaa ggaagatgct ggccgtggct ggcgtaaggt cgttgcctca ccaaaacctg
     3121 ttgacatcaa agaaattgaa accatccgta ctcttttaaa tagtggtcaa gtcgtcgtag
     3181 ctgcaggtgg tggcggtatt cccgtcgtca aagaaaacaa tggacatttg actggtgtcg
     3241 aagcggttat tgataaagac ttcgcttccc aacgtttggc agaattggtt gatgcagacc
     3301 tcttcatcgt tttgacaggt gtagattatg tatttgttaa ctacaacaag ccaaaccagg
     3361 aaaaattgga acatgtgaat gttgcccagc tggaagaata tatcaaacaa gatcagtttg
     3421 caccaggtag catgcttcca aaagtagaag cagctatcgc ttttgtcaat ggtcgtccag
     3481 aaggaaaagc agttattact tcccttgaaa atctaggcgc cttgattgaa tctgaaagtg
     3541 gaacaattat tgaaaaagga taagttgttt tactaataag atgtattcta tttctagtat
     3601 ctttatatca aattagaaat tattcttgaa aacatgtaca atatttcaaa agatattagt
     3661 tttttagact ttaatatggt aaaacaaata taaatagaaa gcgttttctt aaatgtttat
     3721 ttaagaaagt agttggtttt ttacactttg ttagacatca ggaggaaaaa caaatgagtg
     3781 aaaaagctaa aaaagggttt aagatgcctt catcttacac cgtattattg ataatcattg
     3841 ctattatggc agtactaact tggtttatcc ctgcgggggc ctttatagaa ggtatttacg
     3901 agactcagcc tcaaaatcca caagggattt gggatgtcct catggcacca attcgggcta
     3961 tgctaggtac tcatccagag gaaggttcgc tcattaaaga aacgagcgca gcgattgatg
     4021 tagccttctt catccttatg gttggtggtt tccttggcat tgtcaacaaa actggtgctc
     4081 ttgacgtagg gattgcctct atcgtgaaga agtataaggg ccgcgaaaaa atgttaattt
     4141 tggtactaat gcctttgttt gccctcggtg gtacaactta tggtatgggt gaagaaacaa
     4201 tggccttcta tccactcctt gtgccagtta tgatggccgt tggttttgat agcctgactg
     4261 gtgttgcaat tattttgctc ggttctcaaa tcggctgttt ggcatctact ctgaatccat
     4321 ttgcgacagg tattgcttca gcgactgcgg gagttggtac aggggacggt atcgtacttc
     4381 gtctgatctt ctgggttacc ttgactgctc ttagtacttg gtttgtttac cgttatgcgg
     4441 ataagattca aaaagatccg actaagtcac tggtttatag tactcgcaaa gaagatttga
     4501 aacactttaa cgtagaagaa tcttcatctg tagaatctac acttagcagc aaacaaaaat
     4561 cagttctctt cttatttgtg ttgacattca tcttgatggt attgagcttc attccatgga
     4621 cagaccttgg cgttaccatt tttgatgact ttaatgcttg gttgactggt cttccagtta
     4681 ttggtaatat tgtcggttca tctacttctg cactaggtac ttggtacttc ccagaaggcg
     4741 caatgctctt tgcctttatg ggtatcctga ttggtgttat ttatggtctt aaagaagata
     4801 agattatctc ttccttcatg aatggtgctg ctgacttgct cagtgttgcc ttgatcgtag
     4861 cgattgctcg tggtattcaa gttatcatga acgacggtat gattaccgat acaatcctca
     4921 actggggtaa agaaggcttg agcggtctat cttcacaagt ctttatcgtt gtaacttata
     4981 tcttctatct acctatgtca ttcttgatcc catcttcatc tggtcttgcc agcgcaacta
     5041 tgggtatcat ggctccactt ggagaatttg taaatgtccg tcctagcttg attatcactg
     5101 cttatcaatc tgcttcaggt gtcttgaact tgattgcacc aacatctggt attgtgatgg
     5161 gagctcttgc acttggacgt atcaacattg gtacttggtg gaaattcatg ggcaaactcg
     5221 tagtcgctat tattgtagtg accatcgccc ttcttctcct tggaaccttc cttccattcc
     5281 tataaaatag tgagtgaggt gattccatga aaatagatat aacaaatcaa gttaaagatg
     5341 aatttcttat atcattaaaa accttgattt cctatccttc agtactcaat gaaggagaaa
     5401 atggaacacc ttttggacaa gcaatccaag atgtcctaga aaaaacttta gagatttgtc
     5461 gagacatagg tttcactacc tatcttgacc ctaaaggtta ttacggatat gcagaaatcg
     5521 gtcagggagc agagcttctg gccattctct gtcatttgga tgttgttcca tcaggtgatg
     5581 aagcagattg gcagacaccg ccatttgaag caactatcaa agacggctgg gtattcggac
     5641 gtggtgtcca agatgataaa ggcccttcgc tcgcagctct ctatgcagta aaaagcttgc
     5701 tggaccaagg tattcagttc aaaaagcgcg tacgctttat ctttggtacc gatgaggaaa
     5761 acctctggcg ctgcatggca cgctacaata ccatcgaaga acaggccagt atgggctttg
     5821 cacctgactc atcttttcct ctgacctatg ctgaaaaagg gcttctacag gtcaaacttc
     5881 atggcccggg atcggatcaa ctagagcttg aagtaggagg cgcctttaac gttgtaccag
     5941 acaaggccaa ctaccaaggt cttctctatg aacaggtttg taacggtctc aaagaagctg
     6001 gttatgatta ccaaaccact gaacaaaccg taacggttct cggagtgcca aagcatgcta
     6061 aggatgctag tcaaggtatc aatgctgtca tccgactagc taccattctt gctcctctcc
     6121 aagaacaccc tgctctcagt tttcttgcaa cacaagcagg tcaagacggc acaggaagac
     6181 aaatctttgg tgatatagca gatgaacctt ctggtcacct atcctttaat gtcgcaggtc
     6241 tcatgatcaa tcatgaacgt tctgaaatcc gtattgacat tcggactcct gtcttagctg
     6301 acaaggaaga actagtagag ttgcttacaa gatgtgcaca aaactaccaa ctccgctacg
     6361 aagagtttga ctatctagcg cctctatacg tcgcaaaaga cagtaaactc gttagcacac
     6421 tgatgcaaat ctaccaagaa aagactggcg ataacagtcc tgctatttca tccggtggtg
     6481 ccacttttgc tcgcaccatg ccaaattgtg tagccttcgg cgccttattc ccaggagcga
     6541 agcagacaga acatcaggca aatgaatgtg ccgttctaga agatttgtac cgtgctatgg
     6601 atatttatgc cgaagccgtc tatcgacttg caacttaatc aggcaactgt ttctacaaaa
     6661 aaaaatcgac cgattaatga actgcacccc aaaagttaga cagaataaat ctaacttttg
     6721 gggtgtttta ttatgaaatt gaattatgaa gataaagttc agatctatga actaagaaag
     6781 caaggacaaa gcttcaaaca gctttcaaaa agatttatgt ggatgtttct ggtttaaagt
     6841 catctgaatc tttgagatga gctttataaa tcgctttttt cagtgtttgc actggtgttt
     6901 cgataaactc aaacttttta gccgtggtat tgcctgattt tatagtatat tgaaactaga
     6961 atagtacacc tctacttcta aaacattttt agaaatcgat ttgtcctgtt cttatttcat
     7021 tttactatat ttgagccact tcgtctttaa cggctttatt cataagctct tgtaattttt
     7081 ctttactatc aattacttct gattttccgt tgtaatttat tgtaataggt tttaacttac
     7141 ctaatttctc gacacgctca ttaatttgat cttttttgaa ggctgcatat gtttttccta
     7201 agattttttc gaaaatatat ttatcagata gcggtttgcc ttcttcttca gcttggtttt
     7261 tgtattgatt tgaaacataa ggaacaaatc cttcatagta acctaatgct cccataagtt
     7321 caaaagcttg ttttctaatt caaaccattg caactcagat ttcagctttt cagataaatc
     7381 ctgctcatcc aaataatgac ttaaaattag tgctgaactc gtttctgtat cctgtacagg
     7441 ctgatcaccc ataccatcaa aaaataaact cgttcctagc aagaccgaac aagctcctat
     7501 tgcatatggc ctcaaagaaa aacgctgctt tctctcaaat tgaaattctt tcatcccatc
     7561 tcccatcatt cattattact gtatattttg tatatcagaa atagtttgta ttcacaaatc
     7621 tttctagtta ttcccttatc attcctaatt aagggagata acatacaata atttttagtt
     7681 aaatgtatat cgatgttttt tgtttttctt aataaacgca atacaaaaag agcctgttgc
     7741 caagctcttt gtactcaatg aaaatcaaag agcaaactag gaaactagcc acaggttgct
     7801 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaacatc tatacggcaa
     7861 ggcgacgctg acgtggtttg aagagatttt cgaagagtat tagtctatta tttcttctca
     7921 gcgcgaaggg ctgacaagat ttgtgttcgg atatcatcca caccatttgg agtatttggt
     7981 aaaaagatgg tttgatttcc tttagaggca aaggtattca aggtatccaa atactggttg
     8041 gtcaagagga tagacatgat ttgttcttct gtcatgccaa cattggcttc cttgagttcg
     8101 gtgatagact ctgccaatcc atccacaatc gccttacgtt gttgggcaat ccccacacca
     8161 tgaaggcggt ctttttctgc ttcggcttca gctgcagtga caattttaat cttgtcagct
     8221 tccgccaatt cttgtgctgc gacccgctta cgttgcgccg cattgatttc attcatggat
     8281 tgcttaactt ctgcatccgg ttcgactttg gtaatcaagg ttttcacgat aatgtagccg
     8341 taagtggtca tttcttctgc tacttggtgt tgaacctcaa gggcaatctc atcttttttc
     8401 tcaaacaatt catccaaggt taattttgga acagaagagc gaagagcatc ttcgatataa
     8461 gatttaatct gagattctgg acgtatgagt ttatagtaag catctgtcac gctctgctcg
     8521 ttgacacggt actgagtcgc tacattcatc ataacgaaca cattgtcctt ggtcttagtc
     8581 tcaaccacaa tatcactttg caacaagcgc aactgaatcc gtgctgcaat cgagtcaatc
     8641 ccaaaaggca agcgaatatg aataccgcta ttagcaacct tttggtattt cccaaagcgt
     8701 tcaataatcg ccaccgactg ctgacgaacc acataaactg tactcagtgt gactatcacc
     8761 aataggagca cacaaacaat cagaaaaatc atgaaaaata ttgccataat ggaacctcca
     8821 caagtatttt tctagtatta tagcacattt aaagaaggct gtgccgtttt tactgcgatt
     8881 tttcctgaaa tgtcaataat tagaggtgaa ttgtcctatt gtcgtccaat ctcttgctaa
     8941 aataactctt tataaaaggc aatcgtttct tctaaggttg gcataaatgg atttcctggt
     9001 gcgcaggcat caatcaaggc attcttagaa aggtattcaa agtcgaaatc tttttcttca
     9061 ataccaagtt cagtcagttt cttaggaata cctactgtct cagaaagctt ctcaatctca
     9121 acaatcgcat aatcggcaca ttcttgatct gatttacctt ctacatgaag tcccaaggct
     9181 ttggcaacat tgcggaaagc ttctggtaca cgtttagcat tttcacgttc tataactggt
     9241 agcaacatgg cacagcaaac accatgtggc aaattatata ctgcaccgag ttggtgagcc
     9301 attgagtgaa cataaccaag accagcatta ttaaagctca taccaccaag gaagatggca
     9361 ttgaccatac cttcacgcgc ttcaatatca tgtccatttt ctacagcacg aggaagatat
     9421 tccttgataa gctcaatagc accaatagac agtttcttgg ttacatcata agcaccaggt
     9481 gttaccaaag cttcaacagc gtgagtcaga gcatccatac cagtagcagc agtcaggcct
     9541 ttaggtttgg aaagcatgag ttccgggtca ttaacagaga taagagcaag gctattcttg
     9601 tcaaccatta ccatcttaac cttgcgttct tcatcagtaa tcacatagtt aatagtgatt
     9661 tctgcagaag ttcctgccgt tgtattgata gccacaactg gcaagccttt tttagcagac
     9721 ttatgaagcc cttcataatc ctgtggtttt ccaccatttg tagccatgat agaaatacaa
     9781 ctagctgcat cctgtggaga acccccgcca agactgatga taaagtcaca gccatgttct
     9841 tgcaaagcag ctaccccatc tgtgacattt ttacaagtag ggtttggctc tacatcgcta
     9901 aagatgacat attcgattcc ttctgtatcc agtggtttta aaaccttagg taaaatgtca
     9961 ctgccttcga tgtacttatc tgtcaccaaa agtgcctttt tatagccaag ttccttgata
    10021 taaggaccca cttcatttac aacaccttta ccaataaggt tgactgccgg aacataaaat
    10081 gtagccatat aattttcctc ctgcgcctcc gcgctatcta tttaacatca ttatattagt
    10141 ttttgtattc gttttcaatt atttgtgaat tgtttaacaa atctttttaa aaggatagga
    10201 gggacataag ttcacctcct atatacacaa tttttattta tgtagcggtc ccaacaactg
    10261 acatgcacga tagtctgctg attctagatc ttctgttcca aataaggacc aatttttagg
    10321 tctaaagata tcttcctcgg gtacattatg catattgaca ggaattctca acatagaagc
    10381 caaggtaatc aagtctgctc caatgtgtcc atatgttatg gctccgtgat tagctcccca
    10441 attattcatg acgtcataga cagacttgaa agcacctttt cctgtcaaac gtggagcaaa
    10501 ccaagtagtt ggccatcctg gatctgtacg attatctaaa gtatggtgaa catcttcagg
    10561 aagttcaagt gtataacctt ctgcaatttg tagcactgga ccaacccctt ttagaagatt
    10621 gagacgtacc attgttactg gcatatcccc cttcgtcaag aaacgagttg agaatcctcc
    10681 tccacggaag tattcgcggt ttgctggtgg gaagtctgta ttttcaagca tagcctgcac
    10741 ttcactttct tccaactccc agaatggttt cataacaggt ttgccatctc gagtagcttg
    10801 ccctgtacca tccaatgtac aagaaccaga gttgattaga tgtaagaagc cagctgcagc
    10861 acaaccctct aaagtatgtc ccgttacacg tttaacagcc tctggactcc aataagtgcg
    10921 cacatcagca aagatttgtg gagtatttgt taatagataa ttaaagagca tagacacacc
    10981 atttagtgaa tcattctctg tcgcaaatac aaatggtttt cgaataccat tccagtcaaa
    11041 ctgagtattg aggaaagttt ccataaagtc cccatttggg aaatggtctg tccactgacg
    11101 ttgaccttgg aaaccagcta ctaaagcatg gtgaccaact gcttcttcct caaaaccaag
    11161 ttcagcaagt cttgggttac caaccattaa gtcacgtcca atcatgaaca tcttaataac
    11221 aaattcccat tgtctatctt tttcttcacg gcttaaaaca aggtcttcac ggttatggtc
    11281 gaatccttct tttacgtttt ctttcaccca tttgagcgca cgttcgaact cttcagggtc
    11341 gtaaatacca cggtccatac ggcgtgtgaa ctccgtcata tctaccgatt catttcgcat
    11401 tcctaggtat tcttggaaga aatccggatt tacaatagaa ccaccaatcc ccatcgaaac
    11461 actccccatt gataagtaag ctgtatctct catcaagcca gttgcaagag ctgcccgcgc
    11521 ataacgtaaa agtttttctt tgacatcttc tggaatagct gtatcattag cttcctgaac
    11581 atctctacca taaatcccaa aggctggaat ccctttttga gcatgtgaag ctagtacagc
    11641 tgcaagatag acagctcctg ggcgttctgt cccattaaat ccccaaatag catgaggaat
    11701 atctggagac atatccatag tttcactacc ataacaccag catggtgtaa ctgtaattgt
    11761 tgcgcaaaca tttgattttt taaacaactc atgggaagct gcagcctctg gaacacgacc
    11821 aatggtagat ggagaaatca cacattccac aggttcccca tctggatatt tcaatgtgct
    11881 tgaaatcaaa tctgccacac ttttagccat gttcattgtt tgtacttcaa gtgattcgcg
    11941 tacaccttga cgacgaccat caatagtcgg acgaatccca atacgtggat gttgaatcat
    12001 actattttcc tcttattttt ctgtttcttt catactaccg atgataattt ttaaaattac
    12061 ttataagtat aaacctctac ctctgccaaa cttaaaggaa ttcctgcgtt tctcaaagaa
    12121 attctaacct tttttccctt cagccctttt aagtctatgg atagattatt gctttctaaa
    12181 ctgtcaatat gttgtttaaa aacttcatga ttatttgaat catatataat aatatcaaaa
    12241 tttgataatc tctgaatttc agcatctgtt ctattataaa taattaactt ttctaattct
    12301 tcggtttgtg ctaaatctat ctcccaccat gaaggagaat ctcctttggt atgagtcact
    12361 gaatgatgac cataatctcc gtttttattt ccatcaactg ctagacgaga aaaaccattg
    12421 taatccgttg aactctgtcg agtttctttg gttaatgcaa tattagaaag tttcttcgga
    12481 gttctctttg aaccatagac ttcaacttcc gctaaactta acggaatagc tgctgatttt
    12541 aattctattt tgactagctt agcccctaca gaaggtactt ttaaagataa caaaccatca
    12601 actactttat caaaatgtct tctaaaaact tcttctcctg atgaagatag aaaaataaca
    12661 tcaaaattag ataaacgctg aggttcggca tctgttctat tataaatatc aactttagaa
    12721 accgtaaact cttctcccag atcgacctgc caccaagcgt tagaatctgc cttagtatga
    12781 gtcaccgaat gatgtccgta atctccatct ttattaccat caactgctaa agcagctaca
    12841 ccctcataat tggttgaact ttgagtagct accttatttg tagagactac tttatcttct
    12901 gttattttat ctatatcctc ttcagattgc ttaccatctg attctctaaa aacctctact
    12961 tctgctaaac tcaaaggcac tccactcgtt agtaatttaa ctttaatata ccttgctcct
    13021 ttttctttga aatctagact aacagattca cccgacaaat tattaacatg tttcttagca
    13081 acttcgtttc tattattgtc atatagaatc acatcaaaat tagatagacg ttgagtctca
    13141 gcatctgtgc gattataaat tttaacaagc ccaactttat ccattttttt caaatcgact
    13201 tcccaccaag agggattatc tgccctagtg tgtgttaccg aaccagagtt aaaattacca
    13261 tttctgttac catccacagc tctattaggg tctccattgt aatctacaga actttgtgtt
    13321 gttggttttg catatgctat attcaaatta ccatcattaa atttatctgg tgttgggaaa
    13381 gagactggac ctgtcccctc agtatttata gacatctcta ccattccatt atgattaacc
    13441 gtaatggtat aaacatgggt attctcatcc caattttctg tataagtata atgattttta
    13501 tcgccactta tatttatctg aggtttatga ccagtatgcc cttttaatgt aagtgttgtt
    13561 gtcctaaagt cattatctac aggattgatg gaataatttt tgcttatcca gttcgctaac
    13621 tctaattctt ctttcttcca actttttgat gcatcaaaat ttcctgataa tgcccacata
    13681 gctgtcttat ctgtcctgta attattcaat aaaatatgta aattatttgg attttcttta
    13741 acaacagcgt aagtatgtgg cgtcaaatct aacgataacg actttgtatt attagtatac
    13801 ataggcaaca ttacttgctg atttttattg atattagcat tactattata aatataccag
    13861 gaattaccta cacgctgagc atacccatct ccttcataaa gttttggata aagcgagttt
    13921 aaatagttga ctttactaga caattcctca ctatttttag tcaaaatttt tgcattaggg
    13981 aatatagatg aaatcttttc cttatcaatt ttctcatgta ttacaggaag aatatgatat
    14041 ctcccattat tatataaagg cattgtttca tcattcgaat aaagtccttg ataaaatccg
    14101 tttaatgaac taatcctacc ttctccattc caaaatacag cttttgttct atttacaact
    14161 tcttccttac ttggagctgg attttgtata gcatgtctaa agaaaggaat aataccttta
    14221 gtaaatgctg gagttggtac atcatttgtc ataaatgtat acgcggcaca ttcgaaatta
    14281 taaactgtgc ctcccccagt atatacattc atcatttcca tagcaatcat tgattctggt
    14341 tccgatgcat aggatctcat atccctagct cttccagttt caaatgtgtt tgtataatgt
    14401 ttttcccacc atttccatgt atctgttgat gagccccagt tatcacataa gccactcaac
    14461 caaaatccac taacgataga atctgtaccc gcatcatctc ttattggcgt atttttagtt
    14521 gccaacacca aatttttatg atatttttga ctcgcttcaa agaatgtcgg atcattcata
    14581 atagtttccc agaaccattt ttcatgatca tgccagataa aatgcgctcc atatttggca
    14641 caaacttcca aatatttagc actatgcgga gctaactggt tattgtaaat ccaataattc
    14701 tcaatattta aaacaccttt taacacacta tacttttgga attgttcatc taaccactct
    14761 ggaggaactg tattacgctc tccagccgac ataataacca agaaaactgg aatgtttaga
    14821 ctttgagctt cctccaacat cttgacatac cattctctca attctttcgt atctcgtgga
    14881 atacaacttg ttggtttaca gacttttgca ggatgaagtt caatcgctgc atatggtttt
    14941 acatcttcag aaatagcttc ccatgctccc ttcaatgtgt tcccccacca taatccgtta
    15001 ccattatcat tgccatacaa cggagaaagc aacaatggcg attcattatt aatcgtcgtt
    15061 ctcatttgaa cacgattatc agccttaact cctgctaaca atccaaaaca taacatccca
    15121 atacatacaa acagtattgt gattaatttt ctttttattt tttctttatt catgacttat
    15181 acctaaaaat ttaactcaat aattttttct gaattaaata ccaattcaat attttgtaca
    15241 tcagtatttt tgccatatac tcttactctt actttttgat ctttgtttcc tccttccaat
    15301 tttaggaatg ttatatcccc atttttccaa gcaaacgata ccttatatcc tcctcttact
    15361 ctgaaacctt tcacttctcc ttctgaccaa gcagaaggta aagctggaat tagtgataac
    15421 caattatgat ggctctgtac taataattca caaattccac tcaccaaacc taaattacca
    15481 tcaatttgaa atggtggatg gtcaagaaat aaattgccaa gagtcgcatt atttaacaaa
    15541 ccattaatct ggttataagc aggttcacct tgatatagtc tcgcaaaaaa atgaatcagc
    15601 catgcagcac tccaacctgt ttgtgtacta gcatgcaaac cacttactaa ccaattatta
    15661 atcgcttgct ccctatcctg tgaagataaa aagttagcgt ttgataatct tctattgata
    15721 gtgattttag ctgcttctgc taattccgga gttttatgaa tatcaatctc attataagga
    15781 taaagcccaa atagaggtga aatgtgtcta tgaccaggct ctacttcttc ataatcctct
    15841 agccattctt gtatttgccc attactacct atttttgttc taggtaattt cttttttaac
    15901 tccttcacac gactaataaa atccgaattg tctcctaatt gttttgcaat tccaatgcat
    15961 gaatcacaaa aatatcttaa aatttgatta tcaattgtag atgatagaca agcatttcct
    16021 tcaataccat tttttaagcg atatttattt tccggtgaga cacttggacc tgtcatcaag
    16081 tagccatcca cctcaaataa ataatcttca aagaaaagaa atgcttcttt tatcatttca
    16141 aaatgttccg taagaatacg ctcatcttgg aaatataaat agtgttccca aatatgagta
    16201 cataaccatg gaatagttaa tacccaaatt gcagccccca tggcatgaga ttggggagcc
    16261 gtatcgccaa aaccatccgt attatgatgt gctgtaaaac ctctagctcc atacattttc
    16321 ttagcggtta gtcttcccgg ttctctcatt ctttcgagca tatcaaataa tggatattct
    16381 acttctggta aatcacatgg acctaccatc caataattca tttgagtatt aatattaatc
    16441 gtatatttag aaccccaaat tggatttaat tcatcacacc atattccttg aagattggca
    16501 ggtaaaccat tcggttgact agacgatatt aacagatatc ttccataatg aaataacaag
    16561 ttagtcaagt agttactata ctttttagtg ttttcaagaa gtagattcgt tggaatgcta
    16621 agacaatctt tactatagtc tagtttaaaa tcaactctat taaattgctc ctgatatttt
    16681 tttacatgtt catctttttc tgtaaagtaa tcaatactac taaattctcc ctgaagagaa
    16741 gaaatatcta tatttcccca ataatccgtc attgatttga gataaagaaa tacctctgta
    16801 gcattccgaa taactattgt ctctcccaat acacttactt caccatccgt aaccttagaa
    16861 tgacatacta ctttaaactg aacacctttt ctacctccag cagaggccga cattaaaatt
    16921 gtacttgaat ccagtttaga tacttcatca ttaaaccgtt tatttctacc caaattaatg
    16981 tttaaattta atgtgttttg aactgatgac actatacggc aacataaaat attcttatta
    17041 aaactcgtaa aatattctct ttttatttgt aaattacaac tattaggctc aaacacaaca
    17101 ttagaaatag ctgtatctaa atctagctct ctttcataca atgaaagagc acaagactga
    17161 atatctatat gctcaatgta aagttcccca agtaattcat agtggctttg atctcttggg
    17221 gtagcaaaca ttgttaactt tatcaattct tcggctttct gaatttctcc atctaaaaga
    17281 tattcccgaa tttttttaag atgcaatagt gagtctggat tatttctatc tgactttcct
    17341 ctataccaaa tagtctcatc gtttagttga atacattctt ttgtagctga accataaatc
    17401 ataccaccta aatgaccgtt cccaatcggc aaggcttcat tccaatttga ggcagctttc
    17461 ttataccata atttcactct ttacctctct tccaaaatgg aggtgatatc ccaaatacca
    17521 cctccacact ttctactact tcaaaattcc taaaacaact aggataactc caatagccat
    17581 aacactaaag attagtacaa ccggattctt tccttttcta attaatttac acattaataa
    17641 agtcaaagcc atagggataa atcctggaat taattttgta atcatttctt gaacagaaat
    17701 aacaagttcc ccctgcttaa attctaatcc aaaattaata ccaaccattg atggaatcaa
    17761 accacccact agtactagcc ctaatgctgt cgccatactc gtaacgcgat tcaatgttcc
    17821 ttttgtatta ttttcttgga taagactaga acccttagta tacccatatt tcaaaccgaa
    17881 atatttaaca ggaatattaa taatattaaa caatattaag gcgataaaga tacctaaagc
    17941 accgccgtct ttagaataag acgcaccaat actaaaacag ataggaacta gtgtcagcca
    18001 gaacaaacta tctcctagac cagccagtgg ccccatcaag ccaactttaa taccagtaat
    18061 tgaagctgca ccttcatttc cttcttgttc ttccatagcg gaagtaactc caagaataaa
    18121 tggtgccgct gtttgatgag tattgaaaaa ctcaaggtga cgtttcattg caggagaagc
    18181 tgaatctttg tctgggtata gttttttcaa tactggaaga attgtatata gaaaacctag
    18241 gttctgcatt ctctcatagt tccatgaaga accatacata aaacttcgtt tgaaaacttt
    18301 tttaagttca actttagtta ctttattatt catcatagat caagatcctc ctcaacatca
    18361 ctacttgaag ttgtttcttg tggtttactt ccaatcatat cgtagaagta tgctaccgca
    18421 ataccaacta gtgagatccc aatggttgac attcctccat acacagaaca aatgaatcca
    18481 atcaacaaga atacccacat atttttcttg agcatcatat ttaaaagcat accaaaacca
    18541 attgaaggta gtaaagcacc tgcagagtta agtccctgca taacgattgg tggaaccttc
    18601 gcaaacaagt ctgccacata ttcccctcca agcataatag ctaggaaaat tggtacaatt
    18661 ttaaataacg tgattaaaac caaacttgaa taatgataaa aaccgatctt tgaataatct
    18721 ccgtttttag catcattatc agcttttttc acaaaataaa catctaaagt ttttgcaaga
    18781 acatccaact gttgggtagc aactgcaatt ggaactgcta tagcgatacc agcagtttct
    18841 ccttgaccag ataaaatacc aaatgcagta ccaataatcg cacctgaaat agtatctggt
    18901 ggagtgtaac ctccaatacc tgttacaccg agccaagtta attcaagagc tgaaccaata
    18961 agaacacctt gggtgaaatc tcctaagact aagccaacca ttgcacttgt aactaacgga
    19021 cggtgaatca taaataacgg tccattatag tcaatagtgg caataatccc aactaatgtc
    19081 accagtaatg cttgtgtgaa tagcatatac tgtacctcct taaattattt ttataaaaat
    19141 ttttccaaca ttgtaacttt atcattagga accatttgaa tttcaactct cgttccctta
    19201 tcaactattt tcttaaaata atatttgtct tcttcaccta gagctacacc tcccgttacc
    19261 ttttcatttt cctccgtttt actcatctgt cctacattga ggtactccaa ttttaaattt
    19321 ccttcaatag aatcatacac atcttttgga tttgtatata tcagcattgt tctctttttt
    19381 attggcacag agtttaaaac ttccacaaac cgttttacac taaagaaaac aatttttaaa
    19441 cctactggtg cagaaatctt taaaatagat tgtcgtgttt tatcttctga gatgcgatca
    19501 ttaacaatga taacttgctc aatatcatac ttttttagcc acgtagtgac aacttgacca
    19561 tgtaccagac ggtcatcaat acgaacaaac tctatagaca taaatcttct tcctcctcta
    19621 cgttaagttg ttgtttaaca ttaaacaaac tattttgagc attgtgaaca atttcttcta
    19681 aattgatttt tgaatcataa tttgatatta attccactag gagagggata ttaaaccctg
    19741 ttacaatatc aactgaatcc aaatttaaaa accgtgacaa agcaacatta ttaggacttc
    19801 ctccaatcaa gtcagtcaaa acgataacct cttgatttga gtctaacagt tcatttactt
    19861 gatttttaaa ataatgttca aactctacaa tattctctcc aggcatcaaa cctaatgtcc
    19921 taactctatc atttgttgtc tcaccaacaa acatttctgc ggtcatgaga gctccgctag
    19981 caaaattacc atgactggca actaaaattc ctctattaaa cattttctct ttcaacaact
    20041 actcctttct taaggataat attagcataa agtgaagttt ctcctgtagc aacaatagca
    20101 taagctttct tactacgttc ataaaagtct tctcttctaa gataagtaat cgttttaaga
    20161 tctgtaccat gaccttcaat catctgtcta taggtacccc atatcttagg aatatcatca
    20221 cccgaaacaa cgttcataaa ctgaattgaa ctatcgacgt aactatctaa tggcattaaa
    20281 tacagaatgg aatctaataa ttctggaata tttacaccat cacaacgaat tagcttattt
    20341 gcacatgagg cagaaggata attcgcgtca gctaatacta tttcatctcc atgtcccatt
    20401 tccattaaag tcttcaataa atctggagaa atatttttcg gtatatgttt taacattaat
    20461 atcctcccta ttttctctga ccgtatgttt taaatttttc tgccattaaa tccatctcct
    20521 catcaggaag aactactggc tctccaaaat tcttagctaa acaataaatt tttgcacaat
    20581 attcaacttc ttcaacaata ttaaatgcat tcaataaatt ttgtgcacct gctaaaattc
    20641 catgattcgc tagtaaaact gctctacgac cttccattgc tttagctgca ttcacagcca
    20701 attctttcgt accatatgtt gcatactcag ctacccgaac atctttccct gccactgcaa
    20761 tcatataatg actagccgga agtggttctc tgagacaagc taatactgtt gcataagttg
    20821 tatgagcatg gataattgca tcgatatcat cacgagtttg atattgaatc aaatgcatat
    20881 accattcgct agatggcaag cgttctccct ctacaacatt tccattaata tccatcacta
    20941 caatatcgga ttctttgatt tcaaagaaat caatacccga cggggtaatt gccatcaatt
    21001 gtttttcacg atcgaaaaca ctgagattcc cacctgttcc tttcgtcaaa tctgtttcta
    21061 ctagcttctt gccatactta attaattctt gttttacatc tgacattctt gtcctcctca
    21121 tatcaaaaca ctaaatattt ttcaattcac caattatccc cccttcttgt acaaaactta
    21181 agaaggggga gggaggcaaa tttacaaact ctcaatcttt ttaattcttt tgggagtaat
    21241 aactctctaa ttgtagaaac tcctcaataa catggtgagc ttcttccatc ccttttaatt
    21301 gtcccatagc tatgagctgc acaacaatat tccccacagc tgtaccctca gtcgaacctg
    21361 taagaacctc tttaccagtt ctatcagcaa tcatttggtt aaaataactg gctctagcac
    21421 ctcctccaat cacatatatc ctcttataaa ccttatgagt tagttcttct agtaactcta
    21481 tcgctttcct atacgtttca gctaggcttt cataaacaat cttaaatagt tgtccatctg
    21541 tccactctct agtttcatga tgataagcta gatattctgt caaagtcttg tgcatatcag
    21601 attctgttgc aaattcagtt gattcagtat caatcagagg aagattttct ttttctttct
    21661 ccaccattgt cctaatatca tcaaaagaat aggctttccc tcttcgttca aatgaacgtc
    21721 ttagttcctc tatgatccac aaccctgtac aattcttcag aaatgtaatc actccatctt
    21781 taccgacttc atttgtaaat ccataactga aggattcggt agtaagaatc ggtgaagtaa
    21841 gttccactcc aaccaaagac caagtacctg atgaaataaa taaactacct tctgtcttag
    21901 gtactgagac aatcgcgctt gctgtatcat gactacaaac attcacaaca ggaatatcgc
    21961 ctaaaccata ctcctttttt atccttccaa gaacatttcc ctctgaaaca atttcaggaa
    22021 gtaaagatga attcaattca aatagtttta agatattctg attccaattt tgactcctag
    22081 gatcaaataa ttgagttgtt gaagcaatgc ttttttctgt agcaaactta cctgtcaaga
    22141 gataattaaa caaatctggc attaaaagaa tcttattggt cttatagaaa gagtcaggag
    22201 attcttgacg tgccttaaag agttgaaaca aggtatttat ctccataatc tgatttcctg
    22261 tctctgaata cagtttttct aattcagtca tttcagatat ttcctttaac actccctttg
    22321 ttctttcatc acgataatga acaggttgtg ataacagctt accttcatta tcaatcaggc
    22381 caaaatcaac tccccatgtg tcaataccga tagataaaat cttgtaacta gtattagcca
    22441 agcggatact ttcaagaatt ttagctagta gaaagtcaac atcccaagat aaatgccctt
    22501 ttactctaat aggtagatta gaaaagcgat ttatttcttc cattactagt ttattttcag
    22561 aaaggtaacc aacgattgct cttccagaag tcgcacctaa atctattgct aaaaccgctt
    22621 ccatttttct tctctcttcg tccttgatta agtttattat aatccccaca ttttattttt
    22681 tcaatatgtg aacgcttact tggataatgt tcaaatgtta acccaatatt cataaaaata
    22741 attcaaattc ctccaatttg tgctataata tagttgaaat gataaattag gaggagctta
    22801 tgataaaaga tgaacgtgta cttgaattga ttgaaattat caaaaagaaa aaaagaattg
    22861 ccgtaaaaga gctggcagaa atcactttct ccagcacaag taccttacgt cgtgatttaa
    22921 ttttcttaga aaatcaaggt cttatcaaaa gaaagcacgg atacgtgacc ctgtcctcta
    22981 tgaacacaat tgaactttct catcaaatac gtgaaggaga aagtactagg caaaaaagac
    23041 taatcgctag tctcgctaaa gactttattc ggtctggtat gtgtatctat ctggattcca
    23101 gtactactgt ctacgaactc tgtccctatc tttctgaact tgataatttg attattttta
    23161 caaatggttt acatactgca caaaccctat ctgaaactgt taaagatagc tccaaaatct
    23221 ttatcacatc tggcgaggtc aaacatcaat cctgttccgt ggtcaactat gataaggaaa
    23281 attctttatt agatcatttt aatatcgatt tagcattttg ttcagcaaga ggtattgatg
    23341 accaatatgt ttatgaagct tctctcagcc aagctatttc aaaaaagaat attattgaca
    23401 aagcccatga aaccatctta ctgattgata gttctaaatt ttacaagact ggatttttta
    23461 aaattaatcc cctctccaaa tacacaacct ttatttcaga caccgtgcca gatcaaaaat
    23521 tattagacgc agtcgaatta tttgatggag aatgggtttc tgatattcaa tgaaaatcaa
    23581 ataggaagct agtctcagct tgctcaaagt acagatttga aaactgatga agtcagctcg
    23641 aaacactgtt ttgaggttgt agatagaact gatgaagtca gtcacatata tacggaaaga
    23701 cgaagctgac atgatgtgaa gagattttcg aagagtattc gttctgtctg ctgactgatt
    23761 tacaaatatt caccacatga cattattttc ttagcaaccc caaaaacaga ggctggacaa
    23821 aaactcaatt tcaggagaaa atggagtaaa ccttcccaca ataaaacgca tagtatcaag
    23881 tttttgcaca cctgatatta tgcgtttttc tgattttaaa gactttgtcg cctagaccct
    23941 atatttcaag aattaagtga ccttgatgat ctaaatttat tgtggtatac tatttttgtc
    24001 atcggttacc gattacgttc ctatgggttc gtgagaggag gtgaaactaa tgagccttat
    24061 catagagctc gctcttacta ttatagcgga tgttatagct ggaattatct tgtatttcgt
    24121 ctgcagatgg ctagatagta aggagtagac cgactgacta gcctataaac acccgttaaa
    24181 tcgctaagat acgtcaaaaa agcccttaac tacggccata gttaggggct ttggtgttct
    24241 aatgaacctt atcaattaac tacattttag catataatct acaatagttc aagcattaag
    24301 tgaggttgat gatctaaatt tagtgtggta tactattttt gtcatcggtt accgattacg
    24361 ttcctatggg ttcgtgagag gaggtgaaac taatgagcct tataccagag cttgctctta
    24421 ctattatagc agatgttata gctggaatta tcttgtattt cgtctgcaaa tggctagatg
    24481 gtaagaagta gaccgactga ctagcctata aacacccatt aaatcgctaa gatacgtcaa
    24541 aaaagccctt aactatggca ctagttaggg gctttggtgt tctaatgaac cttatacact
    24601 aactacattc tagcatataa gcccagatat ttcaagagtt ttatttattt tttcaggttc
    24661 ccttagttct gaaaggtcta taatgaagtt agccatctag tatcaaaaaa ccgactagct
    24721 cttatgaact agtcgatttc tcatcaatgc gccaacattt cttgggcgat ttcttggcca
    24781 gataggttat ctgggtagta ggttggccag ttgtccattt cttcaaagag ggcttcttgg
    24841 cttgtgcctc caaagaagat atggaaatgt tctgccttaa ctggggcaac attgtggtca
    24901 ctaaactgaa catacttgaa ttgtccagcg tcagcatctg tggcttcaaa gaggaaacgc
    24961 acgccacgat tgcctttctt gtaagtcaaa attttcttac cgacatactt gtaagtgtat
    25021 ttcttgcttt gtccaccttg aacaaattcc atagtattat cagtaatgtt aatcttagtc
    25081 acatctgtct gatagccttt tgtatagtaa gccttgtact cagcctgggt catcttacca
    25141 gttaacttag ccttgtagtc aaagacttgg tcaaacgtgc cgtcttcaag gaaaggataa
    25201 actgattgcc agttacctgc atagtcactc aaggtacggt ccttgacagc tgcatcctcg
    25261 aagtaaccat tttggactgt cttggtatcc tctgcctttt caggttcgat tgctgggcct
    25321 tcttggtctg ttgtttgttt caaagccttg aggtttttct ccatcacgga aatgtagttt
    25381 tctccagcct tggtgtcctc ttctgtcaga ctttctaaag gattgaggac atcagttttg
    25441 acacctgctt cttttgaaag tgtgttagca agggcttgtg aggcattttc ttcaaaatag
    25501 atataggcga ttttattttt cttgacatac tctgtcaatt ctgccaagcg agcagctgat
    25561 ggctctgcat ctggagaaag tcctgagatt gcgacttgtt tgagtccata gtccaaggca
    25621 agatagttaa aggctgcgtg ttgagtcaca aagctctttt gttttgcttg agacaagcct
    25681 tctgcgtaag ccttatccaa ggcttgcaat ttttcgatat aggcagctgc attcttctca
    25741 aaggtctctt ttttatcagg ataatctgct gacaagctgt cgcggatgtg ctctactagt
    25801 ttaatggcac gaactggtga taaccaaaca tgggggtcaa actcatggtg atgaccttct
    25861 tctccatggt catgatctcc ctcttcttcc tcgccacctg gcaagagcaa catatcgcct
    25921 gtcgccttga tggttttcac ttttttctta tccaaggtat ctagcaattt aggtacccat
    25981 gtttccatgt tttcattttc ataaacaaag gtatctgcat cttggatttt ggcaactgcc
    26041 ttggcagatg gttcgtattc atgaggttct gtcccagcac cgattaggag ttctacatta
    26101 gccgtatctc ctgcgacttg cttggtaaat tcatagacag ggtaaaaggt tgtcacgata
    26161 ttgagtttac catctgcctg tttttgattg gaacaagcca ctaaaaacaa ggcacataga
    26221 ctggctagta ataagctaat ttttttcacg ttcgtctcct atttgataaa acgtcttact
    26281 aaactgatta gtataaagac agttacaaaa ataatggtaa tacttgcact tgcaggtgtt
    26341 tctgcatagt aggaaatgta aagtcctgct accattccca aaaagccaat cgcactggca
    26401 agcagcataa ccgatttaaa gtttttcccc agacgcaggg caatactagc tggcaagacc
    26461 ataatggtcg ataccagaag agctcctgct gcaggaatca taagggcaat agccacccct
    26521 gtcaccatgt taaaaagaat ggacatggta cgaactggca agccatccac aaaggccgta
    26581 tcttcgtcaa aagttaagat atacatagga cgaagaaaga gaaaggtcaa aatcaaaaca
    26641 accgccgcaa tgacaaagag ggaaatgacc tgttcttcac tgatagtcac gatcgaacca
    26701 aagagatatt ggtccaaact cattgaactc gagcttttac ccttgctcat gacaatcaga
    26761 gaaacagcca gacctgttga catgaggata gctgtcccga tttccataaa gctcttgtaa
    26821 accgtacgga gatactccag aaagaccgcc gcaatcaaga caatggcaat agtagaaaca
    26881 gttggagaaa tccccaaaac cagaccaaag gctacacctg aaagtgagac gtggctaagg
    26941 gtatcactca tcaaactctg acgacgcaag atgaggaagg ttcccaatac cggtgagaaa
    27001 agactcatag caataaccgc caaaaaggcg cgttgtataa agtcgtaaga taataaacta
    27061 agcatggccc acctcctggc cattctcatg aacgttgaaa caacgccatg gcgagtcttg
    27121 gttacggact agatgaatat tgcgatccgc ataatcctta acttcttcag ggtcatgggt
    27181 aatcatcaaa acagccttgc catgatgatg ggcgctgtgg tgcatgagtt cgtaaaattc
    27241 atttttactt cctgcatcca tccccgttgt cggctcgtct aggataaaca catcagggtc
    27301 agaagcaaac atacgcgcaa ttaccgctcg ctgcttttgt cccccagata gagaccccaa
    27361 gcgtttgtct cgatgttccc acatgccaac tgagtccaga ctggccttga tatgctcctc
    27421 atcatgagca ttcaaacgac ggaaccagcc ttttctcgga tagcgacccg acttgacaaa
    27481 ttcatagacc gtacttggaa aaccagcatt aaaactggca atttgttgag gaagataggc
    27541 tattctcaat ttcttacctt gcgtatttgt ctttgaaata gccacctttc caatgcgtgg
    27601 ttgcagaatt ccaagactag ccttgatgag cgtcgtctta gccgctccat tttccccagt
    27661 caaggtaaca aattccccac tatcaacaca ataattgata tgttcaagaa caggctcctt
    27721 atcataatag aaggacaaat cctctaccgt aatatatctc attatttgat ttctcctact
    27781 aaagcagtca aaaaccgctg aatcactttt tgttcatttg gagtaaactg agtcgccact
    27841 tgttcatagg ttaaaagtgt atgctcatgg tgatggtggt gctcctcagc gattggacga
    27901 gccaagtcag tcaactgata aaaaatcaca cgcgcatctt tagaatcttt agatgtttcc
    27961 aacatccctt ccttgaccaa agacttaatg gccttggtaa ctgccgcctg actgacattg
    28021 agacgacggg ccaattctga atttgttaaa gattcctctg acaagagcat aaggatatgc
    28081 tcctgagtat tggtcagggc cacctcgcta gtgcaatgac ctattaggat ttcatgctga
    28141 ttttccgcct gcaaaatcac ctcattcaaa aaagcattga tatcctttgc tagctgtctc
    28201 atatctgact cctttccttt tagacttctc ttttttaaga gaaaaatact attctttgac
    28261 attttgttta ccagttaatt atatcacaag caaaaaaaga gtcaagaaaa aacgtgaaaa
    28321 ctagtttcat tcttgaactc ttctatatta tattatctat tgaaattctt tgacatctcc
    28381 atcataagtc gcccaatctt tgctgaaaaa gcgctcattc agatggtaag tcggagctgg
    28441 tgtgggattg gataggaaag gatcaactgc cttgtcaaaa gccaaccaac ccaaccaacc
    28501 aaggtgaatg gtgtccttca taaagaaagg ctccccgccg tccttagaaa aatctgctat
    28561 attggtaaaa ccttgacttt ctaactggta gcgaatcttc tgcaccgttt gttggtacat
    28621 atcctctcgt agaccagcat agtccatcca ttttttatta acaggtggaa tgataaaaat
    28681 cgggtttacc ttagatttag aaaactgtgt taaaaccaac tgcaagtcat tatactctgg
    28741 cgacttgaga taggtaaagc ttttctgaga atcctttaat ttcttcaaat ccttcttgat
    28801 ctgctcatta tagaaataat tttccattcc catctcatta ttggaagtat ttttttcagc
    28861 atctgctttg acaacatctt ctattgcttg ataagaaaac tggtctggca agatttttaa
    28921 atacttagct acatgcttat cgtagttaac atagcctcta accgaaaact gaccaaaaaa
    28981 ggaggcttgg cgttcattaa aacgagccaa taattcaatc atttcattgt ctgctgtcga
    29041 caattctcct ttacttgcca acttctgaac caggtccttc atagctacgt ttgggaactg
    29101 ttgcagtaag cgagtcgctg catattgact agcctgatcc ccagattgat gtttcagaaa
    29161 actagtcaac tggtctccat taaaatactg ctggaaggct gctggatcat agccattttt
    29221 actgaaccac tgaggtgaga taacatacac aacttgttta ttctccagct gtggtaacat
    29281 ctgttgcatt ccaaaatatt ggttaagcga tgcagctccc ccctgtccta aaagataagg
    29341 acggtaggaa cgattgtatt tctcagctaa taccgcagga tgagcaccgt caaaacgaag
    29401 ccattcacta gagccaaaga agggaacaaa acgcacattt ggatcagata gtgctctgac
    29461 tttttgactt cgctccttaa aactatcgat agtagtagcc actgctgaac gcttttcagc
    29521 tcctagatta tgatgcatct cagtaggata aaagaaaatg agcagaaaaa ccaacaaacc
    29581 agcgatcaag accggtccga agatcatcca taagcgttta agcattttgt agctccacaa
    29641 taccagctat gattttatta gctgtattcc agtcgtcacg accaaactct gttacaggga
    29701 cacgaatgtc aaaacggttc tcaatctcca caatcaactc aaccgttccc atactatcca
    29761 agacacctgc atcaaaaaga tcttcatcca tcatgtcaga aacatcttcc ataaacaact
    29821 catcaataat ttcaataact tctgatttga tatccatatt ttatttcctt ttatttttta
    29881 aaccatagat tattcaagaa tccagaaaag attaagaatg acaacatgac aacatggaaa
    29941 gtgacaacca tgccaagcaa ctgaatccag cgattctcag gtagggcagc cttccctgct
    30001 tttttccgtt ccttattgag cgtttttttc ttgcgaaccc aggcatcatt gatgaccaag
    30061 cctagtccat gaaagagtcc ataggcgata tagtaccagg tcacaccatg ccaaaatccc
    30121 ataatcagca tatttacaat gtaagccatg cttgaggtta cattacgatt tttaaagact
    30181 ttctttctgg ttaacaccat caccattcgc ataaagacaa agtcacggaa ccagaaggac
    30241 agactcatat gccagcgatt ccaaaactcc tttaaatccc ttgataaaaa gggcttgtta
    30301 aagttgatag ggctacggat tcccatcaag tttgagatgg ccaaagcaaa catagaataa
    30361 cctgcaaagt caaagaagag ctccagacca aaagtataca taactgccaa ggcatagaga
    30421 ttaaagaagc cacctgactg caaggctaaa ttcttcagag gaggtagtaa ggtctctcct
    30481 aaaacatgag ctaggataaa cttatacaaa aagccccaca tgatatagcg gacagattca
    30541 tccagcatat ccatcaactc atctcgctca ggaatggtct gataattttc attaaatcgc
    30601 ttaaagcgat cgattggacc actcgagaaa gttggcatga agagaaggaa acggaggaat
    30661 tcccagaggg taaaatcctt aatcactcca tctctcagct cgatgataat cccaaccgaa
    30721 cgaaaggtca ggtaagaaat tcccaagaac ccaagcaaag actgcgttcc attgatagct
    30781 ggttgcacct tgacaaagat aatcggaagt agggacagaa aactaactaa gtagaagacc
    30841 cacttgccat ccttgctttt tcgataatgc ttgtagaaaa gcaggagcaa tatttcccag
    30901 caaaggtaaa tacccaaggc agctagttga ttggtctttc cacccaccaa catggtgaca
    30961 ataaagaaga gacttaccaa cacttcatac caggcaaagc gtttcttgaa aaagaggcct
    31021 ataaagatgg gcaaggttgc agcaatcaca taaacaaaat actgaggatt gccatatggc
    31081 tctaaatgag gaagctgttg aaaaaactcc atcatctctt attcacctcg ttaatcaatc
    31141 ctttgatgtc aatctttcca tttggagtta gtggcaaact gtctcggtaa aggaatttag
    31201 atggcatcat gtaggacatc atgatgtctg tcaggtcttc cttgatggcc ttggtaatat
    31261 cgatatctcg ctcaaactgc tcacgaacac cgtcttttaa gatgacataa gccaatagat
    31321 tttgtacctt atggtccttg ttatagcgcg gtactgcgac agcagattcg ataaagcgag
    31381 acttgttgag gttttgagag acatcttcta actcaatgcg gtaaccgtta aacttaatct
    31441 ggaagtccat gcgtccgccg taaagaagca agccctcatc tgtcatggtt cccacatcgc
    31501 ctgtgtgata ggctggcaga ccttcaaact caaagaaggc ttctgctgtt ttttcaggat
    31561 tgttcatata accttttgaa acagctggcc cagaaacaat gatttctccc tgttcgccat
    31621 ttggcagttt atttccttcc tcgtcaatga taaaggttgg agaatcagcc ttggtatagc
    31681 cgattggtag gcgtttgaga gtcgctaaca tctcgtctgt cacggcaact gctgacagag
    31741 ctactgtcgc ttctgttggg ccgtaagcat tgatgatacg ggcatttggg aaacgctcgc
    31801 gcagtttttg agctgttttg accgtcaatt cttcaccatc aaagtagaaa tgcgtgattc
    31861 caggcatttt ctcactgttg aagtattcag acaacatggc catatctgca aaggatggtg
    31921 ttgatgtcca gatagcgatt ggcaatgaaa agatagccgc aaagagttgc ttaaagtcct
    31981 gagtgatgac tgaaggaaga gtgaaaagcg taccaccaag tgccaaggtc ggtgcccaat
    32041 acatgacaga caagtcaaaa gaataaggtg gctgtgccag catttgcgga cgactcggtg
    32101 tcgcaaattc cttatccgta atcatccagt ttgtaaagct gaggagatta tcatgtgaaa
    32161 tctgcactcc cttaggctta ccagtcgtac cagaagtaaa gataatgtag taattatcat
    32221 ctcccttgac tggatgcgtg atttcatagt tgttcccttg ggcaaaggct tcttgaacct
    32281 gagctagatt tatcattggt gtagaaacct gctccaaggg aaaggctgaa atggcaataa
    32341 tcaagcttgg ctctgctact tctaaaatag ctgaaactcg ctccaaggcc gaatggctat
    32401 caattggaat gtaggcatga cctgacttag tcagcgctac aaaggttgcc aacatttcat
    32461 attcttggcc accaaaaaca accacaggag acttctcagg caagcctagt tggtcaatga
    32521 ctgcagccaa actatccgaa tcagccttta aatcgccata agtgtgttcc tgccccaaaa
    32581 cattatagac aggatagcta ggctgtgtct gagcaaaatg ctcaatggtt tcaatcatat
    32641 ctgctattgg tttatttgac acaataggga ttctccttca agttaaaatt cattatagat
    32701 aaagcttcct tgaccctgac caagatagct aaagaagtaa agcagcccta gaaagataag
    32761 aaaatacaag gctgtccgac caagaaagag gtacaattct tttctctgtt tcatcaagaa
    32821 aaaccattca tttctgtaat ttttcgctaa aataagagtg attcttacta gcttattttt
    32881 ctaccattgt accactttat atagtatctt ttcaattgtt taccgtatgt ttccaataga
    32941 tttcagctta ttttaaggat tatacagttt ttctatgtat attttcaaat agagtgatcc
    33001 tgcttcaaaa ctccatttca ggagacaatg aagtaaatct tcccataata aaacacacaa
    33061 tatcaagttt tttcaacacc tgatactatg cgcttttctg atttttaaag actttttaac
    33121 cactctctca tttaaaataa tctcgtctga tataaattaa aatagcttct atcatcagac
    33181 aaatggctga tagccaaaaa ctgatgctaa taccaaaact ctcagtaata tagctcatta
    33241 gcaaaacaaa tactgaaaat gctaatgtag aaatcacttc aagaacggaa tagacattaa
    33301 ctaaatgatt ttcctctact gtttcctgaa gaaatacact ttcaggaact tcttttagtt
    33361 gcgataacat accaactaaa gctgaaaata ataaaaacat ctgtgcgttt ggaaaatata
    33421 gaatagtcag tgtcactatt gccatagcta caagaggaaa aagaatactt tcccatttag
    33481 cagcaaggaa cttttcagat agcctaaaag caattaagcc actaattata ataccaatag
    33541 agtatgctgt attagaatat ccccagtaac tttccgtttt atttaataac tccgttacaa
    33601 aaacaagtat aatggaagaa acccaaatcg tatttgaaaa aatttccaat aaatttgctg
    33661 atacaaaaag tcttaatcta ggatttctag caactaactt ccaacctttg agcaaaattt
    33721 caagattagt ttctgactct aacacctcca cttcagcgtt aggaagaaat aacatcagaa
    33781 agctagaaat gatatacaag actaaattga tacacgtggt aggtaacaga ccaattgttg
    33841 caaacaagag tccacctaat ccccaaccta tcaattgaac agcttcacca gtcattgata
    33901 aggctgaatt agccttaccc aaatcggtcg catagcgtgg cacaatagca taggaaacgg
    33961 gtgctgcaaa accatctagt atggaaattg caacaacaaa tagataggtc accaaaggcg
    34021 ctacggattg cattacggta aacattccta ccagtatcgc caataatata gtctttccaa
    34081 attgagataa agataaaacc ctatttagcg ctaacctttt agtaaccaac ggaactaaaa
    34141 gactcgcaac aaaagaggat attcctatta agataggaac tagtgatgtg gcaattactg
    34201 attttgaaat aatgtatatg ttagcaatga ttgttactct aaagaaaata tctgctaaat
    34261 ttgcaaataa ttgagagact aacaacttga caaatgaatt agacatgtag cgctccccct
    34321 ttagttacaa actttggaat taaatttgat ttttaatatt ttagcataaa atagcagaaa
    34381 acaaaagtga ggttttttac atgaaaaaac aaaaactatt gcctttatta ttcctaattt
    34441 taggaggaat tatgattatc gttgttggct agtactaaga agttagttag tagaataatt
    34501 acatcttcaa tcgaaaaaga gactggaaaa agtcttaaaa atcagaaaaa cgctcaaatc
    34561 ctttggcgct ctaagctttt ctaatgatag atttagatag tcaaaaaaat atctgaaaag
    34621 ttcccaggat cgtcgtctca gcatcaaaaa tacgtgaaat ttgcataatt aaaataaatt
    34681 tcaggggagt taatcgagta ggggataatc tctagcccct ctcacaccac cgtacgtgcc
    34741 gttcggcata cagcggttca actaactttt aacgcatgtc gttcaaggta ataatccaaa
    34801 cacgaaacca gtccacgttt ttccaggact ggttttgata tagcacgttt aagtaccgac
    34861 ttctgagcta ctaattgata atggtcgccc cagccagata ccttatctgc tatccattta
    34921 ggaactccta acttaagcaa tccccataat cgtctcgatt tcttcttcca ttgcttccag
    34981 ataatcactc gtaggcgagt acgcaagcgc tcatctatgc tggcgactat acttttcata
    35041 tttcccaatg agaaatagtt tatccatcct cgaatagaca aattcagttg ctcaatacgt
    35101 cttgttaggt ctatactcca tttcctctgt gttagtttct tcaatttaag cttaaatctc
    35161 cgaacactat cttgatgtgg acgacttttc caaccatctg atgatttcca gaacccaaaa
    35221 cctagatatt tcaactctct tggtctggta atcttagtct tggtcatgtt tactttcaaa
    35281 cctagccgtt tctcaataaa acgactgact gaatacatca cacgcttagc ggctgcctcg
    35341 cttccgaccg tatcacacaa tcatctgcgt agcgcacaaa tcgaagtccc ctcttttcta
    35401 attccttgtc caattcatta agcatgatat tggataagag aggagataaa tttcctccct
    35461 gtggtgtacc aactagtgtt ttataacgtt gaccattaat gataacacct gaatgaagat
    35521 acttacgaat caaggattcc gtatctccgt cttcgataat gttatgtact aaggacatca
    35581 atctatcttg aggaactgta tcgaaaaatt tctctaggtc tatatccact atccactcat
    35641 agccgtcatt taagtattct aagagcttca tgatggcttt ttcacatgac ctatttggtc
    35701 tgaaaccata actcgtatct gagaaatggg gttcacaaat ggggctcatg acttggacaa
    35761 tggcctgttg aatcattcta tccataactg ttgaaattcc tagttgacgg atgcctccgt
    35821 ctggtttagg tatctcaact ttaagaactg gttgaggctt atattttctc tgttttatca
    35881 gttccttagt caagcgccag ttttgtctga gataattatc catctcttcg atagtcattc
    35941 catcaatccc agctgagcct ttattggatt ttacttgatt gtaggcttcc agcatatttt
    36001 cgcgtgataa tatcttatct agcagttttg acatgtgcgt attcctttct tgttttggtg
    36061 cctgagggac atcttatatt ggtgaacctt catctagtca ttacgtgtca aagtccagtt
    36121 ctatcagacc actcatttta cagacacaag tgaagtagga ttacttcgat ctgtcgtttt
    36181 ctctttctag cgacagacct caaacagtct ctccccagac tgtttgagta ttcacccctt
    36241 cgctccactt ccactacaga agtttcctca ctactatggg ctcggctgac ttctcatgat
    36301 tcgttgttac tacgctttca gcgctcatga aacctcacgg gataagtcgt acatctttcc
    36361 tcgtttatac aagatatgag gacgttaaaa ggttacagtg aaaataggaa atctgacgca
    36421 gagtctttag actctagaaa gatttatctt tttcacacaa accttagtcc gaattcaatt
    36481 actctcgtga tttacacata taggttacga ctaccttttt ggactttaga gtttgaagcc
    36541 tccttatccg ctatatacgc cttactatca cgttcctgtt cgtagagcca cgatttcgct
    36601 atcccttcct ctgacgattc ttatttcctg cgtcagactt aaaacggtct atccccagac
    36661 cgttttaatc cgctacctca cgatagtcag gcttgggaat cgctattgg
//
LOCUS       DAVLBN010000016        36112 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLBN010000016 DAVLBN010000000
VERSION     DAVLBN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.016"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..977)
                     /locus_tag="VXC24_000781"
     CDS             complement(<1..977)
                     /locus_tag="VXC24_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0492927.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQN"
     gene            complement(1253..3358)
                     /locus_tag="VXC24_000782"
     CDS             complement(1253..3358)
                     /locus_tag="VXC24_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0492928.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(3639..3827)
                     /locus_tag="VXC24_000783"
     CDS             complement(3639..3827)
                     /locus_tag="VXC24_000783"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492929.1"
                     /translation="MLEIDLTVLIDLSCSYFVLIYSFEMVDRTDEVSSKHGFEVVDKE
                     KLMWFEEVFEECKKILVS"
     gene            complement(3967..4947)
                     /locus_tag="VXC24_000784"
     CDS             complement(3967..4947)
                     /locus_tag="VXC24_000784"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0492930.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(4949..7201)
                     /gene="pbpX"
                     /locus_tag="VXC24_000785"
     CDS             complement(4949..7201)
                     /gene="pbpX"
                     /locus_tag="VXC24_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0492931.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(7205..7522)
                     /gene="ftsL"
                     /locus_tag="VXC24_000786"
     CDS             complement(7205..7522)
                     /gene="ftsL"
                     /locus_tag="VXC24_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0492932.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(7534..8484)
                     /gene="rsmH"
                     /locus_tag="VXC24_000787"
     CDS             complement(7534..8484)
                     /gene="rsmH"
                     /locus_tag="VXC24_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0492933.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            8650..8844
                     /locus_tag="VXC24_000788"
     CDS             8650..8844
                     /locus_tag="VXC24_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0492934.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8860..9402
                     /locus_tag="VXC24_000789"
     CDS             8860..9402
                     /locus_tag="VXC24_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0492935.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            9413..9655
                     /locus_tag="VXC24_000790"
     CDS             9413..9655
                     /locus_tag="VXC24_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492936.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            9666..10001
                     /locus_tag="VXC24_000791"
     CDS             9666..10001
                     /locus_tag="VXC24_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492937.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(10111..11112)
                     /locus_tag="VXC24_000792"
     CDS             complement(10111..11112)
                     /locus_tag="VXC24_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0492938.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(11172..13073)
                     /locus_tag="VXC24_000793"
     CDS             complement(11172..13073)
                     /locus_tag="VXC24_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0492939.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(13095..13388)
                     /locus_tag="VXC24_000794"
     CDS             complement(13095..13388)
                     /locus_tag="VXC24_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0492940.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(13388..14206)
                     /locus_tag="VXC24_000795"
     CDS             complement(13388..14206)
                     /locus_tag="VXC24_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0492941.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(14193..14972)
                     /locus_tag="VXC24_000796"
     CDS             complement(14193..14972)
                     /locus_tag="VXC24_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0492942.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(14987..15478)
                     /locus_tag="VXC24_000797"
     CDS             complement(14987..15478)
                     /locus_tag="VXC24_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0492943.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(15489..16679)
                     /locus_tag="VXC24_000798"
     CDS             complement(15489..16679)
                     /locus_tag="VXC24_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0492944.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(16691..17125)
                     /locus_tag="VXC24_000799"
     CDS             complement(16691..17125)
                     /locus_tag="VXC24_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0492945.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            17398..18213
                     /locus_tag="VXC24_000800"
     CDS             17398..18213
                     /locus_tag="VXC24_000800"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0492946.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            18232..18873
                     /locus_tag="VXC24_000801"
     CDS             18232..18873
                     /locus_tag="VXC24_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0492947.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            18904..19905
                     /locus_tag="VXC24_000802"
     CDS             18904..19905
                     /locus_tag="VXC24_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0492948.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            19915..20544
                     /locus_tag="VXC24_000803"
     CDS             19915..20544
                     /locus_tag="VXC24_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0492949.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(20923..21308)
                     /gene="tnpA"
                     /locus_tag="VXC24_000804"
                     /pseudo
     CDS             complement(20923..21308)
                     /gene="tnpA"
                     /locus_tag="VXC24_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(21661..24740)
                     /locus_tag="VXC24_000805"
                     /pseudo
     CDS             complement(21661..24740)
                     /locus_tag="VXC24_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            24963..25439
                     /locus_tag="VXC24_000806"
     CDS             24963..25439
                     /locus_tag="VXC24_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0492950.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(25661..27874)
                     /locus_tag="VXC24_000807"
     CDS             complement(25661..27874)
                     /locus_tag="VXC24_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0492951.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(28275..28451)
                     /locus_tag="VXC24_000808"
     CDS             complement(28275..28451)
                     /locus_tag="VXC24_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492952.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(28831..30177)
                     /gene="celB"
                     /locus_tag="VXC24_000809"
     CDS             complement(28831..30177)
                     /gene="celB"
                     /locus_tag="VXC24_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0492953.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(30257..30763)
                     /locus_tag="VXC24_000810"
     CDS             complement(30257..30763)
                     /locus_tag="VXC24_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492954.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(30794..31108)
                     /locus_tag="VXC24_000811"
     CDS             complement(30794..31108)
                     /locus_tag="VXC24_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0492955.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(31118..33097)
                     /locus_tag="VXC24_000812"
     CDS             complement(31118..33097)
                     /locus_tag="VXC24_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0492956.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(33215..33529)
                     /locus_tag="VXC24_000813"
     CDS             complement(33215..33529)
                     /locus_tag="VXC24_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0492957.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(33659..33897)
                     /locus_tag="VXC24_000814"
                     /pseudo
     CDS             complement(33659..33897)
                     /locus_tag="VXC24_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
     gene            complement(33949..35385)
                     /locus_tag="VXC24_000815"
     CDS             complement(33949..35385)
                     /locus_tag="VXC24_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0492958.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(35575..35913)
                     /locus_tag="VXC24_000816"
     CDS             complement(35575..35913)
                     /locus_tag="VXC24_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0492959.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT        10944 a         7732 c         6029 g        11407 t
ORIGIN      
        1 ttattctgaa agtgaaacag caagagttga tagagctgat agtggtgttt caagtcttgt
       61 gaatagctca aaagcttgtc taaaatctct ttattggtta agtgcatacg aaaagtagga
      121 cgataaaatc gcttatcact cagtttacgg ctatcctgtt gtatgagctt ccagtagcgc
      181 ttgatagcct tgtattcatg ggattttcga tgaaactgat tcatgatttg aacacgcaca
      241 cgactcatag cacggctaag atgttgtaca atgtgaaagc gatccaacac gattttagca
      301 cacgggaaaa gttgtctagc taaatcatag taaggactaa acatatccat agtaatgatt
      361 ttgacgcgac atcggacggc tctatcatat ttaagaaagt gatttcggat gacagcttgt
      421 gttcttccct taagaacagt gatgatattg agattgttaa aatcttgcgc aatgaagctc
      481 atctttcctt ttgtaaaagc atactcatcc caagacataa tctcaggaag acaagaaaaa
      541 tcatgtttaa agtgaaagtc attgagctta cgaataacag ttgaagttga gatggaaagc
      601 tgatgggcaa tatcagtcat agaaatcttt tcaattaact tttgagcaat cttttggttg
      661 atgatacgag ggatttggtg attcttcttg acgatagaag tttcagcgac catcattttt
      721 gaacagtgat agcacttgaa tcgacgcttt ctaaggagaa ttctagtagg cataccagtc
      781 gtttcaagat aaggaatttt agaaggtttt tgaaagtcat atttcttcaa ttggtttccg
      841 cactcagggc aagatggggc gtcgtagtcc agtttggcga tgatttcctt gtgtgtatcc
      901 ttcttgatga tgtctaaaat ctggatatta gggtctttaa tgtctagtaa ttttgtgata
      961 aaatgtaatt gttccatatg aatctttcta atgagttgtt ttgtcgcttt tcattatagg
     1021 tcatatggga ctttttttct acaataaaat aggctccata atatctatag tggatttacc
     1081 cactacaaat attatagaac cgtttttttc agctggctcc ttctttttta tcctcaaaat
     1141 tctatcttat actcaatgaa aatcaaagag caaactagga aactagccgc aggctgtact
     1201 tgagtacggc aaggcgacgt tgacgtggtt tgaatttgat tttcgaagag tcttaggctt
     1261 tctcacgaat aaccaaaacg ccatcttcca tatctgcttc cagatgttta gtatctaaat
     1321 gatccaagtg gaagtctgtc accttatcac gaatttcttg ttcaaccacg cgacggagag
     1381 gacgaacccc catgacttcg tcgtaacctt cttctgtgat ataatcttta gccgcttgac
     1441 tgactaccaa gtcaatgtct ttcttagcca aggtttggtt aacttcagcc aacatcaaat
     1501 ctacaatctt agaaaggtct tccttagtca attgtgagaa ctcgatgact gcattaaagc
     1561 ggttgaggaa ttctggacgg aagaagggtt tcaaacggtc catcaattct ggtttatccg
     1621 catcttctgt caagttggct tcatagccaa atccagcatt tgaggtcgca ataatgacag
     1681 tgttcttgaa gtttactgta tttccttgac catctgtcaa acgaccatca tctagaactt
     1741 ggaggagaag ggtaataact tgaggatcag ccttttcaat ttcatccaag agaatgatag
     1801 agtatggatt gcgacgaaca cgttctgtta aggtattgct attgtcatca taacccacat
     1861 agcctgctgt tgtaccaatt agcttagaaa cagctgtgcg gtcactgtat tcagacatat
     1921 ccaaacggat aatcgcatcc tgggttccaa acatatcgag tgccaattgc ttagcaagct
     1981 ccgtcttacc aaccccagta gaccctacaa agaggaagct gccgattggg cgatttcctt
     2041 catcaaaacc agcacggtta cgacggatag cgcgagctac agcttctacg gccttatctt
     2101 gaccaatcac cttgtcttgc aagcgatgag ccatatcttt caaacgttcg atatctgaag
     2161 ctcccatttg cgatactggg atacctgtca ttcgttccac agattcagcc acatcgttga
     2221 cacttgcagt cactttcata tcttctgtgt ggttttcgat tttcttttcc aattctgcaa
     2281 tgcgtgtttt atagtttaga gctgcttcaa aatcttctgc ttcaactgct ttttcttgct
     2341 tgtctttttc cgtttcgatt tctcgttcaa cagcatgcac atctgttact ggatgttgag
     2401 ccgccaagtg agcagccgtt acatcgacaa ggtcaatagc cttatctggc aagctacgtt
     2461 gaggaatgta ttgaacagaa taatccaccg ctgctttcaa gacttcgtct ggcaagatga
     2521 cattgtggtg ttgttgatag aggtcacgaa ttccttgaag aattttaaaa gtattctctg
     2581 ccgaaggagc attgaccttc acttcgttga aacgacgagc aagagcagca ttcttcaaga
     2641 tggtgttacg gtattcgtct tgagttgttg ccccaatcac tgtcaattct ccacgagaga
     2701 gagctggctt gagaatatcc gcaagtcctt tagaaccact gtctccacca gtgctaccag
     2761 caccaagaat ttggtgaatt tcatcaaaga agaggataat attccctgct tctttcactt
     2821 cattgactaa gttttggaca ttttcttcaa agctaccacg gtattgagta ccagcctcaa
     2881 gacctgagat atcaatagaa ataatttcct tgttcttgat agcagcagga acatctccgt
     2941 tcacaatggc ttgcgctaga ccttcgacaa ctgctgtctt accaacacct gcatctccga
     3001 ccaaaacagg attgttcttg gtgcggcgtg agaggatttc agatgtttct tgaatttcct
     3061 tgtttcgtcc gataacagga tccaacttgc cctcacgcgc ttctgctgtt aagtttcgac
     3121 ctagttttgc aaggacaccg tcttgtttca tacctgatgc ctgttgtggc atttgcacat
     3181 cagtttctgc atttcctggt aattgaccag tcgcacgata gtgagcaaat tcctcaggtg
     3241 tgacttcgcg tccattaatt aagtaacggc gattttcaga actgtatcct cgcataccac
     3301 ccatcaattg gttaaataaa tcatccatgt tattaaaatt attaaagttg ttattcatat
     3361 tctttacctc tttttgttta cttagttatg attactgata ttgactatct ttgaccattg
     3421 ttttaaaaaa tttagactag ctagatcgct accctacgta ctatttctgg tttttctttt
     3481 tcaagcagga gtagactatc tttacttctg aagatttcta gatgaaacat agacccacct
     3541 ctttctattt tactttaaat aagtgttcta gtaaggcttt catttacctt acgttcataa
     3601 tatactacat tggtcagaaa aggtcaagag ttttgacttt aactgaccaa tattttttta
     3661 cactcttcga aaacctcttc aaaccacatc agcttctcct tatctacaac ctcaaaaccg
     3721 tgttttgagc tgacttcgtc agttctatca accatctcaa aactgtatat taaaacgaaa
     3781 taagaacagg acaaatcaat caggacagtc aaatcgattt ctaacaatat tttagaagta
     3841 gatgtgtact attctagttt caatctacta tattttgagc agcctaaagt tagctttcta
     3901 gtttgttctt tgattttcat tgtgtattta aacacaaaaa caccctgaaa catcagggtg
     3961 ccattcttac atcaaatata aaattgctag ggtcaggaga cttgctagaa gtcccactcc
     4021 ccaaaagaag aagtcaacct tccactcgct ccaaggattt cctttaccag acaatccccc
     4081 aagctcaaaa tggtgatgta caggcgtcat acggaaaata cgtttaccac ctgtcagttt
     4141 gaaataactg acttgcatca taacagaagt tgtttcaaaa acatacacaa ttccgataat
     4201 caagagagtc cattcttggt ggagagccat agagatagct gccagcatcc cacctagggc
     4261 caaacttccc acatcaccca taaagacctt ggcaggctta tggttaaaga tgaagaaacc
     4321 gagcaaacca ccaatcatgg caagaatcac tagaagaata tccatctgac cttgcacata
     4381 ggcaataact ccataggcag acaaactaat cacaacggaa atactagcta aaccgtcaac
     4441 accgtctgtc aagtttactg cgtttgaaaa accgactagc cagaaaagag cgaagaaaat
     4501 atagaaaaat cccaaatgaa ctggataacc aaagacagac aggatatcgc caccgcgctc
     4561 atagaaaaga tagaagataa ctccacctag aagctgaaga gctaattttt gcttaggatt
     4621 aagcccctca ttgattttac gaaagacctt gagaaagtca tctaaaaatc cgaccaagcc
     4681 atacaagacc aagatgaaca aaatcattcc cacattattg ctgaattggc tactaaatag
     4741 ggcgaaaaag aaagcaacca aaacagaagt aatcaagaaa accaaacctc ccattgtagg
     4801 agtcccagct tttgcctgat gctgtttgac atcttcatgc atctgctgtc ctgtaatttg
     4861 cgcctttcta taaaattgga taaaggccgg aattcctact aaagttagta aaaatgtcac
     4921 aattccagca ctgatggaaa taaacatatt agtctcctaa agttaatgta atttttttaa
     4981 tgtccttgat agctgtgtta gcacgaacat cttgcttctg cacagtagag cccgaacctt
     5041 gaaattcaag ttctatattg agccacttag caagggtctc agcagtctcc tttgtccaac
     5101 catacatatc tggaacttcc tctgctttat cagataagat aaggacttgc tgattcgggg
     5161 caagattctt cccttcttca gcagaactgt ttttaatctt cgttcctgtt cccacaacga
     5221 tgggttgtac aagattgcga cgcaattctt ctgctaaatc accaggtgaa atatccttga
     5281 cactaggcat aggataagga ctttgttgac ttacttgctc caaagcttta gctgttgttt
     5341 gaagattgag agagtctttc atagctgaag cccgctccaa gataggattg gcaaattctc
     5401 ccaactgaat acctgaataa tgttcaggtt gttggaccgt cacatacaag ataaaatcag
     5461 gattttcagc cggactcatc gatacagccg agaaaatata gtcggttacc ccgactagat
     5521 aaccaccatt tttctcgtca gcaatctgag ccgtaccaga cttgagggct acattttgcc
     5581 caggaacagt tacagttggc ttgcctgtgc tgtggttata catggttcca taaaccggat
     5641 ccgtccctac caaaaccatg ttagtccgag ttagactagc tgcatcttta gaaacaggat
     5701 ttcccacaat ttctttttga gatttccgag cagtttgatc atttggatca taaatggcac
     5761 taataaattt aggctccagc atgacaccgt cattagcaat agctgtaaag gcacgaatca
     5821 tttgcgtctg ggtcactgaa atcccttgtc caaatgagct ttgcgcaatg ttgacaatat
     5881 tatccgcagg aagctgacca gcatactcat ccgtcaaacc gaaacgggtc ggaactccaa
     5941 atttaaaacg attaagataa tcaagccagg tagcatctcc catcttttgc tcaaggaggg
     6001 tcatcccaac gttacttgag tgtgcaaaac cttgagaaaa agtcatcatt ctgccaccag
     6061 tcaatccttc attaacgtcc caatctcgaa tcgtggcatc tgcaattttt aactcactac
     6121 tattaaagac ttctcctcct ggaaaggtat tattatcaat agcagcagcc aacatcatca
     6181 ctttcatagt ggaacctggc tcatagttac tttggtaaag gatatcacgc caaacaaagt
     6241 cctctgtaat gccttctttt gtatctgcat caaaggtcgg tcgttgcgtt gttgccagaa
     6301 tttcccctgt tttagcactg accaaagtcg ctgtcatgta ctttcctttt accttctctt
     6361 gaaaagcatc catctgggtt tccataaagg actggagggg gctggaaatg gttgtataaa
     6421 catccttacc gtccatcgtt cgttgggaaa cttgttctgt tccgggtaca atattaccca
     6481 gacgatcctt ttcataggta ataatgccgt ctgtccctgc aagaatactg ttcaaggaac
     6541 tctccattcc agaggttccc agcaagctct tgcttccatc ttcattttca tggagctgag
     6601 ctaggccgat aaaactagaa gcaaattgtc cgtttgggta actacgattg ggactggttg
     6661 taaaatcaat ccccttgacc tctgcagctt ccaattcttt tttgatagac atcatattgg
     6721 cataggtaat cccatttccc tttgctccaa aggaaacttg cttgagatta ggttgcgaga
     6781 gttgctctct tacataggat tcttccatgt ccaaatactt atgaaagacc tctgcaacct
     6841 tgttaaattg tgttttttct acgtaaagaa tcttacccgt tgctgactta tagttctcat
     6901 caatgaccgc atagacatta taggaggttg catcctcagc aatcgggact ccatttcggt
     6961 cataaatagt cccacgtttg gcaggaactg tacgggtggt ttgatgaact ttcttagctt
     7021 ccttcgctaa atctgttcca aagcgagtgc ctgtcccaat aatgaccgca aaattgacta
     7081 aaaaaatggc aaaaacaaag acagataata aactcagact ttttccaact ctgcgtctgt
     7141 tttcagccgg cgatttccga tttttggtcg cataacggat tactcttttt gtccacttca
     7201 tatcttactc cgctattcta atattttcat tgtttaattg caaatcgtgt gaattggcaa
     7261 tttctttcaa acgttctgca cgtaatagtt cattgacctc ttgcttggca tcgtccaatt
     7321 cggttttctt ttcctctatc tgcgcattga tttttgtcaa atcattctgc acttgcaaga
     7381 gcttggtctg cataaaaata atactaatgg ctacaataag agtggttaca gcaatggaaa
     7441 agtaaaaagc tttttccaca cgcgaaaacc gtttaagttg catctgtagt atttgacctg
     7501 ttttttccat tttttctgcc atctttttcc ctcttacttg tgaatttttc tggccacgcg
     7561 caacttggct gagtgcgagc ggttattggc ttctaactct tccgcacttg gcaagattgg
     7621 cttacgggac accaattcca tcttgggctt gagatcatct gggatgaaag gcaagccttt
     7681 tggaacttca actgttgaag cttccttgaa caattgcttg gtcaagcggt cttctaagga
     7741 atgaaaggta atcactgaaa ttctaccatc cagagccaac atatccatag cctgctggat
     7801 ggactcatct gccgccccca gttcatcatt gacttcaatt cgaatagcct ggaaaatctg
     7861 cttagcagga tgccccttct tcttgagttc cttggcaggt ttgaccaact tgataatctc
     7921 tgctaactca gtcgttgtct caatcggctt cacttcacgc gcttgctcaa tcttacgcgc
     7981 aatctgttta gagaatttgt cctctccata cttgaagaaa atacgaacca agtcatgata
     8041 gtcataattg ttcaccactt catacgctgt cagactagca tcctgattca tccgcatgtc
     8101 cagtggcgca tcctttttat aagaaaaacc acgctcacgc tggtctaatt gaggactaga
     8161 cactcccaag tcataacaaa ttccatcaat ttcctgaaca ccagcttcgc gcaaacgtgc
     8221 ctgtaaatga cggaagttgt ccttgataaa ggtcaccatt cccttctcaa tgtaaggtgc
     8281 caagcgtttt tgcgcattgt caatggcatt ctgatcctgg tcaaaggcat agagatggcc
     8341 tttttcactt aatttactta ataaatactc gctatggcct gctccaccca aagtcgcatc
     8401 aacgtagata ccgtcaggtt ttacgtcaag catatcaatc gtttcgtgga gtaagaccgt
     8461 tacatgatga aattcttttg tcatatctta tctattttac cacaaatccg accagcttgc
     8521 acttgtcaga caaataggac aaggagacta ctatttcttc aaaaaatatg tcaaaaatac
     8581 ttgacacttt atgtttaaaa gactataata tagtcaaata tatacgacat aaatcagaaa
     8641 ggagaccaga tgaatcgtgt gaaagaattt cgcaaggaat tgggtatttc ccagctcgaa
     8701 ctcgccaagg atatcggtgt ctcgagacag actatcaata tgattgaaaa cgacaagtac
     8761 aatccaacct tggaactctg tctcaatctc gcccgcagcc tccaaactga cctcaacagt
     8821 ctcttttggg aggaagattt ttaaaaaagg agcaaactca tgaaaaaaga aaccttcact
     8881 gaaaaactga tcaaacgcac atacggtatt tctggtcccc ttgacgaata caaacggcgt
     8941 gaggccgata gtattgggaa ccaagtcttt atcgtcctct tttatctgat gattttcgga
     9001 aatattattc cactccttct ggcctataaa taccctcaag aagtggctct aatctatcct
     9061 cctctgattt tagtgattgc cctcatcgct tctggctatg tcacctacca aatgaaaaaa
     9121 acaggcatca cagtcattga accagatatg ctgaatgaga aagaaagcaa gcaactacac
     9181 taccctggtc tgaaagcagg tttgttcttt ggtctatgga tgttttttat aactcctctt
     9241 ctcagtatac tcatagatga aggtcaggac tattttcatt ctcttctcac tataagaaat
     9301 ggtgtatcaa gtattctcgg ttctattttc ttcggagcga gcatacagtt cctcatctcc
     9361 cgtcgcattg caaaaactaa gaaaaatcaa gatgaggatt aggaggaaac tcatgaaaaa
     9421 agaaaagaaa cagttacgtt atcctggtct gaaagcaggt tcgatttatg gaacagtgat
     9481 attttttata attccactca ttgataccct aacaagtgaa aatccaaatt ttatcagttc
     9541 tcttctaaat acaaaacata tttttaaaac tatactggga gctttctttt tcggagtgat
     9601 gatacatatt gtcgactcac ttcgtattgc aagagctaaa aaagaccagg attaggaggt
     9661 gccttatgaa atcactagct agactactga tcattcatgt ttttatcagt attttccttt
     9721 tcttcgccct tacttcagga gctatttctc atacagtttt actactccta ctcctctttc
     9781 ttcctgcgct caataaagga cttgagaaaa tacaatcaaa acggatacct gtcctcaacg
     9841 cagccctctt ctttctcctc atatcctttc cacaactttt aaccaaccct gtccaatgga
     9901 aattttcaat attcctagtc gtaaccatca tttcaagttt ggcctacttc tataactttt
     9961 atcaagtagt taaagaagta gatcaaaaac agttgattta ggagcttgct cccataattt
    10021 ctcattttat aggcaaataa tcccacctag cttgttctag gtgggattat tttatttctt
    10081 aacagagatt gcaagtcatt ttccttcatt ttagaaagtc gactctttcc aattcacact
    10141 acaatccaag acttgttgcc tttcttcttg attgcgacct tcaatctggt caatcaaaat
    10201 ctttgtagcc tgttgtcctt cctcaaagga gggctgaacc agcgtcgaaa cacttggaga
    10261 agaaaagcaa gtccactccg tattgtcaaa accaatcaac ccaacttgcg gcaagttata
    10321 attcaactct ttgataacgg taaagactag aggtagggcc caacagttag ggataaatac
    10381 cagagttttt tcatcgggat cgatttcttt ttgtaaaaat tctttaattt gttccaaatt
    10441 cgtatgctta tcttcaatgg ttagactggc gtgacgcata ttagcatctg ttaaagcatc
    10501 cacaaaacca cttgcccgct caatccgagt actcaaacga ctcgtatccg ctgtaatcaa
    10561 gagaaaatgt tcataacctt tttcgataca ggactgggtc atgtcataaa cggcatcata
    10621 gttattggtt ttaacccagc tagtccggtg ttcatagagc tgactatcaa aaaagaccat
    10681 tttcttcttt ttctcatcga tgatacgaga atattttcgg aaattagagg tcggctgaat
    10741 aataaagccg tctactccca agagaagcat gctttcaata taccggtcct cactctcttg
    10801 gctgtaatta ctatttccta tcattacctg gtagccattc tggctggcga tatcctcaat
    10861 tcccttaaca atttggtttg agaaactgtt ggtaatatca ccaatcaaaa caccgattaa
    10921 ttttgttcgt ttggagttta agctacgcgc aacaatgctc ggtttgtaat ttgtttcatg
    10981 aataactttt tcaatctttt cacgtgtctc ttgggacatt ttttcatatt tcccgtttag
    11041 gtaaaatgac acggttgttt tcgaggtctg agccatttcc gcaatgtctt ttatggtcag
    11101 tttcttctcc aatctaaaac acctcctact aatacttatt ataacatatt cactattcaa
    11161 aatgcctatt tctagcactg caagcgaatc attctctcat ttattttatc atatactaga
    11221 cattttccac gcatttttgt tccgtcaacg aggcacaatt tttcacctac acgaatatcc
    11281 tcgcttaata acagaatcag cttgtctgtt tcgtcatttt tcacttcaaa agccagagca
    11341 ttttccactt cacgatcatc tgtctggtag acagaatgac ggatgatttc aaaactctca
    11401 tgcgcaatga tggtataatc cagcatctga ttctcaaaga attggcgctt ggtgagtttg
    11461 ctacttcttt caagctcatt gtatttagga gaaatgatgg tatcttccaa atcaaaatca
    11521 acttcactcc atagtctcaa ctgattgatt ttcccatctt gataggtcac atccttgtca
    11581 aggataaact gagtcaacgc ctcatgctga ccttgacacc tgatgtcatc taccaagagc
    11641 cagacatcct ctaccaacat gaggattttt ctcttgtgaa gataaggcaa atcaggttct
    11701 gctgaccaat aagccccttc aatataatgc actccctccc tttctttatg gtgacaaaac
    11761 agggagtgag gatagtattc atattcccag gatcccgtga ttctttccgg agctttccca
    11821 tctacaatgc aggtcgaatg actccaagca ctctttaaga gataacgttc atatatctcc
    11881 cgataagaat aacgcccagc atctatgaaa ataggttggc cttgatactg taagcaaaaa
    11941 ctattctcgt cactatggct atgggcactt cctagcggac catttttgaa aaatagataa
    12001 cgatgttcat ccttaatgca gacatgtcca gagtcttcaa agatcatgga cttaggctgc
    12061 caagctctcc tttcaaattc ctgcagtcgc ttgacctttt ctcgccccag gaacaagagg
    12121 ctaagcaaat cgactttaac atccagaccg ttaagaaggt cttccttgtt caaaaccaca
    12181 gcagacagac tcaaaatttc tgtcgtttct gtagaatcgc tatcaccaaa agccaaagtt
    12241 cgtccatcta agcctgtcat catttgaata taggtcgcca tcttttccag caactctcgg
    12301 taactatctt gcaagtctgg aagcaagaga cacaaatcca gcaaggcttt ataaacctct
    12361 acatgataga gaatcgactg ttcaaactgg cttccatctc ctaaaatctg tgtctcaatt
    12421 tgctgtttca actcctctga agcaaaatgg taagcttctt ctagatccat cttatctgaa
    12481 aagaaataat agatagcaag catcggaatt gtttgtaaaa tcccccagtt actaagggtg
    12541 tacttggcgc gatagtggct tttcataaag tcaatctgct tttctagact gaccaaaatt
    12601 ttctctagtt ctttctcctc tagcaagtca aatttcaaga ggagcaagag tagtttcaac
    12661 caagtaaagg aacgaatacc cgtatccaag gttctagtca tcaaggattg aggagaaaat
    12721 tctctcacct gctcaatcca atcaaataga aagaacttgc acttttgaat atagctctta
    12781 tctccttcta ccacataccc tatcataaac tgcaagagat attcttgtcg attgagcata
    12841 taagcccatt ctggatcatc ttcaaatact tgatcccata ccatcggctg gatttgatgg
    12901 atttttgaac aaggctccat atcccaagga ctatcaaaca taaaacgatt gtccatcaag
    12961 cgttcaaggg aacgcttgac tttctcatag tcttttgaat agtgggacaa gatataatca
    13021 cgacattggt ttccatcgat tctttcaaaa aattgtcttc tttcttcttt cattatctat
    13081 taccagaaaa agaactactt aaaaagcagt tcttttgtct ttcccattac actttccttt
    13141 tctacataga tgaccacacc ttttgcaatc tgcaaggaga ccaagtcatc tttgatagaa
    13201 atgatttttc catgaattcc agacaataac aacacttcat caccagatgt taaagaagct
    13261 aaatactctt gtcgttgctc catctgtttg cgaagcaact tttgctgacg aatagaatga
    13321 aagcttgaca gtaaaagggg actcactgcc aagacaatca ctattccata aaacaatgtt
    13381 gtatccatta agctataatc ttaagccagc ttccgataat tccgatgata actgttaaaa
    13441 taacgagttt atatgttgtc catttctttt ctttgatcaa gtagtaaact aaaagtgtaa
    13501 atagggctgg tagaagagct ggagcaacct tatcaagcat tccctgaata cttacgatac
    13561 tttgtttagc gtctgcttta acttcccctg cagcaaaggt aatcggcacc ataatcttaa
    13621 cagatgtcgc tgccaaacca gcaattacgg ttacaccgat aatattggca atacgagaaa
    13681 tcgttgccat ctgctcgctt agtttatcaa tcacagttgt tcctagtttg tatccataca
    13741 gaccagttga caatttaatc gctgttaaaa tcgtattcat cgcaaggaag aacaagattg
    13801 gaccgacaac caagccttct tgagcaaacg aagctgcgat ggttgagaac aatggagcta
    13861 aacagaattg agaaagagaa tccccaatac ctgccaatgg tcccatcaag gccatcttga
    13921 tgctacgtgt ttcttttgtt ggtcgaccat tttccaacat tacaagatgc aagctggtaa
    13981 taaaaggcag gaagtgtggg ttggtattat agaattcaca gttttcttcc aaggcttggt
    14041 agaaaccttc ctgatcctct ccatagtgtt ttttcaaagc aggatacatc acattggcat
    14101 atcccaaccc ttgatagtta ctatagttaa atccattttg acaaaagaat gcccgcaaag
    14161 acgttttaag ataatcacgt tttgttaatt tgttagatcc agtcatcgtg tgcttcctcc
    14221 tctaccacat gatccgctgt ttttggcttg ttataaaatt caatcaaagc aaagatagta
    14281 cctacaattg caataccaat tgttgggatg tttagataag ctgcacaaac atatcccaac
    14341 aagacaaagg gaatcaactc tttcttagcc atcactgaca agatcatcgc aaaaccgata
    14401 gctgggagca ttttaccagc aactgtcaaa cctgtaagta ataccggtgg aatgtagtct
    14461 acgagtttca acaaggtatc cattgaaagg gcacccaagc aacccaaggt aaatccaata
    14521 aaggcaaaca accaaattgt tgcatttaga gtgaacttaa atttcttcaa attatggttt
    14581 ttcaagtgct tcatcgctgt ttcaggcgca ccagcacgta cagtgtaggc gaaagtttgt
    14641 aagaattgaa tcgccacagc aatcggagta gagagggcaa gagccgcttc tggactgact
    14701 ttaccagcac tagtgatagc catcaaggta ccaaagatac caggtccgat tgggtttggt
    14761 ggaacagtac ctccagcacc tacaccgaat cccatataag ccaattcacc aatagctccc
    14821 attgcaagag cagtaggcag atcacctaga ataattccga caccaaatga cagaacaata
    14881 catctattgg tgtaaattcc taacagcatt ccactaaaac agaaagctgt ccataatcca
    14941 attaaaatcg cttgaaatac attaatcgac ataacgatct cctcttttaa atatagtcca
    15001 taatgttgac ttgaacagct ccatcatttc ctgttggagt tgttttcgta ttaaatgtta
    15061 cttgatgagt ttggctcaat tccttgaggg ctgccttgtc ctcttcaccc aggaagatgg
    15121 agcgtgtcac ttgctcttta ccaggggcat tgtgaatgtt cccaatattg atttctttga
    15181 tagggacacc accttctacc aaggttaaag cgtcctttac atcctttaca acgataaaga
    15241 tcgtttgagc aggattagcc ttgtgaatga tatcaatcac cttttgcaaa gggaagaaac
    15301 gcatggcaac tgagtctggc acaactgttt tcatcagagt ttgttgcatc ttgtccgtgc
    15361 ttacttcgtc attggcaaca atgaccgtat tacaacctag gtattttacc caaagttgtc
    15421 cttgtccatg aatcaaccgt tcatcgatac gggtcataat aatatttggc attgtcatat
    15481 ttctcctcct accaatatag gttccagtct ttgtagaaac ggataagggc ttctaggtaa
    15541 tagtagtcac cccagatatt gccttcatcc actcctttac ctgaatgcca tgagtacaca
    15601 ccgtggagga gacttgtccc accaggggta aattgatcat ttgcataatg ttcgatcaag
    15661 gaacgaagca tggcatgcat agcatgttta taaatatctt tgtcagcatc cacctctggg
    15721 agatgtttta gcatttcatg aatcccacag acggcgatag ctgttgctga agaatctcgt
    15781 gattgatcac taccatcatt aaaaatcaaa tcccaatagg acacatgatc ttttggcaga
    15841 cgattcaaga aataattggt cacaccctta aacaagtcaa agcaggactc gtcttttaag
    15901 tgacgataag tcaaaggaat accatagact ccccatgatt gaccacgtgc ccagcatgaa
    15961 tcatcactat acccttgtct cgttacacct ttaaagggtt gacctgtctc aggatcaaaa
    16021 tagaaggtgt ggaaggacga agcgtcatca cggattacat tattagctga agcatagaaa
    16081 tgactttctg caatatcgta gtatttttga tcacctgttt cttgataagc aaagaataag
    16141 agttggatat tgagcaagca gtcgataatc aaacggtaat gctctttctt gcccaagtct
    16201 ccccaagctt gaataaaacc acctttttct tgatagcgtt caatcaactt atctgcagct
    16261 ttcaaggttg cttctctagc ctctccatct ccatttatct tatattcagc catacaagac
    16321 ggtgtgtaca agaagccgag atcatggtga tccaattcta ctctcttatt gacacgatcc
    16381 aggaaagaaa gaacattttt atgagcgatg tttttaaatg catcctgttg actgtattca
    16441 taagccaacc acagttctcc tgtccagaaa ccattggtcc attccgtgtt atccatgatt
    16501 ggatagacat tatcaaaggt agctggcgtc gggaaatctt ccttgaaata gtcaaggttg
    16561 agttctaact gccgaataac cttatcgatt gcctggccga cttcttcttt cgtcagaagt
    16621 ggtacttcta agaagcgctc aggcgatttt attttttcaa tcgtaacctt ttttatcatt
    16681 cttttaccct ttaaataccc gattcgaaat cttcttcctc ttcctctgca tccgttgaaa
    16741 acaattcttt accatttacg actccgccct gggccgccac tactgattta ttaacaacct
    16801 catcaaagct atgagccatt ctagcaaaga ctgcttccat taacatggct aagttcaaac
    16861 ccgagagaac attcattgtt ttggctggat tttctcccat tatggtagaa gaaaccttga
    16921 atggcgatcc tcccaagaga tcacttagga ttaaaacttc ttcttcattt gaaattgcaa
    16981 gtaagatttt ttgcttgagt tcatctgctg acattccttc cacaaagtca atcgcctcca
    17041 cattttcttg attgcctgca atcaattgta aagaactata aatccctgta gcaaaatgtc
    17101 catgccctac aagtacaatt ttcatctttt ctcctttctt gtttaggttt accggtttac
    17161 tttatattcc ccattgtaat cctttatttt tatcttgtca atagtttttt aaaaaaaaat
    17221 attagcgctt tcattatctt tttaaccatt ttaataggca gaaatttcaa aatcttccgt
    17281 ttttttagga aaacaaacct ttttataaat aaaaatattt atttattgac aaaaccggtt
    17341 tactagaata taatttggtt atagagaagt cttaacaaat ttgaaaggaa gtatcaaatg
    17401 acaaatacat cattctcaat tgagcagttt tctttaaaag gaaaaattgc tctcatcacc
    17461 ggcgcttctt atggaattgg atttgctatt gccaaatcct acgctgaagc cggcgctact
    17521 attgtcttta acgatatcaa tcaagatctg gtcaataaag ggattgaagc ttatcgtgaa
    17581 gttggcatcg aagcccatgg atatgtctgt gacgtgacag acgaggacgg tatccaagcc
    17641 atggtcaagc aaatcgaaca agaggttggt gtcattgaca tcctcgttaa taacgctggt
    17701 attatccgcc gagttccaat gtgcgaaatg agcgccgctg atttccgtaa ggtcatcgat
    17761 attgacttaa acgcaccatt tatcgtttca aaggcagtta ttccttctat gataaagaaa
    17821 gggcatggaa agattatcaa tatttgttcg atgatgagcg aactgggacg tgaaacagtt
    17881 agcgcttatg ctgctgctaa agggggcttg aaaatgttga cccgcaacat tgcgtctgaa
    17941 tacggtggag ccaatatcca atgtaacgga attggaccgg gttatattgc cactcctcaa
    18001 acagcacctc ttcgtgagtt gcaagaagat ggttctcgcc acccatttga ccagttcatc
    18061 attgcaaaaa cacctgctgc acgttgggga aatcctgaag atttgatggg ccctgctgtc
    18121 tttctcgcta gtgatgccag caattttgtc aatggccaca tcctatatgt agatggcggt
    18181 atcttagcct acatcggaaa acaacctgag taaaaataga aagaagatct tatgaaaatc
    18241 gcattaatca atgaaaatag tcaagctagc aagaatcaca ttatttacga tagtctaaaa
    18301 gaagcgacag ataaaaaaga ctaccaatta tttaactatg gtatgcgtgg agaagaagga
    18361 gaaagtcaat taacttatgt gcagaacgga ctaatggctg ccatcctttt aaatacaaag
    18421 gcagttgact ttgttgttac cggctgtggt acgggtgtag gggctatgct tgctttaaac
    18481 agcttccctg gtgttgtctg tggtctagca gtggacccaa ctgacgctta cctttattct
    18541 caaatcaatg gtggtaacgc cttgtctatc ccttatgcca aaggatttgg ctggggggca
    18601 gaactgaccc tcaaattgat gtttgaacgc ttatttgctg aagaaatggg cggtggctac
    18661 ccaagagaac gtgtaatccc tgaacaacgt aacgctcgta tcttaaacga ggtgaaacaa
    18721 atcacccaca atgatttgat gaccatcctt aaaacaatcg accaagactt cctcaaagac
    18781 accatctctg gcaaatactt ccaagaatac ttctttgaaa actgccaaga tgatgaagtc
    18841 gctgcttatt tgaaagaagt attagccaag taaagctatt ctaaaccaga aaggaactaa
    18901 tggatgacga aaatattact gtttggcgaa ccattaattc gaatctcacc attagatgcc
    18961 accagtatcg gcgatcatgt tgccagttcg acttattttg gcggatcaga aattaacatc
    19021 gcttgtaatt tgcaagccct gggtatctca acgaaagtct ttaccgcact ccctgccaac
    19081 gagattggag atcgttttct cacattcttg aaacagcacc aaatcgatac cagttcaatc
    19141 tgtcggcttg gcgatcgaat cggcctctac tatttggaga acggctttgg ttgtcgtcaa
    19201 agtgaagttt tctacgatcg taagcatacg agtatcagcc agattcggcc aaacatgcta
    19261 gatatggatt ctctctttca ggggattagc cattttcatt ttagtggaat caccatagct
    19321 atcggtcaag aggtccgtgc gatccttctc ctactcttgg aagaagccaa gcgccgagga
    19381 attgtcgttt caatggatct caatctgaga acaaagatga tttcagtcct agaagccaag
    19441 tatgaatttt ctaagtttgc acgttttact gactattgct tcggtattga tcctctcatg
    19501 attgatgacc aaaatctaga gatgtttcca agagacagtg ctagcctaga agaggtggaa
    19561 aatcgcatgc gacttttaaa agaagcctat ggtttcaagg ccattttcca taccctccga
    19621 tctagtgatg agcaagacaa aaatgtctat caagcctatg ctctggaaga acgatttgaa
    19681 gagtctgtcc aactaaaaac tgcagtctat caacgaattg gtagcgggga tgcctttata
    19741 tctggtgccc tttaccaact actccatcat tcctccctaa aaactaccat tgactttgca
    19801 gttgcgagcg caactctcaa atgcactctt ccaggagacc atctctccac ttccgcaact
    19861 agtattgaaa atttactggc aaatgcacaa gatatcattc gttaggagaa ttacatgacc
    19921 aaatcagata cgattattga actaaaaaaa cagaaaattg tcgctgtcat tcgaggaaat
    19981 acaaaggaag aaggactaca agcctcgatt gcttgtatca agggcggtat caaagctatt
    20041 gaaatcgcct ataccaatca gtatgcagga caaatcatca aggaacttgt agacttgtat
    20101 caggacgatc agagtgtttg tatcggtgca ggtactgtgc ttgatgccgt aactgctaga
    20161 gatgccattc tagctggagc aaattacgtt gtttctccat ctttccatgc tgaaactgcg
    20221 aaaatgtgca atctctacag cacaccgtac attccaggct gtattaccct cacagagatc
    20281 acgactgcac ttgaagccgg tagtgaaatc atcaaactct tcccaggtag tactctcagt
    20341 ccagcatata tctctgcagt caaggcaccg atcccacaag tttccgtaat ggtaaccgga
    20401 ggagtcggcc taaacaacat ccctcaatgg ttcgctgctg gtgcagatgc cgttggaatt
    20461 ggtggcgaac tcaataaact cgcttcccaa ggcaactttg accgcatcag cgagattgcc
    20521 caacagtata ttacactcag ataaaatcat aactacccgt ctaacgggtg gtttatctca
    20581 gagctataag cccaaatcat cagccagcgc ctaaagacgc tggctttcac gttgttcaag
    20641 ccttattgct cttgactcgt cacttgcctc tttaagagac tttggtatta cttaccacta
    20701 tccctaaagg gatcctcata ttcttttaca ctcaatttat ctagtgctat agtagattga
    20761 aactggaata gtatacctct acttctaaaa cattgttaaa aatcgatttg actgtcctga
    20821 tcgattttgt cctgttctta tttcatttta ctatatatca tactttacta gttctcaaat
    20881 tttcatactc gtgaagaaat catccactcg ataatttctt taatcttgac tatatttctt
    20941 aattgtggct tcattaagcc ctactggact tacataataa ccttccgccc agaaattccg
    21001 attcccaaac ttgtacttga gattggcgtg tttgtcaaac atcatgagtg cacttttgcc
    21061 ttttaaatac cccataaaac ttgaaacact tagcctcgac ggaatactga ctaacatgtg
    21121 tacatggtct ggcattaagt gaccctcgat catttcaaca cctttataac tacacaagcg
    21181 atgaaatatt tcgcctaaac tacttctata ttgattatag atgacttttc gtctatactt
    21241 aggggtgaac acaatatgat agaacacatc cactttgtgt atgataaact atgagtcttt
    21301 tgtgccatat tttttctcct ttcgctttac aattggattg aataccttta ttgtatcgcg
    21361 tttggagttt ttttggtata accttcgacg cgcacctcac ggagcgagac ggacttatat
    21421 agtggagtga aataggatac gaacaaattg attaggaaaa tcaaatgaat ttatagaaat
    21481 cttttagcag ttataacgtt ctattctagt ttcaaaacgc tatagtcaca taataatgaa
    21541 gtaaaaaagg ataagtatca acttatcctt ttttaaaaga aaaatccgaa gatatttggc
    21601 cttcttcgga ttttttctat tttccacagt ttcatgtaat tcatctagat gatgaacaaa
    21661 ttagttgttc tttcctctac ggaatagata aaatgcccca agtagcaaga accctagact
    21721 tgccaagatt gactgacctt ctcctgtctg agggagattc ttttgatccg aatggttctt
    21781 ttcctcttca gatttttcct tttcttttga attctgtact tgtggctgag ctgcttgctc
    21841 tagcttttta aagacttcct gatctggagc tgattcctgg gtttcaggat tatagtaggc
    21901 aatcttatat tcatcccctt cttttcgaat ggtatagact ccacgtttca aaacttggaa
    21961 ttggttggaa atagtagaga cagaatcatc atatttcaca atgccccaaa ctccttgttt
    22021 agcatcataa acagactgaa gggtttcgct attttcgatg aggctacttt ctaactcttt
    22081 tatcatttga ttgaaggtgg cacgatccac gttaggaatt agcatatagc cataagaatc
    22141 tccattttgc ttatgagcct gactaatcgt aagaaattca ttttcaactt ccttgtctga
    22201 ctgtccttca ttgatatcct tccaggctcc cttttgcaaa gccttactca tactgattga
    22261 actcttctta aagaaaaagt aaccaatatt ctttttcgaa tcggacgatt ctaaaaagac
    22321 actttgggtt tcaggataat ccttttcttg ttctgtaagg gaggcttctt tatcattgac
    22381 atagacttta tatggattac ttgattccag ttggtgaaat ccatggttgc tgtcgcattg
    22441 gcatcatcta gtttgctcgt tccaacgaaa gcagacggta gaactttacc tgtatcgcta
    22501 tccgctctct tagcatccgt ctctgttgta ccaggcatct tatatggatt aactgttggc
    22561 cagtagccat cgctatagtg actcaaatcg ccattgtaaa gatagaacat cccatcactc
    22621 gtataccaac catgtttatt ttccttgttc atgtgttcgt aattcaaggt acgactggaa
    22681 aagagtgaca agccaaatcc aaaccctttc tctgcattgt acatggctgt tttatccatc
    22741 ttgttaaagg cagataggta acttgttctt ggaacacttg cgactcctgc atcacttaac
    22801 aaggattgca tcaaactgat atccttataa gtcttcaaat tcttaaagac atcataataa
    22861 ctatccgatt gaacaatggt cttcacaaga ctctgcaaac gttgtttggt ttctccttca
    22921 gacatatccg ctattcggtg aatccctctt agtacttcta ctgcggccac gtgcccctcg
    22981 ctatttgcac gactgatcga gcgtccacga ctcatatcca tcagctctcc attcaccagc
    23041 aaaggagcaa acgatttatc aatccagtgg tacatggttt gcattttatc tttatcgatt
    23101 ggattcttgg tcttttgaat gactggcaac agttgagaca ggccatcaat caaaacattc
    23161 ccataagcac ccgtataggc aacattggta tggtcgatat aggatccatc ttgataaaaa
    23221 ccttcacctt ggtctaccaa cttgaacact tgctcaatcg agcgaatggt agaagaaatt
    23281 tcttgatcat ccttacgcag taaaccagct attactttta ctcttcccat atcaactaag
    23341 tttccaccta gagccttaaa tgggttatca gtcgtctttc ggaaatgttc gggatctggt
    23401 acaaattttt caatcacatc tgtatatttt ttaatttcct catcagagaa gtattctttc
    23461 atcagagaca aggtattgtt gatggcacga ggtgtaccga tttcataatc ccaccagttc
    23521 ccaacaatgc tcttttcact attgtagaca tgtttatgca tccattccat ggaatccctg
    23581 actgttcgaa cgacagtttc atcttgataa taacgagaag aaggattggt cacttgcttg
    23641 gccatctcct ccaatttccg ataagtggca gtcagatttg cagacatttt ataatttgaa
    23701 aatttttccc acaaataggt gcggtccgcc tgacttgaaa tactagatag gctatcagct
    23761 acctttcctt ccaattcctg gtttaatttg gccatctgtt catttttaga atcatagtat
    23821 tgattcccag caatgatgcc attccagtca tccaaacggt ctgtgtatgc atccttaaca
    23881 gaggctagaa tcttcaaagg aatctttttc acttccttgc catctttact gacaatgaca
    23941 ttggttgtcc cttccttaag aggttctaaa attccatttt tgactgaagc aacgtcagga
    24001 ttttctacct tataagtata gtccgcaaga gaaaaaacat gtttttttcc aattggtaaa
    24061 tcaatctttt cctcaagctg tttatctgtt tgagaatcct cagaaagctg ggctgctacc
    24121 tctaccagct caatatcctt aaaggaaaca gtcccagttc ctgtttcata gaataactcc
    24181 agcttgattt tatcaacatc taaagtcggg ctatagtctg cttcaatggt ctgccagtcc
    24241 tttgttcctg acgtcgttgc agaattccac aatcgcttgt ccttaccact ttcctcaatg
    24301 atacgaactt tggcaatccc gactttatga tctgttttaa tcttgaaacg cagtttatac
    24361 tttttcttag cttcaatagg aaccatacgg tgaaccgctg cccttaattt ctcagggctt
    24421 gagatagtga tagccccatc cttagcctca atgactcgag ttgaggcatc tgcagaacta
    24481 ttcttctggt ctacccaagc tgaccacccc tgagctttgc ttcctgtcca cggactgctt
    24541 ccgtcctccg tctgaccaaa atcaccattt tcaactaaat tttttgtatc cctttgctga
    24601 tactgaactt ccttctggct ttgctgaatg gtattcgtag tcgtttcttc cgctccaact
    24661 gtcatataat ggtttaataa aaatcctgat aaaacaagtg aagacaaact cacaatgagc
    24721 ttctttgttt ttgtttgcat gtatacactc caataaacat attgtaaaat caataggaac
    24781 taaatctcaa attagagatt tatagcaact aagtaaaccg gtttaattaa attataccat
    24841 ttttaaagtt atttgtaaac ggtttctatc atattgaggg cttattcttc aacaatatct
    24901 tccatccgac tcgacgaaaa aagtaaaaac tgttacaatg tagaaaaaga aaagaggccc
    24961 tcatgacttc actttatgat ttttccgttt tgaaccaaaa caaccaagca actcccttgg
    25021 atagctatcg tggcaaagtt ctcttgattg tcaacactgc tactggatgt ggtttaacgc
    25081 cccagtacca gggacttcaa gaactctatg aacgctatca agatcagggc tttgaaatat
    25141 tggatttccc ttgcaatcag tttatgggac aagcacccgg cagcgcagag gaaatcaacg
    25201 ccttctgtag cctacatttt caaaccacct tcccacgttt tgccaagatt aaggtcaacg
    25261 gtaaggaagc agaccctctc tatgtctggt taaaagacca gaaatccggc ccactaggaa
    25321 aacgagtcga atggaatttc gctaagtttc tcatcggtcg agatgggcaa gtctttgaac
    25381 gcttttcttc aaaaacagac ccaaaacaaa ttgaagaggc gatacaaact ctactataat
    25441 tcacaatctc actatgatta ggtttccttt aacctgatga atagtgagat tttttgattg
    25501 gctttgactt aaatagaaaa acaccccatg atatgaaaca tgaagtgttg taaagtctat
    25561 gttgtaggtg cttatttcac attttcaatg tgaccagtga taacgaatac catacagaat
    25621 cttcatatac actaaacaaa tgactttcta attatatcaa ttagttttgg ctagtaaata
    25681 tcatttccaa caaacgccct ctcaattcct tatcctgatg atgcaagata ttcattaagt
    25741 catgagagtt tttcgcattg atgaattgat ttaacaatct atcttttaat tcatatggaa
    25801 gagaagctgt ctttagtagt ctaaaaactt catcatttaa agatattgtt ttattatctt
    25861 tacattcaaa tctagctgta tcattcttat ttggtaattc aattatagac acattcgttc
    25921 ctttaaaatg aattctatgc cttctattgc ttggaacgat actagaatct ccttgtaatg
    25981 ttaactctac catccccatt tcccaatcga ttgataatct tgttttatat ctttgaccat
    26041 tttgatcttc aagcatttca aaagaatgtt gtttgcctgg gaatacatac caatctacaa
    26101 cttcaggtaa atcaacaccc atatctatct cagaaccaac caagggaatg atcgcaccac
    26161 tttttgcaaa cacaggtata gtcgaaatgt ctctataaac actcaacttc acaccacctg
    26221 tatatttttt ctctgaaaag aagtcatacc attcaccttc agggaaccat acatccactt
    26281 ttgcagattg gaatgccaag tccatctttt ctacaatggg agccaccatt agttctgttc
    26341 caaaaaagta ttggtttgga acattatagc tctcatcatt ctctgggtag aaataataca
    26401 ttgggctgat taatggggca ccttcctcgt gtgtctttac attcatagtg tatagatatg
    26461 gaatcatctg atgcctcaaa cgaaggtatt tcttcataat cttagatgtt gtttctgaaa
    26521 aaaaccaagg ttctttacta ttaaaaggac ttctagaact atgtaatcga gtgatcggac
    26581 taaaaacacc aaactgtagc catctagttt gcagctcttc gtcataatct cccagcatgt
    26641 gcccaccgat atcatggctc caccaactat aaccgatatt agatgctgtc gctgtaaaat
    26701 aaggttgaaa tcttaaggaa ttccaactaa taatagtgtc ccctgaaaaa ccaacagggt
    26761 agcggtggct accaggacct gcatatcttg ataaaatcaa accaccttct gcatttttac
    26821 aactatcctg ataatgataa tggtttaaaa gccatagtgg atccaatatg ccttgagtcc
    26881 cttgttgcca gtcaatccac caaaaatcta ctccctgctt ttctagctca taatgaacat
    26941 ctttaaagta ggcttcccta aaagagggat taaaaaaatc aaaaatggca ggttcttcta
    27001 gttctacatt taaccctaat cgtttggcga cttgaggata agcttcttca taagcccgta
    27061 taccatcagc aggatggaca tttaaagaga gttttaactt tctatcatga agttgttgca
    27121 ataactgttc tggattaggt attaagtttt tattccaact atatcctgtc cagccacttc
    27181 caaaacgagc tggaatgtca gttatatgcc aatccatatc taacacaccg atagataatg
    27241 gaattttctc tgtttcaaat ctgtctatta aatccaagta ttcatccgac gtataaggcc
    27301 aatatctact ccaccaattc cctaaagcat atcttggtaa caagggtgtt gaaccagtca
    27361 aatggtaaaa gtctctgatt gctcctctat aatcatgccc ataggcaaag aaatagaggt
    27421 caatttgatt ttctctctca atataaccag actgttcatc ccaaataaat ccttgagaat
    27481 catccaataa ggctatacca tttcgactaa taattccatc ttctaatggg attgctccat
    27541 ctgccttatc cagagtccga gctgttcctt ttaacgtttc aatcgattca ccaaaatacc
    27601 agcgactacc atatacggca aaatttcctt ttaattctat aaataaattt tcggcgttaa
    27661 attctccttt attaaagtgc agatgaaaat agtccgtcat aatatctagt acgtttgatg
    27721 tctcgatata atctaacgaa acttggccaa aatctctatt atagataagt tgtgtagttc
    27781 tatcctcaaa actgccagtt ttagagtatt ctaaccttac tagcttgtct gttaatacag
    27841 agatgcgata aaactctccc ttaaaaattt tcaatttgtt tccctccttt tatggtagca
    27901 taaaaacaga acgcaccatt tttgatgcgt ttttcattat tctgaatgca atgttctatc
    27961 tgttatatct atgacaaata atagtcaatt gaaaaaatgt agtggacaaa atatctttta
    28021 acaaaccaag agtttattaa agagttatca cttttcaact tttctaagct tatgcagttg
    28081 tgaaacaaac tacttttaaa ctattaacta agataggatt gataaataat ttcaaactct
    28141 tactagcaat catacaatat tcaagctcac gtgctttttt ccttcctgct tatttcttag
    28201 aactgaagaa cccggatcgg tatataaatt atccggatca acatagtcat aagattcata
    28261 acagttgcgc ttcattaagt catccccaga gcaagagctt catctcgtaa tttttcaaca
    28321 tcactaaccg taggtcgcca tccttcaatc atatttgtac ttaaagcata ccaaacactc
    28381 ttaaaaacgg atcggttttc aaaagctatt cccatgattg tcatcttttc tttatctata
    28441 tctaaggaca tatgctacct cctttagata cattatacca tgtttctatg tagcttttaa
    28501 aaattttatt ttgtttgtca tatctaagtt ttcagcatgc ttatcctatt ttataagcct
    28561 caaacccaaa tataaaacgc attctttttg cttttttact attgtatcgt attctacgat
    28621 aacatacttt actttattgt ttttttaaaa taacagcagt tccctgttta tcaactattc
    28681 gaactacttt ctattttgct tcatacccta catagcgaaa aaatatgaaa aagcagagaa
    28741 gaatatctta aaaagacctc ttcactgcta atgttaacgc tcattattta aactatatgg
    28801 attctatcat cgagtatact tttttactta ttagatacct tgctcttctt tcaccaattt
    28861 ttgatcatat acacggatga atggaagata gactaggaat gctgcaaatg cacatactag
    28921 agcaactaat acagctcgaa gatctgctgt ccctaagaaa gctccaatcc ctactggagt
    28981 tggccatgga acctgtgcga taattggctt aataaagttt agagaattcg ctacgtaata
    29041 aatagtagca gtaaccattg gtgctaaaat aaatggtata gccaaggctg gattatagat
    29101 aataggtaat ccaaaaatta atggttcatt aatattaaat aaggctggaa ctacagatgc
    29161 tcgtcctatt gctttaagct gttcagattt agaggcaaaa gcaatatata aacatagtcc
    29221 taaagttgca ccagaaccac ctgcaattac aaacatatta gaaaattcac ctgcaacagc
    29281 gaagtgcccg ccagcagcat tttcagccat gttagcaaga gcaattggac taacaaatgc
    29341 aaaaacaatg ttcgcaccgt ggatacctac aatccaaagt agttgagtca gtaaataaat
    29401 aatcattaaa ccaatccacg aattagtcag attggataca aaaccaaatg gaattgcaat
    29461 gactttaaaa acatctgttc ccattgctac aagaagaccg ttgataaaga taacaacaaa
    29521 tgcaacaaca aatcccggaa ccaaagcggt aaatccacga gaaactcctt ctggaacagc
    29581 ttcaggcatt ttaataaccc aattatgttt aacacacata cgataaataa taacagtcac
    29641 aattgccata atgattgcgg taaaaatccc tgttgtccca aaacgtgcga ctccatttcc
    29701 cattgcccat ccatctgcaa ttactgcacc ttcttttaga cttgtcacag tcttcatcat
    29761 tccaccatca aaaatgattt gcggtactgt catgacaaaa gccatcaagg caagcaaggc
    29821 accattaaga ggattcatat tgagttcttc ttcctctgca taaatttttg tcaattcata
    29881 tgcaagtgat agaacgaaat aaagagatag agaacccata gtcgcatagt ttgcaaccat
    29941 gtaaagtgat gtgaatttat caaatgaagc agagaaaata tctgccacaa ttggccaaaa
    30001 tgagaaagct tgtggcaaaa tactgaatac caaaaacatt gatcctacaa tagtaaatgg
    30061 tacagcagcc atacctgcag ccgtgatagc acgcactact ttaaactgag caagtttgcc
    30121 cattggtccc ataacatggt tttcaagaaa accaaacaac ccgttttgtt gatccataaa
    30181 tagacctcct taataaaaca taataatttt tactttctaa agactagttt caaatacaaa
    30241 ttatactaga tcaggattat aaactaagtg agttcttttc caattggaca aattgttgat
    30301 aagccttatc tgttcgttta taaatttttt taattcttct aatgtctaac aaactcagaa
    30361 ctaaacctaa tagaagaact acaaaaacaa ataaacgtgc tacttggtta ttttcaaaaa
    30421 tcggaaaaag attcttaaac caacttgtcc aagttaaaac aagtaatcct attgaaataa
    30481 gcatttgtat tctaacaaac attagtgtta ttcccaactt ttctttccta tttccataga
    30541 gtttaaattg ttcaacagtt gctaaaatag aaaatactat gagcataatg gggaaaataa
    30601 taataggcga gggattaata aactgattca aaagccaata aatattccca aaaaagaaga
    30661 gtgctattga ataacgtaga agaagatatc gattaaaaaa agtattagtt agagccatct
    30721 ctcgacgttg ttgttcaatc ttttgtcgtt cttttttatc catatcattt cctccttata
    30781 taacaacaca tatttagtta actttcttat aaagagctaa catttccttt gctacttcta
    30841 ataatgtcat agtggtcatt aaatgatctt gagcatgtac catgataatt tcaattttaa
    30901 tttccactcc acttgcgtat tcttgcaaga gtttggtttg tgcatgatgc gcttcaagaa
    30961 ttatctcatt tgattgattt aatttacttt ctgcatcatc aaaactacct tctctcattt
    31021 ttgcaaatgc ttcatgtatt tctgaccttg catttcccga atgcaggata atttcaaatg
    31081 ctgcaacctg cagttcctct tgattcatat gaacctccta ttttatcttc tcaaatatgt
    31141 taataaaatc ttcaaagtta ttgcaagata ttagctgatt ttgcaattca tcattctctg
    31201 tcagagagac tatcttttta gtcacagttg ccaaaccttc gttcccatat attgatggag
    31261 atagaagaaa tactagctgg acatgtgaac tttgattatc ccagagtaac gaatctttac
    31321 aaattgcaac cgaaaccttt ccctctgtac caaagggctg aataggatgc ggaactgcaa
    31381 ttttttcaga aaaaacaact gaacttaatt cttcgcgctg tttaattcca taaagtaaag
    31441 attgttcaaa ctcatttgat tcaccaacag ataaactctc aaccatcttt tcaagtaaat
    31501 ttaccttgtc tgattcagta catattaaaa agttttcttt actaaaatac tgtctaaagc
    31561 cgttgttttc aaatttgtta atctttgatg attgtacata actagaaact tgcatctgat
    31621 ccatagcttt tctaatcatt tccatctcat cactcttaag aaacacacta actttaaaaa
    31681 ctgggatttg aaaatataga tttgataaat caacagctga cactataaaa tctattcctt
    31741 taagtttttc ttgattcaat tcataatagc ctattacatc aacaacttct actcgcttcc
    31801 caaactccgt ttccaaacga tttcttaaca tttgggctgc accaaatcct gttgcacaaa
    31861 tagcaagaat attaaactta gtactctctt tgctacgttc catagcagct aaaaagtgaa
    31921 gacttacata tgctacttca tcatctgata ttgtccactc caagaacttg tccatatttg
    31981 caagaatttc tctagtcata aagaatatat cactataatt ctgtttaatt tcatctacca
    32041 aagggttatt taaggtaatc cggctttcta aacgtacttg tagtgtcatt agatgagtta
    32101 tcaatccttc aattagttgg aaatctgaag aaaagttata catatcatct aatcctaaat
    32161 tctgaaatgt tttaaataaa gattttttta aaacttcttc agaaatattc ttctgatttt
    32221 tttgacattg ttgactctta gctaacaaat gcaaagtaat gtagtctatt tcctgaactg
    32281 gaaattcctg atttgttact tctcttactt tagaaagaat tctttgggca acctttctct
    32341 ctattgcatc atcagtcatc tgacagtcta tattttttat ttcaaatccg gattttaaac
    32401 gaatcacaga caatgctatg tgaactacta agttctgtag tacaaaatca gatagtttta
    32461 ggttggcctc ttggcattca tccaaaacaa ttctagcaaa ttcttctaat ggaacagttt
    32521 gatcaaaaaa gttaaatttt acatagcaat gtattgtttt aaaaaattga ttctctagga
    32581 aataatttat gataaaacgt cgtttatcac gttcctcgcc tgagacataa actcctttat
    32641 tcgccctact ctcaatggac aaattatact ctgataacat cactcgtatc tttctgaaat
    32701 catgagataa tgttgaacgg ctaacgtaaa gttcatcagc taaatcatca aaaagaactg
    32761 gaacttgctc aaataataat ttatttaaga taaatactaa acgatcatca ccttttgaaa
    32821 ccgcagtttt cgtatagtct tcttccagtt cataagtttg tctaaactcc tggtaagcgc
    32881 cttgattctc aaaaaatatt tgataccctt gaccttgttt tgaaatcaac cggactcctt
    32941 gaataatcat tgtcttctca attaatttca gtacattacg gacagttcta tctgaacagg
    33001 ataaatattc tgccagttct ttgcttgtaa caaaacgttc cttatttttt attaaaaatt
    33061 gaaggatatc tttctcttta atgtttaaca cattcattcc ctcctaaaac gtatgttttc
    33121 atatattgaa gcatattata cacttaaatc aatttatatc aaactcaaaa caatttatct
    33181 taacttaaat atttattgac atttcatgtg ttcatcaaat attctcaaga atcaaattag
    33241 ccattttttc aattcccatt ggaataggaa tataggcttg aggaggtatt tgtacaactg
    33301 gttttcctgc tttagaacca gcctcttcaa attgcttaaa gtacattttt gtttgagggc
    33361 tgacaagata caaatcaaaa gctgctgctg cgatagcttt ccctccttca gtagcactaa
    33421 tagcatcaac tacaatatct ttcccttttc cttttagaaa ctctgttgtt ttctgtgcca
    33481 taagtgatga agacattcct gctgcacaaa taattaaagc ttttgccata atattttctc
    33541 cttttcttaa atccaatcaa agctgtgcta agttgactta tctgttatct atttttatta
    33601 taaaataaag cgtttccaat gacaattccc tcattttcct aaatgatatg gaaaaaaatt
    33661 atttatactt caatttataa aataaaatta ttcctgagag tagaaatgaa acactatttg
    33721 ctaaaatcaa aggcaagtct cctatacgaa taccatgagc aagccacaat gcaatatcaa
    33781 taacttgcat aacatacata cctagagcaa tagatcctgt gtcctttgtc ttaactatac
    33841 gaaaaacttg tggtaaaaag caaatgttgt taaaattgct gcaatacttc caatcatatg
    33901 tcatcccaat atgctaaaca aactgagaat aatctcagtt tgtttatact attctactga
    33961 ttcaccgtta gatgaaataa cttccttata ccagccaaaa gattttttcg gggaacgatt
    34021 ataacttccc ttcccattgt catctttatc tacataaata aaaccataac gtttccgcat
    34081 ttcaccggta ccagctgaaa ccaaatcaat acatccccat ggagtataac ccattaaatc
    34141 aacaccatct tcaactacag cctttttcat ttcacgaata tgggcaccta gatattcaat
    34201 tctataatca tcatgtacca taccatctgc tgcaacttga tctatagctc caaaaccatt
    34261 ttcaacaata aagagtggta agtgatagtg gtctgtaaac caatttaacg cataacgtaa
    34321 accttctgga tcaatttgcc actcccattc agaagcctta acataattat ttttcactaa
    34381 atcttctgtt tcaagataat caaaataagg attattttca cgatgagagt ctatagcaaa
    34441 ggacatatag taactgaaac caatgtaatc tacagtccca ccaagtaaat cttctttatc
    34501 ctggtcagta aaatcaactg aaataccttt tcgttcccaa tacttgaaaa tatgctcagg
    34561 atatttacct aaaacatgca catcagcaaa ataataacgc ttctgcatag ctttcattgc
    34621 cattaagata tccttaggat tgcaagtagc tggataaatt ggacacatcg caatcataca
    34681 acctatttga aaatctggat taatctcatg accaattttt acagctcgtg cagaagcaac
    34741 tagttcgtaa tgtgctgctt gatacataat tgcttctcta ttatcacctt cctcatatac
    34801 aatacctgag ttagtaaatg gtgcaaaatc ttcctgataa ttcgcttgat tattgatttc
    34861 attgaaagtc atccaatatt taaccttatc tttgtaacgt ttaaatacga cttctgcaaa
    34921 acgagcaaag aaatcaatca atttcctatt tttccaacca ccatattcgg tcactaagtg
    34981 ataaggcatt tcaaaatgag atagagtgat gacaggttca ataccattct ttaagcattc
    35041 atcaaaaaga ttatcataaa actgtaatcc ttcttcattc ggctctaact catcaccttt
    35101 tggaaagata cgtgtccatg caatagaggt acggaagcac ttgaatccca tttcagcaaa
    35161 aagtgctatg tcttctttat aacgatgata aaaatctatc gcctcatgat ttggataata
    35221 tttaccctct aaaactcccg aagtaatttc acgagctact ccatgacgac cagcagtcat
    35281 aacatcagca acactaattc ctttgccacc ttcttgccat ccgccttcaa gttgatgagc
    35341 agcaacagca ccaccccata aaaatctatc tttaaaagta gtcatctttt ttcctcctga
    35401 ctttgatact cttattataa acctcaaacc aaaaaatgaa aacgtattct ttttccttat
    35461 tgttaaggaa agaagtaatt tttaatggaa atagaacaat atcttcttgt attctcgtaa
    35521 tgatatcttt acgattttca atactttcaa actacaaaaa ctctcacaat aattctaatt
    35581 ccctgtgtct ataaacgact tatcgctttc tggcatccca gaatcatctt ctatataacg
    35641 ttcaacttgc atctgcaagt gatatttttt tcttaaatct aagattttct gcattgtctt
    35701 tgattgataa tgtttatcta aagtttcttg atttatccac tgatcaataa ggagaatagt
    35761 tccctctttt tcaattggta aaaaatattc gtatttcaag ttaccttttt gatttctaat
    35821 ttcttcaaca aggccactat caagcatttc tcttgcaaac tttattgcac tatctccatc
    35881 acctttataa tatacatgaa tagtcaatgt catcttatat cctccaaaat catccttcaa
    35941 ttttaaaaaa acaagtttag atgaggatct aaacttgttt tttatgaact aattatctaa
    36001 cgttttgcca ttactttcaa tcacttcttt ataccaataa aatgattttt tcttatagcg
    36061 atttatagtc aattgaaaca agaacaagac aaaagagcct cataaaaggt at
//
LOCUS       DAVLBN010000017        35305 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLBN010000017 DAVLBN010000000
VERSION     DAVLBN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.017"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..684)
                     /locus_tag="VXC24_000817"
     CDS             complement(34..684)
                     /locus_tag="VXC24_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0492960.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            796..1638
                     /locus_tag="VXC24_000818"
     CDS             796..1638
                     /locus_tag="VXC24_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0492961.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            1714..2151
                     /locus_tag="VXC24_000819"
     CDS             1714..2151
                     /locus_tag="VXC24_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0492962.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            2220..2522
                     /locus_tag="VXC24_000820"
     CDS             2220..2522
                     /locus_tag="VXC24_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492963.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(2613..3686)
                     /locus_tag="VXC24_000821"
     CDS             complement(2613..3686)
                     /locus_tag="VXC24_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0492964.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            3842..4519
                     /locus_tag="VXC24_000822"
     CDS             3842..4519
                     /locus_tag="VXC24_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0492965.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4512..5486
                     /locus_tag="VXC24_000823"
     CDS             4512..5486
                     /locus_tag="VXC24_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0492966.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VXC24_000824"
     CDS             complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VXC24_000824"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0492967.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(7536..7859)
                     /locus_tag="VXC24_000825"
     CDS             complement(7536..7859)
                     /locus_tag="VXC24_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0492968.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            8718..9347
                     /locus_tag="VXC24_000826"
     CDS             8718..9347
                     /locus_tag="VXC24_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0492969.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            9488..9757
                     /gene="rpsO"
                     /locus_tag="VXC24_000827"
     CDS             9488..9757
                     /gene="rpsO"
                     /locus_tag="VXC24_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0492970.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            10572..11186
                     /locus_tag="VXC24_000828"
     CDS             10572..11186
                     /locus_tag="VXC24_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0492971.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(11479..12228)
                     /locus_tag="VXC24_000829"
     CDS             complement(11479..12228)
                     /locus_tag="VXC24_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0492972.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            12361..14697
                     /locus_tag="VXC24_000830"
     CDS             12361..14697
                     /locus_tag="VXC24_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0492973.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            complement(15134..18280)
                     /locus_tag="VXC24_000831"
     CDS             complement(15134..18280)
                     /locus_tag="VXC24_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEV0492974.1"
                     /translation="MIRTEVTSMTVPDRLPARMRMDGRSIFQQIKNYFDTENKEYFKH
                     PNTYDGISMHLEPNILTSMEHFDLTGFHCECKDFQNQGVCKHWVAMDLYFRSLPQAIQ
                     ERIGKASHKPSFASQLIPTLPSEELQDELVEEKATAPSLALHGQVEIRNHSLAWTLKL
                     QVEQAPRAYVIKDIAHFIFLIFQKEDYFVSQKIGTIRLSLNQFNQASQNLLLYIKKYF
                     IDRNEHSYFNFSYGINPRDYGRYLETPVSYLNDLVPLFQALDVFQYVTSKAEYPLIFL
                     DDSPFIPEEEIFKVVKSNNHYEIINTAYFGFIIQEKLWIRHNHFHIIKEEHRYFLDKL
                     ATWIYHYQENSPLIFSKENKAELMQVCNIISNYVPISIPDELQIHDFIPTFAFSKTRN
                     EIALNMVWSFGEKQVHSKQDLLTLPYTYQASKARKIYHQLLSAGFKEEFHSLSKIKIV
                     DFFLKELPRFRTLGQVQLDESLEKLLVEDPAVIDIFDDESFLSVQFDFSMISEDEVEK
                     AIQALWNQESHYQTKQGKVLVFDDESLKVAQSLQDLRAKFSDGKIKMHKSRAFSLSET
                     FKDNEHVNFSRDFKKMAYDLTHPEEFDIKPYEVKAKLRSYQKEGVKWLSMLDHYHFGG
                     ILADDMGLGKTLQTITLLEANLKPDQKALILAPASLLYNWKEEFRKFVPHKQVEVAYG
                     SKTERIKQIEKSATITITSYPSFRSDLEHYQKQSYDYLILDEAQMIKNSQTKTAQALR
                     EFDVKTCYALSGTPIENRLEEIWSIFQIVLPGLLPSKKEFSKLSPQLVAKLIQPFVLR
                     RKKDEVLTELPELSEHLYSNELSSSQKTLYLAQLRRMQEMVSGASAYEIKRHKIEILA
                     GLTRLRQICNTPALFLEDYKGDSGKMDSLFELLDTIREKGSRPLIFSQFTSMLDLIEQ
                     ELEKKEMSHFKITGQTPSDKRQEMVNLFNQGEKDCFLISLKAGGTGLNLTGADTVILC
                     DLWWNPAVEMQAIGRSHRLGQTKQVDVYRLITLGTIEEKIQELQESKKELFNTVLEGQ
                     ESRSNLSVDDIKEILGVE"
     gene            complement(18469..19707)
                     /locus_tag="VXC24_000832"
     CDS             complement(18469..19707)
                     /locus_tag="VXC24_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492975.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(19709..21145)
                     /locus_tag="VXC24_000833"
     CDS             complement(19709..21145)
                     /locus_tag="VXC24_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV0492976.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLENYEAANFLHGYSLLFGKAGFLFG
                     ILDRYEKTKERYLIDISKRLVDHLMRVYDNISNLDFALGKSGILLSLMKYCTIFDDKK
                     LANFIKNNINDAYSLLESEDNGDIYSNNFAHGRSGAAYVLKAYTDIFGDSRYQNHLQK
                     FSDGISELLEEKLSSFSKLDNLGLSWCDGVSGLILYLCLIDKERYSEIIYKSQLEMVQ
                     QYEAMGTSFCHGLSSLLQTTIYNKNQKVEQFIKKILLTRSYRNNDRLLQFQGEDGINS
                     YFDFGVGNLGIYWTLLGYTFPFELSKGD"
     gene            complement(21219..21749)
                     /locus_tag="VXC24_000834"
     CDS             complement(21219..21749)
                     /locus_tag="VXC24_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0492977.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(21743..22211)
                     /locus_tag="VXC24_000835"
                     /pseudo
     CDS             complement(21743..22211)
                     /locus_tag="VXC24_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22760..23437
                     /locus_tag="VXC24_000836"
     CDS             22760..23437
                     /locus_tag="VXC24_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0492978.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23424..24221
                     /locus_tag="VXC24_000837"
     CDS             23424..24221
                     /locus_tag="VXC24_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0492979.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24238..25341
                     /locus_tag="VXC24_000838"
     CDS             24238..25341
                     /locus_tag="VXC24_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0492980.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25642..26661
                     /gene="galE"
                     /locus_tag="VXC24_000839"
     CDS             25642..26661
                     /gene="galE"
                     /locus_tag="VXC24_000839"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0492981.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26663..27598
                     /locus_tag="VXC24_000840"
     CDS             26663..27598
                     /locus_tag="VXC24_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0492982.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTNWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSYHRS"
     gene            27773..28417
                     /locus_tag="VXC24_000841"
     CDS             27773..28417
                     /locus_tag="VXC24_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492983.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            28456..28557
                     /locus_tag="VXC24_000842"
                     /pseudo
     CDS             28456..28557
                     /locus_tag="VXC24_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(28608..28814)
                     /locus_tag="VXC24_000843"
     CDS             complement(28608..28814)
                     /locus_tag="VXC24_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0492984.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            28866..29342
                     /locus_tag="VXC24_000844"
     CDS             28866..29342
                     /locus_tag="VXC24_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0492985.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            29351..30022
                     /locus_tag="VXC24_000845"
     CDS             29351..30022
                     /locus_tag="VXC24_000845"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0492986.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30153..30491
                     /locus_tag="VXC24_000846"
     CDS             30153..30491
                     /locus_tag="VXC24_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0492987.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            30494..31123
                     /locus_tag="VXC24_000847"
     CDS             30494..31123
                     /locus_tag="VXC24_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0492988.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            31363..32514
                     /locus_tag="VXC24_000848"
     CDS             31363..32514
                     /locus_tag="VXC24_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0492989.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32827..33576
                     /gene="truA"
                     /locus_tag="VXC24_000849"
     CDS             32827..33576
                     /gene="truA"
                     /locus_tag="VXC24_000849"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0492990.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            33566..34339
                     /locus_tag="VXC24_000850"
     CDS             33566..34339
                     /locus_tag="VXC24_000850"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0492991.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34317..34778
                     /locus_tag="VXC24_000851"
     CDS             34317..34778
                     /locus_tag="VXC24_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0492992.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35005..>35305
                     /locus_tag="VXC24_000852"
     CDS             35005..>35305
                     /locus_tag="VXC24_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0492993.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKVLHEGWTKDRVSLEYGLPSRTILLNWLAQYR"
BASE COUNT        10350 a         6402 c         7629 g        10924 t
ORIGIN      
        1 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
       61 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
      121 gctgaagcca tcaaactgct taacttggag ctggtcaccg atgtgaagtg agtgcttgtc
      181 cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg cgccagcttc
      241 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
      301 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
      361 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
      421 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
      481 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
      541 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
      601 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
      661 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
      721 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
      781 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
      841 gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata ctggcttttg
      901 ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt ggatcaacta
      961 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     1021 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     1081 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     1141 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
     1201 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     1261 gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac tggtgggcaa
     1321 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     1381 gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt agatatggac
     1441 ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
     1501 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     1561 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
     1621 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     1681 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
     1741 gcaactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
     1801 tttctggctg ctagtgttgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
     1861 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
     1921 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
     1981 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
     2041 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
     2101 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
     2161 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
     2221 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
     2281 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
     2341 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttgcctttg
     2401 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
     2461 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
     2521 gactattaga ttctatttaa aaagacttag aatgaacatg aaagtatgta ttctaggtct
     2581 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
     2641 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
     2701 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
     2761 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
     2821 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
     2881 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
     2941 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
     3001 agcatcatac cgataatgga accttgtgga atgaatatct tgcttctatc cattatcctt
     3061 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
     3121 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
     3181 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
     3241 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
     3301 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
     3361 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
     3421 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
     3481 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
     3541 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
     3601 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
     3661 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
     3721 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
     3781 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
     3841 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
     3901 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
     3961 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
     4021 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
     4081 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
     4141 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
     4201 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
     4261 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
     4321 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
     4381 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
     4441 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
     4501 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
     4561 gtctttttat ctatctgctt tctttggcat ttcttgtctt actctttcag tttttatttg
     4621 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatattat
     4681 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
     4741 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
     4801 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
     4861 ataccttgtg ggtccatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
     4921 aagtggtcga ccgccaactg aagcagcaac tagaacagga aattttcaaa atcgactcct
     4981 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
     5041 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
     5101 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
     5161 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
     5221 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
     5281 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
     5341 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
     5401 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
     5461 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
     5521 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
     5581 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
     5641 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
     5701 tgtgaagcac gaatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
     5761 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt ccacgtgttt ttcgttagat
     5821 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
     5881 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
     5941 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
     6001 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
     6061 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
     6121 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
     6181 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
     6241 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
     6301 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
     6361 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
     6421 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
     6481 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
     6541 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
     6601 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
     6661 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
     6721 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
     6781 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
     6841 atagcgttgt cgctgtttcc acgccagtac gcaccagcta catggagaag gtggaagatt
     6901 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
     6961 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
     7021 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
     7081 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
     7141 atttgaccag ctgtgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
     7201 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
     7261 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
     7321 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
     7381 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
     7441 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
     7501 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
     7561 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
     7621 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
     7681 gtttcatcat agtagcgtcc ttgctttgtc atcaccagtc gttggaaatt tccaatatca
     7741 ttagataaag ccaagaggtc ttcttctacc gtccacttga aatcatgatg cttaacttcc
     7801 agttcgtgat aagcttgtcg gattgcccaa ctgcgctcca ctaattcttg caactccata
     7861 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
     7921 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
     7981 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
     8041 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
     8101 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcatat tttgtagaat
     8161 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
     8221 gtaaattagt ataaactcac caaaggttat gatagtaaag taaaagagca gtccgttacc
     8281 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
     8341 taccagaggt gtaaagaaga gaagattgtt tatatagtgt aaaggggtca gaaacaacta
     8401 gcaagaacaa ctcataaagt ggccaataaa agaataatat gaccagatag taggggagat
     8461 gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa cttagatctc
     8521 ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac aaagaagatt
     8581 tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat aataattaag
     8641 caagactatt gatattgatt attaagagtg tcacatttgt tgtaactaaa ataattacaa
     8701 caatagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa gcggggaaag
     8761 caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt cgttctgaaa
     8821 acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca aaagatgatc
     8881 ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat acgctaccgc
     8941 tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag acacgttttc
     9001 tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca cgacttttag
     9061 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaatttg
     9121 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
     9181 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
     9241 gaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
     9301 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
     9361 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
     9421 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
     9481 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
     9541 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
     9601 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
     9661 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
     9721 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa ggccgtcaaa
     9781 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
     9841 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataataa agctactcta
     9901 aattgggtag ctttgttgcg ttgtcacctt acctcgctat actcaagtat aatcttcggt
     9961 tacggttcct agcactgtaa ggtaaaataa actagctttt ctcccttcgt ggagattttt
    10021 ttgtttcact gaaagtttcg tacgatcttc acctcgtccc ctagtctata aacgatttat
    10081 ctagcaagaa tcatgatgct aagggtgtca aaaatccgta tgaaaatagg gaaatgacac
    10141 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctaaaa
    10201 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
    10261 ctacaaaaat ctcaaatggt atcagctaat tacaccataa aggtgcgcag ctactcggct
    10321 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
    10381 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
    10441 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
    10501 gctaaattaa tgtgtttgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
    10561 aggttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    10621 tcgattattt aattatttta attattttat ttgcacagct atcacagaat aaacagaaat
    10681 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    10741 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    10801 ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa gaagaggaag
    10861 aaattattca aagattagaa caaagcaagg caaatcaact gttttggaca gttacattgc
    10921 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    10981 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    11041 agattagtag ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    11101 gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat gaaaatggca
    11161 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcctgagct
    11221 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    11281 gttactctat tgtagagtgg cttttgattt gattagggga ttcttataaa tatagtaaaa
    11341 tgaaataaga ataggacaaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    11401 gaagtagagg tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt
    11461 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    11521 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    11581 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    11641 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    11701 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    11761 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    11821 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    11881 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    11941 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    12001 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    12061 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    12121 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    12181 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    12241 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    12301 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    12361 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    12421 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    12481 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    12541 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    12601 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    12661 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    12721 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    12781 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    12841 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    12901 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    12961 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    13021 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    13081 tcatctgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    13141 ttgaccatta cttcgctctt gactgcagtg attaagctag gtttgaaaaa ggtcttggtg
    13201 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    13261 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    13321 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    13381 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    13441 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    13501 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    13561 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    13621 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt
    13681 cgagagggag cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt
    13741 atctctggtg acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac
    13801 tatcacagct atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag
    13861 gagacagcta ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg
    13921 aaaaaagcgg gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt
    13981 cgtgaggcgg attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc
    14041 aatctggttc tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt
    14101 cgcgtggtca ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc
    14161 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    14221 atttttccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    14281 ccattcgttc tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga
    14341 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa
    14401 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    14461 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    14521 gtcctattga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatt
    14581 caaaaactgc ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg
    14641 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    14701 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    14761 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    14821 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtctgat gcaagaaata
    14881 attctcttcg aaaatatctt caaaccaggt ccgttctatc cacaatctca aagcggtact
    14941 ttgagcaact tgtggtcagc tccctagttt gatagtataa aaactgtcag ataaaggggt
    15001 ggcgaaattg tatctaaacg aacagaaacg tgatggtaag gcgtatagag ctcataggat
    15061 ggcaaggaaa gtctagaacc taaaaaagaa ctagataaat ccactaagtg tggttactct
    15121 agttcttttt cgtttattca acacccaaga tttctttaat atcatcaacg ctcagattgc
    15181 ttctgctttc ttgtccttca aggacggtgt tgaagagttc ctttttactt tcttggagtt
    15241 cttgtatttt ttcctctatg gtaccaagtg tgataaggcg atagacatcg acttgtttgg
    15301 tctggccaag gcggtggctt cggccgatgg cttgcatctc aactgctgga ttccaccaga
    15361 ggtcacagag gatgacggta tcagctcctg ttagattcag tcctgttcca cctgctttta
    15421 gggaaatgag gaagcagtct ttttcccctt gattgaaaag attgaccatt tcttgacgtt
    15481 tatctgaagg tgtttgtcct gttattttaa agtgagacat ttcttttttc tctagttctt
    15541 gctcaatgag atcaagcata gaggtgaatt gtgaaaagat aagtggtcgt gacccttttt
    15601 cacgaatggt gtctaggagc tcgaataagc tgtccatttt tccactatcc cctttgtagt
    15661 cttctaaaaa gagagcaggg gtattacaga tttgtctaag tcgggtcagt cctgctaaga
    15721 tttcaatttt atgacgttta atctcatagg cgctggctcc tgaaaccatt tcttgcatgc
    15781 gtcgaagttg agctagatag agcgtttttt gcgaactgct gagttcattg ctgtagaggt
    15841 gctcgctcag ttcaggcaat tctgtcagaa cttcgtcttt tttcctacgc agaacaaaag
    15901 gttgaatcag tttagcaacg agttgaggtg acaattttga aaattccttt ttacttggta
    15961 ggagacctgg taatactatc tggaaaatag accaaatctc ttcgagacgg ttttcaatag
    16021 gagttccaga tagggcatag caggttttga catcaaattc tcttaaagct tgtgctgttt
    16081 tggtctgact attttttatc atctgtgctt catctaggat gaggtagtcg taagactgct
    16141 tttgataatg ttcaaggtca gatcgaaaag atggatagct tgtaatagtg atagtagcag
    16201 atttttcaat ttgtttgata cgctcagttt tgctaccata ggctacttca acctgtttgt
    16261 gaggcacaaa ttttcggaat tcttccttcc aattataaag aaggctggct ggagctagga
    16321 taagagcttt ctggtctggt ttaaggttgg cttccagaag agtgatggtt tgcaaggttt
    16381 tccctagacc catgtcgtct gccaggattc ccccaaaatg ataatgatcc agcatactca
    16441 gccacttgac tccttctttt tgataggagc ggagtttggc cttgacttca taaggcttga
    16501 tatcaaattc ttcagggtgg gtcaggtcat aagccatctt tttgaaatca cgagaaaaat
    16561 tgacatgttc attgtctttg aaggtttcag aaaggctaaa ggcacgagat ttgtgcatct
    16621 tgatttttcc gtctgaaaat ttagcgcgaa gatcttggag actttgagca accttgagac
    16681 tttcatcgtc aaagactaga acctttcctt gcttggtttg gtagtggctt tcttgattcc
    16741 ataaagcttg gatagctttt tcaacctcat cttctgaaat catagaaaaa tcaaactgaa
    16801 ctgaaaggaa gctttcgtcg tcaaaaatgt caatgacagc aggatcttct actaagagtt
    16861 tttcaagcga ttcatctagt tgaacttgac ccagagtacg aaaacggggg agttctttta
    16921 ggaagaaatc aacgattttg attttggaaa gactatgaaa ttcctctttg aaaccagcag
    16981 aaagcagttg atgatagatt tttctagctt tgctagcttg gtaagtatag gggagggtta
    17041 ggagatcttg tttagaatgg acttgttttt ctccaaagga ccacaccata ttaagggcaa
    17101 tttcatttct agtcttggag aaggcaaagg tggggataaa gtcatggatt tgtaattcat
    17161 ctgggatact gataggaaca tagtttgaga tgatattaca gacttgcatg agttcagcct
    17221 tattttcttt tgaaaagata agaggagaat tttcttgata atgatagatc caagtagcta
    17281 atttatccaa aaagtaacgg tgttcttctt tgatgatgtg gaagtgattg tgtcgaatcc
    17341 aaagtttttc ttgaataatg aaaccaaaat aagctgtatt gatgatttca taatggttat
    17401 tagatttgac aactttaaaa atttcctctt ccgggataaa gggactatca tctaagaata
    17461 taagagggta ttcggctttt gaggttacat attggaagac atccaaagct tgaaaaagtg
    17521 ggacgaggtc gtttaaatag ctaacaggag tctctaaata gcgtccgtaa tctctagggt
    17581 taatgccata actgaagttg aaataagaat gttcatttct atcgataaaa tattttttaa
    17641 tatagaggag taggttttgg gatgcttgat taaactgatt caaggataat ctgattgtcc
    17701 cgattttctg tgaaacaaag taatcttcct tttggaaaat gagaaaaatg aagtgagcta
    17761 tatccttgat aacataggca cgaggagctt gttctacctg taattttaag gtccaggcta
    17821 ggctatgatt tcggatttcg acttgtccat gaagggcaag tgaaggcgcc gtagcttttt
    17881 cttctaccag ttcatcttgg agctcttcag atggcaaggt aggaatcagt tggctggcaa
    17941 aacttggttt atgactcgct ttaccaatgc gttcttgaat agcttggggg agactacgaa
    18001 aataaagatc catggcaacc cagtgtttac agactccctg attttggaaa tccttacatt
    18061 cgcaatgaaa gccagtcaaa tcgaagtgct ccatactggt caggatgttg ggctccagat
    18121 gcatggaaat accatcatag gtattggggt gcttaaaata ttccttattt tcagtatcaa
    18181 aatagttttt tatctgttgg aaaatagagc ggccatccat tctcatacga gcaggtagtc
    18241 tatcgggaac cgtcattgaa gtaacctctg ttctaatcat tcttttctct atcttatcag
    18301 aatttatagg aaaagaatag atttatctta cataaattgc atcttgatag ggattggaaa
    18361 catttgtagt tgcaagatag ttgtatgtaa tatcgacaat caattacaag gagattacga
    18421 ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct aaacttcttc
    18481 ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta gtaaaattat
    18541 aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga gagcaaggga
    18601 taggacagct gggataagta agttgataac attgatggat gattgaactg atcccattaa
    18661 ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata ctcctgccga
    18721 gaaagcatca cccgcacttc ctagtaaaat aagtaaaaaa cttccacgta gaaaatctat
    18781 aacaatgaga gactccatca atagactcca ataaatattc aggcgaatag aaattttttt
    18841 agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta tcattattaa
    18901 aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca gtagaatcgc
    18961 actgacaggc tctaccatca tcaaaacagc ttgactaatg gacaaaatcc aaagcaagac
    19021 catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct ggaaaaagct
    19081 actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca agcggtttcg
    19141 gataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa aagctagagt
    19201 agaaatgcta aacagtccta aaaatactcc tccgctgaga ttacctatca aacgtacaat
    19261 ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta ttagtcgtat
    19321 gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa tcaagttcat
    19381 gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga gcaaagtcac
    19441 tccagaataa aggaggacct tgataaagag gatagaaata tacttgctga ttcgattttt
    19501 ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatgg tttctgatag
    19561 gctaatcaaa aatatagcta agggagcaaa ggcataagaa gagacataat tgataaaagc
    19621 taagtaaaaa atagtatctc caaaacttga aatccactca tttactgtta gctgacgaaa
    19681 agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca aatgggaatg
    19741 tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca aaataactgt
    19801 ttattccatc ttccccttga aattgtaata atctatcatt attacgataa gaacgagtca
    19861 ataagatttt ttttatgaac tgttcaacct tttgattttt attgtatatt gttgtttgca
    19921 ataaactact taaaccatgg caaaaactag ttcccattgc ttcatattgt tgcaccattt
    19981 caagttgtga tttatagatt atctcagagt atctttcttt atcaatcaaa caaagataca
    20041 atattaatcc tgaaactccg tcacaccaag aaagacctaa attatctaat ttagaaaagc
    20101 ttgaaagttt ctcttctagt aattcagata tcccgtcaga aaatttttgt aaatgatttt
    20161 gatagcgact atctccaaaa atatcagtat aggcttttaa tacataggca gcacctgaac
    20221 gtccgtgagc aaaattatta gaatatatat ctccattatc ctcggattct aataaactat
    20281 atgcatcatt tatattgttc ttgataaaat ttgctagttt tttatcatca aaaatggtac
    20341 aatatttcat caaactgagt aggataccag acttccctaa agcaaaatct aagttactaa
    20401 tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct attaaatatc
    20461 tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct ttcccaaata
    20521 gtagagagta accatgtaaa aaattagctg cttcataatt ttctaatttc gtaagccatt
    20581 ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat aaaactcctc
    20641 caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt gacggaaaca
    20701 aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc tcagcctcct
    20761 ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa agaatgtcac
    20821 ttgtaacttg tttcaattgc tttatttttt ggattttttc tccctggctc atcattaata
    20881 aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta gctattttta
    20941 ttagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct tttgaaaagg
    21001 ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa taatcttgtt
    21061 gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt ttaactcgtc
    21121 ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata tcaccttttt
    21181 tggtatatat aaaatttgta ggagctatat ctacaatttt atattcccag tttatggatg
    21241 taacttacta tattcacaat gttatccagt gttttttctc taatatttaa ggagtgttct
    21301 gtttctcgaa taaattcttc aaagtttaac ccgtcaactt gttcctgaac aagaaaataa
    21361 tcatccacga tataaaattc atcagttaaa ttagtagtat aacttttatc ggctaatttt
    21421 tttagcatgt gagcttcatt ttttatatca tcaagagctg tccattctcc ttcagcatca
    21481 taattcacaa aaggtcttga ctgcttgatg attacttttt gcccgtccga ttttctaatt
    21541 gcccgataaa catttccttt atttgatctc ttaataattt tttccatttt gtatttattt
    21601 attgcagagt ccttacttga aacttcacat gtggtttgaa aataaatcct tttttcttct
    21661 tctgaaaata aatccatttt ccagctagga agactaggga aattttgtct cttatcttct
    21721 acatagttct tccttttttc atctagcaat aaatagatga cttttttatt tttttcatca
    21781 taagcttgtt tttttaaaaa agccccatat ctataatgaa ctggagaatg cattccacat
    21841 tgatagtcag atagtatttt tggagcctta aattctgaca gtctattcgt aagattacaa
    21901 atcatactct tagcttcaga ttctgactta ggatatagag ttataaattt gttagcagta
    21961 gggctcattt ccctagggga attaattttt tttaattcct ctaaattttt aacaacttta
    22021 aagctacaat tatttagttg ggatagttta tacacaatct taaaaatatt tacagcgtct
    22081 tttatttggg agcttatgtg tattttccac ccttgtgcag gcatcttatc tgataaataa
    22141 tagtaattcc aaatatcacc ctgttggaaa tttttatcac attttaaaca ttctttctct
    22201 aataaatcca taacaaactc ctaattatta aaataggcta gagacacagc actagcctat
    22261 tccgtaagta aagctactta ttttatataa aatataacta gcgacctgta attaaacaag
    22321 taaaagaaca atacttaggg agacctgtga caatgatatc ttcctctgga agtagttcta
    22381 attcaaacaa tgtttgttcc atgactgtat cctcctgtta tgataaattc cagaaagcat
    22441 agagcaaatt cgtggttcgt ctgactaaat ttcttatctg aacaccacct tcaaatacaa
    22501 attttagtca aacttttatt ttttctaact ttctaattat attctaccat gtgtttttat
    22561 atgtcaagaa ttttctgaat aaactgttta ttttttattt tttgacattt ttgcaaattg
    22621 tttaaaatct ttcaattgga ttcacttatt actttaggac attgaaactt ctttcgccag
    22681 aggtgcttat attactggga agttgaagat tgaaatgtgg tataataaga ggtaatagag
    22741 ttttggaaag tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc
    22801 acagggggct attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt
    22861 tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc
    22921 tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa
    22981 tggcttggca gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg
    23041 tggtcgtttg attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg
    23101 tttgatcctc cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg
    23161 attccagatt gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt
    23221 ggtggaagca ggacaaatga agctatcagc cagtgatgtt cgctttggac cgttcttgtg
    23281 caaagaggtc agtccagtct ttgtccaaaa atggcaaaaa gaagctgtta agctagagtt
    23341 tgccctcgga caaatcccag acaaaaatct ggaagaacgt caagttctag tagataagat
    23401 tcaagccatc aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct
    23461 tttgccctca ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag
    23521 acaagggtat ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg
    23581 ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca
    23641 aggacttgct tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgaca
    23701 tcgcagttta tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt
    23761 tttgtcagat gctagaaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg
    23821 gaattggacg tattgggaat attcagcctc agacctttgg agaattggcc caacatgtca
    23881 agcaagtctt tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga
    23941 agcctatttc aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt
    24001 tggcaaaggg ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata
    24061 tgctgtctga tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg
    24121 aaaaaatcgc agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt
    24181 tacctagtca agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg
    24241 aaaaaagttg ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg
    24301 agagaaagtg acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc
    24361 gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg
    24421 gcgcgcttgg gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa
    24481 gaaatcgact tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg
    24541 gaagaacttt atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta
    24601 gccattctga accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc
    24661 ctgctctatg cttctggtgg agcgagagta gatggccaac tcttggtaac tcgtctgcta
    24721 gaagccagtc atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc
    24781 taccagattg gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg
    24841 gacatgttag aacccttggg ttatgaagta gatgttcgtc ctcaaaaagg acaactacga
    24901 gattatcagc tggtccaaga tatggaagct taccctgttg tcatgccaga aggggagtgg
    24961 gatttgattc cttttgcagg tgggaaattg tccttaggcg ctacccacga aaatgacatg
    25021 ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact
    25081 cactatctga ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac
    25141 accagtgatt tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc
    25201 agtggattag gttcatcagg cctcacaact ggtcctatta ttggttacca tttagctcaa
    25261 ctgatccaag acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc
    25321 aaacgagtaa aaagcgaata atactcaatg aaaatcaaag aacaaactag gtaactagcc
    25381 gcgggttact caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa
    25441 cactgttttg aggttgtaga tagaactgac gaagtcagta accataccca tggcaaggcg
    25501 acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc
    25561 aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa
    25621 tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt
    25681 attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat
    25741 aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaattac aggagttgag
    25801 attcctttct atgaggcaga tattcgtgac acagctaccc tcagagatat tttcaagcag
    25861 gaagaaccga ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt
    25921 atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg
    25981 gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg
    26041 cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtacc
    26101 aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt
    26161 gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat
    26221 ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta
    26281 gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac
    26341 tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa
    26401 ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt
    26461 atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgtatcgt agaacgtcgc
    26521 ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg
    26581 gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat
    26641 ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga
    26701 ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga
    26761 aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc
    26821 ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga
    26881 agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc
    26941 agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt
    27001 agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag
    27061 tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc
    27121 gggtgtccgt gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac
    27181 cgagtccaat cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt
    27241 ggactatcca aatgtcgaaa ggcaggctgg caagacaaat tggagtttta ggcaactctt
    27301 tttctactcc attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt
    27361 agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac
    27421 cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct
    27481 tggaggtatt caactcttga ccattgggat tctcggcaag tatatcagta agatttattt
    27541 agaaaccaaa aaaagaccgc tttatcttat caaagaaaaa agttatcata gatcatgaaa
    27601 aagtaggagt tatctagcgc agtcactttt ttgtaattat aattcttttg gtctggaact
    27661 tgagtgattt ttaaaaaaat tagggatttg acatgatata aatgaactat gtggaataaa
    27721 tttactgcaa agacgataac ttaataaata aaaaattcag gagggttatt ttatgctaag
    27781 taaagaggag tatattgaag aaatcgggct tatagagaaa caaaattatg tagaggttga
    27841 actgtatcct ttagttgctg atataattaa tccgacttta aaaaatagtt tatcaaaaag
    27901 atatgtcttc ggaagaagaa agagtaatat ggggcaaata tattatggtc taagtaattt
    27961 tcctgatata gttattttgg ataagaatta tcaaaataaa gccagaaaaa gtatagaaat
    28021 tgaagaatgg aagaaacttc gaggatgcgt ggaaattaag agtttaaagc atgatttaat
    28081 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    28141 gggacaactt attggagacc ttttatggta taaaaaagta atttatacaa atggaattga
    28201 atggagattt ctaagtttag atgacaagga agagatagat aatacaattg ttcaagtagt
    28261 taacaaaaga atagaaacag aagaagcggg aaattctttt gattggtgga agaatattaa
    28321 agatttatcg ttcaattata cggatatata tttatctaaa gattgtatac aagagtggga
    28381 tgaatttgta aagaaagtaa aggaaataga atggtaggag tctattctca ttgagaaatt
    28441 tagattataa gtcgcagtaa gatttattta gagactaaaa aaagaccact ttatcttatc
    28501 aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag actataattt
    28561 tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta ggcttcctgg
    28621 tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc ctgactagga
    28681 gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg
    28741 taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg ttcaggtata
    28801 agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa aacaaggagt
    28861 aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa tcaagagcag
    28921 agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt ttgacgatcc
    28981 tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc tatctatcat
    29041 cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat gcaagtgtag
    29101 tacaaatctc atcttcaagc agttctcagc ctgagcagag ttcagagcca gaatctactt
    29161 ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc gcaggagaag
    29221 gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag gccttgaatc
    29281 ctgggcacat ggttacagga tcttggtttg ctaatccagg tgatgttata aaaataaaat
    29341 aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca gcggtaagag
    29401 tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata caggagctat
    29461 gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag aagtcgaagc
    29521 ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa ctggagacca
    29581 gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg aagtgaccaa
    29641 tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt ctctccaaca
    29701 agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa ctgttgtatt
    29761 gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag cagagcgtcg
    29821 ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa aaaaggaaat
    29881 tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac aagcagagga
    29941 tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc
    30001 agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg gtttttttct
    30061 aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa ttttgatttt
    30121 caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat
    30181 gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag tgtgctcatg
    30241 agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc gatgccaacg
    30301 gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg
    30361 cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgacc
    30421 acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca gagtttgtga
    30481 ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta tcttcttgtt
    30541 tctagcggct tttacgggag tttatcttga aattactaag catggtggtt ttgggatgct
    30601 tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt atcttctaaa
    30661 ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct taaaaggtgg
    30721 ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg cgcccattgc
    30781 gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca tctggttttt
    30841 agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc cagcagtgtg
    30901 gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg ttctaaaact
    30961 caatattcca aatgctaagg ataatccttt cccttacttc tttttgaatg tgaacaaggg
    31021 ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg tagcaggatt
    31081 tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt cgaaaatctc
    31141 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgaaca acctgcggct
    31201 agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat tcattttcga
    31261 atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat ttgataacta
    31321 tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    31381 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    31441 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    31501 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    31561 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31621 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31681 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31741 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31801 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31861 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31921 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31981 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    32041 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    32101 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    32161 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    32221 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    32281 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    32341 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccatttgtt
    32401 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    32461 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    32521 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    32581 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt ctaatagagt
    32641 tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32701 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag tatgagattt
    32761 ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct tgataaaata
    32821 gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt tgctggcttt
    32881 cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt gaccagatta
    32941 aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg ggttcatgcc
    33001 ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa actccgtttt
    33061 gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct tgtggcagat
    33121 gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt ggatagagga
    33181 cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc actcgatgtg
    33241 gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac cggttttaca
    33301 gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag tttaatagtc
    33361 gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt gtataaacag
    33421 attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc agtagagcag
    33481 attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc agcaccaaat
    33541 ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac tttctggaaa
    33601 tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct tgaacggctt
    33661 gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat ttgaagtctt
    33721 tccaactgat gataccattt ttcaacatga attagatagc ttgcgtgatg tggaatttgg
    33781 gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct tggactttat
    33841 caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca aggaaacgca
    33901 tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt atgtcagtgt
    33961 gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta aaaccttgga
    34021 agacatgaaa actgcagcgc agaaattgca tgatttagga gctccagcag tcattatcaa
    34081 gggaggcaat cgtcttagtc aggacaaggc ggtggatgtc ttttatgatg gacagacctt
    34141 tactatccta gaaaatccag ttatccaagg ccaaaatgct ggtgcaggtt gtacctttgc
    34201 ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag tagaaagctc
    34261 taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa gacaatatga
    34321 agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt tctgtggttc
    34381 taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta gatgctggtg
    34441 tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga ggactagcaa
    34501 gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc ttggtcaacc
    34561 atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta ggccttattt
    34621 tagcaattat tgccatggta ggaggctacg ccttgggttc tactttgatg aatggctggg
    34681 cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa tatggtaggg atgattgtag
    34741 gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa atctcttcaa
    34801 accacgtcag cttccatctg caacctcaaa ccactgtttt gagcagcctg aggctagctt
    34861 tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag tatttcaaat
    34921 aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta gacagaaaaa
    34981 atctaacttt tggggtgttt tattatgaaa ctaacttatg atgataaagt tcagatctat
    35041 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
    35101 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    35161 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgattaataa agtcttacat
    35221 gaaggctgga ctaaagatag agtttctctt gaatacggtc tcccaagtcg tacgatactt
    35281 cttaactggc tagcacaata cagga
//
LOCUS       DAVLBN010000018        35084 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLBN010000018 DAVLBN010000000
VERSION     DAVLBN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.018"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(224..586)
                     /locus_tag="VXC24_000853"
     CDS             complement(224..586)
                     /locus_tag="VXC24_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0492994.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            600..746
                     /locus_tag="VXC24_000854"
     CDS             600..746
                     /locus_tag="VXC24_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0492995.1"
                     /translation="MKTKEQTRKLASGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FEEY"
     gene            complement(877..1014)
                     /locus_tag="VXC24_000855"
                     /pseudo
     CDS             complement(877..1014)
                     /locus_tag="VXC24_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1392..2081)
                     /gene="rplA"
                     /locus_tag="VXC24_000856"
     CDS             complement(1392..2081)
                     /gene="rplA"
                     /locus_tag="VXC24_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0492996.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVTLAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2289..2714)
                     /gene="rplK"
                     /locus_tag="VXC24_000857"
     CDS             complement(2289..2714)
                     /gene="rplK"
                     /locus_tag="VXC24_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0492997.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2837..3553)
                     /locus_tag="VXC24_000858"
     CDS             complement(2837..3553)
                     /locus_tag="VXC24_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0492998.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3571..4032)
                     /locus_tag="VXC24_000859"
     CDS             complement(3571..4032)
                     /locus_tag="VXC24_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0492999.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(4034..5071)
                     /locus_tag="VXC24_000860"
     CDS             complement(4034..5071)
                     /locus_tag="VXC24_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0493000.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5169..6494)
                     /gene="brnQ"
                     /locus_tag="VXC24_000861"
     CDS             complement(5169..6494)
                     /gene="brnQ"
                     /locus_tag="VXC24_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0493001.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6665..6757)
                     /locus_tag="VXC24_000862"
     CDS             complement(6665..6757)
                     /locus_tag="VXC24_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0493002.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6800..6952)
                     /locus_tag="VXC24_000863"
     CDS             complement(6800..6952)
                     /locus_tag="VXC24_000863"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0493003.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7081..7158)
                     /locus_tag="VXC24_000864"
                     /pseudo
     CDS             complement(7081..7158)
                     /locus_tag="VXC24_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7159..7737)
                     /locus_tag="VXC24_000865"
     CDS             complement(7159..7737)
                     /locus_tag="VXC24_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0493004.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VXC24_000866"
     CDS             complement(7791..9191)
                     /gene="pepV"
                     /locus_tag="VXC24_000866"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0493005.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTVP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKIRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9204..9809)
                     /locus_tag="VXC24_000867"
     CDS             complement(9204..9809)
                     /locus_tag="VXC24_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0493006.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9980..10780
                     /locus_tag="VXC24_000868"
     CDS             9980..10780
                     /locus_tag="VXC24_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0493007.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINHWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10958..11791)
                     /locus_tag="VXC24_000869"
     CDS             complement(10958..11791)
                     /locus_tag="VXC24_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0493008.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11781..13625)
                     /gene="uvrC"
                     /locus_tag="VXC24_000870"
     CDS             complement(11781..13625)
                     /gene="uvrC"
                     /locus_tag="VXC24_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0493009.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13664..14365)
                     /locus_tag="VXC24_000871"
     CDS             complement(13664..14365)
                     /locus_tag="VXC24_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0493010.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(14444..15676)
                     /gene="murN"
                     /locus_tag="VXC24_000872"
     CDS             complement(14444..15676)
                     /gene="murN"
                     /locus_tag="VXC24_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0493011.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15681..16901)
                     /gene="murM"
                     /locus_tag="VXC24_000873"
     CDS             complement(15681..16901)
                     /gene="murM"
                     /locus_tag="VXC24_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0493012.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17013..17792)
                     /locus_tag="VXC24_000874"
     CDS             complement(17013..17792)
                     /locus_tag="VXC24_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0493013.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWFKRTNVERLLRATNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17869..19530)
                     /locus_tag="VXC24_000875"
     CDS             complement(17869..19530)
                     /locus_tag="VXC24_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0493014.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19705..21927)
                     /gene="recJ"
                     /locus_tag="VXC24_000876"
     CDS             complement(19705..21927)
                     /gene="recJ"
                     /locus_tag="VXC24_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0493015.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISR
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNTVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22302..22961
                     /locus_tag="VXC24_000877"
     CDS             22302..22961
                     /locus_tag="VXC24_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0493016.1"
                     /translation="MLGPSGSGKSTLIRTINGLEAVDKGSLLVNGHQVAGASQKDLVP
                     LRKEVGMVFQHFNLYPHKTVLENVTLAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDS
                     YPAMLSGGQKQRIAIARGLAMHPELLLFDEPTSALDPETIGDVLAVMQKLAHDGMNMI
                     IVTHEMGFAREVADRIIFMADGEVLVDTTDVDNFFDNPSKPRAQQFLSKIINHESDKV
                     K"
     gene            23001..23765
                     /locus_tag="VXC24_000878"
     CDS             23001..23765
                     /locus_tag="VXC24_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0493017.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23778..24455
                     /locus_tag="VXC24_000879"
     CDS             23778..24455
                     /locus_tag="VXC24_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0493018.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24465..25124
                     /locus_tag="VXC24_000880"
     CDS             24465..25124
                     /locus_tag="VXC24_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0493019.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25419..26609
                     /locus_tag="VXC24_000881"
     CDS             25419..26609
                     /locus_tag="VXC24_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0493020.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITYLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26930..27811)
                     /locus_tag="VXC24_000882"
     CDS             complement(26930..27811)
                     /locus_tag="VXC24_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0493021.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27952..29280)
                     /gene="vncS"
                     /locus_tag="VXC24_000883"
     CDS             complement(27952..29280)
                     /gene="vncS"
                     /locus_tag="VXC24_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0493022.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29277..29933)
                     /gene="vncR"
                     /locus_tag="VXC24_000884"
     CDS             complement(29277..29933)
                     /gene="vncR"
                     /locus_tag="VXC24_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0493023.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29982..30065)
                     /gene="pep27"
                     /locus_tag="VXC24_000885"
     CDS             complement(29982..30065)
                     /gene="pep27"
                     /locus_tag="VXC24_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0493024.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30245..31624)
                     /gene="vex3"
                     /locus_tag="VXC24_000886"
     CDS             complement(30245..31624)
                     /gene="vex3"
                     /locus_tag="VXC24_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0493025.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31676..32323)
                     /gene="vex2"
                     /locus_tag="VXC24_000887"
     CDS             complement(31676..32323)
                     /gene="vex2"
                     /locus_tag="VXC24_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0493026.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32336..33613)
                     /locus_tag="VXC24_000888"
     CDS             complement(32336..33613)
                     /locus_tag="VXC24_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493027.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33969..34139)
                     /locus_tag="VXC24_000889"
                     /pseudo
     CDS             complement(33969..34139)
                     /locus_tag="VXC24_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34282..34881)
                     /locus_tag="VXC24_000890"
     CDS             complement(34282..34881)
                     /locus_tag="VXC24_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493028.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNIK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT         9998 a         7970 c         6448 g        10668 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaagga ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taataaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgattttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactatt gaaacaatag aacgtaaata atgataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gtatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaactgatt aggaaattta aaccaacttc taacaatctg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag cctcaggttg ctcaaaacac tgttttgagg
      661 ttgtggatag aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt
      721 ttgaagagat tttcgaagag tattagaaag ctcgatggac tattccagat tcattccact
      781 agatttcgaa atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt
      841 tcggcatacg gcggttcaac taactgttaa cgcatgtcat tcaaggtaat aatccaaaca
      901 cgaaaccagt ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
      961 ctgagctact aattgatagt ggtcgcccca gccagatacc ttatccgcta tataggcctt
     1021 attatcacgt tcctgttcgt agagccacga tttcgctatc ccttcctctg acgattctta
     1081 tttccagcgt cagacttaaa acggtctatc cccagaccgt tttaatccgc tacctcacga
     1141 tagtcagact tgggaatcgc tattgggttc accggtagca ggtgcccacc gaggacttac
     1201 acctcaaata tataataaaa tgaaataaga ataggacgaa tcgatcagga cagtcaaatc
     1261 aatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa
     1321 catgcccgtc gtacatcaaa aaaagttgag acatagcgtc ttcaactttt ttacattact
     1381 ttaactactg attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg
     1441 atagtcaagt ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt
     1501 tcgttgaaag ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg
     1561 attgcttgaa cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct
     1621 tcaactgctt tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta
     1681 cgtggtccaa ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata
     1741 actacgtcga agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca
     1801 aagtctgcac cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca
     1861 cgtgaagttt taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct
     1921 tttttaacgt cgatgttcaa attgtaagca acttctacag ttgcatcaaa ttttgcaaag
     1981 ttagtttctt ttgcaagtgt tacagcttct tctacactgt atgcttttgt gctgtcgatt
     2041 ttctcaagag cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag
     2101 tggttcaatc gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt
     2161 tcagtctact atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag
     2221 cctcagtcac ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt
     2281 gttattgatt agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc
     2341 attgcagact ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt
     2401 acttgtgcac gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca
     2461 acacctgcag cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat
     2521 gatttatctt cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta
     2581 cgagcgttga actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt
     2641 ccaaccggtg gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg
     2701 acttttttag ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac
     2761 ctcccacaag tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa
     2821 gagaaaactt tcatttttaa tcgacataat cgccgccttc aaagccatag tactcttcca
     2881 aactgagacc acttgcagca atttctttgg cttcttttcc aacgtagcgg agatgccatt
     2941 cttctgccat gtagccagtc tccttttcct tgcctttaag atagcgaaca acaaagccat
     3001 agtcagccgc atggtccaag agccactggg ctgccttttc ttcagtaact aaatccccat
     3061 ctgtcccaat caaatcaaaa gcaagacccg tctggtgttc actgtaacct gggcgtgctg
     3121 agtagcgatc tgctgcttcc ttaccatctt gattgacata gtcttggtag agcttagcct
     3181 gagtttcata actcctaaac ccactgtatt ggtcactgat tggatagccc tcagcctgca
     3241 tagctgcgat tagtttgagc aactctgcct tggctgttgg attttctcct ggattgtaat
     3301 cttttgacaa aggataacgt ttattagcta ggataatctc atcgtatttc ccttggatac
     3361 tataatagct ccctttattg ctaacttctg cctttttctg actagaagct tgagatttgc
     3421 tacctacagt tccttccggt tgactgcttt gctccgtttt ttgagtgttt tcttcaactt
     3481 tggttttttc ttgcgaacaa gctgcaaggg tcaatgctag taaaccagat aaaatgacat
     3541 atcttttttt catttctttc ttcctctctc ttaggccaaa tacttctcca attcatgaga
     3601 taagatttta atcatctctt ccagctctgg cgattgtact tggcaatctt ctgccgccat
     3661 ttcttcccag ggcacccacc agactgggcc acggccattc aaaccgtgac tcttcatatc
     3721 acctgctctt cggggaaaaa gatgccaatg agcgtgggca tcgccatttc ctaggagttc
     3781 aatattcatc ttttcagcct caaatgcttt ggcgactgct tcttggacta aactcatttc
     3841 ctctaaaaag cgaagtttta cagaagtttc catatgatgg agttctgtga catgatcttt
     3901 tgctaaaaat aaggtatagc ccttaaagta ttggtagtca ccaataacaa catagcctgt
     3961 ttctagttct tttacaaagt agggattttg cccagcttta atgagttcga ttctctgaca
     4021 gattaagcac attctatgat accgcctcgc tcttaagata agcatcaacc atacgctcag
     4081 tcgctactac tgaatcgatg tgggtgcgct cataagagtg actggactca ataccagctc
     4141 caagaagtgc atgcttgacc tctgcacctg ctgacatcgc tgctgaagcg tccgatccgt
     4201 aaaatggata gatgtcgagc ttaaatggaa tatcttgctc tttagccaag gcaaccaagt
     4261 gttgacggaa gtcatagtga taaggacctg aagcatcctt gacacagata gatactgtgt
     4321 actcatctgt ctgctggtca tctcccatag ctcccatatc cacagccaga tattctacta
     4381 cctgagcagg aatgttagaa ttagcaccat gtcctacttc ttcaaaaact gaaaaagcaa
     4441 aatgagttgt tactggcaat tcaatcttct ctttcttata aatacgaagc aggttgagca
     4501 aaatcgctgc gctgacctta tcatccaaat gacgagactt gataaaacct gtatcagtca
     4561 caacagttcg tggatcgaag ctgataaaat caccgacctc aatcccaaga gcacgagttt
     4621 ctttttcatt gcttactttt acatccaaac gcacttccat attgtcctgc gtgcgttctg
     4681 cagttcctgc atccttgtag acatggcaag aagtttggtg gatgaggatg gttcctgata
     4741 ccttttgacc tgtgctagcc acatgaacgg tacagttttc accttcaatc atgttccaag
     4801 gaaaaccacc gatacggtcc aatttaagac gaccatctgg tttgacagca cgaacaatag
     4861 cacccagcgt gtccacatgg gcagtcacat agcgatgttg ctcatcattt tgacctttga
     4921 tggtcacatt gacaccaccc ttggctgtgc gaactggctg gtaaccaaaa ccttctagag
     4981 tcttgactaa ataattcgaa atttcacgag tgaagcccgt tggcgatgcg atggctgtca
     5041 gttctttgat atattctact gtttgattca tttcttcacc tctttcgcta cctattataa
     5101 cacatttatc atcggataaa aaaagaaaat cactcctgta gacttggcta caaaagtgat
     5161 ttaagtgatt attccatttc aaaaacatcg ctttcttgct tgtttggtag aaccaatgag
     5221 agcaagattc caacaatggc tggcaccaac catgggagag atgccttggc aaaaggaaga
     5281 acgctaacaa gatttgcaag aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg
     5341 gcaataactg taaccacagc aattgtcaac tgcatacctg gttttgaaag ggcaacaaat
     5401 ttgttgacaa tgacaatcat aacgatagca atcgtgattg ggtacaagat aaccagtact
     5461 ggaattgagt acttgataat cgcatcaaga cccaaattgg caatagcaaa tccaatcaag
     5521 gtaaaggctg tcgcataaac cttgtagctg atttgtggga agcgctcatt aaagaactca
     5581 gctgttgaca caatcaaacc aacagtcgtt gtgaagcagg ttacggtaac catagctgca
     5641 aggaagagtt gagctgttga gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca
     5701 cctggtgttc cacccttcat cgcttcagct ggtactggga aatgatttcc aagaaaacct
     5761 aaaccgatgt aaagagcgct gaaggcaagg gcaacaacga taccaacaac ccaaatagtt
     5821 gaaatgtatt ctttcttact tgaaaatcca agttgtttca aggtttgaac tgcgattacg
     5881 ctaaaggcca ctgaagcaag ggcgtccaag gtattgtaac cttctaggaa acctgtacca
     5941 aaggcagaag cttgataagc agctgaagca gcttgaggac ttgttccacc atatttgata
     6001 gctcccagaa cgaccaagat aacaatcaaa attgcaaaga ctggcgttaa aatacgtcca
     6061 atgcggtcta agatttttga tggattaagc gaaatcaaat aggctgccgc aaaatacaga
     6121 accgtaaata caatcaagcc aagtccttta tttgcatccg acaaaagggg gctaatccct
     6181 acttcgtaag ctgttgtagc agtacgtggg gtagcaaaga atggaccgat tgacaagtaa
     6241 agaactgaga ggtaaagagt cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata
     6301 tatcctttag gatttagcgt tccaataata agggtcaaga cggcgatacc aacgcctgaa
     6361 aagacaaaac ctgcgatggc aggaagaaaa tgttctccag atagagcacc tagagaaggc
     6421 ggaaaaatca agttccccgc accaaaaaat attccaaaca ggagcaaacc tgttagggta
     6481 ccttttttag ccataaaaat ctccttcata tttataaaat actgacctag tataccacga
     6541 ttaggagtct gaaaaaagca tcacgaggca aatattaaat gttttcaatt ttcttaaaaa
     6601 taagaattat ctaaaaataa aactctccta ctcagtccac accaagtagg agaaatgcaa
     6661 aattttaaag ttcttcaaag gctaacatgc caccctggac attgataaca ttataacctt
     6721 gttctaatag gaattggcaa gcacgcgccg atctcattcc agatttgcaa ataatataat
     6781 gcaagcgatc tttgtccaat taatcataac tatcagccaa ttgactaagc ggtaggttgt
     6841 gggcaccttc taaatgaaga gctgcaaact catccacttc tctcacatcc actaaagaaa
     6901 gctggtcgtt ttggtaaagc tggtaaaatg cgtcaaaggc tatttctttc attctttttc
     6961 ttctaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatat
     7021 gtaactgact tcgtcagttt tatctgcaac ctcaaagcag tgctttgagc tgacttcgtc
     7081 agttccatcc acaacctcaa agctgtactt tgagcagcct acgactagct tcctagtttg
     7141 ctctttgatt ttcattgact ataaaatggt tttaattctt tttttcaaat ctggcactac
     7201 ttctgcctca aaccaaggat ttttggccat ccagatttga tttcgtggtg atgggtgaac
     7261 tagcggaaaa taggctggca gatagtcttt atagtgtttc accctctccg ttaccttccc
     7321 actgattttc tcctgtaaat agtaggcttg ggcatattgc ccaatcaaga gggttaactg
     7381 aatatcaggc aattcctgta agagctgcgg atgccatttt tctgcaaaac ctgtacgagg
     7441 cggaagatca cccgacttgc catgtcctgg aaagtagaaa tccataggca aaacagcaaa
     7501 ataacctgaa ttgtaaaagg tatcttcatc cacacctagc cagtcccgca agcggtcacc
     7561 acttttatct ttccagtaaa ggcctgcttc ttgagtttta agtcccggag cctgaccgat
     7621 gatattgatg cgagcagttt ttggcgctgc aaagagaggc tcaatgccac gctctgtata
     7681 gctggcattc tgtgaatccg ccatgatagc ctgtttgatt ctttcgattt gagacatcta
     7741 ctttccctcc aaaaagaagt ccaagcataa gatctcagac ttctatcgtt ttatttgatc
     7801 aattcgtaaa tagcttcggc ataaattgct gctgctcgga aaagatcatc caaggcgata
     7861 aattcattgg cttggtgcat ggtatcaatc gagtctggga acatagcacc gtaggcaact
     7921 ccgcgttcta gcaagcgacc aaaggttcca ccaccgatga cttgttcatg acctttaagg
     7981 ccagtttgtt tttcatagac attcaacaag gtttgcacaa gtggatcttc cattggcaca
     8041 tagtgaggcg tgtgaccgtg ttcagacagg ctaacagaaa caactggcaa gttttcaagg
     8101 attgacttga tttgttctgg acttgttcct tttggatagc ggatgttgag ggcaatggta
     8161 ttatcagcac ttgtttcatc gaagcggaag acgccggcat tcatagaaag agcacccatc
     8221 ttttcatcca catgagcaat cttaagattt tcaccctcat gatcgttcaa gagaatttta
     8281 cctgcgatgt caaggtaatc tttggctgga ccagcaaagc caaactggct gaggaagagg
     8341 gcaaggtaag ttgcgccatt gacacctgaa gcaggcatag caccgtgggc tgatttacca
     8401 atgatcgtca ccttgtattt gccagcttct tcttggagtt ctcctctaag tttgtgttct
     8461 gcaacaaagg catctagttt agcttgcaag tcagccaaat cacctgaaac gactgctgtt
     8521 gctgattctg gtaccatatt ttcacgtaaa ccacctgtaa agctgtgaag acgggcagca
     8581 cctgtatttt ctcctgcaaa gtggaggtat tccgtgatat ttcctttttc accattgatg
     8641 attggaaatt cagcatctgg tgagaaaccg aaatctggtt tggcaagtcc tacgtgctca
     8701 aagtagtagt ccatgtctgc ccagcctgat tcttcgtctg ttccaacgat gaagcgaatt
     8761 ttcttagaag ttggaagacc caattctttg atgattttca aaccatagta acaagctgtt
     8821 gtaggaccct tatcgtccga agccccgcgc gcataaaggc gaccatcttt gatagttggt
     8881 gtgtaaggaa ctgtatccca accgctacca gctggaacca cgtccatatg ggcaaagatt
     8941 ccgagaactt cttctccatc accaaactca aaatgtcctg cgtagttatc gacattctta
     9001 gttgggtagc catcgcggtc tgcgatttca aggaatttct ccaaggcttt tactggacca
     9061 ggtccaaatg gatgctgggc atcagccttg ctatcatcac gttctgagtt gatttccaaa
     9121 aggctaaaca agtcagccaa gaggtcttct ttgcgttttt ctacttctgc tgtaaaatca
     9181 attgctgtca ttttttcttc tttctatctt ttctcgatga tttcatctac tggcaagcgg
     9241 tagcttggtt ccaatttttc gtctgtataa cccactgtga tcaagagttc tgggcggaaa
     9301 cggtcttcga tttccaaaac ttcattaact tttgatttgt caaaaccaag aataatgtta
     9361 gaaccaattc cttggtctgt caatgcaaga accaagttca tggcaaccaa acctgcattg
     9421 agagctaggt agtcgctgac ttgttgctca ttgtaacggg caaactcagc tggcaaattt
     9481 ttcatgaagt attgaagttg ttcttctgag aaattgttag caccaccaac tcgggcaatc
     9541 ttacgagcgc gtttggcaag gtctgtatct gtaaataggg caatggttac aggtgctgat
     9601 gatacctgct caaagtttga accataagcc aactttgcca gttcagcatt tttctcacga
     9661 acaactacaa atttccaagg ctggctgttg tgggcgcttg gcgccaaggt tgcaatttcg
     9721 atagccgtac gcacatcttt tggatcaaca ggcttatcag taaaatgctt agtcgcatga
     9781 cgttttttat ttaattcaag aaatttcata atcgatttcc ttttctaatt ctactgcttc
     9841 cattctacca taatttgaaa gagcttgcag ggatttttca tgattaagtt tttctatcac
     9901 agacataaaa gatatatatt ggtttatcag gaaagtttct gataaactag caagtacttt
     9961 acatttgaat ggagacagta tgaaaaaatt tagcctatta ctagctatcc taccattttt
    10021 ggttgcctgt gggaatcaag ctacacccaa agagactagc gctcaaaaga caatcgtcct
    10081 tgctacagct ggcgacgtgc caccatttga ctacgaagat aaaggcaatc tgacaggctt
    10141 cgatatcgaa gttctaaagg cagtagatga aaaactcagc gactacgaga ttcaatttca
    10201 aagaaccgcc tgggaaagta tcttcccagg acttgattct ggtcactatc aggctgcggc
    10261 caataacttg agttacacaa aagagcgcgc tgaaaaatac ctctactcac ttccgatttc
    10321 caacaatccc ctcgttctcg tcagcaacaa gaaaaatcct ttgacttctc ttgaccagat
    10381 cgctggtaaa acaacacaag aggataccgg aacttctaac gctcaattca tcaatcactg
    10441 gaatcagaaa cacactgata atcccgctac aattgatttt tctggtgagg atattggtaa
    10501 acgaatccta gaccttgcta acggagagtt tgatttccta gtttttgaca aggtatccgt
    10561 tcaaaagatt atcaaggacc gtggtttaga cctctcagtc gttgatttac cttctgcaga
    10621 tagccccagc aattatatca ttttctcaag cgaccaaaaa gagtttaaag agaaatttga
    10681 taaagcgctc aaagaactct atcaagacgg aacccttgaa aaactcagca atacctatct
    10741 aggtggttct tacctcccag atcaatctca gttacaataa tactcttcga aaatctcttc
    10801 aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacct acggctagct
    10861 tcctagtttg ctctttgatt ttcattgagt ataagatata taaaagcgat tggactacca
    10921 atcgttttta gtttgcattg gttattttag gaaactctta caaaaaatca aaaaaattct
    10981 tcacatcctc tacataccca tgcttttcta ttaagctggc taaaagttcc agattgtgcc
    11041 cctgatagtt atcgtcacga cgcagttctt catacatttc aataaaggga agccccttgg
    11101 acttggccaa ttctaactca gcctcgtaat cataagcaac tttacgaaat tggatattga
    11161 ccaattcccc atcttcaact tctatcacgg catactgggc acggtgattt tttaacgcct
    11221 cccaattaaa atagggcatg ccaatcgacc ctggattgat gatttgttgc ccttgacttc
    11281 cataacgaag caactgcttg tgaacatgac cataaactgc cacgtccgtt tccgcatcta
    11341 gcagttggtc aaatttctct gtatcattct caactagcaa gtcaccacca tagttcttat
    11401 ttggcaaatt atgagagata gaaaagcgca atccgtcaat ttctttcttt tccagcaaag
    11461 gcaagcttcg tagccagaca atcgttgcag gatccattcg ctccatcaaa aactgggtca
    11521 tgcgcattga ctggatttct ttcggatatt ccaaaccata ttcgccatcc aagacctcca
    11581 ggacacgatc atcccaattg cctcgaacac ttgctgtgat aggaaggtcc tttagcaggg
    11641 cgactaagtc atttgcgcct ggaccaggaa gaaaaatatc tccctgaagc caatattcac
    11701 tggccccttg atttttagca tctgcaatca ctgcttctag cgccgtcgca ttgccatgaa
    11761 catctgataa aattgcgatt ttatggttca ttgtggtttc cttccgtttg gtaatctact
    11821 ctttcttctg ctacttgagg caaggcttct ccctgcgggt tcaactttct ttgcacagcc
    11881 tctgcaacga ctctaggtac cccaacttcg acaatctcat ccacactggc ttccttgatt
    11941 ttggtcaaag acttgaaatg cttcataaga ttctgcttgc gtttaggtcc cagaccgtca
    12001 atcccatcca attgagatga gaaagaattt ttggagcgca gttggcggtg gaaagtgata
    12061 gcaaagcggt gcacctcatc ttggatgcgt tggaggagga aaaattcctg agaattgcga
    12121 gacaagtcca ccacctcaag cggatctcca aagagcaatt catgggtttg gtgcttatca
    12181 ttcttttgca gcccagcaat tggaatatcc aagcccagtt cctcttggat gacttgctta
    12241 gcaatattga cttgaccttg ccccccatca atcacaatca aatctggagg agtcaaagcc
    12301 tcacgctgta ctcgaccata gcgtctgcga atgacttctc tcatactagc atagtcgtcc
    12361 ggcccaacaa cggtttttat cttgtactta cggtaatctt ttttacttgg cctgccgtta
    12421 acaaagacca ccatggctga aacaggactg gtccccatga tgttggagtt atcgaaggac
    12481 tcgatgcgaa ctggagtcgg aatttggagc aaacgtccta gattttcaat agctccttgg
    12541 gtcttttcga ctgatttttc tagcagattg aacttctgct ctagactaac acgagcattt
    12601 tttatggcta gattgaccag ctgttttttc tctccacgtt ggggtttgag aatcttggta
    12661 tccaccaaag ccttgacagc ttcttcgtca atatcctgcg gaatcagtac ctcattggga
    12721 actaggtgag atttttcttg atagaattgt cccacatagg tcaagaaatc ctcatctgga
    12781 tcattgaagt aggggaagag attgacatcg cgctcgatga gcttgccctg acgaacaaag
    12841 aaaacctgca cacacatcca gcccttatcc acatagtagc caaagacatc gcgattttgg
    12901 agatccttag ccatgacccg ttgcttggtt cgaagtgttc caatggcctg aatcaggtca
    12961 cggtattccg ctgcccgttc aaactccata ctttgtgctg ttactgccat tttactcttg
    13021 agatcatcga tgattttgtc atcctgacct ttcagaaaat cagacacctc ctgggccatg
    13081 gacttgaaat aggcctcgtc attcttacag atggtgtggg ccatacattg gccgatatgg
    13141 tagtaaaaac agaccttaga gggcgggttg gtacattttc gaaaagggaa aatcctatct
    13201 agaagtcgct tgatttcatt ggctgccccc acatctggat aagggccaaa ataaagacca
    13261 ccgtcctttt tgacctgacg agtaatgata agccgtggat agtgctcatt ggtgattttg
    13321 ataaaaggat aagacttgtc atccttgagc atgatattgt acttgggctt attttccttg
    13381 atcaggttga tttccagcag aagcgcctca atattagact ccgtaacaat aaattcaaaa
    13441 tccacaattt cagacaccaa ggcctctgtt ttggtatcat gacttccacg gaaataagac
    13501 ctcacgcgat tacgcagatt tttagccttt cctacataga taatggtgcc gtttttatcc
    13561 ttgtaaatgt agcaaccagg gctggtcggc aagagctcta gttttggttt aatcaagttg
    13621 ttcatagttc cattatagca aaaaagtagg gaaagatagt accctactca ttagtctcat
    13681 atatttttcg gaggtttgca acatcctctt cctggatacc ataaaaggaa cctgctggtt
    13741 gcatgacaga cttctcatct gtatggtcca agccaatcgc atgacctaac tcatgttctg
    13801 ccgtatggac aaggcgttca taggaatagc catagtatgg attggacaaa taataatgat
    13861 tcaaccgcac cgttacggac aagaattgcc ctgttaagag attagtttga ctttccgcct
    13921 ctcctgccac aggagtgcct ccgtcgttca tctccgtagc cgtaatatcc gccttactag
    13981 actcagtcac gagttcaaag ttaaaagcac cagtttgatt ccagttctgg attgcttcta
    14041 aataagcctc ttgaaagcgt gaatccatct gcggatccag gtaaatacga gcagaggcct
    14101 gtggccacct tccttcagaa tgctggtgac tatctgtctg gcttaactta ggcagttgcc
    14161 ctgttttctc ccattggtca atactttgtt gaccaatttt tactgaccgt tctgcttgct
    14221 ttagcgctcc ttgaaaatcc ccgttcagat accagagaag tccgaaagca agcacacata
    14281 agagcacaac tatccaaacc agacgccaaa acaaacgcca cacaaaagaa aagaaagccc
    14341 ctatcaaacg aaaaagccag cgcatgtctc tccacctttc tagcaaataa aaattatttt
    14401 actaaaagaa gctaaaagaa atctaaatac tgactttttc atcttaacgt cctactattt
    14461 ttttgagtaa ctggatagct ttgtatttta aaggagatgg atggtaacgg aaagtacctg
    14521 ctttgcgtac aatatagcca ttaaaattct gtttaaaacg caaaacacca tcacttccat
    14581 caaaaatccc ttgaatgcct aggaagttgt atttaggtat tccacgtttt atgctttcca
    14641 acataacata tttttgaagc agtgcagggg catagaactt attaaactca gtgtaggaac
    14701 cactaaagag ataagtcgtt tcctgaggca tataaacaaa taaactccca gctaaaacaa
    14761 tatcttcttc tccatatttt tcaatcaagt ctcgcgcttc tgcttttcga acttcaaacg
    14821 tttcaaattg actagaatat tctctcagtt gattttgttt tttctcagaa tgaggatttt
    14881 tactcaaatc aagtcgcaac ttgtccaagt tttcttctag tttattttgt tcaccttgca
    14941 atttgctcat atagtccgaa aaatttaagc ttgctatgag aaactccgct tgttctccaa
    15001 aagtatcata aaaatgctca taatattcta aacttttatc actatattct ctacgttcag
    15061 aggtttcttt tgttatattc ttaaaaatcg atagttcttc acgttttaac tttttcaatc
    15121 gaatgccaaa ggtttcagcc tttttcacca agggtttacc ctttttgcta aaacttttaa
    15181 gcaaactctt ttcagttaat tcagttaaat ctttatagta taaccaatct ggttctccac
    15241 ctgggtaacc tgttgttaag ccatcaaatt gataacctaa atcagtcaaa ccttgaataa
    15301 tacttttttt ctcagcatct attggattac cttggctatc aaaagtttga taagtttcat
    15361 aaggttttac aagcaactct aatacaccat tttgcttggc atattctttt aactctgcat
    15421 aaaaaactgg aagagcatct tgttgggtat aaatcggccc cgaattgagt tccatatgca
    15481 gaccacccag catgggcaag ctataaacca gagctgcaac ttgaatttct ccttcttgtt
    15541 tcaaagcaag ataaacaatt cgagcccctc ttttttctag caaatccccc atctggacag
    15601 attgcataaa ggaacgagaa gaaacctgat cagaataagt ctgaaactct tctttcgtga
    15661 gtgttgttag tgccatatac ttactttcta tgtttttttc ttaatgtttt acggaaatca
    15721 agagcaagtc ttaacagagg atagagagga tgagtgggca ttgtaaattc acccaagtat
    15781 tcttcaatcg ttggattaaa tttttcctta aaatgataaa gtccaccatt gagagagttt
    15841 tcaacaccac ctaaattttg ccagaccata cctcgctcaa aggcatagcg agccgtttca
    15901 taccatgtta aaattggtgc attgtaacgt ttaaaatcat catccatacc agcatatata
    15961 ttgacagagg tagtaccaaa ttccaaactc aaagtagccg ctaaaggaac tctcgcttga
    16021 cctacatcta tatattcctg caagaaggtc aattcctcta acaaacgttc tttttccttc
    16081 ttctgcgctt ctacttttga agttcgagtc gactcagtaa aggtctcttc caaggctcta
    16141 tttttcgcta actgttcttc taattcttgc gaacgtttag aaacatccaa ggtggccaag
    16201 gtgatatagg ccttgtcctt aaaattatct aacaattttt tataataggc ttcattcctc
    16261 aaatgaatct cttttcgctt ctcagttttt ttcatcaact ccgaaaatga atctaatagt
    16321 tccagtccac catattgaat ctcaagccct ttgtttcgtg ctgttcgaat agcctgtttt
    16381 gttgacttgg aaagtttatc ttcttcaaaa ttttccttgt atattttcgc ctgaatacga
    16441 ggttgaatgg tgtctcccat ttcctccgtt tttcctgacc accttactcc catttgttgc
    16501 aaactatcaa taatagccag attttcagga aattctgtct tttcctgatt gattaaactt
    16561 tgagataggc aaatacttgg gtcaaaagtc acaaaaaccg ctctcttact gcgagcatag
    16621 gacttaatag actgaatggc aaaattcaag agttctttat ccccataatc caatataggt
    16681 cctcttggga tgtaaaacat tttatagcct agcggaagag ttctaatcaa aatactagct
    16741 gtcgccagta atttttcttc cctgtaaaca ccaaacttct catgttgcca attagactta
    16801 acttcctccc aagcactact ttgtaataca ttggctaatt catgttcttt gacaaactga
    16861 tcatattcta atgtgggaat gccaatttga taacggtaca tttcctactc tttttcctcc
    16921 agtattttat tactattcta ctactttcgt ttgaaaagtc tagtgaaaac atattttatt
    16981 ttagttctac tccccctatg ctgaagttca aactaagtca gtctctcttc taatttgaaa
    17041 tcaattggta gggttgttaa aaaaacttcc aattgttttt cccagtagta ccactcgtga
    17101 gttccagcgc tatggctata ggtcacatca aaacctagtt ttttgagatt tttcactgca
    17161 agattattgg cttcgtacaa gaaatcctgt tcgccacacc acgcccaaag tttggtcttt
    17221 ttatccgatt ttttagccag actttcaaga gaatagggac tagttgtcca gtctttaatc
    17281 tctccaaaaa cacctctcca gtatgctggc gttcccagat tttgactctc aggagaaaaa
    17341 tcttgaaagc tcaatgcacc tgaaaagcta gctgcatgag aaaaacgatt tgtcgcaaga
    17401 gccagtttga agcagccgta gcctcccata gaaagaccag cgataaaggt cttttcacgc
    17461 ttgctagtca tattagggaa gaagcgtttc agaacctgtg gcaattcctc tgctagagcc
    17521 gtgtagtagt caaaaccata ctgggtatcg gtgtaccaac cattgctggt attgggcata
    17581 acaacgatga gattagttgc tcgaagcaag cgttctacat tggtccgctt aaaccaacta
    17641 ttatgattgc cagacatccc gtgcaaaagg tacaagacgg gaatatcttc acactctggt
    17701 tcttccactc gattggcatc agggtagagg acattcaccc cccactccat atccaatact
    17761 tgtgagtaat actcgatttt cattactgcc atgattttct ccttctattt ttctattttt
    17821 ctataagaaa aagccgaaac tcgactttct ctctgtttat ttcaacgatt attttgcttc
    17881 catgactact ggtaaaatag ctggacgacg cttggtttgg tcaaagagat acttggtcaa
    17941 attatctcga accttccctt taagatctgc ccagtcaaag tcatctcctt gaagatactc
    18001 ttctaccgtt tggttaatca attctgaact ttcacggaga atatcgcgac tcttcttgag
    18061 ataaacaaat ccacgcgtgt gaacacgagc cctagccaca attttcttct cacgacggtt
    18121 gactgtaata gccacgatga aaattccatc ctctgacaag accttacggt cacgaagaac
    18181 aacatttcca acatcaccaa tggcattccc atcaatcaag atatctcctg ctgaaaccga
    18241 tccagctgga acaaagtctc cattctcgta agccatggtc gtcccctttt taggaatgaa
    18301 gatgcgttct ggcaacatcc caactgccat ggcagcctta gcgtgagcat ccaactcacg
    18361 atactcccct tggacaggga agaggtactt aggttgcaaa agattgatca tcagctgcaa
    18421 atcacgcaca tttccgtgcc ctgatacatg taaactttgg gtaatcaatt tgacaacccc
    18481 acctgcctga taaatcatat tttccacacg cgcaacaaag gcttctttag caatagacgg
    18541 agccgtagca atatagacca ggtcgccatc cttgatttct acataacgat ggcgaccaat
    18601 cgacatctta cgaagtccat tgataggttc acccatacga cctgtctcaa gaataatcaa
    18661 ctcatggtct tcaaagcgag acatatcttt aggcttaatc aagagaattt cgttggctaa
    18721 agacaacttc ttaagacgaa tcgctgtgcg gacgatattt tcaatatcaa atcctgtcaa
    18781 gacgatacgt cgacctgttt tatccgcagc gtcaaaaatc tgctgaatac gagaaagatt
    18841 actggaaaca gctgcaacga tgatacgacc ttcccagtca gcaatagttt gggtaatttc
    18901 atccctaact tcactttcac tagccacctg aatattgctg tctgcattgg ccgaatcact
    18961 gaggagagcc aggacgccgt cacgaccaat ctctgccaaa cgagcaaaat cagttgcata
    19021 agattcacta gccgtttggt caaatttgaa gtcacctgta taaacgatgc ttccttccga
    19081 tgtcttcaag acaattccca gactctctgg aacggagtaa gtcgtaggga agaaggaaac
    19141 cactgtccca ccaaaatcaa tctccgtatt ctcatcaatg acatggaaat cattaaattt
    19201 cttaacggca tcatttcctt tgacaaagag ctttgccaac tcaatggtca actcagaccc
    19261 aaatacagga actttagcct ctgccaagag ataaggtaga gcaccaatag catccgcatg
    19321 cccgtgggtc aagaaaaccc cagcaatacg gtcgctattt tcaaaaaggt aatccatgtt
    19381 tggaatcacc acatcgaccc ctaattgttc attttcagga tattttaacc ctacattcaa
    19441 aacaaaaatg gactctccaa tttcagcaat gtacatattt tttccattct cacgcacacc
    19501 accaagtgtt gttaaactga tattactcat ttttcctcca aaatcttagt ttatcttgat
    19561 tatagggcaa ctctaccctc ttattctaaa agttctaata ctttcagccg aatcttttcc
    19621 taccattata ccattttttt gatgattttc aaaatgaagg tctgttttca aaaaagagtt
    19681 gatttcccaa ctctttccta acttctactc tttttccatc aaaaaatcat aaatttcttg
    19741 caccgtaccc agcgccatca tttcttggtc tttaacggtt tgtttgagat tttggtaaat
    19801 ttgactttct cctatctccc gctttggcgc ctctttattg actgtcatca caccatcttt
    19861 tatcgtcaca aagcctagtt cttcaaatac ttgaatcatc ttgaccagca agatttgttg
    19921 aatattaaga tatgcagcca aatctttcag cttgtagcga atatcaaact ctgggaactg
    19981 gtaaatagtc ttgtacaatt tggcaaactg atctctagtc ccataacctg tcagataata
    20041 ggccttgtca atatcatttt tgaaatagac agcagagaaa tgctgttcct gaaaaatggt
    20101 cttcagctga gtaatatcct ctggaatgtt ttttacgaca acagcttcac tagccgcaag
    20161 atttggcagt tctccaggaa aatccaagac tggaacacct tctggcaaga ctgtattttt
    20221 tccacgaatg ttaaaaagtt gaacaccttc cactcgcgca tccaccatca tcaactggag
    20281 ggcagtttgg ccattccatt ggttgacaga caatttaacc gctaactcta gattcttggt
    20341 ttgagaaaac tctgtcgccc atctgccttg accaaaggct accacttcaa aactcgcctc
    20401 acccctggaa attttcagct ttagatgggc attacctgcc cccatagtac gagcactttc
    20461 gacctgaaaa ttcttgatat aaaaaatagg tttctgatta tccattccaa aaggagctaa
    20521 acgttcaaaa cttttgaccg tttccaagct aagtgcctcc aaatccaact cttcatctag
    20581 gtttaactta ttcttgccac cagcatctgc acctttttca cgaacataat cttccaaaac
    20641 ctgagataaa tctgagagtt gctcaacttc cagcgtcata cccgctgcac ctgcatgacc
    20701 tccaaaggcg atgaagaggt ctcgatgggg atccagagct tcaaaaatat cgaccgcttc
    20761 cacactacga gcactgccct tggcacgacc gtcttctata ttaagaacaa tgactgtctg
    20821 tcccaattct tccaataaac gaccagccac gattcctaga accccaggat tccagccttc
    20881 cttggccaag acctgaacct tcttctcagg atccaccatg gtcttggctt cttcatagat
    20941 agactgaacg atttccttgc gctcttcgtt tttctggtga atcataaggg caatctcatg
    21001 cgcttcctca tcatcaaatc cagtcaacaa atcaatggca ggattgggat catccaagcg
    21061 gcccaaggca ttcaaacgag gagcaatctg gaaaccaacc gtttcttctg ttacttcgtt
    21121 agcagcaatc ccagccatgt ccagcatttc ttgcagacca atgcgctggg tatgacccaa
    21181 catttccaga ccatattgaa ctaagatacg attttcatcc gtcagactca ccatatctgc
    21241 aatagttcca atagcgacca aatcaagcaa ttccacttgc acttcttcta acagggcaca
    21301 agccaacttg aaagcaactc cacaaccagc caaatattta aaaggataat ccgcatctgg
    21361 atgttcagga tggacaatag cataagcatc tggcagggtt tcaggcatgg aatgatggtc
    21421 tgtcacaatg acatctactc ccatagactg agccaatgca atagcctcat gaccagcaac
    21481 cccattgtcc accgtcacaa tcaaggaaat tccttcttgc tcgataaagt atttataaac
    21541 actagcatta gggccatagc catcggtaaa acgatttggc aggtaaactc ggcactcagc
    21601 accaagttgt tccaaacttt ccttcacaat agaagccgaa gtcatgccat ccgcatcata
    21661 gtctccataa acgagaatat tttccccttc ttcaatagcc tgacgaatcc gctccactgc
    21721 cttgtccata tcatggagca gataagcatc atgtaagtcc tccaaggaag gttctaaaaa
    21781 cttcttcaga ctttcttggt cctgaatccc tctctcaaac aataaccgag ccacctcagg
    21841 acccagtcca gccttcttgg ctatctttgt aaaatccgca tcttctacct gcagggcaaa
    21901 ctgccattca taagtaggtg ttatcaaaaa gacatccact ctttctaaga attctattgc
    21961 ttcattataa catgatttag acgttttctc tatccagatt gcttttttat aacattttat
    22021 agtatattga aactagaata gtacacctct acttctaaaa tattgttaga aatcgatttg
    22081 actgtcccga tcaatttgtc ctgttcttat ttcactatag tgaatttttc agatatggtt
    22141 tgacaagaac attcttttat tgtagaatcg tgttataaaa tctaacgtaa aggagatctc
    22201 tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac cacgcactcc
    22261 gcaacatcaa tctccgtttt taaaaaggac aagttgttgt cctgcttgga ccttctggct
    22321 ccgggaagtc cactcttata cgtacgatca atggtttaga ggctgttgac aaaggaagtc
    22381 tcctagtcaa tgggcaccaa gttgctggtg ccagccagaa agatttggta cctcttcgca
    22441 aggaagtcgg catggttttt caacatttta acctttatcc acacaaaaca gtgttagaaa
    22501 acgtgacact tgcgcccatt aaagttctag gaattgataa aaaagaagct gaaaaaaccg
    22561 cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat cccgccatgc
    22621 tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg catccggaac
    22681 tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga gatgttctag
    22741 cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc cacgaaatgg
    22801 gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa gttttagtag
    22861 atacgacaga tgtcgataac ttttttgaca atccaagcaa acctcgtgcc caacaattcc
    22921 tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc tatgaaaaaa
    22981 aattcttttt atcagcatta ttgattagcc ttttcggcct tgctgctgcc aaaccagtcc
    23041 aggctgatac tagtatcgca gacattcaaa aaagaggcga actggttgtc ggtgtcaaac
    23101 aagacgttcc caattttggt tacaaagatc ccaagaccgg tacttattct ggtatcgaaa
    23161 ccgacttggc caagatggta gctgatgaac tcaaggtcaa gattcgctat gtgccggtta
    23221 cagcacaaac ccgcggcccc cttctagaca atgaacaggt cgatatggat atcgcgacct
    23281 ttaccatcac ggacgaacgc aaaaaactct acaactttac cagtccctac tacacagacg
    23341 cttctggatt tttggtcaat aaatctgcca aaatcaaaaa gattgaggac ctaaacggca
    23401 aaaccatcgg agtcgcccaa ggttctatca cccaacgcct gattactgaa ctgggtaaaa
    23461 agaaaggtct gaagtttaaa ttcgtcgaac ttggttccta cccagaattg attacttccc
    23521 ttcacgctca tcgtatcgat gccttttccg ttgaccgctc tattctatct ggctacacta
    23581 gtaaacggac agcactacta gatgatagtt tcaagccatc tgactacggt attgttacca
    23641 agaaatcaaa tacagagctc aacgactatc ttgatacctt ggtcactaaa tggagcaagg
    23701 atggtagttt gcagaaactt tatgaccgtt acaagctcaa accatctagt cataccgcag
    23761 attaaggagg ataccctatg acagatttat catcttggac agcctatttt caggattttg
    23821 gacaattttt caatggtttc ctctttactc ttgccctagc gattggatcc tttatcctcg
    23881 ccatggtctt aggaatcttc tttggtgcca tgtcaaccag taaacgtcca attttacgca
    23941 ttttagctcg catctttgtt gaattttacc aaaatactcc cctcttggtg cagtttgtta
    24001 ttgtttttta tggcctacct cttatcagtg accatatcat catgattcca atttattgga
    24061 cagccgttct ctgcgtggga ctctatcacg gcgcttatat cgctgaggtt attcgttcag
    24121 ggattcagtc tattcctagt ggtcagatgg aggccgcctt gtcgcaaggt tttacctata
    24181 tcagtgccat gcgcttgatt accttgcctc aggccttccg catcattctc cctccattga
    24241 ccaaccaaat tgttaacctc atcaagaaca cctctactgt agctatcatc tctggagtag
    24301 acttgatgtt tgtgactaag tcttggtcgg ctctcaacgg aaactatatc ccagcctttt
    24361 taggtgctgc tcttctctac tttgccctat gcttccctgt tgcccagttt ggtcgcaaga
    24421 tggagcaagc caacaaaaaa gcctattcac tttaggaggt tactatggaa tctattttag
    24481 aagttttaac cccagataac ctagtcttta tctttaaagg atttggcttg accctctata
    24541 tttctctgat tgccatcatc ctctctacta tcatcggtac ggtgctagct gtcatgagaa
    24601 atggcaaaaa tcctgtctta cgcattattt ccagtattta tatcgagttt gtgcgcaacg
    24661 ttcccaacct tctctggatt tttactatct ttttggtgtt caaaatgaaa tccacaccag
    24721 caggtattac agcctttact ctctttacat cagcagcctt ggctgagatt attcgaggcg
    24781 gtctcaatgc cgtagacaag ggacagtacg aagcaggaat gtcacaaggc ttcacctcag
    24841 cccaaatcct ctactacatc attctcccac aagccatccg caaaatgcta ccagccatca
    24901 tttctcagtt tgttaccgtg attaaggata ccagtctcct ctactctgtt atcgccctac
    24961 aagaactctt tggagccagc caaattctca tgggccgtta tttcgaacca gagcaggtct
    25021 tcagtcttta catcctgatt gccctcatct acttcagctt taacctagca atttctagcc
    25081 tgtctcatat gctagccaaa cgttggcaac aagctgcaga ataatactct tcgaaaatct
    25141 cttcaaacca cgtcagcttc accttgccgt atatatgtta ctgacttcgt cagttctatc
    25201 cacaacctca aaacggtgtt ttgagcagcc tgcggctagc ttcctagttt gctctttgat
    25261 tttcattgag tataaacagc cactctccag ttcaattgga gagttttttg atgagagtag
    25321 atatttatag acctcaattt gacaccatac attttctatg ataaaatgta acaaattcat
    25381 ttacaacaaa tcgaaatcta aatgaaatgg aattttctat gaaatcagtc aaaggactac
    25441 tctttatcat agctagtttt atcttgactc ttttgacttg gatgaacact tctccccaat
    25501 tcatgattcc aggactagct ttaacaagcc tatctctgac ttttatccta gccactcgtc
    25561 tcccactact agaaagctgg tttcacggtt tggagaaggt ctacaccgtc cacaaattca
    25621 cagcctttct ctccatcatc ctactaatct ttcataactt tagtatgggc ggtttgtggg
    25681 gctctcgctt agctgctcag tttggcaatc ttgccatcta tatctttgcc agcatcatcc
    25741 ttgtcgccta tttaggcaaa tacatccaat acgaagcttg gcgatggatt caccgcctgg
    25801 tttacctagc ctatatttta ggactctttc acatctacat gataatgggc aatcgtctcc
    25861 ttacatttaa tcttctaagt tttcttgttg gtagctatgc ccttttaggc ttactagctg
    25921 gtttttatat catttttcta tatcaaaaga tttccttccc ctatctaggg aaaattacct
    25981 atctcaaacg cttaaatcac gatactagag aaattcaaat ccatcttagc agacctttca
    26041 actatcaatc aggacaattt gcctttctaa agattttcca agaaggcttt gaaagtgctc
    26101 cgcatccctt ttctatctca ggaggtcatg gtcaaactct ttactttact gttaaaaatt
    26161 caggcgacca taccaataat atctatgata atcttcaagc cggcagcaaa gtaaccctag
    26221 acagagctta cggacacatg atcatagaag aaggacgaga aaatcaggtt tggattgctg
    26281 gaggtattgg gatcaccccc ttcatctctt acatccgtga acatcctatt ttagataaac
    26341 aggttcactt ctactatagc ttccgtggag atgaaaatgc agtctaccta gatttactcc
    26401 gtaactatgc tcagaaaaat cctaattttg aactccatct aatcgacagt acgaaagacg
    26461 gctatcttaa ttttgaacaa aaagaagtgc ccgaacatgc aaccgtctat atgtgtggtc
    26521 ctatttctat gatgaaggca cttgccaaac agattaagaa acaaaatcca aaaacagagc
    26581 ttatttacga aggattcaag ttcaaataag taatcatact ctcctgggat ttcccaggag
    26641 agttttttat agccaaatga aataagacag gaacgatgga attttggcat tcaaatcaat
    26701 tgataagaat gttttatagt ggagtgaaat aggatacgaa caaattgatt aggaaaatca
    26761 aatgaattta tagaaatctt ttagcagtta tgttatccta ttctagtttc aaaacgctat
    26821 agaagcagca ttgtgctagt ctagattcag tttactatac taaaacgagt agcttgaaat
    26881 caaaaaaccc accctcacag gcaggtttta tctgtattat tcagctagat tatgctttac
    26941 cttctgaacc gaatacgtcg atacgttctt caaccgatgc ttggatagct tttacaccgt
    27001 cagccaagaa tttacgtggg tcgaagagtt ttttcttgtc gtattctgct tcgtttgctt
    27061 cgtagtcacg agcaaattta cgagttgcgt tagcgaatgc gatttggcat tctgtgttaa
    27121 cgttaacttt ggcaacacca agtttgatag ctgcttggat ttgctcatca ggaatacctg
    27181 atccaccgtg caatacgatt gggaatcctg gaagagcttc tgtcaatttt tgcaagtggt
    27241 caaggtcaag accttcccag tttactgggt aagggccgtg gatgttaccg ataccagctg
    27301 ccaagaagtc gataccagtt tcaaccattg ctttagcgtc ttcgattgga gccaattcac
    27361 ctttaccgat gattccgtct tcttcaccac cgatagtacc aacttcagct tctactgaga
    27421 tacctttagc gtgtgctttt tcaacaactt ctttagccaa tttaaggttt tcttcaactg
    27481 gaaggtgtga accgtcaaac atgattgaag tataaccaac ttcgatacac tcaagtgcat
    27541 cttcgtagtg accgtggtca aggtggatag ctactggtac agtgataccc attgattcaa
    27601 caaggttagc gatcaagttg cgagcaactt tgtaaccacc catgtattta gcagcaccca
    27661 ttgaagtttg gatcaaaact ggagcttttt tagcttctgc tgcgcgcaag atagcttgag
    27721 tccactcaag gttgtttgtg ttaaatccac caactgcata accgttgtca cgggctgctt
    27781 ggacaaattt ttctgctgaa acgattgcca ttttatcagg cctcctgtat atttttatgg
    27841 gtcatcccat ttacattgtt cattttatca ctttttgcca aaaaaatcta gtttttcccg
    27901 cagtttcgat tgattttctt ctaactccat ctatgtaaac cctttctctc cctagtcttg
    27961 gacgactttt ggaaaatcta taaagaaggt taaacgattc tcctccatct cgaaacgata
    28021 agctaatttt tcatgttcta atagactctt aaccacaaag agccccatac cagacccctt
    28081 gaccttgcga ctagcattgt cagaaaaaga ctgggctagt ttttcttgtt cctctgagct
    28141 acagctattt tcgataaaaa gttctccttc tctttctcca attcgaacta agccacctgg
    28201 aacagagtgc ttaatggcat tgctgatgag attagaaaga atcaacttca taactgatgg
    28261 gtttagataa gcctgctgat gggtcaaact attgtctatc tggagctctc tttccttggc
    28321 tagcaaggca taatctttga ccagattttg cgtcatctgg aggaggtcaa ttgtttccct
    28381 atcatctcgc aattcctgca cagaagagag ggaaagtatc tgcagaacat ggtgattgag
    28441 ttcatccaca atccccaagg caactcccag atactggtct ctatccttat aacgaccgat
    28501 attctctctc atattttcga ttaggatttt caaactagcc agcggtgttt tcaattcatg
    28561 agaagctcct cgtaggaatt cgaccttcat cttctccagc tggagaatgg cttcattctt
    28621 ttcatgcaag tccgcaataa cagtcaagag atgctggtag aggctattga tttgttcctt
    28681 gagattacct atctcatcct tagaatccac gcgcaatcgc acttgggaat ccaggtccat
    28741 catccgacgg gtcacccgct tgatttccaa aatcggtgca acaatagtcc gggcgtagat
    28801 gtaggccacc aagagggaaa tcagaaagga ggccagcaag gtatagggaa gaaactggag
    28861 actgatttgc tccgcttcct tttgtaaatc catggaagct agaaactgga gaatcatagt
    28921 accaccgtct tgcgttttca cctcgcgctc ctcaataaag agagaggttg tctggcggtc
    28981 tgtgtccaga ggaagactgt ccttgacttc taacttgtcc tcggtcatct cacctttgac
    29041 ggtccccttg atatcactag tctgggaata caagtctaac acttgctcga tactctgcct
    29101 atctttccct tctagggact gggcaatggc tgttgccttt tgaccaatgg tttcctgacg
    29161 atgactcaga taagtcgaag gaaaaagaaa ataaatagct aaatgaaggc agataaccag
    29221 aacactaaat atcgagaagg tatagataaa tatctttgca aataaacctg ttcgtttcat
    29281 tttcgctcca atttataacc aacattgcgc acagtgagga tacaatccaa gtctagcttt
    29341 ttccgcaatt ccttgatata aacatcaata acacggtcaa agggaacctc atctgtcgct
    29401 ttccagacgg catcgataat ctgagaccga gtcaaggccc ggccttcatt tttcactaga
    29461 tagtccagaa tttccaactc tttggcattg ataggcactt cttgacctgc gaggcttgca
    29521 ctgtagcttt caaagtccac cttggtatcc ttgtaagaaa agattcgtcc tgtatcgtag
    29581 tagcgcttga aaatcgcgtc caccctcact tttaaaaggg agagggagaa aggtttttcc
    29641 agatagccat ctgccaaaga ggcaaaggca ctcatcttgt attcctcatc ctgaaaagct
    29701 gtcaacatca agacaggaac ctgactggtt ttacgaatct cagctaggac ttctaagccg
    29761 ttaagcttgg gcatctggat atccagtaaa accagggcca cctcatagct agaaaattgc
    29821 tccagagctt cctgaccgtc cgctgcctca atagtttcat agccacaatc cgtcaaataa
    29881 tcactgaccc cctcacggat catctcttca tcttctacaa ttaaaatttt catactttaa
    29941 ctgctctcta ttttttattt ttcttagaat aaatacctac tctattttct attatagtct
    30001 cttgctggcc ttttgtctgt aagcaactga ccactagata aaacgttgtg aaattccttt
    30061 ctcataaatt ccataacttt agtatattat atttaagcac taaagtacaa agaaagcaac
    30121 tgaaagcaat gattttcacc actgctttcg gatttatttt taattgttaa atagccattc
    30181 ctatccacta ttcttgaata gaaacacaag atgcaatctt tattccagac tcattttttc
    30241 aaatttattc accatccagc aagagctctt ttggttgttt tctaaggaga ttgcttgaag
    30301 caagcgccat aacgagaacc actagaacca aggcaaggac aaaaatgatg ataaagtctg
    30361 atgtctgaat ggaaatgtct aggctcgaca aggtcttgct aaagccatct acttctgcac
    30421 caccaccaag gttagaggct tgagccgcct tactagcctg tttggcaaca cctgaagtca
    30481 cattggcaag gacagtgttt ccaattgcac gggcagtgta attagctagg aagtaagcag
    30541 aaactagagc agggatagca atcaagatag attcggtgat gaattgaccc aagatacttg
    30601 cctgcttgag gccgatagag aggagaattc ccacttcctt gcgacgggcg ttgatccaaa
    30661 ggctgagcaa gagggcaagg aggagaactg agaagctcaa gctaccccag aagaggaggt
    30721 tggccatctt gtacatacca gagatagatt gctcaagagc tgggtagtta gaggagctct
    30781 tgacgagtgt gtagctcttc cagttgatac cactgatgcc attcaactct ttcataacat
    30841 catccaagtt cttgtctgct gttacaaaga aggttgcgtc cccataaatg gctgtgtctt
    30901 ctgtgtatcc ataaagtttt gcagcagtgt gaatgtctgt aatagctgtg ttttcgtaaa
    30961 gttcttgtga gtaggttact gctgacttat tatgaccatc aaagagtccc ttgattgtca
    31021 cttcaactgt ttccttggct cctttttcat tatctgcatc gtagatatta gagtccagtt
    31081 taaccttgtc ccctactttc cagccgtgtt tggctgccaa gtccttgtgc aagaggattt
    31141 tatccttgtc gtcgttggtt aagtgctctc cttcgactag tttataagaa ccagagacaa
    31201 acttgtcttc tttagaggag tcattgacac ctgtaatcat caagctactt ccaaaacgtt
    31261 tggcacgatc agcagtgaga ttcttcttgg tttctggcgt ttcaatcagg tcatatccag
    31321 tcaaatctcc gatagcgttg atacgtttga cataagactc gatggccttg ttttcggtga
    31381 tttttttgat gtcttcaccc ttgatattcc cagcaccacg aggcgttcct tggttgacgc
    31441 gacgattgat ttgcatggag aagctattgg tgatattttt aaaggtctcc tgagaagcct
    31501 tggcagtagc tcccttgatt gacaagccga ccaaactcaa gctcgccatg aggagaataa
    31561 tcaggaagat gacaatcgat ttgaaaaact tccttgtaac ataggcaaat gcgttgtgta
    31621 acatagattc cctttctaga ttttgtttta atcattctat caaaataagc tcaaattatt
    31681 tactagtatt gcgcgtttca gtcagtttct tatcctttaa ttcaagtgta atatctgacg
    31741 cttgtgccac ttctttactg tgagttacga caatcacaca tttacctgtt ttctgggcaa
    31801 gtgatttgag tagttcgaca atatctccag cagttttagg atccagattt cctgttggct
    31861 catcagctag aataactgga gcttctgaga ccaaactgcg agcaatggca acacgttgct
    31921 gttgaccacc tgataactgg agaacattcc gcttgatctg gctttcatcc aaaccaagct
    31981 caagaagtgt attcttgctt gcctttttgt tgaccaagcg gatattttcc agcggagaaa
    32041 gataatctat caagttataa ttttgaaaga ccagggaaat atggtgcatg cgatggtaag
    32101 aatagccctt cttacgaata tcctctcctt gaaaaaggat agaaccttca acaggactat
    32161 ctagaccagc aagtagggac aagagtgtgg attttcctgc tcctgactcc ccaataatac
    32221 tgtaaaattt tccaggttca aaattataat cgatctgata taggactgct tcagcagtat
    32281 tcttataacg gtaggtaaca tcttgtaatt gtaataaagt catgatttct ccttcttaac
    32341 taatagatga taaaatttct ttcggtgatt ttctaaataa gaataggaaa caaagggcta
    32401 cagataagca actaagcaga actagaaaaa cataggattc tgcaaaagat aagatgctag
    32461 ttgataaact gcttgctttg gctagtgtat cttgtaagct tgcctgatct ccacttgcta
    32521 gtagagtttg gagtaggtaa gttgtgattc cgtttcctgc aacaaatgct ggaagcaaag
    32581 ctccaagaga taccaaaact acctctaaac agaattgtag gaagatcgag ctcttgcctt
    32641 ttccaagtgc aagtaaaatc cccacttcat agacccgttc tctcaaccag agagacaaaa
    32701 ccagaattaa ggctccagct cctgctatca acatcccata aaggaagatg gtcaggaagg
    32761 tttggaaagt tgcaactgag tctttgattt gttcaaaagc cttgttttcc ttttcgactt
    32821 ggtagccttg attttccaag gccaagtttt ctacctgctt catgagtccg tccatttcct
    32881 taggattttc tacatagaag cgtgctgcac tgacttgagc ttcactattg cccaaaaggg
    32941 tttggctact ttcatagtct gtaaagactt gattttcact gaagtcagaa gacaagcctg
    33001 tgaatttctc ttgtttttta ccagaaaaga tgccaataat ctcaaactct actgtttgtc
    33061 cttttccaga ttcagactga ccagcatcca agccaatctt gtcatgaagt gaaagaccgt
    33121 tcttcttagc caattcttcg tggataagga ttttcttgga atcccctttt tgaaggtgtc
    33181 gcccttcttt tagattgaaa gccgaactgg taaaggttac atccttggat gaatcctcaa
    33241 gagccgttaa gctaaccaag ttattgtctg cagctgataa atcatcacgc tccacgctct
    33301 gctcgccagt cactgcttcc ttgtctttta gttttgcgac cgtctcaagt tcaggagaga
    33361 cattttccag ccccttaatc ttgcttacag atgctaggtc tgacaacttg aatgtctgac
    33421 cattctctat cttcttaata gaaaaagatg tattgagtga tttataaaga ttgctttcta
    33481 ctgttttgtt ggacttcatc agagtcaaac aggctgaaat tccggccaat aagaccaata
    33541 aaatcagaaa taaaataaaa cttctcagtc gctttctgct gacataagcc caagatcttt
    33601 ggattggatt catttgtcac ctccatattt gtaagactat tataaaaccc aaatatgaaa
    33661 tgtttatgaa atacgaaaaa aaatatcgag taggggataa tctctagccc ctctcacacc
    33721 accgtacgtg ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg
    33781 taataatcca aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt
    33841 ttaagtaccg acttctgagc tactatagta gattgaaact agaataatat acctctactt
    33901 ctaaaatatt gttagaaatc gatttgactt ccctgatcga ttcgtcctat tcttatttca
    33961 ttttaatata attgatagtg gtcgccccag ccagatacct tatctgctat ccatttagga
    34021 acccctaact taagcaatcc ccataatcgt ctcgatttct tcttccattg cttccagata
    34081 atcactcgta ggcgagtacg caagcgctca tctatgctag tgactatact tttcatattt
    34141 ataattcatt cctttcgttt cactcaaggc acaacacaga atgaaaaagt gttgtgatct
    34201 ttattttgtt ttataataat agtgagaaag cctatcacta ctacaaatca cggggaggtg
    34261 aataagtgag tggtacagcc actacctcgc atattttgtc acatcattta acggtacata
    34321 ataagttgta ccatctgaat aagttgctac aatatcattt gcatgctctc cttcaccttt
    34381 agcaaaggtt ggagctcctg ctggatgatt tttatttgcc tctttcaatt tttcaataat
    34441 ggcatttttt tctgtatctt ttatattatc aggatttttc actaagattt tgtctggata
    34501 tgtcggttta gcagaaacaa tttttactgt tatttctttt ttattcgaag cacttgtcca
    34561 gtttccagca ttatctttaa tatttaattt tacagtaatt cctgaactag gaacttcagt
    34621 agcaggttga ttatcaacat tattcaactt taatttcaaa agagctgttg catcagacgt
    34681 tttatcaatc gttgtatata atgataaatt gttattataa ccagtttctt catatttagc
    34741 tgtttgtgag ctacttgaaa cagaactgaa attatgccca ctacctccct gattatcttc
    34801 aatgcttacg tctaaatgaa cttccccact attatttggc ttagcaacaa ctgttatagt
    34861 aaaataacat aaaatttgca taaatagatt agggaaatca aagcaacttc taggaatgtt
    34921 ttagcagtca cagtgtactt tcccagcatc aatccactat aactctgcac ataaaaatgg
    34981 ctctataata tttgtagtgg gtaaatcccc tatggatatt atggagccta tttttgtgta
    35041 gaaaaaaagt cccatatgac ctataatgaa aagcgacaaa acaa
//
LOCUS       DAVLBN010000019        33878 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLBN010000019 DAVLBN010000000
VERSION     DAVLBN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.019"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(93..329)
                     /locus_tag="VXC24_000891"
     CDS             complement(93..329)
                     /locus_tag="VXC24_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0493029.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(342..815)
                     /locus_tag="VXC24_000892"
     CDS             complement(342..815)
                     /locus_tag="VXC24_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493030.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(833..1018)
                     /gene="briC"
                     /locus_tag="VXC24_000893"
     CDS             complement(833..1018)
                     /gene="briC"
                     /locus_tag="VXC24_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0493031.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1177..1944)
                     /locus_tag="VXC24_000894"
     CDS             complement(1177..1944)
                     /locus_tag="VXC24_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0493032.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(1941..2807)
                     /locus_tag="VXC24_000895"
     CDS             complement(1941..2807)
                     /locus_tag="VXC24_000895"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0493033.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2844..4211)
                     /gene="accC"
                     /locus_tag="VXC24_000896"
     CDS             complement(2844..4211)
                     /gene="accC"
                     /locus_tag="VXC24_000896"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0493034.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4223..4645)
                     /gene="fabZ"
                     /locus_tag="VXC24_000897"
     CDS             complement(4223..4645)
                     /gene="fabZ"
                     /locus_tag="VXC24_000897"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0493035.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4642..5127)
                     /locus_tag="VXC24_000898"
     CDS             complement(4642..5127)
                     /locus_tag="VXC24_000898"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0493036.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5130..6365)
                     /gene="fabF"
                     /locus_tag="VXC24_000899"
     CDS             complement(5130..6365)
                     /gene="fabF"
                     /locus_tag="VXC24_000899"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0493037.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6387..7118)
                     /gene="fabG"
                     /locus_tag="VXC24_000900"
     CDS             complement(6387..7118)
                     /gene="fabG"
                     /locus_tag="VXC24_000900"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0493038.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7152..8072)
                     /gene="fabD"
                     /locus_tag="VXC24_000901"
     CDS             complement(7152..8072)
                     /gene="fabD"
                     /locus_tag="VXC24_000901"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0493039.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8065..9039)
                     /gene="fabK"
                     /locus_tag="VXC24_000902"
     CDS             complement(8065..9039)
                     /gene="fabK"
                     /locus_tag="VXC24_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0493040.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9158..9382)
                     /locus_tag="VXC24_000903"
     CDS             complement(9158..9382)
                     /locus_tag="VXC24_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0493041.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9442..10416)
                     /locus_tag="VXC24_000904"
     CDS             complement(9442..10416)
                     /locus_tag="VXC24_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0493042.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10416..10850)
                     /locus_tag="VXC24_000905"
     CDS             complement(10416..10850)
                     /locus_tag="VXC24_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0493043.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(10944..11729)
                     /locus_tag="VXC24_000906"
     CDS             complement(10944..11729)
                     /locus_tag="VXC24_000906"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0493044.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12098..13462
                     /locus_tag="VXC24_000907"
     CDS             12098..13462
                     /locus_tag="VXC24_000907"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0493045.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13465..13836
                     /locus_tag="VXC24_000908"
     CDS             13465..13836
                     /locus_tag="VXC24_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0493046.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14050..15324
                     /gene="serS"
                     /locus_tag="VXC24_000909"
     CDS             14050..15324
                     /gene="serS"
                     /locus_tag="VXC24_000909"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0493047.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15349..16248)
                     /locus_tag="VXC24_000910"
     CDS             complement(15349..16248)
                     /locus_tag="VXC24_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0493048.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16358..16906)
                     /locus_tag="VXC24_000911"
     CDS             complement(16358..16906)
                     /locus_tag="VXC24_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0493049.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17124..18446)
                     /locus_tag="VXC24_000912"
     CDS             complement(17124..18446)
                     /locus_tag="VXC24_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0493050.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18537..18625)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18789..21125)
                     /locus_tag="VXC24_000913"
     CDS             complement(18789..21125)
                     /locus_tag="VXC24_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0493051.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21229..21777)
                     /locus_tag="VXC24_000914"
     CDS             complement(21229..21777)
                     /locus_tag="VXC24_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0493052.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21774..22076)
                     /gene="zapA"
                     /locus_tag="VXC24_000915"
     CDS             complement(21774..22076)
                     /gene="zapA"
                     /locus_tag="VXC24_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0493053.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22163..23047
                     /locus_tag="VXC24_000916"
     CDS             22163..23047
                     /locus_tag="VXC24_000916"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0493054.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23059..23673
                     /gene="lepB"
                     /locus_tag="VXC24_000917"
     CDS             23059..23673
                     /gene="lepB"
                     /locus_tag="VXC24_000917"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0493055.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            23801..26167
                     /locus_tag="VXC24_000918"
     CDS             23801..26167
                     /locus_tag="VXC24_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0493056.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26215..27498)
                     /locus_tag="VXC24_000919"
     CDS             complement(26215..27498)
                     /locus_tag="VXC24_000919"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0493057.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28342..29478)
                     /locus_tag="VXC24_000920"
     CDS             complement(28342..29478)
                     /locus_tag="VXC24_000920"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0493058.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29540..29977)
                     /locus_tag="VXC24_000921"
     CDS             complement(29540..29977)
                     /locus_tag="VXC24_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0493059.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(29979..31934)
                     /locus_tag="VXC24_000922"
     CDS             complement(29979..31934)
                     /locus_tag="VXC24_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0493060.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(31958..33727)
                     /locus_tag="VXC24_000923"
     CDS             complement(31958..33727)
                     /locus_tag="VXC24_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0493061.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10054 a         7630 c         6390 g         9804 t
ORIGIN      
        1 ataggggatt tacccactac aaatattata gagccaacaa taaaaagaaa aagtgtttga
       61 tagatatcaa acactttttt ctttgcctcc cactatctaa aaaaatgata atagatataa
      121 ttgtaaacaa aaatccagat aggttttgca tgattgagaa agttaaaaaa actatggcag
      181 agaatcgtta atctcagatt gtcggtagaa cgataaacaa gggcaaaaaa gaaaccaatc
      241 agactataat ataataaact aattggatct ctgtgagata gtatcaaatg gctaatccca
      301 aagatgatag cagataggat aacatccaaa tagtacttgg actagggaaa gaaggtattc
      361 ataaaatacc ctctatcaag agtctcctca aaaacaggac cgatgattac aggcaggaca
      421 aaagataaga tagtcgataa aaaggttggt tgtccatttg aaaaaagcac ggtaaaatac
      481 tcatcatgaa tattcctatg attaatcaaa tgagcatagc gtgcccaaaa attaccgaga
      541 atctgataaa ccacataagt tgcaaataag tagaagacaa atgaccagtt ccagctcttt
      601 ttctcaaaga taaagagcat ctttttcttt tttaacctcc aaattaatag aaggaaactt
      661 cccactaatc ccattgttaa aataagagaa tagacatcag ctcctaaccc taaaatgatc
      721 gtcacataca atccaattgt ttgtggtaaa taggtagata gtaaaataat aagcaaaaat
      781 attccaaatt gtcttagttt ttttgtgttt ctcatcgtac ttttttgaaa gattaccctg
      841 ctcggaagcc gtacttccaa gcatctatat aagaattaag tgccccttgc ctcatatagg
      901 gagcaaattc tctataatat aaccatctac tatatccatc ttcccaaaca gcaagaccac
      961 ctgaagtttg ctccaagtcc tcagttgaaa gaactgtaaa tgtatttgta cctgtcattg
     1021 caagtacctt cttaaaatag attgttgtag gctcacattt atagtatatt tctttttttg
     1081 tctattttat agcccatctc ctcaactggc aatttttcga cctgaattac atttttccat
     1141 aaaaaatgag acctttctag tctcatttag tcattcttag tattttctaa atcgttgata
     1201 gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt ctagccagct ccgtttggag
     1261 ttcttttttg acactcttaa tcagttcttt actagaaagt cctatttcag aaatcacctt
     1321 atccaccacg tccatttcta acagttcatg cgaagtgatt ttcatcagtt ctgctgcttc
     1381 catggcgcga gtaccgtcct tccataaaat ggaagcaaag ccttctggac tgagaatggc
     1441 atagatagaa ttttccagca tccagacacg gtccgcgaca gctagagcca gagccccgcc
     1501 tgaaccacct tcaccgataa taatggcgat aataggaact ttcaggtcac tcatttccat
     1561 gagattgcga gcgatagctt ccccttgacc acgttcttcc gctccgacac caggataagc
     1621 acctgctgta ttgataaagg tcacaactgg acggccaaat ttctcagcat gtttcatcaa
     1681 ccgcagtgcc tttcggtagc cttctggatg tggttggcca aaattccgtt tgaggttgtc
     1741 ttgcaaactc ttgccttttt ggataccaac cactgttaca gcttgatctc caagccaacc
     1801 aataccacca acaactgcac catcatcacg aaaagaacgg tcaccatgta attggataaa
     1861 ttcatcaaaa atgcctgtcg caaagtccaa ggttgtcaag cgactctgct cacgcgcttc
     1921 tctgactatt tttgcaatat tcatctagga ctccctccat gcaatctgac taggctagca
     1981 atcgtatctg gtaagtctct tcttttgaca atagcatcca caaagccatg ttctaatagg
     2041 aattctgcct tttggaaatc ctcaggcaag ctttcacgaa ccgtattttc aatcacacga
     2101 cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa tgatatcgcc ttccatagcg
     2161 aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa tggtcaggta aaagagacca
     2221 gcatttgaat gacgtttaac cgccgcagag atcttagcca tctgcatgag actcatgatt
     2281 ccttcctgca tacgggctcc accagaggct gtgaatagga caactggcaa tttttcgaca
     2341 gtcgcatact caaacaaacg agtgattttt tcacctacaa ccgtacccat agaagccatg
     2401 ataaagttag aatccataat cccgagagcc acagtctgac ctttaataag agcagttcct
     2461 gtcacaacgg cttcatgcag acctgttttt tcacgcatag atgccagttt cttttggtaa
     2521 ccagggaaat gcaagggatc cttgctttca atccctgtaa acaattcttt gaaggttccc
     2581 atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac gaaaggtata gctacagtgc
     2641 ggacagatac gttcacttcc cagatccttc tgatagatgg tatgcttaca gcctggacac
     2701 tgggaaaata attcatctgg aacctctggc ttagcttgag gtttttccct aaccgaacga
     2761 ttgggattga ttcgaatata cttatctttt ttactaaata gagccattga ttcccctttt
     2821 cggtttaaac tcttaaagtc attttattct ttttcttgat atttaggtaa gaaggtttcc
     2881 atcaagaagg aagtatcata atccccagca atgacattgc gatctgaaat gaggtcaagc
     2941 tggaaatctg cattggtctg cactccttca atctctaatt catagagggc acgttgcatt
     3001 ttcatcaagg cgtcaaaacg attttcgccg tgtactatga ttttggcaat catactatca
     3061 taataaggcg gaatggtata acctggataa actgctgaat ccacgcgcaa gccaactcca
     3121 ccacttggca gatagagatt agtaatctta cctggacttg gagcaaagtt aaaggctggg
     3181 ttttctgcat tgatacgaca ctcgatggca tgaccgcgta ggacaatatc ttcttgctta
     3241 acagacaaag gctgacctgc cgcaatgcaa atctgttcct taacgatatc aacacctgaa
     3301 acaaactctg ttactggatg ttctacctga acacgagtat tcatctccat gaaatagaaa
     3361 ttgctacttg cttcatcaag aagaaattca atggttcctg cattctcata gccaacaaac
     3421 tctgccgctc gaacagcagc agcacctatt tcatgacgca gcgtttttcc gattgcaatc
     3481 gagggacttt cttccaaaac cttttggtta ttcctttgaa gagaacaatc ccgctcaccc
     3541 aagtgaatca catgtccatg ctcatcacct aggatttgaa cctcaatgtg ccgagctgga
     3601 tagataaccc gttctatgta catggcacca ttgccataat tggccttggc ctcactagag
     3661 gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa ccttacgaat ccctttacca
     3721 cctccacctg ctgaagcctt gagcataaca ggatagccaa ttttttcagc aacaatcaaa
     3781 gcttcttcag agttatgcac ttctccatct gaacctggta taacaggcac acctgcttta
     3841 atcatctgag cacgcgcatt gatcttatcc cccatcatat ccataacatg accagatgga
     3901 ccgataaact tgatacctac ttcttcacac atggtcgcaa atttggaatt ttcactgaga
     3961 aatccaaaac cagggtgaat agcttctgcc tcagtcaaga ctgcagctga tagaactgca
     4021 ttaatattga gataagactc tgttgccttg ccaggaccaa tacaaactgc ttcatctgcc
     4081 aaaagcgtat gaagagcttc cttatcagca gttgaataaa ccgctaccgt cgcaatcccc
     4141 aattcacgtg ccgcacggat aatacgaacc gcaatttcac cacgattggc aattaaaatt
     4201 tttcgaaaca tggagaacct ccttagttcc caattgcaaa agtaaggata ccactggctg
     4261 caagcttgcc atccacttca gcctttgctt caaccacagc tatggtgcca cgacgtttta
     4321 caaaagtcgc tgtcataacc aattggtcgc ctggtacaac ttgcttcttg aacttaacct
     4381 tgtccatacc agcgtaaaag accagttttc ctttattttc aggttttgat aactccaaca
     4441 caccagcagt ttgcgccaag gcttccataa tcagaacacc tggcataact gggtattgag
     4501 gaaagtggcc gttaaagaaa ggttcgttaa tggtcacatt tttgatagca acaatggtat
     4561 cctcgctcac ttccaagaca cggtccacta gaagcatagg ataacggtgg ggaagagctt
     4621 ctttgatttc ttgaatatcg atcatttgat acgtaccaat cctttaccaa actcaaccat
     4681 ttcttcgtta gagacgagaa tttccgttac cacaccatcc ttaggagctg ggatttcatt
     4741 catgactttc atggcttcga taattaccaa tgtttgacct tttttgacac tatcaccaac
     4801 tgtaacgaag gcaggtttat ctggtccagc agccaagtaa accactccaa caagtggact
     4861 ctctacaaga tttccctcag tagccacact tgcttcagct ggagctggaa cttcttctgc
     4921 tacagtctct gctggagcag atgtaggagc tactggactc ggtgttgcta gaacgggtgc
     4981 tggagcgact tgagttgcaa cttcaggcac aggtctcgct tcattcttgc taaactgcaa
     5041 ctcatccgtc ccatttttat aagaaaattc tctcaaactt gactggtcaa attgagtcat
     5101 caagtcttta atatcgttta aattcatact tatctattct cccaacgttt gaaagcaaga
     5161 actgcattgt ggcctccaaa accaaaagta tttgaaatag cgtatggaat ttctttctcc
     5221 aagccttgtc cataaacgac attagcttcg atataatctg atacttcact tgtcccagct
     5281 gtcattggta caaagttatg gcgcatagct tcgatggtga cgatagcttc tactgcaccc
     5341 gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg atacaggtac ttccttacca
     5401 agaacagcta cgatagctcc actttctcct ttttcattgg caggagttga cgttccgtga
     5461 gcattgacat aggctacttg ctctggagaa atctcagctt cttccaaggc tagtttgatg
     5521 gccttgatag ctccctgacc ttctggatgt ggagaagtca tgtggtaggc atcacaagta
     5581 tttccgtaac caaccacttc agccaggata gtagctccac gtttttcagc gtgttcaaga
     5641 ctttctaaaa ccaacatccc tgaaccttca cccataacaa acccattgcg atccttatca
     5701 aatgggatcg aagcacgagt tggatcctct gtagtagaga gagctgttaa ggcttggaaa
     5761 ccagcgatgg caaaaggtgt gatagaagct tctgttcctc ccaccaacat cacatcttgg
     5821 aaaccaaact taatggagcg gaaggcatcc ccaatcgcat catttgatga agagcaggca
     5881 gtattgatag atttacaaac accgtttgca ccaaaacgca tggctacatt cccagaagcc
     5941 atatttggta aagcttttgg aagagtcatt ggtttgacac gtttgggtcc tttttcatga
     6001 aggcgaagta cctgatcttc aatttccttg attccaccaa taccagatgc aacgataaca
     6061 ccaaaacgat ccctattaag agcctctaca tcaagattgg catgatttac agcctcttgg
     6121 gctgcataca aggcatataa agaatagtta tcaaaacggt tggtatcttt ttttacaaag
     6181 tatttatcga acggaaaatc ttggatttct gccgcattat gcacatcaaa gtcactatga
     6241 tcaaattttg taatgccacc aatgccgatt ttcccagttg ctaaactatt ccaaaattct
     6301 tctggtgtat ttccgattgg agatgttact ccataacctg ttaccactac tcgatttagt
     6361 ttcattcttt tcacctctag ctttcgctac atacttaagc caccatcaat ggcaatcact
     6421 tgaccagtta gataatcttg gcctgctaaa aatactgtca aatctgcaac ctgctctgcc
     6481 tgcccaaatt ctttcatcgg aatctgagct agtgtagctt ccttaatctt atctgataag
     6541 atagctgtca tatcagactc aatcattcct ggagcaatca cattgactcg tatattccga
     6601 ctagcgacct cgcgtgccac agacttggta aagccaatca agccagcctt agaagcagca
     6661 tagttagctt gaccaatatt ccccatcaaa ccaacaacac tagacatatt aatgatagca
     6721 ccttctctgg ctttcatcat cggtttcaag actgattgtg tcatattaaa ggcaccagtc
     6781 agattgacct tgagcacttt ttcaaaatct gcttctgtca tcttgagcat aagagtatct
     6841 tgggtaatcc ctgcattgtt gaccaaaaca tctactgaac ccagttctgc aatagcttga
     6901 tcaatcatac gcttagcgtc tgcaaaatct gatacatctc ctgaaatggg aaccaccttg
     6961 ataccatagt ttgaaaactc agcgagcaat tcttctgaga ttgccccacg actgtttaag
     7021 acaatgttgg ctcctgcttg agcaaacttg tgggcgatgg caagaccaat tccacgactc
     7081 gaacctgtaa taaagatatt tttatgttct agtttcattt ttttcctttc aaaacttcta
     7141 cttattttag tctatttttc taaaagtgct actaaactcg cttgatcttc cacatgagct
     7201 aagtgagcag tttgatcaat ttttttaaca aaacctgaca agactttccc cggtccaatc
     7261 tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa tactttcata gaaacgaacg
     7321 ggttccttga cctgacgcgt caagagctga gcaatgtcct ctttttgcat cacagcagct
     7381 tctgtattgc cgactagggg acaagtaaaa tctgaaaaac ttacctgagc tagagtttca
     7441 gctagtttct ggctagctgg ctcaaggaga gcggtgtgaa agggacctga caccttaaga
     7501 ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa ccgctcgatc aactgcaacc
     7561 acttctccag caatgacgat ttgtgcaggt gtgttatagt tggctggagt aaccactcca
     7621 agttcagaag ctttttgaca ggcttcttca atgacctcta ctggcgtatt gagaactgct
     7681 accatcttgc cagagtcagc aggagccgct tcttccatat aggctccacg cttagctacc
     7741 aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca ccaaggcaga gtattctcca
     7801 agagacaaac cagcaaccat atcaggctga tagccctttt cttgcaataa acggtagata
     7861 gcaaccgaag tcgctagaat ggctggttgc gtatagcggg tctgattgag tttgtcttct
     7921 tccgtatcga tgagataacg caaatcataa cctagcacct gactcgctcg atcaatcgtt
     7981 tctttaacaa tcggatactg atcatagaaa tcccgtccca tccctagata ctgggcacct
     8041 tgaccagcaa ataaaaaggc tgttttagtc atttcttaca actcctgtcc agcgagaggc
     8101 ttcttcttga attttcttag cggctccgta atacaaatct tttaggattt cttcagctgt
     8161 ttcttcttta gaaacaagcc ctgcgatttg acctgccatg acagagccac cctccacatc
     8221 accgtgaaca actgctttgg ctagggcacc ggctcccatt tgttcaaaga tttctaaatc
     8281 aggatcttcc tgcttaaagg catctttttc agccagttca aaatctctag tcaactgatt
     8341 tttaatagca cgaacagcat gaccaaagtg ctgagctgaa atcgtagtgt caatatccct
     8401 tgcttttaaa attttctcct tgtagtttgg atgggcattc gactcttttg caactacaaa
     8461 ccgtgtcccc acctgtacag cctctgcacc tagcataaag ccagccgcag caccttcacc
     8521 atccgcaatt cctcctgcag caataacagg aatagataca gctgtggcta cctgtcgcac
     8581 caaggtcatg gttgttaatt taccgatatg ccccccagct tccattcctt ctgcaataac
     8641 agcgtctgca ccgatttttt ccatgcgttt agctaaagcg acactaggaa cgacaggaat
     8701 aacgattatc ccagcttcat ggaaacgttc catatacttg cttggatttc ctgctcctgt
     8761 tgtgacaact ttaacacctt cttcaataac gagatccacg atatcttcca caaagggaga
     8821 taagagcatg atgttgaccc caaagggttt atcagtcaat gatttgattt tatcaatatt
     8881 ggccttgaca acttctttcg gggcatttcc cccaccgata attcctaatc ctccagcctt
     8941 ggaaacagcc cctgccaaat caccatcagc aacccaggcc atccctcctt ggaaaatagg
     9001 atagtcaatc ttcaataatt ctgtaatacg cgttttcata gtgcctccaa ccttccttgc
     9061 ttacgtaata gttcgatttc accataattt gacagtcaaa ctattaccta aacaagaggg
     9121 agtgggtttc tccctactcc ttctactaat attctgctta ttttgcttgc tcttcaacgt
     9181 aagcaaccaa gtcaccaact gttttcaagt cattttctgc ttcgatttgg atatcaaaag
     9241 catcttcgat ttctgagatt acttggaaca agtccaatga atctgcgtcc aaatcatcaa
     9301 aagttgattc aagtgttact tctgatgcgt cttttccaag ttcttcaacg ataatttctt
     9361 gtactttttc aaatactgcc atgataggac tcctttaaaa taaatagttt ttttataaca
     9421 atgtgttcac cacatgatta cctaaattgt aagaatgagc gtgccccagg tcaagcctcc
     9481 accgaagcct gatagaagaa cagtctggct accatctaaa gggatgagac cttgttctac
     9541 acactctgaa agtaaaatcg ggatactggc tgcactggta ttgccatatt ccatcatatt
     9601 ggctggaagt ttggctcggt caacaccaat ttttctagcc atcttatcca aaatacggtc
     9661 attggcttga tgaagtagca gataatccaa gtctgtcacc tctataggag attcatcaat
     9721 agtctgcttg atagacttgg ctacatctcg aatggcaaaa tcaaagactg tgcgtccatc
     9781 catcttcaaa aatgaatctg cactttcttg atctgaaaat ggagaatgca aacctgaatg
     9841 cccataagtt aaacactcgc tgcgacttcc atcgctattg agactctcag ctaagaaatg
     9901 ctcttgctcg ctagcttcta acaagacacc accagcacca tctccaaaca acacagctgt
     9961 tgatcgatcc gaccaatcga ctgccttaga gagggtttca ctaccaatca ccaagccttt
    10021 ttgaaagcga ccagaagcga taaacttttc agcagttgaa agagcaaata caaatccact
    10081 gcaagccgcg gttaagtcaa aagcaaaggc tttattagca ccaatattag cttgaacacg
    10141 agcagctgta gagggcatca tcgaatctgg agtaatggta gctaggatga taaaatccag
    10201 ttcttctcct gttattccag cttttgccat cagtttctta gcaacctctg tagccaaatc
    10261 actggtagat tctgttcttg aaatatgcct ttgtcgtatt cccgttcgac ttgaaatcca
    10321 ctcatcattg gtatccataa tctgagccaa gtcgtgattt gtaaccactt gctctggcac
    10381 ataatgagca acctgactta tttttgcaaa agccattatt tcaaatcctc caaaaattgg
    10441 taaagattag tcaagccttt acccatgaca gcaatttctt cctcgctcat gccatcaata
    10501 attttttcta ccatggcctt gtggaagcgt ttatgcagtc tatgaatcaa gcgacccttc
    10561 tttgtcaaat gcagatgcac cacacgacga tcctgttctg accgaactcg ctcaatgtag
    10621 cccttacgct ctaaattgtt caaacttgtc gtaacagttc caagagttac catcaactct
    10681 tttgacactt gacttggagt cacatctgga gccttaccga tgacatcaat cgtatgcatt
    10741 tctttgatgg agatatcctt aaaacgacta cctctcaagt tcacttcctc aattacaagg
    10801 acattgttaa atatagatgt taaatattca ttgattcgtt ggtagtccat ttttcatatc
    10861 cctccttctt caaaaaactt ttacaatcaa aacatttgac agaaagaatt atatcaaaat
    10921 tcaaagaatg atgcaagtat tttttatttt cctgtaaatt taggtcttct tctctccgaa
    10981 tgagctcgca ctccttcttt gaaatcctct gtttgagcta aggatttctg taggttcagt
    11041 tctaaagtag cgtaaccctg ccagtcttta aattggctct cccaaaccaa cttcttaatg
    11101 gcagcatagg aattacttga agcacgtctt aattttttaa gaagctgttc tctcgtcttt
    11161 tcaagttttt cagcttcaga aacgcggtaa accaaccccc attctagggc tttttctgcc
    11221 gttaaagcct ctcctgtcat agctaattga gcagcacgcg tcacaccgat actgcggctc
    11281 aagagatgaa ttccccctgc atctggagcc aaaccaacac caacaaaggc ttggataaac
    11341 ttagccttat ccgtcgccaa acagaaatct gccgcaacag ccatattcgc tgcggcacct
    11401 gcaacagcac cgtcaacttc cattaaaaca ggtttggcta tttgcttgat tttataagaa
    11461 atcgtattga ccaactctgc gatttttgtc aatgatggaa tatcatcctc atccactgcc
    11521 cgcttcatct ctaccaaatc tcccccaact gagaagacct tcccattggc attgattaag
    11581 ataaaatgca cagctggatt ttcttctgcc aaagtcagag cttctaaaat ctcctcacac
    11641 atgggaatat gaaaaccatt tgcgacctca ggacggttca aggtaaggat tgccaagtcc
    11701 tcttcaagct gataaataat gtgttccatc agggctcctt tttattttat aagcagttta
    11761 tactcttcga aaatctcttc aaaccgcgtc agcttccatc tgcaacctca aaacagtatt
    11821 ttgagctgac ttcgtcagtc ttatttacaa cctcaaagca gtgctttgag cagtctgcgg
    11881 ctagcttcct agtttgctct ttgatttcat tgagtgttaa attatttcac tgtcaaagta
    11941 tatctttttt aggagcagaa agcaagaaaa aatcgactga aagtgtctca gccgataaga
    12001 aaggctcgct ttaggctaga aagcatctta ttttcttcat tgaaaaaagc ctttctttct
    12061 gctataatcg tataaaatac ttactttagg agttcttatg aaagttgtta aatttggagg
    12121 tagttctctt gcctctgcta gtcaattaga aaaagtttta aacatcgtca aaagcgattc
    12181 agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc aatgctgaag atactaaggt
    12241 tacggatgcc ctgattaaat actaccgcga ctatgttgcg ggtaacgata ttagcaagag
    12301 ccaaagctgg attatcgacc gctatgctgc tatggttagt gaattgggac taaaaccagc
    12361 tgtgctagaa aaaatttcta aaagtattca cgccttggcc actcttccta ttgaagaaaa
    12421 tgaatttctc tacgatactt tcctagcagc cggtgaaaat aacaatgcca aattgattgc
    12481 tgcctacttt aaccaaaatg gtatcgatgc acgctatatg caccctagag aagctgggat
    12541 tgtggtcaca agtgaacctg gtcacgctcg catcattcca tcaagttatg acaagattga
    12601 agaattgaca aacaccaatg aagtccttgt cattcctggt ttctttggtg tcactaagga
    12661 aaatcaaatc tgtactttct cacgtggagg ttctgatatt acaggttcta tcattgctgc
    12721 tggtgtcaaa gctgacctct atgaaaactt tacggacgtt gatggtatct ttgcagccca
    12781 ccctggtatt atccaccaac cacactcgat tcctgagttg acctaccgtg aaatgcgcga
    12841 gttggcctat gcaggcttct cagtccttca tgacgaggct cttcttcctg cctaccgtgg
    12901 aaaaattcct ctggttatca agaataccaa caaccctgac catccaggta ctcgtatcgt
    12961 tctaaaacac agtaatgatg aatttccagt tgtgggaatt gctggtgact caggctttgt
    13021 cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct
    13081 gcaaatcctg gaagaactta acatcggttg ggaacatatg ccaacaggta tcgacgatct
    13141 ttctatcatt ctccgttctc gccaactaac tcccatcaag gaagaagaaa tcctgcgtca
    13201 gttggttcaa aaggctaaag tagatcatgc agaaatcgaa cacgaccttt ctatcattat
    13261 gattgttggt gaaaaaatga agagccacat cggagtgact gctactgcga cacgcgctct
    13321 atctgaaaac aaaatcaaca tccagatgat gtctcaaggt tctagtgaag tttctattat
    13381 gtttgttgtc aataaagacc aagagaaagc agcaattaaa gccctctaca atgccttttt
    13441 tggagaaagt aaggaagact aagcatggcc caatcactta acaaaacagt actcctcagt
    13501 acgacaggca cttcctacct ctctatcgct gggaaagttg ggaaattcct tgtcggagat
    13561 caggctttgg aattttaccc agatgtcaat gtcgaacaat ttatccagat tccttggagc
    13621 catatcaatc agattggagc caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc
    13681 tttacagaca aaggaaaatt cctctttgct tcaaaagact caggtgccat tctcaaaatt
    13741 gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt
    13801 agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac tttagtataa tcatagcaac
    13861 ggataagtag gttatcttct tctttcagaa agtctgcggg tactgcgagc agataggagg
    13921 gataggtgaa attctaccgt tagtaacaat tacatacaca atcaagtgca cacctgtgaa
    13981 gttggatgga accgtggccc tgccactcca acgttttgtc aggcgtgctt ttttcataaa
    14041 ggagttctta tgttagatat caaacgtatt cgtacagatt ttgaagctgt cgcagaaaaa
    14101 ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa tgaaagaaat cgatgctaaa
    14161 cgtcgtaaca tcttgattaa ggttgaaact ctcaaagcag aacgtaacac agtttctgct
    14221 gagattgccc aagctaagcg caacaaggaa aatacagatg acaagattgc tgccatgcaa
    14281 aatctatctg ctgaggttaa agccttggat gctgaattgg cagaaatcga tgctaaattg
    14341 acagaattta caacgactct tccaaatatc ccagctgaca gcgttcctgt tggggctgac
    14401 gaagacgaca atgtggaagt tcgccgttgg ggtactccac gcgagtttga cttcgaacct
    14461 aaagctcact gggatctcgg tgaagacctt ggtatccttg actgggaacg cggtggtaag
    14521 gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg ctcgtttgga acgtgctatc
    14581 tacaacttta tgttggatga acatggaaaa gaaggctata ctgaagtcat cacaccttac
    14641 atagtcaacc atgattctat gtttggtact ggtcagtatc caaaatttaa ggaagatact
    14701 tttgaactca gcgataccaa ctttgtcttg attccaactg ctgaagttcc tctgacaaac
    14761 tactaccgtg atgaaatctt agacggcaaa gatcttccaa tctacttcac tgccatgagt
    14821 ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata cgcgtggctt gatccgtttg
    14881 caccaattcc acaaggttga aatggtcaaa tttgccaaac cagaagaatc ttacgaagaa
    14941 ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa aactcaacct tccataccgt
    15001 gtcgttgctc tctctactgg agatatgggc ttctcagctg cgaagactta cgacttggaa
    15061 gtgtggattc cagcacaaaa caattaccgt gaaatctcaa gctgttcaaa cacagaagat
    15121 ttccaagccc gtcgtgccca aatccgttac cgtgatgaag cagatggcaa ggtgaaactc
    15181 cttcatacct tgaacggttc tggacttgca gttggacgta cagtggctgc aattcttgaa
    15241 aattaccaaa atgaagatgc ttctgtgacc atcccagaag cacttcgtcc atacatgggt
    15301 ggagctgaag tcatcaaacc ataaaaaata aggtttagct atttctagct agaccttttt
    15361 tcgtaaccaa atcagataag cacctagtac aaagaataaa atagttaggc atataatggt
    15421 ttcagccaat accaggtaat ccagaaatgg aagtttcaaa attccctgag ccatcttgag
    15481 cgaggtcgct gtgataatgg ttgggaaggt gagggctgag aaggctggtt gaaaaccttg
    15541 ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag aaggattgag aagccaaaat
    15601 catgacaatc aagacccaag tcggcaggct ggttcctcct actcgaacta gagaagccaa
    15661 gagtagagag aaaggagcac agtagattcc ttcttgtcca agcaaggcta gtgggagtgg
    15721 atgtttcttt aaatcgctat aaataagggg atagagatag aaggtcaaga gaaaaccaaa
    15781 actcaaggtc gcataggcaa tttcgataat acctaccaga ggataggtca aggcagccac
    15841 tgctatcccc acatagagaa ccgtccaact tggagtggca tgaaccctcc gccctggaca
    15901 agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc aagagaaatg aaaaccacca
    15961 aatcccttgt gctaccaaag gaagataaga gaatacgcga aagacatagg tcgataaaat
    16021 catcccagcc ataggaaagg ttgccattcc tgacaaaaga gggggcttgg tcaattcttg
    16081 cttggtttct ttccaattaa agagatgcag aattagaaag taaatccata aaaccaaacc
    16141 agtcagacta aaaagatggg atagaaccgg caacgtatct aaaataagat ttccagctcc
    16201 tgccaaacct agcaaacaac ctgaaaatac taaggggagt tttttcatcc taacctccaa
    16261 taatcatgtt agtttcagta taacataaaa gcgcttaaat gaggatttaa aaaaacgaag
    16321 tccgcttatt tcagacttca ttttactcag atatgaatta ggcataaggt tgcaattctg
    16381 gattaattgg tgtattagct aagttgttgg catagttaca gaggattgct aggctgacac
    16441 caaaaaccac atccaaggca ttttgttgag tgtagccagc ttctaaaaac tcagacaagg
    16501 cttcatctcc tacacgaccc ttggtattga taactgccaa ggtaaactta gctagggtat
    16561 ccaatttagg atctgtttca attggagtac gattgcgaag agcttgaatc aagtcatcat
    16621 tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc gacacagaag gcacaaccat
    16681 tggtcacggc tgccgtgatt tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac
    16741 ggtggataga tgagacaatt tgataggctt ctaaaacagt cggggcattg gccaagagac
    16801 cgattaggtt gggaatatag ccattgttgt ctttttctac tgtttcaaga atttctttca
    16861 cttctgctgg tgctgactct actgtatgga tagtaaatgt tgtcataaga tacctctttt
    16921 cttattattg acactaatat tattggaaaa tcttataaaa tcctgattcc taagtttatc
    16981 taagataaag ctttattctc tcataagatt ttcgttgtta tattagttta tcacacttcc
    17041 aatcacttgc ataatatata ttatatatca ggctgataaa aattatttat aggcaaaaaa
    17101 atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc agcaataacg
    17161 actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc gttaacgata
    17221 tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac catgagcaca
    17281 aaaaccacac ggtagagcca gataaagcga accccaaaga ggaactcaaa acagcgttct
    17341 ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gtacaaggaa gatggtcaag
    17401 agggcaggcc caaagtgtga aaagactgtt gagaaagctg actgagtcaa ggcaacccca
    17461 ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag agtacaaatg
    17521 atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac tggttcattt
    17581 gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    17641 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    17701 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    17761 atattaaaga aaataactgt aagagttcct aagatataaa tgatggccat aaaaggaaca
    17821 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    17881 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    17941 gcaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    18001 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatataatgc
    18061 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    18121 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    18181 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    18241 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    18301 ataaaaataa gctgaaaagc cttgggcaga cgcaaaacct gcaagagtcc tagccgaata
    18361 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    18421 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    18481 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    18541 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    18601 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    18661 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    18721 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    18781 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    18841 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    18901 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    18961 tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    19021 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    19081 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    19141 atcaagccaa cttgggcttc ccagcggccg tccttgagtt gactggtcaa ggtaccacgc
    19201 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    19261 ttttgaagga ccttgttttt agacaagtcc actttttcag gagccaattt tttcaacttg
    19321 gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    19381 atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc acgcgccttg
    19441 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    19501 atcttgagat tttcttgctc cacctcacgg atattgtcca agcgtttgcg gctttccagc
    19561 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    19621 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    19681 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    19741 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    19801 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    19861 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    19921 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    19981 aagctctgct caatagactg ctcatctcca atatcagcaa aaatttcttc aaaaatacca
    20041 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    20101 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    20161 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    20221 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    20281 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcatcatta
    20341 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    20401 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgg
    20461 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    20521 ttgcggtagg tgtttttgac tggtaaaacc ttacggccat ttctgctagc aacaattcct
    20581 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    20641 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    20701 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    20761 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    20821 agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    20881 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    20941 tgcggttgct cgacgaaaag agcctgcatt tccttcatct cagcaaaagc ctgtttgatt
    21001 ttatctgctt tggcagtcgg agccagttgt ctcaattgct ccaagccctg ctcggtcaac
    21061 aaatgaggct caaacaaggc cttgacctta tcgaactcta atgtttctaa tattttctta
    21121 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt aactttttac attctgatag
    21181 attcaagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    21241 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct ggatgatgtg
    21301 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    21361 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    21421 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    21481 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    21541 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    21601 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    21661 agccataaaa gccgatgcca tggctgaaat caggtaataa atctgtaaga gcaggcctct
    21721 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    21781 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    21841 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    21901 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    21961 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcactt
    22021 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    22081 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    22141 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    22201 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    22261 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    22321 tcagggtgaa ggggctgaaa aatacgccag tttctttggc tatcaagctg tagagcaaac
    22381 cagcggacaa aatcttcctt tgattgggac agatgaggta gggaatggtt cctactttgg
    22441 tgggcttgca gttgtggctt cctttgtcac acctgaccag catgccttct tacgaaaact
    22501 cggtgtggga gattctaaga ctctgaccga ccaaaagatt cgtcagattg ctcctattct
    22561 caaggaaaaa attcagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    22621 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    22681 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    22741 aaattatgac aagtacttgg cacaagagac caatcgtttc agcaatccta tcagcaatcc
    22801 tatcagctta gaagaaaagg ctgagggcaa atacttggct gtcgcagttt cttctgtcat
    22861 tgcgcgtgat ctctttctgg aaaatcttga aaatttggga cgagaactgg gttatcagct
    22921 tccaagtgga gctggaacgg cttctgacaa ggtggctagc cagattttgc aagcctatgg
    22981 tatgcaggga ctcaacttct gcgccaaatt gcactttaaa aatactgaaa aagcgaaaaa
    23041 cgcttagaaa ggtaagttat gaatttattt aaaaatttct taaaagagtg gggattattc
    23101 ctcctgattc tgtcattact agctttgagc cgtatctttt tttggagcaa tgttcgcgta
    23161 gaaggacatt ccatggatcc gaccctagcg gatggtgaaa tcctctttgt tgttaagcac
    23221 ctccctattg accgttttga tatcgtggtg gcccatgagg aagatggcaa taaggacatt
    23281 gtcaaacgtg tcatcggaat gcctggcgat accatccgtt acgaaaatga taaactttac
    23341 atcaatgaca aagaaacgga cgagccttat ctagcagact atatcaaacg cttcaaggat
    23401 gacaaactcc aaagcactta ctcaggcaag ggctttgaag gaaataaagg aactttcttt
    23461 agaagtatcg ctcaaaaagc ccaagccttc acagttgatg tcaactacaa caccaacttt
    23521 agctttactg ttccagaagg agaatacctt ctcctcggag atgaccgctt ggtttcgagc
    23581 gacagccgcc acgtaggtac cttcaaagca aaagatatca caggggaagc taaattccgc
    23641 ttctggccaa tcacccgtat cggaacattt taagagacct aagaggccga gaatcaccaa
    23701 tctcagcctc ttcttctatc gtgagaaaat gattggtaac tatctaaact taccagaaca
    23761 gaaacacctc aactctcacc tattcatgca aaggaatttt atggaagttt atttttcagg
    23821 aaccattgaa cggattattt ttgaaaatcc cagcaatttt tatcgcatcc tcctcctaga
    23881 aatcgacgat acggacgcag aggattttga tgattttgaa atcattgtca caggaaccat
    23941 ggctgatgta attgagggcg aagactatac tttttggggg caaattgtcc agcactccaa
    24001 gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca aaaccaacta gtaagggctt
    24061 ggtcaagtac ttttcaagta gccatttcaa ggggattggt ctcaagacag ctcagaaaat
    24121 cgtggatacc tatggcgaaa ataccattga cgaaattttg caacacccag aaaagttaga
    24181 aggcatcgca ggactctctg ccaaaaatcg cgaggctttc gtctccactc tccgtctcaa
    24241 ctacggaacg gagatggttt tggccaaact agccaactac ggcattccca acaaactagc
    24301 ctttcagatt caagactttt acaaggaaga aacccttgat gtggttgaaa attatcccta
    24361 ccagctggtt gaggatatca agggtttggg ctttaccatt gctgaccaac tagctgagga
    24421 actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc ggtctagttc acagtctttt
    24481 tcaggcctgt atggaaacag gggacaccta tgttgaagca cgggatttgc tggaacaaac
    24541 ccttactctc cttgagtctt cccgtcccgt ggaactagac cccagccaag ttgcccaaga
    24601 gctctcctac ctgatcgaag aagacaaggt tcagcagatt gataccaaga tctttgacaa
    24661 cagcctcttt ttcgctgagg aaggcatccg cagtcacttg gttcgtatcc ttgaaaaagg
    24721 aaaacagaag agtcatgatt taaaaaccat tcaaaaacat atcactacta tcgagaaaga
    24781 gcttggaatt gagtatgata acattcaaaa acaggctatc tgtgatgcta tccagaataa
    24841 ggtctttatc ctgacaggtg gacctggtac tggtaagaca actgttatca atgggatcat
    24901 cgctgtttac gccctgttag agggacttga cctcaggaag aaaagcaacc tgcccattct
    24961 tcttgctgct ccaactggtc gagctgctcg tcgcatgaat gaattgacag gtttgcctag
    25021 cgcgaccata caccgccact tgggaatgac aggtgacgat gataccagtc atctggaaga
    25081 ttacctagat gctgacttta tcatcgtgga tgaattctct atggtggata cttggctggc
    25141 caatcaactc ttctccagta tctcttctaa cagtaagatc ctcatcgtag gtgacagtga
    25201 tcagctacct tctgtcagtc ctggacaggt tctagcggat ctgcttcata ttcctttgat
    25261 tcctcagact cgcttggaaa aaatttatcg acaaagcgaa gaatcaacca tcgtcaccct
    25321 agctagtcag attcgacagg gcatcttgcc agctgatttc acccaaaaaa aagctgaccg
    25381 ttcctacttt gaaattgcta gtggccatat tcctgccacc attgaaaaaa tcttaggtgc
    25441 cgccctcaga aatggtattc ctgcccgtga tatccaagtt ctggctccta tgtaccgagg
    25501 gacggcaggg attgatgcta tcaatcagct catgcaagac ctgctcaatc ccccacaaaa
    25561 agatcaactc agttttgaag ctcctcagtg ccactatcgt aagggagaca aggtcattca
    25621 tttggttaac gatgctgaaa tcaatgtctt taatggggat ttaggagcta tcacagacct
    25681 gattcctggt aaatacaccg aatcgaaaca agacgagatt gtcattgatt ttgatggtaa
    25741 tgaagtctct tacccccgta acgaatggta caagattcgc ttggcctatg ccatgagtat
    25801 tcataagtct cagggaagtg agttcccagt tgtcatccta ccgattacta gtgctagccg
    25861 acgtatgctg gagcgaaatc tcatctacac agccattaca cgtgccaaaa gcaaactcat
    25921 cttactaggc gaattacaag ccttcgacta tgctacccaa cacatcggaa ctgcccgaaa
    25981 aacctatctg attgaacgct tcagtgatct actggagaat gttgaagaaa agcaacaagc
    26041 tgtctctgaa acagtcacat caagtgcctc tgaacaatcc tacatcctaa ccgaagaaaa
    26101 ctgggacagc attccagcca tgattgggat tacagacaca gacctcaaag agatttttgg
    26161 aaaatagtac atcagaaaac ccaccaattc aggtgggttt tctgtttatt aagattattt
    26221 tactgttgct gtgcttgtga tcaattcaac agcttttttg atagtgatat catgtttcaa
    26281 catgtcagct gaaagcaagt tttgaacttg tgcaacttcc atgttgtagt ctgctgccaa
    26341 ttgctcaact tctttttgga tttcttcttc tgaagcatca aatccttcag ctttggcaac
    26401 tgcttcgata acaaggttag tcttagtacg tgactcagct tctgcttggt attggttgtg
    26461 aaggtcttct tgagtagttc cagtgatttg gaagtacatg tcagggttga tcccttgacg
    26521 ttgcaagttc ccaaggaatt catttactga acggtgaact tcttcatgga tcatttcttc
    26581 tggaagttct acgatttcag cgttttctac agctgtatca attgctgcac cttcaactgc
    26641 atctttgtaa gcttcttctt tagcagcagc caattctttg cggtattttt ctttcaagtc
    26701 agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt tcatcgtcaa gagctggaac
    26761 ttctttagct tttacttcgt ggatagttgt cacgaattta gcttctttac ctgcaaggtc
    26821 ttctgcttgg tagtcttctg ggaatgttac gataacatca acggtttcgc cagctgagtg
    26881 acctaccaat tggtcttcga aaccagggat gaattgacct gaaccaagtc caagtgagaa
    26941 gttttcacct tttccaccgt caaattcaac accgtcgata gaaccaacga agtcgatcac
    27001 aacagtgtcg ccgttttcag cagcagcttc cttgataacc aattcagcca ggttgttgcg
    27061 ttcgcgttcg atacgctctt caacatcagc gtcagttact tctttttcta catcaactga
    27121 tacttcaagg tttttgtagt cacccaattt tacttcaggt tttgtaacga cttcagcagc
    27181 gataacccag tcttgacctt tttccattga agttacgtca atttttggtt gggcaaccac
    27241 ttcaagacca gcttctttta cagctgcttc ataagcgttt ggcaaaagag cgttcataac
    27301 gtcttggtaa agtgattctt caccaaattt tttatcgaag ataggacgtg gaaggtgacc
    27361 tttacggaaa cctggaacat taagagattt cttcactgac ttgaagacac ggtccaattc
    27421 tggtttgatt tggtcttgag agatagtgaa agtcaagaca ccacggtttg tttctttgtt
    27481 ttcaaatgat acagacattc tgtcatttct ccttaaaatt ttttaaatac agtctattat
    27541 aacattttct ataaataaaa tctagactaa tgcagccaat tatagacaac aagccttttt
    27601 cctaactaaa acactcataa agtatagaca attttagact actttggata tcttttggtt
    27661 agtcattttc caaaactaat ttatctaatt tttcagttat atagtagatt gaaactagaa
    27721 tagtacacct ctacttctaa aacattttta gaaatcgctt tgactgtcct gatcgatttg
    27781 tcctgttctt gtttcatttt actatataga tcgcattcga aagaattcgt tccaaaattg
    27841 cttggttcgt tcttctcttg gacgactaaa gaattgatgg gcattatttt tttcaacaat
    27901 tttcccaccg tccataaaaa taacatgatg ggctacatct ctagcaaaac ctatctcata
    27961 aagctgatca aaaactcaat ctgaggagaa aatccaataa ggctttccat aataaaggac
    28021 atcctatcaa gatttttgaa cacccgatag gctgcctttt tccgattttg aagacttttt
    28081 gtccagcttc ttttacctta taaataacaa caaaaatcaa agacaagcta gaaagattac
    28141 cgcagataac tcaaacagtg ttttgaggtt gcagataaga ctgacggagt cagctcaaag
    28201 cactgctttg aggttgcaga taagactgac ggagtcagct caaagcactg ctttgaggtt
    28261 gtagatagaa ctgacgaagt cagtaacata tgcctaagac aaagcgatgc taacctgatt
    28321 tgaagagatt ttcgaaaaat attaaatata ctctacaatt tgctcaatca attcttggtc
    28381 gtctaaacct gtaacttgta taacaacatc tttgactgat tgtttagcca acaattcacc
    28441 taatcgaata ctttcttcat catttacatc gcgatagtca aaggcatagc caactgtttt
    28501 aagtaggttt ttatatgaca aactgagttc tttcaattca cgtatcggcc ggatgaatcg
    28561 ttcattatag cctaattttc ggattggagt acgagctacg cgactaacct cgtccactat
    28621 gaaagggttt tcaaaccgtt ctataatgac tttgtgataa ttctccaatt cttttttatc
    28681 aaagttccat ttggcaatca agagactccg aatttcagct aatacagatt caatccgaga
    28741 tttaatatta ggattttgaa gagcttccaa aattgtcttg gcaccataat gcgcaccaat
    28801 gtaagctgaa gttgcatgtc cagaattgac tgaaaaaagt tttcgctcaa taaagggttc
    28861 taaatcttct tcataatgca catcttttag acgtaaatct ggatttttaa gacgcttggt
    28921 ttccacgacc cattcattaa agggctcgac cacaacaaaa agggaatctt cgtgactttg
    28981 tgctggaaca atcctgtcta ctgcagcatt tggaaaacct atgtagttat cagcaaatgt
    29041 caaaccttcc ggacttaaat atttcttgac ttcttgataa agaaattgag acccgccaat
    29101 catattttca caggccataa catccaatac ctgtgtattc cctgcaactc ggcgagcttc
    29161 gattcctttg gctagaagtt cagcgataaa agggagtata ttaggtccga ttgcagtagt
    29221 aataatatcc gtcttttgaa tcgcttcaat gacttgctca ggatgttctt tgctattaat
    29281 tccagccaca ttagttactt ctatacgaga ctgtcctttc tgtgcaattt caatttcata
    29341 cttgcccttt tcatttagag catgaattat ctgattattg acatccacaa aatcaatatg
    29401 gaaaccattt ttaaatagaa tttcacctat aaaaccacga ccgatattac cggcaccaaa
    29461 atgaacagaa tgtttcattc aatttctcct tttcctattt gagggacata tatactagat
    29521 ggcaaatgac gaaattcaat tattcaacag catcaaataa gcgcaatact tcctcttttg
    29581 actgagcatc ggctaattta agaacattat ctacatctgc acagaagata gaaattttct
    29641 gaataatttc taagtgttca ttaccaatac cagcaatacc aaaaagaacc gttgccactt
    29701 gagggttaga tacattccca aaatcaaccc ctctagggac ttgaacgact gtaataccag
    29761 acttgaggac atcctttttt gctgcatctg ttccatgcgg tattgcgata aagttaccca
    29821 tgtaaacaga tagctcttta tctcgctcaa tcatggcttc aatatagtct tcattaacat
    29881 atccaccctc ataaagaact tgcccacaat aacaaatagc ttcctccttg ttagaaaatt
    29941 gtttattaag cttaatcaaa tgtttttcaa gtttcatatt agttctccaa tttcttaatt
    30001 ttttcgttaa aaatagtatt tagcatctga taaataatgg attgatttcc cgtcttgtaa
    30061 atctctgtat aaagatgatt ttcaataatc gactgactaa tagctgtcat taaatctctc
    30121 gcttcctcgc tagcttcttt agacattagc attagcagac accttttgac ctcttcttcc
    30181 tctcgtttca ttgacaatgc ggagataggt agtttgagtt caaacatagt aaaactattt
    30241 gttgttactt tgctagactg actatgtaaa agcaccagac cagtattagg aatagccata
    30301 ggactattct ggaagtgaga taacaatttt cttgttaggt aatctctgtc actcacattc
    30361 ttctgatatt ggatgatttg ttctaccgtg tgctcaaatg attgattatt ctccaattga
    30421 accaactcga attgactcaa aagctgacta ctagatatta aataatcttg caagtcataa
    30481 cttttctctg gagcgatagc atcacgcgcg acaattgtac gatgtgcctg tacatactga
    30541 agtcgttcct gtaattcaag caattctttg acggttggaa aactagaaat tacatcgatt
    30601 tcctgattag tcagcggctt ggtagataaa atataatcat actgactgag atcaatactg
    30661 tggtaatcta ctagagactg aatatctatc aactctacaa aaggagcaac actcttaatt
    30721 ttactgacta ataaatctct agtgacccga cgttcatccg ttaaaagcaa aacacggact
    30781 ggataaatct ctggactacg gcctaagcta gagataaaat gtagggcaat catgccatac
    30841 tcatactctg tatgaagata tttcggaaaa atatcattca ctaaaagact gatgactgta
    30901 taaagaaatt tattcctttc aactaaaatc tggacagatt ctggcaaatt ttcaccctga
    30961 aaaaggatag ggacgcctaa actgagccga atatgatgga aaagaaaatt gaataaaacc
    31021 ttgtccttaa aaaagtcaat cttggtatac atggaaaccg tatcaatcag atttgaaata
    31081 ttgtagaaaa attcaccatc aaatttctcc gtaaagagcg gattgtcctg acgtttaatg
    31141 attaattcat ccaagatgct cgcaaaatag ataatttcct gaatactata aaattgtgca
    31201 gtctgcttag agtaagcttg aaaaattttt tgagaaattt ccaaagcctg cttactagta
    31261 ttaggtgaat tttcaatgtt ttgctcctga cctataagag ataacaagat cgcaaaaaac
    31321 atcttcatcc tagcatccat atctggaaaa cctgacagtt gcttattaac aatctgactg
    31381 gccagcctag ttctatctgc ttctaaaata tcaaagctcc caaaattacc ggttgaaaaa
    31441 tctgctactg agatacagtt tgtcagtaaa atagccaaaa atcttctctt accaactgaa
    31501 tcaccagaaa tccgataacc tttttgtcgt tcaattttca gatcaaagtc taaaagacgc
    31561 ttatcaatat ctgaaatatc ctgaataata gttacattac tgactttcgt gcactcttgc
    31621 aatgcttcat tggtgacaaa accactctca gtcagaaggc gataggtaat caactcttgt
    31681 ctttcttggg gactatactc aactaacact tcaagttctg tcggcaaatc atccaactct
    31741 ccagtcaaaa tatagtattt cccatgcttc gttatttcga ttccatattg ctccatgcta
    31801 tctgtcaaat ctgataaagt tcgataaatt gttctagatg aaacctgtaa gatttcagtc
    31861 atatcttgca ttgaaagctt ccctacatgt aggaaagcct tcaataattg ttcttctcgt
    31921 ttggttaata gcattcgtaa tttagaaacc tctagttcta tttgtacatt ctagcagcca
    31981 ttttgtcata ttctggtgtt gttactaaac tatccacaat aagaaattga gaattcggtg
    32041 ctgcttgctg cacttctgcc tgtaaagaaa tagttgttac aatcattatg tttttagaat
    32101 taaattcacc taattctgaa attttggcag tagaaactgg aatacgaata ttcttgtttc
    32161 taaagatagc ccgaatcgtt tcacagccca tagttgcagt tccctgtgct ttaccataag
    32221 caactactac agcatcaata tggttaaggt caatttcctg actatctact ggtgctgaag
    32281 ttggtatatc tccttcaatt tctgctattg gaaaagctcc tgttaatgaa gctacaattt
    32341 catcataacg aggggacgct aagaaattat caacagaaac atgaatagca cttggactct
    32401 tgtctttagc tcttggtgtc agttcttcct gagtaacaat taatgttttt ggtgtatcaa
    32461 gcaaatttga gattgcctga ttagatactg gaatctctag acctgctttt ttaaccttat
    32521 ctcgaagaat actagctccc atagcagagc ttcccatacc agcatcgcag gcgaaaatga
    32581 ttttttccac tgagtctgtc gaaataactg catcaacaga agttgatact aactgacctt
    32641 tagactgagc tttagctgct tgggtagcct cttgagcagc ttcgagcgaa tcctcagttg
    32701 acttgtctgc atgaagaata agggctgcta caaagaaaga aacaactgct gccactaaaa
    32761 cacctagaag aacatttaga tggggccaaa caccttttgg cgccgtagcc ataatcgcaa
    32821 taatagaacc tggtgaagct ggagatttaa gaccagcgtc taagagttga aaagtaaaag
    32881 ttccagagat acctcctgcc atagcagcta aaaatagagt aggcttcatc ataacataag
    32941 gaaagtaaat ttcatgaatc cctccgaaga aatgaataac cattgccccc caagaagaag
    33001 atttagcaga acctttaccg aatacagcat aagctaatag aattcccagg cctggtccag
    33061 gattagcttc caataggaag agaattgact taccagcttg agctacctgt tctactccca
    33121 gaggagtaaa aatgccatga ttgagggcat tattgaggaa aaggacttta gccggttcga
    33181 tgataatatt agctatagga aggaggcgag cattgacaat agcctcaaca ccattcccaa
    33241 cagctccagt aagagtcgat acgactggac cgattgcgta gaaagccaaa agcaataatg
    33301 caaaaccaac gagaccagct gagaagttat taactaacat ttcaaatccg ggacgaattt
    33361 tttcctggaa cttctcatca aatttcttga tagtccatcc tcccagtggg cccattacca
    33421 tagctccgat aaacatagga acactagaac ctgtgattgc accaacagta gcaatagctc
    33481 ctacaacggc accacgttgg ccatggatca tatatccacc tgtgtaacca atcaggattg
    33541 gcaataaata cgttaacata ggaccaacaa cagtagctaa ctgttcattt ggcagatagc
    33601 catcagcgat aaagagggca gtcaatactc cccaagcaat aaatgctcca atattgggca
    33661 taaccatatt tgaaagcgat gtccctagtt tttgaaccct gactttcaat gatacttttt
    33721 cttccattag atcatcctcc ttttcttaaa actagtatat acaaagttaa aaacctttaa
    33781 aactaaagtt ttgtcacaaa ttttgtgtca aaacattact tttgacgagg ctgggcaaaa
    33841 aggcttaaaa atgataaaac gcatcatatc cggtgtac
//
LOCUS       DAVLBN010000020        33793 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLBN010000020 DAVLBN010000000
VERSION     DAVLBN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.020"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            83..880
                     /locus_tag="VXC24_000924"
     CDS             83..880
                     /locus_tag="VXC24_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0493062.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VXC24_000925"
     CDS             1028..1150
                     /locus_tag="VXC24_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV0493063.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            1172..2287
                     /locus_tag="VXC24_000926"
     CDS             1172..2287
                     /locus_tag="VXC24_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0493064.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            2383..3657
                     /locus_tag="VXC24_000927"
     CDS             2383..3657
                     /locus_tag="VXC24_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0493065.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VXC24_000928"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VXC24_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0493066.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VXC24_000929"
     CDS             4786..5088
                     /locus_tag="VXC24_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0493067.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VXC24_000930"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VXC24_000930"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0493068.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VXC24_000931"
     CDS             5962..7302
                     /locus_tag="VXC24_000931"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0493069.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VXC24_000932"
     CDS             7280..7492
                     /locus_tag="VXC24_000932"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0493070.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VXC24_000933"
     CDS             7489..8364
                     /locus_tag="VXC24_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0493071.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VXC24_000934"
     CDS             8357..9172
                     /locus_tag="VXC24_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0493072.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VXC24_000935"
     CDS             9165..9596
                     /locus_tag="VXC24_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0493073.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VXC24_000936"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VXC24_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0493074.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VXC24_000937"
     CDS             11272..12000
                     /locus_tag="VXC24_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0493075.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VXC24_000938"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VXC24_000938"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0493076.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTAQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14196..14276)
                     /locus_tag="VXC24_000939"
                     /pseudo
     CDS             complement(14196..14276)
                     /locus_tag="VXC24_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14450..14925
                     /locus_tag="VXC24_000940"
                     /pseudo
     CDS             14450..14925
                     /locus_tag="VXC24_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14963..15265
                     /locus_tag="VXC24_000941"
     CDS             14963..15265
                     /locus_tag="VXC24_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0493077.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            15273..16074
                     /locus_tag="VXC24_000942"
                     /pseudo
     CDS             15273..16074
                     /locus_tag="VXC24_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16123..16587
                     /locus_tag="VXC24_000943"
     CDS             16123..16587
                     /locus_tag="VXC24_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0493078.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            16744..17169
                     /gene="lacA"
                     /locus_tag="VXC24_000944"
     CDS             16744..17169
                     /gene="lacA"
                     /locus_tag="VXC24_000944"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0493079.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            17200..17715
                     /gene="lacB"
                     /locus_tag="VXC24_000945"
     CDS             17200..17715
                     /gene="lacB"
                     /locus_tag="VXC24_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0493080.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            17726..18655
                     /locus_tag="VXC24_000946"
     CDS             17726..18655
                     /locus_tag="VXC24_000946"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0493081.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            18657..19637
                     /gene="lacD"
                     /locus_tag="VXC24_000947"
     CDS             18657..19637
                     /gene="lacD"
                     /locus_tag="VXC24_000947"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0493082.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            19871..20707
                     /locus_tag="VXC24_000948"
     CDS             19871..20707
                     /locus_tag="VXC24_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0493083.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            20743..21060
                     /locus_tag="VXC24_000949"
     CDS             20743..21060
                     /locus_tag="VXC24_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0493084.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            21062..22756
                     /locus_tag="VXC24_000950"
     CDS             21062..22756
                     /locus_tag="VXC24_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0493085.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            22965..24371
                     /gene="lacG"
                     /locus_tag="VXC24_000951"
     CDS             22965..24371
                     /gene="lacG"
                     /locus_tag="VXC24_000951"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0493086.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            24461..24673
                     /locus_tag="VXC24_000952"
     CDS             24461..24673
                     /locus_tag="VXC24_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0493087.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(24952..25713)
                     /locus_tag="VXC24_000953"
     CDS             complement(24952..25713)
                     /locus_tag="VXC24_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0493088.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(26001..26963)
                     /gene="nrdF"
                     /locus_tag="VXC24_000954"
     CDS             complement(26001..26963)
                     /gene="nrdF"
                     /locus_tag="VXC24_000954"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0493089.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(27151..29310)
                     /gene="nrdE"
                     /locus_tag="VXC24_000955"
     CDS             complement(27151..29310)
                     /gene="nrdE"
                     /locus_tag="VXC24_000955"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0493090.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(29391..29609)
                     /gene="nrdH"
                     /locus_tag="VXC24_000956"
     CDS             complement(29391..29609)
                     /gene="nrdH"
                     /locus_tag="VXC24_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0493091.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            29960..30223
                     /locus_tag="VXC24_000957"
     CDS             29960..30223
                     /locus_tag="VXC24_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0493092.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            30229..31962
                     /gene="ptsP"
                     /locus_tag="VXC24_000958"
     CDS             30229..31962
                     /gene="ptsP"
                     /locus_tag="VXC24_000958"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0493093.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            32217..>33793
                     /locus_tag="VXC24_000959"
     CDS             32217..>33793
                     /locus_tag="VXC24_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0493094.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT        10431 a         6074 c         7401 g         9887 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatgatttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 attcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggat ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 gactccagct actgagtctc gtgcagtgcc gatttatcaa acaacatctt ttgtttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatattga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatattc gtgatgtggg tgcagcaacc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa actctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaacc aaattcgtct
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgacc
     3541 acatctgaaa accaactccg tttagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgaagact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctctctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac gtacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctgat gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggaacctcaa gatgtcttta
     5521 tcgttgaggg tattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttagagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgctttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttgggac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgtta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgtac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ccatgaatga catggaaagt gtcgaagagt
    10381 atgaccctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg cacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggct
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct
    14161 acaacctcaa aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaactg
    14221 tgttttgagt aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag
    14281 aacagaaaaa tgcttggagt atttgtttgt gtgtttattt ttatataaca aactataaac
    14341 acaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa gtaattaaca acgatttcat
    14401 atagtgttat acttatagca taaagttaat ggaaagaagg gaaaacctta tggtattaga
    14461 ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg gataatcaag aataactctt
    14521 tgatcaggta gcaagcttgt tggaggaacg agaaattgta actccaactt atcgtgaagc
    14581 tttgatcacg cgtgaaaagt catttccaac tggtttagat atggaatttc taggaaagga
    14641 cttgcaaatg taatgattcc tcacacagat attgttcata atctagctga gaaagtggtg
    14701 gttgttcgat tagagaaacc ggtgactttc cataatatga ttgcgccagg taaggaagta
    14761 gaagtatcct tgctcttctt tatcatcaat aattcaagtt caagtcaaac gaacattctt
    14821 gctcagttga tggacttttt cacaggaaat ggacatcttg aagacctatc aaaaatttcc
    14881 gaaccagaaa aactttatgc ttatatagat gaagcaatcg cttaatcttg tctattaaaa
    14941 aataaaatcg gaggaagtct atatgattaa aattcttgct gcctgcggtg caggtgttaa
    15001 ctcaagtcac caaattaaaa gtgctctaga agaagaactt tcaaaccgtg gttacgatgt
    15061 tcactgtgat gcagttatgg tgaaagatgt aaacgaagac cttatgaaag gttacgatat
    15121 ctttacacca atcgctgcaa cagaccttgg ttttgaacca ggtatcccag ttatcgaagc
    15181 tgggccaatc ttattccgta tcccagcaat gagcgttcca gtatttgaca atattagact
    15241 tcctgcgaaa caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa
    15301 ctgatgcacg atttaagcgt cttgttggtg ttcagcgtac cacttttgaa gagatgttag
    15361 ctgtattaaa aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa
    15421 gcctagaaga ccttcttatg gccactcttc aatagtgcga gaatatcgaa cttatgaaca
    15481 aattgcggct gattttggta ttcacgaaag caactttatc cgtcggagcc aatgggttga
    15541 agtaactctt gttcaaagtg gtgttacggt ttcaagaact cctctcagct ctgaggacac
    15601 ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaagaat tagcgaatga
    15661 ttctggtaaa aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag
    15721 attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
    15781 cgcagaaata tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg
    15841 aagatatatc ctcaagtaca aactccacgt aaatccagca aactcaagcc gctaacagtt
    15901 gaagataaaa cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt
    15961 gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc
    16021 ggattacgaa tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc
    16081 aggaagtcta ataaagaaac tagcaaggtc aggccttact ttattggtgg acatccagga
    16141 tttaattgtc ctctacttga tgatgaagtc tatgaagatt attatctaga gtttgagaaa
    16201 gaagagactt gctctgttcc acgtcctttc ccagaaacag gtatgttgga tttccaagat
    16261 agaagtccat ggctagaggg acaaaaagaa atagatctta gttatgatct tttcagcaaa
    16321 gatgcagtga ctttggatga attgcaatct cgaacaattg cccttcgttc tcttaaacat
    16381 gataggggat tgaaagtgca ttttgcagaa tttccaaacc tcatcatctg gtcaactttg
    16441 aacaagggac ctttcattac ctttgaacca tggtctggct tgtcaacatt ccttgaagaa
    16501 ggagatcatt tagaagataa gaagaatgtt tgtctcttag aagccaatca ggttgaagaa
    16561 ttagggtttg agatagaagt tttataaaaa agtaaaaaat aaataacaaa aacaaacaca
    16621 aactgttgac ttcttcaaac aatagtagta tattatgttt gtgaggacta attgactgtt
    16681 ttttaaagac agccaataca ctgctggaat ccagcataga aaaaataaaa aggagtatac
    16741 aatatgtcta ttgttatcgg tgcagatgct gcaggtttga gattgaaaga agttgtgaaa
    16801 gacttcttag aaaaagaaaa cttccacctt gtggatgtta cagctgaagg tcaagacttt
    16861 gttgatgtga ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc
    16921 gtgattgatg cttatggagc tggtccattt atggttgcaa ctaagatcaa aggaatggtt
    16981 gctgcagaag tttctgatga acgttcagct tatatgactc gtggccacaa caactcacgt
    17041 atgatcacta tgggtgcaca acttgttggt gatgaattgg ctaaaaacat cgctaaagga
    17101 tttgttaatg gtaaatacga cggtggtcgt caccaaatcc gggttgacat gttgaacaaa
    17161 atgggctaat tagattatag taagaaaggt aagttaaaaa tgagaattgc aattggatgt
    17221 gaccacatcg taacagatga aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat
    17281 gaagtcattg actttggtac atatgaccat acacgtactc actacccaat ctttggtaaa
    17341 aaagtagggg aagctgtaac tagcggtcaa gctgatcttg gagtatgtat ctgtggtact
    17401 ggtgttggta tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt
    17461 gatatgacaa cagcccttta tgctaaagaa caattgaacg ctaacgttat tggttttggt
    17521 ggtaaaatta ctggtgaatt gcttatgtgt gatatcatcg aagctttcat ccatgctgaa
    17581 tacaaaccaa ctgaagaaaa caaaaaattg attgcgaaaa ttgaacatgt tgaaagtcac
    17641 aatgctcaac aaacagacgc aaacttcttc actgaattcc ttgaaaaatg ggatcgcgga
    17701 gaataccacg actaagaggt aacctatgat tttaacagtt acaatgaacc catccattga
    17761 tatttcctat cccttggatg agttgaagat tgatactgtc aatcgtgtgg tggatgtaac
    17821 caaaacggct ggtggtaagg gactcaatgt tacccgagta ctttcagaat ttggcgattc
    17881 tgttcttgct actggtttag tgggtggcaa acttggtgag tttttggttg aacatatcga
    17941 taatcaagta aagaaagatt tcttctcaat tcagggagaa actcgtaact gtatcgctat
    18001 tctccacgga gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat tggaacagga
    18061 aggtcaagac tttttggaac atttcaaaaa actcttggag tcagttgaag tagtggccat
    18121 ctcaggtagt ctgccagctg gccttccagt tgattactat gcgagcttgg tagaacttgc
    18181 taatcaagct ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc aggctgttct
    18241 tgaatcaccc cataaaccaa cagtcatcaa accaaataat gaagaattgt ctcagcttct
    18301 tggaagagaa gtttctgagg atttggatga attaaaagaa gtacttcaag aacctttgtt
    18361 tgcagggatt gaatggatta tcgtttcact tggtgccaac ggtacttttg ccaaacatgg
    18421 tgacactttc tacaaggtag atattcctag aattcaggtg gtaaatcctg ttggatctgg
    18481 agactctact gtggcaggaa tttcttcagg acttcttcac aaagaatcgg atgcagaatt
    18541 actcatcaag gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt
    18601 caacatggcc aactatcaag ttctatatga tcaattaata gtaaaagagg tataaaatgg
    18661 ctttaacaga acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat ggtatcatct
    18721 cagctcttgc atttgaccaa cgtggtgctt tgaaacgcct catggctcaa caccaaacag
    18781 aagaaccaac tgtggcccaa atggaagaac ttaaagtctt ggtagcagat gaattgacta
    18841 aatacgcttc atctatgctt cttgaccctg agtatggact tccagcaact aaagctcttg
    18901 atgaaaaagc tggtcttctc cttgcttatg aaaaaacagg ttatgacaca acaagcacaa
    18961 aacgcttgcc agactgcttg gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag
    19021 atgcagttaa attcttgctt tactatgatg tagatagctc agacgaactc aatcaagaaa
    19081 aacaagccta catcgaacgc atcggttctg agtgtgtggc tgaagatatc ccattcttcc
    19141 ttgaaattct tgcttacgat gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag
    19201 taaaaccaca caaagttatc ggcgctatga aagtcttttc agacccacgc tttaacattg
    19261 atgtcttgaa agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg
    19321 aagtagttta tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat gaagcaacga
    19381 acttgccata catctacttg agtgctggtg tatcagctaa actcttccaa gatactcttg
    19441 tatttgctca tgaatcaggt gcaaacttta acggagttct ttgtggccgt gcaacatggg
    19501 ctggatcagt tgaagcatac atcaaagatg gtgaaacagc agctcgcgaa tggcttcgca
    19561 caactggatt tgaaaacatt gatgagctca acaaagttct tcaaacaaca gcaacttcat
    19621 ggaaagaacg tgtgtaagaa agtcctccta gtttaggaac atgaatctaa aaaaatttaa
    19681 aaaaagttgt atgtaaaggt ttacaaaata acttacttgt gctatactta aatcacaagt
    19741 taatacaagg tgagtgttac taagtaatat taggcatgat cacaggtgaa ttagaaatca
    19801 gctgattttc tagttcattt gtggtcattt tttgtactca tataccttta agatataaaa
    19861 ggaggttgac atgtatcgaa ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa
    19921 tgataaggga gaagaggtga ttgtaattgg taaggggatt gcattcggaa agaagaaggg
    19981 ggatttgatt gctgaaaatc atgttgagaa aatctttcgg atgaagaccg aagagtccag
    20041 agaaaacttt atggctcttc tcaaagatgt tccgcttgat tttatcacag tgacctatga
    20101 aatcattgat aagctatcaa agaaatatca ttatccgatt caagagtatc tctatgtaac
    20161 cttgacagat catatttact gttcttatca agctctaact caaggaaggt acaaggatag
    20221 taatctgcca gatatttctg ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt
    20281 tgaaatttac tgtcagaagc tagcagatca ttttcctgag gacgaaatta ttcggattgc
    20341 ttatcatttc attaatgctg aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa
    20401 gaggaaagaa attctcagga atgttgaaga agttttaacg gactatgcaa ttcaacgaac
    20461 taaaaagaat aaccatttct atgatcgctt tatgatccat ttgaattatt tcttggatta
    20521 tttagacaga tctagagatg ataaccaatc acttctggat atggaagatc atattaaaca
    20581 atcctatcca aaagccttcg agattggttc caagatctat gatgtgatta cgcaacatac
    20641 gggtcttgat ttgtataaaa gtgaacgagt ttatctagtt ctacatatcc aacgtttatt
    20701 gtcataaaaa tttatttaaa actatataag gagaattcta tcatgaatag agaagaagta
    20761 acattgttag gttttgaaat cgtagcctat gctggcgatg ctcgttcaaa actattggaa
    20821 gccttgaagg ctgctgaagc tggtgatttt gaaaaagcgg acgctctggt agaggaagct
    20881 ggtagctgta ttgcagaggc tcaccacgcg caaacaagtc tattgactaa ggaagcttct
    20941 ggtgaggact tagcgtatag tgtgaccatg atgcatggtc aagatcactt gatgacaact
    21001 atcttgttaa aagacctaat gcaccattta attgaacttt acaagagagg agttaaataa
    21061 aatggataag ttaataattt ttattgagaa aggaaagcct ttctttgaga aattatcgag
    21121 aaatatatac ttaagagcga taaaagatgg ttttatttcc agtatgccag cagtattatt
    21181 ctcaagtatt tttatactaa tagctgctgt gcccaatatt tttgggttta aatggtctga
    21241 tgaacagtta gcttttattt tgaaacctta caactactca atggggattt tagctctctt
    21301 agtagctggg acaactgcaa aatcgttaac agattcagtt aatacacgta gtatggagaa
    21361 aaccaaccaa atcaactaca tgtcaacttt tttagcagct gttgttggat tgttaatact
    21421 ggcagctgat ccaattgaag gtggatttgc taatggtctt ttaggtacta gaggattact
    21481 tactgcattt ttggcagctt ttattacagt aaatatctat aaagtatgta ttaaaaataa
    21541 tgtaaccatt agacttcctg aagaggttcc accaaatatt gcacaagttt ttaaagatgt
    21601 tattccgttt gccttatctg ttctttcaat atatggattg gatttaattg ttagaaatat
    21661 ttttggtaca aatgtagcag aatctgttgg taaaatatta gcccctctat tttcagctac
    21721 tgatggttat atcggtttag ctattgtatt tggtgcttat gctttctttt ggtttgttgg
    21781 aattcatggg ccatctgttg tagaaccttt aattgtagct atcagttatg caaatataga
    21841 agctaatgtt cagcttgtgc aagctggtat gcacgcagat aaaattttaa atccagttac
    21901 tcaaactttt gttgtaacaa tgggtggtac tggtgcaaca ctagtagttc catttatgtt
    21961 tatgtggtta tgtaaatcaa aaagaaatag aattgtcgga cgtgcgtctg tagttcctac
    22021 tttctttggc gtaaatgaac caatcctatt tggtgctcca attgttttaa atcctatctt
    22081 ctttattccg tttgttactg ctcctattat caatgtttgg attatgaaat tttttgtaga
    22141 tgttctacaa atgaatagtt tcagtattat tttaccttgg acaacacctg ctccaattgg
    22201 tattgttatg ggaacggcgc tggctccatt gtcattcgtc ttggctataa ctttaatcat
    22261 tatcgacact ttaatctatt atccatttgt taaagtttat gaccatcaaa ttttagaaga
    22321 agaacggaaa ggaaactctt catctgaatt gaaagaaaaa gttgctgcaa acttcaacac
    22381 tgcaaaagcg gatgctattc ttgaaaaagc gggtgtagaa gcagcacaaa atacaatcac
    22441 taaagaaaca aatgtcctcg ttctctgtgc aggtggagga acaagtggtc tccttgcaaa
    22501 tgctttgaat aaggcagcag cagaatacaa tgtccctgtg aaagcagcag caggcggcta
    22561 tggtgctcac cgtgaaatgt taccagagtt tgatcttgtt atccttgccc ctcaagttgc
    22621 ttcaaacttt gaagatatga aagcagaaac agataagctc ggtattaaac tagcgaaaac
    22681 agaaggcgct caatacatca aattaactcg tgatggaaaa ggtgctcttg cattcgtaca
    22741 agcgcaattc gattaaggct agagactctg aaatagtctc ctatcgttac ggaaatcgct
    22801 atggcgaatt tcctattatt aattcgtcgg taaaaagata tcgtttttac ctcctcatgt
    22861 cacaattcgg tgacttggta caagaagtga gatggagaag gatggctcat tgactcctct
    22921 cctctcactt ttactttatt taaatcaaga aataggtgaa aaaaatgaca aaaacacttc
    22981 caaaagactt tatttttggt ggcgcaacag ctgcctatca agcagaaggt gctacacata
    23041 ctgatggtaa aggaccagta gcgtgggata aatatcttga agataactac tggtacactg
    23101 cagaaccagc cagtgatttt tacaatcgat atccagttga cctcaagcta gcagaagagt
    23161 atggtgtcaa tggtattcga atttctattg cttggtcacg tattttcccg actgattacg
    23221 gccaagtaaa tgctaaaggt gttgagtttt atcataattt atttgcagag tgtcacaaac
    23281 gtcatgttga gccttttgta actcttcatc actttgacac gccagaagct ctccactcaa
    23341 atggagactt cttaaaccgt gaaaatatcg aacattttgt agactacgct gccttctgtt
    23401 ttgaagaatt tccagaagta aactattgga caacctttaa tgaaattgga ccaatcggtg
    23461 atggtcaata tttggttggg aaattccctc caggtatcca gtacgacctt gccaaagtct
    23521 ttcaatcaca ccacaatatg atggtgtctc atgcacgcgc ggtaaaattg tacaaagaga
    23581 aaggctataa aggggaaatt ggtgttgttc acgccctgcc aactaaatat cctctagatc
    23641 ctgaaaatcc agcagatgtt cgtgcagctg agttggaaga tatcatccac aataaattca
    23701 tcttagacgc aacttatcta ggtcgctatt cagctgaaac catggaaggt gtcaaccata
    23761 tcttatcagt caatggtggt agcttggatc ttcgtgaaga agattttaca gcattagaag
    23821 ctgcaaaaga cttgaatgat ttcctaggaa tcaactacta tatgagtgac tggatggaag
    23881 cctttgatgg agaaactgaa attatccata atggtaaagg tgaaaaagga agctctaagt
    23941 atcaaatcaa aggtgttggt cgtcgtgtag ctcctgacta tgtaccacgc acggattggg
    24001 attggattat ctaccctcaa ggtttgtatg accaaatcat gcgtgtgaag aaagattatc
    24061 ctaactacaa gaagatttac atcactgaaa atggtctcgg ctataaagat gagttcgttg
    24121 ataacactgt ttacgatgat ggtcgtattg attacgtgaa acaacacttg gagatcttgt
    24181 ctgatgcgat tgcagatgga gctaatgtaa aaggttactt catttggtca ttaatggatg
    24241 tcttctcatg gtcaaacggt tatgagaaac gttatggtct cttctacgta gattttgaaa
    24301 ctcaagaacg ttatcctaag aaatcagctc actggtacaa gaaagtagcg gaaactcaga
    24361 ttatagacta gtagaattag tcattagata tagaatttta gtgagtcaaa aagatgttca
    24421 aagattttat ccaatctatt tatgaaaaaa agtttatatt ataaatttcg aaaaatgctc
    24481 tcaaataccg tgtttgacga gtgaagaatt gaaaagtctt ggaaaatggt atgtctcgac
    24541 tggtaaagaa tggatttgtc attcagatga tgagctggaa gaatttaaaa atctattttt
    24601 aaattttatc aatcctgaag aatgggatac tatctccttt gattcagatt ttatgccgtt
    24661 tcaacaatcg taaccaattt ctcaaaaaag ttaaatctta tatttagtac tctgtaaaac
    24721 tcttatctaa tcacgttgct tatactcaat gaaaatcaaa gagcaacttt aaactaggaa
    24781 gcgagtcgca gatttctcaa tgcatagctt tgaggaattg ggcaaaaagt ctttgatata
    24841 gaaaaaagca tagtatcagg tgttgaaaca cctgatacta tgctttttat tgtgggaaga
    24901 tttacttttt ttcttctgaa attgagttgt tacccaggct ctttcagttt attaaggctt
    24961 gatgacttta atgtgtttag atagcttaaa aaggattgaa tcacttagtt tagaatctga
    25021 aacaatagta tcaagatttg atatattata aaaagtataa aaatcaaact tattgaactt
    25081 actatgatct gcgagtaaat attttttatt agaattattt aaagcgatgc gttgagcctc
    25141 tccctcttcc tcgctaaaag tagctagagc tccgttttga ataccattac agctaacgaa
    25201 agctttagaa aattggagat tagagagatt ttgtagggtc aatgtgccaa caaaagcacc
    25261 tgtaatatcg cgataatttc cacctatcaa aatcaaatct gttaattttc gttcgcttaa
    25321 aatcagaaaa acaggtagac tgttggttac gacgcggata ttgtcaatag gcaactcacg
    25381 cgcaaaaaac tctaatgttg ttcctggtcc aatgaaaata gtttctcttt cttctactag
    25441 actgcctgca aaatgggcta tttcttgttt ttctgccgtt tggagggctt gtttttcaat
    25501 atttgatcgc tcattagtca aaagggagtt ggttcgaagt ttttcagctc caccatgcac
    25561 acgaatcagc aaatctttat cagctaattc ctgtaaatag cgccttgcag tcatatctga
    25621 aacggctatt tcgtccataa tctgtttaac tgttatggtt cctttactat ttactatctc
    25681 taaaattttg gttaattttt cttgtttgag catattatca cctcgtttcc tactactatc
    25741 ttaccataaa caaactcatc attcaaatac aaaaacaaca aaatgaaaca aaaacaaaaa
    25801 tatcgaagtt tgttttcaaa actttcgata tttttgttgg gttattattt tgttgtttct
    25861 agtttacttt ttgatggtta agagtggtgg agaattatac tcaatgaaaa tcaaagagca
    25921 aactaggaag ctagccgcag gctgtacttg agtacggcaa ggcgaagctg acgtggtttg
    25981 aatttgattt tcgaagagta ttagtccaaa ccgtagttgt agtcatcatc ttgcatggct
    26041 tcaacttcgc caagaaggta accatttccg acttgagaga agaagtcatg gttggaagtt
    26101 cctgttgaaa taccgttcat aacgattggg ttgacatctt cagctgaatc tgggaaaagt
    26161 ggatcttgtc ccatgttcat gagagcttta ttggcattgt agcgaaggaa ggttttaacc
    26221 tcttcagtcc aaccaacacc gtcataaaga ctctctgtgt agccttcttc attttcataa
    26281 agagtataga gtaggtcgta catccattct ttgagttttt cttgctcttc ttcaggtaat
    26341 tcattgaaac caagttggaa tttgtaacca atgtaggttc cgtgaacaga ctcgtcacga
    26401 ataatcaatt taatgatttc tgcaacgttg gcaagtttgt tgttaccgag atagtagagg
    26461 ggagtgaaga aaccagagta gaagaggaag gtttcgagga agacgctggc aactttcttt
    26521 tcaagtgggc tgccgtttag gtagatttcg ttgacaatct cagccttctt ttgtaggtaa
    26581 ggattggtat tggtccattc gaaaatttct tcaatctcag ccttagtatt caaggtagaa
    26641 aagattgatg agtaagattt agcgtggaca gattccataa attggatgtt attgaaaaca
    26701 gcttcctcat gtggtgtacg gatgtctgcg cgaagggctt gaaccccagt ttcagattgc
    26761 atagtgtcaa gaagggttaa accaccaaaa acttttccga ccaagtcttt ctctttgtta
    26821 gatagctttc tccagtcatc caagtcgttt gataagggaa tacgtgtatc gagccaaaat
    26881 tgctccgtca gtttttccca agttgatttg tcgatgacat cttcgatggc attccagtta
    26941 atggctttgt agtaagtttc catttaaaat ctctttctgt gtttagtatt gcgaactcac
    27001 aattatttct actttaccat aattctatag gagtatcgca caaaaagtcg gaagcccgac
    27061 ttttaaaatg ttacataaat tatgttatga catagtagat ttgattttat cagtgctgct
    27121 tagggaaaaa tagtgtttct atgctagaaa ctaaatcaca cagctttcac attggttggc
    27181 gccgacttct ccaccgtcat ctgtaaaggt acggacgtag tagatagact tgattccctt
    27241 gttaaaggca tagttacgaa ggatggacaa gtcacgtgtc gtttgtttat tttccctctt
    27301 ccattcgtaa aggccttttg gaatgtcact acgcatgaag agggtgagtg aaagtccttg
    27361 atccacgtgt tcagtcgcag cagcgtaaac atcgatgact ttacgcatat ccatatcgta
    27421 ggcagaagtg tagtaaggaa tggtttctgt agacaagcca gcagcagggt agtagatttt
    27481 accaattttc ttttcctgac gttcttcaat acgttgcgta atcgggtgga tagaagcaga
    27541 aacatcgttg atgtagctga tagaaccatt tggcgctaca gcaaggcgat tttggtggta
    27601 aagaccatcc tcttgaacct tgtcgcgaag ttcagtccaa tcagcaacac cagggataaa
    27661 aacatttttg aagagttctt taacacggtc tgatgttgga acaaattcac cagttacata
    27721 cttgtcaaag taacttccgt tagcatagtc tgatttttca aagttgtgga aggtaatacc
    27781 acgttcacgc gcaatattgt ttgactctac caaggtccag tagttcataa gcataaagta
    27841 gatgcttgta aattcaacag actcaggtga accatattca atgagttgtt gggcaaggta
    27901 gctgtgcagt cccatggcac cgagaccaaa ggtgtgggct tggctatttc catggtcaat
    27961 cgttggtaca gctacgatat gtgaactatc tgtaacgaaa gtaagggcac gaaccatagc
    28021 acggatagaa cgaccaaaat caggtgaagt catcatgtta accacgttgg ttgaacccag
    28081 gttacatgaa acatctgttc ccatttgaag gaattcttga gcatcgttga tcaagcttgg
    28141 ttcttgaact tgaagaatct cagaacacaa gttactcatg ataatctttc catcgacagg
    28201 atttgcacgg ttagccgtat ctatgttgac tacataagga tagccagact cttgttgcaa
    28261 tttagagatt tcagtttcca aatcccgcgc cttgattttt gtcttgcgaa tatttggatt
    28321 tgcgaccaat tcatcgtatt tttcagtaat gtcgatgtaa ttgaatggca caccgtattc
    28381 tttttctaca gagtaagggc tgaagaggta catttcttca tttttacgag ccaattcgta
    28441 gaatttatca ggtactacaa caccaagtga tagagtcttg acacgtactt tttcatcagc
    28501 gttttctttc ttagttgaaa ggaaagcgat gatatctggg tgaaagacgt tgaggtagac
    28561 aacaccggca ccttgacgtt gccccaattg gttggagtaa gagaagctgt cttcaaaaag
    28621 cttcataaca ggaacgacac ctgaagcagc tccttcatag cctttgatag gtgcaccagc
    28681 ttcacgaagg ttgctgaggg taattcccac accaccacca atacgtgaaa gttgaagagc
    28741 tgagttgata gaacgtccga tagagttcat atcatccgtc acttggatta ggaaacaaga
    28801 taccaactcc ccacgacgag cacgtccagc attcaagaag gaaggagtag caggttggta
    28861 gcgttggtgg atgatttcat tggcaatatc gattgcaaca gcttcattcc catcagcgaa
    28921 ataaagggcg ttgaagaaga cacggtcttc catattttca agatagtatt caccgtcatt
    28981 agtctttaag gcatattgat tgtaaaattt ataagctgcc atgaatgact tgaattggaa
    29041 gttttggtct ttgataaatt gagccaattc ttccaagaac tctggacggt atttcttgat
    29101 aaaggctgtt tcgatgtagt tgtgttcaat gaggtaattg attttgtctt tgattgaatc
    29161 aaaaaccata gtgtttggaa ctacattttc tttaaagaaa gcatccaagg cttccttatc
    29221 tttatgaagc atgatttgtc cattaacagg acggttaatt tcgttattaa gacggaagta
    29281 agtcacgtct tcaagatgtt ttaatcccat aaaatttccc ttatctaatt acaaaagaaa
    29341 ggcttctaag ttagccctaa aagcagtttc ttctggatga tgtactaaga ttatgctaat
    29401 tgtttcagtt tttctggttg gaaacctgaa aagacttcag ttggtgtttg gataacagga
    29461 gctgcgctaa aaccgagctc tttaacttga tcgacgtact caggttgctc atcaagattg
    29521 atttcacgat aagagacatt attactgtcc aagaaacgct tggtcatttt acattggaca
    29581 caattgtttt tagaataaac ggttaccatt gtgtaactcc tcttcaaaat ttaatactat
    29641 cttagtatat cagaaaataa aattttgtca atgatttaaa ctaaatatag tggtgttctt
    29701 ttgttgtttt tatatataaa cacaatatat agtgtttgta ttgtgaaata gcaatgatta
    29761 tcctataaat tgtttttgaa gaaactatat cctgtgtttt gttatctagg atagaagatt
    29821 ttcagcaagt tatctgaaag gaaattgaag gaaaatccag aaaatgcttg aaaaaaatcc
    29881 tagaagatgg tataatacta aattgtaagg gttatcacat ataactcaaa aaaagaaaga
    29941 acaaaaggag agtcaaacta tggcttctaa agatttccac gtagtggcag aaacaggtat
    30001 tcacgcacgt ccagcaacat tgttggtaca aactgctagc aaatttgctt cagatatcac
    30061 tcttgagtac aaaggtaaat cagttaacct taaatcaatt atgggtgtta tgagtcttgg
    30121 tgttggtcaa ggtgctgacg taactatctc agctgaaggt gcagatgcag atgacgctat
    30181 cgctgcaatc tcagaaacaa tggaaaaaga aggattggca taagggaaat gacagaaatg
    30241 cttaaaggaa tcgcagcatc tgacggtgtt gcagttgcaa aagcatatct actcgttcag
    30301 ccggatttgt catttgagac tattacagtc gaagatacaa acgcagaaga agctcgcctt
    30361 gatgccgctc tacaggcatc acaagacgag ctttctgtta ttcgcgagaa agcagtaggt
    30421 acgctcggtg aagaagcagc tcaagttttt gatgctcact taatggttct tgctgaccca
    30481 gaaatgatca gccaaatcaa ggaaactatc cgtgcgaaga aagtgaatgc agaagcaggt
    30541 ctgaaagaag ttacagatat gtttatcact atctttgaag gcatggaaga caacccatac
    30601 atgcaagaac gcgcagcgga tatccgcgac gtgacaaaac gtgtattggc aaaccttctt
    30661 ggtaaaaaat tgccaaaccc agcttctatc aatgaagaag tgattgtgat tgcgcatgac
    30721 ttgactcctt cagatacagc tcaattggac aaaaactttg taaaagcttt tgtaaccaac
    30781 attggtggac gtacaagcca ctcagctatc atggcacgta cacttgaaat tgctgctgta
    30841 ttaggtacaa acaacatcac tgaaatcgtt aaagacggtg acatccttgc tgttaacggg
    30901 atcactggag aagtgattat caacccgaca gatgaacaag cggcagaatt taaagcagct
    30961 ggtgaagcct atgcgaaaca aaaagctgaa tgggcacttt tgaaagatgc tcaaacagtg
    31021 actgctgacg gtaaacactt cgagttggct gccaatattg gtactccaaa agacgttgaa
    31081 ggtgttaaca acaacggtgc agaagctgtt ggactttacc gtacagagtt cttgtacatg
    31141 gattctcaag acttcccaac tgaagatgag cagtatgaag catacaaggc tgttcttgaa
    31201 ggaatgaacg gtaaacctgt tgtcgttcgt acaatggata tcggtggaga taaggaactt
    31261 ccttacttcg atatgcctca cgaaatgaac ccattccttg gattccgtgc tcttcgtatc
    31321 tctatctctg agactggaga tgctatgttc cgcacacaaa tccgtgctct tcttcgtgcg
    31381 tctgttcacg gtcaattgcg tatcatgttc ccaatggttg cgctcttgaa agaattccgt
    31441 gcagcgaaag cagtctttga tgaagaaaaa gcaaaccttc ttgctgaagg tgttgcagtt
    31501 gcggataaca tccaagttgg tatcatgatc gagattcctg cagcggctat gcttgcagac
    31561 caatttgcta aagaagttga cttcttctca attggtacaa acgacttgat ccaatataca
    31621 atggcagcag accgtatgaa cgaacaagtt tcataccttt accaaccata caacccatca
    31681 atcctacgct tgattaacaa tgtgatcaaa gcagctcacg ctgaaggtaa atgggctggt
    31741 atgtgtggtg agatggctgg tgaccaacaa gctgttccac ttcttgtcgg aatgggcttg
    31801 gatgagttct ctatgtcagc aacatctgta cttcgtacac gcagcttgat gaagaaactc
    31861 gacacagcta agatggaaga gtacgcaaac cgtgccctta cagaatgctc aacaatggaa
    31921 gaagttcttg aacttcaaaa agaatacgtt aattttgatt aatcgaaaag tccctgcaac
    31981 tcagttacag ggactttttt tgatatttta aaaagaattt tcaagaaaat ctttcttata
    32041 aaaagtccaa ccttgaaaaa gtagtggtca gaacaaaaaa tacttaaatg gttcataaaa
    32101 ttcttgacaa gttggagatt taggagtaaa ctattaacca gttaagtaat agagaggagt
    32161 ttctgcaatt tagaaatgaa ttgcaactag aaatatcaaa tagaaagaga gtttcgatga
    32221 aaattaataa gaaatacctt gttggttctg cggcagcttt gattttaagt gtttgttctt
    32281 acgagttggg actgtatcaa gctagaacgg ttaaggaaaa taatcgtgtt tcctatatag
    32341 atggaaaaca agcgacgcaa aaaacggaga atttgactcc tgatgaggtt agcaagcgtg
    32401 aaggaatcaa tgctgagcaa atcgtcatca agataacaga ccaaggctat gtcacttcac
    32461 atggcgacca ctatcattat tacaatggta aggttcctta tgatgcgatt ttcagtgaag
    32521 aattactcat gaaagatcca aactataagc taaaagatga ggatattgtt aatgaggtca
    32581 agggtggata tgttatcaag gtagatggaa aatactatgt ttaccttaag gatgctgccc
    32641 acgcggataa cgtccgtaca aaagaggaaa tcaatcgaca aaaacaagaa catagtcaac
    32701 atcgtgaagg tgggactcca agaaacgatg gtgctgttgc cttggcacgt tcgcaaggac
    32761 gctatactac agatgatggt tatatcttta atgcttctga tatcatagag gatactggtg
    32821 atgcttatat cgttcctcat ggagatcatt accattacat tcctaagaat gagttatcag
    32881 ctagcgagtt agctgctgca gaagccttcc tatctggtcg gggaaatctg tcaaattcaa
    32941 gaacctatcg ccgacaaaat agcgataaca cttcaagaac aaactggcta ccttctgtaa
    33001 gcaatccagg aactacaaat actaacacaa gcaacaacag caacactaac agtcaagcaa
    33061 gtcaaagtaa tgacattgat agtctcttga aacagctcta caaactgcct ttgagtcaac
    33121 gccatgtaga atctgatggc cttgttttcg acccagcgca aatcacaagt cgaaccgcca
    33181 gaggtgtagc tgtccctcat ggtaaccatt accactttat cccttatgaa caaatgtctg
    33241 aattggaaaa acgaattgct cgtattattc cccttcgtta tcgttcaaac cattgggtac
    33301 cagattcaag accagaacaa ccaagtccac aatcgactcc ggaacctagt ccaagtctgc
    33361 aacctgcacc aaatcctcaa ccagctccaa gcaatccaat tgatgagaaa ttggtcaaag
    33421 aagctgttcg aaaagtaggc gatggttatg tctttgagga gaatggagtt tctcgttata
    33481 tcccagccaa ggatctttca gcagaaacag cagcaggcat tgatagcaaa ctggccaagc
    33541 aggaaagttt atcgcataag ctaggagcta agaaaactga cctcccatct agtgatagag
    33601 aattttacaa taagacttat gacttactag caagaattca ccaagattta cttgataata
    33661 aaggtcgaca agttgatttt gaggctttgg ataacctgtt ggaacgactc aaggatgtct
    33721 caagtgataa agtcaagtta gtggatgata ttcttgcctt cttagctccg attcgtcatc
    33781 cagaacgttt agg
//
LOCUS       DAVLBN010000021        32369 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLBN010000021 DAVLBN010000000
VERSION     DAVLBN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32369
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.021"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..614
                     /locus_tag="VXC24_000960"
                     /pseudo
     CDS             1..614
                     /locus_tag="VXC24_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(742..1764)
                     /gene="cbpF"
                     /locus_tag="VXC24_000961"
                     /pseudo
     CDS             complement(742..1764)
                     /gene="cbpF"
                     /locus_tag="VXC24_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1783..2604)
                     /gene="cbpG"
                     /locus_tag="VXC24_000962"
     CDS             complement(1783..2604)
                     /gene="cbpG"
                     /locus_tag="VXC24_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0493095.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(2685..2924)
                     /locus_tag="VXC24_000963"
     CDS             complement(2685..2924)
                     /locus_tag="VXC24_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493096.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3074..3340)
                     /locus_tag="VXC24_000964"
                     /pseudo
     CDS             complement(3074..3340)
                     /locus_tag="VXC24_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3365..3676)
                     /locus_tag="VXC24_000965"
     CDS             complement(3365..3676)
                     /locus_tag="VXC24_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0493097.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLT
                     S"
     gene            complement(3601..3843)
                     /locus_tag="VXC24_000966"
     CDS             complement(3601..3843)
                     /locus_tag="VXC24_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0493098.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(3844..4476)
                     /locus_tag="VXC24_000967"
     CDS             complement(3844..4476)
                     /locus_tag="VXC24_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493099.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4490..5485)
                     /locus_tag="VXC24_000968"
     CDS             complement(4490..5485)
                     /locus_tag="VXC24_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0493100.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5482..6180)
                     /locus_tag="VXC24_000969"
     CDS             complement(5482..6180)
                     /locus_tag="VXC24_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0493101.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6258..7268)
                     /locus_tag="VXC24_000970"
     CDS             complement(6258..7268)
                     /locus_tag="VXC24_000970"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0493102.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(7252..8259)
                     /locus_tag="VXC24_000971"
     CDS             complement(7252..8259)
                     /locus_tag="VXC24_000971"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0493103.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8246..9199)
                     /gene="mvaD"
                     /locus_tag="VXC24_000972"
     CDS             complement(8246..9199)
                     /gene="mvaD"
                     /locus_tag="VXC24_000972"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0493104.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(9181..10059)
                     /gene="mvk"
                     /locus_tag="VXC24_000973"
     CDS             complement(9181..10059)
                     /gene="mvk"
                     /locus_tag="VXC24_000973"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0493105.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10234..10512)
                     /locus_tag="VXC24_000974"
     CDS             complement(10234..10512)
                     /locus_tag="VXC24_000974"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0493106.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            11175..11513
                     /locus_tag="VXC24_000975"
     CDS             11175..11513
                     /locus_tag="VXC24_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV0493107.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            11413..11883
                     /locus_tag="VXC24_000976"
     CDS             11413..11883
                     /locus_tag="VXC24_000976"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493108.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            12042..13274
                     /locus_tag="VXC24_000977"
     CDS             12042..13274
                     /locus_tag="VXC24_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0493109.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(13392..14390)
                     /gene="cbpJ"
                     /locus_tag="VXC24_000978"
     CDS             complement(13392..14390)
                     /gene="cbpJ"
                     /locus_tag="VXC24_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0493110.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(14409..15371)
                     /gene="cbpC"
                     /locus_tag="VXC24_000979"
     CDS             complement(14409..15371)
                     /gene="cbpC"
                     /locus_tag="VXC24_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0493111.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(15469..16158)
                     /locus_tag="VXC24_000980"
     CDS             complement(15469..16158)
                     /locus_tag="VXC24_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493112.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(16170..17594)
                     /gene="gndA"
                     /locus_tag="VXC24_000981"
     CDS             complement(16170..17594)
                     /gene="gndA"
                     /locus_tag="VXC24_000981"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0493113.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(17670..19064)
                     /gene="mapZ"
                     /locus_tag="VXC24_000982"
     CDS             complement(17670..19064)
                     /gene="mapZ"
                     /locus_tag="VXC24_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0493114.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(19077..20234)
                     /locus_tag="VXC24_000983"
     CDS             complement(19077..20234)
                     /locus_tag="VXC24_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0493115.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(20319..20699)
                     /gene="rnpB"
                     /locus_tag="VXC24_000984"
     ncRNA           complement(20319..20699)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXC24_000984"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(20720..21049)
                     /gene="gpsB"
                     /locus_tag="VXC24_000985"
     CDS             complement(20720..21049)
                     /gene="gpsB"
                     /locus_tag="VXC24_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0493116.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(21119..21646)
                     /locus_tag="VXC24_000986"
     CDS             complement(21119..21646)
                     /locus_tag="VXC24_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0493117.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            21712..22308
                     /gene="recU"
                     /locus_tag="VXC24_000987"
     CDS             21712..22308
                     /gene="recU"
                     /locus_tag="VXC24_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0493118.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            22305..24464
                     /locus_tag="VXC24_000988"
     CDS             22305..24464
                     /locus_tag="VXC24_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0493119.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(24631..29949)
                     /locus_tag="VXC24_000989"
     CDS             complement(24631..29949)
                     /locus_tag="VXC24_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0493120.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(30249..32231)
                     /locus_tag="VXC24_000990"
     CDS             complement(30249..32231)
                     /locus_tag="VXC24_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0493121.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT         9328 a         7321 c         5759 g         9961 t
ORIGIN      
        1 aaaccagata aggaccaaga gcttaaagct gaaattcaat ccatttttat cgaacacaag
       61 ggaaattata cttatcgccg ggttcattta gaactaagaa atcgtggtta tctggtaaat
      121 cataaaagag ttcaaggctt gatgaaagta ctcaatttac aagctaaaat gcgacagaaa
      181 cgaaaataaa ggagacgttg gtaagaaggc agagaatctc attcaaggcc aatttgaagg
      241 ctctaaaaca atggaaaagt gctacacaga tgtgacagaa tttgccattc cagcaagtac
      301 tcaaaagctt tacttatcac cagttttaga tggctttaac agtgaaatta tcgcctataa
      361 tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga
      421 gaagcactat ggtggagtcc ttctttggga ttctgaaatc ggaaatgttt tatggctatg
      481 agaaaacatt taaatcactt aatcaattgg aacaagctat tatagactat attgattatt
      541 acaacaacaa gagaattaag gtaaaactaa aaggacttag tcctgtgcag tacagaacta
      601 aatcctttgg ataaattatt tgtctaactt ttggggggca gtacagaaaa accttgatac
      661 tatgcgtttt ttgattgtga agacttttat ccacctatta tacaaagtta agtatccatc
      721 acagtttaca attagccttc attacttaac ccattcacca ttatagttta agtagtaacc
      781 acctactgtg gtattaacag ctaaagcacc tgaatcatag gcatagtacc agttaccatt
      841 gacttggaac cagcctgttt tcatatctcc attacttgca tttagatagt accaagtcga
      901 accttcctga taccaaccag ttgccatagc tcctgatgaa cggagatagt accacttgtt
      961 accaaggtat tgccagccag ttctcatatc accattttca gcatctagat agtaccaagt
     1021 tgagccttcc ttataccagc cagttgccat agctcctgac gaatggaggt agtaccatct
     1081 attacctaga aattgccaac cagtttgcat aatgccagtt gttggatcta gatagtacca
     1141 tggagctgct tttagcttct cttcatcata ggtaagaggg gaatccttaa cccaaccacg
     1201 tgctagctct ccaaccgcca atctgttgat gcgcgaatca aagccaccat ccttctgtaa
     1261 ataataccaa tgaccctctt cgtaaatcca accagttttt aaagtatgat aactacgctg
     1321 atcttcaaaa taatagactc atttctctgc tgggctatca tattcttccc catgatgttt
     1381 gttggtattc gtagcagttt ttgcttctaa aacttgcttg ccaacaaatt cttgtaatac
     1441 accatcttga ccaaaataaa accaatctgg tctaagagaa atctctattc ttggagaagg
     1501 accaatcgta acccccttgt gtggagcagg tatatattgc cagccgacaa ccatctctcc
     1561 ggataaagga tcaaaataat agtacttccc atctatcact ctccagtagg tttcttttag
     1621 atcccccttt ttgtagtagg ttctaccatt ttcttggaca aactgccatc cttcagaatc
     1681 atctgcaaat actgtactgg tccctagcaa accgaagaaa aatgtggcta gtgcgacttg
     1741 catcattttt ttcaaaagct tcattttata tatcctccaa cattaaatcc actcaccaga
     1801 tgaagcgaag ttataaactt taccatcgat agtttggcta cctgtaacca ttgctccatt
     1861 tgaattgaga taataccatt ttccatttac tttttgccaa tctgtaagca tcttaccgga
     1921 actgtctaaa taataccaag tatcatttat ctcctgccaa cccgtttgtt tatcatgttg
     1981 tctataatgg taccaactac catttatttt cttccatcct tcaagagagt aacctttaag
     2041 aaccgaataa ataaatggca aatttcgttc atttaattta actgcactgt taatttgatt
     2101 agctccatct cctaaagtat gcactcctac tacacggtga ctagcatcat aaactgtaga
     2161 tccactagac ccctctaaag tatcaacttg gtaatccaag aacatgccat catcacttaa
     2221 aacttgtttt ttatctgtat acatttgatg aattttaaaa ttatatgatg gatagcctgt
     2281 gatagtcaca gttattcctg tcaaattttt ttgactagta ggaagaccca aagtccctaa
     2341 ttttgcacca atgggctctt ctagaattaa taaagccaag tcatattccc ttgcatcctt
     2401 agaatttaaa tttctaaatt ccttcaaata acgaacttcc tttactttga tctttccaaa
     2461 tagttcttga cttggactaa cagccggaag aacataaata tcatccgctt ctttcccata
     2521 gtcatgtctg tagtagttgt gagccgctgt aattaacaca ttatctttaa taaaattcgc
     2581 acttcccctc ccttctacat tcattccatc ggctactcca taatacttag ataaaaccat
     2641 agctgaagtc gaatacggat actgtaaagt attatcaatt ttaatcaaat catcattacc
     2701 gataatactt ctgattgctt ttggtagtat gaaccatacg ttggtgaaat ctcagataat
     2761 gaagaatcat tagatcctgg acctttttct agtgtctcac ttacctcata ttcttcaccc
     2821 gtactagaaa taacactcaa agcagatact gtcgataact ggctagccaa taaagtactc
     2881 gcaataattg aaatacccaa ttttttataa acagttttct tcattattgt agcctcctaa
     2941 tgtaattata gcctactatt ctaaatttct taatctacta tagaatcaag aaatctacca
     3001 ccttctttaa ataccctcca ttatcacata aacaggtaaa cttttcaatt aatgactgcg
     3061 cttttcaatc acgctagagg tacttgcttg cttctttgat actaagttca gccattcttt
     3121 ccttgttttc atcaataaag catgttaccc aagttggatt cgttttggag tagtttcgca
     3181 gaatccagcc aatggcttta ttgataaaaa attctgtttg gttcaagtta tgaagtagaa
     3241 tcttttccat taattgagta ttggtcttct cttttcttaa caactggtgg tcaatagcga
     3301 cacgtctcag ccagatatta tctgataggc tccattttat actcaatgaa aatcaaagag
     3361 caaactagga agttagccgc agattgctca aaacactgtt ttgaggttgc agatagagct
     3421 gacgtggttt gaagagattt tcgaagagta ttaagattat ttcttctagt tcagggtgtt
     3481 catacaccaa actccctact actcgatcta ggatatctac cgtgtcccac caggattttg
     3541 tcacgactaa ctgctctagc ttaggcaaat cggtttcctt tagataagac tgcattgctt
     3601 tcaaatagtt agcagccaca tattggtatt ttctaggctc cttttcccag caagtgtctg
     3661 caaaatccca atcgataatc tttgtttttt tcgcttctgg aaaatatttt tatagagttt
     3721 atttctttca ggcaccgcaa tacctagaaa agaaaattga tggcgcatat aggcttccat
     3781 ggaccttgct tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaact
     3841 catctaaaac tcctcttgcc ccaccaaatg gtgctgaaag gcatagacag ccgcctgggt
     3901 acgatcgctg acttcaagtt tggcaagaat attggacacg tgggtcttga ccgtcttgag
     3961 agagataaag aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag
     4021 aacatctcgc tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc
     4081 aaccttcttg ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc
     4141 atgaagcaat tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa
     4201 gactggcatg attttttcat tgtccaaata agaggtcaca atcaaaatct tggcttcagg
     4261 ccattcttta aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc
     4321 catgacaatg acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga
     4381 cgcctcaccc acaacttcta catcgtcttg gaggtcaaag tagcttttca aacccaaacg
     4441 gaccatttca tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat
     4501 ctaacagggg aatacggata tcaactgcca gcccttgctt gggagctgtt aataactgaa
     4561 ccgtccctgc catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt
     4621 ctaagctccc taactggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat
     4681 ctgtctgata gaggtagaca tctaggcaag atgcctgggc atggcggagg gtattgctaa
     4741 tcaactcttg caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat
     4801 tctgcttgag actaacccta agatcactct tgtcctcaag ctcttttaag agaatttgaa
     4861 tcccttctat caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc
     4921 gcaaatcctt ctgggctgtt tctaaaatag ctgtgacact ctgcaactgg gtctgcatct
     4981 tttctctatc caatttcaaa gcctgctgac tgatacccga taaaatcatg tgggccgcaa
     5041 acaactcctg actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tccttctcga
     5101 tgatttcctc ttcctgagca aggctatgat tttcagcttt ttgaagagcc tctgtcaaaa
     5161 ggttaagttt acctgataag gacttgaaac tggcatccaa atcttgatct acaacctgaa
     5221 ctacttcttg ccctgccaat aaacgcttga gattagcctg catttttctt agagaaagct
     5281 cttcgatccc tcgccaaaac agggctaaga gacaggtcat ggacatgctg aaaaccaaca
     5341 ataaaaagac aaatttttct gttttttcga catcgtgcaa aaagatagac cagtcaaaat
     5401 caagtatttc cagcaagctg tgggagaaaa aaaagacaaa taggaaggag gtgagagcaa
     5461 taatgacata ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt
     5521 caagaaaatc ttgacactct tgttactctt gagatagtct tttgtttctt gatgatagtg
     5581 ttcattgcgg agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt
     5641 aacgctgaga ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt
     5701 tctgaggata atgacattgt catgattggt taagatgacc ctctccagat gaatagtgtc
     5761 cttacccatg aagcgaaaga gattgatatc atcgaattgg caagtctggt agcttgaaaa
     5821 atgatgaaga tttccaaacc aacgattttt ctccttctta accgtcacga cctcttcaaa
     5881 aaccaaattg gtctgctctt tttcctggtt catcatcggg taaagaagaa agaggctata
     5941 gataaccgca acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa
     6001 gagaatggtt gccgctacta aaagaagatt atttccctct ttaccagtgt agtagcgaat
     6061 caaaagcaaa aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa
     6121 aatcagagct cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat
     6181 aggttcatcc tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat
     6241 ggaaaaaaag gcgctggtta cgcctttttc atctgatcct ttgcttcttt taattttcca
     6301 taaagaagat agtctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata
     6361 atcaagcgta gatctgcttt ccagccttgg acaatgccaa tcacttcttc aactgtgtag
     6421 gtttcaacca attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag
     6481 cacttaatca tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct
     6541 ttccattctt gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa
     6601 tcacgctggc cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat
     6661 aggtccactg tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca
     6721 aagcccactt ccttgaggac aataggaacg ggaatttgct tgctataatc tgctagatgc
     6781 gattgccagc ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg
     6841 acatgcactt gcaatagaac aggattcatc tcttctacag tctgaagtcc taactcgaca
     6901 ggtttgtcca atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa
     6961 aaagaatcat ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata
     7021 ccacaggatt ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca
     7081 ccagtcatgg cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa
     7141 agatcgattt catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca
     7201 aagctattat aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt
     7261 gtcgtcatgt cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt
     7321 ttttaaggtt ttggttgatt ccgcatcaaa actcagggcg atgccacagt caccaccacc
     7381 agcaccacta ctcttggcaa cggcctgcaa atcttgactg gcttctttca actgtctaag
     7441 caaaggcgtg taaatatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg
     7501 ctcgataact ttttcggctt tcccctgttc caaggcttcg accaaagaaa ccaccgtttc
     7561 ttttgaggaa cttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact
     7621 cgatacagcc acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac
     7681 ttgtgaaatt gaaaagcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa
     7741 ccaagcagcc accttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat
     7801 acaggcaagg tcgcccatgg aaccattgtc tcctcgctta agcaagacag cgctagtcag
     7861 cttgaacaag agctcctgat caacagaaac atcatacaga gccagtaaag ccttgacaac
     7921 caagacaacg acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt
     7981 gccacagatt tctagagaaa aaggtcttaa attctgacca cgaacagcga ggaagtctcc
     8041 catcaaagca atcgtttctt gaatcaagct atagtcagga ttaggcctta agtccactgc
     8101 gaaatcaaac atatctgaat agatacggta gctgtcagaa aaagcaatct cagccctcat
     8161 atagatggga atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc
     8221 tgcccaatag agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt
     8281 ttgacacaat caagcgataa cgatgaccga aaatttctga taaatgctcc aagtctttct
     8341 cctgacagaa gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt
     8401 tctcacgaag ctggcgaaca aagtccatag cctcataaga ggcatccgtc agataagaaa
     8461 aggctggact agcagtcttt gtcgtagcat gcatagccag ggcatttttc tccgttaatt
     8521 ctccaatctt ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct
     8581 cagactgacg aacccagtcg tcgaaagtcg tcgaggtttc cacacaaagt ttcatcccgt
     8641 cacggctaga gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca
     8701 agtctgtctc tacagggtaa atttctccac tatccttatc ccaggctcct agtggtccat
     8761 aaaaactccg agaagaagaa cctgaggcaa atttggcttc ctgtgccaac tgacttctat
     8821 ccaatccaag cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac
     8881 ttgaggacag acccgctgcc gtaggcatat tgttttgagt atcgatacgg acaaagccct
     8941 caccagctgg acgataacgg tcaataatct tactcatctt ggcatgctcg acctcatttt
     9001 gtagctgacc attgatgtaa aattcgtcag ctgttacatt ggctggtaaa ggcgacaagg
     9061 tcgtctctgt atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct
     9121 ctttttcttt tttctttccc caatatttga taatagcaat atttgcgtag gaacgtactg
     9181 ttacaggctc tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc
     9241 ttgtgcgtgt gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct
     9301 catcttggca cccagagcac catggctaag agtcgtttca accaaaaagt ctgcctcagg
     9361 gctactgact ccaatttctt ttaaatgtaa atgcgcttga ctgaggattt gtcccagtcc
     9421 ttcagcatct ttttgtgaaa tcgcaacttc tgcttgctgg gttaattctc ccaaggcatg
     9481 caaaaacggt agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg
     9541 accataaaca cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt
     9601 aaatcctacg ttcttgataa agcgaatagg ttggtcacta agacaggtct tagcatccaa
     9661 accactagga ttcatatggg caatcatttc agctcgattg accaagattt ctagtacatc
     9721 atgaggcaga tcagcctgat agtagtcaaa tactgcacga atggccgcta tgctgatagc
     9781 cgctgacgaa cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaatgca
     9841 ggcttctgtg atattcaaat actccagtga ggcataaacc gccatggaca aggtatcctc
     9901 ctcataaagg cgccaaggac tctctgcagg aactacctta caggtcacct ccacctccaa
     9961 aagaggcagg gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat
    10021 cttactatgt gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa
    10081 aaaacgtctt atttttcata caagtattaa ttctttccta tctattttat tatattttca
    10141 caaaaaaagc gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat
    10201 tatagttgac agaatagcca tctacggtcg tattcactgc caaggcacct gagcgctata
    10261 agcgtagtac catctgccat tgacctggaa ccaacctgtc gtcatagaac gacgaaagaa
    10321 actccatacc attaagtaaa gaggaaagtc gtgagggagc atgcgccatt gacaacctgt
    10381 tttagtgacg tacaaagtct cattaacaag tactcgtttc ggccatttat aggtgcggtg
    10441 tttggagaaa tagggttcaa tcttcgccca ttcttgatcg tttaaatcag tatcatatgc
    10501 tttgcgtatc ataactctag cttaacattt ttttgtgaat acaggttcta aataatcgac
    10561 cacgaaaatt tcttaagtgg aaaacgcctt atgaagtatg ctacgggaaa cttatgcact
    10621 taatttgaca attcaagatg taaaaatata tactatagta gattgaaact agaatagtac
    10681 acctctactt ctaaaacatt tttagaaatc gatttgactg tcctgatcga tttgtcctgt
    10741 tattatttca ttttactata atatttgata agttatccta aaagtgttat tatgttgttg
    10801 tgttatagat tgattgaatc tacctaaagg atcctattca attactagaa ctatcacata
    10861 ctcaaggtca gctcacagat gagcaactat tttggttaca atgtctacta aatttaagtc
    10921 aaacaaataa tttagtcaaa attaaaaaaa tagaggaaca taaatatgat tacaaaacag
    10981 aatgtaatag tgttctacaa tttttactag ataaaactgt aaattctgaa ggaaggatca
    11041 cttcttcaac agaatttaga aatttcgtaa gtaatttatc attccaacac ggaatagctg
    11101 gactactgtt tcctctaaat aaattgtacc ccccagaact ggattctaaa atactctcta
    11161 tcatcaagaa ggcagtgaca attagaacga cacatacata tgaatatcaa tactcactgc
    11221 tatttggtga tgcaggctat ctatggttac tcctacattt attttctatc agtaaaaatc
    11281 aatactatct acaattagca aacgtcaccg ctaagaaatt aatagagaat tatgatactc
    11341 tagaggaaat agactttgca ttgggaaaat ctggtgtcct attatcatta ataaaatact
    11401 atcaatttac caatgacaat actcttaaaa ctttcatcca caatagtata tggggaaatt
    11461 tatcattatt tcctacaaag agatacagcc aaagaaagca ttttagacta tagctttgct
    11521 catggatatt gtggaattgc atatgcttta tttgcctatt ctaaagtctt agaaccttct
    11581 atgttctata atgatctcca tacattccat gctgaattaa aaaaattatt agaaaaagtt
    11641 acttctaata ctgaaaattt aggaaattta caactttctt ggtgcgaagg aatttccgga
    11701 ataatcttat atctttgtat gtacgattgt gacggaaaca aagatattat tagtaaatat
    11761 caagaatttg tttttaacca tcatctaaaa atgatgacag gatattgcca cggaataact
    11821 agcttactac aaaccactgt ctacaatcaa aacaaattac tgatgaaaaa atccaacagg
    11881 taattttagc atgttctgaa cgagatgatc acggtttact gatgtttcaa ggagatagtg
    11941 gtaaagcaga tttgtttgac ttcggaatag gaagcagggg gtatattggt gtctattaaa
    12001 taataaattc ccattcgatg tgcagacata aggagaaaag tatgaaatta ttttggacaa
    12061 acaacatata tagacagttg ctgctaaaca gctgtttttc atcattcggc gacagtattt
    12121 tctacctcgc cattatcaat tatgtggctc agtacaattt cgctccgcta gcgattttac
    12181 tgatttccat ttcagagata gttcccctac tatcgcaact ctttctcggg attctaggag
    12241 attttcaaga aaatagagtc aaacacgcac tctgtattgc caaaatcaaa atcctgctct
    12301 acgctatttt gacactattt ctcgtcttgt cgcccttttc attaatttca gtcattatga
    12361 ttgtcatcat caacctcatc tctgacacct tgagctacct gtctgcctac atgatgaacg
    12421 ccctctacat cagtgtaatt aaggacgacc tgcatgatgc catggggttc aggcagtctc
    12481 tgatgagggt tgtccgcatt gtcgccaatc tagctggcgc attccttatc aatgttatga
    12541 gtattcaaac tatttccctt atcaacactc tgacttttgt cattgccttt ttgggcctgt
    12601 atgttattcg acataccttg tatgaggttg aaaaaaggat tgaaatgtca catacagcac
    12661 tgagttttaa gaaatatttt caacatctta aacagtcgct ggctgtgctc ctgaggttaa
    12721 aagataccgt catactactg tttctgacga ccagtatgat tgccatcttg gatgtgtccc
    12781 ctcggctgat tgccctccgc ttcatccaac agacactagc acaactgagc attgggcaac
    12841 tcttcgccct gctctccatc atcatgtctt gtggagctat ccttggcaat atgaccagca
    12901 gtaatctatt taaaaatatc cgtttcacgc acctcttggt tttctgtgag atttccctat
    12961 tggctctaat aactagtatc ctttgtcaag cctatatcgt aattttcgtg accagtttca
    13021 tcagttctac gattatcggc attctcagcc ctcgcctaca agcagctgtc tttgcccata
    13081 tccccagtga caagatgggg acggtgggct ctgctctgag cacagtagac attctcgccc
    13141 cgtccctgct ctccctatta gccctatcca tagcatcggg cgtttcggtg cagttagcat
    13201 tgatattttt gtatcttatt ttgattgctc ttatcttttg tcaatggtta gtcaagttca
    13261 acactcataa ctaacgaaaa agcatgtgta gatttcacat gcttttaatc tccccaatcg
    13321 tcaggtcaag tacaacaaag tcacttcttt gattaagcga gtgttctaat ataattataa
    13381 gcgccctgtc attaccgaac ccattcgcca ttatagttga cagaatagcc atctacggtc
    13441 gtattcactg ccaaagcacc tgagctataa gcatagtacc agttgccatt gacctggaac
    13501 caacctgtct tcatgtctcc attacctgca tttaggtagt accaagttga accatcttga
    13561 taccaaccag ttgccatagc tcctgatgaa cggagatagt accatttgtt cccaaggttt
    13621 tgccaacctg ttttcatatc gccatttggg tggtctaaat aataccaagt ggtaccttcc
    13681 tgataccagc cagtggccat tgctcctgag gaacggaggt agtaccactt attacctaga
    13741 tattgccaac ctgtttgcat aataccagtt gctggatcta ggtagtacca agctgaagca
    13801 tcatttatcc aacctgcacg tctttcacca ccaatatagt tttctccatt aatttctgtt
    13861 ttagctagat aataccagtt agactgatca taaagccaac ctgtctctaa agaatgattt
    13921 tgattaaagt aatagttcgt gtaataacgc ttctcttctt tatcttctga attttcacgt
    13981 ttttccccat actttcttcc aacactgtct tgagttttaa tctctaattc tttccaacca
    14041 acaaactctt gtagcactcc atttttatca aagtagtacc actctgactt tggaaaacct
    14101 tctaatctga taccatttgg gtaaggacca attgtactac ctttagatgg aaacgggata
    14161 tattgccagc cgacaaccat ctctccagat agagaatcaa aataatagta cttaccatca
    14221 atcactcgcc agtaggtttc tttgaggtcc ccctttttgt aataggttct accgttttct
    14281 tggacaaact gccatccttc agagttatct gcaaatactg tattcgtagc tagcaaacca
    14341 aagaaaatta ctgttagtcc agcttgcata gtttttttca aaagcttcat tttatatatc
    14401 ctccaacatt aaatccactc accagatgaa gcgaagttat aaactttacc atcgatagtt
    14461 tgactacctg taaccattgc tccatttgaa ttgagataat accattttcc atttactttt
    14521 gtccaaccta ttttcatatc tccattagaa ggatctaaat agtaccaagt tgaaccatct
    14581 tgataccaac cagttgccat agctcctgag gaacggagat agtaccattt gttcccaagg
    14641 ttttgccaac ctgttttcat atcgccattt ggctggtcta aataatacca agtggtacct
    14701 tcctgatacc agccagtggc cattgctcct gaggaacgga ggtagtacca tggagcaggt
    14761 ttgcttctat caatgtcaat agtaacatga aaatcttgag tccaaccctt agcaacttca
    14821 ccaattggta gtggattgta agaatcatca ccaaaatttc ctagcttatt taaataatac
    14881 caattgccgt cttcataaat ccagcctgtc tttacagcat aattattatc aaaataataa
    14941 gttctctttt cagcagatag aggatattgt tcaccgtata cttttcctgt attttcagac
    15001 gtttttgcct ctagtacttg tttatctgtt tgttctagca aagcaccatc ttgtccaaaa
    15061 tagtaccact tctcctgaag gccaatttcg aagactggac gattatcaaa taaatcatca
    15121 cgataacctg ttccaggaat ttctaagtat tgccaaccga caaccatctc tccaatatca
    15181 ccaaaatagt aagttttacc gtctatttta tgccaataga ttgctttatg atcatctttt
    15241 acataatatt ttctattatc cttatcaaca aatcggccac ctgtggtatt cgcaaatacc
    15301 gtatttgtag ctagcaaacc aaagaaaaag actgctagta gaacttgcat catttttttc
    15361 aaaagtttca tttatatatc ctcctaaaac gattgtagca aagacacgac tgcatgtcaa
    15421 tatataaaaa ctcctcaaaa aagcagttac acaactgcaa ctgcttttct attcttgcat
    15481 ggtgtaacca acaccacgca cggttttaat gtagcttttt tgtcctttaa catcaagctt
    15541 gctccgtaga tagcggatat agacatctac gatatttgtc tcggtcgcac tttcatactt
    15601 ccaaacactt tccaacaatt gctcacgagt caatactttc ttgcttccca taagtgtcgc
    15661 caaaaggtca tactcacggc gggtcagagc aatcatctct tcaccacgat aaaccgtgtg
    15721 atgttcaaca tctatcctaa gattgcggta ggtccttgga actttcatca gactgcagtg
    15781 ttgatcaatg aagtcccgac ctcggaagat cgccgaaata cgcgctacca gattttcgat
    15841 aaagactggc ttatagatgt atgaaactgc aaaacgctga acaacttcca gctcttcttg
    15901 caagtcttcc caatgatcta aaatcatgat gactgaggca ggtttagttc gactcaattt
    15961 ttctgcaaaa tcctgagcca tcatatctcc cagattaacg ttcaataaaa tcaaatcata
    16021 gtctgtctga agagccatgg aaagggcttt ttgcccctcc tctaccagat caacccgata
    16081 ctgctctttc tggagttcca aacttaaaaa atgagctaga tttcgttctt tctcaagtaa
    16141 taaaatccgt ttccccatgg ctgacctact tatttttcgt cataccaaga gtagtggaag
    16201 gttccttctt tgtctttacg ttggtaagtg tgagcaccaa agtagtcacg ttgtgcttgg
    16261 atcaagttag ccggaaggtc agctgaacgg tagctatcaa agtaagtaat agctgctgag
    16321 aaagttggca ctggcacacc agcttgaacc gcaagagcta cgatatcacg cactgcttgt
    16381 tgatacttag cagtaacatc caagaagtac tcgtccaaaa gaaggttggc aagatctgca
    16441 tcgcggttgt aagcatctgt aatcttttgc aagaaacgag aacggatgat acagccatca
    16501 cgccagatag atgcgatatc tgcaaatggc aagttccagt tgttttcttt agaggctaca
    16561 cgcaattgag caaatccttg tgcgtatgaa atgatttttg agaagtaaag ggcttgacgg
    16621 attttttcaa tcaattcagc cttgtctcct tcaaagttga aggcagctgg ttttggaagc
    16681 accttgctag catgtacacg ttcttctttg taagttgaaa tgtagcgtgc aaacactgac
    16741 tcagtaatca gtgacaatgg tacaccaagg tcaagagatg attggctcgt ccatttacca
    16801 gttcccttgt tacctgcagc atcaaggatg tagtctacga ttggtccatc ttggtcttca
    16861 tcgtctttac ggctcaagat atcagctgtg atttcgatca agtagctatc caattcaccc
    16921 ttgttccact cagtaaagat ttcagccata tcctctgcag aaaggcctag caagtgttgc
    16981 atcaagtcat agctttctgc gatcaattgc atatcaccgt actcgatacc gttgtgaacc
    17041 attttcacat agtgaccagc tccatcagga ccgatataag tcacacatgg tttgccatct
    17101 tctggtgctt tagctgagat ttcttcaaga acatccgaaa ccaattcgta ggcctctttt
    17161 tgtccaccag gcatgataga aggaccttca agggcacctt tttcaccacc agaaactcca
    17221 gtaccgataa agttgatacc tgagtttgcc aattcttcat tacgacggat ggtatctttg
    17281 tagaaagtgt ttcctccgtc aatcaagata tcacctttgt caaggtgtgg aagaagggct
    17341 tggatagtag catctgtacc aggtccagct tgaaccatca gcatgatacg acgaggtttt
    17401 tcgattgagt ttacaaaact ttcaacgtca tagcttggta caaaattctt ttcaggatgg
    17461 caagcaatca catcttccgt tttttcttta ctacggttgt agatagcaac tgtgtaacca
    17521 cgtgattcaa tattaagggc aaggttacga cccattacgg ccatacctac gacaccaaag
    17581 ttagcttttg tcatttgaca ctcctcttgt ttcatttgtt ttattttatc atttttactt
    17641 ttgaaaagaa agaattttgt aacgactgct tagtagtcca agtcatccgc atgaccagcg
    17701 ccatttccga caaagtagcc tgtcttacag ttaagggtaa agagataggt tccatctggc
    17761 ttatagaggt tgtaataacc attgccgtta acgatattga cacgttcaag gatatattgg
    17821 tctccagtga tatagccacg tgaacgtgaa gttgctagaa tttgttccaa aacaccatcc
    17881 gcaaaatccc aggcagagtt attactatca tcaatagcag actgattata ggcaacacga
    17941 ctggcacttc tttgaacagc aacccctgca ctcgagagac ccatattgac ttcactgcga
    18001 ctacttctag tctcatttga actacttggt tttggctcac tagtcgtatt tgaacttgct
    18061 tgacttgaac ttgagctgct agtttgactt gaacttgagc tagaagtact tgtttgctgg
    18121 ctcttaccaa gactgatagc cttatctagc actttatcaa gctccgtatt tccagtttta
    18181 atatccgtaa atttagcatc cgatttggct ttggcattgg tatccaacac accatccaca
    18241 atagctggtt tttcaaattg tgcattgaca tcttgaatgg ccttgatttg cgttactaga
    18301 ctatcatatt tagatttggc aagcgtatgt tcacgactac cttccagctt atcaagtaaa
    18361 gtcttgagtt gactcagttt atcaaactgg ctatttttca aagccgtttt attgctattt
    18421 gtgtaaaagg cgtcataaag tgtattaaaa tcatccacat ccgattgatt ggctgtagtt
    18481 gattgagaag tttcaatttc cttggtcgaa cgagccactt gacgatagac ataataagca
    18541 ctgacacaaa taattactga tacaagcgcc aaaacggtca aaataaagcc ttttttactt
    18601 ttcttttctg agtcctcttg atccagacga gaaaggtttt gctcctcttc cacttcttca
    18661 gtcatttctg ttggattttc atcatctagc aatagaggat ccaagccttg ctcctcatcg
    18721 tccagaggca agggtagtaa gatgtcttca gaagatggaa cttcctccga agaagcttct
    18781 gacttctcta cagcctcacg catctcttga attaaatcat ccagactctg agtttcaacg
    18841 aactcctctt ttttgtattg acgagtcgca aacttatccg cctcaatttc atctctgtgt
    18901 tgcttaacat acttgtccaa aatggaatcc tcaggcaaga ctcctgcttc cacttcttca
    18961 tttttacgaa tagcttgacc aactgttagc tcttttgctt catcaaaatc aaattgcggt
    19021 tcttgacctt cttttttatg acgatttcgt ctttttttac tcatgagtat ccctttctat
    19081 tttacctctt gccgtttgac acgctgacca aaatattgat atagatccac tttcaaggtt
    19141 ccgttgtata acttacgctt cttatctgct tggctaccat acttgctttc aaaagcttca
    19201 tcactagtca ggataaattt gctccaagtt ttcagcggtg caaatacttg ccccatctca
    19261 gcatagagct tggtcactcc tgcatcatct gacaaacgtt caccataagg cggattggaa
    19321 atgattactc cattgatttt atcggaacgt aaatcctgca cgcgcatctg cttaaaagta
    19381 atatctcctg caacaccagc tgcctgagca ttggccttag caatttccac catgcgagca
    19441 tcaatatcac agcccatgat atccaactca agcttacgtt ctactttttt agccgcttct
    19501 gtgcgcactt cttgaatcaa gcgatcgctg atccagttcc attcatcaaa tgcaaaagag
    19561 cgacgaagac ctggcgccat ctttctagca atcataactg cctcaataca gaaagtcccc
    19621 gaaccacagg tcggatcaat caaaggcttg tctggatacc agttagaaag ttgtaaaatg
    19681 gctgctgcca tattttcctt gataggagcg ccaccttttt cggtacgata accacgttta
    19741 aagaggctag acccggtcgt atcaatcatg acagttgcca catctttgag aatagagacc
    19801 tcaatcttaa actctgggcc attctccatc agaggaaccc cttctgggcg agcatagtgt
    19861 ttctgcaatt tcttgacaac agctttctta gaaatagcct gaacactggg ctcattgtga
    19921 agtttggact taacacattt agcttttgaa atcggtaacc gagctccaag tggtaaataa
    19981 ttttcccaat ctaaagcgaa aactccctga aatagctctt caaaagtctt agctgggaac
    20041 gttcctacga taattttgat acgatctgct gcccgaagcc aaaggttggt ttcgataata
    20101 gctctcacgt ctccttgaaa acgaacacgt ccattttcaa cctgacaatc gtagcccaac
    20161 tctcgcactt cacgaccaac gacagcctca agccctgctg ccacagttgc aattaaatta
    20221 aattcttttt tcatgttaca gtcttgcaag acctttctat atgtccactt taaaaaatga
    20281 ggttgagaaa atttctcagc cccaacctat atgcaatttt ctataagcca tgttttgttc
    20341 cagaagtgac taggaccact tccttcgata atcatctgtc taccactaac agctctagct
    20401 gatagcagtc agaatactac gttcgtttcc gcatactcca tgccccgacc aaaatttggg
    20461 ttgctagctt gaggggttta ccgcgttcca ctctctctgt ttccagaaag actccgtcac
    20521 tgtggcactt tcaagcctac tctggcctat ccaaggactt agccatttca actgccgtaa
    20581 cgatttctcg tccctaggct tatggtttcg cctagcacaa acactacagg catcacagcc
    20641 tgtgctagca tggactttcc tcatgagaag caattctcct cacgcgatta tccaaaaatt
    20701 gcacatctca aataactact taaaaatctg agttatctaa aatttgttta ccaaaaactt
    20761 ctttttccaa tctattcagg cgtttcaaaa tatcaaaatt cgtcatagaa cttgtaattg
    20821 ccgcttcaag gggttctgct tgaactggtg aaggtttcgg tttacgagtt aattcttcct
    20881 tcaaatccgc aatttcctga cgaagtgact tgaccaaggc agcataggtt tcatagtcct
    20941 tgatgacatc gtctaaaaac tcgtcaactt ctactttatt atagccacgg acttcacgtc
    21001 caaactcttg ttcaaaaata tctttcgctg aaaaaataat acttgccatg tctctctcca
    21061 ttctcgcttg ctagtattat tatataaaaa aaggcaaaca aaaatcaagg tcaaagcttc
    21121 aattttcgga aaaattttca gcaagttcat ttaattgatc aaatgttaat ctctttataa
    21181 aatagtcctc ttgatttttc atcttttggt aaaaataagc tagttttgtt tcattttctt
    21241 catcataaaa aagataggaa ctagtcgtgt tttccagcaa aaactgctgg taatctctta
    21301 actgcccctt gtgttcatag cgaggataag catatttgac aaagtctacc tgcttaaagc
    21361 gactcagttt catctgatta ccttcattcc aattttcccc atgggtttca aaagcaaaaa
    21421 tggtggccaa ctggaaaccg tattcggttt tcatctcctg agcaacctct aaaacccaat
    21481 attcaaaacc caaacttcct gtaaacacaa gccaagacac cccatctgct gccatagcct
    21541 ctaaatcttt acgtatcgct tttttaatca atttaagacg aggatcctta tcagaaaata
    21601 aacccaaatc aaaagtagaa tagcctaaaa ccaaagctgt agccattttt aaccctttct
    21661 gtgcaaatta tggtataata aagtgatgtt attgtaccaa taaggagaat tatggtcaac
    21721 tatccacata aagtttcatc acaaaaaaga caaacatctc tttctcaacc caaaaatttc
    21781 gcaaatcgag gaatgtcttt tgaaaagatg atcaatgcta ccaacgacta ctatttgtct
    21841 cagggcttgg ctgttataca taagaaacca actcctattc aaatcgtaca agtggactat
    21901 ccacaacgaa gtcgtgccaa gattgttgaa gcctattttc gacaagcttc aacgacggac
    21961 tattctggcg tttataatgg atattacatc gactttgaag tcaaggaaac aaaacaaaaa
    22021 cgtgcgattc cgatgaaaaa ttttcatcca catcagattc agcatatgga acaagtcctt
    22081 gcccaacaag gaatctgctt tgtccttctt cacttttctt ctcagcaaga aacctactta
    22141 ttgccggcat tcgatttgat tcgcttctat catcaagata agggacaaaa atcaatgcca
    22201 cttgaatata ttcgagaata tggatatgaa atcaaggctg gtgccttccc tcaaattcct
    22261 tatctcaatg ttatcaaaga acatttatta ggtggtaaaa caagatgaac aaaccaacga
    22321 ttctgcgcct aatcaagtat ctgagcatta gcttcttaag cttggttatc gcagccattg
    22381 tcttaggcgg aggagttttt ttctactacg ttagcaaggc tcctagccta tccgagagta
    22441 aactagttgc aacaacttct agtaaaatct acgacaataa aaatcaactc attgctgact
    22501 tgggttctga acgccgcgtc aatgcccaag ctaatgatat tcccacagat ttggttaagg
    22561 caatcgtttc tatcgaagac catcgcttct tcgaccacag ggggattgat accatccgta
    22621 tcctgggagc tttcttgcgc aatctgcaaa gcaattccct ccaaggtgga tcaactctca
    22681 cccaacagtt gattaagttg acttactttt caacttcgac ttccgaccag actatttctc
    22741 gtaaggctca ggaagcttgg ttagcgattc agttagaaca aaaagcaacc aagcaagaaa
    22801 tcttgaccta ctatataaat aaggtctaca tgtctaatgg gaactatgga atgcagacag
    22861 cagctcaaaa ctactatggt aaagacctca ataatttaag tttacctcag ttagccttgc
    22921 tggctggaat gcctcaggca ccaaaccaat atgaccccta ttcacatcca gaagcagccc
    22981 aagaccgccg aaacttggtc ttatctgaaa tgaaaaatca aggctacatc tctgctgaac
    23041 agtatgagaa agcagtcaat acaccaatta ctgatggact acaaagtctc aaatcagcaa
    23101 gtaattaccc tgcttacatg gataattacc tcaaggaagt catcaatcaa gtggaagaag
    23161 aaacaggcta taacctgctc acaactggga tggatgtcta cacaaatgta gaccaagaag
    23221 ctcaaaaaca tctgtgggat atttacaata cagacgaata cgttgcctat ccagacgatg
    23281 aattgcaagt cgcttctacc attgttgatg tttctaacgg taaagtcatt gcccagctag
    23341 gagcacgcca tcagtcaagt aatgtttcct tcggaattaa ccaagcagta gaaacaaacc
    23401 gcgactgggg atcaactatg aaaccgatca cagactatgc tcctgccttg gagtacggtg
    23461 tctacgattc aactgctact atcgttcacg atgagcccta taactaccct gggacaaata
    23521 cccctgttta taactgggat aggggctact ttggcaacat caccttgcaa tacgccctgc
    23581 aacaatcgcg aaacgtccca gccgtggaaa ctctaaacaa ggtcggactc aaccgcgcca
    23641 agactttcct aaatggtctc ggaatcgact acccaagtat tcactactca aatgccattt
    23701 caagtaacac aaccgaatca gacaaaaaat atggagcaag tagtgaaaag atggctgctg
    23761 cttacgctgc ctttgcaaat ggtggaactt actataaacc aatgtatatc cataaagtcg
    23821 tctttagtga tgggagtgaa aaagagttct ctaatgtcgg aactcgtgcc atgaaggaaa
    23881 cgacagccta tatgatgacc gacatgatga aaacagtctt gagttatgga actggacgaa
    23941 atgcctatct tgcttggctc cctcaggctg gtaaaacagg aacctctaac tatacagacg
    24001 aggaaattga aaaccacatc aagacctctc aatttgtagc acctgatgaa ctatttgctg
    24061 gctatacgcg taaatattca atggctgtat ggacaggcta ttctaaccgt ctgacaccac
    24121 ttgtaggcaa tggccttacg gtcgctgcca aagtttaccg ctctatgatg acctacctgt
    24181 ctgaaggaag caatccagag gattggaata taccagaggg gctctacaga aatggagaat
    24241 tcgtatttaa aaatggtgct cgttctacgt ggagctcacc tgctccacaa caacccccat
    24301 caactgaaag ttcaagctca tcatcagata gttcaacttc acagtctagc tcaaccactc
    24361 caagcacaaa taatagtacg actaccaatc ctaacaataa tacgcaacaa tcaaatacaa
    24421 cccctgatca acaaaatcag aatcctcaac cagcacaacc ataacattta tcatccagat
    24481 ttttctgggt gattttttca tagcactatt gtatttatgt gcttaacaaa agcctgagaa
    24541 gatatcttct caggcttttt ctgtactata aacctcattg gaaaagatag agactgcttc
    24601 cgtaatcttg ttaagaggtt ttactaaata ctagtctttc ttcgttttta ctacaaagag
    24661 agcagatagg gctaggctaa cacttgctag gaagagggct gtgtcagatt gactctcacc
    24721 tgttgctggc aagatttgtt caggtgtttc tggtctagct atttcttgct tataatctgg
    24781 cgtcttacct tgctcggaag ctaaagatct aagtttaaac tcaggtttct ctacagttgg
    24841 agcatctggt ttcgtagcag aatcttttaa ttggttgaga taatctgcaa agtattccat
    24901 cattctttcc gtcaagagat ggttatccgt cgcatatttc atgcttgcct gaacgctagc
    24961 tacttcctct tgattgtctt tgtctgttaa tttctgagcc ttaaccaaag ctgcttcata
    25021 gcctgacaag tcaagaggtg tttctgctac ctgtggacga gtaaagataa gttccgctgc
    25081 agattggtat ttatctccac catctccgta tgtcttggta ccagtaagga caattttctt
    25141 agccttgatt gtcttaccaa agtcaatatc ttttggtttg ttgttatttg gccaatcagt
    25201 tgcagtaaag gtatgctcct tgccagactc atctgtcaca acaagtttca catctcgcaa
    25261 gttaccattt gaacctgatc cacgtggaac ataacgaagt ccagtgattt cagttggttc
    25321 tttcaagacc atggttgcag gcttgcctac atctcctccg ccccatgatg tatgccatag
    25381 actagacaca ttgccatcaa aggcatttgc aagaccttct tgagcctgag caggagctgt
    25441 aagacttgca aagtcatctg ctaccaaagc cgttttcttc tgaaccaaag cattcttcaa
    25501 agcttcaatc ttggcaatct ctgcacgcgc ttcttccaca ctgatatcat catcggcctg
    25561 actgaggtta aagaccgcct ctttcaaagc atccatagac tctttggtgt agttagtcat
    25621 ggcaaccgtt ggcaagtagt tcttcagagc attttctgtc aacatcttac ctgttagggt
    25681 aatttcttcg atttgaagat tatccatcat gaagtcgtta taaccacgga agttggcatt
    25741 tccaccagaa tcaccacgag tattacttgc atttccagtt gagtagatac ctacccaagt
    25801 atctcctgtt tctgcacctg tcacgaggaa ggttgccttc ttggctttct tggaatctgt
    25861 ccaagtattt ggcaattcat gcatttctaa gttgcttgct tgagtgccac gacgacctga
    25921 ctggaattct cccttaccga ctacaaaagc ataggtatta tctgaacctg cttcgtattc
    25981 aaaggttaca cggtaggtct taccagcttc aaagcggaag ttttgtggga tggtttggta
    26041 aaccaagtta cgacggctaa ccagtccatt ggtcttgagt gaccaatttc catcgataac
    26101 atcatcaact ttcttaccgt tccaaccacg ttgtgtatat ggatcatgct tttcagacaa
    26161 gtgagtgcgg ttgtcttcaa caccttcgac accacccact acgaatggga agataccctg
    26221 agcaacattt tcaaagtctt gtttgaaggt gcctttacct gtatcatggt tttctccgta
    26281 catgcttgaa ttgttttcaa aggtacgaat ttcatcaaag taagttgctt gatcaccagc
    26341 ttcgcgactt aaagtaagag taacatttga tacgtccgat ccagttgtaa agaaggcgta
    26401 catgttttgg aagtaacttg tattgtcaac tgtagcattg tcacgacgtg tattgtgggc
    26461 gtaggcctta acatagttga gagcgagaga cttattggta taagtagtca cttctttttc
    26521 accagtgttt acagtgatgc tcgccttggc attactacgg ttatcgacac cgacataaac
    26581 ggcatacttg gtatttggtt tcaaaccagt taatttctga gtgagactaa ctttttcttt
    26641 gtttccttga atacgaagca tatcgtttgc cccttgagac ttgacaattt ctgccttaga
    26701 agcatcgcct gaaatggtcc agtgtttcaa ggtaccgcta ttaaatcctt gatcatagat
    26761 gtgcatgcct tcactccatg acatttcagg attggtttgt ttcgaacgat agaaaacgta
    26821 tggttgattt gctagaagat ctagggtaat tttaccatct tttacagtta gttcttgctc
    26881 ttctgtctta ccttggtcag ttagcttgta aaggtaaacc ttgctctttg cccaatcact
    26941 tggaagggtc caagttgttg caccggcctg cgtattgaag tagtacatct tttccttatc
    27001 agtagaaagt ttcttaccat ttgcatccca gttccaagga gtcaagtaag ctgaaccatc
    27061 ttggatgaca cgtccgttga gcgttactgt acgtttgcga tattgtggac tattgacatc
    27121 atttgactta cgagttacaa ctactttatt attgttagca tctaccaatt ccactcgcat
    27181 ttctggagtc catttatagg tgctaccgtt atcggtcata gtcaccggtg taccattttc
    27241 ccatttactt acagtgaagt gttggaagta cttggtcatg acgtcatggg caaataagtt
    27301 agttacatag ccattgtagt cacttcttcc ttgccagcct tcaaagtctt tcatgctgta
    27361 gccacctagc agtggatagt tggctgcacc accataactt ctgtagtccc ctacccaagc
    27421 atctttttgg tggttacgga taaagcgggt gatggcactg ttgatacctt tattggtgta
    27481 gccaccgtag gtcaagtcag ctgcccagtg atggaaggta gagtcgtact caccaccatg
    27541 gccccactcg atcgcaaagc gccagccttg tttgttaatt tctttagcaa gaacgtgggt
    27601 agcccaggca ccgttatcac ctgattgacc attaccccaa acgtccacat agataaagtc
    27661 gagaccgtca ccaagttttt tcttcaaatc ttcccaacgt gccaaacgac catgagctag
    27721 gtcataggca gcatcaatgt tgataccttg atctagccag ttccaaccat agctatagct
    27781 tccatctgga ttcttacgga gaattttttc attgaaatat ttagactcag gataagtttc
    27841 tgaagcgtta acatggatac ctagatgagc tccatatttc ttagccttct caattagggt
    27901 cttgaagtct tcgacaccac cgatacgctt accaatatca gcatagttca agtgaccaga
    27961 gtcatgacct tcactaccat atcctttaag gagaacacct tgcccaagac catctgtgtg
    28021 gagattgatt ttcttgatac catccaaggt cataaggaat ggattttgtg cttgagaacc
    28081 aaagttcatc gcgatacggt aagctgtgat atccttaact ttttcccaac cttgagggtt
    28141 gttcataatg ctacgataag caatggcacc atcctgccaa tcaactttct tgtctgcatt
    28201 ggcatcttca gtgataacaa ccttagcact tggaagttcc ttcgtgtatt ctgggaaaac
    28261 aatgccctta taagcttttt cccattgcca ttcagagctg tggattccta catagttggc
    28321 atttccgact gtttctttat aagctgtcaa acgagtccag tcattcgaac caccaccata
    28381 gctgttttga gagttactcc aaacaccagc agcaagctta tctgtagaaa caaatccata
    28441 catgtaaccc ttagccaaat ccttcattgg attggttaca tcgatatgat catctccgct
    28501 gacatgtgta ttgtttgaca tggttgcccc atcaaactta gcaccagttt gatcactaga
    28561 aacagagact aaagcattgc cgaggaaact aatagaagaa agtagttttc tttcgtcatc
    28621 gatcttttga cctggagtga cttgattgtg gttgacaatc ttggtcacat caaagtgcaa
    28681 ttgattgtcc acaacttgca agcgtactgt catttccgca ttgattaagt gagcatcatc
    28741 gcgaagcttc atcaagtact ctgctgttgt ctcattgatt ttcttataag tgacttcagg
    28801 ggtgattcgg tggttattga taaagacttg gttgaactgt tgcacctgtc ctggcaaagt
    28861 atgtccattc aaggtgtatt ccttgacacg agggaaggct tggtcaatca ctgctttgag
    28921 gaccttagac tgaatcgtgt cataagtcac cttgctatca tcaacttcag gacctgtttc
    28981 tttttcagca ggggtatcct ctgtttttac cccctcttgg ttatccgttt taacgctaac
    29041 aactgttcgc tcatcgtcat aagagcccgc cttgagaaga atcttcttct catttttaag
    29101 atggtcattg accgcagctg gtagagtcac tgtgtcaaag agattgacat cgttattgct
    29161 ggcatttagc tgaccgtctg acttgagagt gatagaaaga cggtttattg atcctgtttc
    29221 aggagcagca acacggttgc ctttatacca tgtgctatta cctggagttt tgtattccca
    29281 gaaccagcca tccttgtcat aaccgacaaa aacattatta ttggtatctt taaatttcaa
    29341 gaagacacca aagcgtgatt tgcccttttc agaatcttct ttgaaggtta aatcaacagt
    29401 tgcatttcca ttggcatcaa cggtcaagcc cttcttttca aacagggctg gtttgcctgc
    29461 gttatcattt tgagcagttg aggatagttg gttgtagcgg acaccttttt cttctcggat
    29521 agtgactgtt ccctgttgtt cttttttctc taccgtttgc cattcaggag ttaccgtctt
    29581 aggggttacc gtcttagggg tttcaggttt agcagctgca ggtttatcct cttttggttt
    29641 ttcttcagcc ggtttttctt tttcaagtgc taatagttct tcttctgtct taggtccatc
    29701 tgtaacttct ggagaacctt ggtcttctcc caccttaggc gcttcaaaat cacgcccatc
    29761 attctctttt gctgttgcaa gagcagtagc taaatcagct ggtaagttcg ccgtggaacc
    29821 agactgcacg ctatctgcaa gaaccggact tgtcccaaag aatgcagctc caatcataac
    29881 agaagcaaca cctaatgaaa atttccgaat actatattta caacgttttt caaataatcc
    29941 tttattcata aacttctaaa tcctttcatt tttgagcaag cgtttacatt tcctttttaa
    30001 aaaatactcc ttcctctgaa aatgcaatgc ttaaccctga taaataaaaa taattatact
    30061 tttaatataa caaataataa ctgagaaagc aataggaaac aagtaaaatt aacaaaaatt
    30121 ttctctattc tgacaaaaag aggctccaac ttttgggggt cagtacattt agaatctttc
    30181 tttacaaatg taaaaaagga ttcagcattc aagagaaata ctaaatcctt tcttatattt
    30241 tgcaacagtt atttcacatg ttttgcgaga tcttcttgag cctttttatt agactcttct
    30301 ttttctttca tccatttttc ctgagctttt tggtattcat ctacagtgac tgccttgtct
    30361 tgaagttcca agtatttata taagattggt tcacttgtac ctttatttcc tgacaatgca
    30421 aatggtattg taaatggtac catcttagac aagattggac gccctgtacg agatgtagtt
    30481 ggaataatca aagcactatc tgtcaaccaa gcttgggctg cagcgtattt atcatagcgt
    30541 ttagcaacat ctgtagcctc atcaccagcc tcagtaacca atttttcgta gtcatataga
    30601 cctacttttt tagcagctac attatcttcc cctgagtcaa accctaaata tgttttagta
    30661 ctttctccta cagatggttt gatgatatca aggtaggttg atggatcggc aaagtctgga
    30721 ccccaaccga cattatctga taaatcccag tcttcgccag cagcattttc agcaaaatat
    30781 gtaatattgt ttacttcgtc tttttgtagt tgttggatat caataatgac attatcagct
    30841 cctaaagttg cttccaagga ttgtttcata gattggacgc gctgaacttt tgtagttgct
    30901 gtctggtcaa ctggcatatc caaatgaatt gggaaagtca caccttctgc ttgtaaggct
    30961 gatttagctt tagcaaattc agccttggct ttttctggat tgtaaagacc atcctgagaa
    31021 tctgcaagat taacatcctt ccattcatcc ccataagtaa ccaatttctc tttgaccata
    31081 tcgccaaagt ttttaccatc tgcttgaaca aatgttggtg gaacaaagat attacgtaag
    31141 attttgcttg ctccagtttg tccattcaac tgagaggcat aggctgtacg atcaaaacca
    31201 aaggcaatag cctgacggaa atccttgttt aagagagcct ttttagtcga tgccttttgt
    31261 tcgtcgctgg tcttagatgt gtatttatag gactgacggt caatatttgt accaactaaa
    31321 tacgtaatag agtcttgttg agtatagaca atattgtcct tcatactctt ctcaagctct
    31381 gcgaaacttg cacttgttgg atagagacga gctgctgtaa ggctaccatc tttaaagttt
    31441 tctgcaggtt tgctggtatc ttgaccatcc cagaatgaca atttaacttt gtcaatatgc
    31501 acattgtcct tatcccagta gttcggattt ttcgcaaatt caacagaaga tttggtcaca
    31561 atggatttca acaaataagg accgttatac aagagactat ttggatccgt agctttggca
    31621 aaatcatccc cttttgaatt caaaaactct tcattaactg gagccattac tcccattgtt
    31681 gtcttagaat tccagaagct ttctggtttg ttcaaagtgt actgaactgt ctgttcatcc
    31741 agagccttaa ttcctacttg tgagaaatct ttgatttccc cttttacata gccatccaat
    31801 cctttgattg attcttgaac aaggtaaaga gcatctgatt ttttatcagc agcatatttt
    31861 agtcctgtta caaagtcttg agctttgact gccgcgtatt cttcaccttc agaagtatac
    31921 cattttgcat ccttacggat agtataagtg taagtcaatc catccttgga tacagaccaa
    31981 tcctcagcca tagacggcac aaagttcccg tagcgatcat tttctagcaa accatcaacc
    32041 acgttactgg taatatttgc tgtcgcagcc ttagcagttg tcaaatagtt gaggttatca
    32101 gggtctgtct cataaatgta tgagaatgtc ttctcacctt tagtgcttga acctgatcca
    32161 gagcatgcag ctaaagtagt cgccgccaat aatgtcacgc ccgcaagggc aagtagtttt
    32221 gaacttttca tcattttctc ctttaaaact ttctctccat tatagactct tttcagaaag
    32281 atgtcaacag aattttcaga atttttgaaa attatttttc aaacaacatc tttgcaaaaa
    32341 atatgaatat cgtaaccgcc caataacga
//
LOCUS       DAVLBN010000022        30605 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLBN010000022 DAVLBN010000000
VERSION     DAVLBN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.022"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..308
                     /locus_tag="VXC24_000991"
                     /pseudo
     CDS             1..308
                     /locus_tag="VXC24_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828316.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            317..598
                     /locus_tag="VXC24_000992"
     CDS             317..598
                     /locus_tag="VXC24_000992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493122.1"
                     /translation="MYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTKLLCIYSEG
                     DSFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVPKLILSWSHRN"
     gene            658..1875
                     /locus_tag="VXC24_000993"
     CDS             658..1875
                     /locus_tag="VXC24_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0493123.1"
                     /translation="MDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTD
                     GNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGG
                     QDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYE
                     LYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEIS
                     KIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFD
                     FAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPS
                     YFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVA
                     DDNEGDENDDADY"
     gene            1862..3178
                     /locus_tag="VXC24_000994"
     CDS             1862..3178
                     /locus_tag="VXC24_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0493124.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            3353..4339
                     /locus_tag="VXC24_000995"
     CDS             3353..4339
                     /locus_tag="VXC24_000995"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0493125.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4403..4474
                     /locus_tag="VXC24_000996"
     tRNA            4403..4474
                     /locus_tag="VXC24_000996"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4436..4438,aa:Arg,seq:ccg)
     gene            4657..5355
                     /locus_tag="VXC24_000997"
     CDS             4657..5355
                     /locus_tag="VXC24_000997"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0493126.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5346..8885
                     /gene="smc"
                     /locus_tag="VXC24_000998"
     CDS             5346..8885
                     /gene="smc"
                     /locus_tag="VXC24_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0493127.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8882..9676
                     /locus_tag="VXC24_000999"
     CDS             8882..9676
                     /locus_tag="VXC24_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0493128.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9676..10494
                     /locus_tag="VXC24_001000"
     CDS             9676..10494
                     /locus_tag="VXC24_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0493129.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10498..11787
                     /gene="ftsY"
                     /locus_tag="VXC24_001001"
     CDS             10498..11787
                     /gene="ftsY"
                     /locus_tag="VXC24_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0493130.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11833..13320)
                     /locus_tag="VXC24_001002"
     CDS             complement(11833..13320)
                     /locus_tag="VXC24_001002"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0493131.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(13469..14209)
                     /locus_tag="VXC24_001003"
     CDS             complement(13469..14209)
                     /locus_tag="VXC24_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0493132.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14209..16374)
                     /locus_tag="VXC24_001004"
     CDS             complement(14209..16374)
                     /locus_tag="VXC24_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0493133.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16544..17497
                     /locus_tag="VXC24_001005"
     CDS             16544..17497
                     /locus_tag="VXC24_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0493134.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17574..19562
                     /gene="uvrB"
                     /locus_tag="VXC24_001006"
     CDS             17574..19562
                     /gene="uvrB"
                     /locus_tag="VXC24_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0493135.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            19572..20135
                     /locus_tag="VXC24_001007"
     CDS             19572..20135
                     /locus_tag="VXC24_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493136.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            20101..20589
                     /locus_tag="VXC24_001008"
     CDS             20101..20589
                     /locus_tag="VXC24_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493137.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            20663..21130
                     /locus_tag="VXC24_001009"
     CDS             20663..21130
                     /locus_tag="VXC24_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0493138.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(21127..21642)
                     /locus_tag="VXC24_001010"
     CDS             complement(21127..21642)
                     /locus_tag="VXC24_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0493139.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(21654..22181)
                     /locus_tag="VXC24_001011"
     CDS             complement(21654..22181)
                     /locus_tag="VXC24_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0493140.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(22463..23026)
                     /locus_tag="VXC24_001012"
     CDS             complement(22463..23026)
                     /locus_tag="VXC24_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0493141.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(23010..23561)
                     /gene="coaC"
                     /locus_tag="VXC24_001013"
     CDS             complement(23010..23561)
                     /gene="coaC"
                     /locus_tag="VXC24_001013"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0493142.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(23573..24262)
                     /gene="coaB"
                     /locus_tag="VXC24_001014"
     CDS             complement(23573..24262)
                     /gene="coaB"
                     /locus_tag="VXC24_001014"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0493143.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            24492..26162
                     /locus_tag="VXC24_001015"
     CDS             24492..26162
                     /locus_tag="VXC24_001015"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0493144.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            26490..27665
                     /gene="mutY"
                     /locus_tag="VXC24_001016"
     CDS             26490..27665
                     /gene="mutY"
                     /locus_tag="VXC24_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0493145.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            27720..28424
                     /locus_tag="VXC24_001017"
     CDS             27720..28424
                     /locus_tag="VXC24_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493146.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            28417..29766
                     /gene="vicK"
                     /locus_tag="VXC24_001018"
     CDS             28417..29766
                     /gene="vicK"
                     /locus_tag="VXC24_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0493147.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            29768..30577
                     /locus_tag="VXC24_001019"
     CDS             29768..30577
                     /locus_tag="VXC24_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0493148.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT         9376 a         5467 c         6839 g         8923 t
ORIGIN      
        1 agaagagtta ttaaataagg caactgttgg tgaaaagttt aatgataaat taaaagaaga
       61 gtttctccag gaatggcctt tggataggat tttaacaatg tcaatcgatg aatatgtaat
      121 aggaaaggga cagcaaaata agtctttatg ctacgctctt gagaagggaa aatacaaaaa
      181 tctatttctt ggaatttctg gtggctcagc ttcaaaattt ggtatttatt ggaataaaaa
      241 aacaaacaaa tataaagatc aagctaataa tgagatttca gagttggatc agcgattttc
      301 aaaattaaaa tcagatttgt atgaaattat caaagaaggt attcgtttta actttgaaaa
      361 tcctattttt gatatgaaaa gatcaacaaa tgaatttatt ggtcgttctg ctatggtgac
      421 aaaattactt tgtatctatt ctgagggaga ttctttcttt ggtgtaaata ttaatagtca
      481 gaaagaattt tggaaccact ttgtttctca gacaaatcaa ggtggacctt atctgcaaaa
      541 tcataaaata attgaactgg tgccaaaact tatcctgagt tggagccatc gaaattagga
      601 actatgcttt ttgagtattc taagcttttt atggaaaata aggaagacaa tagtacaatg
      661 gattcatcaa acaattttcg tcatcaatta actcaatctc tattaaagtc tccaaacctt
      721 atccttcgtg gtgctcctgg cacaggaaag acttatcttg ctaaagaaat tgccaaagaa
      781 ttaacggatg gcaacgaaga ccaaatcgga tttgtacaat ttcacccatc atatgattat
      841 acggattttg tagaaggttt aagaccagta tcaaatgggg atggagctat tgagtttagg
      901 ctacaggacg gtatttttaa agatttttgt cagaaagcaa aagaaaccca attgattgga
      961 ggacaagata attttgatga ggcttgggat tcttacttag aatatataaa tgttgctgaa
     1021 gaaaaagaat atataacaaa aacatcttac ttatctgtta atagtagaca aaatttgtca
     1081 gtaaattatg atagtggtgt tccaggatgg tcactaccta gcaaatatgt ttacgagttg
     1141 tataaagata aaaattataa taagcaagaa tactacaaaa gtggtggaaa aactgtccta
     1201 gaaacattga gaaagagatt tggtttgaaa gactatgttt ccccaacaga aattgatact
     1261 gataagaaat tcgtcttcat catcgatgaa atcaatcgtg gggagatttc taagattttt
     1321 ggcgaactct ttttctctat cgaccctggc tatcgtggtg aaaaaggaag tgtttctacc
     1381 caatatgcaa atctacacga aactgatgaa aagttctata tccccgaaaa tgtttacatc
     1441 atcggaacta tgaatgatat tgatcgttca gtggatacct ttgattttgc tatgcgtcgt
     1501 cgttttcgtt ttgttgaagt tactgccgag ggtcaagttg gcatgttgga taaagagctg
     1561 aatatccatg cagaagaagc aaaaattcgt ctaagaaact tgaacgctgc tatcgaaaat
     1621 gttcaggaat taaacagtca ttatcatatt ggaccaagtt attttcttaa gttgaaggat
     1681 gtagattttg actatgaatt actctggtcc gattatatta agcctctcct agaagactac
     1741 ttgcgaggtt cttatgatga ggttgaaact ttggaaactt tgaaaaaagc atttgaactg
     1801 acaaataatg agcaaaaaga tcaggcagta gctgatgaca atgaaggtga tgaaaacgat
     1861 gatgcggatt actgataatc aacacaagat tattaaagaa aaatttgttg aagaatatcc
     1921 taaactaagc aatcttcttt tagacagaac cttggaaagt ctatcccaag atgaacgtat
     1981 tttcattttt ccaaatgatt tgactcatac tcctgatttg gataaggacc aaaagatttt
     2041 tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt ggttttcttg gatatggtca
     2101 ggaaagatta acgatttcct cacgattttc tgatgagagt aatgaccatt ttttgcatta
     2161 tctcttaaac aaggttcttc atatcaatct cactagttta gatgttgctt tgtctcgtga
     2221 agagaggctt tatcaacttt tggtgtatct ctttcccaag tatctacaag ctgctattcg
     2281 aaaaggtctt tataaggaat atcatcgatt ttctcataac gacagtaatg ttaagggagt
     2341 gattgatgta agaagccatc tcaagaaaaa tcttcctttc acgggaaata ttgcctacgc
     2401 aacgagagag ttcacctatg ataatcccct catgcagttg gtccgtcaca ctattgaata
     2461 cattaagaat cagaaaagca ttggtcaagg ggtactagat aatctctcaa ctagtcgtga
     2521 aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa ctagctgatc gtgctaagat
     2581 tattcgggga aatcaatcta aacctatacg tcatgcatac tttcacgagt acagaaactt
     2641 acaagaactt tgtctgatga tcctaaacca agaaaagcac ggtttagggt atcaagatca
     2701 aaaaatctat ggtattctct ttgatgttgc ctggctttgg gaagagtatg tttacacctt
     2761 gttgccaaaa ggttttgtac atcccagaaa taaggataag acggatggaa tttcagtatt
     2821 ttctgttggg aaacgaaaag tatatccaga tttttatgac agagaacgaa agattgttct
     2881 agatgcaaaa tataaaaaac tggaattgac tgaaaaagga atcaaccgtg aggacttatt
     2941 ccagctgatt tcctattctt atattttaaa agctgagaag gctggactga tttttcctag
     3001 tatggagcag tcagtaaata gtgaaatagg aaaagtagct ggctatggag ctcaattgaa
     3061 gaagtggtct attcgaatcc ctcagaatgc ctcattctat agtacatttt gtaaaatgat
     3121 ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa gaagtgggga gaaaataatt
     3181 tcccctcttt cttttatttt taacacaagt aaaacccgaa cgatatattt taattcataa
     3241 aataatttga caaaaactgt actttggttt ataataaatt aaggaaacgt cggaaaaggc
     3301 gtagtgatgc aagagcatag gtaggtcatt acaaaagaaa cgagacatcg atatgttaaa
     3361 tgaatttcca atttttgatt acgaagatat tcaattgatt ccaaataaat gtgtcattaa
     3421 aagccgtgca gaagcggata caagtgtcac tttaggaaat cacaccttta aactacctgt
     3481 tgtgccagcg aatatgcaga cgattttgga tgaaaatgta gcagagcaac tggctaaagg
     3541 tggttacttc tacattatgc accgttttga tgaggcagga cgcattcctt ttattaaacg
     3601 aatgcacgat caagggctca ttgcttctat ctctgtcggt gttaaggatt atgagtatga
     3661 tttcgttaga cagctcaagg ctgatgctcc tgagtatatc actattgata ttgctcatgg
     3721 tcatgcggat agcgtgattt ctatgattca acacatcaag aaagaattgc cagatacctt
     3781 tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt gaattggaaa atgctggtgc
     3841 ggatgctact aaggtcggaa tcggtcctgg taaggtttgt atcaccaagg ttaagactgg
     3901 ttttggtaca ggtggttggc agttggctgc tctacgctgg tgtgccaagg ctgcgcgtaa
     3961 accgattatc gctgatggag gaattcgtac tcacggtgat attgctaagt ctatccgctt
     4021 cggtgctagc atgatcatga ttggttccct ctttgcagga cacattgaaa gtccagggaa
     4081 aacgattgaa gtcgatggtg aacagttcaa agaatattat ggttcagcct cacaatatca
     4141 aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg cttcctgcta aaggtcatct
     4201 gcaagacact ttaactgaga tggaacaaga ccttcaaagt gctatttctt atgcaggtgg
     4261 acgtcaggtt gctgacctta aacacgttga ttatgtgatc gtgaaaaact ccatctggaa
     4321 tggggatgct tcccactaag acggggtctt tgaccaaaaa acttgttatt agagcaaatt
     4381 tctgttataa taaaacaagt ttccaccctt agtgtaatgg atatcacgta agattccggt
     4441 tcttgagatg ggggttcgat tccctcaggg tggatgtaaa catcctaaaa agcctttaat
     4501 agggcttttt tctttatcct gacccaaatt tgccgctaaa actgagaatc tctgtctaaa
     4561 gaattcccaa atgctttcca gtcccgtttt agagtgactc agggggcttt ttttgatata
     4621 ataaaaagga ctattatcag ttagaaagag gttggtatga aagaattaca aactgtacta
     4681 aagaatcatt ttgcaatcga atttgcagac aaaaatttac tggaaactgc ctttactcat
     4741 acgagttatg ccaatgagca ccgcctctta aaaatttcac acaatgaacg cttggaattt
     4801 ttaggagacg ctgttctaca gttattgatt tcagaatatc tatataaaaa atatcctaaa
     4861 aagcctgaag gtgacctatc aaaactccgt gctatgattg tccgtgagga gagtttagct
     4921 ggttttgcgc gtgattgcca gtttaaccag tttatcaagt tgggtaaagg ggaagaaaaa
     4981 tcaggtggtc gcaatcgtga caccattctt ggtgatgcct ttgaagcctt tcttggtgcc
     5041 cttcttttgg ataaggatgt ggccaaggtc aaggaattta tctatcaagt catcattcct
     5101 aaggttgaag caggcgagtt tgagatgatt acagactata aaacccatct ccaagagttg
     5161 cttcaggtca atggtgatgt ggctattcgt tatcaggtga tttctgaaac agggcctgct
     5221 catgataagg tctttgatgt agaagttctt gttgaaggta agagcatcgg tcaaggccaa
     5281 ggtcgttcta agaaattagc agagcaggaa gctgccaaaa atgccgttga gaaggggctg
     5341 gattcatgta tttaaaggaa atcgaaattc aggggttcaa gtcttttgct gataagacca
     5401 aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc caatggatct ggaaagtcca
     5461 atattacaga aagtctgcgt tgggctttgg gggagtctag tgtcaagagt ctccgtgggg
     5521 gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg caaaccgctc aattatgctt
     5581 ctgtagttgt gactctggat aatcatgacg gatttatcaa ggatgcaggt caagaaatca
     5641 gggtggaacg ccatatctat cgtagtggag atagcgaata caagattgac ggcaagaaag
     5701 tccgtctgcg tgatattcat gacctcttct tggatactgg attgggacga gattccttct
     5761 ctattatttc ccaagggaag gttgaggaga tttttaattc caagcctgag gaacgacgag
     5821 ctatttttga agaagctgct ggagttttaa aatacaagac tcgcagaaaa gaaaccgaga
     5881 gtaaactgca gcaaactcag gataatctgg accgcttaga ggacattatc tacgagttgg
     5941 ataatcaaat caagcctctt gaaaagcaag ctgagaatgc ccgtaagttt ttagacttgg
     6001 aaggacaacg taaggctatt tatttagatg ttctggttgc tcaaatcaag gaaaataagg
     6061 ctgaactaga gtcgacagaa gaagagttgg ctcaggttca agaactcttg atgagttatt
     6121 accaaaagcg tgaaaaatta gaagaagaaa atcaaactct taaaaagcaa cgccaagatt
     6181 tacaggctga aatggccaaa gaccaaggca gtttgatgga tttgaccagt ctgattagtg
     6241 acttagagag aaaattagcc ctatcgaaac tggaatctga gcaagtagcc ctcaatcaac
     6301 aggaagcaca agcccgtttg gctactttgg aggataagag aagttcactc agccaagaaa
     6361 aatctgataa agaaagctct ttagccctct tggaagaaaa tctagtccaa aataatcaaa
     6421 aactcaatcg attagaggct gaattgctag ctttttcaga tgatcctgat cagatgattg
     6481 agctcttacg tgaacgcttt gtggcccttt tacaagaaga agcagatgtc tcaaaccaac
     6541 tgacccgtat tgagaatgag ttggaaaata gtcgtcagct ttctcaaaaa caagcagatc
     6601 aactagaaaa gctgaaagaa cagttggcta cagctaaaga gaaggctggt cagcaaaagg
     6661 ctgagcttga aactgccaag gagcaggttc agaaattatt ggccgactat caagtctgtg
     6721 ctaaggagca agaggagcag aaaacttcct atcaagctca acaaagtcaa ctctttgacc
     6781 gtctggatag tctcaaaaac aagcaggcta gagcgcaaag tttggaaatt atcctgagaa
     6841 atcatagtaa cttttatgca ggtgttaaga gtgttctcca agagaaagat cgtctaggtg
     6901 ggattattgg agcagttagt gagcacctga cctttgatgt gcattatcaa actgccctag
     6961 agattgcgct tggagcgagt agccaacata tcatcgtgga agatgaagag tcggcaacca
     7021 aggcgattga tttactcaaa cgaaacagat ctggtcgtgc aaccttcctt cctttgacca
     7081 ctatcaaggc tcgtacgatt tctagtcaga accaagatac tattgctgca agtccaggat
     7141 ttctgggcat ggcagatgag ctggttactt tcgatactag actggaagcc attttcaaga
     7201 atttgctagc tacaacggcc atttttgata ccgtggagca tgcgcgtgca gcagcgcgcc
     7261 aggttcgtta tcaggttcgt atggtgacat tggacggaac agagctgcgc acaggtggtt
     7321 cttatgcagg tggagctaat cgccagaata acagtatttt catcaagcca gaactggagc
     7381 aattacaaaa agaaattgct gaagaagaag caagtttgcg ttcagatgaa gtgagtttga
     7441 agaacttgca agatgagcta gctagattga cagaaagatt agaagccatc aaatctcagg
     7501 gagagcaggc tcgtattcag gagcaaggct tgtccctcgc ctatcagcag accagtcagc
     7561 aagttgaaga gctagaaact ctttggaaac tccaagaaga ggaattaaat cgtctttctg
     7621 agggagaatg gcaagcggat aaggaaaaat gccaagagcg ccttactaca atcactagtg
     7681 aaaagaataa tctggaagct gagattgaag agattaagtc taataaaaac gccatccaag
     7741 aacgttatca aaacttgcag gaagagctag ctcaagctcg tctacttaag acagaactgc
     7801 aagggcaaaa acgttatgaa gttgctgata ttgaacgctt aggtaaggaa ctagataatc
     7861 ttgatattga gcaagaagaa attcagcgcc ttcttcaaga aaaggttgac aatcttgaga
     7921 aagttgatac ggatttgctc agtcaacagg ctgatgaagc caaaactcaa aaaacaaatc
     7981 tccaacaagg tttgattcgc aagcagtttg agttggatga tattgagggt caactggatg
     8041 atattgctag tcatttggat caggctcgcc agcagaatga agagtggatt cgcaagcaaa
     8101 ctcgtgctga agccaagaaa gaaaaggtta gcgagcgctt gcgccatcta caaagtcaat
     8161 taacagacca gtaccagatc agctacacag aagctttaga aaaggcgcat gagttggaaa
     8221 atctcaatct ggcagagcaa gaagttaagg atttagagaa ggctatacgc tcactgggtc
     8281 ctgtcaattt agacgctatt gaacagtacg aagaagttca caaccgtctg gatttcctaa
     8341 atagccaacg tgatgatatt ttgtctgcga aaaacctgct ccttgagacc attacagaga
     8401 tgaatgatga ggtcaaggaa cgctttaaat caacctttga ggtcattcgt gagtccttta
     8461 aagtgacctt caagcagatg tttggtggag gtcaggctga cctcattttg actgaaggag
     8521 acttgctgac agctggggtt gaaatttctg tccaaccacc aggcaagaaa atccagtctc
     8581 ttaatctcat gagtggtggt gaaaaagccc tatcggctct tgccttgctc ttctccatta
     8641 ttcgtgtcaa gactattcca tttgttatct tggatgaggt ggaagctgcg ctggatgaag
     8701 ccaatgttaa acgttttggg gattacctca accgctttga caaggacagc cagttcatcg
     8761 tcgtaaccca ccgtaaggga accatggcag cggctgattc catctatgga gtgaccatgc
     8821 aagaatcggg tgtttcaaag attgtttcag ttaagttaaa agatttagaa agtattgaag
     8881 gatgacaatt aaactagtag caacggatat ggacggaacc ttcctagatg ggaatggacg
     8941 ctttgatatg gatcgtctca agtctctctt ggtttcctac aaggaaaaag ggatttactt
     9001 tgcggtagct tcgggtcggg gatttctgtc tctagaaaaa ttatttgctg gtgttcgtga
     9061 tgacattatt ttcatcgcgg aaaatggcag tttggtagag tatcaaggtc aggacttgta
     9121 tgaagcgact atgtctcgtg acttttatct ggcaactttt gaaaagctga aaacttcacc
     9181 ttatgtagat atcaataaac tgctcttgac gggtaagaag ggttcatatg ttctagatac
     9241 ggttgatgag acctatttga aagtgagtca gcactataat gaaaatatcc aaaaagtagc
     9301 gagtttggaa gatatcacag atgacatttt caaatttaca accaacttca cagaagaaac
     9361 gctggaagat ggggaggctt gggtaaacga aaacgttcct ggtgttaagg ccatgacaac
     9421 tggctttgaa tccattgata ttgttctgga ctatgtcgat aagggagtgg ccattgttga
     9481 attagttaaa aaacttggta tcacaatgga tcaggtcatg gcttttggag acaatcttaa
     9541 tgacttacat atgatgcagg ttgtgggaca tcctgtagct cctgaaaatg cacgacctga
     9601 aattttagaa ttagcaaaga ctgtgattgg tcaccataag gaacggtcgg ttatagctta
     9661 tatggagggc ttataatggc agatataaaa ttgattgcat tggacttgga cgggaccttg
     9721 ctgactactg ataaaaggct gacggatcgt accaaggaaa ccttgcaagc tgcgcgtgat
     9781 cgtggtatca aggtcgtatt gacaactggt cgtcccttaa aagccatgga tttctttctc
     9841 catgagttag ggactgacgg tcaggaagat gagtatacca ttacttttaa tggtggatta
     9901 gttcagaaaa atacaggaga aatccttgat aaaacagtct tttcatatga tgatgtggca
     9961 cgtttgtatg aagaaacaga gaaattatca ctgcctcttg atgccatctc agaaggaaca
    10021 gtttatcaaa tccaatcgga ccaagaaagt ctttatgcca aattcaatcc agctttgacc
    10081 tttgttccag tggactttga agacttatct agtcaaatga cctacaacaa atgcgtgact
    10141 gcctttgctc aagaaccctt ggatgcagcc attcagaaga tttctccaga attgtttgac
    10201 caatatgaaa tctttaaatc acgtgaaatg ttgctagaat ggtcaccaaa gaatgttcat
    10261 aaagcaacag gtttggcaaa actaatcagc catcttggaa tcgaccaaag tcaagtgatg
    10321 gcttgtggtg acgaggccaa tgacctctct atgattgaat gggcaggtct tggtgttgct
    10381 atgcaaaacg ctgttcctga agtaaaggca gccgcaaatg tagtgacgcc gatgaccaac
    10441 gatgaggaag ctgtcgcctg ggctatcgaa gaatatgtgc taaaggagaa ctaagatatg
    10501 ggattgtttg accgtctatt cggaaaaaaa gaagaaccta aaatcgaaga agttgtaaaa
    10561 gaagctctgg aaaatcttga tttgtctgaa gatgttgatc ctaccttcac agaagttgag
    10621 gaagtttctc aggaagaagc agaggttgaa attgttgaac aagctgtgtt ccaagaagag
    10681 gaaatccaag acacagttga agaaagtcag gattcagagc cagctgtagg ggtttctcaa
    10741 gaagaaatag aagaattacc aaactcagaa gaattaccag aggaagagaa gcttgagcac
    10801 gaaggaactg tagaagaaaa taattctgaa gtgcttgaac cagaagctcc tcaaacagaa
    10861 gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa ctcgcacagg tttcggtgcc
    10921 cgcttgaatg ccttctttgc taacttccgc tctgttgacg aagaattttt cgaggaactg
    10981 gaagaactgc tgattatgag tgatgttggt gtccaagtcg cttctaactt aacggaggaa
    11041 ctacgttacg aagccaagct tgaaaatgcc aagaaacctg atgtacttcg tcgtgtcatc
    11101 attgagaaat tggttgagct ttatgaaaag gatggtagct acgatgaaag catccacttc
    11161 caagataact tgacagttat gctctttgtt ggtgtgaatg gtgttgggaa aacaacttct
    11221 atcggaaaac tagcccaccg ctacaaacaa gctggtaaga aggtcatgct ggttgcagca
    11281 gataccttcc gtgcgggtgc agtagctcag ctagctgaat ggggccgacg agtagatgtt
    11341 ccagtagtaa ctggacctga aaaagctgat ccagccagcg tggtctttga tggtatggaa
    11401 cgtgccgtga ctgaaggtat cgatattctc atgattgata ctgctggtcg tctgcaaaat
    11461 aaggataacc ttatggctga gttggaaaag attggtcgta ttatcaaacg tgttgtgcca
    11521 gaagcaccac atgaaacctt cttggcactt gatgcatcaa caggtcaaaa tgccctagta
    11581 caggccaaag aattttcgaa aatcacacct ttaacgggaa ttgttttgac taagattgat
    11641 ggaactgctc gaggaggtgt ggttctagcc attcgtgaag aactcaatat tcctgtaaaa
    11701 ttgattggtt ttggtgaaaa aatcgatgat attggagagt ttaactcaga aaactttatg
    11761 aaaggtctct tggaaggttt aatctaatca gaagcaaaaa tcctgcaagg cataaacttg
    11821 caggaaattt ttttattcta agcgaccatc ttgacgatag gtgatatctg gttgccaagt
    11881 ccatttggca ccgaattttt caagtaggtc aaagctggct tgaggtccca tgcttccagc
    11941 tttatagtca tgaagtgggg caccattttc agcccagagc ttttcaatac ggtcaatcaa
    12001 cttccatgac gcacaaactt catcccagtg gctaaagtta gttgagttgt tatttaggac
    12061 atcataaatc aatttttcgt atggttctgg agaagcacca gttgcagtcg catctgtacg
    12121 gtaatcaagt gagttaggag ccaagttaaa ttcttctcct acttgcttcc catttaggct
    12181 aagagagaag ccttctgttg gttgaatata gatggtcaaa atatttggag caagtggttc
    12241 tccaaagata gaatccattt gtttaaagac gatgttgaca tgggttcctt tttcagtcag
    12301 tcgtttacct gtacggaaaa agaaaggaac accacggaat cgatcgctgt ctacaaagaa
    12361 ggcaccagat gtaaaggttt cagttgttga ttctggattc acatttggct cgctacgata
    12421 agagatgtat ttcatgccat caatcttacc agagcggtat tgcccacgga taaagtgttc
    12481 tttgagttct tcatcagttg gatgatagag gtttttaaag accttaatct tttcagcacg
    12541 aatctcgtct tttgtgaagc ttgctggttt gtccatggcg aggagcgaaa gaagttgtag
    12601 agtgtggttt tggaccatgt cacggagggc accggattgg tcatagtagc caccacgttc
    12661 ttctacaccc aagcgctccg caaaggtaat ttgaacattg tcgataaaat ccttgttcca
    12721 aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag atgctttgga tcatttcctt
    12781 accaagataa tggtcgatac ggaaaatttg ttcttcgtca aatgttgcta ggagttcgtc
    12841 attcaacttg cttgcagttg cgtaatctgt accaaatggt ttttcaacga tcaagcgctc
    12901 aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt ttggcaatgg ttccaaagaa
    12961 ctgaggtgcc atagacaaga agaagagctt attgtgttca gcttggtatt tttcattaag
    13021 ctcagcttgt aattgacgca aagcaatata atgttccgaa tcattgacat catggctttg
    13081 atagtagaag tggctagcaa attcttgggc ttgctcggta ctatctgcca aatcaaggat
    13141 ggactcgaca actacagatt caaaatattc cttactccaa ggtctacggg cagttccaat
    13201 aacggcaaag tgcttggaaa gattgccgga ttgatatagt ctaaaaaggg aagggtagag
    13261 cttgcgttta gccaggtctc cactcgcacc gaaaattgta acaataacct tagatgacat
    13321 ctagctacct aatttctatt tttattccta gtcttgctag gtatgaggaa acctcatttc
    13381 ataaacttaa ttctaacata attttccgaa aaatcaaaaa ttccaatacg aggtagaaaa
    13441 actgcaagga aatccttaca gtttgagttt agacgtttaa gaccttatct aagaactctt
    13501 tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg tgttccgtct tcaaggaact
    13561 cgccatctgc agtaaagata acgcggttgg caacctgacg agcaaatccc atctcatggg
    13621 ttacgataat catggtcatg ccttgctcag ccaattcctt cataacgtta agtacgtctc
    13681 caaccatctc agggtcaagg gcagaagttg gttcatcgaa gagcatgatg tctggattca
    13741 ttgctaggcc acgagcgatg gccacacgtt gtttttgacc acctgatagg ctatctggat
    13801 tggcattagc tttatctgct agtccaacct tttcaagcaa ctccattccc aattcctcag
    13861 cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa ggtgatgttg tccaatacag
    13921 acatatgagg gaagaggttg aagtgttgga ataccatgcc gatattttca cggacgtggt
    13981 caacattggt tgttttttca gttaaatcat agccgttcac agtgatgtga ccgctagtga
    14041 cttcttctaa aagattgagg ctacggagga aagttgactt accagaacct gaaggaccga
    14101 tgatacaaac aacatctcct tcatagaact tagtcgtaat tccttttagg acttcatttt
    14161 ttccatagtg cttgtgtaaa tcatttacat caatttttaa ttttaccatt aacgaatcct
    14221 cttttctaag cgtttcgcta gtctagtcaa aagtgtgata attacaagat agaagatagc
    14281 aaggattgca tacatcttga aactttggta gttacgagca atgataatct taccagtttg
    14341 gaagagttca accaaaccga tagcagatac gatagttgta tctttaagag cgataacgaa
    14401 ttggttgaca aagtttggca acatcaattt agttgcttgt ggcaagataa tcttacgcat
    14461 ggtttttcca taagagatac ccaagcttcg gctggcttcc atttggccaa ctggaacggc
    14521 ctgaatacca ccacgaacga tttcagcgat ataagcagcc gcattgagtg agagggcaat
    14581 ggttccagct acaaagtcgt taattgggct ttgttggcct gtgatagact cgatgaagtt
    14641 tggaattccc cagaagatga aggctgcaag aatcatcaat ggaataccac gaataacgtc
    14701 aacgaaaatc tcagagatga cgcgaagaga tttgtatggg ctaacgctaa acataccgaa
    14761 gataattccg atgacaatgg caatagcaaa tgagataaga gctagagcaa gagtgatacc
    14821 aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag ccccagagcg ttgtttcgtc
    14881 aacagtactt gttgaagcag ttgaagattc gctagctagg tatttgtcaa gaatcttttg
    14941 gaattcaccg tttgctttaa ggtttgcaag tccgttgttg aacatttcaa tcagttctgg
    15001 atttgctcct tttttaacgg caaaggctgt ttcaccgatt ggagttccag agattggagt
    15061 tttcaatttt tgaccttggc tgatagaata tttgagaaca ggttcatcat ccataacggc
    15121 atcaatggca ccagtgttta aactgtcata cattgaagaa ccatcagcaa aggttttgat
    15181 tttgtagccg tatttgcttt gattttctgt taggaaggtt tgagaagcag ttccgttttt
    15241 aacaccgact gtctttcctt ttagatcttc ataagaagca atattgcttg attctttgac
    15301 accaagaatg gtattagcag tgtagtatga ttctgagaag tcaaaagttg ccttacgagc
    15361 atctgtgaca gacataccag cgatgatacc atcggcttga ccagcttgga cagcactgat
    15421 agcagcatca aaaccagggt tggtgatttc aatttcaaaa ccttggtctt tagcgattgc
    15481 cttaatcaat tccatatcaa taccagtgta ttggttgctt gaattttgga aaacaaaagg
    15541 tgcaaaagaa gaatcgctgg caatgatata tttagcctta acaggaatag cttttaatcc
    15601 tgcgagagta gttgtagttg gcactgctga agatgatgaa gcagtccatt tcttgataat
    15661 tttatcaaga ctaccatctt ttttcatttc agacaaggct tggttaaatt cagtaaccag
    15721 gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa cttcctacag cttcaccatc
    15781 catttcaata tggaggtctt gaccttggtt aatggcatat tcgataacag gtttgtcatc
    15841 catcatggca tcgatggcac cagcactcaa gctgttgttc attaaatcac cagtgtcaaa
    15901 tgttttaata gtaaagccgt atttatcttt gattgtttca aggaaacgtt gagcggcagt
    15961 tccgttttta acaccaacgg ttttgccagt taattggtcg tacttgctaa ttttgtgtga
    16021 ctttgtagta gcaatgacaa cttttgtatc atagtaagta tcagacatgg tgaagacttt
    16081 ttcacgttct ttagtctttg tcatccctgc catgatagcg tcggcttgcc cagcttgaac
    16141 cgcattgact gctgcgtcaa atccaggata ggacatctga atgttccagc ctttaatctc
    16201 agcgactttg ttaataatgt caacatcaat tcctttataa gtttgatctg aatctttaaa
    16261 ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc gtttctgctt tggcaatacc
    16321 taatgagaaa attgggaata aaattagcaa aaatgctaga aattttttct tcatttttag
    16381 tctccttttc cgaatattct ctcattatat cagaaaaagt aaaaaaaggc aaatttttat
    16441 atttttcgtg tcagaaaata taacatcgat tttttccttt ccttgaattg ctattaaaaa
    16501 gtgctataat aatagtatat atagaagaaa agaggacggg gatatgaaga acaaaagaat
    16561 atttaaagac ttccaagctt caaaaatgag tttaaacatt tacacaagcc ccttgttagc
    16621 ctttgttttt gtcttcatag gagagtttgt ggcttttact ttgtatggta ttggcttgtt
    16681 agctctcatc ggacttgcta gaaattttgg agaggctggt caaaatcttg caagctactt
    16741 gcagaccttg catcagagct tgacggataa aacaagtgac tttcgtttaa ttttaggatt
    16801 actggccttt ggttttattc ttaacactgt gttcagatgg acaagaaaag ttgagaaaag
    16861 acctattcga accttgggat tttatagaga gaatttcctc agcaatcttc tgaaaggatt
    16921 tagtctaggc ctggcacttt ttcttctgac cttgttaggt ttagtggtct taggtcaata
    16981 tcgtttggaa tccattcact tgaatcctta ttctcttgcc tttgtcgtct ttactatccc
    17041 attttggatt ttacagggga cagcagaaga agtggtggcc cgtgcttggc tacttcctca
    17101 attggcctca agaaccaatc taaaactagc tattcttata tctagcctgt tctttaccct
    17161 gcttcatatg ggcaattctg gtctcacccc tctatctcta gtaaatctct ttttattcgg
    17221 agttgccatg gctctttacc ttctcaaaac tgatacagtt tggggtgttg caggtattca
    17281 tggtgcttgg aattttgctc agggtaatct ctttgggatt ttagttagtg gtcaaccgtc
    17341 aggaacgtct ctgatgacct ttttaccaca aggcaatcaa gattggctat caggtggttc
    17401 ttttggcata gaaggttcca ttatgacaag tctggtatta ctactgctga ttgtctatct
    17461 tgctaataaa ttaaagaaag aaaatgaaag gatgtgactt cggtccgtcc ttttcttcgt
    17521 gaaaatacta taagtatgct aaaataggaa tagcacatgg agagaggatt cttatgatca
    17581 atcacattac agataatcaa tttaaactag tatcaaaata tcaaccatca ggagatcaac
    17641 cccaagctat cgagcagttg gtggataaca ttgagggggg agaaaaagct cagattctga
    17701 tgggggcgac tggaacaggg aagacctata ctatgagtca ggtcatttct aaagtcaata
    17761 aaccaactct ggttattgcc cacaataaaa ctctggctgg tcagctctat ggggagttta
    17821 aggaattttt ccctgaaaat gcagttgagt atttcgtatc ctactatgat tattaccagc
    17881 cagaggccta tgtcccttct agcgatacct atattgagaa ggatagttct gtcaatgacg
    17941 agattgacaa gcttcgccac tcagctacct cagccctttt ggagcgtaat gatgttattg
    18001 tcgtggcctc agtctcttgt atctatggtt tgggttcgcc caaggaatac gctgatagtg
    18061 tcgttagtct ccgtcctggt ctagagattt ctcgtgataa actcttgaat gacttggtcg
    18121 atattcagtt tgaacgtaat gatattgatt tccaacgcgg aagatttcgc gttcgtgggg
    18181 atgtggtaga gattttccca gcttcccgag atgaacatgc ctttcgagta gaattttttg
    18241 gagacgaaat tgaccgtatt cgtgaagttg aggctctgac aggtcaggtg ttgggagaag
    18301 tggatcattt agcgattttc ccagcgacac actttgtgac caatgacgac cacatggaag
    18361 ttgccattgc aaagattcag gccgagttgg aagaacaatt agctgtcttt gaaaaggaag
    18421 gtaaactgct tgaagcccag cgtttgaaac agcggacaga gtatgatatc gaaatgttgc
    18481 gtgagatggg ctataccaat ggggttgaaa attattctcg ccacatggat ggacggagcg
    18541 aaggagagcc tccttatacg cttctcgact tcttcccaga tgatttcttg attatgattg
    18601 acgagagtca tatgaccata gggcaaatca agggcatgta caatggagac cgttcgcgta
    18661 aagaaatgct ggttaattat ggtttccgtt tgccgtctgc tttggacaat cgtcctctcc
    18721 gtcgggagga gtttgagagt cacgttcatc agattgttta cgtttcagcg acacctggtg
    18781 actatgaaaa tgaacagacc gagacagtga ttgagcaaat cattcgtcca acgggactct
    18841 tggatccaga ggtggaagtc cgtccgacta tgggacagat tgatgacctc ttgggtgaaa
    18901 tcaatgcccg cgttgaaaaa aatgagcgta cctttatcac aactttgacc aagaaaatgg
    18961 cagaggattt gaccgactac ttcaaggaaa tgggtatcaa ggtcaagtac atgcactcgg
    19021 atatcaagac cttggaacgg acggagatta tccgtgacct gcgcttgggt gtctttgatg
    19081 tcttggtcgg aattaacctg ctccgtgaag gaattgacgt tcctgaagtg agcctcgtag
    19141 ctattctcga tgctgacaag gaaggtttcc ttcgcaacga acgtggactc atccagacta
    19201 ttggacgtgc tgctcgtaac agtgaaggcc atgtcatcat gtatgcagac acggttaccc
    19261 agtctatgca acgtgctatc gatgaaactg cccgccgtcg gaaaattcag atggcctata
    19321 atgaagagca tggtatcgta ccacagacaa tcaagaaaga aatccgtgac ctgattgccg
    19381 tgaccaaggc agttgctaag gaagaggaca aggaagtcga catcaatagc ctcaacaaac
    19441 aagagcgcaa agaactcgtc aagaaactag aaaaacaaat gcaagaagcc gtcgaagtgc
    19501 ttgactttga actggcggct cagatccgtg atatgatgtt ggaagtcaag gccttggatt
    19561 aggggaatag tatgatttat ttaagaaagt taaagagaga agatttgatg tctttatggg
    19621 aaatggctta ttcacaactt aatccagttt ggaaacagta tgatgctccc tattatgatg
    19681 attatcagta tttttcaaat tttaaagaat tcgaactaca aaaatcagaa tccattttaa
    19741 gcaactcaaa tcgccttggt atttttgttg atgataaact agttgggact gtttcgcgtt
    19801 attgggtatg taaacaaaca agatggatgg aattgggaat tggtatttat gataaaaaat
    19861 tctggaacac tggtattggg aaagttgcta tgttgcagtg gatagatagg acgtttcagg
    19921 attacttgga gttggagcat ctgggtttga caacttggtc agggaatatt ggtatgatga
    19981 aacttgctga aaaattaaga atgaaaaaag aagctcatat tccaaaagtt cgttattatc
    20041 aaggtaaata ttttgatagt attaaatatg gtattttgag agaagactgg gagaaaataa
    20101 atgacggtta ttatcaaatc aatggaaact cctaaagaga tagaaggtaa atcccttgtt
    20161 cactggcaaa cgtggagaga gtcttatgat gaccttttgc ctgcggaatt tcaggataca
    20221 atgacattag aaagatgtcg attctttagt caaaagtatc cagaaaatac attgattgcg
    20281 atggatggcg tgaaggtggt tggttttatc agttatggca attttcgtga tgagactatt
    20341 caagctggtg aaattattgc tttatatgtt ttaaaagact attatggaaa aggtatcgca
    20401 caaaagttaa tgaaagcagc tttgactgct cttaatcatt tttctgaaat tttcttatgg
    20461 gtattgaaag ataacaagcg cgccattgct ttctatcaaa aaatgggttt tacttttgat
    20521 ggacaagaaa aaatacttga acttggaaag cctataaagg aaaaacgaat ggtgttctat
    20581 tctaaataat tttaaaaaag taaaagataa tatctctggt agtaagtctg aaaatttaat
    20641 aaattagaaa gcgagtaaat ttatgtcccg ttcccaatta acaattttaa caaatatctg
    20701 tctgattgaa gacctcgaaa ctcagcgcgt ggtgatgcag tatcgcgccc ctgaaaacaa
    20761 tcgctggtct ggttatgcct ttcctggagg tcatgtagaa aatgatgagg cttttgcgga
    20821 gtctgtcatt cgtgaaatct acgaagaaac agggttgact atccaaaatc ctcaacttgt
    20881 cggcattaaa aattggccac tagatacagg tgggcgctat attgtcattt gttataaggc
    20941 gactgagttc tctggtaccc ttcaatcttc agaagaggga gaagtttctt gggtgcaaaa
    21001 agaccagatt ccaaacttaa atctggccta tgatatgcta ccattgatgg aaatgatgga
    21061 agctcccgac aagtcagagt ttttctatcc tcgccgtaca gaagacgatt gggaaaagaa
    21121 aatcttctag tcttttacta aataacctag ctgatccaag gcctcctcga tatagtggag
    21181 gtcttgttgt gtttcggctt cgactaggtg gtaatggatg ccatctgtca attcagatag
    21241 aggtctaaag tcagaatgct cgacttgttc tagaaaatgt tgcacatctc tgcgacaaga
    21301 cagtttaagc aaggtttcaa tttctccata aacgggatgg tcaatcaagg tattctggac
    21361 atgcccacca ttatcgacaa tagcaaggag ttcctgaccg atttcttcaa cttcatgttt
    21421 cactttgaaa agtttgtgaa cataaggatt ggtatcaatt tgcttataga tgtagccacg
    21481 attggtggat aggataggag cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac
    21541 ctgacgtgtg acatgaaaat gttccgccaa actttggcca ttaagggctt taggagcttc
    21601 tttcaagagt tggagcaggg cttgtttgcg atcttttgtc atagcttttc cttttaacgg
    21661 cgttttcgaa gcactttata gacagctagt gctaatgtat agtctaccat actatggata
    21721 attgtgccaa atccaactag tacaaataga acatagaaca tattttctac attggtaccc
    21781 gaagttgcgt aaaaaaggac acaggctaat acttcagcaa gggcatgaac aacagccaaa
    21841 acaaaattga aaacccagga agattttggt ttatctaggg tatcggggaa tttttgtagg
    21901 taaagagctc ctaaagcacc aaaagatata tgggaaaaag cccgaaaaac gataaccatg
    21961 ggatagccag ccatcaaaaa tccaaaacta gaggctagga tgacaaaaac tgccatcaag
    22021 ggcgacaaga acatggctat aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt
    22081 ggaatgacaa tcttgaaagg cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg
    22141 gctgtcattg tcataaattg tgtctttttc cgtgtattca caagaatctc ctttttaact
    22201 gcatatacac tagtatggta caataaacca gacaataaag caagaattta cttgggttta
    22261 tagatcattt tttagttaaa agttatagta gattgaaact agaatagtcc acctctactt
    22321 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgtcctgt tcttatttcg
    22381 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
    22441 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
    22501 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
    22561 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
    22621 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
    22681 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
    22741 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
    22801 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
    22861 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
    22921 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
    22981 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgat agtttccttt
    23041 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
    23101 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
    23161 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
    23221 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
    23281 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
    23341 agttcgatat gattgacctg atcaggatag ggttctttca tgacatccaa gtggacagga
    23401 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
    23461 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
    23521 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
    23581 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
    23641 gaagctgatt tttctcaaca aatatagctc ggtgctgacc tgctgaaatt tgagtcaggt
    23701 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
    23761 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
    23821 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
    23881 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
    23941 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
    24001 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
    24061 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
    24121 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
    24181 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
    24241 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
    24301 aaagtgataa atttttggta aaaacgaaga tttactatag tttcaaacta taaagccata
    24361 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
    24421 agttttaaga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
    24481 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
    24541 ttgatgttgt agagaaactt ggtatttctt acgacgattt ggagttgtac ggaaagtaca
    24601 aggctaaact cagctttgat aaaattcggg cagttgagag caatccagtc ggtaaattga
    24661 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
    24721 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
    24781 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
    24841 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
    24901 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
    24961 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
    25021 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggatggt tttgatatta
    25081 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
    25141 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
    25201 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
    25261 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
    25321 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
    25381 ctgaagctgg ttttggtgcg gaccttggtg ctgagaaatt ccttgatatc aagacaccaa
    25441 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
    25501 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
    25561 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
    25621 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
    25681 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
    25741 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
    25801 tgtacgataa tgacctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
    25861 gtggtagcaa agtgaacttt gagaagaaat ctcaaacaca aattgctcaa atcgttcaaa
    25921 acggttggga caaattgcca atctgtatgg ctaaaactca atacagtttc tcagacaatc
    25981 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
    26041 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
    26101 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtacta ggcttgttct
    26161 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
    26221 gactgcaagc agttcatcaa taagatttat actcttcgaa aatctcttca aactacgtca
    26281 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
    26341 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    26401 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
    26461 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
    26521 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
    26581 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
    26641 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga ttcctggact
    26701 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
    26761 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
    26821 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
    26881 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
    26941 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
    27001 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatccg gatcgtccgg
    27061 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
    27121 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
    27181 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
    27241 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
    27301 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
    27361 tctttcatca ggttgcggaa gaaagtgtga actttggccc cagtccagaa gagagtttcc
    27421 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
    27481 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
    27541 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
    27601 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
    27661 actagctatt gtgtcttctg actatttttt ggtataatag tagagaaaaa ggtgaacata
    27721 tgaaaaaaat actaattgta gatgatgaga aaccaatctc ggatattatc aagtttaata
    27781 tgaccaagga aggttatgaa gttgtaactg cttttaatgg tcgtgaagcg ctagagcaat
    27841 ttgaagcaga gcaaccagat attattattc tggatttgat gcttccagaa attgatggtt
    27901 tagaagttgc taagaccatt cgtaagacaa gcagtgtgcc cattcttatg ctttcagcca
    27961 aagatagtga atttgataag gttatcggtt tggaacttgg ggcagatgac tatgtaacga
    28021 aacccttctc caatcgtgag ttgcaggcgc gtgttaaagc tcttctgcgt cgttctcaac
    28081 ctatgccagt agatggtcag gaagcagata gtaaacctca acctatccaa attggggatt
    28141 tagaaattgt tccagacgcc tacgtggcta aaaaatatgg cgaagaacta gacttaaccc
    28201 atcgtgaatt tgagcttttg tatcatttag catcgcatac aggtcaagtc atcacgcgcg
    28261 aacacttgct tgagactgtc tggggttatg actattttgg tgatgtccgc acagttgatg
    28321 tgactgtacg acgtctgcgt gagaagattg aagatacgcc cagccgacca gagtatatct
    28381 tgacgcgccg tggtgtaggg tattacatga gaaataatgc ttgatttact gaaacaaacc
    28441 atttttacca gagattttat ctttatcctg attttgttag gtttcatcct tgttgtgacc
    28501 ctcttattac tggaaaatag acgtgataat attcagttga agcaaatcaa tcaaaaggtt
    28561 aaagatttga ttgcaggaga ttattccaag gttcttgata tgcaaggtgg gtctgaaatc
    28621 accaatatta ccaataattt gaatgacttg tcggaggtta ttcgtctcac tcaggaaaat
    28681 ctagaacaag agagtaagag gctaaatagt attctgtttt atatgacaga tggggttctt
    28741 gcgactaacc gtcggggtca gattatcatg attaacgata cagccaagaa gcaactgggg
    28801 ttggttaagg aagatgttct gaatagaagc attttggaat tgctcaagat agaagaaaac
    28861 tatgaattgc gtgatttgat tacccaaagt ccagaattgt tgctagattc ccaagatatc
    28921 aatggcgaat atttgaacct tcgagttcgc tttgccttga tacgtcgaga gtctggcttt
    28981 atttcaggtt tggtggctgt tttgcatgat acgacggagc aggagaagga agaacgcgaa
    29041 cgaagactct ttgtttccaa tgttagccat gagttacgga ctcctctgac tagcgtaaaa
    29101 tcctatcttg aagccttgga tgagggggct ttgtgtgaaa ctgtagcacc agactttatc
    29161 aaggtttctc ttgatgagac caaccgtatg atgcgcatgg tgacggatct cctccatctt
    29221 tcacgtattg ataatgctac cagtcaccta gatgtggaac tgattaactt cactgctttt
    29281 attaccttta tcctcaatcg ttttgacaag atgaaaggac aggaaaagga gaaaaaatat
    29341 gagctggtga gagattatcc catcaattct atctggatgg aaattgatac agataagatg
    29401 acgcaggttg tcgacaatat tttaaataat gctattaagt attcgccaga tgggggtaaa
    29461 atcactgtca gaatgaagac aactgaagac cagatgattt tatccatttc tgaccacggt
    29521 ttggggattc ctaagcagga tttaccacgt atctttgacc gtttctatcg tgtggatcgt
    29581 gctagaagtc gtgcacaagg tggtacaggt ctaggactgt ctatcgctaa agaaattatc
    29641 aaacaacata agggctttat ttgggccaag agtgaatacg gcaagggttc aacctttacc
    29701 attgtactcc cttatgataa ggatgcagtg aaagaagaag tatgggagga tgaagtagaa
    29761 gactagaatg agtgaaatag gctttaaata cagtatttta gcgtcgggtt ccagtggaaa
    29821 ttctttttat ctggaaacct caaaaaagaa gcttttagta gatgcaggct tgtctggcaa
    29881 gaaaattacc agtctgctag ctgaaattaa ccgtaagcca gaagacctgg atgccatctt
    29941 gattacccat gagcattcag atcatatcca tggagtaggc gttttggctc gcaagtatgg
    30001 tatggatctt tatgccaatg aaaagacctg gcaagctatg gaaaatagta aatatcttgg
    30061 caaggtggat tcttcgcaaa agcatatttt tgaaatgggt aaaaccaaaa cctttggaga
    30121 tatcgacatc gagagttttg gtgtaagcca tgatgcagtc gcaccgcagt tctatcgctt
    30181 tatgaaggat gataagagtt ttgtcctctt gacagataca ggttatgtca gtgaccgtat
    30241 ggcgggcatt gtcgaaaatg cggatggtta tcttatcgag gccaaccatg atgtagagat
    30301 tttgcgatca ggttcttacg cttggcgact caaacaacga atcctatctg accttggtca
    30361 cctttctaac gaggacggtg ctgaagctat gattcggacg ctaggaaatc gtactaagaa
    30421 gatttacctt gggcatttat ctaaggaaaa caatatcaag gaactggctc atatgaccat
    30481 ggtcaatcag ctggctcaag ctgatctggg agtcggagta gactttaagg tttatgatac
    30541 ctcaccagat accgcaacac cattgacaga gatatagaaa gaacgctgag aaggtgttct
    30601 tttta
//
LOCUS       DAVLBN010000023        27006 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLBN010000023 DAVLBN010000000
VERSION     DAVLBN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.023"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..763)
                     /locus_tag="VXC24_001020"
     CDS             complement(<1..763)
                     /locus_tag="VXC24_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493149.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMG"
     gene            complement(920..1165)
                     /locus_tag="VXC24_001021"
     CDS             complement(920..1165)
                     /locus_tag="VXC24_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493150.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(1645..1857)
                     /locus_tag="VXC24_001022"
     CDS             complement(1645..1857)
                     /locus_tag="VXC24_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493151.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(1865..2236)
                     /locus_tag="VXC24_001023"
     CDS             complement(1865..2236)
                     /locus_tag="VXC24_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0493152.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            2994..3314
                     /locus_tag="VXC24_001024"
     CDS             2994..3314
                     /locus_tag="VXC24_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0493153.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILFHLKKEVEIYYQ
                     AKER"
     gene            complement(3603..4073)
                     /locus_tag="VXC24_001025"
     CDS             complement(3603..4073)
                     /locus_tag="VXC24_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0493154.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(4039..4845)
                     /locus_tag="VXC24_001026"
     CDS             complement(4039..4845)
                     /locus_tag="VXC24_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0493155.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(5061..5702)
                     /locus_tag="VXC24_001027"
     CDS             complement(5061..5702)
                     /locus_tag="VXC24_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493156.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(5699..7807)
                     /locus_tag="VXC24_001028"
     CDS             complement(5699..7807)
                     /locus_tag="VXC24_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0493157.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(7859..8146)
                     /locus_tag="VXC24_001029"
     CDS             complement(7859..8146)
                     /locus_tag="VXC24_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0493158.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            8571..8891
                     /locus_tag="VXC24_001030"
     CDS             8571..8891
                     /locus_tag="VXC24_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0493159.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(8944..9516)
                     /locus_tag="VXC24_001031"
     CDS             complement(8944..9516)
                     /locus_tag="VXC24_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0493160.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            9758..10429
                     /gene="sdaAB"
                     /locus_tag="VXC24_001032"
     CDS             9758..10429
                     /gene="sdaAB"
                     /locus_tag="VXC24_001032"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0493161.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            10438..11310
                     /gene="sdaAA"
                     /locus_tag="VXC24_001033"
     CDS             10438..11310
                     /gene="sdaAA"
                     /locus_tag="VXC24_001033"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0493162.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            11332..11964
                     /locus_tag="VXC24_001034"
     CDS             11332..11964
                     /locus_tag="VXC24_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0493163.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            12014..12091
                     /locus_tag="VXC24_001035"
                     /pseudo
     CDS             12014..12091
                     /locus_tag="VXC24_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12357..14207)
                     /locus_tag="VXC24_001036"
     CDS             complement(12357..14207)
                     /locus_tag="VXC24_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0493164.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14249..15406)
                     /locus_tag="VXC24_001037"
     CDS             complement(14249..15406)
                     /locus_tag="VXC24_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0493165.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            15464..16630
                     /locus_tag="VXC24_001038"
     CDS             15464..16630
                     /locus_tag="VXC24_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0493166.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            16769..17095
                     /locus_tag="VXC24_001039"
     CDS             16769..17095
                     /locus_tag="VXC24_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0493167.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            17082..17675
                     /locus_tag="VXC24_001040"
     CDS             17082..17675
                     /locus_tag="VXC24_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0493168.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            17668..18579
                     /locus_tag="VXC24_001041"
     CDS             17668..18579
                     /locus_tag="VXC24_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0493169.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            18642..19706
                     /locus_tag="VXC24_001042"
     CDS             18642..19706
                     /locus_tag="VXC24_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493170.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(19884..20744)
                     /locus_tag="VXC24_001043"
     CDS             complement(19884..20744)
                     /locus_tag="VXC24_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0493171.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(21019..22005)
                     /locus_tag="VXC24_001044"
     CDS             complement(21019..22005)
                     /locus_tag="VXC24_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0493172.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(22277..23752)
                     /locus_tag="VXC24_001045"
     CDS             complement(22277..23752)
                     /locus_tag="VXC24_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0493173.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(23962..24885)
                     /locus_tag="VXC24_001046"
     CDS             complement(23962..24885)
                     /locus_tag="VXC24_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0493174.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(24899..25828)
                     /locus_tag="VXC24_001047"
     CDS             complement(24899..25828)
                     /locus_tag="VXC24_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0493175.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(26147..26367)
                     /locus_tag="VXC24_001048"
                     /pseudo
     CDS             complement(26147..26367)
                     /locus_tag="VXC24_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26321..26581)
                     /locus_tag="VXC24_001049"
     CDS             complement(26321..26581)
                     /locus_tag="VXC24_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493176.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         8344 a         5732 c         4701 g         8229 t
ORIGIN      
        1 atcccatagt atatttttct ttataaagca aaggtaaaac tttataaaaa atatctaagt
       61 caacctcact ctgattctga agcaagtagg agtcaagcaa attttcaaaa atagctaaca
      121 atatgattgg tgtaaagttt ttgtattcac atgtcaagta ttctgagtat cgtgcagatg
      181 atatttcttt tatataactt tttgaaagca agattttttc aaattcatca tctattatta
      241 atcttctatt tccaatccaa gcggtattac cacccaaata agattgtgca aatagcaata
      301 tgtaagaaaa tatgaacgta aatactgaaa gaggtagaat tctatgcgta aaaaaataga
      361 cgataatggt agccaggagt aaagatatct ctcgtgacaa tcgaattctt ttcagcatct
      421 tttttaacag tccgtaaggt tgtccttggc aatattcttg aactaaatta atcggaatga
      481 catctctcac catttctgga aagtagagta agtttatagg ttgaaatctc cagctcccat
      541 cataagtaaa tggatataga accaaatact taaaagattt ttttcttata aacttaatta
      601 tcacaatatg aatgactgtt gcaatgaagt atattaaata taaaagtaaa accgccatca
      661 atatacttac aaaaatcccc ttggaatcaa tcaatggaaa ataaaatatt gcaactagaa
      721 gcgaataaag tcccgctaat aaatatttct gatcatcttt catttaaaac accatattat
      781 ttactaagaa tgcatcaata caatagagca actctgtaag tcaatatttg ataaagcaaa
      841 gctttaaacc cttccccaga cgttagcttt tattcaaccc actacagttg acaaggagcc
      901 caaattattg ataaaaactt tagtcatcat cgtctctata aaaatatttt ctatacactc
      961 ttgataatac caaaattaat gccaatatca taccaagagc tataataata gaatttatta
     1021 gatttatttt agtatatcca atcactagtc caataattgg actagcagac atgcttagat
     1081 ataataaaaa taacaaaaaa tgaatttcac caattcctgc aaaaaaatgt ttcatagcta
     1141 tagttttacg cccataaata cccatcaaat ttaccgtcta cgatatctaa accatatgca
     1201 atggctcctc ctaatgagaa gacttcagca acagtagcca caatattaag agcattagta
     1261 atagttgcca tactaactcc accaatatat cttgttatag cacttagtta cctagataag
     1321 atatccttta gcttgcttcc aaaatttaag tctacaccta taatatgagt tcatattagt
     1381 actgctaaat cctatctata gtaatgtcaa acacctaaat aaagtcatct ctccaattca
     1441 ttcaagaaat gaataaaggc aaaaaatctt taaaataaga aaagtgcata ttatcaggtg
     1501 ttcaaaaata ttgatgatat acgttatata gatagaaaga tttactcaat ctcactttca
     1561 aattgagttt tttcccaacc tcgtttttaa tttatatctt caataaaatc taatgaccta
     1621 gttgatatgt catatggaat aatattattt aatctgtaat ttttttaaaa aacttaataa
     1681 taaatttgct ccactgattg ctatcaatat ttcaattggt aaaaaatagt aattccaaat
     1741 aaaatgagaa atcagcaatg atagaaaaat aacaatatca attttcctgt tgttgacata
     1801 ctctgtaatt ttatgataca ggaatgcaac aataactgaa attaaaacaa tcaacataag
     1861 attattaacc tattctcaat tgattatcac gtcgcccatc ccagccatca ataatattgg
     1921 taaaaatcca atcagctcca gcaccaattc cagcagatgc aatacttcta ataacagtat
     1981 ttgcaaaagc atttccaata tgaattccta atactcctaa acctttaaca atcccagcta
     2041 ccagtgcgga gcgtaatcca taagatgcaa gaactagttg aaggcctcca cctcctgctg
     2101 ctgctaatgc tgcatatgct gcaccagtaa tggctcctgt aattgcccac ctgggtatat
     2161 atatagcccc cccatcaagg tacatcatct cttcttcatc aatcacaaca taattatttg
     2221 gtaatacaag ttccatttat tttctccttt tttattaagc atgcttagga tggtttccta
     2281 acaagtgatc gcaggctttg tttagttacc taaattagac ttccttcctt tatcttattt
     2341 taaatattta aaaccagtta ctgcttgaag cttaacagtt tacttaattc aaataacagc
     2401 taatcactga ttccctgatt ttatcaaata tactaataac aacaattgtg atacgatcat
     2461 cattataaga acaacattta acgaatcaaa gtttttccga gataataata aagcaacagc
     2521 aagcagtatt attactaaag attgaataac tactattact cttaacattt tatcctccac
     2581 taacaactca agctccctta cattatatcg accagcccca tggaaagatt atagctagac
     2641 taatcaatga tataatacat actagaatac aaaatatttt tttattcata ctttttctcc
     2701 tatctttatt ttctacctac atcatacctc ttattaagct catttcaaaa ttacgttaac
     2761 ttttttcacg aaaaggagac aattatgcgt tatgattatg gatagcgctt tcaaattttt
     2821 aaactcctat cccatccttt tatctatatt atgagcgaaa atataataac tgtcaagtaa
     2881 ctaaagtgaa ttttataaaa aaattacaag ccaaatttgt aaagtttaca ctaagccgct
     2941 agggcaatcg tctatcagaa tgtccgttta tttgtcaata atccgagaaa atcttgcaac
     3001 gcttagaagt ctataaaaac tatcaacatt tatatgactt gcgaatagca atcctgctca
     3061 acctttccac actctatcta tacaatcaag ataaaaacat gtgtaagcaa atctgctaca
     3121 ctttactgga ggacgccaag aataagaaaa gctacgatag gctggctatc tgctatgtcc
     3181 gtattgggat ttgtagggat gatgcgaaac ttatccaaaa agggttctcc cttctggagc
     3241 taaccgagga aacttctata ctgtttcatc tcaaaaaaga agtagagatc tattaccaag
     3301 cgaaggaaag ataaaaaagc cgagggattt cctcgactct ttacatatta tttgttcgtt
     3361 agttcttaat accagctatt gttaagccag aagtttttag ctctgccaag ccacatagtg
     3421 tgtttactac tatgtgtcca tgtcaccatg aatcgccgaa cgatttaacg agaaagtatg
     3481 acttttccgt ttatcccaac tcaattatga catttttttc aaaagtcaat atatctcact
     3541 ttttcaacga caagaaagag gctgataatc taccaacctc ttattctgaa cccatcactc
     3601 catcactttt tagcttcatt cgctttctta gcgactgcaa tctggtattc gacttggtca
     3661 ttccccttac cggtacaacc atgagcaatt gtagtcgctc ctatctgatg cgctatttca
     3721 accaattttt tagaaatcag agggcggctc aaggcagata ccaagggata cttttgttca
     3781 taataggcat gtgactgaag agccactagc acataatctg tagcaaattc gtccttaaca
     3841 tcaatgacat aagattctac tgccccaacc ttaagagcct tatcatggat gaaatctaag
     3901 tctttccctt cacccacatc catacaaact gaaacaacat catagtcttt ctttaaccag
     3961 gtaatagcaa ctgatgtgtc caaaccgcca gaataggcca aaattacttt ttctttactc
     4021 atgttctttt ccttctttct atttttcaat ggatgcttta aaggcatcct caatgagttt
     4081 gtctaattcc ccagactcct tcaacttttg aatggtttta tcgactgcct ctttcaattc
     4141 cttgctatct tttttcatgg ctaccgcgta ggaatcatct tgctcttttt caaaattgag
     4201 gtctgcgatt gctaaatcag gattattttc cacaaatccc ttggaaacag gttcttcaaa
     4261 gataacggca tccacttgtc ctgattttaa atctgtgatt aaattcccat ttttaggcag
     4321 agatacgagg gaagaatttt gtagcaaatc tttcgccatc gtctcttgaa tcgaaccttt
     4381 ctgcgctcca acctttttct gcgccaagtc gtttacagac tgataagtag tcaagtcaga
     4441 ttttttgaca atgagtttat tttttgcagt atagtaggga atggaaaagt caaacacctt
     4501 gctccgttca tctgtcttag aaacacctga tatggcaagg tctgcttttc ctgattgaac
     4561 actagccagt acattatcaa aactcatggg agatagttcc aattcgacac ctagttctgt
     4621 tgcgatagcc ttggctaatt cgatatctga acccacaatc tgatttttcc catcaaccac
     4681 tttttgatat tcaaatggag caaaatctgg attgagggct acaaccaatt ttcctttgga
     4741 cttgatggct tcaattccag ccgattgatt gttactacaa gcaaatagta gggggagcat
     4801 cactaaacca aacatcgtca tcaacacctt cttcatctta ttcataacaa agccttcttt
     4861 atgtttattc ttttttattg tataaataat actcctatac tcatatactc atcctttgtc
     4921 aagcctaaat tgaaaaaatt ttcaatttga aacaaaaaaa aacctagaaa tgctacataa
     4981 aatgtcattc ctaggcgtat ttatgctatt tttctctgga aaacatgagt attcagccag
     5041 tcaaaaggag ctgaatgaac tcattttccc tcgcccaatt caatgacacg atgacattgt
     5101 tgggctacat aagcatcgtg ggtcacaata atgactgttt tcccttctcg attcatctct
     5161 aagagaaact tcaagaccaa atctctattt tcaggatcca gcgaacctgt aggttcatcg
     5221 gctaaaatca gctggctggg ttttaagatg gctctagcaa ctgcaattcg ttgttgttcg
     5281 cccccagaca actcggagac cctttgatgc aaagtagctg acaaacctac tctctctaaa
     5341 atctcttcca cctttttgag cttgtctttc ttaggcaatt tcacatattt cagcgccagc
     5401 atgagattgt actcgaccgt ttcatcatca atcagggcaa aattttgaaa cagataagag
     5461 atatgttcac ggattattgt ttgcgactta gcagaattaa ccgctagatt tgtctgacca
     5521 aaaatctcat accgtccgct ataatcacca tctatcaaac ccaataaatt taacaaggtc
     5581 gacttcccac taccactctt accaacaata gctaccaaat ccccctgatc aatcctgaga
     5641 gataagttat ccaaaatcac ttttccccca atggttttgg taatattttt caactcaatc
     5701 ataagatgcc ccctttcaat aactctacta gacttctttt ctccatccta gaagctaagc
     5761 ctagcacaaa tagtatatcc agacatgtaa aacctgcaaa cagtagaagt ggtaagaacg
     5821 catgggcaaa gaaaatcaag actagaagag ggaaactata gcccagcaag agcagaacga
     5881 ggagaggacg gtagcgatcg accagtttcc accccataaa cttcttggta atgatatccc
     5941 tgcgcttcaa taagaaagtt gttactagta agaagtagga aatcatcatg ctaaggagac
     6001 caaacaaagc aaagagtagg ttaaaattcc gaacagcatc tctataagaa tccactttct
     6061 cttgttgaat ggcttgaata gatgaaaatt ttaaataatt tccatctgac aatttctcaa
     6121 ctaactctgt aatctctttt tgatgttgaa ccgtattttc aattttaatc ggattattta
     6181 agccagttgt tgacagggag gctttctcat cccacatcat atcagaatca ttgaccaagc
     6241 taataattgg attggagaga ttttcctttc gcttatcact atatgggaaa aatgaccaat
     6301 ctccttcata ataggcaatc tcgacatcca tctcctctat cgttcgtttt tgctgctctt
     6361 catacttcat cgaatgaaag gcaattaact tccccaagag ctgattttta tcttcttcac
     6421 ctttcgtact tgctggcatc aaaataactt ttttaatacc ggtatctggt agcttgaatc
     6481 ccttgctctt tagaaaattg cgattggcat agtaaacatc caccgtatct gttaactgat
     6541 attgctgaat ctgttctgat tggacaaaat tttttacagg aagactgcta ctctgcacat
     6601 agcccgcctg cgttttttct accaaatcct gataaaatcg atagaaataa tctgtagatt
     6661 tccctgaccc tgctagctct tcttgccaca gattatcatt gagtttgaag gtttctaagg
     6721 tcaggtaatt accttgactt acccactgtt gctgataagc aagttctttg ttttcttgtt
     6781 ctaaacttct gcccacccca atcagtaagg ccgtcagtaa aatagttgtc cctattttca
     6841 tcacataatt gaagataaga ccaaatttga aagatgaaaa acctttcagc agagagctga
     6901 ttgtcatttt ttggattaag aggtaagtca accaactgat aaagagataa agctgcaaca
     6961 gcaaaaaatg agacaaccac agcataggaa acaaatcttt tggcttataa tcaagcaaga
     7021 aaaacacgcc tagattgatc acaagagccc cacctaggag gaggtaaagg ttgcctttta
     7081 caacatcagc taaaacagcc ctatcttgaa aaccaagtaa tttttgtacc ccaactcttt
     7141 tcatctccat catcggttga tacactgtca ctaacacaag aagcaaaata gccaagacaa
     7201 aaacaatggc agataaaagc aaatctcgat ttatgacttc cactgcactt ttgtaggtcg
     7261 gctctagcaa ggtagcctgg tctatcttga aaaaatcgct ccatttctgt acaatcctat
     7321 ccttgtccat ctcttgtgta gaagttatcg tatagcgacc atttaaacta cgagatgtat
     7381 ccttgatata ggtttgaaaa gtcataagct gaataggttt ggcttttaga aaggtcggaa
     7441 tcgtaccaag tttattggaa atttctttat tactatagac tccttcacca tctgtggtaa
     7501 aatcaagaga agaaatccca aactcttggt aggggaaggt atctttatca aaaacaccag
     7561 acttgaccac ctcatcacca ctgtctgttt tgatgatgga gactttatac tcctttgata
     7621 catcctcaaa aaatcgaaga acagacgctg caggttcgtt aatatctttc aaatacaaat
     7681 ccaaagaatc tacagtcttt cccatttctt gaatccgaac cacttctcgt gtatagttta
     7741 cattaaaaac aaaaaaagtg gtacacagaa gcaggagtaa catacagaaa ttactgattt
     7801 ttttcataaa agtgcctcca ctacagtttt ccctctccaa ataggagagg gaagaatttt
     7861 actcaaatcc atagaaatat tccattcctg ttggcggaat cttggtgagg gaagctctag
     7921 cccatgcctc aggttttgca taatccttag aggttctacc cccatgtcta acagttgctg
     7981 tatgatatcg agtagaatgt aagtaatcag aatatccaaa agttcctgtc caacctactc
     8041 catagttcca ttgaccaccc tcaacccata ctgctaaagc atttgtagta gcaagtatac
     8101 cacataccat taaagatgca acaccaattt taactaattt tctcatgatt tatttctcct
     8161 attatcgaga gctgttccgt aaaaacagct atagtaattt atcaacaagt atcgtagtcc
     8221 attggactca ccttccttct atctcatttc attttttaac aacgaactta ctcttaaccg
     8281 ggagaatggt gcgcttctgt atcaggtcct tgaacaacca gagtagtatt aagcacactc
     8341 taactattac tcaagaatca gtccaataaa caatatggat agcgctttca aatttttaaa
     8401 ctcctatccc atccttttat ctatataata agcgaaaata taataactgt caagtaactg
     8461 aagtgaattt tataaaaaaa ttacaagcca aatttgtaaa gtttacacta agccgctagg
     8521 gcaatcgtct atcagaatgt ccgtttattt gtcaataatc cgagaaaatc ttgcaacgct
     8581 tagaagtcta taaaaactat caacatttat atgacttgcg aatagcaatc ctgctaaacc
     8641 tttccacact ctatctatac aatcaagata aaaacatgtg taagcaaatc tgctacactt
     8701 tactggagga cgccaagaat aagaaaagct acgataggct tgctatctgc tatgtcccta
     8761 ttgggatttg tacagataat gctaaactta tccaaaaagg tttctcactt ctggagctga
     8821 ccgaggaaac ttctatgctg tctcatctca aaaaagaagt agagacccat tatcaaccaa
     8881 agaaattata aaaaaagtcg agggagctcc tcgacctttt acatattatt tgttcgttag
     8941 ttcttaatac cagccattgt taagccagaa gtttttagca gcagtccatg aaccgtaacg
     9001 tcctgcaacg taggcatctg ctacacgttc ttggttttca gctgagtagt caccgttcag
     9061 gtatgaatct gttaattggt aacgtccgat ataacgtcca tttgtagctg tatagctacc
     9121 acctgattct ttttgagcga tccattcttt ggcttctgct tcagatccgc ttacagttga
     9181 aacaactgtt tcacttacta ctggagctga aacagtttca tcttgagcgg ctggtgccgc
     9241 ataagtagct ggcgctggtg ttgcaacagg cgctacaggg ccatcgataa ccaactcttg
     9301 atcaacataa atcaaatgaa tgttatcaat gtggttgttt tctgccaatt tttcaactgt
     9361 tgtgttgtga gtttcagcga tttctgaaag tgtatcacct tctttaacag tgtaagttga
     9421 tgattcttga gcagatacaa atgatggagc aaatactgca aacaaggcag ctactcctgc
     9481 aagagttgct ttaatctttt tagttattga tttcatattc gaaaattctc cttctttcta
     9541 tagttctatc atacccttta aatattaccg tttcttgaca cttttatgta gaaatattac
     9601 aaaattattt tttatttccc taaataaggt gttttttgtc ataaaagata ctatttttat
     9661 gctatttgag gtattagaaa ggttttcatc cacaattaaa gccaagcccc tcattctttg
     9721 atataataga gataagaatt tttataaggg gaaactgatg aaatcacttc gttttcaatc
     9781 tgtctttgat atcatcggac cagttatgat tggcccatct agtagccata ccgctggtgc
     9841 tgttcgtatt gggaagattg tctcttccat ttttgatgat actccgacag aagttgaatt
     9901 ccaacttttt aactcatttg ccaagaccta tcgtggtcac ggaacagacc tagcccttgt
     9961 tgcaggtatt ttaggaatgg atacagatga tcctgaaatt ccaaatagtc tggaaattgc
    10021 ccacaagcgt ggtatcaaga ttgtctggac cattcagaaa gacagcaatg cccctcaccc
    10081 taacaccact aaaattactg ttaaaaatgc ccacaagacc atcagcgtga ctggtatttc
    10141 tatcggtgga ggaaatattc aggtaaccga actcaatggt tttgccgtct ctctcaatat
    10201 gaatacaccg actatcatca tcgttcatca agatattcca ggtatgattg cccttgttac
    10261 agaggcgctt tcccgctatg gtatcaatat cgcccagatg aatgtcactc gtgaaaaagc
    10321 tggtgaaaaa gccattatga ttatcgaagt tgacagtcgc aactgtgatg aggctatcga
    10381 agaaattcga aaaatccctc atctccacaa tgtcaatttc tttaaatagg aggaagcatg
    10441 ttttattcta tcaaagaatt ggtcgagcaa gcagatctag actttcaagg aaatgtcgca
    10501 gaactcatga ttacaacaga gtttgaattg accggtcgcg aacgtgaaga agtcttcctt
    10561 ctcatggaac gcaatctgga agttatgaaa gcctctgtcc aacttggcct caatgaaaat
    10621 aaatctcgta gtggcctgac aggtggagat gctgccaaat tggatcacta catcgaaaac
    10681 ggaaaaactc tgtcagatta cacgattctc tctgctgccc gaaatgccat cgcagtcaat
    10741 gaacacaatg ccaaaatggg cttggtctgt gccactccaa ccgctggaag tgctggctgt
    10801 ctgccatccg ttctcactgc tgctattgaa aaattagacc tcagccacga gcaacaattg
    10861 gatttcctct ttgctgctgg tgcctttgga ctagtcatcg caaacaatgc ctccatctca
    10921 ggtgctgagg gtgggtgtca agctgaagtt ggttcagcct ctgctatgag tgctgccgcc
    10981 ttgactctgg ctgcaggtgg aacaccttat caggccagtc aagctattgc ctttgtcatt
    11041 aaaaatatgc taggcctcat ctgtgaccct gttgcaggtt tggtcgaagt tccctgtgtc
    11101 aaacgtaatg ccatgggagc tagctttgct ttcatcgcag cagacatggc cttggcaggt
    11161 atcgaatcta aaatccctgt ggatgaagtg atcgatgcca tgtaccaagt aggagcaagc
    11221 atgccaactg cctttcgtga aacagctgaa ggtggactcg ctaccacccc tactggtcgt
    11281 cgcctccaaa aagaaatttt cggagaataa gcttatcaaa taggagaaac catgacctct
    11341 atcacagcga tttttttcga tttggatgga accctcgttg atagttctat cgggattcac
    11401 aatgccttta cctatacctt taaagagctg ggggtgccta gccctgatgc caaaactatt
    11461 cgtggtttta tgggaccacc tctcgaaagt agttttgcga cctgcctgtc caaagaccaa
    11521 atttctgaag ccgtgcagat atatcgttct tactataagg caaaaggcat ctatgaagct
    11581 caactctttc ctcagattat agacttgctt gaggagttat cgagcagtta tccactctac
    11641 atcaccacga caaaggatac atctactgct caagacatgg caaaaaactt ggaaatccat
    11701 catttctttg atggcattta tggttctagc cctgaagcac cccataaggc agatgtcatt
    11761 caccaagcct tgcagacaca tcaactagca ccagaacaag ccatcatcat cggagatacc
    11821 aagtttgata tgctgggagc tcgagaaaca ggtattcaga aattggccat cacttgggga
    11881 tttggagagc aagcagatct actaaactat caacctgatt atatcgctca caaaccctta
    11941 gaagttttgg cgtattttca atagcataga ctgggtaaca attccatttc agaagaaaat
    12001 gaagtaatac tcaatgaaaa tcaaagagca aactaggaaa ctagctgcgg gctgctcaaa
    12061 acactgtttt gaggttgcag atagaactga cgaagtcaga tcaaaacact gttttaaggt
    12121 tgtggatgga actgacgaag tcagatcaaa acactgtttt gaggttgcag atagaactga
    12181 cgaagtcaga tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
    12241 tatacggcaa ggcgacgttg acgtggtttg aagagatttt cgaagagtat aagtctctac
    12301 ataataaaac gcatattacc aaggttgtgt aactggatac tatgcgtttt tcttttttat
    12361 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
    12421 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
    12481 ccaacgaaaa tcttatccat aacttgatta tcaacgagtt cggttgatac caagagttct
    12541 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actttcagtg
    12601 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
    12661 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacggcta
    12721 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
    12781 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
    12841 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
    12901 tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt atctgtcgaa
    12961 atcataacca tcttagacac tttagcttca tcaacagcct tagcaacatt gtaagttcca
    13021 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
    13081 gcagccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
    13141 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
    13201 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
    13261 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
    13321 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
    13381 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
    13441 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
    13501 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
    13561 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
    13621 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
    13681 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
    13741 aaggttcgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
    13801 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgatgaaa
    13861 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
    13921 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatgctcgcg
    13981 ttcaaccccc aaaaaccaat catcaattga tagaacagga aggccaaact cgtatagata
    14041 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaatgatg
    14101 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
    14161 aaaatttcca ccagatcaat cacataatct gttagttttt tattcataga aatctactcc
    14221 tccttaaaag agttttacta tattgttatt atagcatatt ttgatttatt tggcttattt
    14281 tatccaaata aattattgtt ctcttgtact ccttcttcca tttaaatcct ctaattaaac
    14341 ctacaatcgt cccaaagcca taagcaaagt gaatggaaaa taaaagaaag ggcatcacaa
    14401 ttagaaatcc atttttatgt tttaataaag tcagcaaagt gagtaatgac aaaagtagaa
    14461 aataggcacc taatagtaaa gttatgaata cgaatgtgat cggtaacaat gctagactaa
    14521 acacaagact caaaacaaat aaacaaggaa catagtgaaa taatgataaa cacttaaact
    14581 gaacatgact tgtcaagcca atccacaaac catttgaata cttttgatgc agcattttct
    14641 tgaatgttgg tcgaatatac tgataagata gaatacttgg gctatagcgg attttataac
    14701 catgttctcg aattctataa tgaatatcat tatcttcagt tcggccaagt tgctcattta
    14761 ctaaaccaac cttctggaaa acctctcgtt tatacatccc atgaaaaata gaagaaacat
    14821 atctatcctc ggaactattt cgataattgg caatgctact gccaaacata ttttcctcaa
    14881 caagatgcaa ggtctctgcc cattttcctt ttccttcgac aatcgtcggt ctaggccccc
    14941 cacagacaaa ttcaccttgt tgaataatag ccacattgtt cattacaaaa ctctcagtaa
    15001 cttttgaatg agcatcaatt tttaaaataa ggtcccctac agaatgttta actcccaggt
    15061 taaaaccact agcttgattt ttcttaggat tgttatacaa tctaattgag ttaaactctg
    15121 tatcttcctt tataaattgc tgaatgatag ctgtggtccc atctgtggac atagcattta
    15181 taaatagaat ttcaatatcc tctttaggat aggtttgatt ttttaagtct tcaattagac
    15241 caggcagata tttttcttca ttgtatgcac tgattacaat ggatacgaga agactttcaa
    15301 cattttgagt cactactact ctcctgaatt tttccttcca ccattctatc ataattttca
    15361 agactttccc atttttatct tgaaagccag aaaccttact tgacattata gtgaaaaagc
    15421 cttaaaataa gctgttatta aaatcagcta gaagaggtat tatatgaaaa agcaatcact
    15481 cttttttgtt ccaggtatta tcctgattgg tgtttccttg cgaactcctt ttactgtttt
    15541 acccattatt ttgggaaata tttcgcaagg tctggaggta gaagttagtt cgcttggtgt
    15601 cttgaccagc ctgcctctcc ttatgtttac cctcttttca ccattttcta cccaactggc
    15661 tcagaaaatc ggcttggagc atctcttcac ctacagcctc ttcttcttga ccatcggctc
    15721 acttattcga ctaatcaatc tgcccctgct ctatctagga accttgatgg ttggggcaag
    15781 tgtcgcagtc atcaatgtcc tgcttcctag tcttatccaa gccaatcaac caaagaaaat
    15841 tggttttctg accaccttat atgtaacgtc tatggggatt gcaacggctc tggcttccta
    15901 tctagctgtg cccattacac aagccagttc ttggaaagga cttatccttc tcctcacgtt
    15961 actctgtcta gcaacttttt tggtctggct cccaaatcac cgctataatc atagactagc
    16021 tccacaaacc aaacaaaaaa gtcaaataaa ggtcatgcgt aataaacagg tttgggcaat
    16081 tattatcttt tcaggttttc aatccttgat cttttacacc gtcatgacct ggttacctac
    16141 catgtctatc catgcaggtc tatccagtca cgaagctggc ttgctgactt ctatcttatc
    16201 tctgattagc attccttttt caatgaccat cccaagcctg acaaccagtt tatctactcg
    16261 caaccgtcag ctcatgctca ctctggtttc actagctggt gtggtcggca tttccatgct
    16321 ctttttccca atcaataatt tcatttactg gcttgccatc catctcctca tcggaaccgc
    16381 aaccagtgcc ctcttccctt atctcatggt caacttttca ctcaagacaa gcgcccctga
    16441 aaagacagcc caattgtccg gcctatctca aacaggaggc tatatcctag cagcctttgg
    16501 gccaaccctc tttggttaca gttttgacct gttccactct tgggtaccat ctgtagctgc
    16561 cctcttgctc atcgatatcc tgatgactgt ggccctcttt acagtggaca gagcggataa
    16621 gatcctttaa acttctagtt ttagctagaa gttttttata tataaaaatt ttacacattt
    16681 ctcttgacag ggctttcttt tagatgtaca atgtatgtgt agaaaaatta tatataaaaa
    16741 tcttacacat tagaaaagga ggtttcccat gtactttcca acatcctctg ccttgattga
    16801 atttctcatc ttggctgtac tggagcaggg tgattcttat ggttatgaga ttagccaaac
    16861 cattaagctg atcgctaata tcaaagaatc cacactctat cccattctca aaaaattgga
    16921 aggcaatagc tttctgacaa cctactctag agagttccaa ggtcgcatgc gcaaatacta
    16981 ctccttgaca aacggtggta tagagcagct cttgacccta aaagatgaat gggcactcta
    17041 tacagacacc atcaatggca tcatagaagg gagtatccgc catgacaaga actgaatacc
    17101 tgactcagct agaactctat ctcaagaaac tacctgaagc tgaccgtatc gaagccatgg
    17161 actatttcag agagctcttt gacgatgctg gagtcgaagg agaagaagaa ctcatcgcta
    17221 gtttgggaac tcccaaagaa gcggcccacg aagttctatc caatcttctc gataaaaaaa
    17281 tcaatgaagc acccgctcaa aaaaataacc gacaaatttt acatatcgcc ttgttagccc
    17341 tccttgcagc acctatcggc attcctctgg gaatcgccat cctcgtgacc ctgttcgcaa
    17401 ttcttgtagc cgctttgact gtcattctgg ctttctttgc agtttccata ctgggtatca
    17461 tcggcggatt cctattttta gttgaaagtt tcactgtcct cgcccaagcc aaatcagcct
    17521 ttatcttgat ttttggttct ggtttactgg ctatcggtgc ttcttcgcta gttttacttg
    17581 gcatttccta tgcaactcgc ttcttcggtc tactcattgt tcgtctggta caatttgttc
    17641 ttaaaaaagg aaagagaggt aatcagcatg cgtaaatgga caaaaggatt tctcatcttt
    17701 ggtgtggtga ctaccgttat cggctttatc ctgctttttg taggtatcca atctgacggg
    17761 attaagagcc tactttccat gtccaaagaa cctgtctatg atagccgtac ggaaaagcta
    17821 acctttggca aggaagtcga aaacctagaa attactctcc accaacacac gctcaccatc
    17881 acagactctt tcgatgatca aatccacatt tcttaccatc catctctttc tgctcaccat
    17941 gatcttatca ccaatcagaa cgatagaact ctgagtctca ctgataagaa actgtctgaa
    18001 actccgtttc tctcttctgg aattggtggg attcttcata tcgcaagtag ctactctagt
    18061 cgttttgaag aagttattct ccgactacca aaagggagaa ctctaaaagg gatcaacatc
    18121 tcagccaatc gcggacaaac caccatcata aatgctagcc ttgaaaatgc gaccctcaat
    18181 acaaacagct atatcctccg aattgaagga agtcgtatca aaaacagtaa actcacaacg
    18241 cccaatatcg ttaatatctt tgatacagtt cttacagata gtcagctaga gtcaacagag
    18301 aatcacttcc acgctgaaaa tatccaagtc catggcaagg ttgaactgac tgccaaagat
    18361 tatctcagaa tcatcctaga ccagaaagaa agccaacgaa ttaactggga catctcaagc
    18421 aactatggtt ctatcttcca attcacaaga gaaaagcctg aatcaagagg tacggaatta
    18481 agcaaccctt acaaaactga aaaaaccgat gtcaaggatc aactcattgc gagatctgat
    18541 gataatattg atctaatatc cacaccaagc agacgttgac aaaaacgctt acatttgcta
    18601 ctatggaaac atatttatct aactaaaaag gaggttctac catgaaacaa gaatggtttg
    18661 aaagtaatga ttttgtaaaa acaacaagca agaacaagcc tgaagagcaa gctcaagagg
    18721 ttgcagacaa ggctgaagaa acgatagccg atctcgatac accaattgaa aaaaatactc
    18781 agttagagga ggaagtccct caagctgaag tcgaattgga aagccagcaa gaagagaaaa
    18841 ttgaagctcc tgaagacagt gaagcgagaa cagaaataga agaaaagaag gcatctaatt
    18901 ctactgaaga agagccagac ctttctaaag aaacagaaaa agtcactata gctgaagaga
    18961 gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga gccacttctt atcagtaaat
    19021 ctttagaaag tccttatatc cccgaccaag ctccaaaatc tagggataaa tggaaagagc
    19081 aagtgcttga tttttggtct tggctagtgg aagcgatcaa atctcctaca agtaagttgg
    19141 aaacaagtat cacacacagt tacacagcct ttctcttgct cattctgttt tctgcatctt
    19201 cctttttctt tagtatctat cacatcaaac atgcttacta tggacatata gcaagcatta
    19261 acagtcgctt ccctgagcag ctagctcctt taactctttt ttctatcatc tctatcctag
    19321 tagcgacaac actcttcttc ttttcattcc tcttgggtag tttcgttgtg agacgattta
    19381 tccaccagga aaaggactgg acgctagaca aggttctcca acaatatagt caactcttgg
    19441 caattccaat cttcctcact gctattgcta gtttctttgc tttctttgat agcctacgat
    19501 ttacagccct cttgtgtgtg attagcattg gaatcattct gcttgccagt ctccatatca
    19561 ttacaagacc aagtcaagca agtgaaaccg actccttcta tcaattattc ttgtctgtcc
    19621 ttgtgaacgg agttattatc ctcctcttct ttgtagctga agtggcactg attggagatt
    19681 atcttcgtat cttggccttt ctttaaactt catactcttc aaaaatcaaa ttcaaaccac
    19741 gtcagcttcg ccttaccgta ctcaagtaca gcctgcggct agcttcctag tttgctcttt
    19801 gattttcatt gagtagcaat cctgtcatcc ttggcaggat tttttctatg tcaaaaaagc
    19861 aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa atctttgtct
    19921 aatatgggtt gcacttctat ttgattggcg tctagttggt ggtaaaaaga tgggggtaat
    19981 acctctaaga attttgcata gtccaagcga gcaatggctt catagtcttc tggtttagag
    20041 ccatctcctg tgatttgaac caagtcaatc tcccactgga cttccttatc caccaattgc
    20101 tcaatatagg ctgcaggaac aaacggttct ctcggtaaaa ctgtcttgac tccttgagct
    20161 agatggtaaa cgccatgcac ttttccttct ccatcctgat agaaggaaac tctctcaaag
    20221 taggcatctg tctcttgaac cgcacgcaca cgcgcttcaa actgagccaa gccatctgcc
    20281 tctaaaaagc ttttcaagtt ctcacgacta aagaaaatag gattaaaaat tccttggcaa
    20341 atcgtaaaac gagctacagg gtctgctaga taggcttgaa tacttgcttg gaaataagct
    20401 tcaaaatcaa aaccatctag cccttcaata tcagtccctg tataagcaag caaagcatct
    20461 aaaaatgact tgataatctg ccagtctgtc tttgttagta ggtcaggaag atcgacacgg
    20521 taagcctttt gaccatcagc ataactgacc ttaaagagaa attgtgattg ccccactatc
    20581 gcacactcga tatattcgag acgattaaga ggctgacgga gatagactac atcatagcta
    20641 tgtgactcca aaccgtctag caaggccaag atcgacttgg cattcaaaat ctcttgttct
    20701 cctaaaatgc tctgtttatt tggaataaaa aatgttttcg ccataactgg actcctttga
    20761 aatcgtttac atacagtata ccttattttt ctgaaagata caaaaacaaa ctttatactc
    20821 ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgccg tagatatatg taactgactt
    20881 cgtcagtctt atctacaacc tcaaagcagt gctttgagca gcctgcagct agcttcctag
    20941 tttgctcttt gattttcatt gagtattaga tttttgagta caaagcatag aaaaacagcc
    21001 cctaaggact gtttgatctt atacagtagc tgcctgatcc aagctttcac cgatagcggc
    21061 taggcgctca atcacttcag cttgtgtcaa ttcatttttt gaaacatagc ggttacgtgg
    21121 gtgaacacgg cactcgtgtg agcatccacg aaggtacttg tcttcatttt cttctgatgt
    21181 caagatacga cggttacaga agggatttcc acagttgaca taacgttcac atggtgttcc
    21241 atcaaaccag tctttcccta cgatagttgg gttgacatgg ttgacatcaa cggcaatacg
    21301 ctcgtcaaag acgtacattt tcccatccca aagctcacct tgaacttctg ggtctttacc
    21361 gtaagttgcg attcctccgt gcaattggcc gacatctttg tagccttcac ggaccatcca
    21421 gcctgagaat ttctcacagc gaacgccacc tgtacagtaa accacgacac gcttgtccat
    21481 gaatttttcc ttgttatcac ggacccattg tggtaactca cggaagttgc gaatatctgg
    21541 gcgaatagcc ccacggaaat gtcctaggtc gtactcataa tcgttacgtg tgtcaaggac
    21601 aacggtatct ttatcaagaa gcgcttcttt gaactctttt ggagacaagt aagcacctgt
    21661 tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct tccaaaccaa ggtggacaat
    21721 ttctttcttg tagcgaacaa acatcttctt gaaggcttgt tctctttctt cgtcaatctt
    21781 gaaccagaga tcttccatac ctgggaggct gtgaacgtag tccatgtatt tttgagttgt
    21841 ttcatagtca cctgaaactg ttccgttaat tccctcgtca gcgactagga tacggccttt
    21901 aaggccgatt gatttacaga aagccaagtg gtctgcagca aattgctctg cattttcaat
    21961 tggagtataa aggtagtaaa gtaagacacg aatatctttt gccataagat ttgttctctt
    22021 ttctattctt aaattttcta aattttttat ttatccatac tagtatacct gcttgagaaa
    22081 acgaatgcaa tttatttgac tggaaattgt agagggttct cgaaatttcc tgaatggtta
    22141 aaataaggac aagagaaaac atggatatct atatccttgt gccaaaaaaa ccactgccct
    22201 ccccagacca acctgaggaa agcagtgatt cttattttag gagttaggaa tgaatacacg
    22261 aaatcaattt agctgattat tttttgtttt tcaagaattc atcgtattgt ttttgcattt
    22321 cgttcaatac tttttcgtag gcaccttcag atttcaattt ttccatcaat tctggaatag
    22381 ctttatctgg gtctacagta ccagtgttga tagctgtatc aaattgttgc attgtgttag
    22441 caatagctga gatttcagat ttcacattgt cagtattgaa gataaatcca agcgctggag
    22501 attctttagc ttctgccaat tctttcttag aattttcgat ttgttggtct gtaacgtttt
    22561 cgttgatgta aaggatccag ttgttaccag tgttccatcc acccatgtga gtgtttcctt
    22621 tgtagccatc aagaacgcga acacggtttt ctttaccttc aattttttcc cagttcttgc
    22681 cttctggacc gtaaacaaga ccgttcaaga gttctggatt cgtattcaag aggttcaaga
    22741 tttccattga tttttctttg ttcttagagt tgtttgagat gacaaagtta gcaacttgtg
    22801 ttgtttggtt tttcttgatg aagttagtaa ttggtttgat ttggatatct ttgttggcaa
    22861 cacgtgaaag caagctgtta ccgtagtcag ctggtcctac tgtttcttca cgaacgaacc
    22921 aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc gacatctttt ggaatgtagc
    22981 cagcttcata gaatttgtga agagtcttca agtgttcttt gaaacgaggc acttcgtaac
    23041 ggtttacaac tttagtagta tcgccttcaa ggtcaataac gaatggaagc ccgtttgcta
    23101 ctgggtagtc aaaattatca gatgggatga aaactttacc aatagcaaat ggtactacgt
    23161 ctggagcttt ttctttgatt tgtttcaaga ctggctcaag agtttcgtaa gaagtaacac
    23221 ctgaaatatc gataccatat ttggcaagga gagttccgtt gaaggcaaag ttttgagatg
    23281 atgctacgtt ggctgcaact ggtacagcat aaatcttacc atttacagta ttacccttga
    23341 tataagctgg atcaagtgcc ttgtaaaggt ctttaccttc ttttttgtac aattctgtca
    23401 agtcagcata agcacctttt tgagcattta caatatagtt atctgcaaag gcgatatcat
    23461 agttttcacc agatgatgtg ataactgaca ttttcttacc atagtcaccc cagccaaggt
    23521 attggatatc caatttggca ccaacttttt cttcgatgat tttgttggca tttgctaaca
    23581 attcatccaa gttatctggt ttgtcaccga tttggtacat tttgataaca ggtttgtcac
    23641 ctgaatcagc agctttttta ctgttacctg tcaagttgcc acaagcagca agacctgcag
    23701 ccaaagcgac tacactagca gatgcaaaag catatttttt ccagtttttc atgataaaaa
    23761 ctcctttttt tatttttaaa cttataaaca atgtaatgat cttatactca atgaaaatca
    23821 aagagcaaac tagaaaacta gccgcaggct gtacttgagt acggcaaggc gacgttgacg
    23881 cggtttgaat ttgattttcg aagagtatta acttcacaca agggaagttg ggaactgaga
    23941 aatgttattt ctcaataagc actattcttt cacaccaccg atagtcaaac cttttacaaa
    24001 gtagcgttgg aaaaatggat acaaaatcgc gattggaagg gttgcaacca caaccatggc
    24061 catacgacct gtttctttcg gtagagcaac tcccagttga ccagtcaagc cgaccgcttt
    24121 ggcaatgtag tccatatttt gttggatttg catgagcaaa tattgcaatg gatacaagtt
    24181 gtcactcttg atgtaaagaa gggcgttgaa ccagtcattc cagaaaccaa gagctgttaa
    24241 gagcgtgatg gttgcgatac ctggtagtga caatggcaaa cagatttgga agaaaatccg
    24301 ggcttcactg gcaccatcga tacgagccga ttctagaatg gcttctggaa tggtcttctt
    24361 gaagaaggaa cgcatcaaga tgatgttaaa tggtgagaga agcattggaa caatcaaggc
    24421 ccaaacagta tccccaagct gaagcacacg agtcaccatg atataacctg gtaccaaacc
    24481 agcgttgaac aacatactga gcagaacgaa gatggtaaag aatctgcgat acttaaaggt
    24541 tgtccgtgaa atagcgtagg cataggttgt tgtgataaag acatttgtca atgtcccaac
    24601 tacggttaca aagacagaga tgaagagggc ttgtaggatt ttatccttaa actgtgccaa
    24661 aaactcaaaa ccgtctaagc caaattggga tgggaagaag ctatagccgt attggaggag
    24721 gcttttctcg tctgtcactg aaataatgat aacgaataca aaaggtagga tacaagagag
    24781 ggcaatcaaa cccgaaatga tactgaagaa gatatctgct ttcttactga aggagtgaat
    24841 gccgacatta tcaatttttt cttttttaat tttctttttt gccatattct cctcctttct
    24901 agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa gtttgatagg ataaccagaa
    24961 tcaaaccaac aacggattgg taaagaccgg ctgctgcagc cataccgata tctgctgtct
    25021 gagtcaaacc attaaagaca tatacgtcca aaacgttggt tacattgtaa agctgaccag
    25081 cattgtgtgg gatttgatag aagagaccaa agtctgcgcg gaagatattt ccgactgcaa
    25141 ggatggtcaa tacagttaca agcggagtca actgaggaat ggttacgttg cgaatacgtt
    25201 gccacttgct agctccgtcc actgtcgctg cttcgtagta ggttggatca attcccatga
    25261 tcgtcgcata gtacatgaca ctgctatatc caaagccttt ccaaatacct aggaaaagta
    25321 ggagataggg ccagatgccc aggtcagcgt aaaaattgac ttctttgaga ccaagacttt
    25381 ccaatagatg attgaacacc cctttatcaa tatttaggaa ggcatctgta aagaaactga
    25441 tgataaccca agacaagaag taagggaaca acatagaagt ttggaaaatc ttcaccattc
    25501 tcttagaacg gagctcgctg aggataatgg caatccctac agatacaact aaacctagaa
    25561 agataaagcc aagattgtag aggacagtat ttcgtgtgat aataaaggcg tctcttgaac
    25621 taaataagaa tctgaaatta tcgagtccga cccatttact atttatgata ctatctatga
    25681 aaccattact ggtcatgtgg tagtctttga aggcaaccac gttcccaaat actggaatgt
    25741 aaaagaatag aatcaaccag agtgtccctg gcaaaaccat caagagaaag atccagttgt
    25801 ctctcaatgt ttttgaaaac tttttcataa tttcctccct ttttattttg atatccatct
    25861 aaaaattctt ttttagactt ttgataacga ttacattatt agtatactcc tatttgcagg
    25921 ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt atgtagcaga tttaaaactt
    25981 tatcaccact atcaaacaaa tgtcctaaat caattgttta ttttatctct attagcccag
    26041 tgatggcgtc actctgttat aagcatccaa caacggggta tactgaaaaa tctccagact
    26101 agggaactca gagatagttc ctaatctgga gatttttaat atgttattag gcgtttgctt
    26161 tcaacttagc aataacctct ttaagattat caatcacctc tgcttcagta tgctcagagc
    26221 tttttcatct gccaagaaca aaactgcttt ttgaagttct ttttgagagt tttcaaggac
    26281 atccttatct actgtttcaa ggtttgagtc tttaagaagt ttacttaatt ccttggctaa
    26341 tttcttgagt ttgatttgca gactcatctt ctcctgctgt ttctttgccc gctgtttgtc
    26401 ctccatcctt agttgctgac tggctttcct taatggactc tagggaagca atggcatctt
    26461 tgactgtttg caaaatatca cgtaaacctt gctctgtcaa actatcatct gcaaaagctt
    26521 tcttagcctc tgccaaaacc agacgtgctg aatctgtggt aggattcgat acacctgtca
    26581 atgatctcaa aagattttct aaggtttgag tctgcttact aatactagac taaaatcaaa
    26641 aagcattata taacagtgat atgaaatcaa ctaaagaaga aatccaaact atcaaaacac
    26701 ttttaaaaga ctctcgtaca gctaaatatc ataaacgcct tcaaatcgtt ctatagtaaa
    26761 atgaaacaag aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    26821 gaagtagatg tgtactattc tagtttcaat ccattatatt tcgtctgatg ggcaaatctt
    26881 aataaagaga ttatagagct tttatagtga tttgaaataa gatgtgaaca actctatcag
    26941 gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt ataaattcaa
    27001 tacact
//
LOCUS       DAVLBN010000024        25895 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLBN010000024 DAVLBN010000000
VERSION     DAVLBN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.024"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(355..717)
                     /locus_tag="VXC24_001050"
     CDS             complement(355..717)
                     /locus_tag="VXC24_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0493177.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            complement(760..987)
                     /locus_tag="VXC24_001051"
     CDS             complement(760..987)
                     /locus_tag="VXC24_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493178.1"
                     /translation="MPKMTLRAIRTNYNLSAKEVADKLNIHQQTLLKYEHDSSKIPMD
                     LLDKLARLYNVEKDFIFLGKKYELNHNLGEV"
     gene            1060..1266
                     /locus_tag="VXC24_001052"
     CDS             1060..1266
                     /locus_tag="VXC24_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493179.1"
                     /translation="MTDYQLEASLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVKIDRSNSDQITFLIK"
     gene            complement(1491..1661)
                     /locus_tag="VXC24_001053"
     CDS             complement(1491..1661)
                     /locus_tag="VXC24_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493180.1"
                     /translation="MKEKLNEFLKFRSQFTKREWIEINQVVEARLNEKADQLKLDDSD
                     VEIISKRLGRSI"
     gene            1863..2549
                     /locus_tag="VXC24_001054"
     CDS             1863..2549
                     /locus_tag="VXC24_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0493181.1"
                     /translation="MKTTIVSFSGASRQTVKFEYPEYCPHCGKNISPEMIYVSDSEDS
                     YSSGDARFVVTFRCSRSTCKKYFAVEYIFTSTSKPCIIAEYSYRPPIKVKLPENIEKV
                     SPVFVEIYSQATIAEREALDQIAGVGYRKAAEFLIKDYAISKNPSDEGKIKSIMLGQV
                     ISTYLNDFPKIQVLAKSVAWIGNDETHYVRRHDGKDIDDLKKFILSATQFIAADYDAD
                     EALIFTSSSD"
     gene            complement(2504..2641)
                     /locus_tag="VXC24_001055"
     CDS             complement(2504..2641)
                     /locus_tag="VXC24_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493182.1"
                     /translation="MNELERTALNEILRTVTYIAEKVDEIDSKISQSEEDVKINASSA
                     S"
     gene            complement(2718..2993)
                     /locus_tag="VXC24_001056"
     CDS             complement(2718..2993)
                     /locus_tag="VXC24_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493183.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKLNVA"
     gene            3166..3957
                     /locus_tag="VXC24_001057"
     CDS             3166..3957
                     /locus_tag="VXC24_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEV0493184.1"
                     /translation="MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPRFITNNFMVNDSSSNTPQIQTIY
                     DELEPPRQGKVLNYAKRQLKEQKNEEETKINEVSEAIRLYSYDYYDHPASAGTGQYLN
                     DVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDLVFIQTSVDLNDGVIGVFNYNGDA
                     YIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRIIGEVVDLYREK"
     gene            3959..4159
                     /locus_tag="VXC24_001058"
     CDS             3959..4159
                     /locus_tag="VXC24_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493185.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            4327..5754
                     /locus_tag="VXC24_001059"
     CDS             4327..5754
                     /locus_tag="VXC24_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0493186.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIAFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERGVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDEKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
     gene            complement(5890..6651)
                     /locus_tag="VXC24_001060"
     CDS             complement(5890..6651)
                     /locus_tag="VXC24_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0493187.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6684..7310)
                     /locus_tag="VXC24_001061"
     CDS             complement(6684..7310)
                     /locus_tag="VXC24_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0493188.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7326..7643)
                     /locus_tag="VXC24_001062"
     CDS             complement(7326..7643)
                     /locus_tag="VXC24_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0493189.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(7640..7939)
                     /locus_tag="VXC24_001063"
     CDS             complement(7640..7939)
                     /locus_tag="VXC24_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0493190.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(8189..8377)
                     /locus_tag="VXC24_001064"
     CDS             complement(8189..8377)
                     /locus_tag="VXC24_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV0493191.1"
                     /translation="MKASTWVYDKGEWYYVSSSGAMLANDWVKDNGKWYYLASSGKML
                     RNTYTPDGYYVGNSGAWQ"
     gene            complement(8628..9302)
                     /locus_tag="VXC24_001065"
     CDS             complement(8628..9302)
                     /locus_tag="VXC24_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493192.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(9308..9754)
                     /locus_tag="VXC24_001066"
     CDS             complement(9308..9754)
                     /locus_tag="VXC24_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493193.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9868..10371)
                     /locus_tag="VXC24_001067"
     CDS             complement(9868..10371)
                     /locus_tag="VXC24_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0493194.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(10368..10730)
                     /locus_tag="VXC24_001068"
     CDS             complement(10368..10730)
                     /locus_tag="VXC24_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0493195.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10796..12655)
                     /locus_tag="VXC24_001069"
                     /pseudo
     CDS             complement(10796..12655)
                     /locus_tag="VXC24_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(12694..13143)
                     /locus_tag="VXC24_001070"
     CDS             complement(12694..13143)
                     /locus_tag="VXC24_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0493196.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(13267..13983)
                     /locus_tag="VXC24_001071"
     CDS             complement(13267..13983)
                     /locus_tag="VXC24_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0493197.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14864..16279)
                     /gene="ply"
                     /locus_tag="VXC24_001072"
     CDS             complement(14864..16279)
                     /gene="ply"
                     /locus_tag="VXC24_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0493198.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(16290..16622)
                     /locus_tag="VXC24_001073"
     CDS             complement(16290..16622)
                     /locus_tag="VXC24_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493199.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16693..17301)
                     /locus_tag="VXC24_001074"
     CDS             complement(16693..17301)
                     /locus_tag="VXC24_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493200.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17314..17772)
                     /locus_tag="VXC24_001075"
     CDS             complement(17314..17772)
                     /locus_tag="VXC24_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0493201.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17897..18296
                     /locus_tag="VXC24_001076"
                     /pseudo
     CDS             17897..18296
                     /locus_tag="VXC24_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19061..19321)
                     /locus_tag="VXC24_001077"
     CDS             complement(19061..19321)
                     /locus_tag="VXC24_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493202.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(19380..19931)
                     /locus_tag="VXC24_001078"
     CDS             complement(19380..19931)
                     /locus_tag="VXC24_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493203.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(19921..20118)
                     /locus_tag="VXC24_001079"
     CDS             complement(19921..20118)
                     /locus_tag="VXC24_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493204.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(20122..20916)
                     /locus_tag="VXC24_001080"
     CDS             complement(20122..20916)
                     /locus_tag="VXC24_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493205.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(21324..21749)
                     /locus_tag="VXC24_001081"
     CDS             complement(21324..21749)
                     /locus_tag="VXC24_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493206.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(21878..22261)
                     /locus_tag="VXC24_001082"
     CDS             complement(21878..22261)
                     /locus_tag="VXC24_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493207.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(22283..22489)
                     /locus_tag="VXC24_001083"
     CDS             complement(22283..22489)
                     /locus_tag="VXC24_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493208.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(22476..22649)
                     /locus_tag="VXC24_001084"
     CDS             complement(22476..22649)
                     /locus_tag="VXC24_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493209.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(23008..23964)
                     /gene="lytA"
                     /locus_tag="VXC24_001085"
     CDS             complement(23008..23964)
                     /gene="lytA"
                     /locus_tag="VXC24_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0493210.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(24340..25710)
                     /locus_tag="VXC24_001086"
     CDS             complement(24340..25710)
                     /locus_tag="VXC24_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0493211.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         8030 a         5514 c         4531 g         7820 t
ORIGIN      
        1 ctcaagaaaa ctagtgtttc ttaaaagttt ttcaactaac tcagggtcgg cctttacaaa
       61 ggtggactct tttttcccac tatacggata ttttcttggt ctcatttttt ctcctttcct
      121 atttttcaaa gtcctaaaat tgaaatttct ctcttttatt ttttagagaa gtattagttt
      181 gttgtaagtt agtagttatt actaagttag tgccgttagg cttagattat tgtatagtta
      241 gtacttgttg tatagttagt acttattaga gggcaatttt acacatggca attttacaca
      301 tggcaatttt acacatggca attttacaca tggcaatatt ttccaactgt atttttaaac
      361 tccgttatct gtggataact ctttctcaag attagttttt agatactcaa agtaatcatc
      421 tgaaataggc atatctgaaa aaaatctata taccgttacg cctttacctc tgcctaaccc
      481 taagcgatat actctgagat agcctgcttt ctctaaaagc ttaaagtgct catctacggt
      541 gcgcctgctt attcctagac gtcgtgcaat ctcgtcagga tacacaaccc aatcagactt
      601 attcatcaag attactgtaa ggatacctat cgttgttgcc tttaaacgtt tgtcttgagc
      661 ataagcatta ttcaaagatg tgtaattccc atgagtattc ctgattatat actgcatacc
      721 tcatatttaa tcccctttct ataactctcg ctcgttcatt cacacctctc ctagattatg
      781 atttaattcg tattttttgc ctaaaaaaat aaaatccttt tcaacattgt atagtcgagc
      841 aagtttatct aaaagatcca ttggaatttt tgaactatca tgctcatact tcaacagtgt
      901 ttgttgatga atgttaagtt tatcggcaac ttcttttgca gataagttat aatttgttct
      961 tattgctctc aatgtcattt tcggcacgtt cctacctcct tatttttcta tttgttcctc
     1021 gcaattctgc tataataaag ctagaaagga ggtgatgtta tgactgatta tcaattagaa
     1081 gcttctctaa ttgtccttgg caaagaattt gatagaacca agaaaaacgg aaaagaaagt
     1141 tttagtgttc atgtttcttt ttttgatggt ttagatgcta atcagcatct tcaagagttt
     1201 gcacgacaat atcccgtaaa gattgaccgt tcgaactctg accaaataac ttttctaata
     1261 aagtaatatc gtttagaggg aagggattgg tttcaactct atcgttaaac gttaaaacaa
     1321 cttcacactt ctccagataa tgattggtaa attccactcg ctcaactccg tcgagaaaca
     1381 ttccatcgac gaatacagca gggtggtttt ttcttgccgt caacaataca tcattctctg
     1441 atgtatttac tgatatagtt ctgttagacg ccatttgttt gaccctttct ttagatagac
     1501 cgtcctagtc ttttagaaat gatttctaca tctgagtcgt ccagtttcaa ctggtcggct
     1561 ttttcattta aacgagcttc gacaacttgg ttaatttcaa tccattctcg ttttgtaaac
     1621 tggcttctga attttagaaa ttcgtttagt ttttctttca taccctcgtc ctactttcca
     1681 ttgccctgag ttcaatctcg tggctgactt gtttcaatag cttctcacac actattttag
     1741 cttctctgta cgttgtagat tcgctgatga agtagtcagc aagttcgata attttatctt
     1801 ccaattctaa ctacctttca aatgtggtat aatcaaaata aaaatgattg gagaaaaaag
     1861 ctatgaaaac cactatcgtt tcattctctg gcgcgagtcg ccagacagta aaatttgaat
     1921 atcctgaata ttgcccacat tgcggaaaga atatctcgcc tgaaatgata tacgtttcag
     1981 acagtgagga cagttactct agtggagatg ctcgctttgt tgttactttt cgttgctcac
     2041 gctcaacttg taaaaaatac tttgctgttg agtatatttt cacatctaca tctaaacctt
     2101 gtataattgc tgaatacagc taccgccctc caatcaaggt aaaactccct gaaaacatag
     2161 aaaaagtttc tcccgttttt gttgaaatct attctcaagc aacaattgca gaaagagagg
     2221 cattagacca aatagcaggt gtcggctatc gcaaagcagc cgaattcctg ataaaggact
     2281 acgcaatttc caaaaatcca tctgatgaag gaaaaatcaa atcaattatg cttgggcaag
     2341 taatttctac atacttaaac gattttccaa aaattcaagt cttggcaaaa tctgttgcct
     2401 ggataggcaa tgatgagact cattatgtcc gcagacacga tggtaaagat atcgatgatt
     2461 taaagaagtt cattctttcg gcgactcaat ttattgctgc tgattacgat gcagatgaag
     2521 cgttgatttt tacatcttct tctgattgag aaatcttaga gtcaatctca tccactttct
     2581 cagcaatata tgtcacagtc ctcaatatct cgttgagggc tgttctttct agttcgttca
     2641 tcttcccacc tccttgtctt ttttattttg ctcttggagc aacaacctgc caaggattcg
     2701 aaccttggtg ataccaatca ggctacattt aatttatcaa gcattcctgc aaatgctgca
     2761 tcaaaacgaa tgtcatcgat ttcctcttga gtgaaaccag aatcgagaag gtaacgctct
     2821 tggcgttcaa tctcctctgc taactctgtc catccaaaag cgaattgacg gcagttagta
     2881 cagaatgctt caagctggct gtaaaggaag ttttcctcgt aagtgccttg gattaaagtt
     2941 tccttagcta ctgctttaaa gatgttgatt gctttctcgt ttaatgtgtt catggtgttt
     3001 ccctccggtt tgtttttgtt atttccttaa gcttgattat attatactac gatttaaatc
     3061 gtatgtcaat gatttttcga attttttcgt aattttttcg aattttttat ttacaaaatc
     3121 gaaaataaac ggtattatat agtaaagaag ataggaggta aaaatatggc aagaggacga
     3181 gggaaattaa ctcctcaaga taaagaggat atgaaagtct tttctgcaaa tcttaactca
     3241 attttatctg atagaaattg taaacaagct gagctgtctc gagcaacagg aataccgcct
     3301 agtacattga cagggtatgt aaaaggaact tctttgccaa tccctggtaa tgttcaaaaa
     3361 attgcagatt tttttggagt tcctaaatct gtattagatc ctagatttat aactaataat
     3421 ttcatggtca atgactcttc ttctaatact ccccaaattc aaaccatcta cgacgaacta
     3481 gaaccaccta gacagggcaa agtcctgaat tatgcaaaga ggcaactgaa agagcaaaaa
     3541 aacgaagaag aaacgaagat aaacgaagta tcagaagcta ttcggctcta cagttacgac
     3601 tactacgacc acccagcttc cgcaggtaca ggccagtatt tgaatgatgt acgagtggaa
     3661 cggattgagt taccagtaga tgttgatgct gactttgtca tccccatcaa aggtgactcc
     3721 atggagcctg actaccacga tggtgacctg gtattcattc agacaagtgt agatttgaat
     3781 gacggagtta tcggagtatt caactacaac ggcgatgctt atatcaagca gcttgttatt
     3841 gatgaagacc aggcttacct acatagccta aaccctgaat ataaagatat gccaattaca
     3901 ccagacaccg acttccgaat tatcggcgaa gtcgtggatt tgtataggga gaaataacat
     3961 gagtaacgaa agtagaccga tggaagtgat taaacacaac ctagattgca aatgccacag
     4021 acgaagagag tggattagag taaatgataa atggcatgct atcgagtttt cggtagacga
     4081 tccaaacgaa cctcctatga cagaggaaga gaaagccaac gtggccttaa ttcttcaaca
     4141 acacttatcg aaagaataaa accaactgtt tccaaaatgg aaataattgc aaacaaaaaa
     4201 agcctcacgc tctcaaagtt tggcgactcc gagcgtgagg ctagtggcaa gaaaaacttt
     4261 tcaaaagata ttaccttttg agacgttttc ttgtacctat tttatcaaaa aaggggtaca
     4321 aattcaatga aaacaacgaa taaagtcgca atctacgtca gggtgtccac tacttcgcag
     4381 gtggaagagg gttactctat cgatgagcag aaagacaagc ttgaagccta ctgtaaaatc
     4441 aaagactgga aaatctacga tgtctacgtt gatggtggtt tctcaggtgc taacactcaa
     4501 agacctgaat tggagcgttt aatctcagac gtgaagcgca agaaagtcga tatagtgcta
     4561 gtctacaagc tagaccgcct cagtcgtagc cagaaagata ctctgtttct gattgaagat
     4621 gtgtttgcta aaaacgatgt ggcatttatc agcttgcaag aaaactttga cacttctacg
     4681 cctttcggca aggcttcaat cggtatgcta tcagtattcg ctcagctgga gcgtgagcag
     4741 attaaagagc gtatgatgtt aggaaaagaa ggacgggcaa agaatggaaa atccatgtca
     4801 tggacgacaa tagcattcgg ctatgattac tcaaaagaaa ctggcgtctt atcagtgaat
     4861 ccgacccaag cgctcattgt caaccgtatt ttcacggaat acttgaacgg taagccagta
     4921 gtcaagatca tcagagactt aaatgctgaa ggtcacgttg gaagaaaaag accttggggc
     4981 gaaacaatca cgaaatactt gctgaaaaat gaaacctatt tgggaaaagt aaagtacaaa
     5041 gataaggtat acgaggggca gcatgaacca attatcactc aagaattgtt tgacttagtc
     5101 cagcttgaag tcgaaagaag gcagatttca gcctatgaaa aatataacaa tccaaggccg
     5161 ttcagggcaa agtatatgct ttctggatta atgaaatgcg gatattgtgg tgcttcactt
     5221 ggtctgagat atacaagaaa agacaagaat ggaatctctc atcataaata ccaatgcagg
     5281 aaccgacaca gcaaagattt agaaaaaaga tgcgaatcag ggtggtactc taaagaggaa
     5341 cttgaaaggg gtgtaatcaa ggaacttgaa agaattaaat ttgatccaaa atataaaaat
     5401 gagacactcg ctaagaaaga agagactatc aaggtcgagg agataaagaa acaactcgaa
     5461 cggataaata atcaagtctc aaaattaaca gaattgtact tggacgaaat catcactcgg
     5521 aaagagttgg acgagaaaaa tgataaaatc aaaacagaaa ggcaattcct ggaagaacag
     5581 ctcgaaaatc aaaaatcgaa tgttctgagc atccgaaaga gaaagctaac acggctacta
     5641 aaggacttcg atgttgaaaa attaagctac gaagatgctt caaaaattgt caaaaatatc
     5701 ataaaagaaa ttattgttac aaaagacggc atgtcgataa cgctagattt ttaaagggtc
     5761 tagcgtattt ctgtatttta gtcaaagtaa ttatgataac tttattatac atattttctt
     5821 cctcctactt atctattcgt aggaaatcaa aaaaagttac agaaatttgt aacttttcga
     5881 ggaaatttct tattttttat gaatcatgaa acctgtcgcc tgttgattgg ccataatggt
     5941 catatctgta atctgaacac ggcgaggctg actggtcaca tagactactg tgtctgcaat
     6001 atcctgagct tgcaaggctt ctattccttg gtaaacggac gcagctcgct ctttatcacc
     6061 atgaaaacga acagttgaga aatctgtttc gacaatccca ggctgaatgg ttgtcacctt
     6121 gatatccgtt gcgatggtat caattcgcag tccatccgaa aaggtcttaa ccgcagcctt
     6181 ggtagctgag taaacagcgg caccagcata ggcgtagatt cctgcggttg accccatatt
     6241 gataatatga ccttgattga cttttatcat tgctggcaag aaacagcgag taaccgccat
     6301 cagaccttta acattggtat ccaacatggt caacatatcc aactcctcat agtcttgata
     6361 gggagccaag tcaagagcca gtccggcgtt gttgaccaag atatcaatcc tccctatcgt
     6421 ttctagaata tcagagcaaa cagtcttcac catgaccata tccgtcacat ctagtggaaa
     6481 agtccagacg gtttgatttg gaaagcttac tgcaaactcc gacttgagga tttctaatct
     6541 gtctatccgt cgtcctgtta gaacgacatc ctcaccctgc tccagataag cacgcgcaat
     6601 cgcttcaccg attcctgagg ttgctcctgt aatcactaca ttttttgcca tcttatttcc
     6661 ttctatcaga tgctgacaag ttcctaggca gtccagtgtt tcgctgggtc gaacggtgtt
     6721 ccgacaactt ggtcttctga taattcaagc accccacgtt tttgtggagc atttggcaga
     6781 tgcaattcac gaggactgca catcatacca aaactctttt caccacgaag ttcacctggg
     6841 aaaatgagat tcccttttgg catcatagct ccaggaagcg cgacaatggt tttcaacccc
     6901 acacgcgcat tgggagctcc tgcaacgatt tgtacagtct tatcacttgc gactgcaact
     6961 tggcagatgt tgaggtggtc actatctgga tgggctacca tctcaacaat ttcaccgaca
     7021 acaaacttag gttccttatc attaacaatt tcttctgtaa aaccttccgc ctgcaactct
     7081 tggttcaaac gagcgacttg ctcatctgtc aaaaagactt gaccgcgctc tgcaatttca
     7141 aataaacttg aaacttcgaa aatattccaa gccactgttt ccccattatc tttgagaaaa
     7201 acacgggcta ccttgccttt gcgctccaca tccagtttgg catctccgct atttttcacg
     7261 atgaccataa ggacatcacc gacatgttct ttattatatg taaaaatcat tgtttccttt
     7321 ttctcctatt tcagtcctgc taaaaagtca ttgatttgtt gcttgctttt acggtcgcga
     7381 ttgacaaaac gaccgatttc cttgtccttt tctagaacaa caaggctagg gattccatat
     7441 acatcccaga gtttggccaa atctatatac tggtctctat ccactcgaat aaaggtaaac
     7501 tctggattag tctcctcaat ttctggtaag gcaggataga tataacggca atcgccacac
     7561 cagtccgcca caaaaaggaa gaccttctta ccgtcttttt ctactaaaga tgccaattct
     7621 tctaaacttg ctggttgtat cataagactt cctcctcata gactaggtct tcattttcat
     7681 agacaaaagt ataatgacgg ccatcctcaa aaatgacgcc accaagcaag ctctctagac
     7741 tgctttcata gacttgaaca tagagggtcg caatttcccc catgtctgaa aaatggtctc
     7801 gtacaatcgc tgtcaactct tcctgagtct tcatgagctt atggtcatct gcaacttttt
     7861 tcgtagcaag ggcaaggctc ccaataccaa gcagagccag acctgccatc cacatttttt
     7921 tagctttcat accattcatt ttaacacaaa aaaggcttta ggacaaatga ggaaacagca
     7981 aaaaagcaag taaaaagcct cttcctttaa ggaaaaggac ttcttatact caatgaaaat
     8041 caaagaccaa actaggaagc tagccgcagg ctgctcaaag cactgctttg aggttgtaga
     8101 tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatgaag ctgacgtggt
     8161 ttgaagagat tttcgaagag tattattctt attgccaggc gcctgagtta ccaacgtagt
     8221 aaccatcagg tgtgtaggta ttgcgaagca tcttacctga tgaagctaga taataccact
     8281 tgccattatc tttgacccaa tcattcgcta gcatggctcc agaagaactt acataatacc
     8341 attctccctt gtcataaacc caagtgcttg ctttcatggc tcctgagcaa ttaaaggttc
     8401 aaaaaactgt ccaatatcat tcattttttt aaagcatttt acactacatc atccacgctg
     8461 taggacatag atacatcaaa cgtaagagcc aaaatatcga aaaatataca acttttaaag
     8521 gcaacatttc attttttaaa gtctaacaac catagaactg aaatcagagc aaggcatcaa
     8581 cttcctactc ttagtacgtc tattttgatg gttgaagtga agatttttta tttaacgtag
     8641 acaagctcca acttcccaaa agccacatct ccacggataa tcaaggtttt gctggttggg
     8701 gctacaggag cgtcagcctt agctgcacca aaggaggttt ctactttcaa atctacacgc
     8761 cagtgttgtg gaacatagac ggttgcattc ccgaaggcca cttcaatatt taaagttgca
     8821 aaatcaccta gcatctctgc attatcatag tagattttag catccccaaa agcgacttcc
     8881 acttggtcat ctacgagatc ttgatcttgc ttatagaagg tcccgctacc aaaagcgact
     8941 tccttatccg tgacgactgt ttttttccca ttgtaccacc attttttttc attccagaac
     9001 ttacttgaat gcgtcagata accaacacca agtaccacca agatgctagc ccaaataaga
     9061 gaatgattgg taactggtaa caagtcataa gcgtaatttg caatgatgag cgccagtaaa
     9121 cctgtaaaaa ctgccgaagt gagatgacgt ctaaggatgg actcaatgga cttataagca
     9181 aaaaaaacaa tacctagtaa aggccatatt ttaccatcca aagaaggaat tccaaaattc
     9241 ccttgcagca agatccaagc tgctaaaacc aataaaacaa taccaaatgc tttctttttc
     9301 atgtttttta cctcatgttt cttagatttt cttttaggag ggattggtaa tgccgtgaga
     9361 catgaacctc cttgtgcgtc tgataaaagg aaatggtgcc cgttcctgaa aaggacttgt
     9421 ccactgagta aatctgacgg atgtttgcga tcgttgactt ggaaactcga ttaaaatagc
     9481 gaggcaagat agactccaac tcatagagct tgaggcgaac ctcataagct tccttctggt
     9541 tatgagcgta gatcttgctc ccttctgttt caaagaagag aatttctgac aggtctagat
     9601 aatattcacc tgtccccttg taaaaagtca acctcggagc ctttgactct tgcaagagcc
     9661 gttgcaagtc tgcaatttca tctgtcaaag tgggggtctt gatgacaatt tcagtctcct
     9721 ctaaattgcc gtcaatctca attcgtaact tcatcacatc tcctttctga ctctactata
     9781 tcaaagctaa gttaggaata caagggcaaa aaagcaagtg gtcaatttga agcagtaagt
     9841 ggttgtagga ctagcttaac ttacatgtca gaataggaag aaaaggaatc cccacaccag
     9901 accacaagca tagccaacca agacatcctt gggataatga acacccccta aaaccctcac
     9961 caaccccagc aaagctgaaa agatcaagca tactaagcca ataggtagac tagcatgcag
    10021 acaggccatg gagatgatag ttgcagaaaa gacatggcga ctgggcatcg accgtcccga
    10081 actatcctta tcaagaaggg gacagatatc ccaagtttca taaggtctcg ggtgattgat
    10141 tttcttacga aacagggaca aggccacaaa acctgatgca ggaataagca cataaacccc
    10201 aacttgctga ccaagtccta gttgcaggta agtggtgact agcaagatca gatagaccag
    10261 gggcatggcg actgtcatca aacgattgaa actgcgtaat aggaataaaa gaattggacg
    10321 actagttagt ctggagctga tatttcgata ccattcttga taatttttca tttatgcttc
    10381 tcatactttt ctagaacttg ttgagatgtt ttccccttgg caagccaatc cactagcttg
    10441 tccaaacgac gtatttcctg catcagagga tcatcaattt cctcaatatg gacaccgcaa
    10501 atcttccctg taattgcaat tcgttcaggg acataatatg gtgcttgtag aaaaaaatct
    10561 ccgtaagtaa catccctatc cagacaagca agaacgtcac tcacttcata ccctgtcaac
    10621 caactggtca cttggtgaac tgactctgcc tttccaccct ttcgctcaac ttttgcaatc
    10681 aaggctaagt agacagcagc aaatttcata ttgtataatt tctgactcat acttctctct
    10741 ttctatgtgt actagtataa ataagaaaaa gaaggccgtc aagccttttt ttgatttatt
    10801 cttctgcttc atcttctgta aattgactat tgtacaagtc agcgtagaag ccaccttgcg
    10861 ccatcagttc ctcatagttg ccttgctcga tgatatttcc atctttcatg accaagatca
    10921 agtctgcatt tcggatgatt gacaagcggt gggcaatgac aaaggatgtg cgtccttcca
    10981 tcaaacggtc catggctttt tggatcaatt cctctgtccg tgtgtcaaca gaagaagtcg
    11041 cctcatccaa aatcaaaagc gatgcatcct taagaagggc acaagcaata gtcaatagtt
    11101 gtttttgtcc tacagacaag gtcacggtgt catccaagat ggtatcatag ccatctggca
    11161 aggtcataat aaagtggtga attcccacag ccttactagc ttccatcatt cgttcatcac
    11221 taatccctat ttgattatag atgagattgt ctcgaatagt tccttcaaag agccaggtat
    11281 cctgcaagac cattgaaaag gcatcatgca cttctgaacg cgtcatagcc ttggtatcca
    11341 caccatcaat gcgaatactt ctcttatcaa tctcatagaa tttcatcaaa agattgacaa
    11401 tggttgtctt accagcccca gtcggcccaa caatggcaac cctttgacca gcatgagctg
    11461 tcacagagaa gtcatagtct tgaacattga caccgtccac cagaatttct cctgctgaca
    11521 cgtcgtagaa acgtggaatc agattgacca gagttgattt accagaacct gttgacccaa
    11581 taaaggccac tgtttgacca gtttctgctt taaagctaac atgttcaata actgcctccg
    11641 aatttgccgc atagcggaag gtcacatcct taaactcgac ctgacctttg aagttttcat
    11701 cagtcagctg cacttgaaca gggttttgga tagaagaatg caaatctaaa acttgattaa
    11761 tccgcttagc agagaccata gttcggggaa gaacgatgaa gagtgctccc atgagaagga
    11821 agcccatgac aacctacatg gcataagaca tgaaaataat catgtcacta aagagaggca
    11881 gacgcgctat cggagcagcg tcgttaatca cataggcccc aatccagtaa atcgctacac
    11941 tcaaaccact tgaaatcccc atcatgatag gattcaaaat agccataaga cggttgacaa
    12001 acaaattcaa acgggtcaat tcatcattta ctgctgcaaa tttttcattt tgataatcct
    12061 ctgcattgta ggcacgaacg acacgaatac ctgttaaact ctcacgagtg atactgttca
    12121 gtttatctgt caacccctga atcaaggact gttttggaaa ggctagcgtc atcaaaacgg
    12181 tcgtcatcag gacgttgaca atcactacca caagtacggc ccagagccag tattctgaat
    12241 gacctaaaat cttcccaata gcccagatag ccataattgg accacgcgtt accacttgca
    12301 agcccatagt aatcaacatt tgaacttgag taatgtcatt ggtagtacgc gtcaagaggc
    12361 taggaattga aaatttctta atctctgtct gcgagtaatc caaaactcgg ttaaaaatat
    12421 cacttctcag cctactagta taagaagccg ccactcggga tgcaaaaaat ccaactgcaa
    12481 ctacggacaa gaaggcaaga aaggacattc ccatcatcat gcttgccggc tgccacaact
    12541 catctaaatt agtttcttga ctacctagca aatccgtaat tttcgagata taggtcggca
    12601 cttccaactc tagatagacc gaaaagcaag taaagagaat ggctagtaaa atcatccccc
    12661 attcttttct actaattctt ttggctaatt tctttattct ctcctcctat tcccttgata
    12721 ttttgcctgt agttgaccga gaaccttctc aaaaatcagt aattcatctt catcaatatc
    12781 ttccatcaac tgcttgtcta tgcgttcaaa aaaagcctta acctgttgca tctgagaacg
    12841 tgctttgtcc gtcagacgaa caaacttagc ccgcttatca acaggactcg cctccaattc
    12901 caccaaacca ttttgcacta tacgcttaac cagattacta gcaacagact tggtaatatt
    12961 gagttcctga tcgatatctt taatcaagac caagtcttgg tttttctcgc gattatccaa
    13021 aaaatgcaca acctgacctt gcggcccacc cataaattca atgccgcaac gtttggcttc
    13081 cttttgcacc atcaggtgaa tttgatgacc aaaacgctta aagactaaca tcggtttacc
    13141 cataatctcc cccttctaaa taaaaatagt tctctggaga ataattaaat ttctatgaga
    13201 actattttct tgattaaaaa aatcccaagt gattttctca cttaggatca tgttctatag
    13261 gttaaattaa aacccatcta cgttcgtata aatcttttgg acgtcttcgt cgtcttcaag
    13321 aacgctgtaa agtttttcaa aggtttcaag gtcttcgcct gacaattcca cttctgactg
    13381 aggaatcatt tccaattcag tcacttggaa ttcttcaata ccagactcac ggagggcaac
    13441 gatagccttg tgaaggtcag ttggcgctgt gtaaactgtg attgtacctt cttgtgcttc
    13501 tacgtcatcc acatccacat ccgcttcgag caattgctca aagactgcgt ccgcatcttc
    13561 acctccaaat acaataacac ctttgttgtc aaagaggtaa gaaacagaac ctgaagcgcc
    13621 catgtttccg ccgtttttac caaaggctgc acggacattg gctgctgtac ggttaacgtt
    13681 agaagtcaaa gtatccacaa ttagcataga gccatttggc ccaaaacctt cgtaacgtcc
    13741 ttctgtaaag gtttcgtctg tgtttccttt ggctttatca atcgctttat cgataatgtg
    13801 ttttggcact tgggcttgtt tagcacggtc gataacgaat ttcaaagctg agtttgattc
    13861 tggatctgga tcaccttttt tagctgctac atagatttct acaccaaatt ttgcatatac
    13921 tttagagttg gctccatctt tagccgtttt cttggctacg atattggccc atttacgtcc
    13981 cattaggaat ctcctttttt cacattttaa tctttcttat tataacacaa gtttttttga
    14041 ttttcactag aggaaatgga ttttattagc aaatcaagct aggatagcac tttacctgct
    14101 aagatggtct tgcctttcta tctttatcaa cagacactca tccacattca aaaaacaaac
    14161 tagaccatta tctgcaaata gaaagtttca gccaagtttg acaaagtcag ctcaaattac
    14221 tgtttgaagt ttgtagatat aagcgacaaa aacaatcata ctgcaccttt tgttgacagt
    14281 ctactccaga catatcatag ttcaagtaaa tactttgaaa ttcaacagtt cttataggcg
    14341 ctattgtatt ctaagaaatc aatagaagag tttctaagca aacctctaat actcaataaa
    14401 aatcaaagag caaactagaa agctagccgc aggttgctca aaacactgtt ttgaggttgc
    14461 ggatagggct gacatggttt gaagagattt tctaagagta taatttacgt gttcctaaga
    14521 tggagaagtt agactagtac actggcactt ctaaaccatt gctagcaatt gatttgttca
    14581 tatttaattt cattttttcc ataaatgggt attagatata aacagcaaaa tatttccgat
    14641 acgtgtcatt cttgaatttc caatcatcta aaacaagtaa aggataatca atcccctgta
    14701 tatcaaggaa ttggctaccc tttttacttt tttacacatc ctgtttgata gactcatttt
    14761 aacatcacga gcatactcca atggaaatcg ctaggcaaga gataaacttt cagatatccg
    14821 cagagagatc atcgcctctt tttgtcgcaa gcattctcct ctcctagtca ttttctacct
    14881 tatcctctac ctgaggatag agagttgttc cccaaataga aatcgtccgc ttacgcacta
    14941 gtggcaaatc ggttttttca taaaccgtac gccaccattc ccaggcaagc ccggtacact
    15001 ctctaatttt gacagagaga ttacgaacat tcccttttaa aggaatacta gtggtaaagt
    15061 gagccgtcaa atcctgccca tttctgtccc aagccttagg agtcaagact tccttacctt
    15121 gatgatcata ggataattca tcccaagtaa tataatattg ggcaacatag gcaccactat
    15181 gatccagcag taaatctccg tttctgtaag ctgtaacctt agtctcaaca tagtctgtac
    15241 tgttttgaaa ggtcgcaact acattgtcac gtaaaaaaga agttgtatag gaaatcggca
    15301 agcctggatg atctgctgta aagcgactgc cttcttgaat caagtcctct accatatcca
    15361 ccttgcctgt tacaactcgg gcacccgaac ttgggtcgcc ccctaaaata accgccttca
    15421 cttctgtatt gtccaaaatc tgcttccact ctgtctgagg agctaccttg actcctttta
    15481 tcaaagcttc aaaagcagcc tctacttcat cactcttact cgtggtttcc aacttgagat
    15541 agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct gcagaaattc
    15601 ctctctgttt taaatcctct accgttacag tatcttgaaa cacatctcct ggatttttaa
    15661 cagcgtctac gctgactgta taataaatct gcttaaaatt aacaatctga atctgctttt
    15721 cacctgaatg gacagagtta aaatcaatat caagagaatt ccctgtcttt tcaaagtcag
    15781 aaccaaactt gaccttgagt tgttccatgc tgtgagccgt tattttttca tactgcattc
    15841 tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac aaatcgttta
    15901 ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta tcgctacttg
    15961 ccaaaccagg caaatcaata ctataagtca tcggagcacg atcaaccgca agaagagtgg
    16021 gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag aggcgactgt
    16081 cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc ttctttcttt
    16141 cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga ttttcaatac
    16201 tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt ataaagtcat
    16261 ttactgcttt atttgccatc ttctacctcc taataagttc ctggattgag ttgcataaac
    16321 tcagacttgt tcagcgaaat cagccgtggt tggactaagt gatccaaaat ttcctcgtac
    16381 aattcttctg agacattgcg tcgccgtctg gctagataag aagtcggaat aaccgtatta
    16441 tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg attacgagct
    16501 agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag agctggtttg
    16561 aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat acagatatac
    16621 atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata aagagctaca
    16681 acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa catagacagg
    16741 attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc gcgctgtcaa
    16801 tttagtagca tcttgtctct tcaatacaaa atgcttgtcg ccaataacct tgacaatata
    16861 atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct gagaactcaa
    16921 gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag gagctaactc
    16981 ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag ctgatacttc
    17041 ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg aaactccaga
    17101 aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac ataagtcttt
    17161 catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga aaaatatctg
    17221 gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga gcaagggcga
    17281 caggtaactg gattgagaca tttcctctac ctcctactct tttttaactg gagcatctgc
    17341 actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct ctgagataag
    17401 accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat atttctccgt
    17461 ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt ggtaagaaat
    17521 ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc cgagactgga
    17581 taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac aaaagacagc
    17641 tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc tacgatgttg
    17701 aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca ggtacatttc
    17761 ttctggcgtc atattcgtaa ctcctttcat ttactttgat aaccatagta taacatattt
    17821 gaatatcaaa gtatagtaaa aactggacta taacttatta gacttcctgc gaaacaaaat
    17881 atggtatagt agttctatga atgatgaagc aagtaaacaa ctaactgatg cacgatttaa
    17941 gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat taaaaacagc
    18001 ttatcaaaaa agtcggacaa gctggtaaaa tcttggctga cagtaattat caagggctca
    18061 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccactaacag
    18121 ttgaagataa agtctataac catgcgctat ctaaggagag aagcaaggtt gagaacatct
    18181 ttgccaaagt aaaaacgttt aaaatgtttt caacaacctg tcgaaatcat cgtaaacgct
    18241 tcggattacg aatgaatttg agtgctggta ttatcaatca tgaactagga ttctagtttt
    18301 gcaggaagtc tattatatat atgcacagac atatgaaatc tttttgatac agccttcttt
    18361 ttacatagag agacagcagt tatgatatat ttatccattc acaacatctt ctgtaccaat
    18421 actacaataa ttggtacatt ttgattacac aatcgtttca aaaaatatga tggaagactg
    18481 agtattttat agtaattccc ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg
    18541 aaacacccta gcctcagcaa aggactatga tcagcatttc ctagccaata ggacgctcca
    18601 aatcacctat tctaagtcca tcactagctt ggtcagtaag atacagactg caaggcaaga
    18661 ctgacgtggt tgatgagatt ttggaagagt attacaatca tagattcacc agtagacttg
    18721 accgcagatt taactatagt agattgaaac tagaatagta cacttctgct tctaaaacat
    18781 tgttagaaat cgatttgact gtcctgatca atttgtcctg ttctcgtttc attttactat
    18841 actaaaaaac cacctgaaac aaatcaagtg actagaggat aaaaacaaag actgggcaaa
    18901 aagttttgaa aagcaaaaaa cgcataatat caggtcttga aaaaccttga tactatacgt
    18961 ttgattgtgg gaagattgac ttcattttct cctgaaattg aagttttttc tagtttccag
    19021 gtatagacga attcaatata gccatctcgc tacaattatt ttaaccatcg aaaaaatttt
    19081 tcagaatttc aaaaatttca ttttgatcca atgaaatgtc attattttga agaatagttg
    19141 acttcacagg ctctaattct atcacaaagc ggtgcatgtc tgcttttacc gcactacttg
    19201 atgttatagc cgataacttt tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat
    19261 tcaaatgctt tttaatggac ttacttaaac cttgagcacc tgtggcagag cgctccctca
    19321 tatccagcca agctttagcc ttaaaaataa ttaatactca atgaaaatca aagagcaaac
    19381 taggaagcta gttgcaggct gctcaaaaca ctgttttgag gttgtagatg gaagctgacg
    19441 tggtttgaag agattttcga agagtataga ccacaattac tcaataccga atacccctga
    19501 atggtttctt ttacatgcac caatatatta taataatctt catccaataa taaggctgat
    19561 aaactagcat cttggtcaaa atataaggga atttctcgac cgtccttctt taatggatat
    19621 tctggtaaga tactaaatag ttcaatcata gaaggaaact cagaattagt tgttgtaaat
    19681 cgaaaaagct gcgctttctc atctttctga cttccttgat actctcccaa ttctaaaaaa
    19741 tgattcaagg tagtataaaa ttccttattt tttacttcat caatgatgac catatcataa
    19801 tcttttgttg tgcgactttt aaatccttgc gaatccaata cgatagaggt agcagttccc
    19861 ccaatcagaa cataatagtt ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta
    19921 ttagctggca tcatcttctc ccagatactg taatatcata ttttctagtg cttcactctc
    19981 ttcctctata cgtgggtcat catcatcttt taaggtcaaa taaagagaaa tcggatctac
    20041 aaattgttta tcatgattat ttttaaaatc attccaaaac tcagatacaa aaggacgata
    20101 tttccatatc tctagcatct ttcattttaa aacatgctga gaaagtggca aggataactg
    20161 attgaatttt ctctgccata tgacatagct aatattttca tccgtttcag ctaaaaaagt
    20221 tgaatgcgac aaagcataag caccaccata tagaaggtta gaaacagatt ttatctgctt
    20281 tatatcgcca tctggcaata aaatccgttt tttgatggga ttaaataaac atgacacgga
    20341 ttttaagaat aattctttct ttgacaccgt atatgtgtaa agcttatttt gcttgtttaa
    20401 ccaatataaa gctttaaaag tcctcaaaca cctataaatt gttgagtttg gaagtccagt
    20461 gacttgtgaa agcaaatcaa catctactac tttttgacct tttgtcaata aaaaggcaat
    20521 ccacgttaat tgttcgctag gtgttaattc cttagggact tcagtatcat tcgcattgag
    20581 tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg gaactctagc
    20641 ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa caacatccat
    20701 attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac tcccccttct
    20761 cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat actcaaacct
    20821 ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat caacataaaa
    20881 ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt ctatcatttt
    20941 tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat aaccaaaaac
    21001 tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact gatagttcag
    21061 gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat ttcacttcta
    21121 ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc tcctgaatag
    21181 tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc acgaagatag
    21241 tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt ccagatatga
    21301 ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat atctcctgtt
    21361 gtcatatgtt ctaaagaaaa ttcttctaca tatgatttaa catctcttag gttattactt
    21421 cctaatatcc cattatgctt tttcgctaag gaaatagaag ccgcttctcc cttaccaata
    21481 atcttgttat tatcatgatt tcttgttaaa tctctatata atgcgtattc ttcagttcca
    21541 atgtctatgc tcacaatctc agctgaaccc ttagctacca actgatctat cctagatttt
    21601 aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat aacaatttta
    21661 cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatac tgaaatacaa
    21721 tctgcatcaa taaatacacg actagtcaaa cgacaactcc cccctcttca tctagcccat
    21781 atacaatatc atatctgaaa gcatctagta acagttcctc atacttccct tgcgaaattc
    21841 tgttattttc taaaagttgt tcagttgaat taatatatta tcctaatacc atttcctttt
    21901 tactttctga caaaggacga tataaacttg tatcatagcc taatcttgaa gctgtctcta
    21961 taacactaat atccatattt ttaatttctt ctgcatcaag gtatccatca ttcctcaatc
    22021 tatataacat agctttatga ctgataccat aaaactgacc caattttata atatcttcta
    22081 cttcaagatg agttctattg gcattttctc tgatttcctc aaccatccta tacagtgaag
    22141 atgggaaaat taaaaaataa gaagcaagct gatccgcttt tctttcagtt tcatctcctt
    22201 caccaatcaa gataagactg actgaactct tcttcacctc atcataataa agatgataca
    22261 gttcatgtgc taaagaaaat ctttaccttc ctaatgacat gtctgaattg actgcaatga
    22321 gactgaactg agttccttta taacagactc cgctaatatt ctttccgagt ccataaaata
    22381 ccagcgtcaa attttctatc ttttgtacca atttaaaaat atctatcggc gcttcaccat
    22441 cagctcccaa cttttttcta agatttgaag ctttattact taaatccatt cgtgatattc
    22501 ctttcacctt tttccatttt ggcaatcatg ctttgattca aagacaaata taaagacaaa
    22561 tattcagcaa tcttatcttg agtaagattt gaagatattc taagttcttt tattcttttt
    22621 ccaacatcac atacatttat cacatacatt tatcatattc atacacctct cataaaaaga
    22681 atagcacact tttgtcataa ttttttaaat aaaaaaatta tgacaaaaca aggaagcaat
    22741 ttattgatgc tgcttaaaaa tctaaaattg atgagttcct atcaaaaatc gtatcttcaa
    22801 cctcaaaaca gtacttaaag ctatccgact cggtttacat tgtcaaattt agattttatt
    22861 tgagcataac tttctagttt gctttctgat ttttgtttaa tatagtagca aacattgaag
    22921 gaaatatctc cacaagaaaa cgcatactat taagcttttt caagacctaa taatatgcgc
    22981 tgttctgatt tgaaagacat tccattatta ttttactgta atcaagccat ctggctctac
    23041 tgtgaattct ggcctgtctg ccagtgttcc gtctggtttg aggtagtacc agcctgttcc
    23101 gtccgctgac tggataaagg catttgatac catggcgcct tctttagcgt ctaagtagta
    23161 ccaagtgtcc ttgtacttga cccagcctgt cttcatggca ccttcttcgt tgaaatagta
    23221 ccacttatca gcgattttct tccagcctgt agccatttcg cctgagttgt cgaaccagta
    23281 ccagttgccg tctgtgtgct tcctccagcg gtctgcaagc atatagcctg aactgtcaaa
    23341 gtagtaccaa gtgccattga ttttctcaaa cttgtctttt ggataagagc cgtctgaatg
    23401 tacgtaccag tagccagtgt cattcttctg ccagcctgtt tcaatcgtca agccgttctc
    23461 aatatcatgc ttaaactgct cacggctaat gccccattta gcaagatatg gataagggtc
    23521 aacgtggtct gagtggttgt ttggttggtt attcgtgcaa tactcgtgcg ttttaattcc
    23581 agctaaactc cctgtatcaa gcgttttcgg caaacctgct tcatctgcta gattgcgtaa
    23641 gagttcgata taaaggcggt agtccgtcat gaactcttct ttggttgaat ggctttcaat
    23701 cagttcaacc gctgcatagg tctcagcatt ccaaccgccc ccaacgtccc aggcaccatt
    23761 atcaacaggt cctacctgca tgatgcaacc gttcccaaca atgtgcgaga aaaaacctaa
    23821 ttctgggtct ttccgccagt gataatccgc ttcattctgt acggttgaat gcggattccc
    23881 agttgagtgt gcgtgtactt gcctatatgg ttgcacgccg acttgaggca aatctgttct
    23941 taatttactc acattaattt ccatattcta ctccttatca attaaaacaa ctcatttttt
    24001 acaatccaga accagaaact cctttatttc taccttacaa agaagacaat cttagtcacg
    24061 attaggcttg tagatagaac ttcaaaacgc actattttga cactgtaaat aggactgaca
    24121 aggtctgcat tctatctaca ataacacccc agactaaaaa gcttttcaaa agtatatttt
    24181 tacagtctct atatgtcctt ttcataaata ctatacttta ttatatcata taaaagaagt
    24241 caaaagtctg ttaaactatt ttcaacacca aactaaagac gagaacacaa gttttttcga
    24301 ttttcactag aggaaatgga ttttattcag taaatccaac taggattgca ctttggttgc
    24361 caagattgcc ttgccttctt ttatcaaggg atgacggaat aatgagaagt acagttgaac
    24421 tgtcatggca acccagataa gaggttcaca aaggataaca cccttatatc ctgcccaagg
    24481 aataatcaaa accacaaaaa cgatttttcc gattagttca ataaagctag aaactagagg
    24541 aaggatcttt tgccccaagc cctgcaagca attgcgataa atcaacaaga ggctcaaaat
    24601 gggataaaag gttgaactga tttgcagata gagacttcca ttttctatca agtaaccatc
    24661 tgtcgaacta gccaagaagg aaaccaaagc tggactggca aaaaagagga aaatacaaac
    24721 aaaaactgcc caggatatac ttaaacgact gccgattcga agaccttgaa caatacggtc
    24781 aggtcgctta gctcctagat tctgagaagc aaaggtcgtc attgatgcag aaatagcggt
    24841 cataggaaga agggcaaagg tcataatgcg tcgagctgcc gtctgggcac taataatcac
    24901 tgcaccaaat gtattaacag aaaactgtaa aatcacactg ccgatagata caattgaact
    24961 catcaagccc atagccaaac cttgctccaa gagatccgcg tacaagcttt tgtcccattt
    25021 gaaatgttta aactgtggca agagttctgg cacactttta cgaatataat aaaagcagag
    25081 aaccgctgat aaaccttgcg aaataatggt agcaagtcct gcggattgaa ctcccagatg
    25141 caattgcgta ataaaataga gatccagaac cacattaacc aaggcagaga aaatcagaaa
    25201 tcccagggct gctagactgt caccaataga ccgcaacaag cctgcaaaaa gattataagc
    25261 aaagctgaca cctacacagg tcacaatcat agaaatatat tgataagatt gaggaagaat
    25321 ttctgcagga gtatctaagt attgcaagag aggatacaag ccaagaaagc ccagcaacat
    25381 aactagaatg ctcaaaagag cacctaaaat ccaggtggct gctactgctt ccttgatttt
    25441 agtgaaattc cgagccccat aataacgagc aatgacaatc cccatgccat tgccaacacc
    25501 aagtgtaaag cctacaatca ggtcaaaaat cgctgtcgtc gctcctactg cagccaagga
    25561 ttcttgacca agaaatcgtc caacaatcaa gacatcagca gtgttataga gctgttgaaa
    25621 aatatttgat agcaagattg gaaaggtgaa gcttaagagc gagggaagaa tcggaccatg
    25681 tatcaggtcc actgttcgtt ttttattcat aaagctatta tatcagcttt ccagaggagc
    25741 gacaagaaac agcaaactta tatatagcgg aatgaaataa ggacagtcaa atcgattttt
    25801 aacaatgttt tagaagtaga tgtgtactat tctagtttcg atctattata gttggttgag
    25861 tttggaatag tacgctgtag ctgctaaaac atttc
//
LOCUS       DAVLBN010000025        25764 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLBN010000025 DAVLBN010000000
VERSION     DAVLBN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.025"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            141..305
                     /locus_tag="VXC24_001087"
     CDS             141..305
                     /locus_tag="VXC24_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0493212.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            389..955
                     /gene="amaP"
                     /locus_tag="VXC24_001088"
     CDS             389..955
                     /gene="amaP"
                     /locus_tag="VXC24_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0493213.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            967..1137
                     /locus_tag="VXC24_001089"
     CDS             967..1137
                     /locus_tag="VXC24_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0493214.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1176..1784
                     /locus_tag="VXC24_001090"
     CDS             1176..1784
                     /locus_tag="VXC24_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0493215.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1815..2018
                     /locus_tag="VXC24_001091"
     CDS             1815..2018
                     /locus_tag="VXC24_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0493216.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2113..2391)
                     /locus_tag="VXC24_001092"
                     /pseudo
     CDS             complement(2113..2391)
                     /locus_tag="VXC24_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2589..2876
                     /locus_tag="VXC24_001093"
     CDS             2589..2876
                     /locus_tag="VXC24_001093"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0493217.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3154..3924)
                     /locus_tag="VXC24_001094"
     CDS             complement(3154..3924)
                     /locus_tag="VXC24_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0493218.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3939..4787)
                     /locus_tag="VXC24_001095"
     CDS             complement(3939..4787)
                     /locus_tag="VXC24_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0493219.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4784..6259)
                     /locus_tag="VXC24_001096"
     CDS             complement(4784..6259)
                     /locus_tag="VXC24_001096"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0493220.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6582..7937)
                     /locus_tag="VXC24_001097"
     CDS             complement(6582..7937)
                     /locus_tag="VXC24_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0493221.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7947..8264)
                     /locus_tag="VXC24_001098"
     CDS             complement(7947..8264)
                     /locus_tag="VXC24_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0493222.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8281..8598)
                     /locus_tag="VXC24_001099"
     CDS             complement(8281..8598)
                     /locus_tag="VXC24_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0493223.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8611..10296)
                     /locus_tag="VXC24_001100"
     CDS             complement(8611..10296)
                     /locus_tag="VXC24_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEV0493224.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10301..11197)
                     /locus_tag="VXC24_001101"
     CDS             complement(10301..11197)
                     /locus_tag="VXC24_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0493225.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11200..12462)
                     /locus_tag="VXC24_001102"
     CDS             complement(11200..12462)
                     /locus_tag="VXC24_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0493226.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            12742..13920
                     /locus_tag="VXC24_001103"
     CDS             12742..13920
                     /locus_tag="VXC24_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0493227.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(14148..14594)
                     /locus_tag="VXC24_001104"
     CDS             complement(14148..14594)
                     /locus_tag="VXC24_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493228.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            14664..15323
                     /locus_tag="VXC24_001105"
     CDS             14664..15323
                     /locus_tag="VXC24_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0493229.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(15375..16526)
                     /locus_tag="VXC24_001106"
     CDS             complement(15375..16526)
                     /locus_tag="VXC24_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0493230.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(16541..17272)
                     /locus_tag="VXC24_001107"
     CDS             complement(16541..17272)
                     /locus_tag="VXC24_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493231.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            17501..17602
                     /locus_tag="VXC24_001108"
                     /pseudo
     CDS             17501..17602
                     /locus_tag="VXC24_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(17574..18350)
                     /locus_tag="VXC24_001109"
     CDS             complement(17574..18350)
                     /locus_tag="VXC24_001109"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0493232.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(18343..19566)
                     /gene="trpB"
                     /locus_tag="VXC24_001110"
     CDS             complement(18343..19566)
                     /gene="trpB"
                     /locus_tag="VXC24_001110"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0493233.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(19544..20143)
                     /locus_tag="VXC24_001111"
     CDS             complement(19544..20143)
                     /locus_tag="VXC24_001111"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0493234.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(20130..20897)
                     /gene="trpC"
                     /locus_tag="VXC24_001112"
     CDS             complement(20130..20897)
                     /gene="trpC"
                     /locus_tag="VXC24_001112"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0493235.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(20894..21898)
                     /gene="trpD"
                     /locus_tag="VXC24_001113"
     CDS             complement(20894..21898)
                     /gene="trpD"
                     /locus_tag="VXC24_001113"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0493236.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(21909..22475)
                     /locus_tag="VXC24_001114"
     CDS             complement(21909..22475)
                     /locus_tag="VXC24_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0493237.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(22472..23833)
                     /gene="trpE"
                     /locus_tag="VXC24_001115"
     CDS             complement(22472..23833)
                     /gene="trpE"
                     /locus_tag="VXC24_001115"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0493238.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(24754..25755)
                     /locus_tag="VXC24_001116"
     CDS             complement(24754..25755)
                     /locus_tag="VXC24_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0493239.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         8096 a         5491 c         4131 g         8046 t
ORIGIN      
        1 aaagttatat aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga
       61 gggtaggcag tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa
      121 atcactaaaa aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg
      181 catatgcagg acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc
      241 tcccatctat tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa
      301 agtaaacttt tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag
      361 tttaaatgtt aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat
      421 tttctgtatt ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag
      481 tgatctaggt attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc
      541 tagatatgtc ttttggggga cagtggttct atcaacttta gttttattat ccattttagt
      601 tgtgatgttt tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt
      661 aaaattaaag aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt
      721 gatcaagaac ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga
      781 aggtaaaatt cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat
      841 aactaatgga ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt
      901 aaaaaattac caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag
      961 taaaaaatgg aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta
     1021 tttctggctt gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta
     1081 ggagcactgg gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa
     1141 aataaaaatt actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaaca
     1201 ctaacgtaga aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt
     1261 acgaagataa agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt
     1321 tgggaatcga tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg
     1381 taacaagtgg tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta
     1441 ttgttgagta ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt
     1501 cagaagttgc taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca
     1561 tcaaaactaa agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg
     1621 ttgctgaatc aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg
     1681 gatctggttt ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg
     1741 cagcaaatgg tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa
     1801 caggagaaat tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag
     1861 aaggtgttgg gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag
     1921 ttgtttctaa agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag
     1981 aaggtgttaa aaacatgttg agtggcgacg ataaataagg ttaaaagtta ctttatcttt
     2041 ttggtaacat tagtcaagat gattctcaga aaacaaaaag ctagagattc ccaattgcgg
     2101 aaccctagct ttttaatttt gcctctttct cttattatat ttcagcaggt tgttggccat
     2161 gagtacgaat cccatgtcaa ttctcacttg acgcttccct ctcagatgac atctcttata
     2221 acccaaacaa acctttatct gcccaaagac agatttcata tcaatcttac gtttagcgaa
     2281 aatttgtcta cccttggaag ataaaagtgc ctgatattct ttagttttta aacactggta
     2341 acgttcattc atatacagtc ccttttgagg ggctgattca ggttcataat cgcagtcaac
     2401 attgatttca aggctgtttg ctttctatct cccctttttc atgatatatt ttcgtacagg
     2461 tgcttcaata gtttctatag taaaatgaac caaaaatagt acacgttgcg gtataatgtt
     2521 cttgtggcat attcattaga ttttcgtaaa aagttctctc ctatttgtga gcgaacaggt
     2581 atagtcaatt gattgtcagt ttgaagacca agagtcgtaa ggcaaaggat atggcagaat
     2641 ccatccaagg gtggctggca caatttctag tgaacctctt taaatctatt acgtttgact
     2701 gtggaaaaga gttttcaaaa tggaaagata tttccaatca tcacgatagt gagagctttt
     2761 ttgcgaatct aggatgtcca agacagcggt gtctcaacga acattcaaat agacttttaa
     2821 ggtgtcatga cttgccaaag cagacagatt tcaacgaagt cagtcaagaa ttttaggctg
     2881 ggtaaaaact caatttcagg agaaaatgaa ataaatattc ccacaataaa atgcatagta
     2941 tcaaagtttt tccaacacct gatattatgc attttttaat tttaaagact ttttcccagc
     3001 ctcaagaaat cacatcccac ctaaatcctt tggataccaa atacctcatc aggtattttc
     3061 tgagttggta agactgtcta gcttaatttg acaaatggag ggcgttaaat ccagttttta
     3121 caggaagtct atttaaatat tttcacactg accttacaaa atatgaaaca aattatataa
     3181 agtcattccc atgacaaaga ataacatccc tttaaaacag tatcttaccc aattttcagg
     3241 taagactttt gatacaaccg tccccaatac ccctccgcat atagaagcaa gaaaaataac
     3301 tggaacaggt gctaaatgat actgatttaa acctgtaacc acaacaattg tagccaaatg
     3361 agacagctgg gaaaagaaaa taattgcaag agaatacatc gttgcttctt ttatcgaaat
     3421 agaaaaaaac accatcaata aagatacatt gagcggacca ccaccaatcc ctaaaaaact
     3481 agaaattaag cccaatagaa gaccacaaat catatagaat cctatcttat caaattgata
     3541 agttttttta aaatctgtta aaacaaatga tacaagtagc atcacaaata gtaaaatcat
     3601 ttgaacaatg gatactagcc gtactgataa ttgagataac aaaacttgaa aaataagatg
     3661 acctagaaat cctcctaaaa cagaagaaaa ggataccgta aaaatcaatc tccattttat
     3721 ctctttactt tgtgaaaatc ttttgattgt tgaaataatc gccattataa aaacagagaa
     3781 actagaataa aaagcaatat cactgaccga atggtatcca aaactatcca taagtggctt
     3841 aattataatt ccaccaccca tgcctgatat agaacccaat ccactagcta ttataatgat
     3901 tagaaaataa ataatctcaa ccacttttta agtccatcct attctttcaa acatctaaaa
     3961 cctagatggc tactagtgga agtagaaata catccatttc tagcagctac tcggtatcga
     4021 ttacaataag aacaatgaca taaaaaggaa cctcctctga tagcatactc ctcatcttgt
     4081 atcccatatt ttggcaactc atagtcatct tcattaaaac tagctaataa ggtatatctc
     4141 ggattgcgac accattccca aacattccca atcatttgat atagaccaaa atcattaggt
     4201 aaaaattcat agacaggagc cgttcctata aatccatcta aggcagtatt ttcataagga
     4261 aatcttcctt gccaagtatt ggcatgataa tatccacctt ctaaaagagt atctccccaa
     4321 ggatattcag attgtcttcc tcctctagca gcatattccc actgtgcttc agtcggtaaa
     4381 gacattccgc tccaattaca gaaagccaat gcatcttcta aagcaacatg aactactgga
     4441 tggtcttcta aacccactag attactattc tcaccgtagg gatgtttcca gcaagcgttc
     4501 ggaacttgta accaccacgg agccccagca ggatgaggat atccctccct ttctgcctct
     4561 ggaacgaaca atataaaaac aaaagaccac tcttgtcgct cagctagtgt tttatagcct
     4621 gtttctttca caaattgagc aaattcttga ttcgtaactg gagtatccgc aatggaaaaa
     4681 tcctttacac taacagcgac ttgaggacct tcaaaatcat ctaaaaagcc ctcttcagaa
     4741 tttgttccca tcataaatgt cccacccttg atttttttca ttttcatgat tgactatccc
     4801 ccgttttcgt tagagttggc gttattttag aaagttcaac aggaactaac tcttcatcca
     4861 caacaaaacc ttcttctcta tatctaagaa agtctactaa ttttttcttc atctgacgaa
     4921 caataggttg atatttttca cttggataca aatcattcat ttcatgcgga tcttttttca
     4981 tatcaaataa ctgataatga tttaaaacag gaaaccagat aaatttccac tggtctgtca
     5041 aaatatattg actagaatct tttcctaaag catgttcacc atgaaattct gttcgccacc
     5101 cctcgtactg tccaaataat aaattcttaa cactccgtcc atctagttca tctgtagtag
     5161 ttcctcctgc caaatccacg agtgaaggaa aaatatcttg aattttcact aattgcttga
     5221 ttgttcccct attaccagct atcaatccag ccggatcgta aataaacgaa ggaatgtgga
     5281 tacttccctg ataaggatat ccctttctaa acagataatg ttcaccaagc tgatctccat
     5341 gatccgaaac aaaccagata atcgtatctt tatcatgacg aaattctttt agggcagtca
     5401 aaaagcgact aatttgatgg tctatatgag taatcaatcc aaaataagca gcaaccattc
     5461 ttctttgatc atcttccttt aatttccctc ttaaagcata aatagacgga atttgctttt
     5521 ctaatacttc ccaattcccg atatgcaaat cgagaaattg aggcaagcgt tccatataca
     5581 tatcaaaata gtattttggg ggatttaatg gagcatgtgg tttttcaaaa gacattttga
     5641 gaaaaaaagg aaccgttgga tctcttcttt gtaaaaatga aatggactca ctcacaaccc
     5701 agtttgttgg atgtaacttc tcatctttat cccaaggtct agcttcccaa gaattacaat
     5761 ccattccgtc atcaatcaaa tcaacatcat aaccaacttt accctttaaa aaggctagat
     5821 agtcactagc ataatcaaat tgacttccat aagccttatc atactttcta tcaacatgta
     5881 gatacccatc gtgaagtaag acatgatcaa acccaagtct ctgtctggaa ggaaaaacat
     5941 gcatcttacc aatacactct gtttgataac ccatatcttt aaagactttt ggaagagtat
     6001 tagtaaaatt ccaaggcacc tcatcttgat aaccaactcg tccactttta tcttggtcta
     6061 agccagtcaa taaagctgcc ctagcaggaa cgcaagaagg aactggagaa taggcatttt
     6121 caaaattata acctacacta gccatcatat ctaatgttgg agtgctaact agcttatcct
     6181 tactattcaa ggataaggcg tctgctctca tttgatctac aacaatcaaa ataatatttg
     6241 gctgttttgt ctgaaccata aaatctcctt tctaatatgg caaaagaggc acaagaagat
     6301 atctaccttt actgcacccc tttctatatc aatctctcta tataaaacaa taacattctt
     6361 gttatgtttt atagaaaaat gaactaaaat atgactaaat cgattaggaa attcaaatca
     6421 ttttctagta ctgttttaga agttacagtg tactattcca acttcaataa actataaacc
     6481 tttgtctaat aacaatttta gtggagataa gaaatcctac acctaactca tcttacacgt
     6541 aatctatttc tattttatca caaaaaacgc aagtaagacc attaactcaa ttcagtttta
     6601 tctgccattt tcacaaatgg gaaataagtc aagacactaa taatcaaaca aacaactgat
     6661 aagatgatgg cacgccaatc aaatgctgta gagaagaaac catataaaat tggaggcatt
     6721 acccaagtaa cgttttgtgt aacaggtgaa acaagacccc agcttgttgc ccagtaagct
     6781 accgttgcca tgaaaaccgg gctaagtaca aatggtataa atagcaaagg attcaagaca
     6841 actggtaaac cataattgac cggctcacca atattaaaca gaactggtgc tagaccaagt
     6901 ttagcaactt ttcgataatg actgtttctt gaaaaaatta aaatagcaag tactaatcct
     6961 aatcctccaa accagacaaa cgccccaaaa gacccacttg tccatatata aggaatcggt
     7021 tcaccttttt ggaaagcatc cagattcgct aacatagcaa ctccaaacag cccttccatg
     7081 atgggagcca atacatttcc tccatggaga ccaaaaaacc agaataactt attcaaaaag
     7141 atcatcagaa taactgcaaa gaaactttga gacaaaccta gtaatggcgt ttgtaacacc
     7201 ttgtaaaccc aatcaatcaa taagtcattg ctaagtaaat ggaaaacata agtcaagatg
     7261 gctactatat acatcgccat aaatcctgga atgatagaag tgaacggctt agcaatcgca
     7321 gggggaactg aatctggtaa cttgattacc cagttctttt tcattacttt acagaaaata
     7381 atagaggcta aaaatccaat catcatggct gtaaagtagc ctctggcatt aatatggttt
     7441 cctggaatca cattcccaat agttaccatc agatttttac catcaaatgc tagattatca
     7501 attccttgta agatttgatc taatttcaca tctcctacat ttgccaaagg gaaactcttt
     7561 gtaactgtac ttccaatcga aatgacaaac gaagcaagtg ataccaaacc agcagaaact
     7621 gtatcaacct tgtaaatctt agcgatattc actcccaagc aatagatgaa caacaaggaa
     7681 acaattggta tacttccctt gaataccaaa ttattgatgt caacaagcca ctgaaaggtt
     7741 ttcgtaatac tttctaggtg aaattgttgt ggtaaatcca ctagaaaagc atttaataac
     7801 aaagcaatgg aacctgtcat aataacaggc atagtcccca caaatgaatc acgtaaagca
     7861 actaaaaact tctgattccc aactttcatt gcaattggag aaagtttttc ttgcatttta
     7921 tccaacattg tattcatacc aaactcctaa tttttttcaa atcgttcgta tacttctacc
     7981 acttctttcg ccaagtcaac aaaagtcaga ctcgtcatta aatgatcttg cgcgtgtacc
     8041 atcaagaggc taattgatgt tttttccccc tgtgcctctc ttgtcaacat ttctgtttga
     8101 gccttatgcg cctgtaataa ggcagcattc gcatcagcta atcttcgatt ggctttagag
     8161 aaatcccctt tttttgctgc ctgaatagcc tccatagcat tacttttggc ttccccacca
     8221 tacataatta gccccattac agattctaaa ttactttcat ccataacatt ctcctcaatc
     8281 ttagtctaat aaactttcag ctaaatctaa aactttagaa ccattcatca ttccgtaatc
     8341 tgtcatcgga ataaccgcca caggaatctg tctatctttt agtttttctt gaaagtcccc
     8401 tagtaaatag cgaacttgag gacctaaaag caacacattt acttcttttg ttgctacaat
     8461 ttcttctgct tcaggagctg gaactgcaaa aatttctgca tccaacccct tatcttctgc
     8521 tgccttttgc atctttgtca ctagcagact tgtactcata cctgctgcac atgctaacat
     8581 aattgttact ttagccatag cttactcctt ttattttatt gtcaatgtta ctgtttttcg
     8641 atcaacttta gactcataat ctaaatgttt gggacgacta gtataatgca aattataaac
     8701 tcctggaggc atttgtgaaa tcttttcttt ttcagtttta ttgcgaatta ataaatctac
     8761 cgaagtattc cctccaaagt tattaaacat aggttcattt tcaatagaat aatctaactc
     8821 atatccacta ttagttgtaa ttccttttaa taaatcagga acatctcctc tgtttattac
     8881 tatatcctta gcgccattta ttttgggaga ttgactataa tactcttcag cttgatgttg
     8941 ttgtaaatca tttctagagt aagaaacata atcaactaca aattcagtcc ctgataaatt
     9001 attgtccact accccaggcc aacttcctcc catcgctaaa tttaactgaa catactgagg
     9061 tctattaaaa atctttttcg ctatattatc tgatccataa tatacttttc taacaatatg
     9121 attgtcaacc atccatacaa tataatcttt ataccaatca attgaaaaag tatgatacga
     9181 atcattaaag tttccactcg ataatttaaa ggctgtacca cgtcctgcaa attttccatc
     9241 atcattatcc gactgtccat aatgaagcgt ttgataaact gtcttattcc cacttccatt
     9301 tgaatttcgt tcaccaacta attccattat atctatctca cctgttgacg gccatcctcg
     9361 tccctgaaca ggattaatct tcccatcaag tgtaaaatcc gatccaagag tccagaaagc
     9421 aggaaaaact ccttgacctt tcggtaattt tgcacgcatc tctaatttac cataaagaaa
     9481 ttctactttc ccatgtgttc taacacttcc tgaattatat acaacctttc tgtgattgtt
     9541 tcttgggtta aaatactgat cttccttaga gcgattcgta gctctaagaa ctaaatttcc
     9601 cgaacgtaga aaaacattct catcacttct tacataatgt tgctgttccc aaccacgaat
     9661 tgatcctaat tcatatcccc aatatttttt atttaattgt tcgccatcaa aatcatctct
     9721 ccaaattttc ttatatgaat ttcctttaga cagttgatac atctctacat tatcaataaa
     9781 aatattagat ttttttgtag tatcgtcttc tgaccatttc actaattgaa tcaaaacttt
     9841 atcgtgttta ccggaattga aagaaaacat gtattttttc cattcggttg tattaactgt
     9901 ttgatcaaca gcttctccaa tgttattttg aacaatctct ccttgcttat tattatcaaa
     9961 ccatcttgcg gtaaaatatc cctctgctcc actaatatct actttggcaa aagcagatac
    10021 taaataatct tcattaggtt ctatatcaat aacttgtcca atatatccat ctgctctatt
    10081 atcattaatt gcagtagaag gaatcatacc tgagtaatgt ccgttactat aactctcatt
    10141 tgaattaatt attcccctat ttctagagtt ccaaaacagc tctccttgct caaaatttga
    10201 attttttatt aaattttcat tagcaaaaac tttcgcgtga ataaatatta ataaaaataa
    10261 tataaataaa cttaaaatta atttcttatt cttcatttta tcacctattt actgacctag
    10321 ccaagcgaga tactgtatgt ctcactcctc taattgcctt gctcaatgca taaatattat
    10381 cgactgttgc cagtccccca tatcctgcgt cacctatatg ttgaatatca actccacaaa
    10441 ttttatttct aagtgcaatt tccttgatag tatctgtatc agatgtttct tggctagtac
    10501 caatagcact caatacaaga ccacccttac tatgaacgag atcaacgact tcacgcaact
    10561 cttggtcatg aaaggctgga acggttccaa ctgctggaac aagtatcaca tccgcacctg
    10621 cttccaacaa ttgctctgcg acagaaagct ctgccacagg ctcattcact cctgccccgt
    10681 gcattttacc agctataatc aaacctgaga aattctcttt agcagattga actgctttga
    10741 taatctcttg attgctaact cctgttccag gatttccagt caaacagaca aagtcaaaac
    10801 ctaactcctc tattcgattc aatgtttcaa cactagcaac acgacctgca acaatttcct
    10861 gtgtttcctc tagcatcttt gcagatgggt caatcggttc caaatttaca ccaattggac
    10921 aagcaacaag ctggtgtaag cgatgaataa catcatcacc tgaactatcc aaagcataaa
    10981 ttttaggctc aaaaacatca acacaattca ataaaatcat atcagctcca aaagctctag
    11041 caatttcaga attagttata tccccaacaa atgtctcacg agtaactaca ttttcagata
    11101 gaacaactct accttcactt gctaaaatac tttgttttaa ttcttcagca ttcatctgta
    11161 atatctcaga tggatttgca ctaattaaac gtttcattct caatcctcca ataacttaaa
    11221 ccgtttttca atagctatta caaatggtaa ataaagtaag acatccaaaa caatcaatac
    11281 aatttgtaat aatgaaccag aaatacttcc tgtagcaagt aaaccactta taacaggtgg
    11341 catagtccaa cctggatctg tataagttag cggaaccaaa cctgatgcca ttgctcccca
    11401 cgctactagt aagttaaaca ttggagctaa gataaatgga actagtaaca aaatgttcaa
    11461 aacaatagga acgccaaaca ttgctggttc atttatatta aataatccag gtataacagt
    11521 tataggtgcc aaagttttta gttgtttact agctttcttc ttatgtgcta aatatcctaa
    11581 cgcaagaact aaacctatgg ttgcaccacc gccacctatg aatacaaaat tatccataaa
    11641 tacgctagta aaaatatttg gaagagtttc tccagtttga taagctactt tatttgcatc
    11701 tagattagct aaccataacg gtttcataac tgcattaaca acatttcctc cgtgtaatcc
    11761 tacaaaccaa aaactactat taaggaaaat taagataaga agaccaataa cattatttcc
    11821 taaaagtcca agtggacctc ccaaagctac ttgagcaatt tcatgaagat taggtaaact
    11881 taatttatct aaagttgcat aaacaatcaa ccaaccaaca atagtcactg caccaggaat
    11941 aatggcacta aagcttttag atactgctgg tggaacacca tccggcattt ttatctgtat
    12001 attatgattt ataaaccatt ggtagatata gccattaatc aatcctaaaa tcatagcaac
    12061 aaataaacct tttgatgcca tgaaagcggt aggcattcct gctccagcct ctcctctaat
    12121 gaaaggcgta actgtaataa aagatgataa tgacacaata ccagcaggaa taccatcaac
    12181 tttgtattgt ctagccataa agtaagcgat accaaaacta gctacaagac caagtaatcc
    12241 aaaactacta tcaacaccct tccataaata gtcagcaaca ccaatatcac ccagatattt
    12301 ttcccatcct ggaataggaa aacttgcaat aaccattagt aatgaaccta tcaacaataa
    12361 aggtatagtt agagtaatac cgtctcgaat agaaaccaac gctttattat tacccaatct
    12421 agccgctact ggaagtaact tttcttgtaa taatttttcc ataacctttt cctcttaaat
    12481 atattttatt atcaaaagtt atcaattatc tttatttttt gacgtcaagt tgttatttga
    12541 ttatcttttg ttatttatat tttacaacta taagaaagcc ttgtcaagga tttgtgtaaa
    12601 catttgatta ttttttatta tcaatatata ataaaaagag accagtaagt aatgaaaagc
    12661 ttaaaaaaat taacatctac atttatccat agcaaaaaat cataggattt taagaatctg
    12721 acaactagga agaaaactaa tatgacctta tctaagaaac aattacaact aagagctaaa
    12781 atactggaaa cagtttacac attaggtccc atttcacgaa ttgaaatcgc tactaaaaca
    12841 ggaataacac ctgcaacaac tagcagtatc acaaatgatc tgattaaaga aaatattctc
    12901 ttagaacttg gtgaagacga acacgataca agcgtaggga gaaaaaaaat cctgctagac
    12961 attcaagcta aacgatttta ctacattggt tgtgaactat ctgaaaaaca tttcactttt
    13021 gctttaggag ataatctagg aaatatctta aaggaagaga aagaaattgt tactaaacag
    13081 ttaatccaag aaaagggaaa tcaactcatt aaccagacac taaagcaatt cttaaataac
    13141 tgctctgatt atgaaataga agcaattgga atcgcgctac ctggtcgcta tttagataat
    13201 tataaaataa caacaaacaa tcctttatgg caacatatcg acttagaaat gattcaatcc
    13261 cactttgata agcctttgtt tttctctaac aatgttaact gtatggctat aggtaaacgc
    13321 ctatttagtc gccaacagaa tgaccctaat tttgcttatt ttcattttgc tagaggtatg
    13381 cactgttctt atatctacga cggaaacatt tatgggaaag gaaatctaat gattggagaa
    13441 atagggcata cagttgtttc atctgaggga gaagaatgta gctgcgggcg caagggatgc
    13501 ttacaaactt ttgctggaga atcttggtta atcaaaaaat caaaaattct atatcatcaa
    13561 tctccctatt ctctacttcc tagtttagtc aaaaatgccg atgatattga tatccaagtt
    13621 attttaactg cttatcaatt aggtgacact ggaataatca cacttatcca tcaagcctta
    13681 ctctatctta gtcaaaccat tttaaatatc agtatgatga ttgactctca aaaaatctac
    13741 ctacatagtc ctttactaac aaatcaacac atcatccaaa aactatatag tgaaatgaac
    13801 tacaaaccca aactgctcta taatcgccta cctgaagtca ttattgaacc ttacaatgat
    13861 tttacagccg cacactcagc tattgcactt tgtttgtatc atacaattct acattcttaa
    13921 ttttctatta catttaataa ataggctaaa aagagggagt atatcataaa aagcgaataa
    13981 acctgttttc tgaaaatcag aattctgttt tgttcgcttt ctttatattt ggaattatac
    14041 tcctatctcc cctttttcat aatgtatagt aaaatgaaat aataacagga cgaatcgatc
    14101 gggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    14161 aatctactat atttttgtac aggtgcttca accatttgaa cgatttcaaa tccttctttt
    14221 tggtaaagat tctgagctct ttgatttgcc tcgaagacat ttagagaaat actatctata
    14281 tcttcatttt caaaggccaa actaacaaat ttccttaaag cctggctacc taagtcttgc
    14341 tcctgtttct gggggttgat aaaaaatctc ccgatatgaa gattgctgtc ttctagcctg
    14401 attttctgga taagtcccac aaactcttgt tcatcaaaga ttgaaaagac tccttccaag
    14461 gcttgaaggg tcagtagaaa aggaatcctt ggtcccatcc attgttcttg aaaggatttg
    14521 cctagggagt tggaccactg gcatacaaat tgagcgtttt ctatactcac cttttcttca
    14581 aaacgaattg tcatcttttc ctcaccatct tatctatgtt tctccattat actatttctc
    14641 ccatttttta cgaatagata agtatgattg atttttattt ttttctcgtc gggagcattc
    14701 tcgcttcctt tcttggtttg gtcattgacc gttttccaga gcaatccatt atcagttcag
    14761 ccagtcactg cgattcctgt cagactcgct tgcgtccctt agatttgatt ccgattctct
    14821 cacaggtctt caatcgcttt cgctgtcgct actgcaaagt tcgctatcct gtctggtatg
    14881 ccctctttga attagtctta ggactcctct ttctgcttta ctcttgggaa ttgctttcct
    14941 tggggcaagt cgtcctaatc accgctggtt tgaccttggg tatctacgac tttcaccatc
    15001 aggaatatcc cttactggtc tggatgactt tccacctaat cctaatagct tcctctggct
    15061 ggaatctggt catggtctcc ttccttgctc ttggaatttt ggctcatttt atcgatatcc
    15121 gcatgggcgc aggggatttc ctctttttag cttcttgtgc tctcgtcttt agcgtaacgg
    15181 agttactgat cttgattcag tttgcttctg cgacgggtat cctggccttt ctcctgcaaa
    15241 agaaaaagga gagacttcct ttcgtgcctt tcctcttact tgctgcttgt gggattattt
    15301 ttggtaagct actgcttgtc tgataaaatc caatttctgc catatgtcct tcatgaaatt
    15361 atttcacagt taaattataa attatttctt ttgtacaaag ggatgatgtt atcaaatcga
    15421 tctgttcttc tatcttcttg atactgatca aaaaatttca tttcgactga aaatatttcg
    15481 cttataaact gtaaacgaat actttgttta gacattatag tcgctagact gactagatga
    15541 ttactcaaaa cgacgtccag aatactcttt actttgcttg gttttttaac aaaaatttga
    15601 tcatccaaag gttcaatcat tttgtaacct ttttgcgcaa tttgacgata aaagtaagaa
    15661 tgttgctttg gagtcaataa tcctaactta aaagctcgat actctaaagc ctgtatcgaa
    15721 acattcaaat ccgacttcaa taaaatataa ctatcaggat tgctgacacg cttgccaacc
    15781 ctctcttcaa atttgactaa aaactcttct tttggcaata aaaaacatga tgcaaaataa
    15841 tttgcttctt gctccaaacg attgccatct tcattcatat ctttatattt atgtaaaaga
    15901 atatgtccta gctcatgagc taagtcaaaa tttcgacgta cagatgattt attcgttccc
    15961 aacacaatat aaggtcttcc caattttgac catgcgctat aagcatcagc ttggccatta
    16021 attaatcgtt ccacgatata gatacctgaa cgttctaatt tataaagcaa atcatgatta
    16081 tcttttgaaa tacctaattt ttccctggca taaagagcca attcctcaat ggattctccc
    16141 ttatgataag attcactcac tacattactt aggtcatgaa ttataatatt aggtataatt
    16201 acaaaacttt caaaataatc aatcaaacta tctaccttat gtaaatacat agtttgaata
    16261 tctattgttt tccgtgttgc taggtctgca tttctaaagg caattacaga agaatcaaat
    16321 cgaatgctct cttcttcctg ttcaaaataa gttaaatcaa catgaaattg gttggccaaa
    16381 tgcattttgg ttgataattt aggtttcgtt tcgttggact caaactgcca aatggcttgt
    16441 tccgttaaat taattctctg agctaattct gctctactta aaccatttaa cagccgtaat
    16501 tctttcaata cccgaccatt aaacatttat atactcctta ctacttttga ccttcttgtt
    16561 tttctattct tggaataatt tcaaaatctt ctgtttccga taattctgaa aaattaggaa
    16621 tatcttgata tttagcttct tcgaaatggt acgaacttga ttgaatatac tcagacaaat
    16681 cttgaatcaa gtgtagctga ccagttcgtg catcaggcat aacaacatct acagatataa
    16741 tattgttttc tgagtccgcc tcataagtta aaatcataaa tttttcgata ttcgaatttt
    16801 tagtagcttg ttcaatttct tgaatcattt catcagaaac taactccatc tgaattggaa
    16861 aggaatgact atcttcatca tttttgtagg aagaatgttg attaagataa agtgtattca
    16921 tctgagcgta ttcaaataag tagccactct tatttttttg taccaaagga aattggttcg
    16981 taagtcgctt cttacccttt ataattaaca atactttccc atatttttct gtatttgttt
    17041 caaattctaa atatccccaa gtctgtcctg ctaattgtaa tttatactca aacaaatctg
    17101 ctgatgcaaa tgcagtatca atatgattag gtcgcgtcca tgcataacca ttcgacacta
    17161 tcattgtctc tcttttttct agacgttcat ctacataatc tttttgccct ttcatcaaag
    17221 tatctacaat tttttgtgcc tcaagcgaat caaagagatc ctgattcaac ataattcttc
    17281 ctcctccaaa tactttttaa tgaattatat cattttctta aagaaattac tacaataatt
    17341 atctttttct taaagttctg tgtcagagta atttagaaaa ttatatcttc tatagtaaaa
    17401 tcaattaaaa actgaacaaa tttattggga aattcaaatc gctttctgaa aatattttag
    17461 gaaccgtagt gtaatattcc agattcaatt cactataaaa ctgacctttc tcctgcaaaa
    17521 gaaaaaggaa agacttcctt tcgtgccttt cctcttactt gctacttgtt tgattatttt
    17581 tggtaagcta ctgcttgtct gataaaatcc tgaatcggct ctccttggtg gagagctttt
    17641 actatttttg aaccgacgat aacaccatct gacaccgcat tgaagcgttc cagatcggct
    17701 tgactagata caccaaaacc tgtcaagact gggatgtcgg ccacttgatg aagttgcgcc
    17761 aagtgcttgt ccaaatctgc acggtaattg cctgatttcc ctgtcacccc attgatggca
    17821 acggcataga cgaatccctc cgcgccttca atcaactctt tctggcgctc aattcctgtg
    17881 gtcaagctta ctaaaggaat caaggcgata tctgtatctg ccaaaaatgg ttctacaaag
    17941 ttggcatgtt catgaggcaa gtctgggata atcaagccct tcacagctgt atcagccaga
    18001 tctttgacaa agttctccac accgtactga aagagggggt tgaagtaggt catgatgacc
    18061 agtggaatct ctgtttcaat ggttttcaag gtttcaacta aagcctgggt agaggtcccg
    18121 tgggctaaac tgcgcaagcc agcttcttcg ataacaggtc catctgcaac agggtctgaa
    18181 aagggaatac ccacttcaat tgcagagaca cccaaatctt ctagaaagtg gattgtttct
    18241 cctagtccat ccaaaccttt ctcgtggtct ccagccatga tatagggaac aaaaattcct
    18301 tttccagctg ctttaatagc atttaatttt tttgttagtg tcttaggcat gagcttctcc
    18361 cttctttgct gcatctgctt ccaagcggtc tttgacttga accacatcct tgtccccacg
    18421 acctgatagg cagacaatca tagacttttc tggtccaagt tctttggcca atttcaccgc
    18481 aaaggcgata gcatggctag attccaaagc tgggataatc ccttccacac gagacaagag
    18541 ttggaatcct tccaaagctt cttcgtctgt cacagggaca tagctggcac gtttaatatc
    18601 gtggtagtga gaatgctctg gaccgatacc aggatagtcc aaacctgctg agatagagaa
    18661 ggcttcaaga atttgaccat gggcatcttg gagcacatcc atgagggaac cgtgaaggac
    18721 acctggacaa cccttggtca aggtagctgc gtggtgctcc gtatccacac caagtccagc
    18781 cgcttcagct ccatacatgg ctactgactc atcttctaca aagggatgga agagaccgat
    18841 ggcattcgac ccaccaccaa cacaggctac tagggcatct ggcagatttt gtcctgtcaa
    18901 gtcacggtac tgttgtttag cctctcgacc aatgacactt tggaagtcac gaacaatttc
    18961 tggaaatgga tgaggcccca aggcagaacc aagaatatag tgggtatcat cgatattagc
    19021 cacccatgaa cgaagggctg cattaaccgc atccttgagc acgcgcgaac catctgtcac
    19081 ggcctcgacc ttagctccca aaagctccat tcggaagaca ttgagggctt ggcgtttgac
    19141 atcttcctca cccatgtaga tggtacattc catgttaaag agggccgcag cagttgcagt
    19201 tgccacaccg tgctgaccag cacccgtttc tgcgataatt ttctttttac ccatgcgttt
    19261 ggcaagccaa acttgtccta aggcattgtt aatcttgtgg gctcctgtat ggttaaggtc
    19321 ttcccgtttg agataaatct tggctccgcc gatatgctgg gtcaagtttt ttgcgtaata
    19381 aagaggagtt tcacgtccta cgtactggcg caaaagctgg tttaattcct cttggaaact
    19441 tgggtctgcc tgactttcac ggtaggcctt ctccaactcc aaaactgctg tcatcaatgt
    19501 ttctgggaca aaacgtccgc cgaattttcc gtaaaatcca tctttatttg gttcctgata
    19561 tgccatgctt taccctctct ataaatcttc taatcttttc atgatctttt tgtccatctg
    19621 tctccactcc gctcgataca tctactgcat agggagtaaa atattgaatt gcttttacta
    19681 cattatcttc attaaggcca cctgcgataa agaagggctg tgctagtcca gtcgtatcca
    19741 gttgacccca atcaaagggc tggccacttc ctgccacagg ggcatcaaag agtagataat
    19801 ctgcctgaga attagggaca tgcccatttc catctacctg cacagcctga atactggcac
    19861 aaggcaaatt ctcaaataaa tcatctgcca cctgaccgtg aacttgaacc aagtccaagc
    19921 caactttgtc aatcgcttcc agcagttcta cccgacttgg tgaaacaaat actccaacct
    19981 ttttcacatc tgcaggaata agctttgcca actcagctgc ctcttctaaa gtcacctgtc
    20041 ttttactagg tgcaaagaca aaaccgatat agtcggctcc tgctgaaacg gctgtttcca
    20101 ccgcttcttt ggtcgatagt ccacaaattt taacctttgt caatctgcaa ctccttgatt
    20161 ctctgggcca cattttctgc ctgcataaga gctgtcccta ccaaaattcc gttaaagtat
    20221 ggggctagtc gttccgcatc ctgccctgtg aaaatggcag attcagaaat gtaatagcga
    20281 ccttcctcaa agtaaggggc taaatctaca ctggtctgca agtcgacctc aaaggtagtc
    20341 aagttgcggt tgttgacccc gataatctca gcaccaagtc tgtgggctac ctctagttca
    20401 gctagattgt gagtctccac taagacttcc agaccaagct ctgtcgcgta gtcatacagt
    20461 tccttgaggc gttcttcgga caaggctgcc acaataagca agataactgt cgcacctgca
    20521 ttgcgagcgc ggatgatttg cttttcatct atgataaagt ctttgttgag cgtcggaatc
    20581 tctacctgac tggaaatttc ccgtagataa tccaaatgcc ctttaaagaa aacctcatct
    20641 gtcaacaccg aaatcatcac tgctccgttt tcttcataag tctgggcctg ttgcacaata
    20701 tccacatcga gattgatatc tcccaaacta gggctagctt tcttgacctc agcgattacc
    20761 tgcaagcagt cctgatgatt cttcaaaaat tctgccaagc gataggtctg gcgcagaggc
    20821 tggatttgct ccagcttcat ctgctccacc tcacgcgcct tctgctctaa gattcgtgct
    20881 aaaaattcct gactcatttt tggtactcct gtaacagtct gagtttttca agggccttgc
    20941 ctctagcaat cacttgacgg gccaaggcaa ctccttcctt gatgctatca atcttaccat
    21001 tagcatagaa accaagacca gcattcaaga ctgtcgtttc caagaatgga cttgcttcgt
    21061 ttttcagaac gctaagcaaa atttctgcat tttcctgagc attccctcca cgaatatctt
    21121 ccatagcata gccttccatt cccaaatcct ctggagtaaa gcttgacaag ctgatttcgc
    21181 cattttcaag aagtgcaatc ttggttgttc cgttcaagcc agcttcatcc aacccttctg
    21241 gtccagcaac cacgatggca cgtttgcgac ccatattttt caaaacctga gctgtacttt
    21301 ctaggagttc tggacgacta attccaagaa gctgtgtttc taaagccatt ggatgaatca
    21361 gtggaccagt caagttcata atcgttggaa ttcccaattc caaacgagct ggcatgatgt
    21421 atttcatagc tgggtgcata tttttagcga agagaaagac gatgccagtt ttatcaaaga
    21481 ccttacctag ttcagctggt ttgaggtcaa gattgattcc caaggcttcg aggacatctg
    21541 cggaaccaga tttagaagaa atcgagcggt taccatgctt ggccatgtga ataccgccac
    21601 cagccaagac aaaggctgca gttgtggaaa tattaaaact gaaagacttg tccccacctg
    21661 taccacaatt gtccatggca tcatgaatct cagttggaat atgctgggca tgtcctctca
    21721 tgacttgggc aatggctgtg cgttcttcag gtgtttcccc cttcatctta agagctaaga
    21781 ggagagaagc aatctgcgct tcagttacac gcccagttat gatacgctca atgacatccg
    21841 tcatttccac acctgataaa ttttcaaatt ttgctagttt ttcaataatc tctttcatcc
    21901 tagtttcctc actttacaac ctcctcgata aaattccgaa tagaagacaa gccgtctggc
    21961 gttccaatgc tctctggatg gtactggaag ccataaatcg gtaggttttt atgttgaatc
    22021 cccatgatgg tttggtcatc agtcgaacga gctgtcactt caaagtcttc tggcatttcc
    22081 tcaatcaaaa tactgtgata acgcatgacc gcacgtccat cctcaatacc ttgatacaaa
    22141 acagatggcg cttcaaagtt gatattgctc tgtttcccat gcatgacttt tggagccaaa
    22201 cctagcttac caccaaagac ttctgcaatg gcttggtggc ccaaacaaat ccctagaatc
    22261 ggcttcttgc ctgcaaaatc acgaatcatg tcttccatct ttccagcatc aactggccaa
    22321 ccaggaccag gagaaaagac cagaccatct gctttttcag cttcttcata cagcttggaa
    22381 tcatcatttc tcagaacctg aacttctgca aaattcccaa tgtattgggc caagttatag
    22441 gtaaaagaat catagttgtc aatcaataaa atcatggtct tagttctcca attctagtca
    22501 tagattttgc tttgttaatg gtttcttggt attcgttttg ggcgatagag tcgtagacaa
    22561 tccctgcccc agcctgcaca taggctcttt gatttttgag aatcatggtt cggatggcga
    22621 tggccaaatc catatcaccc gtcgcagaca agtagccgat tgccccagcg tatactcccc
    22681 gtttttccgt ttccagttca tagatacgtc tcatcgctcg aatctttggc gctccagaaa
    22741 cggttccagc aggaagcgtt gctttcaagg catccatggc agtgagttct gcaagcaaac
    22801 gtcccttgac cacactggtc aaatgcatga cgtagcggaa gagctccacc tccatatact
    22861 tagtaacttg gacactggcc gtttcagaga tgcggccaat atcgttacgc cccaagtcta
    22921 ccaacattcg atgttctgct gtttccttct catcagagag gaggtcagtc gccaaggcct
    22981 tgtcttcttc atccgtagcc cctcttggtc gcgtccctgc aatcggattg gttgtcacga
    23041 tgccattttt gacagaaacc aaactttctg gactagctcc gatgatttga taatccccaa
    23101 aatcatagaa ataaaggtaa ttagaaggat tagttacgcg gagatttctg tagaagtcaa
    23161 atggatttcc agtaacttct gctgagaaac gctggctgag tacacattgg aacatatcac
    23221 cattacgaat caagtcacga gctgtttcca ccatttcctc aaacttctga ggagcgatat
    23281 gcggtttgaa gtctaacgga gatagatcca agtcttcaaa ctcatttgga gcaggaatgc
    23341 gtaattcctc aagcacttgg ttcaaggctt tttccaattc ttcttgacta cgctcactat
    23401 agagagcatc ctcgatgaca tgtatcttct ccttcttgtg gtcaaagacc atatagctct
    23461 catagacaaa gaaatgcatg tctggcgtcc caattgtatc ctcagggatt tgaccaattt
    23521 cttcataaag cgaaatcata tcgtaaccca caaaaccaat ggctccacca ccaaaaggga
    23581 gctctgagtg gtgctgactc ttatgaatca cttcataaag gaaatccaag ggatcccgat
    23641 caatcacttg accattttga tagagaactc cattttcaaa cttaatctca aaaactggat
    23701 tataggctag gatagaaaaa cgagccgttt ccttgtctct cggaatactc tctaaaataa
    23761 ccttatgttg cccctttaag cgcatataag ccaagattgg tgataagaca tctccatgaa
    23821 tgattcgttc cattgtaatt tccctttcag ttctaattct agttcgtggc gactgtatga
    23881 aaaatcccca cgcaaaataa cttgcgtgag gacgaaattc gcggtgccac ctcaattata
    23941 ggatttctcc tatctctcat tcctgtctca gatacctcct gtaacaggct gtgcgataaa
    24001 gggcactccc ttgagaatga tgttttcttc tctcgtttca gatgaaccca actttacagc
    24061 tttctctgct tgttttcagc aaccacaagc tctctgtgag agaaaagact gtaatttttc
    24121 catctattat tttttagctt ctagtaatct gcaatcgcag ctaggtcctt gcctccacga
    24181 ccagagacat tgatgaagag atgttcatct cggtacacct ttatactctt cgaaaatctc
    24241 ttcaaaccgc gtcaacgtcg ccttatcgta ggtaacgacg gatagaaaaa agcccacaca
    24301 cagaatatac ttccgtgtga gggcgttggt aacgcggtgc cacctcaatt ataaagggac
    24361 tatcccttta catctctgcc ttgtttaaca acaagctgca ctgtaaggtg tgcgcaccga
    24421 attttcattg tttcaaattc attttcaaaa tcagcccact ttcactactt ccaaccacct
    24481 attcacaatc accacaggct ccctgaagat caaaaatagt tacttttctg atttgttgaa
    24541 cttattttaa tactttgttt tttctttgtc aagacttttt tacgattttt ttgatatcat
    24601 tcgaatgtga ccatatcttc cttagatcga acatgaacat gtcccacttg ttagaaattg
    24661 gatccaactc aatagaaact gaatggaggc taaacagaac ttattttaga acactccatc
    24721 ttttccacta ggattttcaa gaattaaaca atactagaaa ctctgtctcc taacaaattt
    24781 aggagaaact tcaacagatg tgacactttc ccctttaata attgctaaaa caccttctat
    24841 catttcttta gccaatttaa cataattggg agcaattgta gacaaagctg gagtataata
    24901 ctgagaaata ggaatattat caaatccaat gatagaaata tcatctggaa taagaattcc
    24961 tttctcatag cacgcacgaa tcaagccctg aaccttttca tctcctgaaa caaaaataat
    25021 gtccggataa ttttgggtag tcaagtgctg cattgcataa gaataaactg aatcaattgt
    25081 agataagcca taaatgactt ttaaatccat aaagtaattt ttatcattca gaaaagaacg
    25141 cacacctctt tcacgatcct tattaacatg agattctcct cccataagca accacatatt
    25201 tttaaatttt tcttcagtta cagctttcat catatcataa gtagcttgaa aattattatt
    25261 agatacatag actactccag acgtttgaga ttcaccgaaa acaagaaaag gcatatggtt
    25321 cttctttaaa tactgaattc tgatatcatc tacactttca taaaaaacaa taacaccatc
    25381 tactaggcta cctgtgcttg atataattga attactaatt gtatcctcct ctccaaagta
    25441 ctcaactata gcattaacac caaattcttt acacgtccgt aacactttat ctaacagcgt
    25501 atgaaaccaa attaaaggaa aagagtcgat tttttttaca gaaatcaata tatttatagc
    25561 ttctttttta gttaaatttt ttgcatacgc atttggaata tacgacaatt cctctataac
    25621 tttttgaatc gcttgataag tttcttcttt aacatttact ccaccattaa taactcgtga
    25681 aactgttttt ggagaaaaac ctgataaacg tgcaatatca taaatagtta cctttttccc
    25741 atttatattt ttcatttcag tcct
//
LOCUS       DAVLBN010000026        25545 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLBN010000026 DAVLBN010000000
VERSION     DAVLBN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.026"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            39..862
                     /locus_tag="VXC24_001117"
                     /pseudo
     CDS             39..862
                     /locus_tag="VXC24_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            884..1623
                     /locus_tag="VXC24_001118"
                     /pseudo
     CDS             884..1623
                     /locus_tag="VXC24_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            1636..2802
                     /locus_tag="VXC24_001119"
     CDS             1636..2802
                     /locus_tag="VXC24_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0493240.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            3310..4803
                     /locus_tag="VXC24_001120"
     CDS             3310..4803
                     /locus_tag="VXC24_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0493241.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            4816..5937
                     /locus_tag="VXC24_001121"
     CDS             4816..5937
                     /locus_tag="VXC24_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0493242.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            5997..6233
                     /locus_tag="VXC24_001122"
     CDS             5997..6233
                     /locus_tag="VXC24_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0493243.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            6230..6643
                     /locus_tag="VXC24_001123"
     CDS             6230..6643
                     /locus_tag="VXC24_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0493244.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            6761..7726
                     /locus_tag="VXC24_001124"
     CDS             6761..7726
                     /locus_tag="VXC24_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0493245.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            7750..8276
                     /locus_tag="VXC24_001125"
                     /pseudo
     CDS             7750..8276
                     /locus_tag="VXC24_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466610.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            8306..11656
                     /locus_tag="VXC24_001126"
     CDS             8306..11656
                     /locus_tag="VXC24_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0493246.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            11927..12004
                     /locus_tag="VXC24_001127"
                     /pseudo
     CDS             11927..12004
                     /locus_tag="VXC24_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12242..12712)
                     /locus_tag="VXC24_001128"
     CDS             complement(12242..12712)
                     /locus_tag="VXC24_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0493247.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(12729..15002)
                     /locus_tag="VXC24_001129"
     CDS             complement(12729..15002)
                     /locus_tag="VXC24_001129"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0493248.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            15349..18450
                     /locus_tag="VXC24_001130"
     CDS             15349..18450
                     /locus_tag="VXC24_001130"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0493249.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            18532..19539
                     /gene="pfkA"
                     /locus_tag="VXC24_001131"
     CDS             18532..19539
                     /gene="pfkA"
                     /locus_tag="VXC24_001131"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0493250.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            19598..21103
                     /gene="pyk"
                     /locus_tag="VXC24_001132"
     CDS             19598..21103
                     /gene="pyk"
                     /locus_tag="VXC24_001132"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0493251.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(21837..22062)
                     /locus_tag="VXC24_001133"
                     /pseudo
     CDS             complement(21837..22062)
                     /locus_tag="VXC24_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            22910..23782
                     /locus_tag="VXC24_001134"
     CDS             22910..23782
                     /locus_tag="VXC24_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0493252.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            23795..23959
                     /locus_tag="VXC24_001135"
     CDS             23795..23959
                     /locus_tag="VXC24_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493253.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(23928..24272)
                     /locus_tag="VXC24_001136"
                     /pseudo
     CDS             complement(23928..24272)
                     /locus_tag="VXC24_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            24415..24726
                     /locus_tag="VXC24_001137"
     CDS             24415..24726
                     /locus_tag="VXC24_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493254.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            24730..25446
                     /locus_tag="VXC24_001138"
     CDS             24730..25446
                     /locus_tag="VXC24_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0493255.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         8119 a         4322 c         5365 g         7739 t
ORIGIN      
        1 aatgatataa aattttgaat atagagagtt ttctggcaat gaatcaatcc tacttttatc
       61 taaaaatgaa agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta
      121 ttcttcttcc taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc
      181 atgacgggca aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta
      241 tcccagctat caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg
      301 atggtatggg gcggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag
      361 agcagcagtt tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc
      421 cttttatcga tgagacctat cgtacaaaag cagactgcca gcatacggct atgattggtt
      481 cctcactagg aggcaatata cccagtttat cggtttggaa taccaagacc aaattggttg
      541 cttgggcgtt ttttcatctg caaactggct ccaccaagaa gcctttaacc gctatatcga
      601 gtgccagaaa ctatcgcctg accagcgcat cttcatctat gtaggaacag aagaagcaga
      661 tgatacagac aagaccttga tggatggcaa tatcaaacaa gcctatatcg actcgtcgct
      721 ttgctattac catgatttga tagcaggggg agtacatctg gataatcttg tgctaaaagt
      781 tcagtctggt gccatccata gtgaaatccc ttggtcagaa aatctaccag attgtctgag
      841 attttttgca gaaaaatggt aagttaagaa aggaaaaaac gaaatgcata ttgaacatct
      901 tagccactgg agtggtcatc ttaaccgtga aatgtacctt aaccgttatg gacatggtgg
      961 gattccagtt gtggtctttg cttcatcagg tggtagtcac aacgaatact atgattttgg
     1021 catgattgat gcctgtgctt cctttatcga ggaaggcctt gtccagttct ttaccctatc
     1081 tagtttggat agtgagagct ggttggttac ttggaaaaat gctcatgacc aagcggaaat
     1141 gcaccgtgcc tacgaatgtt atgtgattga ggaggccatt cttttatcaa gcacaagaca
     1201 ggttggtttg atggcatgat gacgacaggt tgctctatgg gagcctatca tgcactcaat
     1261 ttcttcctcc agcatccaga tgtctttacc aaagtgattg ctctcagtgg tgtttacgac
     1321 gcacgtttct ttgtcggtga ttactacaac gatgatgcta tttaccaaaa ctcgccagta
     1381 gattatattt ggaaccaaaa cgacggctgg tttattgacc gttaccgtca ggcagagatt
     1441 gtgctgtgta cggggcttgg agcctgggaa caagatggtt tgccatcctt ttacaagctc
     1501 aaagaagcct ttgacaagaa acaaattcca gcctggtttg ctgaatgggg acatgatgtc
     1561 gcccatgact gggaatggtg gcgtaaacaa atgccttatt tcctcggtaa tctctattta
     1621 taaaaggagt tacctatgaa ttaccttgtt atttctccct actatccaca aaactttcaa
     1681 cagtttacca tcgaactagc taataaaggc atcacagtct tgggaattgg tcaagagtct
     1741 tacgagcaat tggatgagcc cttgcgcaat agcttgaccg agtattttcg tgttgataat
     1801 cttgagaaca tagatgaagt caaacgtgca gttgcttttc tcttttataa acatggtcca
     1861 attgaccgca tcgagtctca caatgaatac tggcttgagc tagacgcaac actcagagaa
     1921 caattcaatg tttttggtgc caaaccagag gatctcaaaa agacgaaata taagtctgaa
     1981 atgaagaaac ttttcaaaaa agcaggtgtt cctgtggtac ctggagctgt tatcaagacg
     2041 gaagcagatg ttgatcaagc agtgaaagaa atcggtcttc caatgattgc caaacctgat
     2101 aatggagtgg gagcagccac aacctttaaa cttgagacag aagacgatat caatcacttc
     2161 aagcaagaat gggaccattc aaccctttat ttctttgaaa aatttgtcac ttccagcgaa
     2221 atctgtacct ttgacgggct cgtggacaag gatggaaaga ttgtcttctc aacaaccttt
     2281 gactacgcct atacaccgct tgacctcatg atttataaga tggacaattc ttattatgtg
     2341 ctcaaggata tggatcctaa actgcgcaag tatggggaag caattgtcaa agaatttggt
     2401 atgaaagaac ggtttttcca tattgagttc ttccgtgagg gggacgatta tattaccatc
     2461 gagtacaata accgccctgc aggtggtttt accattgatg tttataactt tgctcattcc
     2521 ttggacctct atcgtggcta tgcagctatt gtcgcaggag aggagttccc ggcgtcagac
     2581 tttgaaactc agtattgttt ggctacttct cgccgtgcaa atgctcacta tgtttattca
     2641 gaagaggatt tgcttgccaa atatagccag cagttcaaag ttaaaaaagt catgccagct
     2701 gccttcgcgg aacttcaagg agattacctg tatatgctga ccactccgag tcgacaagaa
     2761 atggagcaga tgattgcaga tttcggacaa cgtcaagaat aagaactatc ggattaagga
     2821 aattaactcc cttaatcctt ttgttttgtc tgataaaaaa taagagcatc ccaacaaggt
     2881 agctatcata aaacttgttc gataactatt tgaagcagga ttaggtggtc agaaattgaa
     2941 ttttaatatt tcaattgagt catagtattg tgtttgcgta tccttaaatc agctaaaagg
     3001 atccatgacg acacctatac gatatagttt tcaagatacc aaacaagtct attaatactc
     3061 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt ttctcaaaac actgttttga
     3121 ggttgtggat agaactgaca gagtcagtat catataccta cggcaaggtg aagctgacgt
     3181 ggtttgaaga gattttcgaa gagtataaaa tattcaggtg acgcatagat atagttaatt
     3241 gaagctttgt ttgaaatctg ataaaataat gatattacta agttttaaaa actaaagaaa
     3301 agggaagata tgattacagg cgaattaaaa aataaaatcg atcagctgtg ggaaattctt
     3361 tggacagaag gaaacgcaaa tcctttaaca aatattgaac agttgactta tctcttattt
     3421 atgaaagatt tggatagtgt cgagcttgga cgtgaaagtg atgctgaatt tctagggatt
     3481 ccttatgagg gagtttttcc aaaagataaa cctgaatacc gttggtcaac ttttaaaaat
     3541 ataggagatg ctcaggaagt ttatcgttta atgactcagg agatttttcc gtttattaaa
     3601 aatctcaagg gggatacaga tgatacagcc ttttcacgat atatgcgaga agctattttt
     3661 caaataaata aacctgctac gcttcaaaag gcaatttcta tcttagatgt ttttccaact
     3721 aggggattag atgtagattt tgataatgac aaacaaagta ttactgatat cggagatatc
     3781 tatgaatatc tgttatcaaa attgtcgacc gcaggtaaaa atggacagtt ccgtacacct
     3841 cgtcacatca tcgatatgat ggttgagttg atgcaaccga ctatcaaaga tatcatctca
     3901 gatcccgcta tgggttctgc tggcttctta gtatctgcta gccgttactt aaagcgtaag
     3961 aaagatgaat gggaaaccaa tacagataat atcaatcatt ttcataatca gatgtttcat
     4021 ggaaatgata cggatacgac tatgttgaga cttggggcga tgaacatgat gctacatgga
     4081 gtagaaaatc cacaaatcag ttaccttgac tcgctgtctc aagataatga agaagccgat
     4141 aaatatactt tggttttagc aaatcctcct tttaagggct cacttgacta caattcaacc
     4201 tctaatgacc ttcttgcaac cgtaaaaacc aaaaaaacag aattactctt tctttctctt
     4261 ttcttgcgaa ctttaaaacc aggtggacga gcagcagtta tcgtacctga tggtgtcctt
     4321 tttggttcgt ctaaagctca taaaggaatt cgtcaggaaa ttgtagagaa tcataagctt
     4381 gatgctgtaa tctcaatgcc tagtggtgtg ttcaagcctt atgctggagt ttcaactgct
     4441 attctcatct ttacaaaaac tggtaatggt ggtactgaca aagtctggtt ttacgatatg
     4501 aaagcggatg gtttaagttt ggatgataag cgacaaccga ttagcgacaa tgatattcca
     4561 gatattatcg aacgctttca tcatcttgaa aaagaagcag aacgtcagag aacggatcaa
     4621 tctttctttg ttccagttgc tgagataaag gaaaatgatt atgatttgtc tatcaataaa
     4681 tataaagaga ttgagtatga aaaagttgag tatgaaccaa cagaggtcat cttaaagaaa
     4741 atcaatgatt tagaaaaaga aattcaagct ggcttggctg aattagaaaa attactcaag
     4801 tagggaggtg gctgtatgaa aaaagtgaag ttgggggaag tcttatctct aaaaaaagga
     4861 aagaaagcca ctgtacttgc tgaacaaaca actctaagcc aacgttatat tcaaatagat
     4921 gatttaagaa ataataataa tttaaaattc actgaaagtt taaatatgac tgaagcactc
     4981 ccagatgata ttctaatagc atgggatggt gctaatgcag gaacagttgg ctatgggtta
     5041 tcgggagctg ttggtagtac aattacggtc ttaaaaaaga atgagcgata caaagaaaaa
     5101 attatatcag attacttggg agtctttttg gaaagtaaat cgcagtattt acgagatcat
     5161 tcaacaggtg caactattcc tcatttaaac aagaatatat tacttgattt acaattagaa
     5221 ttgctaggta tcgaagaaca agagaacatt atctgtattc ttaatacgat taaaaggctt
     5281 attactaaaa gaaaatttca gttagatgaa ctaaacttgc tcgtcaaatc ccgatttaac
     5341 gagatgtttg gggaaaataa aatatttgaa agcattgata acttatttga tattatagat
     5401 ggtgataggg gcaaaaatta tcctaaatca gatgagttgt ttagtgagga gtactgttta
     5461 tttttaaata caaagaatgt tactaaaaac ggattttcat tcgatacaaa gcaatttatc
     5521 actaaaacaa aggataaatt acttcgaaaa ggcaaacttg agcgttatga tatagtcttg
     5581 acaacaagag gtactgttgg aaatgtagcg tactacgatg aattaataaa atataaacat
     5641 ttacgtataa attcaggtat ggtaatatta cgtcccaaga caccaaatct aaatcagaaa
     5701 tttattatcc atgttttaag gaataataat tatagtcgag tgatatcagg aagtgctcag
     5761 cctcagttac caattacaaa attaaaaaaa atacttctcc ccctcccccc actagccctc
     5821 caaaatgagt tcgcagactt tgtagtccag gtcgacaaat cacaattggc aatccaaaaa
     5881 tctctggaag aacttgaaac tttgaagaaa tctctgatgc aggagtattt tggctgatat
     5941 tctgccattg taattacggt aatgatttgt tataatactt caaaggagga aatcagatgg
     6001 tagtaaaaac aagaaaacaa ggaaattcaa tcaccattac gattccaagt gaatttaata
     6061 ttccaagtgg tgttaaatac gaagcgaaat tgttaccaag tggtgagatt atctttactc
     6121 ctgaagaatt ggggcagcag gtttcttatg tatctgatga tgcctttgac ttaaatttag
     6181 ataaaatatt tgacgaatac gacgatgttt tcaaagcttt ggtggaaaaa tgacaatcta
     6241 tctgacagaa aagcaaattg aaaaaataaa tgctttagca attcaacggt attctccaaa
     6301 tgagaaaatt caaacagtta gttcttctgc cttaaatatg attgtgaact taccagaaca
     6361 atttgtcttt gggaagtctc tttatccaac aatttttgat aaagcaacga tactatttgt
     6421 ccaattgata aagaagcatg tttttgctaa tgctaataaa agaactgctt tcttcgtttt
     6481 ggtcaaattt ttacaattaa acggctatcg tttttctgta acggtagaag aagcagtaaa
     6541 aatgtgtgta accatcgcag tagaagcttt aactgatgaa aaaatgacaa gctactccaa
     6601 atgggtttct gaacattctg ttagagaaaa ggtcaaaaag taacctagta tgctggattt
     6661 gaatgagcac aagaaaataa atgaacagac aatattagaa ttctgtaatg cagaaactga
     6721 tattgtctct ttttattgat gaataagaaa gtgagaaatt atggaatcaa aagttacaat
     6781 tatcatgcaa gaaatgttac ctcttttaaa taatgaacaa ttactagcgt tgagagagag
     6841 tttagaacat catctagtag acggaaaaaa gcagcagaag tattcgaata ataacctgtt
     6901 gcaactattt attaccgcca agcaggtaga gggctgtagc tcaaaaacaa ttcgttatta
     6961 ccagaggacg attgaaaact tgtttaatgc tattaaagag tctgtgacac aactcacaac
     7021 agatgattta aggagttatt tagcaaatta ccagtctgaa aaggattgta gtaaggcaaa
     7081 tttagacaat attaggcgta tattgtcttc tttttttgct tggcttgagc aagaggaata
     7141 tatcattaaa aatcccattc gacggataaa gaaaattaag actgagcaaa atgtgaagga
     7201 aacttatact gatgaacatt tggaaattat gcgtgataac tgtgaaaatt tgagagattt
     7261 ggcaataata gacctactag catcgacagg tatgcgtgta ggggagcttg tacagttgaa
     7321 tcgttcagat attgattttg aaaacagaga gtgtgttgtc tttggtaaag gaaagaagga
     7381 gagaccagta tattttgacg ctcggacgaa aattcattta agaaattatc ttaacgacag
     7441 aaaagatagt caccctgctc tttttgtaac gctagttgga aaagcccaga gacttggaat
     7501 tgctggtgta gagattcgct taagaaagtt aggagacaaa ctcggcatac aaaaggttca
     7561 cccacataag ttcagaagaa ctttagcgac taaggcaatt gataaaggta tgcctatcga
     7621 acaagtccaa aaactgctag gtcatagcaa gattgacaca accttggcct atgccatggt
     7681 caatcaaaat aatgtcaagc attcacacca aaaattcatc tcttaaaagc aaattcccga
     7741 tttaacgaga tgtttgggga tcctttaaat aataacaaga aatttgcagt aaaaacggga
     7801 caacagtgtt ttaaattttc aagtggaaaa tttcttgata aacatgatag agtttttgaa
     7861 ggttatcctg cctatggtgg aaatggcatt gcttggaaaa gtcgaaaata tttaattgat
     7921 aatcctacta tcatcattgg tcgtgtaggt gcatattgtg gtaatgtaag aactacccac
     7981 ggtaaggtat ggataagtga caatgctata tatataaaag aatttaagaa ttccgatttc
     8041 aatcttgtat ttttattaga attaatgaaa gtaattgatt ttagtaaatt tgctgatttc
     8101 tcaggtcaac caaagataac tcaaaaacca ttagaaaatc agaaatatat cctcccccct
     8161 ctagccctcc aaaatgagtt cgcagacttt gtagccctgg tcgacaaatc acaatttgct
     8221 tgtgagatag ctatataaaa gtgtggagaa atagcttgaa atttagtata atatagctaa
     8281 actatttgtt taaagtgaga aaaaaatggg aaattttagc tttcttttaa aaaatgacga
     8341 atatgaatct ttttcaaaac cttgcattga agctgagaat atgattgcta catcaactgt
     8401 ggctactgcc tttatggcgc gtcgtgcttt agagcaggct gtccattgga tatatagtca
     8461 cgattcatat ttagaagctc cctatcgtgc tactctatct tctttagtat gggatgatga
     8521 ttttagggat atcgtagatt ctgaactcca caagcagata gttctgttga ttcggtgggg
     8581 aaaccatgct gctcatggtg gtgaaattaa ggaacgagaa gcgattttag ctttgcatca
     8641 tttgtatcag tttgttaatt ttatcgatta ttgttacagc aatgagtttg tggagcgtta
     8701 ttttgatgag aagtgcttac cactttcagc aaacatcaaa taccgagaaa ctccacaatc
     8761 tatgataaag ttacaagaca gtttaccaga actgcctgat tttcatgaac agatggctgc
     8821 tcagtccgta gaagttcaag agacttatac tgaaaaacgt gagactgcag cgcaacggca
     8881 agatgtgcct ttccatattg atcaattatc tgaggcagag acaagaaagc tctttattga
     8941 tatcgatctc cgtttagcag gatggatatt tggagaaaac tgttgtgttg agatagccgt
     9001 tgatggtctc aagcacggtt caggaattgg ttactgtgac tatgtacttt atggtaaaaa
     9061 tgggaaaatt ttagcgattg tggaggctaa aaaagcctct gtcaatccag aagtagggga
     9121 agtacaggtc aaagaatatg ctgaagcttt ggagaaacat atcggctatc agccaatttg
     9181 ctttattaca aatgggttga agcactatat acttgatggt ccgaaccgac gccagattgc
     9241 aggcttttac tctcaagaag aattgcaatt agtgatggat agacgtcatc ttcaaaaacc
     9301 acttgaggat atttctagta aaattaggga cgatatttcc gggcgtcact accaaaaaca
     9361 tgccattgca agcgtttgtg aagctttctc taatcatcgt agacaggcac ttttggttat
     9421 ggcaactggg gcggggaaaa ctcgtacagc agtttctcta gttgatatct tatcacgtca
     9481 taactgggta aaaaacgttc tcttcttagc cgatagaact tccttggtta agcaagccta
     9541 tgattcgttt agaaaattac tcccagatct ttccgtttgt aacttcttag aagataaaga
     9601 aggagctcaa tcaagtcgta tggtcttttc aacttatccg accatgattg gagcgattag
     9661 tggtcaagaa gaagtaaatc aacgcccttt tactgttggg cattttgacc ttatcataat
     9721 tgacgaatct caccgttcta tttatcagaa atacaagtcc atttttgatt attttgatgc
     9781 aagaattgta ggcttaacag ctactccgcg tcaagattta gataaaaaca cctatggatt
     9841 ctttaatttg gagaatgggg ttccaacata tgcatatgat ttggaagagg ctgttaaaga
     9901 cggatattta gtagcctatc attctatcga aaccaaactg aaactaccta cggatggtct
     9961 acattatgat gatttgtccg aagaagaaaa ggaacatttt gatagcaaat ttgaagacga
    10021 tagctgtgaa aaagatattg atgggagtgt atttaattcc tttgttttca ataaaagtac
    10081 agtagaaatt gttttaaatg aactcatgac aagaggaatt cagacagcct cgggtgatga
    10141 aattggtaaa actattattt ttgctaaaaa tcatgatcat gcagaatata tcagaggtat
    10201 ttttaacaac cgctatcctg aaaaagggag cgactatgct caggtgattg attatagtat
    10261 taagcattat cagaccttga ttgatgattt taaaattgag gagaagtatc ctcaaattgc
    10321 gatttctgtc gatatgttag atacaggtat tgatgtacca gaggttgtta atttagtctt
    10381 cttcaagaaa gtacgctcta aaactaagtt ttggcagatg attggtcgag gaacccgtct
    10441 atgtaaagat ttatttggac ctgagcagga taaggaaaac ttcttggtat ttgattatgg
    10501 ggataatttt gattattttc gtgcagatcc aagagatgga gagggtcgtc acattgtttc
    10561 gttgactcag cgtttattta atatcaaagt ggacttgatt cgagaacttc agggactcca
    10621 ataccaagaa gatcagtttg cgagagcata ccgtcagcag cttgtctcgg aacttcaagg
    10681 tcgtatagag agcttaaatg agttggactt cagggttcgt atggttttag atacagttta
    10741 tagctatagg aaattggaaa gttggcagaa tctaactgct gttacaagtg aaaccattca
    10801 aaaaaatctc tctccgcttt tatttgatga agataaagaa gatgagatgg ccaggagatt
    10861 tgatttgtgg ttgcttcata ttcagttggg gcaactgaca gctaaatctt ccactgttca
    10921 tatttcccaa gtgatgaaga cggctagagc tctttctgct attggcaata tcccgcaggt
    10981 ttttgagcag gctgaaatta tcaggaaagt acaggagcct gaattttgga aagaagttaa
    11041 cttgtctgat ttggaaaaaa ttcgtcttgc tattcgagat ttattacagt ttttggataa
    11101 aacagaccgt aaaccctact atgttaactt tgaagatcgt atactctcca ctgttcacga
    11161 gaccacagca tttttgcagg tcaacgatct tcggtcttac aatgaaaaag ttgagcatta
    11221 tttgaaaact catctggatg aggagtccat ttctaagcta taccataata aaaagttgac
    11281 atctgatgat atgcttgcac ttgaaaaatt gctttgggaa aaattaggta gtaaagcaga
    11341 ctaccaaagt cattatgaaa ataaggcaat tccgagattg gttcgtgaga ttattggctt
    11401 agatagagag tctgccaatc gtattttttc taaatttttg tcggatgaga atcttaatgc
    11461 caggcagatt tcatttgtaa aattgattgt agactacatt gtagaaaatg gttttttaga
    11521 gacgaaagtg ttaacgcaag agccgtttaa atcttatggt tctgttcaac tactcttcca
    11581 acaccaacta ccagtacttc gtaatattgt tcaaatcatt gaacttatca ataatcgagc
    11641 tggagaagcg gcttaaattc taaagtgatt gccatgctga gactcattta aaattaaaaa
    11701 gagtagaaat ttatgctata tatgagaagt tttattagga agaatgtcat cgttttccta
    11761 gaatacagta tcagttgtta agtggttgat aaatttcaaa gtagatactt gtaccacgat
    11821 gtttgttgat cgagttatta acaaaagagc tactttgatt ttaaagaaat agaaaacaaa
    11881 aagccgagca agaattcaat tgcaggagaa aatgaaataa tactcaatga aaatcaaaga
    11941 gcaaactagg aaactagctg caggctgctc aaaacactgt tttgaggttg cagataagac
    12001 tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa
    12061 ccatacctac ggcaaggcga cgttgacgcg gattgaagag attttcgaag agtataaatc
    12121 ttcctaggat aaagcaaaac gcatagtatc aagggttttc aacacttgat actatgcgtt
    12181 ttctgatgtt aaagactttc taccagtttt tttaagcata attgttagtt gtagtcattt
    12241 attattcttc aaagaaaaat ggtggggcga attttttcag ttcttcaaag cacttttgag
    12301 cagtatctgc atcttcacag atgataagac agacatcatt accacaaagg gtagcgatag
    12361 cgtcagggaa gctcaaagta tcaatgatag aaccaaagga ttgagccagt ccaggaaggg
    12421 tttttagtag gacttggtgt tgaactgggc gcatccagac aagggcgtct tccatgtaga
    12481 gttcgagacg tttttcccat tttgagatgg aaccattgtt aagaacataa taagcgctat
    12541 cttcttcgcg gacttttgat aggttcatat ttttgatgtc gcgtgagagg gttgcctggg
    12601 ttacttgaat gtcgttctta gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt
    12661 tttttgtgat aagagcgcgt ataagttggt ggcggtgttc tgatttattc ataataatgt
    12721 aactcctttt agcaaggtaa ggtaagcatg gactgagcga ggtcgacagt caagtggtag
    12781 tctgtattgt cacggatggt gatttcaaag tcagtagtat agaggactaa acggagagtg
    12841 tctccttctt ttagcttgta aatagttggc tgcagttcaa attgaacatc catccattca
    12901 tctgcagtaa tatcctctac taacagtaaa tcatttctat tttgtaaatt aaggtaacct
    12961 tttgtcacga ctcgttgtgc ctctggtcta aatggcaatt cacagagatt ttccaacata
    13021 tgatagcgac cgttgtcaat ggttctagca cttaaaatag ctggataagg ttgtaggtat
    13081 ttcttttgcc caaattctag cagttgggca gataagagcc ccttgtttgt actggatttg
    13141 atacgaagat tgagctgagc gcgaccgttt aggtggagat ctttagtcac aggaaggtta
    13201 atagtaatct gattggcttt cccttgatag agctctgtat tgaaggtttg gtatgtctta
    13261 ccatagcgct caaaatcctt atctgggtac tggttttgaa tagcttgctc ttcttgacca
    13321 agtgagaagg tttcacagtt ttcttgccca ccgaagttat caagtgataa ccaagtctgt
    13381 ggagctgtat tgtcctgcca gataacagta ggaagttgaa agtctgtttc ctgtcctagt
    13441 aatttcttgg tcaataaggc atttatggac tcacggaagt caattgattg ccaattgttc
    13501 atgtaaacat gggcaccatt atggaaaaag agatgcttgt ttatatgagt aggaagagca
    13561 tggaacatct ggtaaacatg aagtggtttg acattccaat cctgagaacc atgagtaaag
    13621 acaacctctg cctttacttt atgggcattg agcagataat tgcggtcatg ccaaaactga
    13681 ttgtagtccc cagtttttcg gtctagctga gctttcactt tttctaagtc agcttggtga
    13741 gcttcattgc cacggatata gtcgccagct aagagattac gagaataggt taactcagca
    13801 agggagtcaa agtcctcacc tggataacca cctgggctag tcaccagacc gttttcacgg
    13861 tagtagttgt accatgatga aattcctgcc tcggcaatga taacttctaa accatcgact
    13921 cctgtagtcg caagaccatt ggacatggta cctagatagg aaagtcctgt tgtagcaact
    13981 tttccgtttg accaatcagc cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg
    14041 caacggccgt taagccaatc gatgacattt ttataagcct cgatttgctg gtagtctcca
    14101 ttagtcatga aacctgtcga gtctttggta ccaacacctg agacatagag attggcaaag
    14161 cctctcggaa ggaagtagtc gtttagtgta tagctagagt tgatgtgagt tagcttttcc
    14221 tcagcctctg ctataagctc agctttacct tggggttgga cgagatttag ttgaggtttc
    14281 tctagctcaa tcttgtgagg aagcttaacc tcaagctcgc cctccatctt gtagagagcc
    14341 ttgtcactag ccttgtcatt ggttccctga tgataagggc tggctgtcat gatggcaggg
    14401 atttttccat caaaacgagg gcgaataatg ctaaccttta ctaggtctga tagccctttt
    14461 tggtcagtat cgacacgaga ctcaacgtaa acgacttcac gaatgacatc ctggttagaa
    14521 aaagtagcca aactcttgcc gttaaagtag tggtagtcat tatcctccgg aataagacca
    14581 tcactaacaa gttggtcgat aagagtattt ccttttttgg tgcgagtatt gagtaactga
    14641 tagagatttt caatcaagtc accatatata atgggaaatc cagtttcttt acgaaaaacg
    14701 tcactatctt cgaagtcaac caaataagaa aagcctaaaa gttgaaaagc aacagtataa
    14761 aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg tcagcaggtc tgttttttta
    14821 tcagctgcta ggatagaaag tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt
    14881 aaaaaggttt caagtgagtc tttgtgattg gctgtatttt gtaaatcaaa gccacatttt
    14941 tttagttcag ataagacatt ttcttttgga aaattgatat aactatattg attaaaacgc
    15001 atagaacctc catatagaat gacagttaag gttattatat caaaaaaaaa gcagaaaggg
    15061 aattgttaac ttcaaaagga aataatccaa taaaaatgaa taaagtacta aattcaatat
    15121 agagaacaga gtaacaataa gaataaatag atagggtata aaagttctag gagatttata
    15181 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
    15241 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
    15301 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
    15361 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
    15421 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
    15481 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
    15541 gaaatgacag tgtttgtaga tgatcaggaa gtgaatttgc gctttttagc tctatctagt
    15601 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
    15661 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
    15721 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
    15781 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
    15841 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
    15901 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
    15961 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
    16021 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
    16081 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
    16141 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
    16201 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
    16261 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
    16321 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
    16381 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
    16441 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
    16501 ttgaaacgct ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt
    16561 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
    16621 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaagacaa
    16681 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctatattcct
    16741 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
    16801 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
    16861 gagttgcttg ctgaaataga aggtattcac cttaaaattg aagaaataga tttggaagac
    16921 aaagaaacgt tagctttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
    16981 ccaggtgcca ttcgtctgct taagcgtgtg caaccagtct gttttgaaga tgtcgtcgcg
    17041 actacttctc taaatcgacc gggtgctagt gactatatca ataattttgt ggcaagaaag
    17101 catgggcagg aagaagtgac tgttctggat ccagtactgg aggatatttt ggctccaacc
    17161 tacggcataa tgctctatca ggagcaggtt atgcaggttg cccagcgatt tgccggattt
    17221 agtcttggga aagccgatat tttgcgtcgg gctatgggga aaaaggatgc ctctgccatg
    17281 catgagatga gggcttcctt tattcaaggt tcattagaag ctggtcatac tgtggaaaaa
    17341 gcagagcagg tctttgatgt tatggagaag tttgcaggtt atggttttaa caggtcacac
    17401 gcctatgcct actcagcctt ggccttccag ttggcttatt ttaaaacaca ttatccagcc
    17461 attttttatc aggtcatgtt aaattcttcc aacagtgatt acttaataga tgcacttgaa
    17521 gcaggttttg aagtagcctc tctatccatc aacaccattc cctatcacga taaaattgcc
    17581 aacaaggcca tctatctagg tttgaaatcc attaaaggag tcagtaatga tttagctctc
    17641 tggattattg aaaatagacc ttattctaac attgaagatt ttatagctaa attacctgag
    17701 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
    17761 gaaaaaaatc gtcaaaaagt atttaataat ttagctaatc tatttgaatt tgtgaaagag
    17821 ttgggaagtt tgtttggaga tgctatttat agttggcaga aatcggaaga ttggacggaa
    17881 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
    17941 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
    18001 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
    18061 gaaaatatgg ctttcttaca ggtggatgac agtaagaaaa aattggatgt tacactcttc
    18121 tcagatttat atcgacaggt tggtcaggaa gtaagagaag gagcattcta ctatatcaaa
    18181 gggaaagtcc aatcacgtga cggtcgtctg caaatgattg cacaagaaat aagagaagca
    18241 gttgctgaac gcttttggat tcaggttaaa aatcatgact cggatcaaga gatgtcacgt
    18301 attttagacc agtataaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
    18361 accatcgttt ctccccatca ttttgtagct aaatctgatg aattagaggc gaaattgaat
    18421 ggaatagtta tgaaaacgat ttatcgctaa aattacggaa aatagaagaa ttttcaacgt
    18481 aaatgtggta taatcagtaa gaatgttaaa agaaaaagga gcataaccaa tatgaaacgt
    18541 attgctgttt tgactagtgg tggagacgcc cctggtatga acgctgccat ccgtgcagtt
    18601 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
    18661 atggttgccg gtgaaattca tcccctagat gcagcttcag taggggacat catttctcgt
    18721 ggtggtactt tccttcactc agctcgttac ccagagttcg ctcaacttga agggcaactt
    18781 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
    18841 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
    18901 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
    18961 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
    19021 tttgtaatcg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
    19081 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
    19141 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
    19201 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt
    19261 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
    19321 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
    19381 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
    19441 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc
    19501 gatattgagc tatctagctt gaataagagc ttgttataat ttacaattta gttaataaga
    19561 ccaaaaaggt catatatata aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt
    19621 tgcaactttg ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg aggacggata
    19681 ctggggtgaa aaacttgatg ttgaagcttc agctaaaaac attgctaaat tgattgaagc
    19741 tggtgctaac acattccgat tcaacttctc acacggcgac caccaagaac aaggtgagcg
    19801 tatggcaact gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga
    19861 tacaaaagga cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag aatattcata
    19921 caaaactggt gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt
    19981 gattgcgttg aacgttgctg gtgctcttga tatctatgat gatgttgaag ttggtcgtca
    20041 agttttggtt gacgatggta aacttggtct tcgtgtggtt gctaaagatg atgcaactcg
    20101 tgaatttgaa gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat
    20161 ccctaacact aaaattcctt tcccagctct tgctgaacgc gataacgacg atatccgttt
    20221 cggtcttgaa caaggtatca acttcatcgc aatttcattc gtacgtactg caaaagatgt
    20281 gaacgaagtt cgtgcaatct gtgaagaaac tggaaacgga catgttcaat tgttcgctaa
    20341 aatcgaaaac caacaaggta tcgataactt agacgaaatc atcgaagcag ctgatggtat
    20401 tatgattgct cgtggtgata tgggtatcga agtaccgttc gaaatggttc cagtttatca
    20461 aaaaatgatt atcaagaaag tcaatgctgc aggtaaagtt gttatcactg caacaaacat
    20521 gcttgaaaca atgactgaaa aaccacgtgc aactcgttca gaagtatcag acgtattcaa
    20581 cgctgttatc gacggaactg acgctacaat gctgtcaggc gagtctgcaa acggtaaata
    20641 cccactcgag tcagtaacta caatggctac aatcgacaag aacgctcaag ctcttcttaa
    20701 tgaatacgga cgtcttgatt cagattcatt tgagcgtaac tctaagacag aagtaatggc
    20761 ttctgctgtt aaagatgcta ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa
    20821 gacaggtcat actgcacgtt tgatttctaa ataccgtcca aatgctgaca tcttagcatt
    20881 gacatttgac gaattgacag aacgtggctt gatgttgaac tggggtgtta tcccaatgtt
    20941 gacagatgct ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta aagcggtaga
    21001 agcaggtctc gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga
    21061 agctgttcgc acaaacacaa tgcgtatccg cacagtacgt taagaaaaat ataaaaacct
    21121 atcatatcca gctttctagc ctgtatgatg ggctcttttt ttgtccaggg ggcaaaaagg
    21181 gggcaaaact ttcataatgg attgatactc ttcgaaaatc tcttcaaacc acgtcagcgt
    21241 cgccttaccg tatatatgtt actgacttcg tcagttctat ctacaacctc aaagcagtgc
    21301 tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga gtatgaaata
    21361 agatatgcac aaattgatta ggaaattcaa atgaatttct acaaatgttt tagcaatcgc
    21421 aatctacttg tctagattcg atctgatata ttttcgattt aatgatatgg tatttaaaac
    21481 ctccaaagta gcttgctcca ttcttttact tacgtgagtg tagatgttat ttactgtttt
    21541 agcgtttttg tgttctactc taaccattat agcattcttc tcagctagtg tactaaggag
    21601 tgtgtgcctg aaaatatggg aactaagggc tggtttatcg gtttctctag tttagtattt
    21661 gccttttgca aagtgatctt aaatgccttt ctctaaattt acatatcact attgtttaac
    21721 aaaatctaat ctactttagg tcacttattc tttttttgaa atgtagaatg aactttttca
    21781 aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc ccttttttaa
    21841 ttctccctat atagcctgac aactttcccg atggtacgaa tatggttgct ttcgtctagg
    21901 tggatgtcgg agtattcggg attgagtttt tttgaggtag ccttggcgga gtttcttgac
    21961 atagttagtg ccgtctactt ggaagatgcc gatggtatta tagtcaatct gtggggtatt
    22021 cttgataaat aggtagtcgc tgtttcttat ctttggctcc atggacttgc tgacgacata
    22081 agcgattggg tcgtagtcgt ctgggataat ggaaactcca taactaaatc gtcgtcctgc
    22141 atcaagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt ctgtctgtag
    22201 tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt tgcctctcgg
    22261 cataggtcag aactttacct tgtctgggtg gtgcccgttg gtcgtagata gattggatat
    22321 cgctaggaga atccttttga actggaggaa agagggcatc aatcaagcta ctgaatactt
    22381 taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca taatttctaa
    22441 tggtgttttt acttatacct atcttagtac ccaattctta ttgagtccaa ccattactag
    22501 tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc taaaacattt
    22561 ctaggaatta atttgccttt cctaatagag ttgttcatat cttatttcaa tctactatat
    22621 ttttcacctc taacaatcgc aatctcttct ttatccatga acgaaaacgc tttctatctt
    22681 tgtaagtaaa gcatcacacg aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa
    22741 aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagtttaa ggaaataaca
    22801 aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa tcaatatctg
    22861 taaagcagta gttaaagaaa ctttaatcca agacatttag gagaaagaaa tgaagaaatc
    22921 aagaaaatta gccacattag gaatctgttc agccttgttt ttaggcttgg ctgcttgtca
    22981 acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc
    23041 atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg tcaaatctct
    23101 cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg ttaatgacta
    23161 taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta ctcacaccga
    23221 atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt tcgttgggac
    23281 caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc caaagcttga
    23341 aaagaatgac cagttgcttt tcctagataa tgatgcgatt gataaaggaa aggtctttga
    23401 ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg aggcaactac
    23461 agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc aattcaatga
    23521 aaaagctcga atgctgtctg tagtcttgca cgacaatctg gatggcgagt atctgtttgt
    23581 aggtcacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag agaaattgac
    23641 tttcgaagaa ccctaccaag cgattaaatt tgctagtaag gaagattgct acaagtattt
    23701 gggcaccaag tatgcggatt atacaggcga gggactggct aagcctttta tcatggataa
    23761 tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag gatttttatt
    23821 tctatttttg atgacttggt gggttatttc aatcgttaat agccagaaac cactcaaaaa
    23881 tgaaacattt attggctatg tccaaagata cgatattgat gggaatggct atcaatcatt
    23941 accgtgtcct cagaactgag aggagttctt gaaatcgtaa caccactttg aacaagagtt
    24001 acttcaaccc attggctccg ccggagtaag ttgctttcgt gaacaccaaa atcagccgca
    24061 atttcttcat aagtgcggta ttctcacaca tattgaagag tggccataag aaggtcttct
    24121 aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat
    24181 acagctaaca tctcttcaaa agtggtacgc tgaacaccaa caagacgctt aaatcgtgca
    24241 tcagttagtt gtttacttgc ttcatcattc atagaactac tataccatat tttgtttcgc
    24301 aggaagtcta atgctaaaat cttatcagtg agaagatttc ttaaagttta ttctttgtag
    24361 tttcatctgt attagtacat aatttaactt agagaaaata ggaggactaa tcgaatggaa
    24421 ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac aatgtctaat
    24481 attagtgaca aagaaactac tgagaagatt ctggcgctag taccacaaga cttgattaag
    24541 cgaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg catttcaatt
    24601 gaataccctg aactctacgc tgtagctcaa acaagtggtg agattccaga aaaagaacgc
    24661 gaagaattgc gtcagattat cacaactatc tttgaacaaa agatgaataa gcatagtatt
    24721 aagtagagaa tgaaaaaata ttttattagc ggtttgggaa gcaatgccta tcatagcaag
    24781 gatttttttc aagaactaga ttcgcaggtc tattttctaa atccatatga aaagcatctt
    24841 cgagatgaaa cagaattgaa atcatggttt aaaaatgaga ttgtagagga agaatctatc
    24901 tgtctgatag gccattctct tggaggagat ttagctcgtt atttcgcatc ggaatttgaa
    24961 gaagtaaaga aactgattct tttggatggt ggctatctag atttagataa gattttacct
    25021 ttggatacag agttagagga aactaaaaat tatatcaaat ctcaaattgt ttcggactta
    25081 gctcttctta tttctaaaga gaagtccgaa gcaaagcatt ggtcagaaaa tatggagaaa
    25141 gctgtaagac agtcctatca ctggaatgtt gagtataata gatatgagtt ggctataaat
    25201 tatgaaaata tagaagcgat actccgccta cggagaaaaa tacaagcttt taagagagaa
    25261 gtgggagata ccttgtttat tagtcctcgc tatcctaatg gagctacatg gagagaggaa
    25321 gccctaaaag aattgccaga ctattttaat actatttttt tagaaaactt tggccatgag
    25381 ctttatactc aagcacctaa agaaatcgct agtctaatga atgagtggct cgcttatttt
    25441 ctatgagcta cttgtattgc tggaaatggt ataagatgaa aatctacagg ctctataata
    25501 tttgtagtgg gtaaatccac tatagatatt atggagccta ttttt
//
LOCUS       DAVLBN010000027        25378 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLBN010000027 DAVLBN010000000
VERSION     DAVLBN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.027"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..777
                     /locus_tag="VXC24_001139"
     CDS             <1..777
                     /locus_tag="VXC24_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0493256.1"
                     /translation="FGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDEY
                     MPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAG
                     TSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGI
                     TGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVI
                     KKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            787..2403
                     /locus_tag="VXC24_001140"
     CDS             787..2403
                     /locus_tag="VXC24_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493257.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            2664..3092
                     /locus_tag="VXC24_001141"
     CDS             2664..3092
                     /locus_tag="VXC24_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493258.1"
                     /translation="MSEIVEMSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            3104..3853
                     /locus_tag="VXC24_001142"
     CDS             3104..3853
                     /locus_tag="VXC24_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0493259.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            3866..5038
                     /locus_tag="VXC24_001143"
     CDS             3866..5038
                     /locus_tag="VXC24_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0493260.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIAIPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     FFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            5433..6296
                     /locus_tag="VXC24_001144"
     CDS             5433..6296
                     /locus_tag="VXC24_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0493261.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            6582..6779
                     /locus_tag="VXC24_001145"
     CDS             6582..6779
                     /locus_tag="VXC24_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0493262.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            6847..7512
                     /locus_tag="VXC24_001146"
     CDS             6847..7512
                     /locus_tag="VXC24_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0493263.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            7584..8810
                     /locus_tag="VXC24_001147"
     CDS             7584..8810
                     /locus_tag="VXC24_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0493264.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(9160..9237)
                     /locus_tag="VXC24_001148"
                     /pseudo
     CDS             complement(9160..9237)
                     /locus_tag="VXC24_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9308..9964
                     /locus_tag="VXC24_001149"
     CDS             9308..9964
                     /locus_tag="VXC24_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0493265.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            9954..10277
                     /locus_tag="VXC24_001150"
     CDS             9954..10277
                     /locus_tag="VXC24_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0493266.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            10380..11210
                     /locus_tag="VXC24_001151"
     CDS             10380..11210
                     /locus_tag="VXC24_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0493267.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            11364..12218
                     /locus_tag="VXC24_001152"
     CDS             11364..12218
                     /locus_tag="VXC24_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0493268.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            12318..13691
                     /locus_tag="VXC24_001153"
     CDS             12318..13691
                     /locus_tag="VXC24_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0493269.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            13684..14745
                     /locus_tag="VXC24_001154"
     CDS             13684..14745
                     /locus_tag="VXC24_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0493270.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            14747..15439
                     /locus_tag="VXC24_001155"
     CDS             14747..15439
                     /locus_tag="VXC24_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493271.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(15468..16037)
                     /locus_tag="VXC24_001156"
     CDS             complement(15468..16037)
                     /locus_tag="VXC24_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0493272.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            16172..16786
                     /locus_tag="VXC24_001157"
     CDS             16172..16786
                     /locus_tag="VXC24_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0493273.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            16788..18434
                     /locus_tag="VXC24_001158"
     CDS             16788..18434
                     /locus_tag="VXC24_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0493274.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            18446..19732
                     /locus_tag="VXC24_001159"
     CDS             18446..19732
                     /locus_tag="VXC24_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493275.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            19784..20317
                     /locus_tag="VXC24_001160"
     CDS             19784..20317
                     /locus_tag="VXC24_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493276.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            20395..20865
                     /gene="nrdI"
                     /locus_tag="VXC24_001161"
     CDS             20395..20865
                     /gene="nrdI"
                     /locus_tag="VXC24_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0493277.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(21158..22420)
                     /locus_tag="VXC24_001162"
     CDS             complement(21158..22420)
                     /locus_tag="VXC24_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0493278.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(22730..23188)
                     /locus_tag="VXC24_001163"
     CDS             complement(22730..23188)
                     /locus_tag="VXC24_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0493279.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(23185..23625)
                     /locus_tag="VXC24_001164"
     CDS             complement(23185..23625)
                     /locus_tag="VXC24_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0493280.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            24058..24924
                     /locus_tag="VXC24_001165"
     CDS             24058..24924
                     /locus_tag="VXC24_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493281.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
BASE COUNT         7849 a         4216 c         5370 g         7943 t
ORIGIN      
        1 tttggctata caaatcatag aattaagtta attttaagta atgaagattt aggtgcaact
       61 aatgccagaa acataggtat aaaaaattct agaggtaagt atatatcatt tttagacgat
      121 gatgatgaat atatgccaga tcgaatttta aagttgatgg cttgttttaa aaagagtaga
      181 atgaagaatt tagctttagt ttatagttat ggaataataa tttatccaaa tggtacacga
      241 gaagaggaga agaccgattt tgttggaaat cccttgtttg ttcaaatggt tcacaatata
      301 gcaggtacgt cattttggtt gtgtaaaaaa gaggtgctag aattaattaa tggttttgag
      361 aaaatagatt cacatcagga cggtgttgtt ttattaaaac tacttgctca aggataccaa
      421 attgatatag tgcgagaatt cttggtgaat tactacgctc acagtaaaga aaacggtatc
      481 actggagtga cacaaaaaac aattaatgca gatgaagaat attataatta ctgtaggaaa
      541 tattttaatt tattgagttt caacgagaga atattggtta caaagaaata ttattcttta
      601 aacataaagc ggttactatt aataggagac aaatgcaagg ctttaaaagt aatcaagaag
      661 gcaagagaag aaaaaatttt taacgaattt ctttttttga aatacatgtt attatattat
      721 tttggttttt tctattgtat atatgacaac tatgttcaat taaaatttag aaagtgagaa
      781 actattgtgt atactattat aaaatcaaat ataaaaaaat ttagtttatt aacgatattt
      841 attgttgctg gtcaattatt gctaatttat gcagcaacta ttaatgctct ggtgttgaat
      901 gaattaattg cgatgaattt agagcggttt ttgaaattgt caatctacca aatgattgtc
      961 tggtgtggga taatattcct tgactgggta gtgaaaaatt atcaggttga agtgatccaa
     1021 gagtttaatc tagagattcg aaatagagtt gccacagaca tctctaactc tacctatcaa
     1081 gaatttcata gtaaatcatc aggaacatat ctttcgtggc taaataatga tgttcagact
     1141 ttaaatgatc aggcttttaa acaacttttt ttagtaataa aaggaatttc tggtactata
     1201 tttgcagttg tgactcttaa tcactatcat tggtcattga ctgtagccac cttgttttca
     1261 ttaatgatta tgctacttgt accaaaaatc tttgcatcga aaatgcgaga agttagtcta
     1321 aatttaacta gccaaaatga agctttttta aaatctagtg agactatatt gaatggattt
     1381 gatgtgttag cgtccttgaa tcttttatat gtattgccta agaaaattaa agaagcagga
     1441 attttattaa agatggttat acaaagaaag acaactgtag aaacgttagc aggcgctatt
     1501 agcttctttc tcaatatttt ttttcagata tctctcgttt ttttaacagg ctatcttgca
     1561 ataaaaggaa tagtgaaaat tggtactatt gaagcaatag gagcactaac aggtgttatt
     1621 tttacagcgc taggtgaatt aggaggtcaa ttatcctcta ttattggtac gaagcctatt
     1681 tttttaaaat tgtattcaat taatccaatt gagtcaaata aaatgaatga tatcgaacca
     1741 aatgaggtga atagagattt tccgttatat gaagcaaaaa atatttgcta taagtatgga
     1801 gataaagaaa tattaaaaaa cttaaatttt tgttttcaac gtaatgaaaa gtatttaatt
     1861 ttaggtgaaa gtggaagcgg gaaatctaca ttattaaaat tattgaatgg ctttttgaga
     1921 gattatagtg gagaattgcg attctgcggg gatgatataa aaaaaacctc ctatttaaat
     1981 atggtttcga atgttctata tgtagatcaa aaagcttatt tgtttgaagg tacgattaga
     2041 gataatattt tattggaaga aaattatact gatgaagaaa tactacagtc tttagaacaa
     2101 gttggtttga gtgtaaaaga ttttcctaat aacattttag attattatgt tggtgatgat
     2161 gggagattac tgtcaggagg gcagaaacaa aaaattactt tagctagagg cctaattaga
     2221 aataagaaaa tagtattaat tgacgaggga acttctgcta tcgataggag aacttcgtta
     2281 gcgattgaac gtaagatatt agatagagag gatttgactg tcattattgt tacccatgct
     2341 ccgcatccgg aacttaaaca atattttact aagatatatc aatttccaaa ggattttatt
     2401 taagaatata ggggagggaa acatgagatt ctattgtgaa gcttatgagg taattactga
     2461 agagaaaaaa gtatcatttt tttatgtaga tgagaaaccc ttaaggtatc tgttatttga
     2521 ctatatattt ctactagttc tagctaaaaa aaaatatccc aatcttatga actgcacccc
     2581 aaaagttaga tttattctgt ctaacttttg gggtgcagtt cattttgcat agttttggca
     2641 ttcatcctag atatccatat aaaatgtctg agattgttga aatgtctaaa aaaatatcaa
     2701 atctaaacga taaaaaagaa tttcacaaaa agaactgtga gttgaggttt caagatagtg
     2761 ttcttgataa cataaatagt gtcccgggta caactcattt atttagttgt ttaaatattc
     2821 aaacattagt aaaaattatt ttatatattt ttcgatacaa cagttgtatg aaaatattta
     2881 attttagaga taaagagctt atctttttta ataagattgt aaatgggctg atacaaaata
     2941 ttgaggagaa tttagaggat gatattgaaa ggatattgaa atatttatat atatgtttat
     3001 ttaacgaaat attcattatt aagaataagg tgaatttttt tgatgatgtg gaatttaatc
     3061 agacacttag tgagttttta gataaattgt agagggaatg gttatgagta acaatactaa
     3121 gtatatcttt ttatctccac atttagatga cgcaattttt tcctgtggtg attatatttc
     3181 aaaattaact tcagaaggag aaattgtact tgttattact atattttctg gttacccttt
     3241 gagccaacag ctacagccct ctgctaagca atttcataag ttgtgtaacc ttgggaaata
     3301 tccgattgaa gaaaggaaga aagaagacag gttagcttgt gaacgtctac aatgtgattt
     3361 tagacactta tcgtactatg aatgtctcta taggaaagat agaaatggca attttctata
     3421 ccgtcatatc tatagtgaat taaaaaatga ggacacatta aagaatgata tcataaaaga
     3481 gctgttaatg catttagacg ataaatgtgt cgtatattgt ccgctttcac ttggtgacca
     3541 tgttgatcat gtttttgtga atagtattgg aagggcgctt gaatttatgc gttataaagt
     3601 aatatattat gaggacttcc catatgtaag tgatagtagt atggttagtt atatgggaaa
     3661 aactaaagaa ttaaaaatgt atcaagagga acttgatgaa aaacattata ttgatagaat
     3721 atcatcaata ttgtgctata aatctcagat tttgataatc tggaaatcag ttgaaaaact
     3781 tttaaacaat attaaagagt tgtatttaag gaatggggca gcttattcta ttagattttg
     3841 gattaagaaa taaggaagta gttttatgaa tatagcagta attggtttgg ggcatgttgg
     3901 gctggcctac gcgttactat ttgcatctaa atataaagtt gttgcatatg atatagattc
     3961 tgtaaaaata aataatttaa aaaagggcat tcttccatct aaaaatgaag agcttatgaa
     4021 gtttttttgc gagaataact taaatattac tttttttgat acattttctg aaattaaaaa
     4081 taatattgat tattatatta ttgcgattcc gacagattat gatgagaaaa ttggtagttt
     4141 taatacatat gaaatcgaac aaacggtatc gaagattctg agggtaaaac ctaatggaaa
     4201 gattatttta aagtcaacag ttccgatcgg cttttcaaac aaattaaaaa ggctgtttga
     4261 tacaaaaaat atcatttttg tccctgaatt tttgagagaa ggttgttcta tatatgataa
     4321 tttatatcca agtcgcatag ttgttggaga tgagacagtt gaaggaagaa aaattgcaga
     4381 gttgttcctt tcgattagta ctcatagtac tgccaatatt aaaaatgtta tgttagtttc
     4441 tcctactgaa gcagaagcaa ttaagctttt ttctaacaca ttcttagctc tccgtgttgc
     4501 tttttttaat gaactagatt tttttgctga gaggagaagt ttaaatgctg aagttgtaat
     4561 aaaaggtgtt tgtttagatc caagaattgg aaatttttat aataatcctt cttttgaatt
     4621 tggaggatat tgtcttccca aagatactaa acaattaaaa aaagaattta tagaaataaa
     4681 tgccccagtg atagaagcga ttgatatttc aaacacaaat agaaaacagt tcatagttaa
     4741 acaaatattg gaacgaaagc caaagatagt aggaatatat aaattgggga tgaaatataa
     4801 ttcagataat tacaaagagt cagctatttt aagtataatt aatgaactat tgattgtcgg
     4861 tataaaaatt ttagtatatg aaccaaattt aaacgttagt atagataacg taatttttga
     4921 aaagaatttt gaactattta caaaacaaag tgatctaatt gttgcaaata gatgggatag
     4981 gggccttgaa gcttataaag ataaagttta cacaaggggg atctggataa gagattaact
     5041 attgatatta aaaaggcaat aatttataaa atttgtacaa aaaaatgtta aattttcaca
     5101 ttttcatagt atactgttta atagaaagta ggttctttgt aaccgctcca ttataaaatc
     5161 ctttcactct tccggtatgc tattaggaaa aacataattg gaggatattt tgagctcaca
     5221 cctcatcgtt ccagtggctg ttccccaagc tcgtgtactg cccaaaaaag ttagacattc
     5281 tatttagaac gaggattgag ttctgtattg tacaaggctc ggtcctttta gagtcagctt
     5341 aaggctggct ttttcaatca ccaaagtgtc agaatgtttt gacaaatgaa cacaaataat
     5401 gatataatat gcaaaagcta ggaggtggta ggatgattga aaaaatggaa ctgggggaat
     5461 tttacaagga attacgtttg gcgagaaagc tcaagcagtc agatgtggct tgtgacgggc
     5521 taacagcttc tcagttgtcc aagtttgagc tagggcagtc catgttgtct gctgataagc
     5581 tcatattagc catccaaggg atcaatgtga cctttgatga gtttgggcac aagctcaaca
     5641 actatcaaga atctccacat atgcagattg gtagaaaggt tgtggatcgc tttgctcatc
     5701 aagatatagc tggcttagag caactgttgg aggaagtcga gcaagaacag atggcagaga
     5761 cttatcgtcg tttgaatgct attgtaatca aagatgccat ccactcacta gataaaagct
     5821 acccactagc agaggaggat agcgagtttt tgaccaccta tctctatgct atcgagtctt
     5881 ggacctggtt tgaactctat ctcttttgca atactctgcc cttcttgagc aatcaagatc
     5941 tgatcttttt atcaacctcc ttactcgaaa aatccaaaga atttaaagag ttagtacaca
     6001 atcgattgta tatgaagcaa ggactcttaa atatcttatc agaactcatg gagcgaaaac
     6061 ttttcttata catcccaatc ttcgaagccg agttggagag catgttgcgt ccgtacgatg
     6121 tttttgaaaa agtatcgtgg caatttttaa agaagatgag tgtctttctt caaacaaagg
     6181 gaagcaatca aaaagagatt gaacgcttta cccaatctct gcaggtatta gaaaatccac
     6241 aattaacatc cctttttgaa ttgcgtttgc agcaatacaa aaagcttatc gattagttag
     6301 aaatggcaaa ataataataa tctcagcaac gatcgtcaat aatgttaaaa cttgtttctt
     6361 catattactt ccctcctcat tagtaataac tttattatac cagggaaata atcaaatcta
     6421 ccaaaatcgc aaatctgaaa tttctataag aaaaaatatc aaatatgcga ttttctaaaa
     6481 taagccaatt tccgtgttat actgtccttg taaaacattt gaagcaaatc ctaggtcgca
     6541 gaagtggttt acaaatgaag ataattgaag gagtgtaaaa gatgttaaat ttacaatttg
     6601 cagaaacaat ggaattgaca gaagctgagt tggagacagg ttatggaggg gaatttggga
     6661 ataatgctgt tatcccagcc ggtgcttggg gaggtttagg aacgtcttgg tcaatcacta
     6721 atttctggaa gaaatatttt aaccatgatt cttccactgt taatcgtcgc cattattgat
     6781 attcagagtc cttgcctttt tcttgggtag ggactgtctt tatttcatag tataggagaa
     6841 aatagaatga aaaagataat ctcacaccgc tactttatta tagtttttct actagttatt
     6901 gctgaccaga agttcagtgt tttagtttta cgcagcgacc ttgttgctgg gctatctgac
     6961 tttgcctatt atctgtcgga tatgatgttg aattttcttg tggttttatt tgctcttatt
     7021 gctatgattt ggtcggggaa atggcagaaa atcaatagta gaaagtttaa aggatcctat
     7081 cttttctatt ccttcctagc tctgcttgct tttgttgctt ggaattttgt cacctttttt
     7141 cttttcccac ctactcgaaa tgaaatttct tatcaacatg ctgctcctac ttttacagga
     7201 gctacggcat ttttgatgta ttttttttat cctgtgattg caggtcccat ttttgaagac
     7261 atgatttatc gtggattagt gatgactgct ctggaaaaag gaaagaaatg ggggctagat
     7321 gtacttggtt ccgctgtttt atttggggtc tcgcacatta gtaatcacgg ttgggtcttg
     7381 acagactttg tcttctatat gggtggaggt cttatatttg cagtcttatt tagaatgaca
     7441 aagtcaattt attggcctat tggactgcat atagtctaca atggcattgg tcagcttttg
     7501 atgttactgt aattttggtt gttagtagta tcgcggtcta tccttgggga aagattccca
     7561 tttgaactta agaaggagtt gtgatgaaag tatttcttca aaatagagat tttaggcaat
     7621 taactatcaa ccagtggatt tcaacgcttg gggatacgat tttttatctg gcctttctga
     7681 attatgtggc agatgcgtct tttgcacctt tgacgatttt actcattacg atttcagaaa
     7741 cccttcccca aattttacaa atctttctgg gagttttggc agattttcaa catcatcgtg
     7801 tcttgaaata cacagtcatt agttttgcaa aatttttgct ttactctatc gtttctttat
     7861 cactttcagg gcagtctttc tccttgttgc tagtagcatt tatttgtctg cttaacctct
     7921 tgtctgacac attgagttac ttttcaggag ccatgctcac tccgattttc attagaatta
     7981 ttgggcaaga ccatctggca gaagctattg gctttaaaca gtcaactgtt agtttagtga
     8041 aaacaatcag taatatccta ggaggagtct tactaggcat tctatccatc cagtttattt
     8101 ccttactgaa cgctcttacc tttttaatcg catttttagg tatcctcttc ataaaaactg
     8161 acctcttgaa agtagaaaaa acgattagct atcaagaagg actctctgta aaatcctttt
     8221 gccagcattt gctccaatca tcaaaattga tatggaatat gaataaggtg ctcttggttt
     8281 tgtttattat ctctactagt caagcagtga taaatgttac ggttcctatt tccactctat
     8341 ttttaaggaa ccagcccttt ttgaatttac aaacaggtca atctcttgcc ttgctatcca
     8401 cttttgaact gtcagccctg attgtcggaa gccttgtaag tggctatctg caacatacca
     8461 tttccataaa aacagctctc tatgcctcac ttgtcatcca gttgcttctt ctagtaggat
     8521 ttgccacagt tcgttttgac tggattctca tctttagtac cttggatgcc tttttcgcag
     8581 gtgttctctc tcctagattg caagaactcg tttttaaaca aatacctgag gagtcaatgg
     8641 gagcagttca atcctctatc ggtgccatta cggttgtttt acctagctta tttacaatag
     8701 ctttggtaac cattgctact agctttggaa ctctggcagt tagctttgtt ttattgctat
     8761 ttcttctagt tgcctttgtt atgcttctga atattcgtga aagtatttag tggagaattt
     8821 ctataatata tgtttgagac tggattgcca gtctttttat gatggtcaaa atcaacagac
     8881 tttttctctt ttctgaatgt gttatagtag actgaatcta aaatagtacg aaacaattgc
     8941 taaaacattt atagaaatta attttacttt cccaatcgat ttgttctcat cttatttcaa
     9001 tctgctatat aatagtccat gctgtggctg gattcttttc agcctacttg tactcttcga
     9061 aactctcttc aaaccacgtc agcttcactt tgccgtagta cggttactga cttcgtcagt
     9121 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttctat ccacaacctc
     9181 aaaacggtgt tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
     9241 gtattattaa gacaatatga ggagaaagat gaaagaaaaa ggattttagg agggggcgca
     9301 ggcagccatg ccaacggctc ttggctatgt cagtatcggc ctggcctgtg gaattatcgg
     9361 tgcgccctat gtgacacttg ttgagatggg cttgatgagt ctctttgttt atgctgggag
     9421 tgcccagttt gccatgttgg cactgattgt ggttcaagct cctgtggcag ctattgctat
     9481 gacggttttt ctaatcaact tgcgtctctt tttgttgagt ttacacgcat cgacttattt
     9541 ccgtcatacc agtctttggt acaatatcgg tatgtctagt atcttgacag atgagaccta
     9601 tggcgttttg atgggtgaat tggcccatac agacaaggta aatcctatgt ggatgcacgg
     9661 gaacaatctc aacagctatg tggcttggtt tgtggggaca gtagtcggaa cggctctggg
     9721 tggcctgcta ccaaatccag aaatctttgg cttggatttt gccctggttg ggatgtttat
     9781 tggtattttt gcttcgcaat ttcagattat gcaaagacgg attcctgtcc gcaatctgct
     9841 cattatccta gcagttgttg cggtgtcctt ctttttgctc ttgacagtgg tgtctcagtc
     9901 actagctgtt ctgtttgcga cgctacttgg ttgtagcatg ggggtggttt tagatggtca
     9961 gtaagtatct tttattagca gttattttct ctggtcttgt gacctggatt ccccgtatga
    10021 ttcccttcat cttggtcaag cataagggcc tgcctgcgat tgttgagcgt tttttgaagt
    10081 ttttgcctgt ttccattatc tttgccttga ttctttcaag cgtagtgaca ggtaaggttg
    10141 ggagccttcc tcaaattaaa tggctagact tcttagccgt ctttccaaca gcttgggtag
    10201 cctttcgcta ccgcaatcta gtcggaacag ttctctttgg agtggtcttg attgccatct
    10261 tgcgtttggt cttttaaatt acccataaaa aaacttatca cagagataga tatcatataa
    10321 tggcgtaaat gctctttttc tgttaagatt ataaggtatt ctattttgga ggaaatgaca
    10381 tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc
    10441 ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc agctagcaag aaagaaatca
    10501 tcgttgcaac caatggatca ccaaagccat ttatctatga agaaaatggc gaattgactg
    10561 gttatgagat tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat aatgtcaagt
    10621 ttgaaaagac agaatggtca ggtgtctttg ctggtcttga tgctgaccgt tacaatatgg
    10681 ctgtcaacaa tcttagctac actaaagaac gtgcggagaa atacctctat gccgcaccaa
    10741 ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga ctctagtatc aagtctctcg
    10801 atgatatcgg tggaaaatcg acggaagtcg ttcaagccac tacatcagct aagcagttag
    10861 aagcatacaa cgctgaacac acggacaacc caactatcct taactatact aaggcagatt
    10921 tccaacaaat catggtacgt ttgagcgatg gacaatttga ctacaagatt tttgataaaa
    10981 tcggtgttga aacagtgatc aagaaccaag gtttggacaa cttgaaagtt atcgaacttc
    11041 caagcgacca acaaccgtac gtttacccac ttcttgctca gggtcaagat gagttgaaat
    11101 catttgtaga caaacgcatt aaagaactct acaaagacgg aacgcttgaa aaattgtcta
    11161 aacaattctt cggagacact tatctaccgg cagaagctga tattaaataa tttcttgaaa
    11221 tcatccattc tgagtaagat gggtggtttc tcagttttta gggatatagt tttaaactat
    11281 atatctgact atctaataac aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt
    11341 attattttta aggagaaaga atcatgaaaa tcaaaaaatg gcttggccta gcagcccttg
    11401 ctacagtcgc aggtttggct cttgcagctt gcggaaactc agaaaagaaa gcagacaatg
    11461 caacaactat caaaatcgca actgttaacc gtagcggttc tgaagaaaaa cgttgggaca
    11521 aaatccaaga attggttaaa aaagacggaa ttaccttgga atttacagag ttcacagact
    11581 actcacaacc aaacaaagca actgctgatg gcgaagtaga tttgaacgct ttccaacact
    11641 ataacttctt gaacaactgg aacaaagaaa acggaaaaga ccttgtagcg attgcagata
    11701 cttacatctc tccaatccgc ctttactcag gtttgaatgg aagtgccaac aagtacacta
    11761 aagtagaaga catcccagca aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa
    11821 gccgtgcgct ttacttgctt caatcagctg gcttgattaa attggatgtt tctggaactg
    11881 ctcttgcaac agttgccaac atcaaagaaa atccaaagaa cttgaaaatc actgaattgg
    11941 acgctagcca aacagctcgt tcattgtcat cagttgacgc tgccgttgta aacaatacct
    12001 tcgttacaga agcaaaattg gactacaaga aagcactttt caaagaacaa gctgatgaaa
    12061 actcaaaaca atggtacaac atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg
    12121 ctgatgctat caagaaagta atcgcagctt accacacaga tgacgtgaaa aaagttatcg
    12181 aagaatcatc agatggtttg gatcaaccag tttggtaata agaaacaggg aggtgggaga
    12241 gaaaattcca cctcttgctt ttgtatagag tatagattgt aaagaagact attcgttcat
    12301 agaaaggtag agagaatatg gtttttccta gcgaacaaga acagattgaa aaatttgaaa
    12361 aggatcatgt agtccaacat tattttgagg ttttgcgtac cttgatttct aagaaatcag
    12421 tctttgccca gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag attttcaagc
    12481 gtgttggagc tgaagtggag attgatgaga gctatacagc gccctttgtc atggcacatt
    12541 tcaagagttc gcgtccagat gccaagacct tgattttcta taaccactat gacactgtgc
    12601 cagcggatgg ggatcaggtc tggacagagg atccttttac gctttcggtc cgcaatggct
    12661 tcatgtatgg gcgtggggtt gatgacgaca agggtcatat cacagctcgc ttgagtgctt
    12721 tgagaaaata tatgcagcac catgatgatt tacctgtcaa tatcagcttt atcatggagg
    12781 gagcggagga atcggcttca acagacctag ataagtattt ggaaaagcat gcagacaaac
    12841 tccgtggggc ggatttgttg gtctgggaac aagggaccaa aaatgccttg gaacagctgg
    12901 aaatttctgg tggcaataag gggattgtga cctttgatgc caaggtaaaa agcgctgatg
    12961 tggatatcca ctcgagttat ggtggtgttg tggaatcagc tccttggtat ctcctccaag
    13021 ccttacagtc tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg tacgaagaag
    13081 tacaagagcc caatgaacga gaaatggcct tgctagaaac ttatggtcaa cgaaacccag
    13141 aggaagttag tcggatttat ggattggagt tgcctctctt acaggaggag cggatggcct
    13201 ttctaaaacg tttctttttc gagccagcgc ttaatatcga aggaatccag tctggttatc
    13261 aaggtcaggg tgttaagact attttacctg cagaagccag tgccaagcta gaggttcgtc
    13321 tggttccggg cctagaaccg catgatgttc tggaaaaaat tcggaaacag ctagacaaaa
    13381 atggctttga taaggtagaa ttatactata ccttgggaga gatgagctat cgaagcgata
    13441 tgagcgcacc agccattctc aatgtgatcg agttggccaa gaaattctat ccacagggcg
    13501 tttcagtctt gccgacgaca gcggggacag gacctatgca tacggtcttt gatgccctag
    13561 aggtaccaat ggttgcattc ggtctaggaa atgccaatag ccgagaccac ggtggagatg
    13621 aaaatgtgcg aatcgctgat tattacaccc atatcgaatt agtagaggag ctgattagaa
    13681 gctatgagta gagatattat caagttagat cagatcgatg tgacttttca ccaaaagaag
    13741 agaaccatta cagcggttaa ggatgtgacc attcacatcc aagaagggga tatctacgga
    13801 atcgttggat attctggagc aggaaaatca acccttgtac gggtgattaa tctcttgcaa
    13861 aaaccatctg cagggaaaat taccattgac gacgatgtga tttttgacgg caaggtgacc
    13921 ttgacggcag agcagttgcg tcgtaaacgt caagatatcg gaatgatttt ccagcatttt
    13981 aacctgatga gccaaaagac agcagaggag aatgtagcct ttgcccttaa acactctgaa
    14041 ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt tggacttggt tggtttggca
    14101 gatcgtgctg aaaactaccc ttcacaacta tctggagggc aaaaacagcg tgtggcaatt
    14161 gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag acgagtcaac ttctgccctt
    14221 gatccgaaga caaccaagca gattttggcc ttgttgcaag atttgaacca aaaattaggc
    14281 ttgactgttg tcttgattac gcatgaaatg cagattgtca aagacattgc caaccgtgtg
    14341 gcggttatgc aggatgggca tttgattgaa gagggtagtg tgcttgaaat cttctcagac
    14401 cctaaacaac ctttgactca agactttatc tcaacagcca caggtattga cgaagccatg
    14461 gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa
    14521 ctcaagtacg ctggatcttc aacagacgag ccacttttga atgaattgta caagcattat
    14581 caagtaatgg ctaatattct ctatgggaat atcgaaatcc tcgatggtac tcctgttgga
    14641 gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg caggtgccca agaagccatt
    14701 cgtcaagcag gcgtacagtt aaaagtattg aagggaggac agtaagatgg aatcattgat
    14761 tcaaacctat ttgccaaatg tctataagat gggttggtct ggtcaggcag gctggggaac
    14821 agctatctac ctaaccctct atatgacagt tctttccttc attatcggag gcttcttggg
    14881 gctagtggca ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt
    14941 cgtattctgg attttagaca aaattacctc aatttttcgt gcgattccct ttatcatcct
    15001 cttggcaatc ttgtcaccac tttctcactt gattgttaaa acaagtatcg ggccaaatgc
    15061 agcccttgtc ccactttctt ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt
    15121 cttggctgaa ttggatggcg gtgtcattga ggcggctcaa gcgagcggag cgactttctg
    15181 ggacatcgtg ggtgtttacc tatcagaagg tcttccagat ttgatccgtg tgacgactgt
    15241 gaccttgatt tcccttgttg gggaaacagc tatggccggt gcggttggag ctggtggtat
    15301 cggtaacgta gccatcgctt atggatttaa ccgctacaat cacgatgtga ccatcttggc
    15361 aaccattatt atcattttga ttatctttgc aatccaattc ttgggagatt tcttgactaa
    15421 gaaattgagt cataaataaa aagagccgcg tggctctttt taactgatca gattttctgt
    15481 gcaaattttt tactcaaggc ttgtccaatc aaggcaccca ctagggctcc gatgacaata
    15541 cttgcgataa atagaaggac agttccaggg tttggagcga ccatgatacg gtcgatatat
    15601 tcttgggatt ttcctcttgc cagaagagta gccatatagg ctttgggcgc aatccacata
    15661 agcaagattg gtcctgttgt actaaaggcg aaaataatga aagaaaggaa gttctttgtt
    15721 ttgtccttgt attttcctaa atgagctact tcatctgcta ggaggccaca gataattcca
    15781 ggaaggaagg aaccagcacc gtgtttagtt cccaagaaaa agagggcaat gacaaggccg
    15841 atagtggtaa tggctccaaa gcgcggaact tttgcgacta ggatcatata gacgctaccg
    15901 ccgacaaggg cagtaaaggc aggcgcataa aacatgtttc cagtttggtc aaagagattg
    15961 cccaaaagga caccaatccc catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt
    16021 aagatagatt tcttcatgaa ttgtctcctg ataatttttt cacaattctc attgtaccac
    16081 ggtttggtgg gattgtaaat ggatactaga agtttttgaa aacgcttgaa atatgatata
    16141 atggtttcat agttattttt aggggaatat catgggtaga tttttagact ttgtctttaa
    16201 tcgtttcttt ttagggatga ttgcgacagc cttcttttgg ctattaactt tagcaggagg
    16261 gattatcctt ggtctagcgc cggctagtgc caccttgatg agcttatatg cagaacatgg
    16321 ttatagcttt cgggaataca gtttgaagga ggcttggtct ctttacaagc aaaattttgt
    16381 ctcaagcaac ctgattttct atagcttttt aggtgtgggt ctagttttga cctatggttt
    16441 gtatctcttg gtgcaattgc ctcatcagac cattgttcat ttgattgcga cccttttgaa
    16501 tgtcctagta gttgccctga tctttttggc ttatacagta tctttaaaat tacaagttta
    16561 ttttgccttg tcctatcgaa atagtctcaa attatccttg attggcatct ttatgagtct
    16621 agcagctgtg gccaagattc tccttgggac tgtgctactt gtagcaattg gttattatat
    16681 gcctgccctg ctattttttg taggaattgg gatgtggcat ttctttatca gtgatatgtt
    16741 ggaacctgtc tatgaaatca tccatgaaaa attggcgaca aaatagaatg aagcagtttt
    16801 ggctacatac gcttctaaga acctatagtt cagtgatgat cattatcatt gcgagttttg
    16861 caatcttact ctcttacgct gactgggatt cacgtgaaaa ggaagcccag agagtagccc
    16921 agcgtgtaac tgctagaaca gtgagtgaaa ttgaatatta ccatagagag tcaacccaga
    16981 tagctcaggc tttagttgaa aaccaagctc gtattgaggg aatctataaa tactttagtc
    17041 ttagcatgcc agactatttt tactggcaat tagagcggaa agcttcgcct tatatatcag
    17101 tctctctgta tgaaaatgtt gatgacctct atgttcgaaa tgattttgta actggagtgg
    17161 ccattgcttt tcaagattac aaggaagtct atgtttctac taaagacaaa cgtagtggag
    17221 aaaaaatcag ggctgaggat ttcaaaccag caggaaatag ttttgccatt ccggtgtcag
    17281 atccagtgtc agatcaagat ttaggagtga tttacatctc cttggatcct gctgttttat
    17341 accatgccat tgataatact agaggtcata ctccgatggc agtaacagtg acctcacctt
    17401 ttgatacgga gatttttcat attggtgaga cagttgataa ggagagtgaa aattggctag
    17461 ttggcttaac ttctcatgga tatcaggttc aggtggcagt tcctaaaaac tttgttttac
    17521 aaggaacagt gactagctct gctttgattg tgggtttgag ccttctcttt attgtcattc
    17581 tttatctgac tttgaggcag acttttgcta attaccaaaa gcaggtagtg gatttagtag
    17641 aatccattca agtcattgct caaggcgaag aggggcgtcg gattgacatt tccgagaaag
    17701 atcaggaatt actcctaatc gcggagacga ccaatgatat gttggatcga ttggaaaaga
    17761 atatccatga tatttaccag ttagagctta gtcaaaaaga tgccaatatg cgagccttgc
    17821 aggcgcaaat caatcctcat tttatgtata atacgctgga gttcttgcgc atgtatgcag
    17881 ttatgcagag tcaagatgag ttggcagata tcatttatga attcagtagt ctcttgcgta
    17941 acaatatttc cgacgaaaga gagaccctcc tcaaacagga attagaattt tgccgtaaat
    18001 acagctatct ctgcatggtt cgctatccca agtccattgc ctatggtttc aagatagatc
    18061 cagagttaga gaatatgaag attcccaagt ttaccttgca accgctggta gaaaactatt
    18121 tcgcgcatgg tgttgaccac aggcggacag ataatgtgat tagcatcaag gctcttaaac
    18181 aggatggttt tgtggaaatt ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt
    18241 tggcaaatat ccgagaaaaa ttaagtcaga gatattttga acaccaagcc agctacagtg
    18301 atcaaaggca gtctatcggg attgtcaatg tacacgagcg ttttgtgctc tattttggag
    18361 accgctatgc cattactata gagtctgcag agcaagccgg tgttcagtat cgtattacaa
    18421 ttcaagatga gtagaaaggg agaaaatgta taaagtatta ttagtagatg atgagtacat
    18481 ggtgacagaa ggtctgaagc gtttgattcc ctttgataag tgggatatgg aggttgtcgc
    18541 aacagccagt catgccgatg aagctctaga atatgttcag gaaaatcctg tcgatgtcat
    18601 catttccgat gtcaatatgc cagacaaaac agggcttgat atgattcggg agatgaaaga
    18661 gatcttacca gatgctgcct atatcctgct ctcaggttat caggagtttg attatgtaaa
    18721 aagagcaatg aaccttagtg tggtggacta tttggtcaag cctgttgata aggtagagct
    18781 gggaaatctg ctggagaaga ttgcaggtca gctcggcgag agagggaaga aaagtcagac
    18841 tcttagtcaa gaattagacg aggctggatt tgttagttat ttaggggata aggagaattg
    18901 gtggataggt ctatccaagg aaaaacaagg ttccttcacc attccctact atgtcttggg
    18961 tcaagactgg cagattttca tttctggcca acccttagat ggcttagtcg ttactccctt
    19021 tgaagctccc tatcaagaac actttgaacg ctggaagctg aatgctgaga aaaccctctt
    19081 ttacggttct gtaaatctgc agcagtctga gagtctcttt gcctattacg aaccgattta
    19141 tagggttatc attcagggaa atctcaatca aatcgtagaa gagttaaatc tcttggagaa
    19201 ggtagttctt gaaaatacgc cgcgtgttcc gattactaaa cagcttttta ttcagtttgt
    19261 catggatgtt ttccatttat ttgaacatct caaagctgat gacctgacag acatcgttaa
    19321 aaccattcat gctattcaat ccttcgatga attggttcct tatatcaagg aaactctgac
    19381 cagctttttc ggtcaatacc gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg
    19441 tcgtgattac caaaaagagc tttccctcaa ggatatcagt aaggctctct ttatcaatcc
    19501 tgtctatcta gggcagttga ttaagcgtga aaccgattcg acttttgcag agttactaaa
    19561 caaacaacgt attaaggctg cccagcagct cttgctttca actagtgaca gcatcgaaga
    19621 tatttgttat gctgttggtt acagtaacct tggatatttc tataaagttt tccgaaaatt
    19681 gtgcggaaaa tcgccaaaag cctaccgaaa acaggtagaa actatactat aagatttgta
    19741 ttcctttaca aaatgtgcta taatattatc aggaggttct atcatgaaaa agaaaccaat
    19801 ttatctatgg gtcttgctaa tcttgtctgc ccttatttca gttccgtctc tgtttggaat
    19861 tgtgagtccc ttgcctagta aagaagccct tcgtgctgct cagaaacaag ttgcaggggt
    19921 caatgctcag caattagaag accagcttaa ttatacctat agagtagcag aagcatctca
    19981 ttctattttt aatgttgctt tgattgtgct atctactatt ttagtggtcg tagcgattgt
    20041 cttccttgtt cgtaaaaatt tgcaatatgc aaactatact tacgttggct atgttttgtt
    20101 agctattatt ggttcgattt atggctatgt tggtttacaa gatgctgtgc agttggttca
    20161 agatgagagc atgcgtttga cagtgagtat tggttcaaaa gctgttagca ttttctatat
    20221 cgtcatcaat gttctcttcc tagcccttgt cttctataag atgtggcgac aacagaaagc
    20281 cttggcagaa gaagaggaaa cagaagagct tgcctaagta ttgacaaaaa agaactatca
    20341 agatacaatc ttggtagttg ttttttgatt atagataaaa tcatggaggt acatatgaag
    20401 acaatttctt tagtttatat tagtttgagt ggcaacactg aaagttttgt gacgcgcttg
    20461 aaagactatc tcttgtccca gtacaaaggg attgaggttc aaaagattca tatcaaggat
    20521 ttggtcaagg aaggcaaaaa tttctacgaa atggaccatc cctatgttgc ttttttgccg
    20581 acctatctcg aaggtgggaa tggcgtggat aacggagatg ttgagatttt gacgacaccg
    20641 gtgggagatt ttattgccta tggtaacaat gctagtaagt gttttggtgt ggttgggtca
    20701 ggaaatcgta actttaataa ccaatactgc ctaacagcca agcaatacag tcaacgcttt
    20761 ggctttcctg tattggctga ctttgaaatg cgaggcatgc tggaagatat caaacatgtc
    20821 gcagctatta tcgcagattt gtatgagttg gaaaaggaga attaatactc aatgaaaatc
    20881 aaagagcaaa ctaggaagct agtcgcaggt tgctcaaagc acagctttga ggttgcagat
    20941 agagctgacg tggtttgaag agattctcga atagtataaa gttcttataa gaggtggttg
    21001 aagttgttca actgtttttt gagtataaac agtctttaag aacgtaaaaa agcataagtt
    21061 caggtcttca aaaccttgtt cttatgcttt ttatcataga aatatttgct gaattttctc
    21121 ttgaaatgaa accttatctt catctcgcgc ttgtccctta ccctgctttt ccgattgcga
    21181 gtgcgtagat aaagaagatg gcgaagccaa agaggaaaat caatcccgca atggcaaggt
    21241 gtttgagcca agaaggaaga tttttgtttt cacgtgttac caaggcgtaa ttcaaaagag
    21301 caaagaaagg tgttgtcagg aaagagccaa tcatggcaaa gcggagcatg gttgaaacct
    21361 gaccagcgaa gaacttgata atgatgatac cgatgatagc agtgatggtc atccagatgt
    21421 tcaaagattt acgattatcc tctttttgac tgattagcag tcggagagat tcctgattaa
    21481 cgcgagaata gccatcgata acagttataa ctgttccaaa gatacagagg aaggcaataa
    21541 aggtaatcaa gtaacgggac cattcgccaa gaacagaggc atacatgccc acgaattgag
    21601 agatgtattt ggctgaagca gcttcaaccg cctgccctgt aggatactga atcagtgctc
    21661 ccagtgccac aaagaagacg gctaggatag ctgttccaat ataaccagtg ttaaagtcaa
    21721 acagagcgtc ttctgtgtta aagttgacgg tctttctctt ttcagctgac caaagtgaat
    21781 tgatggctga aatttcaata ggagccggca tccatcctag gagggagacg atgaagggca
    21841 gagctgccat ttgccaaggt gtcttctcga caaaatcaga actgtattct ggatgcttga
    21901 ccgccgcaat gataactgca agaacagtcg caatggttaa ggcagacata atccatttga
    21961 ccatgccgtc taaaagtttg tagcctccaa agagtagcat agcccaaatg attgcaacga
    22021 gaatgaggga ccactgagta atgctaagtc caatcattgg gaaggcactg gcgatgatag
    22081 ctgagcacag aatggcaaca ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa
    22141 agaaaatcca gagatagagt tttccttttt cggcataacc ttcaaccaaa gtctttccag
    22201 tatcagctgt gtattcagca ccaaaacgga aaaatggata tttaaagaca ttggctaaga
    22261 tgaccaagag aagtagagac caaccgtaag aaccgccagc ttgagttgag gatacaatgt
    22321 gggaacctcc aacagcggca gttgccatta ggattccagg tcccattgct tttagcttgc
    22381 ttgcccaggt tgattgattt aaggaaatag cttgcgacat gataaatact cctttttgaa
    22441 ttttcagaat aatctgtata tgtaatctat attctacaaa aaattttgga aaaatgcaag
    22501 agtattttga aaaaagatag aaaatttaca aagaaaatct gaaataactg ttatgatata
    22561 gaggattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
    22621 ctgtcctgat cgatttatcc tgttcttatt tcatttcact atagtaaggt gcagcaggat
    22681 aaagaaaaac cgagaagttt ctttctcgga tttgcttatt atgaggttcc tattttctat
    22741 gctccaagag ttgattgatg tgatctactt ttttagcctc tcttttatag agaatagccc
    22801 agatgatgag atagacaatc gcaaactcga taatgagctg gaggtagaaa atccagtgga
    22861 aagggaacca accagcaaga gttgctagtg ggacaaagcc agccagcata aggaagaaat
    22921 gagtcagagt ggcacgaagc atgctccagt cacggctaaa taagcggttg ccaaagttga
    22981 agagcatacc gatggttgcc cagataagtg tgcagtagag caagaccagg gcaccgtgaa
    23041 cctgatgctg atccatcact tggccgatga gagagtaggg atttagtggt gcgtaggtat
    23101 ttggtgcata aatgagtgaa aagaggatag agaggatgag gccgataaga acaccggtag
    23161 ctgcatcgtg aaatacttgt tttttcatag ttctaatttc tccttgatgg tttttagata
    23221 acggcgtgaa gagtaggtga agctttcgtt tttcaagaaa atttctacca gaccgtttgg
    23281 cgtgagcttg aggtgagaga tggaatcgat attgatgatt tctgattggg aaatttggat
    23341 aaaattggtt ggcaagagtt taagaacctg atagagtcgc aaatcaatgc tgtaggtctg
    23401 actcgcggtt tctgctagaa ccttccgatt ctcgatatag aagcgctgaa tcttgccaat
    23461 ctcaactaga tagacctgat catcgatttt tcctttgatt ttttctcttt ggtccagatt
    23521 ttctgcgaac tcgatgactt tctggacttt ttcggtttct tgaggtgctt ggacaatcag
    23581 cttttcctcc tcgtaagtct cactaatctg tagttctact ttcatagttt tctctccttt
    23641 tcagttatac aaggttgtga tcacttcctg tatatcctta ttaaacacta ttttatagcc
    23701 catggcaagg aaccttgtct atgtggaggg attgggctcc tatgtggtgg agcttttctg
    23761 ttctttctga aatatggtat aatagcacta atcaatttct aggaaaatag atacggaaag
    23821 gggctgaaag aactagggga acagttggaa ttagaaagtg ataggtatga aaagtggcgt
    23881 tgaagctgaa taagtttata aagcgtttga atgaagaaat ggaaagtaaa taagttgacg
    23941 atgaattaca aaatagattt tatctacaat ttgtatcttt caaatcattg atttgaattt
    24001 tagatttaat catgttacaa ttaaaactga aatcaaatag aagaggaaaa tgcaaacgtg
    24061 ggcacactat tagcaacaag attaaaaaat agacggaaag aattaaaaat gtctcagcga
    24121 gaactagctg aaggtatctg taaacagggg caaatcagtc gattagagag cggagagttt
    24181 acccctggag cggatttcct gaatgccctt gctaagaagt taaaagtcag tatggattat
    24241 ttttttgatg agcaggttgt agagaaagtt gaggagttat cagaatttaa gaaattagca
    24301 cagacattta ttacaaatcg caattatgag tctttgaaat atatatatga attggagaat
    24361 gtaaaagctc accgcctatc tttagcagat aaaatctaca tggaatggat aaaatctctg
    24421 atagattttt atttttacgg acagaaagaa gatgcgattg tacgattaga gggggtatta
    24481 tcacagttaa gtgtatctga tttgaactat ctccaagttt caaacaccct attcaatttt
    24541 tattatgata ttggagattt aggtcgtttc aataaaattc gtgaaaaact agagtatcaa
    24601 gtaaatcacc tcaatttgag tacaatcgaa gagttagaac tatctattaa gtttaactac
    24661 aacgtttgtc gttatctatg gttacagaaa aatattgaag aagctattac taaaattaca
    24721 gctactataa aacaatgtaa ggcttacaga acgaattatc ttttggctga tttgtactta
    24781 ttgatgggaa atgtaagtga aaatttttct tctaaaagtt cggtgaaaga atattttgag
    24841 acggcatatt ttctatacaa acttgaggag aacatgtcaa tgactctgaa agttgagcat
    24901 tacattgcag atataacaga ataatgaata cggtgttcaa gtgagcatcg tttttcaaac
    24961 ctagttcaga tacaaaaaag tatcaaacaa aaaaaaataa aaaaacatta taaaaacaat
    25021 tgacaagcta attttgaagt gataaaataa atgcaagaaa acaaaaggag aggtatatga
    25081 gaagtttgtt taagaaaata gttgctgtat tagttattgg cttaattctg ttaggaattg
    25141 cgagaacacc tcaagttcat aagatggcta gagggattga tcctggtcct gcgaatttta
    25201 tttagaaatc aatttctact aattgagtac taattgagta ttaatgggta aaaagattgt
    25261 atggataaga aaaatttact tgtattggtt actggttcgg taggtgccag taatgtagat
    25321 acatacttat attatataaa aaaattctat aatgttaaag tgatactttc tgaaaatt
//
LOCUS       DAVLBN010000028        24999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLBN010000028 DAVLBN010000000
VERSION     DAVLBN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.028"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            186..416
                     /gene="blpU"
                     /locus_tag="VXC24_001166"
     CDS             186..416
                     /gene="blpU"
                     /locus_tag="VXC24_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0493282.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1131..3284
                     /locus_tag="VXC24_001167"
     CDS             1131..3284
                     /locus_tag="VXC24_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0493283.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3297..4646
                     /locus_tag="VXC24_001168"
     CDS             3297..4646
                     /locus_tag="VXC24_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0493284.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4816..5523
                     /locus_tag="VXC24_001169"
     CDS             4816..5523
                     /locus_tag="VXC24_001169"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0493285.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5525..5668
                     /locus_tag="VXC24_001170"
     CDS             5525..5668
                     /locus_tag="VXC24_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0493286.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5725..9450
                     /locus_tag="VXC24_001171"
     CDS             5725..9450
                     /locus_tag="VXC24_001171"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0493287.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9543..10985
                     /locus_tag="VXC24_001172"
     CDS             9543..10985
                     /locus_tag="VXC24_001172"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0493288.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11204..12226
                     /locus_tag="VXC24_001173"
     CDS             11204..12226
                     /locus_tag="VXC24_001173"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0493289.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12223..12768
                     /gene="purN"
                     /locus_tag="VXC24_001174"
     CDS             12223..12768
                     /gene="purN"
                     /locus_tag="VXC24_001174"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0493290.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12852..13361
                     /locus_tag="VXC24_001175"
     CDS             12852..13361
                     /locus_tag="VXC24_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0493291.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13386..14933
                     /gene="purH"
                     /locus_tag="VXC24_001176"
     CDS             13386..14933
                     /gene="purH"
                     /locus_tag="VXC24_001176"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0493292.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15055..16317
                     /gene="purD"
                     /locus_tag="VXC24_001177"
     CDS             15055..16317
                     /gene="purD"
                     /locus_tag="VXC24_001177"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0493293.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16720..17208
                     /gene="purE"
                     /locus_tag="VXC24_001178"
     CDS             16720..17208
                     /gene="purE"
                     /locus_tag="VXC24_001178"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0493294.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17195..18286
                     /gene="purK"
                     /locus_tag="VXC24_001179"
     CDS             17195..18286
                     /gene="purK"
                     /locus_tag="VXC24_001179"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0493295.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18296..18523
                     /locus_tag="VXC24_001180"
     CDS             18296..18523
                     /locus_tag="VXC24_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0493296.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18586..19884
                     /gene="purB"
                     /locus_tag="VXC24_001181"
     CDS             18586..19884
                     /gene="purB"
                     /locus_tag="VXC24_001181"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0493297.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VXC24_001182"
     CDS             complement(19939..23877)
                     /gene="strH"
                     /locus_tag="VXC24_001182"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0493298.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(24192..24908)
                     /locus_tag="VXC24_001183"
     CDS             complement(24192..24908)
                     /locus_tag="VXC24_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0493299.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
BASE COUNT         6884 a         4893 c         5938 g         7284 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 cagtacgagg tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg
      361 ctgcgggagg agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat
      421 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
      481 tttaattaga aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa
      541 ataatcaaaa ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag
      601 tcttatagta acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc
      661 tattctgact aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa
      721 ttgaagtaat aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt
      781 gcctagggtg acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac
      841 tcttgttctg cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg
      901 ggaaggaagt ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt
      961 atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact
     1021 gacttcgtca gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt
     1081 cctagtttgc tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg
     1141 ggaaacgtca ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca
     1201 tggtttttgg ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga
     1261 cgaccatgga tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg
     1321 agacgcgagc cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt
     1381 ttgttgccca tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg
     1441 ataaggatag cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac
     1501 gtgagcgttt tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact
     1561 ataagcctta taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc
     1621 agcgtggctt gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg
     1681 tgggttctta ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga
     1741 cactagggat tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt
     1801 acgctcagga gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt
     1861 cctatatcaa gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg
     1921 agatcgtgtc tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc
     1981 tttcgatttt cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa
     2041 ataccaatct ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg
     2101 cctttatgaa gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt
     2161 cttcttctat cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa
     2221 gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct
     2281 atagtcgagc agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg
     2341 tcggcattct ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt
     2401 tgattaccta taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc
     2461 tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag
     2521 tagcttctga gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata
     2581 tgaccttcaa gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca
     2641 atttaaccgt tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga
     2701 cgactttggc caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg
     2761 gtggtgtcaa tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc
     2821 ctcaacagcc ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg
     2881 aggggacgac acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata
     2941 tcgagcgcat gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag
     3001 gtggtcaacg tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga
     3061 ttttggatga ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc
     3121 tcatggcttt ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga
     3181 cagagaaggt agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt
     3241 tgcttgcaca gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga
     3301 aaccagaatt tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta
     3361 gtgtgattgt acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag
     3421 agaaggagat gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata
     3481 tccagtcaac tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta
     3541 agaaggggga tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct
     3601 atgccagtca gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga
     3661 gcctgcaaga aggggagaac cactttccag aggaggataa gtttggctac caagccacct
     3721 ttcgcgacta catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga
     3781 ccatcgcgtc ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca
     3841 gtcaaacaga ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg
     3901 cttccttggc cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg
     3961 aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt
     4021 tagaatctag tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct
     4081 atgcgtcagg gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg
     4141 gtcaggaatt gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac
     4201 agggaaatct tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta
     4261 atcctgagac cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc
     4321 catctttgga aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag
     4381 caagaatcaa ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac
     4441 ttttcctaga ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga
     4501 atttctttaa aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt
     4561 acggggtgga aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt
     4621 tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac
     4681 tgtgagaaag attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt
     4741 attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga
     4801 aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat
     4861 acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac
     4921 ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt
     4981 atttttgaga aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac
     5041 acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat
     5101 actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg
     5161 attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat
     5221 gtgaaattcc tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt
     5281 cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt
     5341 aagctagagt tcggttttga caaggatggc aagattatct tggcagacga attttcacca
     5401 gataactgcc gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga
     5461 ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa
     5521 taatctgttt gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt
     5581 cccccagacc ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt
     5641 ctgggaaaag ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga
     5701 gctgaaataa aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat
     5761 tttcaggtca agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc
     5821 ttgaaaagta ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt
     5881 gcacctgcag agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta
     5941 tctgtgcagg cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag
     6001 tttgaccagc gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac
     6061 gtgacagtca acacagccca actttacttg gtgaataaag atattgatgc gactgagttg
     6121 gaagctgtca aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca
     6181 gggattgcca agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt
     6241 gaaagctata cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa
     6301 gtggatgatt tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag
     6361 actgaactca aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag
     6421 acagagttga aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc
     6481 tatgacaagt atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg
     6541 atggatatgg cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg
     6601 gaagtctctg acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc
     6661 aaggaacctt ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag
     6721 ccatttggtg gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt
     6781 tcctatgttt accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg
     6841 gaaactcgtg ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat
     6901 tcttcatatg gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca
     6961 ggctttgtag ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat
     7021 gttgtccgtg aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt
     7081 cgtgatggtg tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag
     7141 actgctggtg ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc
     7201 ttccgtaatg gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc
     7261 gtctgtgtgg ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct
     7321 cttaaatacc agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg
     7381 gcggtcgtgg ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat
     7441 attgatgctg ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat
     7501 ggtgagacaa tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt
     7561 gtcgatgcca aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct
     7621 gaaacactgg aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa
     7681 ggattacaga ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt
     7741 ggtcgttacc aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt
     7801 gtgactcata ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct
     7861 ccataccacg gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt
     7921 gccaactggt ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa
     7981 gcagagcgtt tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag
     8041 cttggcttgc catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc
     8101 gttccgccaa ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct
     8161 ccagaattta aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca
     8221 gagattgatt ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac
     8281 cataaagtga cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt
     8341 gctacctttg gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg
     8401 acagctcaat taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag
     8461 attggacaaa cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac
     8521 aagcttgaca gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa
     8581 gcgaaagaac tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa
     8641 aaggttgaaa aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat
     8701 tcagctaagg ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg
     8761 aatgaagaag ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat
     8821 attctcttct ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt
     8881 atcgtcaata tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt
     8941 ggtggcttga ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta
     9001 ccatacggaa actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc
     9061 aaccaacacg tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg
     9121 gctggtgtgc aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt
     9181 gtcgtgacgg ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac
     9241 gttgacttta acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat
     9301 gccatcgaag gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa
     9361 cgttatgagg atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca
     9421 tcagcggtta aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca
     9481 gtaatgtaaa agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa
     9541 aaatgacata cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac
     9601 atccagatgc tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg
     9661 agggggcagg aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc
     9721 ttttatcaga agttttcaga aatccagcca atttggataa attgacagga gctggtgcga
     9781 ttgggcatgt gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc
     9841 tcttccgttt tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag
     9901 cctctctcaa gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg
     9961 aaatcttggc tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg
    10021 aagcgctcag ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga
    10081 ttgcggctct tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag
    10141 cggtggttgt ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg
    10201 atttgaagcc aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata
    10261 cagatgatac ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt
    10321 ctaatatcca cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc
    10381 gagaatttaa gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg
    10441 ctatgggatt tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat
    10501 acacccagcg aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga
    10561 aactgtctgc tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca
    10621 ttgtacgtgg aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg
    10681 aggttcacgt tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata
    10741 tccagacccg tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca
    10801 ttggtgcgga cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg
    10861 aaacagatgc gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc
    10921 ctctctatga ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca
    10981 agtaggcgac agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat
    11041 atgcctcacg tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc
    11101 tataggatca aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa
    11161 aatacgtcgc agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc
    11221 gtacgctcaa tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa
    11281 gcacgtggct cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat
    11341 gtttgacctt tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt
    11401 cggaaccaag ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg
    11461 tgtggccatg tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga
    11521 ctacgtagcg acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc
    11581 agaaggttgt gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg
    11641 catgtacggc gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc
    11701 tcaaatcatt gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag
    11761 tgggattcac tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga
    11821 ggaagtccta ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg
    11881 tatctatgtc aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca
    11941 catcacaggt ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc
    12001 tgaaattgat gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg
    12061 tcagattaaa cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc
    12121 ggtcagccct gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat
    12181 tggtcgcatc gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt
    12241 tttgcctctg gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt
    12301 gtcttttcag accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg
    12361 tcctatgctt ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc
    12421 gaactcttgg aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt
    12481 ggaccaacct tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg
    12541 ccagaatttc caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct
    12601 ggtgtgacca ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt
    12661 cgtgtgccac gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca
    12721 gagtacaggt tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat
    12781 tcatatgata tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg
    12841 aggtatttgt aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga
    12901 tgttattaac ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt
    12961 tcttagctcc aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa
    13021 aaattgtttt tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt
    13081 tccctttgat aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta
    13141 gtttattgtt tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt
    13201 tgactttaaa tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag
    13261 tgttcaaatc acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg
    13321 cttatcttgt tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga
    13381 atataatgac taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg
    13441 cccaagaact aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc
    13501 ttgataatgc tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga
    13561 tggatggccg tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg
    13621 atttggatag ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag
    13681 tggtcaacct ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg
    13741 cagttgaaaa tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg
    13801 ccagtgttac agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag
    13861 caaacggcga aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca
    13921 cagcggctta tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc
    13981 ctgaaaaact cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc
    14041 aacaagacgc ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca
    14101 aacagctcaa cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc
    14161 gtatcatccg tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat
    14221 gtggtatcgg ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc
    14281 cagtgtctat ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg
    14341 agaagatgca cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc
    14401 tagctatttt gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc
    14461 aagaggctag cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa
    14521 atcaagacgt ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa
    14581 ccgagacaga agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa
    14641 atggtattat cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc
    14701 gtgtggcttc tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc
    14761 ttgcttcaga tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa
    14821 ttaaggccat catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg
    14881 ataaatatgg cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata
    14941 aaagggaaga aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta
    15001 aaacgaactt ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa
    15061 ctgcttgttg tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca
    15121 aaagacgtgg aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg
    15181 gaattggtaa atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat
    15241 gatgttgctt ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat
    15301 tttaaccaag ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg
    15361 tccaaggatt tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc
    15421 acattttcag atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta
    15481 gtcaaggcgg atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa
    15541 gcggtcgaag ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc
    15601 gtggttattg aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt
    15661 gataagttct acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa
    15721 gggcctaaca cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta
    15781 gttgatacag cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt
    15841 cgcccttatc tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc
    15901 attgagttca acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc
    15961 tctgactttg ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg
    16021 acggacaagg gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat
    16081 gaaaggggcg ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg
    16141 gctaagtttg cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc
    16201 gttaccacag cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa
    16261 caaaaaatag aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga
    16321 tataagaata acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca
    16381 gaacagtgaa tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat
    16441 gaaaccgaag gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa
    16501 aattcacaaa atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac
    16561 aatcaccgcc gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa
    16621 gaccttgggt ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa
    16681 gctaaggtga ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc
    16741 atcatgggct caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc
    16801 ttcggtgtag cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc
    16861 aaacatgcag aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc
    16921 gcagcgcatt tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca
    16981 gtcaagtctc gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt
    17041 ggggtgcctg ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt
    17101 gccctccgtc tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct
    17161 gaagaacaag gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat
    17221 tatcggtggc ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa
    17281 ggttatcgcg ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt
    17341 ggcaccttat aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac
    17401 ttacgagttt gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact
    17461 ccctcaagga acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt
    17521 gtcaaacaag gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt
    17581 ggcagatatc gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg
    17641 tcatggacaa aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga
    17701 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    17761 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    17821 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa
    17881 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    17941 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    18001 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    18061 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    18121 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    18181 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    18241 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    18301 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    18361 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    18421 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    18481 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta
    18541 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    18601 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    18661 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    18721 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    18781 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    18841 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    18901 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    18961 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    19021 gagccgacaa cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc
    19081 gagcgtttcg agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg
    19141 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    19201 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    19261 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    19321 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    19381 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    19441 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    19501 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    19561 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    19621 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    19681 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    19741 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa
    19801 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    19861 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    19921 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    19981 ggacatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    20041 tttctctgtt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    20101 agttgatgga gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc
    20161 ttgtccgttt tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac
    20221 ggcttcctgt gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt
    20281 gctcacagag tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt
    20341 tcctttgagt aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg
    20401 gatatccagt ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg
    20461 agttacagga gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc
    20521 aaggactgtt tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc
    20581 acctttgact cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt
    20641 cttgataact tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac
    20701 attggcagcc acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc
    20761 ttgaagagcg gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt
    20821 gaggttgtaa tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata
    20881 tccttctaag tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg
    20941 gaagtagtct ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt
    21001 gtattcagcg cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc
    21061 tacttcagga tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat
    21121 agctttcttg aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc
    21181 accgttggta ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt
    21241 atatccccac cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc
    21301 gtccttgtct tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt
    21361 ggccatagct gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt
    21421 gaggtagtac cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt
    21481 gaaaatcttt gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa
    21541 gttcatcgct tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc
    21601 ttgaggattt ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg
    21661 actgttaata gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt
    21721 tacttctgcc tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc
    21781 gataatagct tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat
    21841 atcatcgagt agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc
    21901 gagctcactg gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc
    21961 agcatcgatt gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc
    22021 ttctttttga gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat
    22081 ggcttgatca atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc
    22141 tttttcagct tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg
    22201 tacctcgtta agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc
    22261 atttgcaaaa tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt
    22321 gtcagcccaa gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg
    22381 tacagaagtg attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc
    22441 ttggccatca gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg
    22501 gtgacctttt tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt
    22561 ccacatagaa acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta
    22621 gataccgtcg ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc
    22681 attggcgtag gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta
    22741 tttatcagct tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc
    22801 aagtccgatg ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag
    22861 ggcttttgta aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt
    22921 cccaaaatag ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc
    22981 atccatgtgt ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata
    23041 gttaatcaga tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata
    23101 atcatttgta cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt
    23161 agctgtgatg ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg
    23221 taaatcagtg tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga
    23281 gaaatattta cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac
    23341 agttgcagca cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc
    23401 atctttttta gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac
    23461 ctctttcgct tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt
    23521 ttcagcagaa gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc
    23581 ttgtggtttt tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt
    23641 ttctacagtt tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt
    23701 ttcggatgat tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt
    23761 aggagtaact ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga
    23821 agctgctcct acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc
    23881 aaaacctcct gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt
    23941 atttcttata ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa
    24001 atataaaatt taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt
    24061 ataatttttg gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag
    24121 gtaagcgcta cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc
    24181 aggctttctt cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat
    24241 cgtttgtaag tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta
    24301 gtttgtagga cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga
    24361 gttggaaaga ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag
    24421 tctaacttga aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg
    24481 atatattgtt ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg
    24541 atacgttcaa tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca
    24601 agcttgtttc cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt
    24661 tcaatatctg aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt
    24721 ccttgttggc ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg
    24781 atagagctga catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg
    24841 ctaaactgcc cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga
    24901 attgccatat ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa
    24961 aaaatagtag tcttttgaat aaaaaattag aataatagt
//
LOCUS       DAVLBN010000029        24071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLBN010000029 DAVLBN010000000
VERSION     DAVLBN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.029"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(286..1893)
                     /locus_tag="VXC24_001184"
     CDS             complement(286..1893)
                     /locus_tag="VXC24_001184"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0493300.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(2283..2870)
                     /locus_tag="VXC24_001185"
     CDS             complement(2283..2870)
                     /locus_tag="VXC24_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0493301.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2998..3447)
                     /locus_tag="VXC24_001186"
     CDS             complement(2998..3447)
                     /locus_tag="VXC24_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493302.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3452..3841)
                     /locus_tag="VXC24_001187"
     CDS             complement(3452..3841)
                     /locus_tag="VXC24_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0493303.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3869..4495)
                     /locus_tag="VXC24_001188"
     CDS             complement(3869..4495)
                     /locus_tag="VXC24_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0493304.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4509..5072)
                     /locus_tag="VXC24_001189"
     CDS             complement(4509..5072)
                     /locus_tag="VXC24_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0493305.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5237..5386)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5446..5949)
                     /locus_tag="VXC24_001190"
     CDS             complement(5446..5949)
                     /locus_tag="VXC24_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0493306.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6142..6972)
                     /locus_tag="VXC24_001191"
     CDS             complement(6142..6972)
                     /locus_tag="VXC24_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0493307.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6957..8639)
                     /locus_tag="VXC24_001192"
     CDS             complement(6957..8639)
                     /locus_tag="VXC24_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493308.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(8741..8998)
                     /locus_tag="VXC24_001193"
     CDS             complement(8741..8998)
                     /locus_tag="VXC24_001193"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493309.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9005..9553)
                     /locus_tag="VXC24_001194"
     CDS             complement(9005..9553)
                     /locus_tag="VXC24_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0493310.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9568..10416)
                     /locus_tag="VXC24_001195"
     CDS             complement(9568..10416)
                     /locus_tag="VXC24_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0493311.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10604..11953
                     /gene="trkA"
                     /locus_tag="VXC24_001196"
     CDS             10604..11953
                     /gene="trkA"
                     /locus_tag="VXC24_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0493312.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11957..13396
                     /locus_tag="VXC24_001197"
     CDS             11957..13396
                     /locus_tag="VXC24_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0493313.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13521..15200)
                     /locus_tag="VXC24_001198"
     CDS             complement(13521..15200)
                     /locus_tag="VXC24_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0493314.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(15269..16681)
                     /gene="lacG"
                     /locus_tag="VXC24_001199"
     CDS             complement(15269..16681)
                     /gene="lacG"
                     /locus_tag="VXC24_001199"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0493315.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16691..17035)
                     /locus_tag="VXC24_001200"
     CDS             complement(16691..17035)
                     /locus_tag="VXC24_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0493316.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17203..19089)
                     /locus_tag="VXC24_001201"
     CDS             complement(17203..19089)
                     /locus_tag="VXC24_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0493317.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19091..20413)
                     /locus_tag="VXC24_001202"
     CDS             complement(19091..20413)
                     /locus_tag="VXC24_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0493318.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            20581..21804
                     /locus_tag="VXC24_001203"
     CDS             20581..21804
                     /locus_tag="VXC24_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0493319.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTATKYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            22815..23099
                     /locus_tag="VXC24_001204"
     CDS             22815..23099
                     /locus_tag="VXC24_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493320.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23092..23649
                     /locus_tag="VXC24_001205"
     CDS             23092..23649
                     /locus_tag="VXC24_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEV0493321.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT         7637 a         5181 c         4066 g         7187 t
ORIGIN      
        1 attaatttga cttttctgat agagatgttc acatcttatt tcaattcatg atacaatcca
       61 gttcctaaaa ctttgctaga aattaatttg gctttccgaa ttaatttgtt cagattttat
      121 ttcatttcaa tatactgata aatccattca ctagcacagg gcaagaggga gtcgctattg
      181 atttcaacgg tagcaggtac atacagagga ctcctacctc agatatactg caatatcatc
      241 gtgtgcaaaa aacctctgag atttttctca aaggttctga ttttgctaat ttctgttctc
      301 aaccgctgca gtaacaaagg cagtgtagag ttcttctggt cggtttggac ggcttgacag
      361 ttcagggtga tactgacaag ctacaaagaa tttattttca ggaatttcca cgatttctac
      421 caaacgattg tctggagaaa ctcctgaaaa gacaaagcct gctgcctcaa actgctcacg
      481 gaaggcgtta ttaaactcat aacggtgacg gtgacggcgt tgcaccactt cttgattgtg
      541 ataagcagca gcagccttag agccacgttt caacttagac ggataaagtc ccaaacgaag
      601 ggttccaccc atatcctcaa tatcaatctg atcacgcatg atatcaatga tagggtattt
      661 tgtttctggt gcaagctctg cagaattggc accttcaaga cctaaaacgt gacgagcaaa
      721 ctcgatacat gtcaactgca ttcccaagca gactcccaac attggaacat cattttcacg
      781 cgcatagcgg atggcttgga ttttcccttc tgtaccacgt tgaccaaaac cacctggtac
      841 gatgatcccg tctgcatcag acaagagttc tgctacattc tctgctgtca catcattggc
      901 attgacccaa ttgattttaa cttctgcatc attgacatag ccagagtgtt tcaaggcttc
      961 gaccactgag atataggcat cttgcaactc cacatactta ccaacaaggg aaatcttaac
     1021 ttgtttcttg aggttcatga ccttgtccac catggctgac cattctgtca tatccgctgc
     1081 tggtgcgtct aatttcaaat gatcacaaac aatttggtcc atcccttgtg cctgcaagtt
     1141 cagtggaatt tggtaaagat gttcaacatc caacgattcg ataacggctt ctggtgccac
     1201 atcacagaac tgggccagtt tatttttaat tccttgacca gctggctctt ctgtacgaat
     1261 aaccaacata tttggttgga ttcccaagcc acgcaattct ttgacagagt gttgggttgg
     1321 tttggttttc atttcaccag cagccttgag gtaaggaagc aaggttgtat ggatatacat
     1381 gacattatcc gcacccacat ctgccttcat ctgacgaaga gcctctagga atggcaagga
     1441 ctcgatatct cctactgttc caccaacctc tgtgataatg acatcagagt cggtcgttag
     1501 agcggcacgc ttgatttttt ctttcaaagc atctgtgata tgaggaatga cttgaacagt
     1561 tgccccaagg tattctccac ggcgttcttt acgaagaact tcactgtaaa ttttcccagt
     1621 tgtcacgttg gaatatttgt tgagattgat atcgataaaa cgttcatagt gacccaagtc
     1681 caaatctgtc tcagctccgt catctgtcac aaaaacttcc ccgtgctggt aaggactcat
     1741 ggttcccgga tcaatattga tataagggtc aaacttttga atggttactt tgagaccacg
     1801 atttttcaag agacggccta gactcgctgc cacaatccct ttcccaatgg acgataccac
     1861 accaccagtt acaaaaatat atttcgtaga catagattcc tctttctaaa atgctcaagg
     1921 tcttgttaac tacgagggga tatagaaaac aagaccctac taataagaat aatctgggac
     1981 gactgcacca gattcacaac taatactctt cgaaaatctc ttcaaaccgc gtcaacgtcg
     2041 ccttgccgta gatatgtgtt cctgactttg tcagtcttat ctacaacctc aaaacagtgt
     2101 tttgagcagc ctacggctag tttcctagct tgctctttga ttttcattga gtataaaata
     2161 caagaagata acttcttgaa aaaacaaaaa tagctcccta agaactaggg agccccgacc
     2221 tctaaaagag gtgcccaaac aatatgatac ctaaaaatag gataattgtc aatagctaac
     2281 tcttattcct cgctggtttc agcgtcgtca tctgaaaact cgtcgtcgtc ttcgttgaga
     2341 tccacatctt ctcccaagtc atctggagcg atttcgttga tttctgcatc ataagcttcc
     2401 acttcatttt tttcatcatc tggattttca tcatcgtatg aaagagctgg atctgcttcg
     2461 tatgcatctt cgtcttctgg atcatctgca ttgtagtcaa tggcatctga atcaccatcc
     2521 ataaaggcat tgacacgttt tttcttagct tttggtgcta cttcatcgtc gtcattttct
     2581 tcaagagcga tgatttcttc gtcgatttcg tccacaccat accatgaacg aagaccccat
     2641 ttgttgtccc caagtgagat gaagctaccg tcaaagttca actctgtgta gaacaaaggc
     2701 aaagcttcgc ggatatcgct gtttgatgtt ccaaggtagt tttgaatttc gtttacaaga
     2761 tcgctaaaat gcatctcatg atcgcgacca cgaagttcca agatagcacg cgctacctca
     2821 atcatagata gttcactttt ttcttgccca gcaaatactt ctaattccaa agcgtttctc
     2881 ctcatttata ctactatcgc cagagcgaac agactctgac ctcattttat catttactct
     2941 ttattttacg ataattttgc ggaatagtca aaggttaagg gggagaaagt ggcaggatta
     3001 gactaattcc aatataaaac tccttccttt ttctgttgct ccattttcca caaatccaag
     3061 cgacttgaaa cacctcctag aagcatgatt gtaggtgtag atttccttga ctctcaattc
     3121 tttccatcct tttactcgag ccaattcaat caaagcactt agaatctttt ttccaagtcc
     3181 tcgatgttgg taagcggaat tcccaatcac aatggggaga ttatcctgag atagtgtaat
     3241 atccccaatt ggaaaccatt ctcccttctc cttgacttca atccaaaaaa gctcaccatg
     3301 ccgatccaaa taggaataca tggcttccaa ggtcgcttga ctgtaaggaa gcttcacccc
     3361 atctacgagg taaaccaagt tcacatcctg ataccaagca aaagcttcct cacaatgatt
     3421 gaccttataa taaggaacaa aacacaatgc actacctttt caacaaaaga gttgctgctt
     3481 gattaaaacc atcacaccag ttataccatt ttgcttcata cccatcttga gctaggatac
     3541 gatcttctaa atcaaaaaca gagtaaatct ttctttcctc gcaagcttgc gcatagagat
     3601 gatatagttc atcaccacca tctctatccc actcagcaga aatcgtatcc cgacctgcca
     3661 ataaagcctg ataagccctg tgatgcccat ctgtaatcag caaacaatct ccaaaggcaa
     3721 gaatactgat tggatcgact tggtttgttt ctgccgactg gtaaagcatc tgaatatctt
     3781 gcaacttctt ttctgataaa tatagttgag tcggatgaag atctgctata ttgactttca
     3841 tttctttctc ctcaagggaa ttcgatactc acttctgttt gcctttaaat cgccattgga
     3901 agcggagctt gtcatagaag ggaaactcga taaacaggac tcccaagccc acacagagac
     3961 tggcaaagac gtctgatggg taatgaaccc ccagatagac tcttgatacc agcacactga
     4021 ctaggtagag gccaaggacg atttgtacga tttttctcca gactggattt ttaattcgtt
     4081 gactgagaat gacaatcaga gtacctacca tcaaagttac agccagagaa tgtccacttg
     4141 ggaaggaaaa tcccttctct tccaccagat gtaagatagc tggtcgtggg cgctggtaga
     4201 tatttttaaa ggtcacgatt aaaagacctg ccaaagccag atttcccagc atgaagaaac
     4261 tttctatctt ccatcgctta cgataaaaga caaaagctgt aatgacaacc caagtgataa
     4321 tcactgggat atcaatcaga cgtgtgaggg ctcgaaaaag aatagtcaaa taatctggta
     4381 agtctcctcg aatggcagtc tgaatcgatt ggtcaaaatt gaccaacatt tcagggtaaa
     4441 atttgaccat atagccaaga ataacgaaaa gtaaaagggc aaaactgccc ttcattaaaa
     4501 atgtttgttt atctttcata gtgttttaag gttggtttca aaaggacgta caacaaccag
     4561 aatgaaacgg aaaagattac accctcaatc aagttaaaag gtaataccat ggtcattagg
     4621 tagttggaaa gtcccaaaat ttttccaata tcaaagttag caaacttagc gtacaaagga
     4681 acagcataaa catagttgag aaccaacatg gccaaggtta aaccaacagt tccagctaga
     4741 gagcctagta ggaaacgaag ggttgtccgt tcctttttcc aaatcaaagc aaatacgatg
     4801 acaaaaactc ccaaagctac gatattcatc ggcaaaccaa tgtaagtatt cactccttgg
     4861 ctgttaagaa gcaatttcaa tagtgagcga agcaagagca ctcctagagc agcaggcaaa
     4921 tccatgacca ccagacccac aaggactggc aagatactaa attcgatctt gaggaaagat
     4981 gccgctggta aaagcggaaa gtcaaagtac atcagcacaa atgagatggc tgataaaatt
     5041 gcaatggtcg aaagtcgacg tgtgtttgtc ataacaggtt cctccaattt tctataaaat
     5101 cagaagaagt tggaaaggat tcctctatct attctcactt tttatatccc aaaaattccc
     5161 tcttactcta ttaaagaaaa acaaagcaag tggttacaat ccggctataa atctatcaaa
     5221 acagacaaag ctattctttc gtcttctccc atccagacta tactgtcggt tgtggaatct
     5281 caccacatca gcttgcgctc gcggacttct ttaaagagaa ggaaaagatc atttcctagt
     5341 taaagtcacc gccggtcggg aatcacaccc tgccctgaag actcttttat cataacaaaa
     5401 aacgcttgca agcgcaagca ttttgttcat tttcattttc attttttatt tcaatttatc
     5461 cacttcatag gtatggacga gctcaagacc tgcaaagttc tgctggcgaa gagcctcata
     5521 gacaatcatg cagacggtat tagacacatt gagactgcgg acatgttcat cattcatggg
     5581 aatacggaga gccttctcag gatgttctcg cataaaatct tcaggtaagc ccttgtcttc
     5641 acgtccaaag agaaaataat ggtcctcgtc agtcgataaa tccacctcag aatagacttt
     5701 ttctgcgaat ttcgaaatca gatagagttt tcccttcatc tgagatatga aatcttccaa
     5761 actctcgtaa aaataaatct ctagcttatc ccagtaatcc aatccagccc gcttcatctt
     5821 gcggtcatca ataggaaagc ccataggctt gatgatgtgg aggggagaat tggtcgcagc
     5881 gcaagtacgc gcgatattgc ctgtattttg tggaatttga ggttcaaata atacaatgtg
     5941 atttgtcatg acttgcttcc tttcaccatt gcaaaaaaat agccacactg cccggagtca
     6001 agctcagcaa acagcgtggt taaggcatcg ttaacttacc tcacaacagg tttgaagtaa
     6061 atcagcgaaa ctactttctt agtataacac tttcagaatc attgtcaata gaaatgactt
     6121 gattttttca attttttcaa gctatttcca agggttgtaa aatcgtccct gattctgcaa
     6181 gataagtagt aaactaacta ctaaaaacaa ggttgccaag agcaaggtaa tatagtctcc
     6241 ttttttcaag gcctgataac tataccatgt gcgttttttc tctttcccaa agcggcgaag
     6301 ctccatggca gtcgcaatgg tatcaatgcg ttctagcgag ctaaaaatca agggagtaat
     6361 aatgagcaga ttgcctttga ttcgttgcat aagagaagct ttcttggata attccatccc
     6421 acgcgcttcc tgagacatct tgatggtaaa gaattcttcc tgcaaatctg gaatatagcg
     6481 caaggttaga ctgacagaat aggcaatctt gtaaggcaca ccaatttgat ttaaactgga
     6541 agcaaactga ctagggtggg ttgtcatcaa aaagataata gccagaggaa tagtgcaaag
     6601 gtacttaata gccaaattta gcagataaaa gagctcttga ctggtcagag tgtaggcacc
     6661 gattccctgc caaatcacac ttctctctcc gtaaagtcca accccatact cgggagaaaa
     6721 gagatagacc atcaaaacgt ttaaaacggc aaataccgtc gcaaaaacgg ctacaaagga
     6781 aacatcttta aaatggattt ctgacaaata gaggagaaag accgaaaaga tggcaatcag
     6841 aacaagcagt ctggtatcat agctaatcat ggccgccaat gacacgagaa tgaaaaagag
     6901 gagtttccca gcgcctgaca agcgatgaat cacagtatct ctatgctggt aaccgattaa
     6961 tttagcttgc atccttctct cctttctttg taaaatgccg ttaaagcaag tggatccacg
     7021 tcgagtttct tagccaagtt gaagatagaa gtctctttta ggttggcttt tactaacagc
     7081 tcaggattgc tcaacagact agctggatca gtatcagcaa tcaattcccc atccaccatg
     7141 acaagggctc gatctgaata atccagcatc aattgcatat catgggtaat catgacaatg
     7201 gtatgccctt gttgatgcag ttcttcgaga aattccataa tctcagtata gttcttctgg
     7261 tcttgacccg cagtcggttc atctaggagg ataatttcag cgcctaagac caaaattgag
     7321 gcaatagtca cacgtttttt ctgaccaaat gacagggcag aaatgggcca attacggaat
     7381 tcatagagac cacagatttt caaggtttca tagactctcg tttcaatttc ctgctcgtcc
     7441 acacctcgca aacggagtcc cagagccacc tcatcaaaaa tcatattggt tgaaatcatt
     7501 tgattgggat tttgcagcac atagcctact cgttccgccc gctctgcaac agaatctcct
     7561 tttatatcct gtccttccca aagatagcgg ccttcagtct ggataaagct actcaaggcc
     7621 ttggctagag ttgacttccc tgctccattt tttccgacaa tggcaatctt ttcacccttt
     7681 ttaatatcta aatgaagaga ttttaaaatc ggtctatcat cataagaaaa cgacacgtcc
     7741 tctagtctaa agagtgactg caattctggg gtttctttta ccagttccgt ccgcaactga
     7801 acctgacctt ttgagataga caagttatcc agatctgcta attgttcttc cttgactaaa
     7861 tccacaccca attgacggag agtggtgaga taaaggggtt cgcgaattcc attttgggtc
     7921 aacaaatcag tcgccagtaa ctggtcaggg ctcccattaa aaaggatacg accatcgttt
     7981 atcaagacaa tccgatccac agggcaatgc agaacatcct ccaaacggtg ctcgataata
     8041 agggtcgtcg tcccctcctc cttatgaatc tggtcaatca attcgataat atcctgacct
     8101 gacttgggat caagattggc gagtggctca tcaaacaaga gaatcggact ttcatcaatc
     8161 aagacaccag ccagactgac tcgctgcttt tgtccacctg acaaatcctg agggcgctga
     8221 tccagtaaag gaagaaggtc cagcttttca gcccatttat aaacacgacc tttcatctca
     8281 tctagggctg tcacatcatt ttccagagca aacgccaaat cttctgccac agacaagcca
     8341 ataaactgcc catctgtatc ctgcaaaact gtgctaacca gatgagactt atcatagatg
     8401 ctcatatcaa aggctgtttg accctttatc aaaaattctc catatgtctg acccttgtaa
     8461 atattgggaa taatcccatt caaacactga cccaaggtag atttacctga tccagatggt
     8521 ccaacaatta agactttctc tcccttgtaa atggtcaagt ctatcccttg caaggtcggt
     8581 tcttgttgtg tttcataccg gaaagagaaa tccttccact caattatagc ttctttcatc
     8641 ttactctctt cattcgcttc ttagacttct attttatcat aaatcaagcc cttcttgcag
     8701 tctcttctct taaaatctta gcgccaaaaa gattcctatc ctagcttact tgcctaacta
     8761 atctataaac atcgaaaaag actagttgcc cagccttccc catcatttta tactcttcga
     8821 aaatctcttc aaaccacgtc agcttcgcct tgccgtaggt atggttactg acttcgtcag
     8881 tttcatctac aacctcaaaa ccatgttttg agctgacttc gtcagttcta tccacaattt
     8941 caaaacactg ttttgagcaa cctgcggcta acttcctagt ttgctctttg attttcattg
     9001 agtattagtc ctttttcaaa cttcctgcac gagtttgggt tcctgcatag gcaagtaaga
     9061 gaagagttcc tgcaatagct acagatacac cattggcaat tcccgcaaca atcccttgtg
     9121 caaatacttt ttctgccgct tcttgataaa tcacaacatc tccaagtggt gccaagacac
     9181 cccaaacaag ggcatttgca agtagttgaa tgaggttaaa aataagaata tctttccagt
     9241 caaaaacacc attgatcacg cgaacgtact ttctaaaaag tcccacaact aaaccaaaga
     9301 gtccgctagc gataatccaa gtccaccata gaccataacc agcaagagag tccttgattg
     9361 catgaccaat caacccgaca agcaaaccga taatcggtcc aaaaataata gaaagtagcg
     9421 cttgtaccgc atactgaagc tggatgcttg tatttggaac aggggttgga atgttgatca
     9481 tcccgatgac gacaaagagg gcagcgccaa ttccgacagc aacaacttgt ttaattgtaa
     9541 atttaatttc catactattc tcctatttta tccttctatt ttctttattt caatggtcca
     9601 agatgaaccg acacctacat tataggcctt ggcaaaggaa ccttggttga tagccaaacc
     9661 taaacgatag agagagttga tgtaaaggat gggttgccca attctcacat ctgcaaatga
     9721 tttgccatag acaacctgat tttgatagac cagcatatca gcatgataga tggtcacttc
     9781 aaaacgatca ccaaattctg gttccagctt gtaaaattct tcccgtgtga tagaggtcca
     9841 aagcgaaccg aaacgcacat ccagaatatc aatggctccc ttcaccagat gatcttctat
     9901 gatggtcgct acgactggaa gctctacaat ctgttccaca ctgagctctg gccctacttc
     9961 ctcaaaagta atgtgaccac tggccagttt agcaccagta taggcataga catcacgacc
    10021 gtggaaggta taagaatgct ctgtgttttg acgcctattg gccacctcag aaatctcacg
    10081 aatggctaca atgccaacgt gtttcttgat aaaggaaagc gtcccattat ctggcgtgac
    10141 aatgtattga ttttttgcag tcttggcaac tacactctta cgtttcgaac cgacacctgg
    10201 atcgacaacc gatacaaacg tcgttccctc aggccagtaa tccaccgtct gaaagagacg
    10261 atagctcccc tcaaaaatat tataaggcgt gatatcgtgc gtcaagtgat ggatttttaa
    10321 ggttggagac tcttctaaag ccactccaat catagccgat accgcaccat caaccagacc
    10381 aaagtctgat tgtaatacca gtaaattatt attcatttta tctccttgta tatcctttat
    10441 cataccatat ttcagagaaa gtcgctaata gctatttcaa ttggttaggg tatagtttta
    10501 ccttatagcg aattttcact aaaagctctt gttattagct agtaggtgca ttttttcttg
    10561 aaaaagggta tgatagttac atcatgaaaa agtaggtttt attatgaaaa ttatccttgt
    10621 cggaggggga aaagttggtt ttgccctctg tcgctccttg gttgcagaaa agcatgatgt
    10681 tttgctgatt gagcaagacg aagctgttct caatcatatt gtcagtcgct ttgatatcat
    10741 tggtatcctt ggtaacgggg ccgattttgc cattcttgag caagccagcg tccaagattg
    10801 tgatatcttt atcgccctga ctgagcacga tgaagtcaac atgattgcag cagttctagc
    10861 caagaaaatg ggagctaaag aaactatcgt tcgggtgcgg aaccctgaat attctaactc
    10921 ttatttcaag gaaaagaata ttctcggttt ttctcttatc gttaatcctg agctcttggc
    10981 tgcccgtgct atcgcgaata tcattgactt ccccaacgcc ctgtctgtcg aacgctttgc
    11041 tggtggacgc gttagcctca tggaatttgt cgtcaagtcc accagcggtc tttgccaaat
    11101 gcccatttct gattttcgta aaaaatttgg taatgtcatt gtctgtgcga tagagaggga
    11161 tcatcaaatt atcattccaa gcggtgacat gactgtacag gataaagata gaatctttgt
    11221 cactggtaac cgtgtcgata tgatactctt ccataattat tttaaatcac gcgccgtgaa
    11281 gagccttctc atcgttgggg caggtagaat tgcctattat ctacttggta ttctcaaaga
    11341 tagtcgtatc gatacaaaag tcattgaaat caatcctgaa atcgccagct tctttagcga
    11401 gaaattccca aatctctaca tcgttcaagg agatggaacc gcaaaagata tcctgctgga
    11461 agaaagtgct caacactatg atgccgttgc gactctaaca ggagtcgatg aggaaaatct
    11521 gattacatct atgttccttg acagggtagg tgtacagaaa aatattacta aggtcaatcg
    11581 taccagtctc ctcgagatta tcaatgcgcc tgatttttca agtatcatca cacctaaaag
    11641 catcgctgta gatacgatta tgcactttat tcgtggtcga gttaatgccc agtattcaga
    11701 ccttcaagcc atgcaccatc tagccaatgg ccaaattgaa accctgcaat tccatatcaa
    11761 ggaagccaat aaaatgactg ccaaacctct ttctcaactg aaattgaaaa aaggggttct
    11821 tattgcagcc attattcgaa agggcaagac tattttccca actggggagg atatgttgga
    11881 agttggagac aagctcctag taacaacctt gttgccaaac atcaccaaga tttatgactt
    11941 gattgcgagg taagaaatga ataaaagtat gattcgttac ctcctttcaa agttactttt
    12001 gattgaagct gttctcctct tggttcctgt ggctatcgct gtctattacc gtgaatcgag
    12061 ccaagtcttt acagccctct tttcgaccat agggattctc gtattgttag gcggttcagg
    12121 gagtttacag aagccaaaaa atcaacggat ttatgccaag gagggagtct tgatcgttgc
    12181 cctctgttgg atcctttggt ctttctttgg tggtctcccc tttgtctttt ctgggcaaat
    12241 ccccagcctt attgatgcct tttttgagat tagttccggc tttacgacta ctggagcaag
    12301 tattttgaac gacgtttcag ttctcagtcg ttccctcctc ttctggcgaa gttttaccca
    12361 cttgattgga gggatgggag tgcttgtttt tgcacttgct attatggaca atgccaaaaa
    12421 tagccaccta gaggtgatga aggctgaggt tccaggtcct gtttttggca aggttgtatc
    12481 caaactaaaa aacactgccc agattctcta tctcctttat ctagctctct tctccctctt
    12541 tgtcatcatc tattatctag ctggtatgcc tctctacgat agttttgtca ttgctatggg
    12601 gacagcggga actggaggct ttaccgtcta taacgatgga attgcccact atggtagctc
    12661 actgattacc tatctggtta gtataggagt tttggttttt ggggtaaatt tcaatctcta
    12721 ctactacctt atgctccgtc gggttaaggc cttctttgga gatgaagagc ttcgggctta
    12781 cttggtcatc gtgctggttt ctacaggctt gattagcctc aatactctct acctctaccc
    12841 aggattttcc aaaagctttg aaatggcctt cttccaggtt tccaacatca ttacaacaac
    12901 tggttttgga tatggagata ttaccaactg gcccctcttc tcccagttta tcctcctctt
    12961 cctcatgaca atcggtggtt ctgctggatc aactgcaggt ggactcaaga ttattcgagg
    13021 cctcatcctt tcaaaaattg ccaaaaatca aattttgtcc attctatctc cccaccgtgt
    13081 tttgactctc catgtgaata aaacggtgat tgataaggat acccagcata aaattctcaa
    13141 gtactttgtc atctatgcta tgattttgct atcccttatc tttattgtca gcctagatag
    13201 caatgatttt ctgatcgtga ccagcgctgt ctttagctgt ttcaataata tcgggcctat
    13261 tctaggaacc acttctagtt tctcaatctt tagtcctatc tcaaaaattc tcctctcctt
    13321 tgcaatgatt gcaggccgct tggagattta cccaatcctc cttctcttta tgaagagaac
    13381 ttggtctaag agataaaata caaaatccct ctttttacaa ttgtgaaaga gggattttta
    13441 tattaaaaag ggggaacgtt tttaaatcca agcctgtctg taagcaaagt ccttactcaa
    13501 ataaaagatg gaaaaactta ctacacagct tggtaatgct ccaatacaaa ttgtaaggct
    13561 ttacttggat tctttgttaa atgaatatat tccattcctc tggtagcaac tatctgaata
    13621 cctaatcttt ctgcatccac cttcatctct ctataataac tccgaacttg tggagccaga
    13681 ataattaaat cataaacacc cataatatca taatgagctc cgtacgctcc tgaattcgca
    13741 atcactctaa cttctgctaa ttgagcgccc tcgttaattg cattggctaa ttgcgcactt
    13801 gttccagacc ctgcacaaag aaccagtact ttcaactcct tactttttat ttcatctaac
    13861 tcaccaggca ttatttcact tgtctcctcc tctaaaataa tatcatttga gcttgcaaca
    13921 tcttctttca tcagtaactg tctatcatac gctctacaga atggcaaata aatcaatatg
    13981 tcgacaacta aaatcaaaga taaaaataca aaggagatag attgaaaatt cgttccaatt
    14041 aacaatccca agggaccagg aaaggcccaa ggtaactgga tataaaatcc attcattcca
    14101 aagaaatcaa taaagacctt tcctagaaat acattcactg gtggagtcat caaaaaaggt
    14161 acaaaaagat agggattcaa aataactggc ataccaaata gaagaggttc attcaccgca
    14221 aataaaacag gagtaattgt agctttacct accgatttta attgtttaga ccgcataaag
    14281 aaaatcaaaa taaatggtac aacaaaggta gcccccgttc ctccgatagc agcgatataa
    14341 tttccgaaat taggcgttaa agaatgataa ggaaactgcc catttgcaag aagttgagca
    14401 ttctcttcca tattgctcag ttgtaaagct gtaacagcag gtaagacaat agatggtcca
    14461 tgaattccaa caaaccaaag caaagcgcac ataaaccaaa tcaacatcat agcaggatat
    14521 gattctgccc ccttaaaaat aggagtcaat agttgttgaa atacttgggc aaaaggaaca
    14581 tctaaactaa accgagatac aatatctaac aaaccactaa taagtaaaac aaaagaaaaa
    14641 ggaaaaatat ctctaaaagc ttgtgatata gccccaggaa cttccttagg taaatgaata
    14701 gtaatgtctc gcttaataca gaatcggtaa acatttacag taataaaggc actgacaaac
    14761 gaagttatca atccttgaga tcctaaatag tttgtcgaca aacttgtaga tcccgtcttc
    14821 tcatcaacta caagcgttac agttaatacc agataactac atatggctgc caacattaca
    14881 gaagtatcat ttattacctt tccaggaggc atttttctat taacatttcc agccaatgac
    14941 tttgcaactg tccctgaaac aataacaccc aaaactccca tggttagcat atacactttc
    15001 ctcatccagg caatagctgg actcggtaac tctactccga aatttttagg aatcataata
    15061 ataatcatca aaaagcttga aaacataatt aaaggcatag tagcaatgaa tccatcttta
    15121 atagccatca tataattatt agtagaaatt ttttcaaatt tcccttgttg cttttcaatg
    15181 gcagcgacta gcttatccat aaaactcctc ctataaaaaa ttcaacctca tatttaaaac
    15241 atattaaaca tcattcaaat cgctaacctt aattccgttt tagccctttt acccaaagag
    15301 cacttttctt aatatatcgc ttctgtgtct cataatcaac aaagaaaaga ccatatcgct
    15361 tattgtagcc attcgcccaa gaaaattgat cttgcaaaga ccatataaaa tatccttgaa
    15421 tattgactcc cctatctcga gcctctaaaa ctttgtgtaa atgttgctca atataacgga
    15481 ttctcttact gtcatcaata atatcattct cgccctctgg cttaacctct ttaagggctg
    15541 taccattttc agttaaataa atgacaggat gttgaggata ttcttctttg atacgaagta
    15601 acatatcaaa taagccttga ggataaatat tccaatccca atctgttgtc ggaataccag
    15661 gcttttttac aaattcacct agagcattta atttaaaaga ggactgtcct tttattcctg
    15721 ttgaattaaa ttcttgtcta ttttcacctt tgtattcacg aataaattct gaacgataat
    15781 aattcatccc aaacatcgta ttaagaggtg cagctctttt cataatttct aaatcaccat
    15841 cttcaataat aaagctagaa ttattagctt ccaatatttg atttaagtga aaaagcgtgt
    15901 catcactgta gtagcccaaa aaagttccat ctaatagaaa tttattatta taaacatcat
    15961 accgtttagc tgccaaaata ttttcttttt gcccatcaat aggatagcct ggctttaaag
    16021 catgaataca acctaccttt ccctcaatcc ctaattgatg aaattcgagg actgcaagag
    16081 catgcgccaa caacatatta tgattcgctt gaattgcttc agataattga aaatgatgat
    16141 tcggaggaaa ctgacctcct atatattgac ctgcagcaag agacatcagt tcattgattg
    16201 taaaccaatg cttgacttct gtaaattctt ggaaacaaaa gcgagcatat cgtatgaaac
    16261 gatcaatatt ctctctattc aaccaatccc ctgtttctaa cattttctga ggcgaatcaa
    16321 aatgatgtaa agaaacaaac ggaatcacat tatgttttaa gcaggactga aagactctat
    16381 ggtaatactg aacagccaat atattcggct ccccatctat atcaggaaat atgcgaaccc
    16441 aagaaataga taaacgcaaa gcctgcaaac catgttctgc cgccaaggct atatcttctt
    16501 cgtaacgata ataaaaatca ctagctggat ctggtaagaa cggactattt tcttgcaaat
    16561 aaacatccca catatttatt cctttgccat ctaccctagt tgcaccctct acttgataag
    16621 cagcggtagc agctcctaat aaaaactcct tcggtaaggc tttaacctgt aaattttcca
    16681 tgactaatcc tcattgcaaa ccaatatgtt cttcaatctt tcgaattcgt tcatattcat
    16741 caataaaaaa ctttacctga tcatacaata gcatcgttgt catcaaagta tcttgaccat
    16801 gaatcatgat aaaactcact tcaaaattat ctccagatgc ctcctccgct aataaattag
    16861 tctgttctcg atgggcagac actattgagt cgtttgcaga ctcaaccaat tctcttgcct
    16921 gttcaaaata tccatctctc gcaaacgcca aagcatccat caaatctgac cttgcatctc
    16981 ctgcgtaagc gacaattgta aaaccaagca tatttatttc ttcttttgat ttcatctttc
    17041 ttcctcctca atcttgatac atcttttaca catcattatt aaaatgactt cgctacgata
    17101 caaatagaaa gttgacccta aatatcttaa aaatccttaa atttcataat atttaggatc
    17161 aatcttctct gaatacctta gttcattttc tatacttata atttataagt ggaaaccagc
    17221 gtaatttttt gctacttcaa ttacacgata aacatccaaa ttagattgga atagcaattc
    17281 gtgaccacgg atataattca aaacatttct ccattcatct tgagcttgcc ttgtttttcc
    17341 agttgcttga agatataaag ccttcgccat cttaacaaca tattcacgat gataactgag
    17401 ctgtttccat tcatcctttt gactatttaa taacttagaa atattttcct caataattgg
    17461 taaaaaatta tcagctagat tgtaagctat ataataatga ttcgctaaaa catcattttg
    17521 acggctgcca attgcattaa aataatcaca tgaggaataa ctagataatt tttctaaata
    17581 ttcaacaaca gactgccaat ttgacccata caaagcagaa aagtattctt caatcaattc
    17641 ttcataactt cttgtcttct tccagagcat ttgccccata acataattag gaaaattatg
    17701 agggaatccg gcacgtaatt cttgacacga aatgtacccg ttcaaatgta ggtttgaaag
    17761 ataagataca tctttgtaaa tagtttgact aattttcata tagcctaaat cgccataatg
    17821 agcacgccct aaaggatagt catatacgaa actatctcct ttaaatgttt tttgccactc
    17881 aaaaagataa gataaatttt cttcaagaga attcggaagt ataattttat tacgcagata
    17941 aggtttaggc gtaggtatgg aattgtcaaa atctacatct gcataactca tttcaaatgt
    18001 tcttgtaatc ggtgcaaaca tcatggtaaa gcgttcagga ttatctaatt tttctttctg
    18061 aggcgcccat aacaactcat ggtaaagtag gaaacaaatc tttgtatcta atccctcact
    18121 cgttaaagcc ctatccaatt gattgagaat acgaatatac tgatccgaaa ccaattcttg
    18181 tctacagttt tcgcattcac aaatattatt acgagcatcc gacaaccata catgtaagta
    18241 gttaacatca ggtcttttct tggcataatc cttaataatt tctaccatct tatcagctac
    18301 atctggattt gaaaaatcca ggctggttaa aatcggagcc gtattaaaca attctcgttt
    18361 cccgtttatt tcagcgacat agggtttctt ctcctctgaa atactaagac ctgattccca
    18421 gccaaatttt gaagagtaac ctaaaacctc acctgtccat ccatgaccaa cacgatgatg
    18481 aataagacct cttttttgca attctttatc caacctatca ctcaattctt gtactaattc
    18541 atttgagaat ttttctttat ttaggtatgg attaaactca tgttcatacc aacgtttcaa
    18601 aaaagaatag ggattttcaa actgaatgaa aaaactgttc atcccaatct taggtagcca
    18661 atcaatgaaa tctagtatat tttcaaatga atctgctccc tctatacata ctcccctatg
    18721 atagtaactt gctgtttcat ctatagatag ctctttatct aaaaaatctt caaatcttaa
    18781 ctctggaata aagtcatgtc cgcgccctgg tctagtatac acaacaccaa attcatgaaa
    18841 cattcggtaa attccaataa gtaaacctac aattgtattg gactcaattc tccccttacc
    18901 tttgtttaat gagatgaaaa tatggtcttt tccatcctct tcattgacta atcctacaaa
    18961 aatatccgct tccttctcct cgacaagttc tatatcggta ttaaatacct gattcatata
    19021 gtatcttaat tcctctaagg caaagctaga ataagtattt ttctgttgat caaatactct
    19081 gataaccatc ttatttccct ccaacagtag ctttttcttt ttcaagattg cgtttatctg
    19141 caattttgaa gaatggataa taaattgcta cagaaaccaa aatcaaaaca acttgtaata
    19201 gagctcctcg ccaactagcc cctgtcgcaa ggaagcctcc tatgataggt ggcattgtcc
    19261 acggaaggat tacacctgtt gtatagggta ctaagcctac agccattgat acataggtaa
    19321 tcaaggcatt gattgtagga gtagcaataa acggaatcag cataatagga tttaaaaccg
    19381 ttggaaacgt aaatagaata gctgtattga tattaaagat agacggtata atagctagct
    19441 tacctaatgt tttattagca cgactcttac taaataggaa gagacaaatc gcaagaccaa
    19501 tagtcgctcc accgccacca ataaatacaa ataaatcttt aaacggtaat gtaataatgt
    19561 gttgtagggt ttgtcctgca gccacagctt cttggttttc tgtagtaaat tgtaaccaaa
    19621 ctgggtctac aaaagcattt aaaacttgtc ccccattaac tccacagaac caaaagaatg
    19681 agtttacaat aacacataaa atcatacctg gaagtgttcc tgcaattaac ttaagcggcg
    19741 ttccaacaat tgcacctaaa agtccgttga gacctcctgc aactcctgct gcttccagac
    19801 cttttaagac caaagcccac aaaacaaaag tagtaaaacc aggtaaaaga gctgaaaatg
    19861 atttactgac cacatctggg acaccatttg gcatttttat cgtaattccg cgttggataa
    19921 aaatacgata aatctccgct gtaaccaatc caatggtaat cgccataaac aaagaagacg
    19981 cattcaggct agaaaatggt attgcacctc caaataactg cttgacctgc tccccatttt
    20041 tatcataaac catacttgaa aaacgagggg ccatcaatac aaaactggat aaggctatga
    20101 tccctgcaga cggaccatct gtaccatatc cttccgacaa cctgtaggca ataccgaaac
    20161 aagcgaccaa ggagataatc gctactgttg actgattcat agttgtcaag atacttagca
    20221 atccaacact attcagccaa tttgtaaaag cctcttgagg ccaactgatt agaataagaa
    20281 ataaagagcc gactaaaatc aaaggcattg ccatcataaa tccttcacga atagctttca
    20341 aatgccgttg attgccaact ttttcaccaa acggagcgac tttcgtttct aaaaacgtta
    20401 aaatattgtt catcactgga actccttttt ttatttttta taaattaaat ataccactaa
    20461 cagaaagcgt tgtcaatata ttttttactg tttttacaat atttttttct ttgtatagaa
    20521 taataatttt aattgatttt ttcttatgtt taatataaaa taaaccaaag gaggaaacaa
    20581 atgattacaa aacaatcagc ctttttacaa aatagagcca ctatactgga atttctatat
    20641 cgaaatccag caacatcccg tacagatatt gttaatgaaa caggacttac tccagcaaca
    20701 acgactaaca tcataaaaga gctaagcgaa caatccctca tatacgaaac tggtgatgaa
    20761 tttagcgagt tttccggatc tggaagacgt agaaaaacta tttctattac agataatatc
    20821 ccatctgttg ttggaggtat tgaaataaac gtcttaggta tctttctcag tctatgtgac
    20881 ttacaaggga aaactctttt cgagacagaa attttgaatg aagattatcc tatttcagaa
    20941 atcaattcca ccattaccaa tatgataaaa acagctacaa agtatgtccc tttggagaca
    21001 aaattacttg gatttggctt atcaatacct ggacattata acaaagactc cggaagcatc
    21061 attacaaaca accccatatg ggaatcattt aatttattaa atgtaattaa aaaattcgat
    21121 ttccctttta ttgtaaaaaa taatatcgat tgtatggcta taggacaata cctttttaac
    21181 ccacacaata cccccgataa ctttattttc ctacacgctg gattaggtat ttacacttcc
    21241 tttttcacaa aagaaaaaat aggagcctct aaaaatcctt atatcggaga aattggacac
    21301 accattgtcg aattaaatgg gcaatattgt gaatgcggaa aaaaaggttg tttacaaaca
    21361 tatatttcgg atgcttggtt aatcaaacat gcccaattat tatttaaaaa ttctcaacta
    21421 actgtactaa aaagccttgt aaagactgaa aaagacattc atttagatac ccttttaaca
    21481 gcttacaact taggcgactc tgctttacgc caacaaattg ataaaggagt caatttattg
    21541 gccacttcta ttgcaaatct tctcctcatc aatcctgctg ataaaatcta tatcaacagt
    21601 caattgctta attatcaacc tttcactcat gaagtcaggg ataaaatcca agatcagctc
    21661 cacttcgttc cctttactcg taatatagaa attgaaattt taccttacaa caaacatcgt
    21721 ggaagtatag gagcttgtgc attagctatc gttgcttttt tcatagagca tagcaatgta
    21781 ttacaagata ttatttcacc ttaatatatt agaaatctat agacctgttt aaatcaacta
    21841 taacctgtag taaatatctc gtatttagac aatatgaaaa caagacgact tccatatagg
    21901 aaaccgcctt ctcgctatgc tgcatgaaac tgtaaaaata gatgaaagtg atagcggtag
    21961 tcaaatcaag aggcatcata actctaaaaa gtcacaatat ataagttcat cctcagaaaa
    22021 atatcattct aattattgaa atgcctacat gaaaagaaac gttaaatgct cataaaacaa
    22081 ggaatacagg tatcaaaact gtgacaaaac aagtccctaa atttactaaa gacactactc
    22141 aactttacac ctgtaaatgg ttgttgtata ataaagttac aaagatgtac gaccacactg
    22201 ttgtaaatca tagtgttcgc gaatatatta ctgatagcat ttctacaaat acaagtaaag
    22261 ggattggatg agattcaaac gaaatatgtc agtgttttgg cattcctagc cttcatatca
    22321 tttaaagaat tgtatagata aaatttttcc caatacagac actcgtaaca actgcttcat
    22381 ttttctacca acatatttag gaacaggata agatacaaga ggatcaatcc ataaatcagt
    22441 tctataccaa tctaagacaa ataagctaaa aaaacgattg ataataagca aatagattcc
    22501 aaattttctc tatctgctca ttttaataaa caatactagt gtaactatcc ttccagtcag
    22561 aagcttgtca aatcacaccg aaaattcttc taaaatttat ctcgttaggc aatcaagcaa
    22621 aaactcaacg atagtacaaa cattatcata caggattgac ttcctaaatt atatacttta
    22681 gtaaggtttt tggataagaa aaaaggttca ttttacattt ctaaacactc ttttctaata
    22741 cgagataatt aaaaaaacta catttttaaa tataaactac aataaaataa actaaatgcc
    22801 ataggagaaa gacaatggat tggtacgatt atatgataca ggcatccaaa caatcacaat
    22861 tcaacgcaag ccattggttt cgctatttgc gaaaagttat ttttgaagac tattcttatt
    22921 taacaaacca agatatagaa aagttgctag actccaaaga actaacccat tttcaaaaaa
    22981 ttagcttgaa gtatgccttt caagagcata ctccaactca taaatatgtg atttcattaa
    23041 ataaacctgc taagttaacc aatgttcaaa aattgatgga gaaatacaag catggataaa
    23101 atgaaaccgg tcttccaagc actaaataag gaattaattc aggaaaatct gactttaaca
    23161 attatctgtg tcggtggtta tgtcttagaa tatcatggtt tgcgtgccac acaagatgtt
    23221 gatgcttttt atgaccaaaa tcagaaaatc aatgaaatta ttgctcgtgt aggaaaacag
    23281 tttaatctta acacccacga agagttatgg ctcaacaatc atgttgcaaa tatgaacaaa
    23341 caacctccct taagtttatg cgaatccttg tactcatttg agaatctgac cgttttagta
    23401 gtccctattg agtatgtgtt aggaatgaag atgatgagta tcagagagca ggatttgaaa
    23461 gatattggtg caattattaa atacaaaaac tttcattcac cattcgatac ctttaaatat
    23521 ttaaaagaca tgggatttga tactattgac ctctctgttc tattagaagg ttttagttat
    23581 gcttatggta tggattggtt agaaaaattt tttaaagaaa atcaagataa acttcgcgaa
    23641 ttttattaac agtatcaaac aagatgattg tcaattagcc agtcgtcttg tttttatgat
    23701 gaaatgaaat aaaatcggaa caaatcactt agagaattcc agtcaatttc tagcactgtt
    23761 tgagacgttt cagcggacta tagcaaaatg aaataagaat aggacaaatc gatcaggaca
    23821 gtcaaatcga tttctaagaa tgttttagaa gtaaaggtgt actattctac tttcaatcta
    23881 ttatatttca gattcggtcc actattcctt cccaaaaaca ttgcatattg cgccgaagga
    23941 attgctcata ctatcccaag cacaaaaccc tcagtcgttt gaccgagggt tcctttttat
    24001 tattcaagaa cttgaggctc tataatattt gtagtgggta aatcccctat ggatattatg
    24061 gagcctattt t
//
LOCUS       DAVLBN010000030        23652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLBN010000030 DAVLBN010000000
VERSION     DAVLBN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.030"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(92..241)
                     /locus_tag="VXC24_001206"
                     /pseudo
     CDS             complement(92..241)
                     /locus_tag="VXC24_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(395..2026)
                     /gene="rlmD"
                     /locus_tag="VXC24_001207"
     CDS             complement(395..2026)
                     /gene="rlmD"
                     /locus_tag="VXC24_001207"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0493322.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2100..3074)
                     /locus_tag="VXC24_001208"
     CDS             complement(2100..3074)
                     /locus_tag="VXC24_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0493323.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3148..3762)
                     /gene="pmp23"
                     /locus_tag="VXC24_001209"
     CDS             complement(3148..3762)
                     /gene="pmp23"
                     /locus_tag="VXC24_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0493324.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3762..4736)
                     /locus_tag="VXC24_001210"
     CDS             complement(3762..4736)
                     /locus_tag="VXC24_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0493325.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4744..6000)
                     /locus_tag="VXC24_001211"
     CDS             complement(4744..6000)
                     /locus_tag="VXC24_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0493326.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6062..6493)
                     /locus_tag="VXC24_001212"
     CDS             complement(6062..6493)
                     /locus_tag="VXC24_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493327.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6495..7097)
                     /locus_tag="VXC24_001213"
     CDS             complement(6495..7097)
                     /locus_tag="VXC24_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0493328.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7081..7920)
                     /gene="prmC"
                     /locus_tag="VXC24_001214"
     CDS             complement(7081..7920)
                     /gene="prmC"
                     /locus_tag="VXC24_001214"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0493329.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(7920..8999)
                     /gene="prfA"
                     /locus_tag="VXC24_001215"
     CDS             complement(7920..8999)
                     /gene="prfA"
                     /locus_tag="VXC24_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0493330.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(9009..9488)
                     /locus_tag="VXC24_001216"
     CDS             complement(9009..9488)
                     /locus_tag="VXC24_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493331.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9478..10077)
                     /locus_tag="VXC24_001217"
     CDS             complement(9478..10077)
                     /locus_tag="VXC24_001217"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0493332.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10201..10383
                     /locus_tag="VXC24_001218"
     CDS             10201..10383
                     /locus_tag="VXC24_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0493333.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10520..11893
                     /gene="mnmE"
                     /locus_tag="VXC24_001219"
     CDS             10520..11893
                     /gene="mnmE"
                     /locus_tag="VXC24_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0493334.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11940..12875)
                     /gene="dapA"
                     /locus_tag="VXC24_001220"
     CDS             complement(11940..12875)
                     /gene="dapA"
                     /locus_tag="VXC24_001220"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0493335.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12931..14007)
                     /locus_tag="VXC24_001221"
     CDS             complement(12931..14007)
                     /locus_tag="VXC24_001221"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0493336.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14349..14421)
                     /locus_tag="VXC24_001222"
     tRNA            complement(14349..14421)
                     /locus_tag="VXC24_001222"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14386..14388),aa:Thr,seq:ggt)
     gene            complement(14521..15030)
                     /locus_tag="VXC24_001223"
     CDS             complement(14521..15030)
                     /locus_tag="VXC24_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0493337.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15028..15124)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15153..15584
                     /locus_tag="VXC24_001224"
     CDS             15153..15584
                     /locus_tag="VXC24_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0493338.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            15667..16044
                     /gene="mscL"
                     /locus_tag="VXC24_001225"
     CDS             15667..16044
                     /gene="mscL"
                     /locus_tag="VXC24_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0493339.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16086..17180)
                     /gene="hemH"
                     /locus_tag="VXC24_001226"
     CDS             complement(16086..17180)
                     /gene="hemH"
                     /locus_tag="VXC24_001226"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0493340.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17258..18133)
                     /gene="srtG2"
                     /locus_tag="VXC24_001227"
     CDS             complement(17258..18133)
                     /gene="srtG2"
                     /locus_tag="VXC24_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HEV0493341.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(18211..19209)
                     /gene="srtG1"
                     /locus_tag="VXC24_001228"
     CDS             complement(18211..19209)
                     /gene="srtG1"
                     /locus_tag="VXC24_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEV0493342.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19227..20423)
                     /gene="pitB"
                     /locus_tag="VXC24_001229"
     CDS             complement(19227..20423)
                     /gene="pitB"
                     /locus_tag="VXC24_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HEV0493343.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20468..21019)
                     /gene="sipA"
                     /locus_tag="VXC24_001230"
     CDS             complement(20468..21019)
                     /gene="sipA"
                     /locus_tag="VXC24_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEV0493344.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21019..22971)
                     /locus_tag="VXC24_001231"
     CDS             complement(21019..22971)
                     /locus_tag="VXC24_001231"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEV0493345.1"
                     /translation="MDAGIGTGTNINAGLTEAQRLLQSARAGAKKVVILLSDGEANMY
                     YESNSGRTIYNYYSNPNVGRMIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYI
                     GSNDSITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVL
                     SKYVQLLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLED
                     DAKYVLKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRT
                     KIKDYSEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSY
                     RKVTSPVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQ
                     LPSLTVKKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQET
                     ALSYLPRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVIKKVTG
                     AFANLLQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKIL
                     DLPLNARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTL
                     VLGVVLPLGGIFFIILLGHLVVNRRK"
     gene            complement(23101..23604)
                     /locus_tag="VXC24_001232"
     CDS             complement(23101..23604)
                     /locus_tag="VXC24_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HEV0493346.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
BASE COUNT         6793 a         4976 c         4428 g         7455 t
ORIGIN      
        1 ttattttttg agttttaaac tttggtagaa gtcttgaact ccttatattt acataactat
       61 ttgcctctat aactgttatg acacgaaacc aacaagcaag ttcaagcacc tccatatctt
      121 tattcaaatg aggactaaga tattcacaaa ctttatcata aacctcttta tcttttttca
      181 taaaaggggc atacaactta gcaaatttat cctaaaattt tttgttgcct ttatcaatca
      241 tttcaacgct cctttaaata taaaaatgat cctatcaatc tttatattga gcctattttc
      301 taattgatac cttgcaagaa aggaataata gctgttccta taccaagtag gaatgtaata
      361 aatgcagaaa gtcatatact gtcattcttt tctattaaat cattttgaag tgtctcaaag
      421 catccatgat ggcttcttct ttttcaggtg tacactgtgg aataatttgt ttatcctttt
      481 tagacttgtt gtaatgttct cgtaattcta ttccacattt cttttttatc tgtgcaatat
      541 ataatgtcga aacttttaat tcaaatttat tccaaacata ttctttgatt tgagcatatg
      601 ttgctttgct ctccgcactt gtcaaatcca tctcatccag ctcaatttca acacttatgt
      661 gcttatcgac atcaagtttg gacaaaagtg ctaccgtctc gacgtgatgc gtttgaggaa
      721 atagatccac cggctggact ttcttcaatt catatcccaa ttcttggtag agtttgatat
      781 cacgcgccat ggttgcgaca ttgcaggaga tataggcgat gcgatcggct cctgtttggg
      841 cgcttgcttt gataaagctt tctgtcaagc ccttgcgtgg aggatcaacc aagataacgg
      901 ttggttgaat cccatcttta agccaattct tcatagcatt ttcagctgtg tcacagacat
      961 agtgggcgtt tgaaatattg ttcagctgag catttttttt actattctca accgcttctg
     1021 gaatcagttc aacaccgtag acttctttga catgcttggc gactgataaa ccaatggttc
     1081 caataccaga ataagcatca ataaccacgt catctttttt taactctgca aagtcaatgg
     1141 ctgtttgata gagtttctcc gccatttcag tattgacttg gtaaaaggct gggccagcga
     1201 tttggaagtc atttcccaac atctggtccg taatatagtc ttgaccataa agagtgcgcc
     1261 actccttacc aaaaatcgca ttggtattct ggtcgttgat attttgcatg acagacacaa
     1321 tctctgggaa ctgcttgata acttgttcaa tcaattggtc aacacgaaaa acttttggac
     1381 gagttgtcac caaaacgacc atgatttgtc ctgaatagtg accacgacgc accacaagat
     1441 tccgaatcaa tccagactgt tccttttcgt cataaggttt taaatcaaaa cgacggagca
     1501 ggtctcgaag agctactacg acttggtcaa tgacaggatc ctggataaag aaatcttcaa
     1561 ggggcatgag gttatgcgaa ttcttacgga aaaatcctgt ttccaagaca ccattcactc
     1621 gacgaacggg cacctgcgcc ttattgcgat acttgactgg atgttccata ccaagcgttt
     1681 cagcaacttc tacatctgca attccagcaa tcttgtagag actgtccttg acttgcttgg
     1741 ttttaaactt gagctgttct ggataagaaa ggtgtcctaa atccgcgatt cctgaacgca
     1801 ggtaagccaa atctagatct tgattacggt gtggtgactg gacaaggtat ttttcaactt
     1861 ttccaaagcc aatcttttta ttgaccttga ggacacgcat gaaaattttt tcactcggta
     1921 aagcattctc tacaaaaaag accaaaccat ctaccttggc aactcctgcc ccttcatggg
     1981 tcaaatcaac aatttcaact tctacaatat catttttctt taacattctt ttctctttct
     2041 attggccgac aaaaaagacg gcaacgttac ggttaccatc cattatacca tgaaatttct
     2101 taagaaccaa aactcttgaa gaagttgaca agggcttgcc agagggagct taagaagtta
     2161 ccaccgtcct ctagcgcctt atccgcatca aagttaaggt tgatattttt aaaactgtcg
     2221 ccagcttgtg atacgatgct ttgtttaagg tcatttaggg ttttagtgaa atctgcattg
     2281 ctgaggatat cactctttga gagattcaag gcaaaattga tgatgatatt gatctggttt
     2341 cctgttatga cctgatcaag tttgtaattt tttaaggtat cttcaacaat cttgcggata
     2401 tcttcttctg tcagatttcc cttgctttct ttagctttgg cgagtcctga cttgatatca
     2461 gctagggcaa cgtttaattt attagcatca tagcctgatt tgtccttgtt ttcagcattg
     2521 atatctgaca aagcctttag ctcttcttga gccaaatctt tattggcttg cggcaccttg
     2581 gctccattag cttctagcga atagtagatc ccagccaaag cactctcacc tgtaactgga
     2641 atgggtgctg ctacagtgat tttggcgtgt tccacaccca aagttacggc tgcatttcgg
     2701 tacatatcct gagttacctt agtgatgttt tcaggtgttt caatcttgac ctcaagtggc
     2761 gatttgtcac ctagcttttg aatcttggct gatgaataca actgtaagct agagtcattg
     2821 gccacattca tgattttaga ataaacatca ggtgtcatgg tcttgagttc tttggtatct
     2881 gttgaggcat tgtagcccag ttttttaaga gtttgatttt tttggtcttc agatagggaa
     2941 gaacctagga catattcagg ttggacatag gtttcatcga taactttttg aacatctgtt
     3001 gctgcatgga cgctattcat agctgttact gcccacaaga tcgcagcgct agtcagaaag
     3061 agtttctttc tcatagggaa tttcctcctt tacttcttta gagtaatata tctatcttaa
     3121 agaaaactta taacaaaaac acctggtcta gccagatgtt gaaaagagag tgaaacattt
     3181 gatgatgtaa aggttaagtc gtacctgtct agaataataa tagtttcctc catttacata
     3241 gagttcagca ccgtgaaaaa tggaaatggg gtgaatataa ctataagtct ttccagtcgt
     3301 attaccaagc aagggggcaa cagtctcacg agagtactgt ttggctagag ccaaggtatt
     3361 ttccttgcca ttttgggcga taaaatcgat ataggcaggt ccaaaattat aggcttgaac
     3421 agctgtccag atatctacac ccttcttctg cgccagatag agattgcctg tcagagtttg
     3481 aatgccttgc cgaatgctag aggcattatc attgatggtg ttggtggaac cacttgcaga
     3541 ctcactagac tgcataacat cgccttcttt tccttttgtt tcagtataaa tcatagcaag
     3601 cacaagctct tcgtttgctg gggtgtcttt ttcactcaat atttctcgca ccatgggttg
     3661 ataggtcatg acttgtttga catcttgatg aacgcggtaa gctttatagc cagcaaaaag
     3721 gaagactgct agtacaagca ctcttcgaat tcgtttaaac attatttact ttggatatcc
     3781 tcgatatttt tgattaagat agagtaggtt ccattttcgt tttggataaa ctcaacagac
     3841 tcggcgtctt gatagacgtt attgggaacg atgagctcaa ttccatttga taaggagagt
     3901 ttttggtttt caaatttctt taattggcga ctggcatcaa tttcatcaaa ttgaacaggt
     3961 tctggtacgg cttctttgac ttggtcaata aagctcaaac gagccgtcag attgttgtca
     4021 aaaaggtcat tagccaattt ctcaggtgac aattcattgc tttcttctag gttgttgaaa
     4081 atagctgatt tgaccttgga ttgaaattga aaatcatctg tgttaaaaga ttcagcaatt
     4141 ctctgggctg ttttttccag ttccttgata gattttttag gagaaatctt aggagcgaca
     4201 gcaagaagat tatctgaaaa atagttcaaa aaagtcccgt tgtacttgat tcgtttttca
     4261 atcaggtgat acttgcgact ctgaagattg accaccaagg cctcgtcagc acccgttcca
     4321 aatccaggca ggttattctg agtcagcttg attggattat caacttctcc tccgaggtgg
     4381 gtcaaggtct cccgcagggc aattcgcaag aaagcgaaat gttctacacc ttctttagaa
     4441 aattgaacaa aaatcaagtc attggtcttg agattttcag aaatgctaaa ctcctctttc
     4501 cagagattag ccagcgttac tgatgtctcc aacaaatcgt ctgtaatatg attgaagaag
     4561 ggattttctt cttcgaaaat cccagtcttg gcttcatctg aatacacatg ttcaattttt
     4621 ttacgtaggt attcttcgat ttttggagta atattgagaa acttatctgc taagaacagc
     4681 tcggtatcat ccggactgaa ctggtgaata atggctttct taatataaat gtccataaaa
     4741 gttttattcc tcgtataatg ggaaggcatc tgtcaattct ttgactgcac ttctcacttc
     4801 ttctaataca gcctcatttt ctgaattctt aagggtttta atgatgagtt cagccacttt
     4861 gcgactttct tcttcaccaa atccacgtgc agtaatggct gctgctccga tacgaatccc
     4921 acttgtcttg aatggtgaca agctttcgta agggattgag tttttattta aggtaatatt
     4981 gacttcatcc aacaagtttt gagcaacttt gccgttttct acaactttag tcacatcaac
     5041 aaggaagaga tggttttcag ttccacctga aataatacgg aaatcagggt cttgcaagaa
     5101 gacatctgcc atagccttgc tgttcttaat tacattggca gcatattcct tgaaggctgg
     5161 atccaaaact tctttgaagg aaactgcctt agccgccaca acatgctcta aaggaccgcc
     5221 ctgaatacct gggaaaatag ctgaattgat ttttttagca agttcttcgt cattggtcaa
     5281 aatcaaacca ccacgaggac cacgaagggt tttgtgggtc gttgttgttg tgatatgagc
     5341 gtatggaact gggcttggat gaaggccagc cgcaaccaaa ccagcgatat gggccatgtc
     5401 caccatgagc ttcgcaccga cagcatctgc gatttcacgg aattttgaaa aatcgataat
     5461 ttgagaatat gctgaagcac cagctacaat cagttttggt tttacttctt gggcttgttt
     5521 caagatagca tcaaagtcta agagttccgt ttcaggatca acactataag aaacaaagtt
     5581 gtaggtttga ccagagaagc taacaggagc cccatgagtc aaatgaccac ctgatgccaa
     5641 atccattccc ataaccgtat cacctggctc aatcaaggac atgtaagccg cacagttagc
     5701 ttggcttcct gaatgtggtt ggacattggc aaatttagca ccgaaaattt cttttgcgcg
     5761 ttcaatagca agagtctcta caacgtctac tacatcagtt ccaccataat aacggcgtcc
     5821 tgggtaaccc tcggcatatt tatttgtcaa gatagaccct tgagctgcca taacagcctt
     5881 ggaaactacg ttttccgaag caattaactc gatattattt tgttggcgtt cttcttcttt
     5941 ggcaatagca ttccagagat cagcatcata tgctttaaaa tcatctttgt caaaaatcat
     6001 aggtcttctc ctttattgtg tgactagtcc attagtttga ttttacaata agaaaatcaa
     6061 actaaaagat gcgaataaac cgtttctgca ttttatcaca agtatagcca actttttcat
     6121 aaaatgcatg agcacccaga cgatgattgg cagaatttaa gcggataaac ccataaccac
     6181 atcttttggc ttcttgttcc aacccttgta gtaaactttt accgatacct tcaccttgcg
     6241 cttgaggtga aactgctaaa gctaagatat taaatcctgc tttggaatag agtgattcgt
     6301 aaacttcagc gtggacatat ccaagtaaga catgattagc tgcatcctca tagccaagta
     6361 ggaaatgatg ggaatcctga gacagtctag ctagttggct agccgtttcc tctagactaa
     6421 aagtataacc caaagcctct tggttgatgt cacatatcgc tttcacatct gtttcttgca
     6481 aatctcttag catttcaagc ctcctcaaaa gaaatctctg gcaaccgagc aagaatatct
     6541 tctcgtttaa ttgcgccttg gcgtaagatt ttcaccttgt ctccagacaa atccacaata
     6601 gttgaatcct gtccagttag aaaagcatcg tcttccagac ccagaacctc ttggtcaaaa
     6661 tccttcagaa tttgttcaaa ggttacacca cttgcctgac ctgagatatt ggcagacggc
     6721 ccaatcaagg gacctgtctc tcgaattaaa tccagtgtga tagggtgact gggcatccga
     6781 aatccaatag ttgcaaggtc agaatttacc caatagggaa ctcggtcatt ggcttcgaga
     6841 ataatggtca agggacctgg caaaaaggtc tctacaagtt tttgtagata agttggctga
     6901 ttcttagaaa agtgcaagat atcctcgaaa gaggcgatat tgagattgag tgccttatct
     6961 ctaggacgac gtttgagttg gtaaacatgg tcaactgctt tttcatctaa ggccttggca
     7021 aaaagaccat aaacagtctc tgtaggtaga acgacagctc caccattttc caactcttgt
     7081 ctaatcctgt ctatcatcaa ccacgaccat cctattttga ccaaattggt ccttgagtgt
     7141 tcgaactctt ttttcaggaa gatgtttcct aaaaagttcg ggaacacttt gaccttgctt
     7201 gtatccaatt tcaaggtaaa tcttaccacc atctttgaga tagtcttttg catcttccgc
     7261 aattctacag taaatagcta ggccatcctc gtctgcaaag agagctagat gaggctccga
     7321 atgcaaaaca ttcaagccta cctctgactc atcttcacga gagatatagg gtggattgga
     7381 tacaattata tcatattttt cagaaatttc tgcaaaacaa tcagattttt taaaaaatat
     7441 attaagattt tgattgctag cattctctga tgcaagctct aaggcctctt gagaaacatc
     7501 tgctgctgtc actgaccaat ctggtctatt ttttgctaga gcgagagcaa tagctccact
     7561 acctgttcca atatccagaa ctgaaagatt cgtctcaaga ttttcagtta gaataagctc
     7621 cactaactcc tctgtttctg gacgaggaat caaaacccgt tcatccacct ttaaatgcat
     7681 tccataaaaa tctgcctgtc caatgatgta ctgagctggc ttgtgagctg ctagttgctg
     7741 gtaaatatct tctacaaatt gtttttcttc ctctgttgtc acctcctgct ggagggcaaa
     7801 aataaagtct gtaaaagata gatttttcag actacgatag acaaaagaga ggctttccgc
     7861 ttcctctcct tgtcttatca actcttcttc aaaatttgaa aataattgag ctaatttcat
     7921 tatttgttta attcttttag tttttgtgtt tggtcataaa gcaccaaggc atccacaact
     7981 tcgtccaatt taccagacaa aatcgtatct agtttttgga gggtcaagcc gatacggtgg
     8041 tctgtgacac ggttttgtgg gaagttataa gttcggatcc gttctgaacg gtcaccagta
     8101 ccgattgtcg acttacgctc agcgtcttgt tcatcctgag caatctgagc aaagtggtca
     8161 gcgacgcgtg cacggataat cttcatagcc ttctcgcggt tcttctgctg ggtacgttct
     8221 tcctgcatct caaccttgat attggttggc aagtgaacga tacgaacggc agtcgcaacc
     8281 ttattgacgt tctgtccacc agcaccagag gcgtgataga tgtcgacacg aaggtctttt
     8341 ggatcaatgt cgtattcaac ctcttcaact tctggcataa caagaactgt cgctgtcgaa
     8401 gtatgaacac ggccttggct ttctgtcaca ggaacacgtt gcacacggtg ggcacctgat
     8461 tcatacttaa gcttagagta tacagactga cctgaaacca tagcaaccac ttctttaaaa
     8521 ccaccgacac cattcataga ggcttccatg acttcaaagc gccaaccttg ggcttccgca
     8581 tacttttggt acatagttag caaatctcca gcgaaaagtg ccgcttcgtc tccaccagct
     8641 gctccacgga tttcaaggat gatattcttg tcatcgtttg gatcctttgg aaggagcaaa
     8701 attttcagtt tttcttcata ttcttctttt tcagccttgg catctttgag ttcttgcttg
     8761 gccatttctt ccaagtccgc atctccgcct gattccttaa tcatctcttc ggcatcgacg
     8821 atattttgaa ggacttgttt atactcacgg taggctatta cggtgtcacg attggaagct
     8881 tcttcttttg aaagctccat aaaacgcttg gtgtctgaaa cgacatcagg gtcactcagc
     8941 aattctccta gttcttcata acggtcttct acagcttgta gttgatcata gatgttcatt
     9001 ttttctcctt atttctcaat tgttaaatca tagattgcta ctacttcatt ctcggatatt
     9061 tccccagttt ctttaaatcc ataactgaga taacaaaatc ttgcctgttc attttctggt
     9121 tcataagaca accaaagttt attgcttaaa cctgctggcg ctgttcgaac atagtctagt
     9181 actttatcca taattggttt aaaatatcct tgattttgaa aattcttatc aatcataaaa
     9241 caaaatagta aataatttcc actactaatt acgatctttt tatcataagc tatcatcaca
     9301 aaacctataa ttacatcatt atcataaact gccaatggag ctacaaaatc tccattttta
     9361 gtgtagacgt atgcttcagc taaactaatt gcgttggttg caatgaattg tttttgatat
     9421 tccttgacat ccaaatttaa aacatcaaaa taattttcca ttgtaacatc tcttagttca
     9481 attgtcatag ttttgctcct tgttagaggt tatcattggc gcaaaataat gtttacggca
     9541 aaccgagata taggtttcat taccaccaat ctggatctgt tctccatcgt aaacgggcag
     9601 tccatcctgt gttcgcaaca ccatggtcgc ctttttcttg caatactgac agatggtctt
     9661 gatttcgtca atcttgtctg ctaaaagcaa gagatatttg gaaccttcga acaattcatt
     9721 gcgaaagtca tttttcaaac caaaagccat gatgggtatg tctaactcgt ccacaacacg
     9781 agctaggtcg taaacatggt ggcgtttaag aaactgggct tcatcgacca aaacacagta
     9841 aggtttttct ggtaggtctc ggatatagcc aaagatatcc gttgtttcct caatcgcaag
     9901 ggcagggcgt ttcatgccaa ttcgactcga cacatagcca acaccgtcac gcgtatccag
     9961 agccgaggtc ataatgacaa caccttttcc ttgctcctca tagttatagg ccaccttgag
    10021 aatctcgatt gtctttccag agttcatggt cccataacga taatacaact gtgccatgtt
    10081 tcttgcttca cgtccatttc taaatttttg ctacattcta gtatatcata attttcttaa
    10141 gctttaaacg gcaaaatgtg gtaaaataga agaaatcaaa aactagtgga ggaagctatt
    10201 atgccatttg tacgcatcga tttatttgaa ggacgcacgc tcgagcaaaa gaaagctctt
    10261 gctaaggaag taacggaagc ggttgttcgc aacactggag cacctcaatc tgctgtccat
    10321 gtcatcatca acgacatgcc agaaggaact tacttcccac aaggggaaat gcgtaccaaa
    10381 taagctagct taagcagaat tgcttaggct ttttcaatct ccaagtagca ttcattgaag
    10441 aaatatccta aatttgttac aatttgaaaa gaaacttgga gaatttccaa gaaaatagct
    10501 attaattaaa ggaaacatta tgattacacg tgaatttgat accatcgctg ctatctctac
    10561 tccactaggt gaaggggcta ttggtattgt ccgcctgagc ggaacagaca gttttgctat
    10621 tgcgcaaaag atttttaaag gaaaagactt gaacaaggtt gccagccaca ctctcaacta
    10681 cggtcacatt attgatcctc tgactggtaa agtcatggac gaggttatgg ttggggctat
    10741 gaagtctcca aagaccttca ctcgtgagga tattatcgag attaacaccc acggtggtat
    10801 tgcggtgacc aatgagattc tccagctagc tatccgtgaa ggagctcggt tggcagaacc
    10861 tggtgaattt accaaacgtg cctttttaaa cggtcgcgta gatttgacac aggccgaggc
    10921 ggtgatggat atcatccgcg ccaagacaga caaggccatg aacatcgcgg tcaaacaact
    10981 tgatggttcc ctttctgatc ttatcaataa tatccgtcaa gaaatcctta acacacttgc
    11041 ccaagttgag gtcaatatcg actatcctga gtatgacgat gttgaggaag ccactactgc
    11101 tgttgtccga gagaagacaa tggagtttga gcaattacta accaagctcc ttaggacagc
    11161 acgtcgtggt aaaatccttc gtgaaggaat ttcaacggct atcattggac gtcccaacgt
    11221 tgggaaatca agccttctca acaacctctt gcgtgaggac aaggctatcg taaccgatat
    11281 cgctgggaca acacgagatg tcatcgaaga gtacgtcaac atcaatggtg tacctctcaa
    11341 attgattgat acagctggta ttcgtgaaac ggatgatata gtggaacaaa tcggtgttga
    11401 gcgttcgaaa aaagccctca aggaagccaa cttggttcta ctagtgctaa atgccagtga
    11461 accactgact gcgcaagaca gacaacttct tgaaattagc caagatacca atcgcattat
    11521 tctacttaat aaaaccgacc tgccagaaac gattgaaact tcgaaactac ctgaagacgt
    11581 tatccgtatt tcagtcctta aaaaccaaaa catcgacaag attgaagagc gaatcaacaa
    11641 cctcttcttt gaaaatgctg gcttgattga gcaagatgct acttacttgt caaacgcccg
    11701 tcacatttcc ctgattgaaa aagcagttga aagcctacaa gccgttaatc aaggtcttga
    11761 gctggggatg ccagttgatt tgcttcaagt tgacttgact cgtacttggg aaatcctcgg
    11821 agaaatcact ggggatgctg ctccagatga actcatcacc caactcttta gccaattctg
    11881 tttaggaaaa taagaaaaat ccatgatcct tcattcggtc atggatttta ttgtctttat
    11941 tagtaatctg gtcttaagac ccctgttaca gttgccttag ttgcttcgta gtcgccatct
    12001 acgacaacct tgataatgcg tttggcatct tcttctggtg ctggaacaag aggtagacga
    12061 gtgggtccag cttcaaatcc catatagtta agaattgcct taactggagc aggacttgga
    12121 taagagaaga gagcattaac cttaggaatg aatttacgct gaattgctgc ggctttcttc
    12181 atatcgcttt ctgcaatggc agtaaacatc tcgtgcattt catccccatt tgtatgagag
    12241 gcaacagaaa taaccccatc cgccccaagg ttcatggcat ggaaagcatc tccatcctca
    12301 cctgtataaa tcaagaactc ttcaggcttg tgctcaatca agtaagccat attagccaag
    12361 ctagtacatt ctttgacacc gataatattt ggatggtcag ccaagcgaag catggtttct
    12421 ggagtcaatt cgacaactac acgccctgga atgttataga taataattgg taggtcagaa
    12481 gcatctgcaa tagtcttaaa gtgctgatac atcccttctt gagaaggttt gttgtagtaa
    12541 ggaacaatag caagcccagc tgcgaaacca ccaaattccg ctacttcttt gacaaactca
    12601 atagagtcac gcgtatcatt agtacctaca cccgcaatca aaggaacgcg tccattgaca
    12661 accttttgta cagccgcaaa caactccaac tcctcatcgt gggtcaaagt tggactctca
    12721 gcagtcgttc ctgcgagaag aattccatcc gtatgatggg ccaataaatg ctcaatcaag
    12781 gctggaatag catcaaagtt aatagaacca tcctcatgaa agggggtaat aaaggctgta
    12841 atgattttac attcttttaa atcttgataa gacatgaaaa cacctctcta tttcaaagaa
    12901 ggagttcatc tgaactccta aacgatatga ctattttaat tcaaatttca attcggctgt
    12961 tggacgaacc aatccacgtt catgaagagt ttcagcaatc tgaactgagt tccaagcagc
    13021 acctttgaga aggttatctg aaacaaccca catgtgaatt cctttttctg catccaagtc
    13081 tttacggata cgaccaacaa aggtatcacg cgaaccaact gcattgatag cttgaggata
    13141 gatttgatga gctacatcat cttcaagaac agcacctggg aaggctgcga tagctgcttt
    13201 tacttcttcg attggagcca cttcttttgt ttcgatataa acagactcag agtgagctga
    13261 caagactgga atacgcacac atgttgcaga tactgcaatg ctatcatctt ccataatttt
    13321 cttagtttcc ttggtcatct tcatctcttc gtacgtgtaa tcattatcag tgaaaacatc
    13381 aatttgtgga agagcgttaa aggcgatagg ataatgtttc ttgtcaccac ctgaaggcaa
    13441 aatttccgca tgcaaatcac atggtttcac accatcattc aagacttcac gaagttcacg
    13501 ttgtgtctca agaattgctc ccataccagc acctgaaacg gcttgataag ttgaaacaat
    13561 gatacggtcc aagccccatt tttggcgaac cggctcaaga gccaccatca tttggattgt
    13621 tgaacaatta gggcaggcaa tgattccgtt gtgggcatca agtgcatgag cattgacctc
    13681 tggaacaacc aaaggaacat ctggattttg acggaaataa gatgtattat ccactactac
    13741 cacgccagct tttactgcgt atggtgcata cttagctgat gtagaactac ctgctgaaaa
    13801 gagagcaata tcaactcctt caaaagctgt ttcagtcgtt tcttcaattg taatatcttg
    13861 atctttaaat ttcaatgact tacctgctga acgtgcagaa gcaaggtaac ggattttatc
    13921 gattggaagt gttgattctt ccaacatttt tatcatctga gcaccgacag cacctgtcgc
    13981 gccgactaca gcaactgtat atcccataaa taacctcttt cggaattttc taaaaatttc
    14041 tataatagaa gtattatact actttttcca tgaattgcaa agctttttca tcattttttg
    14101 gaaaataaaa atcccagtcg ctagactagg gactaagagg catcttcatg tgatgagcag
    14161 gttcacacaa ctcatcaagg tccgctcctg cgttatgacc tccttatgct caatagtagt
    14221 ccgaagacta cctatcgact catcgcatat tctatattac tagagatact tgattttgtc
    14281 aataagaaat tttttcgatc gagtataaca aaaaactctc gtattcaaga gtttccctat
    14341 acatatcatg ctaattgccg ggatcgaacc ggcgacctca tccttaccat ggatgcgctc
    14401 tgccaactga gctaaatcag cttacttaag aagtatacta tattcagaaa aacttgtcaa
    14461 gtttccttag aaattttcca taggaaaaag ccaggtaaga actacctagc ttatcttctt
    14521 ctatttactt aaatcaattc gacgaccaat tttaccaata ataatcgccc caataatcaa
    14581 tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg aagaatggta attctgctac
    14641 aatatttaac tctgcagcga tagtaaacat ggaaattgaa aagaggattg aaaagaagaa
    14701 atgatctttt tgaatcaatc cgttaaagag gtaatccttg ctatattttg caaaaagcca
    14761 aacacctaaa ctgaggaata ctaaggttga accaccacca acaaagacat ctagcagtcc
    14821 gaagctaaag aaattagcaa tcatacaacc gatggtaact ccgatgatgt acttaggatt
    14881 gtaaaaagcc ataaagttca tcatttctga aatacgaaac tgataagcac catagctgat
    14941 ggcatttagg ggcggtgtga cagtcaaaac gacgtagata gcagcgacga ttgcaatatc
    15001 tgcaacatca cgaatagtta attttttcat cttttctcct ttggcggttg cccgcgtgta
    15061 atatgcttgg tgaaagaagc taagcaccaa gggttgcttt attcaaccct actagtatag
    15121 cacaatagcc tgctttatgc tatacttaac acatgaaaat tcctattcaa aaatttttta
    15181 acaatgaaat cttagcctat ctcttttttg gccttgcgac aactctagtt tcgattctct
    15241 cacgactagt catttatcaa ctaagtcatc aggaactcct ggctactgcc ctagcaaata
    15301 ttatcggtat cctatttgcc tttatcacaa atgatacgat tgtatttaag caaaaaaaga
    15361 aaaatagact tatccgttta gtgaaatttt ctcttgctcg cctttctact tttctgttag
    15421 acttgttttt aacttttctc tttgtaaccc aatttcctca cattataggg caattcgtaa
    15481 ctgaaaacat tgataagata aatgctattg aaacaataat tgcacaaata ttcattatta
    15541 tcatcaatta tatattgagc aaggcctata tttttagaaa ataatgctcc atttatgagc
    15601 cttttaattg ccttctataa tgaatttagg atacaatgaa acacgaaaca ttgaaaggaa
    15661 aacagtatgt taaaaaatct aaaatcgttc ttgcttcgag gaaatgttat tgaccttgct
    15721 gtcggtgttg taattgcctc tgcttttggt gctatcgtta cttcacttgt aaacgacatt
    15781 atcactcctc ttattttaaa tcccgctttg aaagctgcta aagttgaacg tatcgctcaa
    15841 ctttcttggc atggagtcgg ctatggtaac ttcttaagtg ctattatcaa ttttatcttt
    15901 gtgggtaccg ccctcttctt tattatcaag ggcattgaaa aagcacagaa actgactggc
    15961 ataaagaaag aaaaaactgc cgaaaaaaaa ccaaccgaat tggaagtcct tcaagaaata
    16021 aaagctctcc ttgagaaaaa ataatcgatt aaaaggatct agcgcaaagc taaatccttt
    16081 tttctttact ctttgggtaa cttgcctgct ttttcaagca tttttttgat cagataaggc
    16141 atcttaacat tctcccgccc ttttttctca atcagttttt tcacaaattc tggcatttgt
    16201 aaatcttcag attcagctaa aatgtttttc gtctcgtctg aaggaactaa ctcatcaaag
    16261 gtctcttctt ctgggagaaa ttccttaaac tcttgatttt cattgactct aactgtattg
    16321 accaaagcat caatcaaacg agaatctgta tttggcattg gtggacgatg gtagtttacc
    16381 ccaaattcct ggcataagtc ataacattct acatcattgt caaacaagac ctcaatatgc
    16441 tcactgatga aactaatagg tacaaaaata taatggtctg gatgttctgt ctgttctctg
    16501 agatactcca aaacatctgg tttaatccat ggaataccaa tatcactctc actctgccaa
    16561 gtgttggtat attgttctga actcaagccc agtttttcag cgactagctt gctattttcg
    16621 aaaatttggt ctatataagg atcaccaaag tccaaggcaa aaatgggcac actatgggct
    16681 gaaaagatga ctttaaagct gtcttgcttt acttcttctt ttaaaatctt agcaatttca
    16741 tctgcccaat agtttaagag cacttcttcc tgataccagt ccttaatgac caaaaattga
    16801 atttgtttgc tttctaaaaa tttttcatag cccatgacag agtagaaaga ataatggggc
    16861 tccaaaatca agcagataca ttcttcaaca ccatcagttt ccatctgctt gatcacgtct
    16921 ggaataaagg gacgagaaaa tttgttggca aagtagatac cgtactcctc ccctaaacgt
    16981 tctttgacta aattgacctc ctcacgtgta atccgctgca aaggcgtccc accgatacga
    17041 atatagttgt catagagagt ctggatttcg tggtcttggg gtctaactcc acgacgaatg
    17101 tttgtaaaga attctgctac tccttcaaaa ctaatctcct ctggagatcc aaaggtcatc
    17161 attaatatgg cttttttcat gttatcatcc ttatgatatt attttctcta tccattctat
    17221 catgaaagaa aaaaatagta aacgtttcct acgtctacta tttcttttgc tcttttgttt
    17281 ttttatctcg tcttataatt aggatgataa ggacaagaag taagaggacg ataataagga
    17341 gtagaaaggc tagaatgtaa atccaatgac tgggaattcc gtgatcgaaa taccgtgttc
    17401 ctactgcttc cccactttca tcctgtgcta ctttcaccgg tgcatccgtt attttagcta
    17461 aaaggatatg tcgtccatta gttatgttaa ggaaacaggt gcttaataaa acaatcttgt
    17521 ccgttgaggt caaggaaaca tctcgcttgt acttggcttt acttagcaga tattgatagt
    17581 aagcctggtg ttcctcatcc ttggaactca aggttcgata aatctccgtg tcataggcat
    17641 ccacttctaa aatcccaaaa atttcaagac cacgttctcg accattgtag tagatagaac
    17701 cgtagcgatg ctggtcgaag aattccttat cagcaaattt cttaatctca ccgaacatag
    17761 cccctgaagc catagagtgt ccgtagatga tcgtattaaa atcagtaaag ttgggattaa
    17821 agcgatagtc gagaaaaatt gatcccatta tcgtataatc gccaaaggca ttgcggtcaa
    17881 ggtatttgac attatcctga ctttgtagaa gcggatagtc taccttggtc ccatcaaggc
    17941 taatccaacc gcaaacatct ttgttcaagt gctgtagggt ttcaaaacct gtgctcgaag
    18001 catccttttc aataggatta tagtgatcat agtcacttgc ttctactact ctctgccaac
    18061 taaaaagagc tacaaaaaca cagaagaata ccagaaatac gtttttaaat cgcgctcttt
    18121 tttgaaccgt catcagcact cctttctatg cgagatttct taaaaggaaa ggaggcggga
    18181 caaaaccgcc tcttttctat tcacccttag tcagtaaaag ggtctgcttc ttgcattttt
    18241 tttactctct cttctacgac gtaggatcaa gtagaggaca aggagtaaga aaatcaagag
    18301 caagaacaat acaaacaaga taaggtacca aatccatagt gggattgatg agaggaaacg
    18361 tccaagagac gagtcatcaa agacactgta tggaaatggt tttgattttt ttgtatggaa
    18421 agtattttta gggacggtgt ctgtaatctt tgcgactacg atatgacgac cattggtcac
    18481 atcgagaaaa caggtactga gtaggatgat acgatcactc ggtgagagtg agatatcccg
    18541 cttgtgcatg gcgactgaga gcaggtggtc tagataggcc tgctggcggt cctcaccctg
    18601 tattcctgga tcatagatgt taaagtcata ggcatcaacc tccaacatct caaagatctc
    18661 gagccctttt tccacaccat tgtagtatat actaccgtaa cgatgctggt caaaaaattc
    18721 ctgatcagca aacttagcca catcaccaaa catgacccca ttttctacgt ggtgcccgta
    18781 gataatggta ttaaagtctt cgaacttagg attatttcgt gcatcgagaa agatagcgcc
    18841 tgtcgctgca aactcacctt tggagtcctt gttgagatac ttttcattgt ccttggcttg
    18901 gactaaggga tagtcgatat tggtgccata gacattgatc caaccgagga cttcgggatt
    18961 gagttcttgg agtttgctga agcctgaaaa actggccagc tcatcctgtt gcgtcgtgac
    19021 aggtcgataa gcttcgtact cacttgacga agctaaggag tagacttggt tggaatccca
    19081 aagggcgtag aaaccaaaga gaaagatcaa agctgcaaaa atgagcagca agtgattgat
    19141 caccccatcc acagcaagaa cgagacgcct agacagactc ttttttggtt tctcacgctt
    19201 ggttttcatc atctgccccc agccgtttag gcttctctac gttttttaga caagacaaca
    19261 aatccagcca aaccaagacc aatcatcaaa atgaatggaa ggttatcaat caagagacca
    19321 gtaggagtaa cgtcgtcgat tttgttagta actttgttgt cgtttttctt ttcacctatg
    19381 aggatatctg ttaatgtaaa atctacattt ttttgtcctt gagatgtttg ttctgcacca
    19441 tttgtagtat aaattgatga atctgtataa cctgctactc cagtttcagt tactgtatat
    19501 ttagaacctg ctggtagttg ttcaactgta aatgtttcac catctttaag agtaaaattg
    19561 tactcaactg tatctgctgg ggtcactact gccaacacct ctgacttaga tccatgtttt
    19621 actataatat tcgtaacagg ggtttctgct gttttatttg tacttggaag ttgaatcttg
    19681 atatggaatt ggaaatctct tgttttatcc cctgaagctc catcaacttt tttagtaatt
    19741 gttaatgctt tcgcattggg gtctacttga ctcggatcat caggattagg ctccttactt
    19801 gcgtctttgg tatatgtgtt atcaaataaa ttataaacgc cttgttcact tggttctact
    19861 ttaggggcgt tagatttatt attttcctta aagtatactg atgaaatata gacaccacca
    19921 tttactttat tcttaacaat aacgtgcatt tcatatgtac gtttgtcgta tctcatggca
    19981 tcaattgttt taccattttt ggtaatcgcc tgccatccag tttttgcttc cgctacatca
    20041 taaacgtatt caccagcatg gccataagca actcccgaaa aaatgtcttc tgttgctttt
    20101 tgaatcttat cagcagttgg gtgatcattt ttattgtatt ctacatttct atctggaatt
    20161 gcaactccgg tttgatatgg cgcaccgtta gaagattgtc ctgttttttc tgtaaactta
    20221 aatgtaaatg tcgctgttgg tgttgttatt ccctctgcaa tattcaacgt tttattaatc
    20281 ttcacaacag cattattttc accatttgct ttggttattg ctgaattatc atccgcaaaa
    20341 gtcgggacac ctctgaatac ggacaaagcg gttatagctg caatgcttgc agtgaatagc
    20401 tttttaaaga atgttttttt catgattatt tcttttgttt ttttattttc ttttttcatt
    20461 atgatcatca aaagcctcgt cttctaatga ctgttacaac tttgccttga gtatcctgta
    20521 tagggatggt tccaaaagca cgactgtcta cagccgttgt tcgattgtcc ccgaggacaa
    20581 aaagttgtcc tgctgggact ttcatcggga aggttgcccc ttccttatag agcagcgttt
    20641 ctttgtagat atcttgctct tgttgaggag aaccgttgat gatgagacca ttttcgttta
    20701 tatcgattgt acttccttcg gttgctatga cacgcgccac tctttcctta cctttataac
    20761 tatagactag caaatcacca atcgaatagc gtttatccaa cctataatag acgaccaagt
    20821 cgccatcttt taaggcgggc ttcatgccat cgtcattgta tcttaataat ccaaagacga
    20881 aaaagtaaag gatggctagt acaaatccaa ccatcagaag tttactgact aagtaaagga
    20941 tatctcccca gacactcggc ggagacttat cccgattgac ttgtgttact ggtttcttat
    21001 gtttcttttt aagcagcatc acttcctcct attcaccaca aggtgaccaa gtaagatgat
    21061 aaagaagatc cctcctagag gaagaacgac tccaagcacg agagtgctac tcaagaagtc
    21121 aattcccgtt tcaggtacgc tgtttttatt attcgtgact gtcgcagact tatttgcatc
    21181 aagagttcct tcttttttat cataggacac ctgataccca cgagacgaac ttgcttcttc
    21241 ttcgatacta taacgagcat ttagaggaag gtcgagaatc ttgatggttt tatctttctt
    21301 tagatcaact gtcgccttac cattggtgaa ttgtagcgtt gttttttgat tatttactat
    21361 tgcactatac gatccattca atggtttatt ttgcgcatcc tttacgttaa tggtaatctt
    21421 aaaggattgc agaagattag caaaagcacc tgtaactttt tttatgactg aaagtgtcgg
    21481 aagtctgtgg ttggtgacga ttgtttgaac atcctctgac aaagtcccct cttgtttttc
    21541 ataggtgaca tgatatcccg ttctagagtt ctctacttct tccaccttat agtgggtatc
    21601 acgaggcaga taactgaggg cagtttcctg actatttttg agagaaatct gtgctttccc
    21661 gttagtcact gttgtattcc caaacttgcc gttaatcggc ttgccatcct tatctgaaag
    21721 ggtaacatta attgtgaaag atttattagg tgattgttca ccttctagga ttttctttac
    21781 ggtgagactt ggaagctgtc ggtaaataac tttgaaggat ggtttctctt tcgtacctgt
    21841 cttttgaact tcgactgtgt atcccggagc gtctggtgct ttcagttcgt agtcatatcc
    21901 cttagctacc tttgcaaaac tagtattttc agtaaaacta ttcgtttgaa ctggactagt
    21961 gacctttcga taggaatcct ttatacttcc atctttcttt tggtttaagt ttaattcgac
    22021 actaggtgga cgatttgctg atggatttga ttttccatcc acacctttcc actcaatctc
    22081 tacaggaacc gtcaatggat ctgacggctt gaaagtgggc ttctcagaat agtcttttat
    22141 tttggtacgt gaggtcccaa taccatagga ataggcaact tttgccccct tgttggagta
    22201 gagtttagta gcatcggctt cttcggcatc atcactagta agtgtcttat cacccgcaat
    22261 cgcatcaaat gcctcttggc tagaggtgac agtaaacttg agaacgtact tggcgtcatc
    22321 ctctaaagtg taactcggat taaacttggc tgttacttcc actaatccct gttcgttctt
    22381 cttagtttca atcgtaactt gattgtcatt cagttcttgc tcgttaccat ccttgatttt
    22441 gacgacacga aggtgtgaag catcaccagg taacagctgc acgtacttgg acaagacatc
    22501 tgatatagtt acatggtgta cgcctagagg tagaatttta tctgtgattt ctttgaattt
    22561 ttgttgcaag tcattttcat tattggcaga aaatatttcg ttggggattc cagaattata
    22621 accactgata tatcctttaa gagatgtgat actatcgttt gaacctatat atctgaattt
    22681 gattgaataa aagccatcta tttttggagc tattaaacta gatatattca gcattcctct
    22741 ctctaaacca gaggtaaacc aatatggagt atcaatcata cgtcccacat ttggattaga
    22801 ataatagtta tatattgttc tcccactatt agactcgtaa tacatattag cttcgccatc
    22861 tgacagcaga ataactactt tttttgcccc agcccttgca ctttgcaaca atctttgagc
    22921 ttcagttaac ccagcattta tatttgtccc agtgccaatg cccgcgtcca taccataaga
    22981 acgactagag tcagcaattg ttaacgaact aacaatattt tttgagctat tagaatccgt
    23041 gctccaagat actaaagttt tagcatcatc atatgaagag atatttgaat accaaccagc
    23101 tcaatttggc caagttccat attgataact cagataatat tcattataat aacggtcatt
    23161 atactgatta tcaatctttc cggcaaaacc aactatagac agacggtttt gggaattaga
    23221 aagaattgta tcaatgagcc cctgacgacc attcacacct ttcagtgtat gttttagtgc
    23281 ttcaatccta ctaatgtatc gtctactaga gtaagaccac acatctcgct cttccatact
    23341 ccctgaaaga tcggcaacca agactacatc caagggttct gactgggtct ccgttcccag
    23401 tttagatgtg atatccagtg acaactcata ctggtctttt tgccctgata tcggagtaat
    23461 cgttttgtgc agagttgtct gaggttcagt tattgaatct gcacgtaaag aattaattgg
    23521 tgcacacaaa aaaagaatag cgagaaagat aactaaacta ctggtaaaat attgaatctt
    23581 cttaaaatca tattgaacgt tcatgctatc tcccttgcta gaatatgttt taatctgata
    23641 ctatataaat ct
//
LOCUS       DAVLBN010000031        23142 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLBN010000031 DAVLBN010000000
VERSION     DAVLBN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.031"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..210
                     /locus_tag="VXC24_001233"
     CDS             19..210
                     /locus_tag="VXC24_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493347.1"
                     /translation="MYFRLFSNFDDFLEKNYLKTIWQVSKETPFSEMDFNIFKNISEK
                     IIFERGSKMLNDLKSNYKK"
     gene            348..1001
                     /locus_tag="VXC24_001234"
     CDS             348..1001
                     /locus_tag="VXC24_001234"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0493348.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            1011..1475
                     /locus_tag="VXC24_001235"
     CDS             1011..1475
                     /locus_tag="VXC24_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0493349.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1488..2756
                     /locus_tag="VXC24_001236"
     CDS             1488..2756
                     /locus_tag="VXC24_001236"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0493350.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2770..3030
                     /locus_tag="VXC24_001237"
     CDS             2770..3030
                     /locus_tag="VXC24_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493351.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            3041..4402
                     /gene="pdrM"
                     /locus_tag="VXC24_001238"
     CDS             3041..4402
                     /gene="pdrM"
                     /locus_tag="VXC24_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0493352.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4556..5524
                     /locus_tag="VXC24_001239"
     CDS             4556..5524
                     /locus_tag="VXC24_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0493353.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5540..6532
                     /locus_tag="VXC24_001240"
     CDS             5540..6532
                     /locus_tag="VXC24_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0493354.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6750..7793
                     /locus_tag="VXC24_001241"
     CDS             6750..7793
                     /locus_tag="VXC24_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0493355.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7857..9542
                     /gene="lpdA"
                     /locus_tag="VXC24_001242"
     CDS             7857..9542
                     /gene="lpdA"
                     /locus_tag="VXC24_001242"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0493356.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9606..10595
                     /locus_tag="VXC24_001243"
     CDS             9606..10595
                     /locus_tag="VXC24_001243"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0493357.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10668..11738)
                     /gene="xerS"
                     /locus_tag="VXC24_001244"
     CDS             complement(10668..11738)
                     /gene="xerS"
                     /locus_tag="VXC24_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0493358.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12246..13796)
                     /locus_tag="VXC24_001245"
     CDS             complement(12246..13796)
                     /locus_tag="VXC24_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0493359.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13812..14591)
                     /locus_tag="VXC24_001246"
     CDS             complement(13812..14591)
                     /locus_tag="VXC24_001246"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0493360.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(14578..15429)
                     /gene="ylqF"
                     /locus_tag="VXC24_001247"
     CDS             complement(14578..15429)
                     /gene="ylqF"
                     /locus_tag="VXC24_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0493361.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15675..20924)
                     /locus_tag="VXC24_001248"
     CDS             complement(15675..20924)
                     /locus_tag="VXC24_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0493362.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(20968..>23142)
                     /locus_tag="VXC24_001249"
     CDS             complement(20968..>23142)
                     /locus_tag="VXC24_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV0493363.1"
                     /translation="KSVQYSSADVRKVLDISGNIKLTELYLGEQFEKTKANIEDSLSK
                     LLTADAAIVENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYNFNYGETNAKDLIMYH
                     LDFFGKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKV
                     FLPTISNNEWFKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSM
                     VLPLLTLPEEKTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRD
                     HYDYWYKILDNDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPA
                     GNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLG
                     PEFYAKGLLQAPDHPYDPTITINSVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHN
                     MFDVIYMLEYLEGKAVANLETNQKYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEV
                     NKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRI
                     AFELLAAKGYKEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYK
                     TWTQFKKDMYKEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDA
                     QDDVAKFYPETNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK"
BASE COUNT         6835 a         4472 c         4418 g         7417 t
ORIGIN      
        1 ttacaccaag agaatgcatt gtattttcga ttgttttcta attttgacga ctttttagaa
       61 aaaaattatt taaagactat atggcaagtt tctaaagaaa ctcctttttc tgaaatggat
      121 tttaatatat ttaaaaatat ttcagaaaag ataatcttcg aaagaggtag taaaatgctt
      181 aatgatttaa aaagtaatta taaaaaatag ccagtcttta taaactgtat tcacgtattc
      241 aaatcgtata tatagtcgat ttattaaatc tttagataaa ctgtaaaaag tggtttccat
      301 agccactttt tgctataata gaggcagtaa aaatgaagga gtcggctatg gaacactcgt
      361 cttggcatgc tttgattaag gcgcaattac ctgagggtta tttcgggaaa atcaatcagt
      421 ttatggagca ggtctattct caggggatta tttatccacc caaggaaaag gtttttcagg
      481 ctctcttgac aacactgctt gaagaagtta aggtggtaat tctagggcaa gacccctatc
      541 acggaccagg tcaagcgcag ggcttgagtt tttctgtacc tgactctatc ccagctccac
      601 catccttgca aaatatcttg aaagaattgt cagatgatat cggagttaag aaatctcatg
      661 atttgacagc ttgggctgag caaggagtct tgcttcttaa tgcttgtttg actgttcctg
      721 ctggacaggc caatggtcat gctggtcaaa tctgggagcc ttttactgat gctgtgattc
      781 aggtggtcaa tcatctagat agaccagtcg tttttgtact ctggggagct tatgcacgta
      841 agaagaaggc attagttacc aatcctcatc acttgattat cgaatcagcc catccaagtc
      901 ctttgtcggt ttatagagga ttttggggtt ccaagccctt ttccaaggcc aatgcattct
      961 taaaagagac aggacaagag ccaatcgatt ggcttagata aggagaaaat atgcctcagt
     1021 tagcgacgat ttgctacatt gataatggga aagaactgct catgctccat cgtaataaga
     1081 aacccaatga tgtccatgaa gggaaatgga ttggtgtggg tggtaagcta gagagaggag
     1141 agacgcccca ggaatgcgcg gcgcgtgaaa tccttgaaga aacagggctc aaagccaagc
     1201 cagttctaaa aggtgtcatc acttttcctg aatttacacc agatttagac tggtacacct
     1261 atgtttttaa ggtgacggag tttgagggcg acttgattga ctgcaatgag gggacgctag
     1321 aatgggttcc ctatgatgag gttttgagca agccgacttg ggaaggtgac cacacctttg
     1381 ttgagtggct tttagaggat aaacccttct tttcagccaa gtttgtttat gatggggata
     1441 aattgttgga tacccaagtt gatttctatg aataaaggag aaagcagatg ctactaatca
     1501 aaaatggtcg tgtaatggat cccaagtctg gtttggatca agtttgtgat gtcttagttc
     1561 aagatgggaa aattatcaaa attgcgtctg agatcacgga agaaggagca gaaacgattg
     1621 atgctactgg tcttgtggtt gctcctggct tggtcgatat tcatgttcat ttccgtgaac
     1681 ctggtcaaac acataaagaa gacattcata ctggtgccct agcagccgct gcaggtggtt
     1741 ttactactgt cgtcatgatg gctaatacca gtccaaccat ttcagacgtg gagactttgc
     1801 aagcagttct ccagtcagct gccaaagaga agattaatgt caagacagtt gcgaccatta
     1861 ctaaaaactt taatggtaaa aacttgactg actttaaggc actcttagaa gctggtgcgg
     1921 ttggtttctc tgatgacggt attccgcttg agagcagtaa gattgtcaag gaagccatgg
     1981 aggaagccaa aaaactcaat acctttatca gccttcatga ggaagatcca ggtttgaacg
     2041 gtgttcttgg ctttaatgaa aatattgcta gagaacattt ccatatctgc ggtgctactg
     2101 gggtggctga gtacgctatg atggcgcgtg atgtcatgat tgcctatgca actaaagccc
     2161 atgttcacat ccagcatttg tctaaggaag aaagtgttaa agtagtggag tttgctcagg
     2221 ggttaggtgc agaagtcaca gcagaagtag cgccacagca tttctctaag acagaagcac
     2281 ttcttttaac acaaggtagc aatgctaaga tgaatccacc gcttcgtttg gaatcagacc
     2341 gtcgtgccgt tatcgaaggt ctcaaatcag gtgtcatcac agttattgcg actgaccacg
     2401 cgcctcatca tgtagatgaa aaaaatgttg aggatattac caaagcgcca tctggtatga
     2461 ctggcttaga aacatccctg tctctcagct tgacctattt agtagaagct ggtgagttga
     2521 gcttgatgga attacttgaa aaaatgacat acaacccagc caagctttac aactttgaag
     2581 caggttactt ggctgagaat ggtccagcag atatcactat ttttgatgcc aaggctgacc
     2641 gctttgtgga ctcccatttt gcttccaaag cagctaattc accattcatc ggtgaaacct
     2701 taaaagggca ggttaaatat accatctgta agggacaaat cgtctatcaa gcttgatagg
     2761 agttagaata tgaattattt tcgaaaacgt agggagagac aagcgaaatc taatagtgga
     2821 atttactgtc ccgcagctaa tcgttccaaa attcaatatg aaactaaaga aaaagctgac
     2881 catgcggttc aatatgataa cggaggttta gttagaagct attattgtcg tacatgtgcg
     2941 tgttggcata ctacttcaaa atctaataaa cctccgctaa gtttgaaaaa ctatggtctg
     3001 aaactctttg gtttagataa atcagaatag aaagagaagt atgtataaga caaagtgttt
     3061 acgagagaag ttagtattat ttttaaaaat tttcttccca atcctgatct accaatttgc
     3121 caattattct gcctcttttg ttgatactgc aatgacaggt caatacaaca ctatggactt
     3181 ggctggtgta tctatggcaa ccagtatctg gaatcctttc tttacatttc taacagggat
     3241 tgtgtcagcc ttggtgccta tcattggtca ccatcttggt cgaggcaaaa aggaagaagt
     3301 tgcgtctgat ttttaccaat ttatttattt ggccttgggc ctatctgtgg tcttgctggg
     3361 gatggtactt ttcttggcac caataatctt gaatcatatt gggttagaag cagcagtagc
     3421 ggcagtagcg gttcgctatc tttggttttt atctatcggg attatcccct tgttgctctt
     3481 tagcgtcatt cgttccttgc tggattcgct gggcttgacc aaactgtcca tgtacctcat
     3541 gcttttgtta ctccctctca atagcggatt taactatctc ttgatttacg gtgcctttgg
     3601 tgttccagaa ctgggagggg ctggtgctgg tttaggaaca tccttggcct actgggtctt
     3661 gcttgggatt tctgttctgg ttttatttaa acaggagaag ctcaaagcct tacaccttga
     3721 gaaacgaatt ccacttaata tggataacat taaggaagga gttcgtttag gtctgcctat
     3781 tgggggaact gtcttcgcgg aagtggctat cttttcagtg gttggcttga ttatggctaa
     3841 gttttcgtcc ttgattatag ctagtcacca gtcagctatg aacttttcaa gtcttatgta
     3901 cgcctttcct atgagtatct catcggctat ggctattgtc gtttcctatg aagtgggagc
     3961 caagcgattt gatgatgcga aaacctatat tggtctagga agatggactg ctctcatttt
     4021 tgcggccttc accctaacct tcctttacat ttttagggga aatgtggcca gtctttatgg
     4081 taacgaccca aaatttatcg atttgacagc gcgtttttta acttatagtc ttttcttcca
     4141 gttagcagat acctttgcgg caccgcttca gggaattttg cgggggtata aggatacagt
     4201 tattcctttt taccttggtt tgcttggtta ttggggcgta gcaatccctg tggctacgct
     4261 atttgattcc ctaacagatt ttggagctta ttcttactgg atcggcttga ttattagttt
     4321 gattgtgagt ggggcgctct accgttggcg tttaactgtg attatgaaga gatttgaatc
     4381 tttagcaaaa tccaaacgct aaaaagtttg tgaaaaaata ttcttgacaa gaaaatccct
     4441 tgttttcacg gggttttctt ttttattttg tgaaatttct tttagaaaaa ctttgacagt
     4501 atttgccaaa agcggtaaaa tagtaaggta agaagaaagt tagaaaggca agaagatgtc
     4561 aactttagat aaaaatcttt tgctagaaat gttccgtaag atggaagaaa tccgtcgcat
     4621 ggacttaaaa attgcacaat tagtaaagaa agggaaagtg ccaggaatga cgcacttttc
     4681 tgttggtgaa gaggcagcta acgtgggggc tatgttagct ctcaatccag atgatctgat
     4741 tacctcaaac caccgtggac acgggcaagc tattgctaaa gggattgacc tcaacggaat
     4801 gatggctgaa atccttggta aatacactgg aacctgtaaa gggaaaggtg gatctatgca
     4861 tatcgctgac cttgatgctg ggaaccttgg tgccaatggt atcgtaggtg gtggtatggg
     4921 gatcgctgtc ggtgcagccc tcagtcagca aatgcaaaat accggtaaaa tcgttgtctg
     4981 cttctttgga gatggtgcga ccaatgaagg tgttttccac gaagcagtga acatggcttc
     5041 tatctggaac ctgccagtca ttttctattg cattaacaac ggttacggta tctctgcgga
     5101 tatcaagaaa atgaccaata tagaacatat ccatcaacgt agcgccgctt atggaattcc
     5161 tggaatgttc atcgaagatg gtaacaatgt catcgatgtc tatgaaggat ttcagaaagc
     5221 tgtggaccat gttcgcagtg gcaatggttc agtcttgatt gaaagtgtaa cttatcgctg
     5281 gctcggtcac tcatcatctg accctggtaa atatcgtacg cgtgaagaag tggaattgtg
     5341 gaaacaaaaa gatccaatcg aaaacctccg caattacctt attgaaaata acattgcaag
     5401 tgccgaagaa ttggaagaaa tccaagcgca agtaaaggaa gcagtagaag cttctgttaa
     5461 atttgcagag gaaagcccat tcccaccgct tgaatcagcc tttgaagata tttacgcaga
     5521 ctaaggagaa agagataaaa tggaaacaaa aacaatgtcc ttccgtgaca ccattatcct
     5581 tgctatgtct gaggaaatgc gtcgcgatga aaatgtgttc ttgatgggag aagatgtcgg
     5641 tgtcttcgga ggagacttcg gtacttctgt tggaatgctt gaagaatttg gtccagaacg
     5701 tgtccgtgac tgtccgattt ctgaagctgc catctctgga gcagcagcag gagcagccat
     5761 gacaggactt cgtccaatcg tcgatatgac cttcatggac ttctctgtta ttgccatgga
     5821 caatatcgtc aaccaagctg ctaaaacacg ttacatgttt ggtggtaaag gtcaggttcc
     5881 aatgactgtt cgttgtgcag ctggtaacgg agttggctct gccgcccagc actcacaatc
     5941 tctagagtct tggtttactc acattccagg acttaaggtt gtggcacctg gaacacctgc
     6001 ggacatgaaa ggcctgctta agtcttctat ccgtgataac aacccagtta ttatacttga
     6061 gtacaagtca gaatttaacc aaaaagggga agtgccagtt gatccagact acacaattcc
     6121 acttggggtt ggtgaaatca aacgccaagg aacggatgta acagttgtta cttatggaaa
     6181 aatgcttcgc cgtgtggttc aagctgctga agaattagca gaagaagaaa tttcagttga
     6241 aattgttgac ccacgtaccc ttgttccgct tgataaggat atcatcataa actcagtgaa
     6301 gaagactggt aaggttattc tggtcaacga tgcccacaaa acaagtggct atatcggtga
     6361 aatttcagct attatttcag aatcagaagc atttgactat ctagatgcac caatacgccg
     6421 ttgttcagga gaagatgtgc cgatgcctta tgcacaaaac ctagaaaatg caatgattcc
     6481 aacagttgaa agtatcaaag atgcaatccg aaaaacttat aacaaagact agagttacat
     6541 aatataagtt atgtaactaa aataaagctg acgagaaact ttgtatcttt taggtgcaga
     6601 gctcttcgtc attaatatct tatattcgag cacgggctaa aagctcggaa aaaagataaa
     6661 tctccttggc ttcatcgaag ccatcgtcga tttcctattt ttcagtcgct tttgacgccc
     6721 tttgtatcat aaatagaatt ggagaggtca tggctgatga caagctaaga gcgactcctg
     6781 cagctagaaa gttagcggat gatttaggga taaacctcta cgacgtttct ggctcaggtg
     6841 caaacggtcg tgtccacaaa gaagacgtgg aaacttataa agacacaaac gtggttcgca
     6901 tttcgccact tgcaaaacga attgccctcg aacataacat tgcttggcag gaaatccaag
     6961 gaaccggtca tcgtggtaaa atcatgaaga aggatgtttt ggccctgctt cctgaaaata
     7021 tcgaaaacga tagcatcaaa tctcctgctc agattgaaaa agtggaagaa gtccctgata
     7081 acgtaacacc atatggtgaa atcgagcgta ttccaatgac accaatgcgt aaggttattg
     7141 cccaacgcat ggttgaatct tacttgactg cgccaacctt caccctcaac tatgaagttg
     7201 atatgactga aatgttggct cttcgtaaga aggttcttga gccaatcatg gaagcaactg
     7261 ggaagaagac tactgtaaca gaccttcttt cgcttgcagt tgttaagact cttatgaaac
     7321 acccatacat caacgcttca ttgacagaag atggcaagac tattatcact cacaactatg
     7381 tcaatcttgc catggcagtt gggatggata atggattgat gacacctgtt gtttacaatg
     7441 ctgagaagat gagtctttca gaactggtgg tagcctttaa ggatgttatt ggccgtacct
     7501 tggatggtaa attggctcca agtgagttac aaaattcaac attcacaatc agtaatttgg
     7561 gaatgtttgg tgttcagtcc tttggtccga ttattaacca acccaactca gctatccttg
     7621 gtgtcagttc gacaatcgag aagccagttg tcgtcaatgg tgaaattgtg attcgcccaa
     7681 tcatgagttt aggattaacc attgaccacc gtgtcgtaga tggtatggct ggtgctaagt
     7741 ttatgaagga cttgaaagag ttgattgaaa cgccaatctc aatgttaatt taagagcaag
     7801 agtattcatt tttaagatat agataaagga aggaagacat ggccttagaa ataattatgc
     7861 caaaagccgg cgtggatatg acagaaggac aaatcgtcca atggaataaa aaagtcggag
     7921 aatttgtaaa agaaggagaa atccttttgg aaatcatgac tgataaagtc agcatggaat
     7981 tggaagccga agaagatggg tacttgattg ccattctcaa aggagatggt gaaactgtcc
     8041 ctgtaacgga agttatcggt taccttggtg aagaaaggga aaacatccca acagctggag
     8101 cagcatcgcc agaagctagc cctgtacctg tagcaagtac ctcaaacgat gatggtaaga
     8161 gcgatgatgc ttttgatatc gttgtgattg gtggaggtcc tgctggttat gttgcagcca
     8221 ttaaagctgc ccaactcggc ggtaaggttg cccttgttga gaaatctgaa cttggtggaa
     8281 cctgcttaaa ccgtggatgt attccaacca agacctacct tcatagcgct gaaattattg
     8341 aaaatatcgg tcatgctgca aatcgtggta tcgtgattga aaatcctaac ttcactgttg
     8401 atatggaaaa acttttagaa actaaatcta aagttgttaa tactcttgtt ggtggtgttg
     8461 caggacttct tcgtagctac ggagttgctg ttcataaagg aattggtaca atcactaaag
     8521 acaagaacgt cttggtaaat ggttctgaat tgcttgaaac caagaaaatc attcttgctg
     8581 gtggttcaaa agtcagcaag atcaacgtcc ctggtatgga atctccactt gtcatgacta
     8641 gtgatgacat tcttgaaatg aacgaagtgc cagaaagcct tgttatcatc ggtggtggag
     8701 ttgtcggtat cgaactcggt caggccttca tgacatttgg ttcaaaagtg actgttatcg
     8761 aaatgatgga ccgtatagtt ccagctatgg atgtggaagt ttctaagaac cttcgcttga
     8821 tccttgagcg taaaggaatg accatcttga ctggtactaa actgcaagaa atcattgagg
     8881 aaaatggtca acttcgtatc aaggttgaag gaaaagacga tatcatcgca agcaaagctc
     8941 ttctttcaat tggtcgtatg ccagaccttg aaggtattgg agaggttgag tttgaattgg
     9001 atcgtggttg tatcaaggtc aacgaataca tggaaacttc agttccaggc atttatgcac
     9061 caggtgacat caacggtact aagatgttgg ctcacgcagc tttccgcatg ggtgaagttt
     9121 ccgctgaaaa tgcccttaaa ggaaatcatg cagttgccaa attgaatttg actcctgcag
     9181 ccatctacac tcttcctgaa gtagcagcag taggtttgac agaagaacaa gcccgtgaga
     9241 aatacgatgt tgccatcggt aagtttaact ttgctgctaa cggtcgtgct attgcatctg
     9301 acgcagctca aggtttcgta aaagttatcg ctgataagaa atacggagaa atccttggtg
     9361 tacacattat tggtcctgca gccgcagaat taataaacga agcatcaagc atcatcgaaa
     9421 tggaaatcac tgttgaggaa atgctgaaga ccatccacgg gcacccaact tactctgaag
     9481 tgatgtacga agcgtttgca gatgttctag gaatggccat ccattcacct aagaaaaaat
     9541 aaaacgaaga tagattagac tggaaggtta tttccagttt ctatcatata aagtaaaggg
     9601 atatcatgaa atacattatc aatcattcaa atgacactgc ttttaatatt gccttggaag
     9661 aatacgcctt taaacacctt ttggatgagg atcaaatctt cctactttgg attaacaagc
     9721 catctatcat tgttggtcgt caccagaaca ctattgaaga aatcaaccgt gattatgttc
     9781 gcgaaaatgg tattgaggta gttcgccgta ttagtggtgg tggagctgtt taccacgatt
     9841 taaataacct caactacacg atcatctcca aagaagatga aaataaggca tttgacttca
     9901 agagcttctc aactccggtt atcaatacct tggctcaact cggggttaaa gctgagttca
     9961 caggtcgtaa tgaccttgag attgatggta agaagttctg tggcaatgcc caagcctata
    10021 tcaacggccg tatcatgcac cacggttgct tgctctttga cgttgatttg tcagtcctcg
    10081 caaatgccct taaggtttca aaagataaat ttgaatcaaa aggtgtgaaa tccgtccgtg
    10141 cccgtgtaac caatattatc aatgaattac caaaaaaaat cacagtcgaa aaattccgtg
    10201 atttactctt ggaatacatg aaaaaagagt acccagagat gactgaatac gtcttttcag
    10261 aagaagaatt ggccgaaatc aatcgcatca aggatactaa gtttggaact tgggactgga
    10321 actatggtaa atcacctgaa tttaacgtcc gtcgtggaac caaattcact agtggtaagg
    10381 ttgaagtctt tgctaacgtt actgaatcaa aaatccaaga catcaagatt tatggtgact
    10441 tctttggtat tgaagacgtt gctgcagtag aagctgtcct tcgtggggtg aaatacgaac
    10501 gcgaagatgt tcttaaggcg ctaaaaacca ttgatatcac acgctacttc gctggtatta
    10561 gccgtgaaga aatcgctgaa gcggtagttg gataaatcaa aaagaagttg gccaactaac
    10621 caacttcttt ttttgatatt tatttacata atttaaaata cgtaaaatca taaactatcc
    10681 agagcattct tttgttcatc actaacaata tgggtataga ggtcagtgac ttgtgtgcta
    10741 gcatgtccta gttggtgact gactaaaact tgtgatttag tcgcatcata gagcctagtt
    10801 gctagtgtat ggcgcagttt atggggtgtt acacgcactt taaaatcctc tgagtattta
    10861 gcaaccattt tctcaacgct agaagcatcg atacgattag gaacacctct gtagagagtt
    10921 aaaaaaaggg ctgtatctgt tttttccgtt ttatagcgtt gattccgaat ggccagataa
    10981 ttctctaaat aaggtttagc aaaagcagcg acattgactg agtcacgttt gccacctttt
    11041 cgagtaacat caataaccat catttttaga ttgagatctc ttagatctag attaacagct
    11101 tcagataagc gaacaccaga tgccaagaga agggcaataa tggctaaatc tcgttcttta
    11161 tttttgttga atgatgagag agctcgattt gaaagctgtt gtgggtgctc ttgatcgata
    11221 taagttagaa aaccttctgt ttcatcacct agaaagagtt tttgcttgat attttcagct
    11281 ctggcagcaa gggtttcttt ctttttcttg gttgaaactt ttttcattac attacgatag
    11341 aaataaggtt ccccctgatc gttttcaacc tcctcggtta gatacttgta aagactagaa
    11401 agtgctgata aggttcgatt gatagttgtc tgtgaaacac cttgttttgt tgtattagca
    11461 ttcagcaagg gacgttcacg tagataaagg ataaaggatt ccatgtcttt cttagacata
    11521 ttttccaaaa ctgataaagg aatatcggat attttatcag cgtttgaaat accagactcc
    11581 aaaacccagc tgaaaaatcg gtcatattcc ttaaggtatt cgtacagggt tgtaaaactg
    11641 tagggcacag ccagtttaga ttggtagtat tccagaacat accagggcat gagttgtttt
    11701 agtttgtcga ttcgttccag taaaatctca cgtttcatgt attttctcca taattaagta
    11761 tactagtagt atagcataga cttgtacatt tttcaagaaa attatagttt ttcagaaaga
    11821 tgttatagga gtttttcaaa gtgataaaaa gacttagacc tacaaacaaa acagaataag
    11881 gaaaataata aaaatctcac ccactaaact tctgttaata ctacatagct agaaattggt
    11941 ttgattgtcc tgattgtttt atcctatttc tatttcattt cactatataa ttgctattgt
    12001 tttctttttc atgattttaa tcttactgta cagatttgat acagtaaact cctttctagc
    12061 tttatacttt atcatttcta acttaattat agtcttattt ttaataaagt tcaattattt
    12121 atatgtaaaa ttcctcatca gtaaaaaata accgatctca tttctgagaa tcggttttct
    12181 aaataaatca agccgaataa atcaagccga tcatttacat aacataaatt atgtaaatga
    12241 tcgtactaca acaacaaatc tttgactttt ccaatttcac tttttggaat aaccaggtga
    12301 atcatatcac ccagatacat tctggttgag ccgttaactg tttggctctt gccattatgg
    12361 acttgagttg tgatgaggac gttgtgtggt aagttgagtt catgaacttg tttcccagca
    12421 attttatcag aaactggtat ttcgataagt gtaacttctc cttcgctaga tacttcttct
    12481 ggaagcattt tttccagcat ggcttcatag actggcgtac ctttgagcaa atccatgata
    12541 atataagaaa caagagtgac aagaccaagt ggcatgaggt tgcgaatatc tcctaccatc
    12601 tcagttacga ggatcatagc agttaaggga gcttttgata tggctccaaa atagccactc
    12661 attcctagaa tgacaaatat agggaattgc tcttgactga caagtccaag attgacacag
    12721 ataacaccaa ctaaggcacc aagcaaagaa ccaagagcta aaatggggag gaaaattcct
    12781 cctggcagtc cacttccata gctaatcata ctccaaataa agcggattaa aaagtaagct
    12841 aataaaactt ggaaactaaa attttgttca gttaaagaaa ggacaagctg atttccgcca
    12901 ccaatgattt gaggtaagaa gattccgact ggtatgataa ggataaaagc caagatggga
    12961 taataagccc tatccaaatg gattttttga ccaatcaagt cataaactct tccaacgttt
    13021 aatacagctt tctcatagag aaaacctgaa aatccaagga aaattcccat gacgagatat
    13081 atccaatact gatctagggt catgggagga atgttatctg gcatatccaa tactggtgtc
    13141 aaaccgaaca tgagtagaga cacaaagttt gctacgatgc tggctgctag agttgagacc
    13201 cagaaaaagc gcgaaaaatg gtgatagact tcttctacaa caaagagaag tgctgcaata
    13261 ggagcattaa aggctgcggc taaacctgct gcagctccac tggcaatcaa ggaacgttcc
    13321 tctactggac tggatttgag ccacttggca attcctttac caccaactgc tccaagttga
    13381 atgctgggtc cctctcgacc cagcatgagt ccactggcaa tagcaagaat acctagcaca
    13441 tattttttcc aaagaatgcc ccaccagttg agggacatga ggcctttcag ttcggcttcg
    13501 acttgaggaa ttcctgagcc tttaatatct ttttctgacc gtgttagttt ggcactgagc
    13561 caacagatga gtatataaaa caaaaccagt acaaaaagat tgcgcactaa gtacccttga
    13621 tcttgataaa ctccttgtat caggtggaag cccttttcaa ttaagaaacg aaaggatccg
    13681 acgataattc caacgatgag gccgacaatg attcctcgac caacttggga tagtatagtg
    13741 ctggatgcaa aggcgaattc tttcttagaa cggactattt ccgactgttc ctccatggta
    13801 tttcctttca attaattttc ttttttacct aaaaccagtg atttaacggg ttcaaagctg
    13861 gttcggtgaa ttggggtaac tcctagtttt gtgaggcctt ccagatgttt agctgtgcca
    13921 tatcctgcat tagtagcgaa atcatagcca gggaactgct gatcgtattc cttcatcaat
    13981 tcatcacgtg ttaccttggc tactatagat gctgctgcga tagagaggga gttggcatct
    14041 cctttgataa tggaggtttg tgaaatgggc aagtccagtt tcatggcatc aatcaaaagg
    14101 tgctctggtt gagggctgag ctgggagatt gcttcttgca tggctagttt ggttgcttca
    14161 tagatgttga cttggtcgat gacctgatta tctatgatac caattccaat cgacaaggct
    14221 tggtcttgaa cggcttggaa aatctccaga tgtttctttt taggaatttt cttgctgtcg
    14281 ttgagacctt taatcttaca atttttaggt aaaatgacgg ccgcagcgac tacaggacca
    14341 gcaagaggac cacgaccaac ctcatcaata cctacaatta aggtcaatcc ttgcttataa
    14401 agttcttttt cataagaaag catggattcc aagcgcaaat tttcatctaa ttcagcttga
    14461 atggctcttt tacgcttgct gatttccttt tgaactcctg agcgattatc cttttcaagc
    14521 tctaaaaaaa tagggctttc taactccttg actgtcacaa ggagttcttt gatttcttta
    14581 atcgttgcca tcgaggtctt ccaatgtatc taaggtatag ttaccgagtt tgccatcacg
    14641 gacttccttc acgaagagac tgtaaaaacg gtcatagtca tcacggaaac cgagggcgcg
    14701 ggtcatatcc ataataatca caggcgcttc ttcttcaatt ttcatttgtt tgaagcgttc
    14761 agccagcttt tctggataat gttctttgaa ataattgata ccaaaaatgg taacctcatc
    14821 cataggaagc aactgatcct tgatagctcc agtcaatgcc aacttaagtg caacagtttc
    14881 atcctcaaac ttaggccaga gaatccccgg tgtatccaag atttccagat ctttattggt
    14941 tttaagccat tgttgacctt ttgtgacccc tggcttgttt ccaacaacag caatcttttt
    15001 accagccaaa cggttcatca gagtggattt accagcgttt ggaatcccga taatcatggt
    15061 acgcaaggtt tcaatctgaa tcccacgttc tttctggcga gcaatcttat cagccatgag
    15121 cttcttggcc gcatctgtta caacttttac agtcacttgc tctttggagt tgatagctag
    15181 cgtctggatt tcttgtgatt caaaatactg acaccattcc ttggtcattg ctggatcagc
    15241 caagtcggcc ttgtttaaaa tcaagagttt tggtttatca ccaacaatct tggtcaacat
    15301 aggattttga ctagatagag gcaagcgtgc atctactaaa atcgtcacaa aatcaacaaa
    15361 ttttaaattt tcctgcacct gtcgacgcgc tttagacatg tgaccaggaa accattgaat
    15421 agtagccatt gagttttttc ctttcgtagc tctgaagctg ttaatctaga actaagagat
    15481 ctcaatctaa aaatgaatga tgtccaaaca gttcttgttt tatgatataa aaatctactt
    15541 tatattatat catgccttct ttattttgtc cgatgatagc cttttaccct atcttttacc
    15601 ctatatagaa aaaagccatc aaatgatgac ttttcagagg gagcaaaaaa ctgtcctctt
    15661 tatattttaa acatttaaat gtcttcttta aacagtttat taaagaaacc gtctgtgttt
    15721 ttaagaaggg ctttgaatac tttggatttc aagtctactg tatttttgaa atgatcttta
    15781 attttcggat ctgacatacc atcaatatct ttttgaacag cttcagcaaa taaagttttc
    15841 aactgagcat aatttgtaat ttgacgacca tcaatttcaa tagcagtaaa tcctttttct
    15901 gcttttgact taacatcttt gaagtattgt ttcttccact cttcaagatt attgaattta
    15961 tccttagata ctttcttgat aatgaaatca tcacccaata attttttatt ggttttgtca
    16021 gcttcgcctt gatatttgct agatgcataa ctaatgaatc cattttcata accaaaatag
    16081 ccccacatac ggaaagtatt atgcttgaat gatgcagctc caggtgctcc ttggctagta
    16141 ttaccaccat agataccggt cattatatta atatttacgt aagcactatc aaaatcttct
    16201 ggattatatg ttctgtcact aggagcgcca tgttttgtca tcaaattatt gttgactaaa
    16261 tcatcaatgt tgttgataac aattttcttc ttctcatctt cagttaattc acgaacttta
    16321 tcaaattgat gtagctctcc atttttgcga tattgtctat ccattttctt gaaccatcga
    16381 ctaatattac catgtaattt agggataaca gcatcagcct caagatggtc taacatcata
    16441 agagcatcat tataatttct catataacgg tcgatatctt cacgagtttt caatttatct
    16501 ggatcataat tataccattg gtcaccgtca ttttcacgat gataagccat gttaagacca
    16561 agagcaccat attcaccgtt accagattta tcaggtgtct gcaacatacc ttgcgcatag
    16621 gcttcaacgt ctgtaccttg acggtgtcta tgcccaccga agtaaagcat tctatcgttt
    16681 acgtgtgttg tttcgtgagt aaaggctgaa ataccaaacg gactaatcat atttgttccc
    16741 atgaaataaa cttggtcatt attattggga tcttggaaaa tagatgccat agctcccatg
    16801 taccaatttg tagtatgata acgccaagta ggtccatata attcacgaat aggtgcaatt
    16861 ggtttattat tcttatcata acccatacga tttacacctt cgacgttatg atagttttgg
    16921 ttatcccaaa caggtgttgg aaccctattt tgactcttga gtaattggtc acgtacgctt
    16981 ggcaatgcta aacgcgacca gaagtcaaga taagtttgtt gtgcgtgagc aacttcttta
    17041 attttatctt taaatgcttc tcgttcagct tctgtatact taccatattt ttcaaaagag
    17101 ctataagcca ttgtattgta agtcgaaatc aagaacatat gtgcattctt aagagttaat
    17161 agaggtagga tcatacgatt atgaacacca ttattcaaac catcaaatgc acgatgtcgt
    17221 ttattaacaa aatctgggtt cgttgtttta ggctccacaa tgtatacgtt cttagccgca
    17281 tggataaacc aatcatttaa atcagtatcg ttagtgaaga gacgcatgtt gtaatctaag
    17341 aagccatgta attcagactt accaatagtt ccaccaatca tatcacgata agcatccaaa
    17401 gttctgtcac ccttgatatt tcgctcactt gatccaattc gaatcaagaa gtcaagaagg
    17461 tcaactgact taccatagaa atcaggttta aacatcatca agtttttgat agtcatatcc
    17521 ccatacttta tatcatagta acgattaagg taagtaagag ccatcacgat tttagcttta
    17581 ttttcatcca ccttcttaac aagtgctttc atagctgctt cgtcactatt taattgatgg
    17641 tcagcatttt caatcaaaga tttgaccaat ttatcaagat tagctttcgt ttcagaaaaa
    17701 ctttcttcga aataaaggtc tcggatataa ccattcttac gctcatctga attagcatta
    17761 ggatctctag atgtatctcg tttatccatc aaagcacgga cttcgggaga aattaattca
    17821 acagttgcta acctatcttt aatgtcttta atcaattgat cacgattttt atcaaccatg
    17881 tttggtgtat aaacaatgtc atctaatcca tcgatactat actcacgaac ttgcgctact
    17941 ttagactctt tttgatgaac agctttgatt tctttagtct tatctgcata gtgaatcatc
    18001 acatgatcaa tatctgataa atcggtcacg aattgaccat ccttcatacc cgtaacagaa
    18061 aggacttctt tcttagctaa gtttgaatct tctgcaagtt tgttaccttg attgacaatc
    18121 cattctttgt tataaaatgg ttgcagtttc tcaatattac gataagccag atctcgatct
    18181 actttatagt cttgggttga cttatattca tcttctcttc tggttaaacg atttaagcga
    18241 ttgaccacag gttcattgat ttcgtattta tctgcggtaa ttcctgtagc ttcaatttta
    18301 gattttgcct cttcctcaga aataggtctg atacgatttt tatcttttga acgctggtag
    18361 ctagaatgcc catcactaac acctattaca acataatttc gtcttacatt atctcctgtc
    18421 cagtagccat catcataatc aatatcacta gaaccataga aaatttcacc attaggtacc
    18481 ttcatcatgg aaactgaatc ttcgacagaa ccgtggtgct tcatgcttcc tacaacacca
    18541 ccactttcaa tcgcctcagt tacttgaatt gttcccttag caatagattt tttgattgct
    18601 ccttcctgac gaacagtatt gttatttcct tcattttgtg tccaataagc aatgcccgca
    18661 gccttggctt tcttgccaat aagatttgcg ttaacatacg cgcgttcgac gagtcctttc
    18721 cagttctcac caacgatacc agtcaagaat tgtccaccat cgccgacaga agttacgtta
    18781 ccgataaagg ccacatttct gagtgtacct tggttatcaa tcttatcaat aaatccagat
    18841 acccaatctt tacctactat attaccttta accttaacat tttcaatggt agttccacct
    18901 ttaataatat tcgctacagc tgcaacttgg ttcgcccatg gcatatttat gtcaacatta
    18961 ccaagattaa tattcttaat cgttccacca ataacattgc caaataacgg acgtgacaag
    19021 ttatgaatgg tatagtgatt atcaccatca ctcaagagct tacctttgaa atctttcgta
    19081 acatatgatt taccaaatgc tgatacattt gtggcattaa ggtcagcacc caatttaaac
    19141 tcgtcatttg gatgttcttg catatctctc acaagttcat tgaaattgta atatacatta
    19201 ttgacttttg gaactggttt ttcaatgtaa tgaatgtatt catttctagt cttagatgga
    19261 tcgacatgtt gaattaaatc ttgagcgctt gctgtaattt tataaagttc tttttctttt
    19321 tcagttacta actcaatctt atcaactgct aaacgagtta ctttattatc acgactagtg
    19381 atttttaagt acattttctt cacatcttca tcagaaggtt tttcgctcat gaaatcacta
    19441 ggtatttcag taccatcatc atttaccttc actaaattag tagatgaaat atttttaatt
    19501 tcgacctttt tcaactccaa acgcaaagtt ttttcatcca gtttagacgt ttcagaacct
    19561 tgaccacgat cataaatcat tgttgttgca atcttataat ctttaaacaa atccaaattt
    19621 tgtacagcgt cagttaattt ttctttagat aaatcaacct ttttaactac tgtatcacca
    19681 tctttaattt cagctataat acttgatatt tcagcattat ctttattatc aagctcataa
    19741 tttaagttgg cagaacgatt catagcatct tctgttactt tggtcaaggt caaaacggga
    19801 actgtttttt cttttggatt ttcttttgta ccttttacaa gaattttagg tttcatttct
    19861 ttcaaaattg ttaccgtttc aactggttca ctaatttttt tgccatgtaa ctcttcatag
    19921 ctagtaacaa tttgacgttc gccatcctca ccaacttctt taacagaatc atcgcctata
    19981 aatttgctag gatcagattc ttctatagtg gttttaggaa tagtctctgt acgaatatcg
    20041 gtatgtaaag aaggcaactc ttctctttct gatgcaactt ctgaaactgt agatattggt
    20101 tcagtatact ctggaatgtc gttaacaggt ggttcaatca agtttccatt ttcatccact
    20161 cctgttgtac ctactggttc agtgtatgct agtttctcat gaacttcagg ctcaacaagg
    20221 tttgcaccta ttggttgcgt atagtcaggc ttctcatgaa cttctggttc gcctttgtca
    20281 gtcacaacag cttctggtaa tgtcggttgt acttccggtt cgcctttgtc agtcacaaca
    20341 gcttcgggta aggctggttg aacctccggt tcccctttct ctgttacaac tttgggttgc
    20401 tcaactggcg aaacagttga tgctggagaa accgacgaaa cagttttatc atcaagctcc
    20461 aagtaaccaa catatctgta accagaaatt tgcaacacac catcacgtcc agactcatgg
    20521 atgttagcat tcaaattaag tgctgaagca gttgatagtg taactaaacc tgtcgcccct
    20581 acaatcaaaa atgtagctat ttttttattt ctattatctt ttgtgataat cacaataaga
    20641 ctcccgatag ctaacaaacc caatgcagtc ataatagatt gagaactgcc tgtgtttggt
    20701 agtgcgtctt tttcataatc caaagcatat gactctttgg attcatcagg tctaccttgt
    20761 ttgagttgat cacgttcagt ttgtgtcaaa ctactataat ctaagtaatg ataagtcgat
    20821 gcaccaataa ctgacggtgc aaataaaaga ctccccaaga ataccgaacc aacaataccc
    20881 tttattttcc gaatggaaaa tttatctttt tttaataatg acaattctaa tcctccacat
    20941 tcacttttta tttcctaata gtaaacacta ttttttattc tcaaaaattg aacttctaaa
    21001 atcatttgtt tggtcaagat aagctttata tattgctttt ttcagtttaa gaactctact
    21061 atttgtttct gggtaaaatt ttgctacgtc atcttgcgca tcatctctca ctgcttcgac
    21121 aatcattctc tctagtacac ctatatccgt aaccgataca tttcgttgac gactcaatgg
    21181 attattagga ttaataaagt taactctatt tagtttactg aattgttttt ctctttcctt
    21241 atacatatcc ttcttgaatt gtgtccaagt tttatattga ccattaaata ctttttcaag
    21301 tactaattca tctgtaacta aacctacttc tttaccataa gaattaatct tacttcccgc
    21361 cgcttttgca tctttttcat attgatttga gatataaggt accatgccct ctttatatcc
    21421 ttttgcagct aataattcga atgctatacg gcgtcccatt aaatcaccag gagtcccttt
    21481 ctctccacta agagctgaat aaatcggtga aaataaatca attgtataat aaccatttct
    21541 cttatattct tggtctttgt accctctgct agtaataata tcattttcaa ttaaactatc
    21601 aaaagaattt aatttattaa cttcatccat cgttaatctg cgaacaacat ttgtcgcgta
    21661 tacattatta ccgtcttgat caagatcaaa tttattttca atttttctta gtaactcata
    21721 tttttgattt gtttctaaat tagctacagc ttttccttct aaatattcta acatataaat
    21781 tacatcaaac atattatgca tataattatg taggtcttct gcactattaa atcgttgagt
    21841 tggatcagct acttgaagtc ttgttgaatt ttctgaatcc tcatatttca agacagagtt
    21901 aattgttatt gttggatcat atggatgatc cggagcttgt aataatcctt ttgcataaaa
    21961 ctcaggtcct aatccgcttc ttcttccata tcctccaaga taaatctctc tatctgagtt
    22021 atgtgtcatt tcatgagtat atgttacagc tccatcttta tccaacatac gatatgccat
    22081 ataatagaat gcatctccgg tagcatatgc tccgtgtcca ttatgaacaa cattatttcc
    22141 cgcaggtcca aagaagtatt ttatagctgg atgatcagtt tcaaaagtag cttgatgagt
    22201 tactttgtct ttatctttgt cagtaccaaa tttgaaagca tcatatacta gaatacttct
    22261 atataatttt tctttattat cgttatctaa tatcttatac caataatcat aatgatctct
    22321 aaatcgttta gccgcttctt tggcgttatc ttctacaaat ttgtttaact tttctccctt
    22381 aggatattct gaacttctat atctgtcata ggctccaaat ccaatagtag aaatattcgc
    22441 tatcataaac actgtttttt cttcaggtaa agttaatagt ggtaagacca tactttgata
    22501 tttccaagat ggattagtta atctatcata taccccaata gaatatttag ttccctcttt
    22561 tccttgtttt tctcttccct cttcaattgt agatttttct tctacaatat atgcttttgt
    22621 ttgtttttta aaccactcat tgttagaaat tgttggtaag aatacttttc tatatccttc
    22681 taatgcttta aataaacttt cagttccata atttttcgct aataatacat tataagtaat
    22741 tacattattt tttgctaata aattgttaaa tccagattta cctaactcaa taacattatc
    22801 taatgcagaa ctatttgatt taccaaagaa atccaagtgg tacattatta aatctttagc
    22861 attggtttct ccataattaa aattatacca gcgttctaaa tacgttaatc ctaacaataa
    22921 ggcttcctta ttatttttta ttttctcaat tacataatta tctattacct tattgttatt
    22981 ttccactatt gcagcatctg cagtaagtag ttttgataaa ctgtcttcta tatttgcttt
    23041 tgttttttca aattgttcac ctaaatataa ctctgttaat tttatattac cagaaatatc
    23101 taatactttt ctaacgtcag ctgaactata ttgaacagat tt
//
LOCUS       DAVLBN010000032        23060 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLBN010000032 DAVLBN010000000
VERSION     DAVLBN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.032"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            104..1585
                     /locus_tag="VXC24_001250"
     CDS             104..1585
                     /locus_tag="VXC24_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0493364.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1947..2948
                     /locus_tag="VXC24_001251"
     CDS             1947..2948
                     /locus_tag="VXC24_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0493365.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3099..4016
                     /locus_tag="VXC24_001252"
     CDS             3099..4016
                     /locus_tag="VXC24_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0493366.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4027..4917
                     /locus_tag="VXC24_001253"
     CDS             4027..4917
                     /locus_tag="VXC24_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0493367.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4946..6562
                     /locus_tag="VXC24_001254"
     CDS             4946..6562
                     /locus_tag="VXC24_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0493368.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6572..7891
                     /locus_tag="VXC24_001255"
     CDS             6572..7891
                     /locus_tag="VXC24_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0493369.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8101..8173)
                     /locus_tag="VXC24_001256"
     tRNA            complement(8101..8173)
                     /locus_tag="VXC24_001256"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8138..8140),aa:Lys,seq:ctt)
     gene            complement(8438..9709)
                     /locus_tag="VXC24_001257"
     CDS             complement(8438..9709)
                     /locus_tag="VXC24_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0493370.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            9979..10179
                     /locus_tag="VXC24_001258"
     CDS             9979..10179
                     /locus_tag="VXC24_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493371.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10383..10562
                     /locus_tag="VXC24_001259"
     CDS             10383..10562
                     /locus_tag="VXC24_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493372.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10699..10878
                     /locus_tag="VXC24_001260"
     CDS             10699..10878
                     /locus_tag="VXC24_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0493373.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10915..11367
                     /locus_tag="VXC24_001261"
     CDS             10915..11367
                     /locus_tag="VXC24_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0493374.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11658..12128
                     /locus_tag="VXC24_001262"
     CDS             11658..12128
                     /locus_tag="VXC24_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0493375.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12147..13235
                     /locus_tag="VXC24_001263"
     CDS             12147..13235
                     /locus_tag="VXC24_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0493376.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13216..13374
                     /locus_tag="VXC24_001264"
     CDS             13216..13374
                     /locus_tag="VXC24_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0493377.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13484..14518
                     /locus_tag="VXC24_001265"
     CDS             13484..14518
                     /locus_tag="VXC24_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0493378.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14580..16763
                     /locus_tag="VXC24_001266"
     CDS             14580..16763
                     /locus_tag="VXC24_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0493379.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16814..17830
                     /locus_tag="VXC24_001267"
     CDS             16814..17830
                     /locus_tag="VXC24_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0493380.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            17845..18795
                     /locus_tag="VXC24_001268"
     CDS             17845..18795
                     /locus_tag="VXC24_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0493381.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18797..19540
                     /locus_tag="VXC24_001269"
     CDS             18797..19540
                     /locus_tag="VXC24_001269"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0493382.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19551..21347
                     /gene="pepF"
                     /locus_tag="VXC24_001270"
     CDS             19551..21347
                     /gene="pepF"
                     /locus_tag="VXC24_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0493383.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21594..22148
                     /locus_tag="VXC24_001271"
     CDS             21594..22148
                     /locus_tag="VXC24_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0493384.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            22259..22927
                     /locus_tag="VXC24_001272"
     CDS             22259..22927
                     /locus_tag="VXC24_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0493385.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7316 a         3790 c         4882 g         7072 t
ORIGIN      
        1 ataaaagatt ttaggaaaag tcgttatatc atgctatacc tattctttgt ggtataattg
       61 caagaggttt aatccgataa tttataaaga gagaaagata ttcatgagag atttattatc
      121 taaaaaaagt cataggcaat tagaattatt agaattatta tttgaacata aacgttggtt
      181 tcatcgttct gaactagcag agttattaaa ttgtacagaa cgtgcagtca aagatgatct
      241 atcccatgtt aaatctgctt ttcctgactt gatttttcat tcttctacta atggtatacg
      301 cattattaat accgatgata gtgatattga aatggtttac catcatttct ttaaacattc
      361 aactcatttt tcgattttag aattcatctt ctttaatgaa ggttgtcaag ctgagagtat
      421 ttgtaaagaa ttttatatca gttcatcttc gctctatcgt attattagcc aaatcaataa
      481 agtgattaaa aggcaatttc aatttgaagt cagtctgacc cctgttcaaa tcattggaaa
      541 tgagagagac attcgttact tttttgcaca atatttttca gaaaaatatt atttcctaga
      601 atggccattt gaaaattttt catcagagcc actatctcaa ttgttagaat tggtttataa
      661 ggaaacaagc tttccaatga atttgtcaac gcatagaatg ctaaagttgc tcctagttac
      721 gaacctatat agaataaagt ttggtcattt tatggaagta gataaagatt cttttaacga
      781 ccaaagtttg gattttttaa tgcaggcaga aggaatagaa ggtgttgctc agagttttga
      841 atcagaatac aatatctctt tagatgaaga agttgtttgc caattatttg tgtcttactt
      901 tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa tgcgtaaaaa aggatagtta
      961 tgttgaaaaa tcttaccatc tattgagtga ttttattgat cagatttcag tcaagtatca
     1021 gattgaaatg gagaataagg ataatctgat ttggcatctg cataataccg cacatctgta
     1081 tcgtcaagag ttgtttactg agtttatttt atttgatcaa aaagggaata caatcaggaa
     1141 ctttcaaaat atttttccaa aatttgtttc agatataaaa aaagagcttt ctcactattt
     1201 agagactctt gaggtttgtt ctagttcaat gatggtaaat catctatctt ataccttcat
     1261 cactcatacc aaacatttgg tgattaattt gctacaaaat cagcctaaac taaaggtttt
     1321 agttatgagt aattttgatc agtatcatgc aaaattcgtt gcagagacac tttcttatta
     1381 ctgtagcaat aattttgaac tggaagtttg gactgaatta gaattatcaa aggaatcttt
     1441 agaagattca ccttatgata tcattatttc taattttatt attcctccta ttgaaaataa
     1501 gagactcatc tattcaaata atataaacac ggtctcactc atatacttgt taaatgccat
     1561 gatgtttatt cgattagatg agtaaccaaa aataacaaaa aaacgctatt tcgcgtttga
     1621 actgtacctc aaaagttaga cagaaaaaat ctaatttttg gggtgttttt gttaagaaaa
     1681 gaccttcaat catttaagca aaatgtacat ctagatttat agccctctaa aactcttgct
     1741 ttttttgtag aagatacgaa aaaagccata aaaccaaggc ttttcctgtt ttatgtagat
     1801 gtttacacat gaaaattgaa gtattttcaa aagctaattg gagtgatttt attcatgatg
     1861 ggataaatga tctggccaaa aatgattgag aaatagttgc ttaaaaagca tttgcatgat
     1921 actatatatt gaaaggaggt gataatatgg tagaacaaag aaaatcaatt accatgaaag
     1981 atgttgcttt agaagcagga gttagtgttg gaactgtttc acgtgtaatt aataaagaaa
     2041 aaggcattaa agaagtaact ttgaaaaaag tggaacaagc gattaaaact ttgaattaca
     2101 ttccagatta ctatgctaga ggaatgaaaa aaaatcgaac agaaacgatt gcaatcattg
     2161 taccaagtat ctggcatccc ttcttttcag aatttgctat gcatgtggaa aatgaagtct
     2221 ataagagaaa taacaaatta ctcttatgtt ctataaatgg tacaaataga gagcaagact
     2281 atctggagat gttgcgtcat aataaagttg atggagtggt tgccattacc tatagtccaa
     2341 ttgaacatta cttgacgtca ggaattccct ttgttagtat tgaccgcaca tactcagata
     2401 ttgccattcc ttgtgtttca tcagataatg atgcaggtgg aagagaagca gctaaacaat
     2461 taattagtaa aggatgtcag catttagcct ttgtgggcgg acataataca accattaatg
     2521 aaaccaaacg tcgtagaatt tcatttgaaa agtatgtcca agagcataaa atacctctta
     2581 gtatttttga tttggatgag acagttactg actattatgg aaagctagag agtttcttgg
     2641 aagaaaattc ttctatagat ggaattttta caatcaacga ttttacagct ttggatgtga
     2701 ttgaaatact agaaaaaaat ggcaaacgta ttcctcatga tgtccaaatt attggatacg
     2761 atggaattaa aatggctgga gatagagatt atctactttc aactattgaa caaccattgg
     2821 aagaaatggc aaaagaagcg gttcgtattt tgtttgatat aattgatgga aagactgtta
     2881 atttgcagac aatcctacca gtaaaatttg ttgaaggaaa aacaacaaaa aatgaaaata
     2941 agtcttgaca gaaagcgcta tcaatgatag aatgaattca gataaaaaga tttattttta
     3001 aaacaaaaat gaaacgtttc aaaaaaagaa ataaaaagac agcgccaagc gctatctttt
     3061 atagaaaaaa tgaaacgttt caaaaaaagg aggttgctat gaatagcaaa gcgaagcaag
     3121 tttctctttg ggaaagaatc aagaaacaaa aactcttgtt attgatgact gtccccggtt
     3181 tagttttaac ctttatcttt aaatacatcc ctatgtatgg ggttttaatc gcatttaaag
     3241 attacaatcc tttaaaagga attttaggga gtgattggat tggtttttct gagtttacaa
     3301 aattcatatc ctctcccaac tttggtatct tgttagccaa cacattaaaa ttaagtatct
     3361 atggtttatt gcttggcttt ttaccaccaa tcattcttgc gattatgctc aatcaactct
     3421 tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata cgcaccaaac tttatctcag
     3481 tcgttgttat tgtcggtatg attttcctct tcttttcagt gggaggacca atcaacaatt
     3541 ttctttctat gtttggaatg aaggctgact tcttgacaaa tccagacttc tttagaccct
     3601 tatacatctt tagtggtatc tggcaaggaa tgggctgggc ttcaacgctc tacacggcaa
     3661 cattggtaaa tgtagatcca gccttagtag aagcagctcg actggatgga gccaatatct
     3721 tccaacgaat ctggcacatt gatattccag ctcttaagcc tattatggtt atccaatttg
     3781 ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa agcattcttg atgcagacat
     3841 cgttaaattt gccaacttct gaaattatct cgacatatgt ctataaagtt ggtcttgtat
     3901 caggagacta ttcttactca acagcggttg gtttgtttaa tgcagtgatt aacgtagtat
     3961 tgcttgttgc agttaaccaa atcgttaaac gcatgaataa tggtgaagga atttaaggag
     4021 gaaagtatga aaaattcgat tatggataca aaatttgata gacgtatctt actcttaaat
     4081 aaaatcatta ttgtctttat cgttttgatg actttgcttc ctttacttta tatcgtcgta
     4141 gcatccttta tggatcctaa ggttctggtt agtagaggga ttagctttaa tccagccgat
     4201 tggactgtag aaggttacca gcgtgtattc agtgaccaat ctattctaag aggttttatc
     4261 aattctctac tatactcttt tggatttgca gctttaacag tattgctatc tgtgtttaca
     4321 gcttatcctc tttctaagaa agacttggtt ggacgtcgtt ggattaacta cttcttgatt
     4381 gtgactatgt tctttggtgg tggtttagtc ccaacttact tgctcgtaaa agaattggga
     4441 atgctcaata ctccatgggc tatcattgtt ccaggtgctg tcaatgtttg gaatattatt
     4501 cttgctaggg cctatttcca aggattgcct gaagaattag ttgaagctgc tgtcattgat
     4561 ggagcgaatg acttgcagat tttctttaaa atcatgcttc ctcttgcaaa accaattatg
     4621 tttgttctct tcctctatgc ttttgtagga cagtggaact catactttga tgcaatgatt
     4681 tatatcaagg atccaaactt ggaaccattg caacttgtac ttcgtaaaat tctcattcag
     4741 agccaaccag gtcaagacat gattggagca caagcggcta tgaatgaaat gaaacgttta
     4801 gctgaattga ttaaatacgc aactattgtc atttccagct tgccattgat tgttatgtat
     4861 ccattcttcc aaaaatactt tgataaagga attatggctg gttcacttaa aggataaaaa
     4921 aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca ttctcaaaat cagcagtttt
     4981 gttgacagct agtttagcag tacttgcagc ctgtggctca aaaaatacag cttcaagtcc
     5041 agattataag ttggaaggtg taacattccc gcttcaagaa aagaaaacat tgaagtttat
     5101 gacagccagt tcaccgttat ctcctaaaga cccaaatgaa aagttaattt tgcaacgttt
     5161 ggagaaggaa actggcgttc atattgactg gaccaactac caatccgact ttgcagaaaa
     5221 acgtaacttg gatatttcta gtggtgattt accagatgct atccacaacg acggagcttc
     5281 agatgtggac ttgatgaact gggctaaaaa aggtgttatt attccagttg aagatttgat
     5341 tgataaatac atgccaaatc ttaagaaaat tttggatgag aaaccagagt acaaggcctt
     5401 gatgacagca cctgatgggc acatttactc attcccatgg attgaagagc ttggagatgg
     5461 taaagagtct attcacagcg tcaacgatat ggcttggatt aacaaagatt ggcttaagaa
     5521 acttggtctt gaaatgccaa aaactactga tgatttgatt aaagtcctag aagctttcaa
     5581 aaacggggat ccaaatggaa atggagaggc tgatgaaatt ccattttcat ttattagtgg
     5641 taacggaaac gaagatttta aattcctatt tgctgcattt ggtatagggg ataacgatga
     5701 tcatttagta gtaggaaatg atggcaaagt tgacttcaca gcagataacg ataactataa
     5761 agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc ctgattgata aagaagcttt
     5821 cgaacatgat tggaatagtt acattgctaa aggtcatgat cagaaatttg gtgtttactt
     5881 tacatgggat aagaataatg ttactggaag taacgaaagt tatgatgttt taccagtact
     5941 tgctggacca agtggtcaaa aacacgtagc tcgtacaaac ggtatgggat ttgcacgtga
     6001 caagatggtt attaccagtg taaacaaaaa cctagaattg acagctaaat ggattgatgc
     6061 acaatacgct ccactccaat ctgtgcaaaa taactgggga acttacggag atgacaaaca
     6121 acaaaacatc tttgaattgg atcaagcgtc aaatagtcta aaacacttac cactaaacgg
     6181 aactgcacca gcagaacttc gtcaaaagac tgaagtagga ggaccactag ctatcctaga
     6241 ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc aaatggcgtt tggatcttat
     6301 caaagaatat tatgttcctt acatgagcaa tgacaataac tatccaagag tctttatgac
     6361 acaggaagat ttggacaaaa ttgcccatat cgaagcagat atgaatgact atatctaccg
     6421 taaacgtgct gaatggattg taaatggcaa tattgatact gagtgggatg attacaagaa
     6481 agaacttgaa aaatacggac tttctgatta cctcgctatt aaacaaaaat actacgacca
     6541 ataccaagca aacaaaaact agaggttgat tatgggagat aagaaataca cagtagaaaa
     6601 agccaatcgt tttatagcag aaaataaaca tctcgttaat actcaatata agcctgaaga
     6661 acatttttca gctgagattg gttggatcaa tgatccaaat ggatttgtct attttcgtgg
     6721 agaataccat ctcttttatc aattctatcc atatgatagt gtttgggggc ctatgcactg
     6781 gggacatgct aaaagtaagg acttggtgac ttgggagcac ttgccagtgg cacttgctcc
     6841 tgaccaagat tatgaccgaa atggttgttt ctcaggctct gccattgtca aggatgatcg
     6901 cctctggctc atgtacactg gacatatcga agaagaaacc ggtgtccgcc aagtgcaaaa
     6961 tatggcattt tcagatgacg ggattcactt tgaaaagatt tcccaaaatc cagttgcaac
     7021 tggatcagac ttgccagatg agttgattgc tgctgatttc cgtgatccaa aactctttga
     7081 aaaagatgga cgctattact ccgtagtagc tgccaaacat aaggataatg tgggctgtat
     7141 cgttctacta gggtccgata acctagtaga atggcagttc gaatccatct ttttaaaagg
     7201 ggtagaacac caaggcttta tgtgggaatg cccagattac ttcgagttag atgggaaaga
     7261 ttgccttatt atgtcaccca tgcgttatca gcgtgaggga gactcatatc ataacatcaa
     7321 ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa aaatgtttta tcccagaatc
     7381 agttcaagaa attgatcatg gccaagactt ctatgcgcct caaacattgt tggacgatca
     7441 aaatcgtcgt atcctgattg cttggatgca gacatggggg cgtacccttc caacccatga
     7501 ccaagaacac aaatgggcat gtgccatgac tttacctaga attttaagat tggaagatgg
     7561 caaactaaga caattccctg ttaaaaaagg ccaatatcaa atccaaatag ataaagattg
     7621 tcattaccac ttaggaaatg atatagatta tcttgaattt ggttatgata gtaatgcgca
     7681 gcaagtttac attgatcgta gccatcttat tcaaaaaatt ctaggtgaag aagaacagga
     7741 cactagtcga cggtatgtag atattgaagc taaagaattg gaagttgttc tagataaaaa
     7801 ttccatcgag atttttgtca atcaaggtga agcaagcttg actgcaactt attacttaac
     7861 ggtgccagct gagctatcac gaattgatta aaaattaagt tatttctcct aaagaaaaag
     7921 ttctctttct aaaatagtgg aaagaggact ttttgtgttt tgggtatata agcttagttt
     7981 atggtatttg taaaattggt gttggattat gatttaagct agttttctaa agaatttgaa
     8041 aaaaatttta tttaagcaaa aaaaaccctt ggttccaagg cttttcctgt tgtatttata
     8101 tgccccctac agggatcgaa cctgtgaccc acggattaag agtccgctgc tctgccagct
     8161 gagctaagga ggcaaagaaa aaagctgtat tggtgccgaa acttcacggt ttgtattgaa
     8221 cccgcgcaat taagcaggtg ggcaactcgc tctaactgaa gctgtttccg tgtgagacgg
     8281 cctacatgct gttagaagac ttttgtttcc ctaataatac aaaaaatagt cggtcaacac
     8341 ttaagtgtga agtcgtacac cacagcgttt ctatacttat atgataccac tttttcaaaa
     8401 aaaatcaaga ggaaagtgca attttttgaa aaggatttca gatttttcgc aaacggtcga
     8461 tagcttcctt tctttgagcc aaagcccgtt catatttacc agtatcttct gcttggaaat
     8521 agtgatgatt acgaattttt tctggcagat agtcttgctt gacccaattt ccaggatagt
     8581 tgtgtggata gagatagtct tgggcattcc ccagttcctt gcttccactg tagtgcccat
     8641 cacgtaggtg tcgcggaata ggcaagtgcc ctgatgtttt gaggtcagca agtgccttat
     8701 ccatagctac ataggctgag ttggattttg gagaaagggc caaatcaatc acgacattgg
     8761 caatgagaat gcgggcttct gggaacccaa tcttctgggc agcatccaga gcagtcacgg
     8821 tatgaatctg ggcctcagga ttggctaagc cgatatcttc ataggcgata acagtcaagc
     8881 gacgagcgag actaggcaga tccccagcct caatcaagcg ggcagtatag tggagactgg
     8941 catccacatc tgagccacga atagactttt gcagggcaga tagaacatca tagtgaccgt
     9001 ctccatcctt gtccatagtg atgtagcttc tctgaagact attttccatg atgtctaagg
     9061 tgatgtggcg aatgccctcg tcattctcag gggtagagag aacagctaag tccagtgagt
     9121 taaaggcaga gcgaaggtct ccgtttgtag aggttgcgat gaaatccagc gcatcctcat
     9181 ctagttctat tggaaaatca aaaccacgtt cagggttact tagagctatc tgcagggcct
     9241 ctttgacgtc ttggttagac agaggttcca actcgaaaat ttgaactcgg ctacgaatgg
     9301 caggagtgac agagaagaaa ggattttcag tcgttgctcc aatcatgatg accagtccac
     9361 tttccaagag aggcaagagg aagtcttgct tggtcttatc tagtcgatga atttcgtcta
     9421 gcaataggac gagaccacca gaaaatttag cttcttccga gatttcttgc agtcgctttt
     9481 tactatcaac tgtcgcattg aaagttcgaa aggcatactt ggtcgttcca gcgatggcag
     9541 aggcaatact ggttttgccg attccaggag ggccatatag aatcatggag gacaggcggt
     9601 tggcttccac catgcggcgg atgatttttc caggtccgac cagatgctcc tgaccgatga
     9661 cctggtcgat ggttttaggg cgcatgcgaa gcgcgagatt gtctggcata gcagtccttt
     9721 ctagcgtgga tttgagtaga atgactcatc tactatatct tactatgtcc attctagcct
     9781 attagttgtg atatttcaat ggttttgtaa taatcaggga gtgagataga atctttttta
     9841 ctatttaatt taatgaggag aggtatcagc atgagagatt tgattttcct taaagctcaa
     9901 aataggatag ttgagcctaa agaagtggaa gtgctgactt gagaaataat attgctgaat
     9961 gtcattgtat gaactataat gaaaagagag gtgataagta atggaaatga tggaccaagt
    10021 caggaaattt tgatttttac aaaacaaatt cgtcattgga ttcttagtga tcaagttatt
    10081 tcagggaaaa gaaaactttt cttccgggaa gatactccaa aagagatttt agatttgtac
    10141 gaaaacatta aatctaaact tgattttgct taccaataag tttattctaa taatgggttg
    10201 aaaaaatatg aaaaatagaa taattgatgt ttttgaagta gtaaatcgca tccttgtaat
    10261 aactgttgaa aatcctgatt tcgaagactt gagagttaat catactcaat gaaaatcaaa
    10321 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggtaaggcga cgttgacgtg
    10381 gtttgaattt gattttcgaa gagtatcagt ttgtaaaaat tggagataaa aaatatagag
    10441 tacgcagtgt tcctatgatt cattcaactc cgcctcaatc tgtcttagat cgagatactt
    10501 ttacaattga ctatacagat gatgaattgc tcgataaaga agcagttttt actactcatt
    10561 agaaaaatag gtctgaataa attggcttcc cttagaacca catctagggg cttttatgta
    10621 taatagaata ataagtatca ctcctttaca atacgtgtaa cacgtgttat aatggtgttg
    10681 tcaggaggta aaagcgctat gcctatgaca caaaaagaga tggttaaact ccttacggcc
    10741 catggttgga taaagactag aggcggtaaa ggctcccata ttaaaatgga gaagcaaggg
    10801 gaaagactta tcacaatccc tcatggtgag ctgaataagt acactgaaag agggataaga
    10861 aagcaagctg ggttgtaaaa ttcagcccct gttttttgat atggaggtag tgaaatgtta
    10921 gttacgtatc cagctttatt ttattatgac gacacagacg gaacagaagc gacttatttt
    10981 gtccatttcc cagattttga atactcagct acacaaggag aggggatttc tgaggctttg
    11041 gctatggggt cggagtggct agggataact gttgcagatt tgatagagag tgatggagag
    11101 ttacctcagc catcagatat caatagcttg tctttaattg ataatgatcc ttttaaagat
    11161 gatgaagatt tcgtgtcaac ctatgacctt gataaatctt ttatttctat ggtatctgtt
    11221 gatgtatcag aatacctagg aagtcaggaa cccataaaaa agactttgac cataccaaaa
    11281 tgggcagata agttgggacg agaaatggga cttaactttt ctcagacttt gacagacgct
    11341 attgcagata agaaagttca agcctaagat taagcgtggt atcgtggtaa tagtcaataa
    11401 aaaagcacgt ccacttgtgc tagttactcg cctattgatt ttatagattt attagccctt
    11461 tcgcgggctt tttatattga tttttatgag aaatgaagaa atcagacttt taagaaaatc
    11521 actgatacca agggtttaaa tgaggtaata tggtataatt aggacataaa ataattttgt
    11581 ggtaagatgg tagtatctat tttagcatat ttccgagcaa tcggggcgat taaagagtcg
    11641 catagaaaga ggacaaaatg gcaacatacg gatttttaga tgttttagag gaagagttgg
    11701 acaagaactt tccctttgac tttgagatta gctgggacaa acgcaaccat gcggtagaag
    11761 tgagttttct attggaagcg caaaatgctg caggtgtgga gatggtggat gaagacggag
    11821 aggttttatc agatgacatt ctttttgagg aagcggtcct tttctacaat cctgccaagt
    11881 caacagtcaa tgaggaagac tatttgactg ttattcctta cctgcctaaa aaaggatttt
    11941 cccgtgaatt tttagcttat tttgcgcttt tccttaaaga tactgctgag gttgggctag
    12001 atgtcctcat ggactttttg gaagacccag aagcagagga atttgtcatg gaatggaacc
    12061 aagaagtctt tgaagaagga aaagttggct tggaagaggg agaattttat ccttatccaa
    12121 gatactagga gttggttgga ggtgttatga agaaaattgg gacttatttg gtttatgtgc
    12181 tagcttttgt ctttattatg ctagcttttg cttgtggaac aatcgcattt gcagagttgg
    12241 ggtattccgc agttttagcc tttacttttg gttatgcctt cgctcttcta agcatgtatt
    12301 taatctttat tcttcatgag ctgggtcatg ctttttgtgg ctacttgaca ggctatcggc
    12361 tggtggcttt tggattagga cattttattt tgaccaaaaa gtcaggcagg tttcatctta
    12421 gtagaacagc cattctgaaa aatgttggtg ctcaatacat tggtttaaaa gaggatgaaa
    12481 gcgatcaaag aatcatcctg atgctttcag gaggcttgat ggttcatctc ggcttgatat
    12541 tattggcgat agtgtttgga tttttgacaa gaagctggta ttttgcaggg acttggattt
    12601 ttcttaattt atctttcttc ctaaataaca ttttgccagt cgacatcacc gatggagcaa
    12661 aaatttggga attactacaa caccctgaaa ataccaaata cgcctacctg gtattgagac
    12721 attctgctca aactttgctg gctcctcaag aatatgattt gaaagacttt gttcaagcag
    12781 ttcctgagga tgcacgaggg agttttgcgg atggtgtatt aggtatgcaa ggtgaagttt
    12841 ccattttgga agggaaggaa gaagtagcta aacagcagtt tcaagcatta cttgagagga
    12901 caactactcc gatgatgcag acagttgccc aactatccct gcttcatatc gccttgttgg
    12961 aaggagattt tgagcaagcg gagcaatatg ctagtattcg acaggtcaaa tcgtttctgt
    13021 ctctcaaact gtccaatctt caagtgatac aagcttggta tcaatttaag gtaaagaaag
    13081 atgtagatcg aactcgtaag gctctcaaga ttgctagaca gaaaatggat agtagtcgaa
    13141 tgttgaggga cgagaaacgc tattatgaaa acttgttagc agagctggaa aaggaaatgt
    13201 tagaaggaac tgaagatgga actagaaatt tctgatttcc caggctgtaa gattgctttg
    13261 ttttgtgggg ataagctctt gactatctta cgtgatgata aggcaagtat tccctgggcc
    13321 aatatgtggg aactgccagg tggtggaaag agtgtcaggg aaaatctgat atagttttgt
    13381 attaaaagaa tatcctttca aggttattct tttttaattt tgtcccaaaa taattgactt
    13441 tgtcccgaaa atatagtatt atttgtgtaa ggaggaatga atcatgaaaa aatcagatgt
    13501 tcttgattta ataaagtatc attatgaggg cagagagaca gaatttagaa atcaatccat
    13561 agcaattgct cggaacttca ataaacatgg tgatacacaa atagcacaat atattatggg
    13621 gttaatgtct caaagtgata gattcatgcc acaaatagaa aatcctagtg agtatttgac
    13681 tcctgctaaa ctagatattg gtcctctccc attgcctctt tcaattatga atgatttaaa
    13741 aggaataata aacgctgtca atcatcatat tggaataaat aaatttttat ttgtgggatc
    13801 tccaggtact ggaaaaactg aaagtgtaaa gcaggtggct agacttattg gcaaggaatt
    13861 acttgtagta gatttcagtc acttagtaga tagtaagcta gggcaaacag tcaaaaactt
    13921 agcaactctt tttaatgaaa tcaataatct tcctttcaag caaaattata tcatcctatt
    13981 tgatgaaatt gattccatag tgttggatag ggttaatcag aatgatttaa gagaaatggg
    14041 acgagtgact tctgcctttt taaaggagtt ggataggctg tcaccagaaa ttgtattaat
    14101 tgcaacaaca aatctttttg aaaatcttga taaagcagtt acgagaagat tcgatgccat
    14161 aattgacttt gaccgttata ctgatgaaga taaagtagaa gtagctacta ttattttaaa
    14221 tgagttatta aagcaattta agaatgtagc tagagattta aaattattta aaaaaattat
    14281 caatagtgcc aatgtaatac cgaatcctgg tgatttgaga aactcaataa gaacgtcatt
    14341 ggcatttagt gacccatcag atccgcatga ttaccaaaaa cgcctgctaa gaagtttgca
    14401 taatggtaga aatttatcta tttctaaatt atcgaagcta ggttttactg ttagagaaat
    14461 tgagattttg acaggtattt ctaagagtag tgtatcacga gagttaagcg aggattaaaa
    14521 tgaatacatt attgacatta cgaggtaaaa gttttacaca aaaatcaaga aataatggta
    14581 tgggaccaat aactataccc aaaaaaacaa taattacatt ggaacatttg aagtatcttc
    14641 atttttcatt agaagagacg aaaacatatt gggagaaaaa taacattatc gatggtattt
    14701 tgatcagtat ttactataat cgaattgttg ccaaaagtaa ccgtattaat ggctatttca
    14761 atgtaggagg agggaatcca ttccctaatg atactattgt gggagcaaaa ttcaatgatg
    14821 agaagacaaa acatattgtt actcattata tttctagaga tgctcttaat aaaacaataa
    14881 ccgttttaag taagataatt gaagtttttg aggaacattt tgatagagcg ataacatgtg
    14941 agatgttttc tgattcatca acgtttgctt ctataaattt ttcggagtat ggtatttcaa
    15001 aaagcaaatt tcaacagtat ttgagagatt cttgctttat tgagaatttt ggagttgagc
    15061 acactactgt ttctgatatt caaaattcta tcgtgacatt ttatgatgtc catacagaca
    15121 tttttagatt actgaataaa ttaaatattg atatttcaga agctaatatc atgaatcaga
    15181 ccacggtctt gcttgatgaa aaaaatattg aattgctact atcaaaagcg ccctatcttg
    15241 tctccatgat tgtggaagat ttttctaagt tatctgtaga tgatttttct ttagataata
    15301 atgatttaaa aataaatctt ccatctccaa tgaacgaacc agttgttggc gttattgata
    15361 ccttatttga caaaagagtt tactttaatg agtgggtaga atatcatgat tttgtctcac
    15421 ctgatattag caaagatagc caagattaca agcatgggac agctgtgact tctttaatcg
    15481 ttgatggagc caatttgaac cctaatctgg atgatggttg tggaaatttt agagtgaggc
    15541 attttggtgt gtcactacaa agtggattta attcatttac aatcataaaa cagataaaag
    15601 agattgtttc tcagaatgct gatattaagg tttggaatct ttctttaggg tccaatgatg
    15661 aaataagaga aaattttatc tctgcagagg gagcattatt agacgaaatt caatttgaga
    15721 atgatgtaat ttttatcata gctgggacaa atgcttcagt aataaatggg aaacgcaaaa
    15781 gaataggtgc tcctgctgat tcacttaatt ctataatagt aaattctgtt gattttaata
    15841 atcaatcagt gtcatattca cgagagggta ttgttttatc attctttgtt aaaccagatg
    15901 tgtcatatta tggaggagga aatggtgact ttataaatgt ttgtgaacct ctaggattag
    15961 gtcgtgtagc tggaacaagt tttgcggcac cttttattgc aaggaaaatg gcctatctca
    16021 ttcatattat gggacttagc cgagaagaag cgaaggcttt gctaattgat gcagcaatac
    16081 cctggaatga taagaaaaca ttcactgatt tatctttgat aggaaatggt attgttccaa
    16141 taaaaatgga tgatatttta tctacacctg atgatgaaat taaatttatt gtgtcagata
    16201 tctctagggc ttatgatacc tataattatg attttccagt acctatttct agtgagagtt
    16261 atccatatgt agctaaagca acaatgtgtt atttccctaa ctgctcaaga aaacaagggg
    16321 ttgattatac aaatactgag atgcagctta cttttggtag gttaaagtca gacggtatca
    16381 aatcgataaa taaagacaac cagcatgccg aagatacccc aggatatgtg agagaaaacg
    16441 ctgctagaaa tatatttagg aaatgggata atgtcaagca tattggagag tcgtttactt
    16501 ctcgaaagag agctaaagca attttaaatc catctaatcc tcagtggggg atgagtatta
    16561 aaacaatcga acgtttgaaa agcggtgatg gacaaggagt acgttttggt gtagtagtta
    16621 cattaaaaga attaaatggg gttaatcgta ttgaagattt tattcagcaa gctgaattac
    16681 gcggttggct agttaataga ttgcaagtag aagctcaagt agacctcttt aatagtttaa
    16741 atgaagaaat tgaatttgaa tagtggatat tttatcctta ttttagatct taggaacaca
    16801 agagggcaaa gatatgaata ttacttatat agttggaaat ggtttggatt tgcaatatgg
    16861 tttgaaaaca agatataggg atttctacga attccaaaat aaggtttata taagtaggac
    16921 agagaacgag gaaaaatatt caaatttcat ttatgagtct ctattttctg ataaagtaaa
    16981 tgattatgaa aattggtcag attttgaatt gtcaattggt aaattgacaa aagataacga
    17041 cctcatctcc tcaagtatag aaataaagga gaaatttata gatgatttta gtgaagtagt
    17101 tgatgattta agagaatatc tacgcataca acaagaaaaa aatcttgaga aaggtaatgc
    17161 aattgacttt ataagcactc tagatgatat gaggacctct ctccctgtaa ttaatcaacc
    17221 tgctatcgat aaaaaataca atgagaatcc acatcaggac gacattgtaa atatagtaac
    17281 acttaattat acacatgtaa tcgataaatt atataatggg tcagcaaaat cattcaggaa
    17341 tcaattacga gctaatcttt ataattttta tattgagcca ccaattcatg cacatgggac
    17401 ggtggatgtc tgcacggttt taggggttag tgatgaaata caaatttcaa atagtttaga
    17461 agaacaaaag gaatccctaa taaaaagttt agttttaaaa aactatagag aaaatatgga
    17521 tgtaaagaat agtgatatta taaaaaattc tgacatcatt attctctatg gggtttcttt
    17581 gggagaaact gataggtata tctggagtca gattgctgaa cgatcaatca gcggttctgt
    17641 tcctgtcata atttaccact atgtacctca ttttgatccg gggaatccca ttagagcaaa
    17701 acgcctatat agaaatgtag aagataaatt catacagaat agtggtatag acttagagtt
    17761 agagaaaaaa ttaagagaca accttattgt cgttattggt aagactattt ttgatctaat
    17821 agagaggtaa ttttaaaaaa caaaatggaa acatggcaag agttaaaagt tacagtgaag
    17881 cgtgagggag aggagttggt ttccaatctc ttgattgagc tgggagcgca aggtgttgcg
    17941 attgaagaca gtatggacta tgtgggaaat gttgaccgct ttggcgagat tttcccagag
    18001 gtggagcagc aagaagaaat cgtagtgaca gcctactacc ctgacacggt ggatgtgaca
    18061 gtggttgagg cggacttgca ggctcgctta gcagaattga cggattttat ggatttggga
    18121 gagttaaaaa taggtacgac tgtcttggct gaggaagact gggcagataa ctggaagaaa
    18181 tactatgagc cagctcgtat cactcatgat ttgaccatcg ttccctcttg gacagactat
    18241 gaggcgactg cgggggaaat gattatcaag ctggatcctg gcatggcttt tggtactgga
    18301 acccacccaa ctaccaagat gagccttttt gccttggaac aggttcttcg tggtggcgaa
    18361 acggtgctag atgtggggac tggttcaggg gttctctcta ttgccagctc gcttctgggg
    18421 gctaaagaaa ttttcgccta tgacctagat gatgtagcag ttcgtgttgc tcaggaaaat
    18481 attgaactta accctggaat ggaaaatatc cacgttgctg ctggagactt gcttaagggt
    18541 gttgagattg aggcagatgt gattgtagct aatatcttgg cggatattct cattcatctg
    18601 acagacgatg cctatcgttt ggtcaaggat gaaggctacc tgatcatgag tggcattatc
    18661 aaggacaagt gggacatggt gcgcgagtcg gctgagtcag ctggattttt ccttgaaacc
    18721 cacatggttc aaggggaatg gaatgcctgt gtctttaaga aaaccaagga tatttctggt
    18781 gtgattggag gctagcatgc agcagtattt tgtaaaaggc agtgctatct ctcctgtcac
    18841 tatcgaggac aaggaaacca gtaagcatat gtttcaggtt atgcgcttga aagaagagga
    18901 tgaggttacc ttagtctttg atgatggcat caagcgcttg gcgcgcgtgc tggatatgga
    18961 aaatcgtcag tttgagttgg tccaagaatt aaatgacaat gtggaactac cagttcaagt
    19021 gaccatcgca tctggatttc ccaagggaga caagctggag ttcatcgctc aaaaagtaac
    19081 cgaactgggt gctagccaaa tctgggcctt tcctgcagac tggtcagttg ccaagtggga
    19141 tggcaagaaa ttgggtaaaa aagttgaaaa actagaaaaa attgcccttg gagcagccga
    19201 gcaaagcaag cgtaatattg taccaagtat taaacttttc gagaaaaaag cagattttct
    19261 aactcagctg gaccagtttg actctatcat agtagcctat gaagaatcag ctaaagaagg
    19321 agaagccgct gcgcttctgc aagcagtcac tggtcttgaa acaggagcca aactgctctt
    19381 tatctttggt ccagaaggcg gtctctcacc tgcagaaatc gaaagttttg aagctaaggg
    19441 agccgttttg gtaggcctag gtcctcgtat tttgcgagca gaaacagcac cgctttacgc
    19501 cttatcagcc cttagtgttt tagtagaatt agagaaataa gaggaagaaa atggaacaaa
    19561 aacaccgttc agaatttcca gagaaggaac tttgggattt aacagctcta taccaagacc
    19621 gtgaggattt cttgcgtgca atcgagaaag ctcgcgaaga catcaaccag tttagccgtg
    19681 attacaaggg caatcttcac acttttgagg atttcgagaa ggcctttgcg gaattggaac
    19741 agatctacat tcagatgagc catattggca actatgcttt tatgcctcag acgacggact
    19801 atagcaatga cgaatttgca aatattgctc aagctgggat ggaatttgaa acagatgcca
    19861 gcgtagcctt gaccttcttt gacgatgcct tggtggtagc agacgaggaa gtcttggacc
    19921 gtttgggtga attgcctcac ttgacggcag ctattcgtca ggccaaaatc aaaaaagccc
    19981 actatctagg ggctgatgtg gagaaggcct tgaccaatct cggtgaagtt ttctatagtc
    20041 cgcaggacat ttatactaag atgcgagctg gggattttga aatggctgac tttgaagccc
    20101 atggcaagac ctataaaaac agctttgtca cctatgagaa tttctaccaa aatcacgagg
    20161 atgctgaggt tcgtgagaaa tccttccgtt ccttctcaga gggacttcgt aagcaccaaa
    20221 atacggctgc agcagcctat ctggctcagg tcaagtctga aaaactcttg gctgatatga
    20281 agggatacga ctctgtcttt gattatcttc tagctgaaca agaagtggac cgtgtcatgt
    20341 ttgaccgcca gattgacctc atcatgaagg actttgcacc agtcgctcag agatacctca
    20401 agcatgttgc caaggtaaat ggtcttgaaa agatgacctt tgcagactgg aaattggact
    20461 tggacagcgc cctcaatcct gaagtgacta ttgacgatgc ctatgatttg gtcatgaagt
    20521 cggtagaacc tttggggcaa gaatattgtc aggaagttgc tcgttaccaa gaagagcgct
    20581 gggtggactt tgctgctaac agtggcaagg attccggtgg ttatgcggcg gacccatatc
    20641 gcgtacaccc ttatgtactc atgagctgga caggccgttt gagcgatgtc tataccttga
    20701 ttcatgaaat cgggcattct ggtcaattca tcttttcaga caatcaccaa agctatttca
    20761 acgcccacat gtcgacctat tatgttgaag caccgtcgac cttcaatgaa ttgctactca
    20821 gtgattactt agagaaccag tctaatgacc cacgtcaaaa acgcttcgct ctggctcatc
    20881 gcttgacaga cacctacttc cataatttca tcacccacct cttggaagcc gccttccagc
    20941 gtaaggtgta tacattgatt gaagaaggag aaaccttcgg agcaagcaaa ctcaacagca
    21001 ttatgaagga agttttgaca gatttttggg gcgatgccat tgaaatcgac gacgatgcag
    21061 ctttgacttg gatgcgccaa gctcactact atatgggctt gtatagttac acttactctg
    21121 ctggtcttgt catctcgaca gctggttacc ttcatcttaa aaactcagaa actggagctg
    21181 aagactggct caatctcctc aaatcaggtg gtagcaagac accacttgag tcagccatga
    21241 ttatcggtgc tgatatttca acagacaaac cactccgtga taccatccaa ttcttgtctg
    21301 acacagttga ccagattatc gcctacagtg ctgagttggg ggagtaaggg gaatagaaaa
    21361 attttctaga atgatgttta tgggcttgtt aagcgtcatt ctatttgtct tagttgtagc
    21421 tattttcaaa aatgtcgttg aaggtcgtga tgttaaattt gaacttactg tagaactggt
    21481 attgatagtt atttacgtca ttttatatca gattgtattt aattgagaat tcaatattga
    21541 gtcatttaag actgcctttt tgaacagttg ctagaaatgt agaggtattg accatgtatc
    21601 aagatttact aagaaaaata gcagaagaaa aaccaaatta taaccaggaa gaaatccagt
    21661 ggttgtttga tcatttggga aatccttctc cagaaattcg tgatgacctt tcaaatcaag
    21721 gcttgcacta tctttcaaaa gaaaaggata caacaggttt ctcaagtcag tatggttggg
    21781 ttcacgcttt tgcacatgga gccgatttac tgacagaggt ggtttgtcat ccagactttc
    21841 ctaaaaacag agttcatgaa gtatttgata tacttggcca actatttaaa agaatgtcga
    21901 ttcgctttac agatgatgag gattggcgtt tagcaagagt gatctatgaa cctattttac
    21961 aagggaagtt ggagcaagaa caagtagctt cttggataaa aactgttgat tttccgatag
    22021 aagaaaggga ggatttttac aaattttcca actttagatc ctgtctggtg gaagtctatg
    22081 tccaacttga ccagagaaat agtttacaag atgagttgaa agaagctatc cagtcttttc
    22141 aatactagag attagctaat agttctatga ttttcaaaaa atttccaatc aattttcttg
    22201 aaaccctttc ctacttttga tagactagta tctagttttt gaaaaaagga gaaagaaaat
    22261 gaaaaaattt gttgctgagt taatcggtac gttcatgctt gtgttcgttg ggacaggagc
    22321 tgttgttttt ggaaatggtc ttgatggcct tggtcacctt ggaatcgcct ttgcctttgg
    22381 tttggcaatc gtggtggcag cctactcaat cggaactgtt tcaggtgctc acttgaaccc
    22441 ggctgtttcg attgctatgt ttgtaaacaa acgtttgtca tcttcagaac ttgtaaacta
    22501 catccttggt caggttgttg gagctttcat cgcttctggc gctgtcttct tcctcttggc
    22561 taactcaggt atgtcaactg ctagtcttgg tgaaaatgcc ttggcaaacg gtgtcactgt
    22621 ctttggtggt ttcttgtttg aagtcatcgc aactttcttg tttgtattgg ttatcatgac
    22681 tgtgacttca gaaagcaagg gcaatggcgc gattgctggt ttggtaatcg gtttgtcatt
    22741 gatggcgatg attcttgtcg gattgaagat tactggactt tcagtaaacc cagctcgtag
    22801 cttggcacca gctgtcttgg taggcggcgc agcccttcaa caagtttgga ttttcatcct
    22861 tgcaccaatc gctggtggag ttcttgcagc ccttgttgca aaaaatttcc ttggaacaga
    22921 agaataattg aaactcaaaa agccttgctc ctcatcttga ggaacagggc tttttcgtat
    22981 gatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtatggttac
    23041 tgacttcgtc agttctatcc
//
LOCUS       DAVLBN010000033        22933 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLBN010000033 DAVLBN010000000
VERSION     DAVLBN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.033"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..942)
                     /locus_tag="VXC24_001273"
     CDS             complement(<1..942)
                     /locus_tag="VXC24_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0493386.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEEGPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFL"
     gene            1190..1615
                     /locus_tag="VXC24_001274"
     CDS             1190..1615
                     /locus_tag="VXC24_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0493387.1"
                     /translation="MELSIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPEL
                     ADAMLAAKITGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            1616..2029
                     /locus_tag="VXC24_001275"
     CDS             1616..2029
                     /locus_tag="VXC24_001275"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV0493388.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            1975..2301
                     /locus_tag="VXC24_001276"
     CDS             1975..2301
                     /locus_tag="VXC24_001276"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493389.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(2668..2928)
                     /locus_tag="VXC24_001277"
                     /pseudo
     CDS             complement(2668..2928)
                     /locus_tag="VXC24_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(2931..3431)
                     /locus_tag="VXC24_001278"
     CDS             complement(2931..3431)
                     /locus_tag="VXC24_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493390.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            3467..3646
                     /locus_tag="VXC24_001279"
     CDS             3467..3646
                     /locus_tag="VXC24_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493391.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(3624..4592)
                     /locus_tag="VXC24_001280"
     CDS             complement(3624..4592)
                     /locus_tag="VXC24_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0493392.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(4678..4893)
                     /locus_tag="VXC24_001281"
     CDS             complement(4678..4893)
                     /locus_tag="VXC24_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0493393.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(4902..5756)
                     /gene="cvfB"
                     /locus_tag="VXC24_001282"
     CDS             complement(4902..5756)
                     /gene="cvfB"
                     /locus_tag="VXC24_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0493394.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(5816..6373)
                     /gene="frr"
                     /locus_tag="VXC24_001283"
     CDS             complement(5816..6373)
                     /gene="frr"
                     /locus_tag="VXC24_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0493395.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(6382..7119)
                     /locus_tag="VXC24_001284"
     CDS             complement(6382..7119)
                     /locus_tag="VXC24_001284"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0493396.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(7203..8537)
                     /gene="trmFO"
                     /locus_tag="VXC24_001285"
     CDS             complement(7203..8537)
                     /gene="trmFO"
                     /locus_tag="VXC24_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0493397.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(8832..9086)
                     /locus_tag="VXC24_001286"
     CDS             complement(8832..9086)
                     /locus_tag="VXC24_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0493398.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            9081..9885
                     /locus_tag="VXC24_001287"
     CDS             join(9081..9449,9451..9885)
                     /locus_tag="VXC24_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0493399.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(9874..10520)
                     /locus_tag="VXC24_001288"
                     /pseudo
     CDS             complement(9874..10520)
                     /locus_tag="VXC24_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(10629..11147)
                     /locus_tag="VXC24_001289"
     CDS             complement(10629..11147)
                     /locus_tag="VXC24_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0493400.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(11374..12243)
                     /gene="rsmI"
                     /locus_tag="VXC24_001290"
     CDS             complement(11374..12243)
                     /gene="rsmI"
                     /locus_tag="VXC24_001290"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0493401.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(12246..12563)
                     /gene="yabA"
                     /locus_tag="VXC24_001291"
     CDS             complement(12246..12563)
                     /gene="yabA"
                     /locus_tag="VXC24_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0493402.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(12603..13493)
                     /locus_tag="VXC24_001292"
     CDS             complement(12603..13493)
                     /locus_tag="VXC24_001292"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0493403.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(13490..14128)
                     /locus_tag="VXC24_001293"
     CDS             complement(13490..14128)
                     /locus_tag="VXC24_001293"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0493404.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(14348..15145)
                     /gene="proC"
                     /locus_tag="VXC24_001294"
     CDS             complement(14348..15145)
                     /gene="proC"
                     /locus_tag="VXC24_001294"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0493405.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(15149..16411)
                     /locus_tag="VXC24_001295"
     CDS             complement(15149..16411)
                     /locus_tag="VXC24_001295"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0493406.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(16421..17551)
                     /locus_tag="VXC24_001296"
     CDS             complement(16421..17551)
                     /locus_tag="VXC24_001296"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0493407.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(17631..19514)
                     /gene="cbpE"
                     /locus_tag="VXC24_001297"
                     /gene_synonym="pce"
     CDS             complement(17631..19514)
                     /gene="cbpE"
                     /locus_tag="VXC24_001297"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0493408.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(19517..20404)
                     /locus_tag="VXC24_001298"
     CDS             complement(19517..20404)
                     /locus_tag="VXC24_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0493409.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(20394..20855)
                     /locus_tag="VXC24_001299"
     CDS             complement(20394..20855)
                     /locus_tag="VXC24_001299"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0493410.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(20852..21760)
                     /locus_tag="VXC24_001300"
     CDS             complement(20852..21760)
                     /locus_tag="VXC24_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0493411.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            21753..21950
                     /locus_tag="VXC24_001301"
                     /pseudo
     CDS             21753..21950
                     /locus_tag="VXC24_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(22002..22673)
                     /locus_tag="VXC24_001302"
     CDS             complement(22002..22673)
                     /locus_tag="VXC24_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0493412.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(22727..>22933)
                     /locus_tag="VXC24_001303"
     CDS             complement(22727..>22933)
                     /locus_tag="VXC24_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493413.1"
                     /translation="KNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLPVHGFC
                     PRGTYDLGYIGGGNHLCKGSAARF"
BASE COUNT         6586 a         5282 c         4113 g         6952 t
ORIGIN      
        1 aagaaattca cttggcgact tgtagtccaa gcatttttta gggtagttgt taatccaatt
       61 ttcgataaaa gctacttctt tcggagtcgt tttcttggtt cctttaggta accatctccg
      121 aattaatcga ttatgatttt catttgaacc tctctcccat gaagagtaag catgtgcgta
      181 gtagatatgt tcctcaggaa atacctcaga caatcgtttg aactccgaac cattatctgc
      241 agtaatggac agaatacgat gctcccctaa tagtaacgta agcgcctgat tgacagattc
      301 agcagtttta tttggaatta accttataat ttggtgtctg ctccgccggt cggttaagac
      361 taacaggcaa taatttttta tcttagtcag taggacggta tcaatttcat aatgaccatt
      421 ttccaagcga agattaataa cgtcaggacc ttcttcgata gatttacctg ccggcttaaa
      481 gttcggacta gcttgcttct tgacaccttt cctttttctg ggataaagca tgtcggcctt
      541 cgtcaatcct aaatgaccat tatgaaacca gtagtagatg gttgaaatac caactttcac
      601 ttgcttcttg ttaaccatca tttcaggcga aaatttttgc ttatgatagt gtaagatctt
      661 ctctctgatt tcctttgtta aaattaactt tttcaccgac cgttttcgat tgaattggta
      721 aacagtttgt gcgtaatcgg cagaatagac ctttttgtat agcccttttc tcacttgttg
      781 taaagttgta cctcttttga cttcattatg aatcgtttga ggcgcctttc ctaacaagcc
      841 tgcaatttca cgattggact tattttcatt cttccaccgc tcaatcaagc gacggttatc
      901 tattgtcaaa tgtttccctt ttggggtata atgttcttgc atctctgtgc ctttccttgt
      961 gtttgtggtg aacaacaagt atagcacaga ggtgttttct tataccttaa atcacatttc
     1021 atttgacaac aggaaccctt gaacctgttt tttcagctaa accaaggcta tgattagcct
     1081 tggccaccta gcctaacagt ttcaaacctg ttatcaaatg aaatcatcaa cttactcaaa
     1141 catagtgaaa catctaattc ttgactaagg taaggtggct aacttcatta tagaactttc
     1201 aatcccaaaa gaaattaaaa ataacgaaaa ccgtgtcgcc ctcacacctg caggtgttca
     1261 tagcttagtt agtcgtggtc atcgtgtcct tatcgaaaca aatgctggtc tcggttctgg
     1321 ctttactgat gctgactatc aaaagcaagg agctgagatt gtcgctactg ctggtgaagc
     1381 ttgggcagca gagttggttg tgaaagtaaa agaaccttta agttctgaat acggttactt
     1441 gcgcgacgtt cttcttctct tcacctactt gcacatggcc gctgctccag aattagcaga
     1501 tgctatgtta gcagcaaaaa taacaggaat tgcctatgaa actgttcgtg acaatcaagg
     1561 acaactaccg ctcctcgttc ctatgagtga ggttgcaggt cgtatggctg tttaaatcgg
     1621 agctcacttc cttactaagc aagctggtgg ctctggtgtt ctacctggtg gtgtaccagg
     1681 tgttccaaaa ggaaaagtaa ctatcatcgg tggtggtgtc gtcggtacac atgctgcccg
     1741 catcgccctt ggtcttggtg ctcaagtgac tattttagat attagtgcca agcgtctctc
     1801 agttctagaa gaagtctttg gaagtcaaat tcaaactctt atatctaatt cattcaacat
     1861 tgaagcaagt atgagagatg ctgatgtggt gattggagcc attctcatcc ctggtgcaaa
     1921 agcaccggaa ttggtgacag atgagatggt caaacaaatg cgtccaggct ctgtatcgtt
     1981 gacgttgctg ttgaccaagg tggcgttatc gaaacagctg accgtgtgac aacgcacgat
     2041 gaacccgtct atgaaaaaca cggtgttctc cactatgccg ttgccaatat ccctggtgcg
     2101 gttgctcgca cttcaaccat cgccctaacc aatgtcactc ttccttatat cgaagctttg
     2161 gctggcaaag gattcgcaca agcaatctct gaagatgaag gcttgcgtca aggtgtgacc
     2221 acttatcaag gttacttgac tagcctacca gttgctcaag gacttaatcg tgactacact
     2281 gatatcaatg atttagtata aattttgaaa agaaaagggt gacttcgcaa gtcctaccca
     2341 ctgtgctttg tgtcatcagc tattacatcg ttggtttatt gtactgtata ctttgcaact
     2401 ggagactttc gttccagact caattgtgca taagaaactc taaattgaat aaagtcaaca
     2461 gagtttcgcc caaccacttc gtcttgtaat gacaattata taaaccaaag gaagctgagc
     2521 tctttagtcc cagcttcttt ttatatataa aattttaccc gtgcaaagac agggccttag
     2581 cagacttctt ttttacttcg ttcacccttg ctttttcttt ttaggtttgg gcgttggcag
     2641 ttggttatac atagctaaaa tcaggtctta tagaaacatc ttattatcaa gttcttccac
     2701 tcaaatcatt tctttggcac ctttgtatgg aaactcaaaa aaagattggt caatcttatc
     2761 taagactgct tgcacgggtt taactaaaaa gcgatcatca taaatgccgc caataatctt
     2821 gccgcggaag taaagaatat actcccccat catggaacgg taagtcacat catctaatcc
     2881 tgataattgt tccaaaacaa attccaaata gttcttactt gatgccattt ctaatcttct
     2941 aggctctgtt cagcgataac aaccgtatag agttcttgct taacctcgca tccaattgat
     3001 ttaaagccct gcttttccca aaaatgctga gattgcggat ttcccttaac ataagccaaa
     3061 cgtgcctttc gaaagttctt agcaaaataa gctagtgctt ctgtcacaat atgactacca
     3121 atccctttcc tctgataggc ttgatcaacc ataaacaaac caataaaaac agtctcctca
     3181 tcaggatgtg catagacaaa atctataaca gccacaaggt cagatccatt ccaaaatcca
     3241 acaaaaaact tatcagcctt agctttacct tcaggtagac aaagcatgtc ctcttttaca
     3301 gttgcaaaat ttggctctgg tggacaatgc tgaaaataca gaggattact ttcatataaa
     3361 gataaaatac ttggaatatc cttttcagtt agtatcctac aactgtaata cttagatagt
     3421 tggtcaatca tcttttcaaa ttcctacttt cttgtgccct gtgattatga cacaggaaga
     3481 tgcactgatc gtcatcagcc acataaaagt tctttccatc gtgcctaatc gttgtctcaa
     3541 acctttggat aaaaccttta gcctatacaa ctggattttc ctctctcaaa agtatattct
     3601 tttgcaggca aacttcctca aaatcagtcg tgtgcaactt cagtagaata ttcataggct
     3661 cggataatct gagcgacaac tggatggcga accacatcct tggctgaaaa atgaacaaag
     3721 tcaatctgat ggatgttctt gagtttctct tgagcatcaa tcaaaccgga cttgacatta
     3781 cgtggcaggt caatctgact aatatctcca ttgacaatca tcttagaatg aaaacctaaa
     3841 cgagtcaaga acatcttcat ctgcatgatg gtcgtatttt gcgcctcatc gagaatgaca
     3901 aaggcatcat ccaaggtccg tccacgcata taggcaaggg gcgcaatctc gataatttca
     3961 cgctccatga gtcgagttgt ttggtctttc cccagaatct gatacaaggc atcgtaaaca
     4021 ggacgaaggt aaggatccac cttctcctta agatcacccg gaagaaatcc aagactctct
     4081 cccgcttcca ccgctggacg agttaggata attcgcttga cttgcccacg tttaagggca
     4141 gtcactgcca aggtcactgc aaggaaggtc ttccctgtac ctgctggccc aattccaaag
     4201 gtcacatcat gctgtttgac actgtccaca taaagctttt gccctagggt tttgacacgg
     4261 ataggtttcc cagtattatc tttgataatt tcttcttcgt aaagggcgac aaacttgtca
     4321 atttcatcat ttttgaccat gctaatcgca gtgactacat ctggcgtacc aacggtcatc
     4381 ccacgattta ccaagaccat caaagcctga ataacttgac gggcttcctc acaggcagac
     4441 tcttctccca aaacctggac aatctccgta cgagcatgaa tcacaacatc aagctcttct
     4501 tccatcaaac gaagatggcg ttcattggaa ccaaaaagat gaaacaggtc atctggatga
     4561 ctcagttgaa tgtctattga atgttccttc aaataaagaa cctctctaat ccttttattt
     4621 ctttttatta tagcagaggg atggagaaat tactagccca aacccaatga ataaatgcta
     4681 gtgttctaga tattcctgcc aaatgctgtc aaaatctcct aggttaaaag agaaactggc
     4741 atgctcctcc aaaaagcgac tgacctcatc aaaatcatct gtatgttttg gaaaagctgc
     4801 ctcttcaaaa gcgaggtctg ccaaaattgc tttgggactg ttacttttag gattgcgctc
     4861 ggtcatgagc caagtgtaaa atgattttct cataagcctc cctaaatcaa ctctgtccca
     4921 aactggtcct gcttgatttt accagccttc ataagaccac ctaaagcttt cttgaactga
     4981 cctttagaaa tgccaaaggt tgccttgatg tcgtctggag atgacttatc atttaaggtc
     5041 atgaaaccgc cattactttc caaataagtc aaaatcatct gagcatcgtt ttccaacatt
     5101 tcaaaggagc gtggtttgag ggagaggttc agagtgcggt ccacttcacg gaaaccaata
     5161 acgcgcgcat ctaatacttg ccccaaacgt ggctctgcgt aacgctcgct aggatgaata
     5221 aaaccaagca tattattttc tggtaggtaa acaaaagttc ctgacagctt gagacggtaa
     5281 acaatggctg gccagttttg gttctgcatg ttgttgtagg caggacgagc aagacgttgg
     5341 aagtcttctt gataagccaa gaggccccag atacggtctt tcttatccac ttcaagacgg
     5401 atgtagagtt ggtcgccctt cttaggccag agttccttga gctcagggag aatatcgagt
     5461 gacacaacga tttccttgtc aggaaggcct gtatctacaa agacacccaa gtccttacga
     5521 acctctgtga cacatcccca accaaattgg tcctgagtgg cagtcacttc taaggttgtc
     5581 aggcggagtt tttgcttcat atccgtgtat gcaaaacctt tgaccgtatc ccctactgta
     5641 tgttggccct cttccttagc aagagcatag gtttgaccat ccttttgcac aaagtaaaaa
     5701 cggtcatttt catcgatgat cagtccaacg ataaaacttg caagatttgt attcatattt
     5761 ccttctttcg aataaaactc agccagcaat gccaactgag tttttctgtt tatttttaga
     5821 cttccaaaag ttctttctct ttgttagcag tcatgtcgtc gatgtgttta acagcatcgt
     5881 ctgttacttt ttgaatatct ttttcaagag tcttcaattc gtcttcagtg atttcttttg
     5941 ctttttcttg tttcttagct tcgtccatag catcgcgacg gatattgcgg acagccactt
     6001 tagcattttc gccgaccttc ttcacttctt tagcaaggtc acgacgagtt tcttctgtaa
     6061 gagctgggat aaccaagcga atcacagaac cgtcattagc cggtgtgata ccaagatcag
     6121 aagcgttcaa ggcacgttcg atgtctttca atgaagactt gtcaaatggt gttaccaaca
     6181 aaacacgcgc ttctggaatc gtaattgaag cgatttggtt aagaggagtt tcgactccat
     6241 agtattctac atgtacacgg tcaagcaagc ttgcattggc acgaccagca cggataccac
     6301 caaattcacg agcaagtgat tggtgagatt gggtcattct ctctttagct ttttcaataa
     6361 ttacgttagc catattcttt cttattcctt ttcttcgata ttatttgaaa ctgttgttcc
     6421 gatattttca ccaaatacga cacgtttgat gttgcctgat tggttcatgt tgaagacaac
     6481 caagtcaatg tcgttgtcca ttgagagggt tgaggctgtt gagtccatga tacgaagacc
     6541 tttgttgata acatcacggt gggtcaattc ttcaaactta acggctgtct tgtccttctt
     6601 aggatcggca ttgtacacac catcgacgcc atttttagcc atgaggatgg catctgcttc
     6661 gatttcagct gcacgaaggg ccgctgttgt atctgtcgag aagtatggtg aaccaattcc
     6721 agcaccaaag ataacgatac ggcctttttc aaggtgacga agggcacgtc cacggacata
     6781 aggctctgcc acttgttgca tagcaatagc tgtttgtaca cgcgtatcaa ccccaacttg
     6841 ttgcaatgaa tctgccatca caagagcatt cataacagtc ccaagcattc cagtgtaatc
     6901 tgcctgaaca cggtccatac ctgcttctgc tgcaggttct ccacgccaaa gatttcctcc
     6961 accaataaca agggcaattt cgatacctaa gctatgaact tcttgaatct cttttgcgat
     7021 tgtttgaact gtttggatat caatccctac gccacgttca ccggcaaggg cttcacctga
     7081 taacttgatt aaaatacgtt tatacttggg attcgccatt ttcactctcc ttctttcatc
     7141 ctacctattt tatcacaatt tctaagattt ttatagtatc atgagcaatt ctttcaaaaa
     7201 aattagacag tcaaaaattc ctctaagtcg gcaagggcac gctctgcaat tttttcataa
     7261 cgagccttct tatcacggat acgctcgcct tccaactcct tgatgatccc aaaattgaca
     7321 ttcattggtt ggaaatgttt gctgtcggca tgggtaatgt aatgagctaa gcttccaatc
     7381 gctgtcgtct cggggaaaat aacctcgctt tcttccttga agagacgagc tgcgttaatt
     7441 cccgcaacta agcccgaagc cgccgactca acatagcctt ccacccccgt catctgacca
     7501 gcaaagaaga gatttggttg tttcttggaa cggtaagtct gctcaagaag atttggtgaa
     7561 tccatgtaag aattgcgatg catgacacca taacggacaa actccgcatt ttcaagaccc
     7621 ggaatcattt ggaagacacg cttttgttct ccccatttga ggtgggtctg gaaaccaaca
     7681 atattgtaga ggctaccagc tgcattatcc tgacgaagtt gcacaaccgc ataaggtgtt
     7741 ttaaattctc catcacgagg tcctgtgtag tcgtccggat actcaagacc gactggcttc
     7801 atagggccat aaagcatagt tttaatgcca cgtttggcca taacttcgat tggcatacat
     7861 ccttcaaagt acttttcttt ttcaaaagaa ttgagcggtg cttcttccgc attgaccaag
     7921 gcttcatgga aatccataaa ctcttgcttg gtcattggag cattgagata ggctgcttct
     7981 cccttatcat aacgagattt gagatagacc ttactcatat cgatagtgtt gacatcgata
     8041 ataggcgctg ctgcatcgta gaaatagaag ccatcgccat tattaagggc atgaatcttt
     8101 tcagccaggg catcgctagt caagggacca gtcgccacaa ctgtaataac atctgttggc
     8161 aattctgtaa tttcatcacg caccacttca atcaaggggt ggttgaccac tttttcggtc
     8221 accatttgag agaaaccatc acgatccacc gcaagggctc caccggcagg aacacgtgta
     8281 gcctcagcag attccaagat aacagaaccc aagcgacgca tttcttcctt gagaagacca
     8341 actgcatttg tcaaagcatc cccacgcaaa gaattggaac aaaccaactc agcaaaattg
     8401 tctgttttgt gctgaggagt cgacttgaca ccacgcattt cataaagttt aactggaata
     8461 ccacgctctg cgatttggta ggctgcttca gaacctgcca aaccagcacc gataacattg
     8521 atataagatt gagacacgac actaatacct ctttgggagt gtgaagttaa gattcacatt
     8581 gaaaaagcca atcagactta cgagatttcg agtttcttgg ctcaggctga aaaagtcccc
     8641 cagactttcc tcgctctcga atttcttggc tcaagctgaa aaagtccccc ggactttttc
     8701 actcccacaa atctttctat ttttttcttc tactagtata acaaaaaaag ggaagaaggc
     8761 aaacttccct gtttagtcat tttcttgatg taaagagata gagagtattc cagttaagaa
     8821 tcaattatat gctactctat aaaatctttt ccacataacg gatcgatagg gactgttatt
     8881 ctatctcttg ctataaccgt attatctaaa acagcataac attcaacata gtgatctcct
     8941 ttaaactgtg aatcttcgtg atattttatt ttacctgaaa aaatagcacc acgctcacaa
     9001 tttcttctaa tagcctcagc ttcaatattt cttactttcc aatagacttc ctgcgaaaca
     9061 aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcacgat
     9121 ttaagcgtct tgttggtgtt cagcgcacga cttttgaaga gatattagct gtattaaaaa
     9181 cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc
     9241 ttcttatggc cactcttcaa tatgtgcgag aatatcgaac ttatgaacaa attgcggctg
     9301 attttggtat tcacgaaagc aacttaatcc gtcggagcca atgggttgaa gtaactcttg
     9361 ttcaaagtgg tgttacgatt tcaagaactc ctctcagttc tgaggacacg gtaatgattg
     9421 atgcgacgga agtaaaaatc aatcgcccta aaaaaacaat tagcgaatca ttctggtaaa
     9481 aagaaatttc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct
     9541 ttggatatcg ctgtgaacta ttgtcgtgat atgaagttgt tcaaaatgag tcgcagaaat
     9601 atcggacaag ctggtaaaat cttgtctgac agtggttatc aagggctcat gaagatatat
     9661 cctcaagtac aaactccacg taaatccagc aaactcaagc cgctaacagc tgaagataaa
     9721 gcctgtaacc atgcgctatc caaggagaga agcaagattg agaacatctt tgccaaagta
     9781 aaaacgttta aaatgttttc aacaatctat cgaaatcatc gtaaacgctt cggattacga
     9841 atgaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct
     9901 aatgtaattc tcaagctgtg agttcattat gatttgtaaa tccgatatat cttcagcagc
     9961 taaaaacaca ttttgaaatg ttccaagtcc gttttcacca aaactatatt ctctcttact
    10021 atacttactc ttattattct ctatatagtt agagtcaagg ttcttaacct cttgaagttc
    10081 attttcttta cttctgaggt taaaatcttt tacttctgaa gttaagtttt ttgacttctg
    10141 taagtcattt tcttttacct gaaatatact cataaagtct ttaacataaa tgatgttcgg
    10201 cttaccaagt ccaagcctta ctctttcgat cagtcctatt ccttttttac atcaagctca
    10261 tctaatgttt ttatggcagt tggctttgag atatttcttc ttttcataat ttcttcgaca
    10321 gtaaaataga taaatactct gccttccttg tctatccagt tattcttaaa tgacattcct
    10381 gtctgtttaa gaagtatgga ataaaggata attgcttctg ctgataagcc ccgaaattct
    10441 tctctatcaa ctaatatctc cggtactttt aagaagttaa atctttccgc ttctctgtta
    10501 taaaaatatt caaagtccat gcaagatcac ctcccttctt aaaaatttgc aaagaaaaag
    10561 acgatagttt ttcttctatc gcctttggta accattttta tgaaattttt taaagttaaa
    10621 aatataattt ataatactat cttcttccat tttctgattt tagttctgaa agttccaaaa
    10681 ggtgcaaccg tatttacatg aataaactta tacacttccc aagtcgctgt tttagtcgct
    10741 tcatcagccc actttctcat atgcggttca aataattctt cctcactcaa cgaatcaatc
    10801 attgcagaga tagaattaat attttcattt aattttgctt tcaactcttg cagagataaa
    10861 tgagcgtagg tatctgtgaa ccactgatat aattcaccaa gttgattcca tttaaattta
    10921 tccgatggtg tttttacttg aagccccttt ctttcatctt cttcccattt aagaaccaag
    10981 ttggtccaac caacctgata agcaaggttt tctgctggag ttctgtcaac ttcatcagct
    11041 ctcttatctt ttaaattttc tggaatatta tcaaattcta aaatatattt ctcaaatgtt
    11101 ttctctatct cagcttttag ttcttcttta ttttcgtatg ttcgcaaaaa atcaccttct
    11161 ttctgattta tcaatccttt gatttaaaat gaccttattt ttctatttat accttctaag
    11221 aacgctataa ctgctgctcc aaccatcggt attccgtatg ggcttaataa aaaacttaat
    11281 accaaagctt ctataccaag tgatacatct ttatattatc atcactaatt aagttaaaca
    11341 gaaacagaca gaattattac atcctgtctc cctttattgt ttttcttccc agtcgtggta
    11401 ggcagcgtag agctgacttt tattccactg gtaaatctta gcgacttcct tgatagcttg
    11461 gtttttcttc acaccttgct ggatgcgggt ttgaatttct acgaacaagt cttcctcgtc
    11521 cttttcctcc acaccctgac tggcaccctc aacaatgaga agacattcgc ccttgagtgg
    11581 cgtttcagca atgctttcta ataactcaga gatagtacct cgttggtatt cttcatagat
    11641 tttggtcaat tccctgacca agacaacgga gcggtcaccg tagacttcta acatattttc
    11701 caacgtgtct gctacacgat gaggtgattc ataaaaaatc tgtgtttcag gataatcttt
    11761 tttcaagcca aaaaattgct tctgctgacc tgattttctc ggtaaaaaac cgtaaaagat
    11821 atgtggctgt ggcgctaaac cactggcaat caaggcagaa attcctgcag aggcacctgg
    11881 aactgtcaca actgcaattt cttcctcaat agctgcctta actaaatcat gaccagggtc
    11941 tgaaatgcta ggcaaaccgg catcagagac ctgagcaata ctttgccctg ctttcaagaa
    12001 accaatcaaa tcaggaattt tttccttggc attgtgctca tgaaaactga tctgcttggt
    12061 ggaaatgtca aaatgcttga gcaaaagccc tgtattgcgc gtatcctcag cagcaatcca
    12121 gtccacttct ttcaaggtct ggatagcacg aaaagtcata tcatctagat tgccaatcgg
    12181 cgttgccact agatacagct tgccataggg agactgcccc ttaaaacttt tttgaatttg
    12241 catgcttact ccctgtataa caactcatca cagaacatac attcttcgtc ctgctctcga
    12301 cgttgtccat aaaaatcatt acatacgtga aatccatcac ggtaaatacg acggacactt
    12361 tcgcgaacat gcttggcctt gacgggagcg tctgcttcca cctcacccaa gcgttctcgc
    12421 aacttactat tttccaagcg aagagctgta ttttcttcta ccaagctctt gagatttttc
    12481 ttgatggctt ccacatcggc taaggttacc aataattgtt gggaaaaatc atccagcgcg
    12541 tcaaataatt cttttttgtc cataaaacag ccctttcctt tctttatcat tcatttttga
    12601 gtttatattt ctttcaagac cagatattcc atggcatttt gaaagctgac attagcttgc
    12661 cacatttttc tagcttctag taaatcttgt agaatcactc ttactcttac ctgcaagagg
    12721 tcctgcccac agagaacttc aagaatccgt aaaacctgat cctgtttttc cttatcatct
    12781 gccaagttgg ctaatttggc aacctgtaga taactttctt ttttcttagc tactaaccaa
    12841 gtcagcaggc gttcactttc atcgaccaag gtccaaaaac ttgcctgatt agccaacttt
    12901 tctgcttcag ctcgcgattg actaaactta gctaaaagag tcgctttttt cttaacaagt
    12961 cccatttgtt ctaagagtaa gataagtttt tcttcttgct ttttaaagtg gaagatctga
    13021 gtccgacttc ggattgtcgg taacatcttt tcctcatcgc tagtcaagaa gaaaatataa
    13081 acttcactct ggggttcttc gatgaccttg agcagagaat tggctgcgtt gggatgcatt
    13141 ttatccgctt gctcgataat aaagacctgt tgctggcttt caatccctgc ttgagaaaac
    13201 tgtcccacca attcccgaat gcgttctgtc ttgatgacct gattgactgg cttaatcaag
    13261 gtgacatctg gaaactcttc ctgttcaatc agcttgcaac ttcggcattt ctcacatggt
    13321 aagacgccaa ctttatccgt acaaaagagg ctcttagcta aaaattgcgc catttccaag
    13381 cttccaaaga aacctgaaaa gagataggcg tgattgagct ggtcttgttc taagatacgg
    13441 acaaaacggt caaactgagc tggttgccaa gcctttagtt gatcttgttt catttggcca
    13501 agtccattcc gtcaaacaag acagccttgg tagtttccac aacttgctcc aaagggagac
    13561 tagcatcaat cttgacaatg cgatttcctt ctttttccag gagagaaagg tagccttgac
    13621 ggactttctt gtgcaattcc aaaccttcca agtccagacg attgacctcg cggtcactat
    13681 tcgcagcaat gcgagccagc ccttcttcca cctcgatgtc aaaatagagt gtcaaatcgg
    13741 gtttgaggcc atctgtcgca aactgattga gccagtcaat ggcttcaata tctaagccac
    13801 gaccaaatcc ctgataggca acagaactat cgataaaacg atccatgatg accaacttgc
    13861 cagcttcaag ggctggaaga actttttcca ccaaatgctg tctgcgactg gcaatataga
    13921 gaagtagctc tgttttagca tccatctgag tatgacttgg atccaaaatc acttcccgaa
    13981 tcttctcccc aatcaagact ccgccaggtt cacgggtcgt cagcaccttt actccttttt
    14041 cctctaaaat tggtagcaga gcctctaaaa cactggtctt gcctgctccc tctggtccct
    14101 caagagagac taaaaatcct tttgacatgt ctaactcatt tcttttttac tacttctatt
    14161 ctatcaaaaa aataggggtt tgtgacaatc tttttgtctt ctcatttcat actcaatgaa
    14221 aatcaaagag caaactagga agctagccgc aggctgtact tgagtacggc aaggtgaagc
    14281 tgacgcagtt tgaatttgat tttcgaagag tatcaaccac cataaaagag gcagataaaa
    14341 ctacctctta tttacctagt tcttgtgttc gtttgtaggc ttgatgaact gcatccatga
    14401 ctgttcctcg gaaagcatgc gcttctaggc ttgctacacc agcgatagtc gaaccgcctg
    14461 ggctacagac ttggtctttc aatactccag gatgttgctg actttcaagg accaattgcc
    14521 cagctcctac cacagtttgt gctgccattt tcaatgctat ttctcgtggt aatcctgtct
    14581 gaacacctgc atctgccaag gcctcgataa aaagatagac aaaggctggt ccacaacctg
    14641 caagacctgt cgctgcatcg attaaacttt ctcctagttc aaccaagaga ccagccttgg
    14701 ctaaaagctg ataaaagagc tcactgtcct cagccctgca attaggagac aaggcataac
    14761 taatcactcc ttgcccgata gaagcagggg tattaggcat catacgaata attcggtgtt
    14821 gacttgggat aagacttgct agtttttcta aggtcaatcc agctgccatc gaaatcaaaa
    14881 gaagactttc tcttttttca aggatggtct ggtattgaga aagcagttca gaaaactgag
    14941 caggcttaac tcctagaaaa atcacatctg cttctgcaaa catttcttca ttgctggaag
    15001 cctgaccacc aaagtctgca atgaaagcat ctaccttagc ttgactacga ttggcaagga
    15061 gaatctcatc tgacgtccta gtctgcaaga cagattttgc caagctagca cccatattcc
    15121 ccaaaccgat aaatccaatc ttcatctctt actcccttat ctgcccatca ccggcaacca
    15181 catacttgta gctggtcaac tctttcaagc ccatgggacc acgcgcgtgc aatttctgag
    15241 tagaaatccc catttcacaa ccaagaccaa attgtcctcc atctgtgaaa cgagttgagg
    15301 cattaacata caccgctgca gagtccactt gatctgtaaa gtatgctgca gcttcagcat
    15361 tttccgtcac aatagcatcc gaatgatggg tgctgtggga ttcaatgtgc gcaaccgctt
    15421 cttctaaact gctcacaacc ttaacagcaa ggacatagtc taaaaactcg gtgtcaaagt
    15481 cttgggtctc agctgcttga cctgaaacaa actggcttgc tttgctatcc aagcggaatt
    15541 gaattggttc cagtccagct tccttacgct ctgcaaccag catttgatcc aagcgaggaa
    15601 ggatgcttgc tgccttgttt tcatgaacca gcagaacctc catggcatta caaacagaag
    15661 gacgactggt tttagcattg ttgatgatag acagcgcctt gtcttcgtct gcatccttat
    15721 ccacatagac atggacaatc ccagtccctg tctcgataac aggtacaatc gcattctcaa
    15781 ccactgcatt gatcaagcca gctcctccac gaggaatgag aaggtctaga tagcccttgg
    15841 ccttcatcat agcataacta ctttcacggc tagtatcctc caccagttga atcacatttg
    15901 gatgaatagt agtcgtctcc aagcccttct tcaaggctgt gacaatggca tgggttgttt
    15961 gataggcatc cttaccacta cgaagaacaa ccgcatttcc actcttaaga gtcaaagcag
    16021 ccgcatcaga cgtcacattt ggacggcttt catagataat accgatgaca cctatagcta
    16081 cacgtttttt tgtgataacc aaaccatttt caagctgact tgtttctaaa acttcaccga
    16141 ttggatctgg taaggcaacc acttcacgaa ttcctcttgc catcgcttct atacgatctg
    16201 catccaaata aagacgatcc aacatcacat ctgagatttt ccccttagcc gctgccatat
    16261 cgagggcatt agccgctaaa atttcctcag tagcagccac taagtgatca gccatggcta
    16321 gcaaggcttg gtttttcact tcttcactag ctgtgttaat cgatttttta acagcctgta
    16381 cctgttcaaa ttgttcttgt ctactcacca tagtttacct ctaaaattct gtaaaaagta
    16441 gttggatttc aggagtaatg gaaatccagt cgtcacggta aatcaagaca cccttggctt
    16501 tttgagaacg caacatatcc tccaaagcag atgctccaaa ttgcacgcgt ccttttccaa
    16561 gtgattttcc actttccttg tcaaatactg tcacgatatc accgtaagaa aaggctcctt
    16621 ctgcttcaac gataccagat aagagaagac tctttccatg ttgagagaga gcttccgcag
    16681 cccctttatc aacccaaata gaaccttgac tctgagcata gaaggcaagc cattgtttct
    16741 gggtacgaag ccccttctct tgagcaacaa agtaagaacc atcctcggtc tcctctgccg
    16801 cctcaatcat ggaatctgat ttcaaggatg agcagatata aacaggaact cctgattccg
    16861 tcgcgatagt tgcagccttg attttggtta acataccccc agttccgttt gacgaaccag
    16921 ctccaccagc catatcaata atctcacgat tgatggtctc gattctctcc aagcgtttgg
    16981 ctcttggatc tgaattagga tttccagtat agagaccgtc cacatctgtc aagaaaacta
    17041 aaaggtctgc ttggaccatc gccgctactt gagcacttag agtgtcattg tccccaacct
    17101 tgagctcatc aataacgaca ctatcattct cattgatgat aggaattgcc ccacggttga
    17161 gcaaaaccga caaagcctga tgggcatttt tataacgacg cttatccaca aagtcatctt
    17221 gggtcagcaa gatttgtgca gaaacgattt gacgcaagag aagattggtc gtatattctt
    17281 ccaacaaaag tccctgccct accgctgctg aagcctgttt atcagcaatt ttagtcggac
    17341 gctttttaaa tcctaaggct ccaaaaccag ccgcaatggc acctgaagac accaaaatca
    17401 actcatgacc agcctcgtgc agcatagcca actgctgggt aatatccttt accttactac
    17461 gtgataaact tccatcctca tttgtcagag aagaagtacc caccttaaag acaatccgtt
    17521 tgtatttcat agtctcactc cgattattca tatttatcca ttataacatg aataacagga
    17581 aatagaaaag agttgatagg aaaaagaagg ccctaaaacc ttcttttcta ctactgttct
    17641 gattccgatt tgtttacact cgtttcagag ctttgtgaag ttgaggatgt caaatcttga
    17701 ctagttgaaa aatttgtaac actttcatgt tgactcgttt ctttattttc aagatccttt
    17761 ttcactactt ctttggattc ttttatttct gaatgacttg tagttttaat tgtagcagat
    17821 ttctcgatcg aaacatccac taaccaggca ccacttgaat ccacagtata accttctggt
    17881 gtcttaccgt tcacaagtaa ttgaccattt tctttcaaga agtaccattt atccttgtcc
    17941 ttgatccaac ccacagctcg tgaaccgtct gtcttgtaga aataccaatc atttgccttt
    18001 ttatgccagc cttgcttcat agctcctgaa tcttccagat aataatgttg accagcaact
    18061 tctatctcac ctgtcttcat gacaccagta gaatccatat agtaccaggt ttctttatct
    18121 tttacccagc ccattttcat ttcccctgat ggagcaaagt aataccattg ccccatatat
    18181 tgaagccatc ctgtcttcat agaaccatca acatccaaat aataccactg ctctttatct
    18241 tgaatccaac caatttccat ctggttttct ttgttaaaat aataccagat tccagcgatt
    18301 ttcttccaat ttttagcaga agcaccagag tctgtcaaat agaaccaatg attgttccat
    18361 tttttccatt gattctgtaa caagataccc gtttggttaa agtaatacca ttcaccttcg
    18421 atttcattcc aaccgacagc atactctcct gtagaatcag gcgcttgata ccaccagttc
    18481 ccatatgcac tcttatgcca accagcttga aaacttggaa tcggcttgta ggatgttgaa
    18541 atattgacaa aaccgtcttt tcgaatatca aaaactgttg catcatagtc tttgctggct
    18601 gcgttgattc tctcaattcc tcgttctttg agccaattaa catactcact atcaacacca
    18661 tttttccaag gtagactatc cgaagtttga acaatcaaac tcggactcaa atttttaatg
    18721 aaatccttgg tatttgattt gttggtatca tggtgatgat taaacttcat caaatcaact
    18781 tttccaatga gaggaccata cttgtcttct gctccatgaa cattatctaa atcgccccca
    18841 aggtaaattt tcttgccatt gactttcacc acgctaatca aggaattgga attgtcatcc
    18901 caaattttct ttaattcacc cgatgaatca gtttcatttt cataattata gagctgaata
    18961 tccatgtccc caaactgaaa atgagcatcc ccttgtgtga tattttgaat aactgaaaca
    19021 cctttttctg cagcagtctg taaaacctta tcatagccat acagattatc ccatagacgt
    19081 tcagaattag taatacgact atcactatat ttcttaagat agactcggtc aactggatag
    19141 gtagacagta attcatcaac atttccaata tgatcactgt gggtatgggt caccaaaata
    19201 aaatcaagtt tttggacacc caattccttc aaacgacgaa agacacggtc tgttagaaca
    19261 tgcttataag acgtttcaat tccttctctc catggatagc gagaatcact tccatctggg
    19321 aaatcataat cttctcctgt atccaccatg gcaaaatgtc cattgctttc aagaataatc
    19381 gcatcactgc caccttcttg aacattgata aagtggattt tatttcctga actttcttga
    19441 gcctgaacat tcccatacca tgacaaacct aaaaaagcgc ctacaagtgc taaactagtt
    19501 aatttctttt tcattcttac tttctcaatc tctccaaggt ttccttaaaa atctctggga
    19561 tatctgcttt aaattccaag gtcttacctg ttctcggatg agtaaaacct aaagtcttgg
    19621 catgaagaaa ttgtccatgt cctttcaaag tcttgcgagg accatagacc tcatcaccag
    19681 cgactggatg gccgatataa gccatgtgga cacggatttg atgagtgcgc cctgtctcca
    19741 gttgcaactc tactaagcta taatcgccaa agcgttccaa gacgtgaaaa cgcgtcactg
    19801 caggcttccc tttagcagtt acagcctgtt tcttacggtc tttttcactc cggccaatcg
    19861 gcgcttcaat tacaccacga tcattaggta gatttccatg aacaatcgcc caatatttgc
    19921 ggagagactt tttatccttg agttcttggg caagtgctag atgcgcatca tcgtttttag
    19981 caatcatgag aagacctgac gtatccttat caatacggtg aacaatccct ggacgcagaa
    20041 ccccattgat acccgacaag tccttaatat gatacatgag ggcatttact agggttccac
    20101 tggtatgacc agcactcggg tgcacaacca ttccctgagg tttgttaacg acagccacat
    20161 cctcatcttg gtagactatt tctagcggaa gatcctcagc cacatactct aatacctctg
    20221 gttctggcac atggtaagtg acgacatcac cctcttggac tgtgtattta gctttcttga
    20281 cttgaccatt gaccaagacc tggcctgatt taatttgttc attcgcgaga ctacgtgata
    20341 attctgacaa atctgacaaa gccttatcca aacgcagacc accagtttca attttaattt
    20401 ccatttattt cctcttttag cattgcaatc aataaaataa tcactccaac cgtcagatag
    20461 ctatctgcca cattgaaaat tgcaaagttg ataaagtcaa ggtggaacat atccacaaca
    20521 aagccctgac tgaccctgtc aataaagttt ccaagaccac ccgcgattat tagagtcaaa
    20581 cccaagacca tccagaatga gtcctccatg tgtttatgta aataccaaat ggcacctatc
    20641 acgacaacca gagtaatgac agcgaataac aactgctgat cttgtaagat agaaaaggct
    20701 gcacctcgat tttgcaggta ggtcaagcta acgaaattgg ggatccagga gcgcacttca
    20761 cccagtggaa tctgctggac gatataggat ttgaccaact gatccagccc aatcaaaagc
    20821 agtacaatga ctgccactat tgctcttttt ttcatgattt cctcttttga tcaaaatatt
    20881 cttgcatgac ttctacgaag agagtcccag cttgactaag ctccacttct tcacgtttaa
    20941 catagaccat gcggttatct aggttatcct tgagacgaat aactgtaatg ccattaacac
    21001 tgtcactatc taaaaatcca gaacctgtcg cataggcgtc cgtccgctcc aaaataccat
    21061 tcaaggtggc acggtctgtc acattaaaca tctgtgagct agcgctggta tcaacaaagt
    21121 tctctgaata ataaaggtac tcgtctttct cttgagtgaa acgaaccgtt ggtaaatccg
    21181 ctaaatcctc catgactaat tcctctttct gggctaaagg atgaccctca cagagataaa
    21241 tatgggtatg gaaaggaatc aattcgatga cctccagacc taacttttca acccgttgca
    21301 taatcccctt tttattttga ttgttgaggt agataatccc aatctcacta tgcccttgcg
    21361 ccacttcatc taatatttga acagtagttg attcaaaaat acggaagttc ttatagtcag
    21421 gatagcgctc tgaaaaggcc gtaatagttg gtggtaagaa gtcatagtgc tggctagcaa
    21481 cggaaaattc atctttttct tcttcaggat tggcatactg attttgaaaa atatcaaatc
    21541 ctttaaccaa ttcttgcgct ttttcataaa attccatccc acgacgggtc aagaaagtcc
    21601 ctgagctggt ccgacggaaa atcttaaaac ccaactcttt ttccaaatcc cgaacagaaa
    21661 tagacagact cggctgacta acatacatct tttcagcagc ttcacgaaaa gtaccactat
    21721 tggcaatagc cacaacatag cgtaattgtt gaatgttcat cttctacccc taacttcttt
    21781 atcttttcat tataccatat tttagaagtt ttccaaaaag gaaaaaagaa catcctattc
    21841 ttcttaacta tcttcactat ctgcctttct cacgccaatc ttattttcaa aatcaattca
    21901 aaaaaataag tggctacaca ccacttcagt atcggaaaga aaaacgttga ctatttgtga
    21961 aaaaagaaaa tgccggaaaa ttccgacatt tttttagtaa gctaacttcc tgaaaatagg
    22021 agtaaccaaa catcccagaa ggcagtgata ttgatgagaa tatgaactag tattggatag
    22081 tagagatttt tagtcatgcg atacaataga gctaaaatca gacctccact agcataaatg
    22141 aaaaaagcaa gaggagttaa agcaaaattg atatgaatat aaccgaaaat aatagcagaa
    22201 agcaaaacat ctccgtacca aggtgagttt ttgaaaaagg ttgtcataag cacacctcga
    22261 taaatcaatt cctcagcaat aggggcgatg aagcaaacga tgagcaagaa ataagggaac
    22321 tcctgtctcc ccatcatttc tatcgtttca ttcaaagaaa tctgatttga agacagggat
    22381 atgaaatacg aaaagaggaa gtcagacata tatgaaatga tgtagcccag taaaaggtag
    22441 atgaagtacc tcagctgcca cttgaaatga aaaattttct ttcctgcaaa aaccagtaga
    22501 tagatgaccg ctaagaaaag aactccgctc tccatcaaaa gcagaatctg aaaaaattca
    22561 cgacttgctg gtagataggg ctttgcgagg tgattgaaaa ctctccaaaa ccaagttgat
    22621 ttgtaaaaaa ttaaggacaa tgctagtaaa atttgaatag cccgtttttt catattaaat
    22681 tctctgcttt ctccccttgt ttcttcatat tactaataaa ttttacttaa aatctcgcag
    22741 cacttccttt gcaaagatga ttgcctcctc caatatatcc taaatcatag gtgcctctgg
    22801 gacaaaatcc atgaaccggc agagttaata ctggttctat ttcccaatcg tacctaccat
    22861 taggattttt accatatgaa tctgctccac cttgtatcag ctctaattct tcatttgtta
    22921 gatttatatt ttt
//
LOCUS       DAVLBN010000034        21362 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLBN010000034 DAVLBN010000000
VERSION     DAVLBN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.034"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(439..2166)
                     /gene="ezrA"
                     /locus_tag="VXC24_001304"
     CDS             complement(439..2166)
                     /gene="ezrA"
                     /locus_tag="VXC24_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0493414.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2248..4194)
                     /gene="gyrB"
                     /locus_tag="VXC24_001305"
     CDS             complement(2248..4194)
                     /gene="gyrB"
                     /locus_tag="VXC24_001305"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0493415.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4209..4772)
                     /locus_tag="VXC24_001306"
     CDS             complement(4209..4772)
                     /locus_tag="VXC24_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0493416.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4857..5411)
                     /locus_tag="VXC24_001307"
     CDS             complement(4857..5411)
                     /locus_tag="VXC24_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0493417.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5422..6645)
                     /locus_tag="VXC24_001308"
     CDS             complement(5422..6645)
                     /locus_tag="VXC24_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0493418.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6682..9132)
                     /locus_tag="VXC24_001309"
     CDS             complement(6682..9132)
                     /locus_tag="VXC24_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0493419.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9332..10261)
                     /locus_tag="VXC24_001310"
     CDS             complement(9332..10261)
                     /locus_tag="VXC24_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0493420.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10401..10688
                     /locus_tag="VXC24_001311"
     CDS             10401..10688
                     /locus_tag="VXC24_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0493421.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10722..12056)
                     /gene="ciaH"
                     /locus_tag="VXC24_001312"
     CDS             complement(10722..12056)
                     /gene="ciaH"
                     /locus_tag="VXC24_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0493422.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12046..12720)
                     /gene="ciaR"
                     /locus_tag="VXC24_001313"
     CDS             complement(12046..12720)
                     /gene="ciaR"
                     /locus_tag="VXC24_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0493423.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12829..15375)
                     /locus_tag="VXC24_001314"
     CDS             complement(12829..15375)
                     /locus_tag="VXC24_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0493424.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15498..15938)
                     /locus_tag="VXC24_001315"
     CDS             complement(15498..15938)
                     /locus_tag="VXC24_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0493425.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15913..16782)
                     /locus_tag="VXC24_001316"
     CDS             complement(15913..16782)
                     /locus_tag="VXC24_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0493426.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16824..17552)
                     /locus_tag="VXC24_001317"
     CDS             complement(16824..17552)
                     /locus_tag="VXC24_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493427.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17560..18039)
                     /locus_tag="VXC24_001318"
     CDS             complement(17560..18039)
                     /locus_tag="VXC24_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0493428.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18050..18748)
                     /locus_tag="VXC24_001319"
     CDS             complement(18050..18748)
                     /locus_tag="VXC24_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0493429.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18741..19007)
                     /locus_tag="VXC24_001320"
     CDS             complement(18741..19007)
                     /locus_tag="VXC24_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0493430.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19073..19999)
                     /locus_tag="VXC24_001321"
     CDS             complement(19073..19999)
                     /locus_tag="VXC24_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0493431.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20074..20889)
                     /locus_tag="VXC24_001322"
                     /pseudo
     CDS             complement(20074..20889)
                     /locus_tag="VXC24_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20893..21213)
                     /locus_tag="VXC24_001323"
     CDS             complement(20893..21213)
                     /locus_tag="VXC24_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0493432.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6469 a         4681 c         3742 g         6470 t
ORIGIN      
        1 gtaaacaaaa atgttttaga ggcctattta ccgtggacta aagttgtaca agaaaaatgc
       61 aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa
      121 tagacttcgt tattggacgg ttaccaagtt actcaaagta cagatttgaa gctgcagata
      181 agactgacga aatcacttta atactaaatg aaaatcaaaa agcaaactaa gaagctagcc
      241 tcaggctgta cttgagtacg gtaaggcgac gctgacgtga tttgaagaga ttttcgaaga
      301 gtataaaaca ctgttttgag gtggtggata aatcggctgg gtaaaaactc aatctcagga
      361 gaaaatgaag taaatctccc cacaactata gaaaaagatt tgattctgct cctcacacaa
      421 taaaatcttt ttcttttatt aaaaacgaat cgtttcacgt gttttctcat atgaggtaac
      481 aaagcgattg gttacaccag gctctgccac ttccaatgct tgagaaatct tatcaaatga
      541 agcgtgataa tcaaattctt tttcaaaaat atctaaagct tcgttaaatg cttcttgaat
      601 gcgttcatca aatgagcgat agcggttaga atattgcaag agttgctctg tcaaagttgc
      661 atattgtaca atattataag tttccgtttc taaagcttcc atatcattcg ttgcaatttc
      721 aagaactcgg gtaacagatt caatgttaat cattttttgt tctaactcaa ccattaaatc
      781 ctcggtatta ttgcttgccg taaagaataa cttcaagaaa gtttgtggaa tacctggcag
      841 attgcgtttt tccatgtatc gcttgatagt atggagacga ttgacataaa cattggcctt
      901 ttgacgtgca ttaatatcat ctttctcaat ttgtgtcagg cgctcactaa ctgaaatttg
      961 ctcatcttca atatctttta gttgagtttg taaatcctca agattttctt caagaactga
     1021 ataagcttgg ggtggttctt cttgatttga agttacctca acaatagctg cctcaaaact
     1081 ctctaattct gtctgaatac gacgaacatg gcttgcagct gtctcaggaa gtaaataggt
     1141 cttgttcaaa cgtgcaatat cttctcccaa taaagtatta ttctctttca tatgttgaag
     1201 ataagttgga agagttgcaa gtagattttc cactactttc tgagcagcaa tttctcgagt
     1261 aaaaatatca tacaaggcat tgatttcctc ttgtgcctgt ccattctcat attcggcatt
     1321 atccaattcc aactgacgaa tattctcttg gtttttcttg aatgcttcat aaagcaagtg
     1381 gaaacgcgct tcaatatccg tttcaacaaa atgataatta gcatcaatta gtttacgata
     1441 accggcttcc aaatcctgta attgatctgg caattctgta gaaagcgtcg taaccaaggc
     1501 tggaacacga tccacaatat gacttaaggc caaaatgtga ttttctgtat tatccaaaat
     1561 cactgcggct tccacagggt cacccgatga attcaaggtt acaaattgtg aaaattcaga
     1621 ttggatattt tctaattgtt tttcaatttc atccaaggct tgaccatact gttctgaatt
     1681 ttcagcaact ctatgctgaa gttcctcaaa taaatccaaa gcatgaagaa cacgaccact
     1741 atttttagat tcttgcttct ctaagtctgc caaagcattg cgaattgccg caatatcttc
     1801 ttcaatcaaa gtaatttgac tctcaatttg gtcaatttga tgactggcct tgagaaaacg
     1861 aaatgaatgg ttataacctt ctgcttcaaa gagattattt tcaatatcgg caaaagagtt
     1921 gagagataaa tcgacccatt tttgattcca ttcacggaaa gccacttgac tttgtccaat
     1981 caagtgcata ttttttacag cttctacttc atcatttact ggaagattgt atagttcttc
     2041 ttttctttct tctagtgcct ctaatctccc ctcgtttcgc ttacgtagaa agattgccac
     2101 tacataagcc agaactaaaa tgactgcaat tgcaaccatt aaataaatta gttgtccatt
     2161 agacatatca aactcctttt ttacttgaaa caatcgtaac gattatatca tattttttag
     2221 accaagggaa ctacttctcc ctatttttta gacatcaagt gtactataga cagcattttc
     2281 ttcgataaac tcacgacgag gctctactcg atcccccatc aacatatcaa agattttatc
     2341 tgcttctgca gcatcatcta cagaaactct agccatcaag cgatgttcgg gatccatggt
     2401 tgtttcccac agctgatgat cgtccatttc acctagcccc ttataacgct gaatagtcgg
     2461 tttggtacga ccttcactat aacgggctaa agcttcttgg agtttgattt cttgatctgc
     2521 acccggctgg atatattctt taatctcgct tccaaccttg acaccataga ttggtggttg
     2581 ggcaatataa acataaccag cttctaggat tggtttcata taacgataaa tcaaggttaa
     2641 aagaagggta cgaatatggg ctccatcgac atcggcatcg gtcatcaaaa cgagtttttg
     2701 gtaacgggct ttcgaaacat caaattctgc gccaaatcct gttcccatgg ctgtgaaaag
     2761 actacgaatt tcttcgttag ctagaatctt atccatactt gctttttcaa cgttcaaaat
     2821 cttaccgcga attggaagga tagcctgaaa ctcacggtta cgaccagatt tggctgatcc
     2881 accagctgag tctccttcga cgatgaagag ttctgtttca gcagggttat tagaagaaca
     2941 gtctgctagt ttccctggaa ggttggaaat ttccaaacca gattttttac gtgtgacttc
     3001 acgcgcacgc ttggcagcca cacgagcctt ggcagctaaa atcccttttt ccacgatacg
     3061 tttggcaatc tgtggatttt ccatgaggaa atcggagaag gcttcactga agaggcgatt
     3121 ggtaatcttg accacttcgc tatttcccaa tttggtcttg gtttgtcctt caaactgtgg
     3181 atttgggtgt ttaactgaga taactgcagt taatccttcg cgaacatctt cccctgttaa
     3241 attatcttca ttgtctttca gtaacttatt cttacgagca taatcattga taacacgagt
     3301 cagtgccgta cggaaacctt gttcatgcgt tccaccttca tgggtatgaa tattattggc
     3361 gaaactcatg acattttcat ggtaacctgt tgtgtactgc atggctactt caactgtaat
     3421 atcatccatc tcaccgtctg tatagattgg tgtatcaaag attacatcct tgttctcgtt
     3481 gatatattca acgtaactag caatcccacc ttcataatga taatgcttgg tttgttccaa
     3541 accttggcgc ttatcagtga tggaaatttg aagaccgcga tttagaaagg ccaactcttg
     3601 aatccgttta tttaatttat caaaatcaaa gattgttgtt tcagtgaaaa tttctgggtc
     3661 cggtgtgaag tgaaccgttg ttccagttct atctgtatcc ccaaccacct caaggtctgc
     3721 aacaacatga ccacgacggt attcttggta atgaatctta ccgtttttat ggacataaac
     3781 gtctaattga gtggaaaggg cattaactac tgacgacccc accccgtgaa gaccacctga
     3841 aaccttgtat ccaccaccgc cgaactttcc tccagcatga aggactgtaa agacggtctc
     3901 aacagcagga cggcctgttt tttcctgaat atcgactggg ataccacgcc catcatccac
     3961 aacagtaatc gaatcatctg gctcaataaa aacttgaata tggctggcaa atcctgccaa
     4021 ggcctcgtca attgagttat caacaatttc ccagactaga tggtgaagac cttcttttga
     4081 ggttgatcca atgtacatcc ctggacgcat acgaacagcc tctaagccct ctaaaacttg
     4141 aatttgactg gcatcataat cctgtgcctg cagatttttg atttcttctg tcatcttatt
     4201 cctttttctt atatgtctaa tacttgtctt aaattcacga tactggtaaa caagtgggta
     4261 tcaagtcctg cagcttgacc tgcttcgata tcaatcggcc gatcaccaat gacaagacca
     4321 gagctaatct gatacttttc tcttaaataa agcatggatt cgggatttgg ctttctctta
     4381 aagcctgagc tagaagtcac cacttctgta aaataagctg ctatagaggt tttttctaaa
     4441 atttccaaaa cctgatcatt tcgatgagag accaaaaaat gacggccacc ttgatttgaa
     4501 atgacttcca ataggtcaga aactccttca aataaaatcg ggtgttcaag ctctctggct
     4561 tcattttcct tgtacttttc taaaaaattc tctaaattgg gagcgaatgt ctcaatcgca
     4621 aaaggagtag aaacctttaa agcttgatag acactgtcat ggtcttgtgt gataccatac
     4681 agtgccaatg tttcaacaaa tgcagctgtt gaagtttcat aattatccag taaagttcca
     4741 cctaaatccc agatgtaatc gtgatatttc atgcccttta ttatagcatt tttttatgaa
     4801 aaaagcgatg atttccctga gttttccaca taaaaaacga gagaataact cccgttttac
     4861 tgatttttac caaagacatc ttgatagagc attcctgttc gtaaactctc tgcgtcccct
     4921 cctagttgct ccaccaactc gtaggcaaag gcaagggctg ttgaaggacc ccgactggtt
     4981 gtcaactgac catctaccac tactgtttcc ttgacgtagt gaccatcaag gatttgctct
     5041 tgaacgccgt cataacaagt gtatcgctta tttttcaata tctctgcttg attgagggca
     5101 attggtgccg cacaaatggc tgctagtttc ttcccttctt gctcgaagct ttgcaattct
     5161 tgaatcaagg tctgattatc acgtaaatgt gcagaaccag gcatacctcc aggaagaaca
     5221 atcatatcat agtctgataa atctccatca aagacatgat ctgctcttac ttggattgca
     5281 tgcgaacccg ttacttgctc ttcaaaacca accatatcac atgtgatatt ggctcgacgc
     5341 aagacatcta caactgtcaa ggcttcaatt tcttcaaagc cctgagctaa cataactgct
     5401 acttttacca tgattttctc cttatttaat ttgttttaat acaacctttt tccgtttgaa
     5461 tgggactttt ccgctctttt cttcagctaa attagtctgg taactcatcg ataaaagcaa
     5521 accaacacca atcaaattac tgataatagc tgatccccct tgcgaaatga aaggcaaggg
     5581 aatccccgtc aaaggaagta gtccagtcac agcaccgata ttctcaaaga tgtggaagag
     5641 caacatcata atcaaacctg tggaaatata agtgtagaac tggttatttg atttaagagt
     5701 aatcttcaac atacggtaaa tcaacatgag atagagggca ataaccagga cagagccaat
     5761 aaagccaaaa tcttctgcaa taaccgtaaa aatcatatct gactctcgaa ctgggataag
     5821 cagattcgaa gcattaaatc cctgaccaaa taagccacca ctcccaatgg caatctgccc
     5881 ttgagcctgc tggtaagtcg ttgtttgggc aaactcaaag ggattgagcc aagccaaaat
     5941 ccgattaatt tggtaggtcg gcattccaat ctggtgaaga aaagctcgtc cgtccttgct
     6001 aataaagata gctaagaaac cagcaactcc tgttacagca gtcacaaata ctgggataat
     6061 aattttccaa gaaacccctg ataataaaac gattcctgag aaaatggcta caaaaaccaa
     6121 agccgtcccc aagtcacttt gaagtgctaa aagaactagg actggaatgg taaagagaat
     6181 catccagaaa attaacaaaa agtccagcgg aaccgtgcgt ctccattcct tatgtttctt
     6241 tgtaaattgg acaatgacac gagccaacat gaggatatag gatatcttca taaattctga
     6301 cggttggaat agggtaattc catttattga tacccagttt ttggcacccg ttgatgcaac
     6361 taagcttgga ttataaaata caatcggcaa gatcataagt cccaagccta aaatatatag
     6421 aaagggggtc accttccaaa gaaattctgt attaaagagc atgaccacaa aaccaatcac
     6481 aagccccaag gcaatccagg cgacctgctg ccctaaaatg ggcagaatat tattgggata
     6541 atcatgacta acggctatat agatagccac cacaccgatg accagtagaa aaaatactgg
     6601 caagagcaaa ctgtaatcga ctcttgagtc gagagaacgt ttcatatata ctaaccttat
     6661 actttcatac aatactattt atcaaagttc attaaaaaat ctatcaatag cctcgtcaac
     6721 ttcggatcga gagatggttt taacagtcgc ttcttctgct agagatgcta ctatttgttt
     6781 gccgtatcgt tttccgacga ttctcctatc caaaataaga gttaaggaac gttggtattc
     6841 acgtctcata cttcttccca aagcctgttt taaacgaata atggccattg gcaattgata
     6901 atcataaaag gcatttttcc cttcttgatt cagttcttga ttaatctttt tcgtcaaggg
     6961 ttcttgagga ttttggaaag gaagcctcgg tacaacttga atcacaaaag gatggcttga
     7021 aaaatcaact ccctcccaga aacttgctgc accaagcaag atttgttgtt cacctttttc
     7081 aaagcgtttc tttagctgat gaacatcccc atttttatac tgggccaagt ggctaactgt
     7141 aagtaaatcc gatactgcta gaagcatgtc tttagcggta aagagaacca aaatcggttg
     7201 ctggaaagct tgaatttcca ctagtaaagc agctacctct ctggcataga cttctaagga
     7261 ggtttctgtt accagaggga aatctttgac cataaccact tcttgttcct gttttccccg
     7321 agattcaatc ttgacaaatt tggcttcagg atagcctaaa aggtctgcca aagaaaccct
     7381 ctgactaatc tcaagagtag ccgatactcc caagacttgg caactctcag gaagtaaaga
     7441 ggacagaaga gtacggcctg attttgtaga agaaatctga attttctttt gactcgtttc
     7501 agttacttca agccagtaat caccttcagc tgtaaaatag cgaaccagct catcaaagcc
     7561 ttctacttct aattctgaaa aatactgatg gagattgtcc agagaatcta agatattttt
     7621 cctagattta ccagactgaa attgttctat caagtagaga cactcaaagc gaatactttc
     7681 tagtatccgt tgttgaaccc tgttttcttc tcctactaaa gccttatcaa ttaaatcgat
     7741 aatagattgt atatcgtagg tctcttgaag cagattttct agagctaaca aaatcttttg
     7801 gacttcatca ataatcagta aacggtcact gacaaattca ggattatctt caagtctggt
     7861 cacgagatag gcatgattag tcactaaaag cttgcaagtc tctgcccttt cttgactacg
     7921 tttccaaaaa tcttccgtca caaataagct ctgggatgat aaattcccat catgacgaag
     7981 gtctgctaga aaatgttggt aacggtagag ttgcccgatt tcatccaaat ctcctgtctc
     8041 tgtctcagta agccagacca agacttgcat tttaaagcgt ctaaataagc gattttcatc
     8101 attttcctgc aaggaatgat aaaaggcatc caacttcaga taattttgtg gtccctttaa
     8161 gctatgaata tctgtatgga acacttcctt gagacgttta ccttcttctt ccatgatttg
     8221 attttgaaga atctttgtcg gaacactaag aacaatttgt cgctctttgg attgagataa
     8281 agcgggtaag agatagccat aggttttccc aatccctgtc ggcgcttgaa tcagagagac
     8341 aggttcatct ttcaatagca agacaacctc tttagcaaaa ctttcttgtt cctccctcac
     8401 ttcaaggttc aacagagaaa tatttttaga aaagtcttga gatagttttc gtagctccag
     8461 agaagctgcc gttttcttaa aatacagacc ttgaacttgg accaagtctg gagaactcag
     8521 gatagattgg ttgcgataag tttcctcaat aaccaggtag gactcatata ggagagcgtc
     8581 agccatttcc agcaagcgtt ccaagagacc tttaggaagc tgggtcatct tttcccgtaa
     8641 aaaaagaagt aattctgctg tagcttgggc atctgaaagg gctgtgtgtg cgtgtttaag
     8701 aggaattcct aattctcgac acaaaatcgg caagctatat ttttccagtt cagggaaaaa
     8761 gacctgggcc aattcgaccg tatcaacacg agggtttctt agctcatagc cttcaaaaaa
     8821 taaattttcc gccaagagat tagcatcaaa ctgaacatta tgggctacaa aaatcccatc
     8881 ctccaccaag tcaaatattt ttctggcaac ttgcgaaaaa tcaggtgctt gcgccagacg
     8941 ttggtctgtc aatcctgtca gttctttgat atgagcatcc aagggttcat gtggattgac
     9001 atccgtcgta tagtgatcga cgatttctcc gtcctcaatc acgacaattc ccacttggat
     9061 aattttagcc ttactacctg tgctagttgc ctctaaatcc accacaacat agcgattacc
     9121 aatcgttttc attataaaaa attataccaa aaaaagggct atttggcacc tgcaaacata
     9181 ggataatttt caaactcaag aacactactt ttcttaaaaa tcccatcgaa tagagcattc
     9241 tagcctgctg atttttgtaa aatagtgaag aaatacgaaa aattgagaga agaaatgttt
     9301 tcatcttcct tctctcaacg aatcatgtat tttatttaac catgtcagga tcgtagtcat
     9361 aaaatcctgt atcaaggaaa cggtttttag ggtgaagttt acgaacttct tcatccagca
     9421 agaaggcttg atcatggcta aagttgccct cttgaatcaa gttacgcgct tggataaaga
     9481 gttttgcaat ctcaacaaag ttctgaccag gagtgtagag cccttctagt ttccagcgag
     9541 taaagccatg ctccaccaat tctgttaatt tgatcatcaa atcaaggtca ttgttggcaa
     9601 agatatgggt cccatgatta tcttcaaaaa tggaatagtg gctctctgga tcacttggct
     9661 cagccaagaa gaggtcacgt ttatgcgtct tttcatcatc gatatgtgta aagttatagt
     9721 agttttgcaa gagtggacgt ttagaatgat ggatgacgct agcaccgtaa accaaaactt
     9781 cagcaggaat ttccaaaatc tctggcattt tgaaaagttc agctgatgga atttcacgcg
     9841 ccaaaacagc ctcagatgca ccagcctttt gtccccagaa gttaatctga cgactgctag
     9901 ttaccatggt tgaagcatcg tagatggtct taaatgaata accatcgcgg ttaactacgt
     9961 aaaagacgcc tgcatcccca atcgtaatat agtctgtctt gatttcttcc aagaagtcta
    10021 agaaaggctt gatacggtcc atcatatctt ggtgcatgag agcattgacc gcaacgagca
    10081 attccttacc agcatcatga accaacttag cgatttcacg taattggtca taactaaagg
    10141 tcgttggcag acgaaggcca aaatctttct caccgacata gatacggtct acgccagctt
    10201 cgagtagttg ttcaacttgt tcaatacttt cagcagttgc tgtaatgaca atcttttcca
    10261 taagaaaaat tataccacat ttctccaaaa tcagccatgc tttgaaaatg aaaagggact
    10321 ttattctttt tgtaaccttt ctgtaataat tctctgccga aaaaatgata aaataggtat
    10381 gtactgttaa ggagagaatc atgcccgtaa gaaaattaca atcctatgag gtagactatc
    10441 aagaagaatt aaaccagcag cttcctcatt accaagctta tacacctgaa gcgcaatctg
    10501 atgccaatct caaggaaatc ctatttttta ttaatatcgc tgttttttgt atctgtattg
    10561 ctatctttag ttttatcttt ttagcattaa aattatcaac tgctcttgcc tttgccgcag
    10621 caatcggatt cagcttactt gttttaaaag ttcaacggtc tattatcaaa cgaaaacgta
    10681 gaagataaat ccaaaatatc gccccaattg gagcgatatt tttatttttt ctttttagat
    10741 ggtgtctgaa tggcaatctt cacttcaaag attgttccct tgggtttatt atctttgaca
    10801 gtaacagttc cttttagagc atctacaatt tgcttggcta gggataatcc taaaccaaaa
    10861 ccaccttttt gccgggttct agccttgtct actcgataaa aacggtcaaa aattttcttt
    10921 ttatcttctg tcgaaatacc gattccatta tcagaaacaa gtaaataaag attgcgatcg
    10981 gtcgccgaga taagaaaatc aatttcacca tcctcctcag tatacttgac ggcattatcg
    11041 aaaagaatgg tcatcagttg tttcagaaga agctgatctg tgacaattgt tcgatggata
    11101 cgattttcaa aacggaagac acgattattt tccgaagcaa tcatctcata gtttgtgaaa
    11161 gttgtattaa aaaagctagt tggaacttct gcaagctccg gcttaatccc atcatctctc
    11221 cgagctaagt tcagcaagct tgtcgttaaa aaacgcatat ttcggacttc ttccaaactc
    11281 gatgcaatgc tttcgctcac atccataatg gtagcttctg gcttacgaaa aagggtctct
    11341 aagcgatttt gcaaaactgc gagtggagtt cgtaactcat gactggcatt ttccacaaaa
    11401 gactgttgct tctgcatact ctcaagcaag ggcctaacac tgaccctagc tagatagaga
    11461 ctggcaagta aagacaaaat ccagaaacta gccatcacga ccacaatcaa ttgctcatgc
    11521 ttttgactag cctgctccaa ctgactggta ttaatcaaga cagcagcata cttgatattg
    11581 gttgaaaccg aactaatatt ggtctccatc aaaatcacac gatagatttc ttcctgccca
    11641 tagctattaa aaacctgaat ctggtagata tgtcctagtt ctttcttttc taacttaatc
    11701 ttatccaagc ccaaaaatcg atttccagaa agaagttgag taaagtcttt atcaaagaga
    11761 atgacttccg tattggaact gacattaggt tttatttcta ctttactagc gtccgcccta
    11821 gcattttcta aatctttaat ctcttctgtt gccctattta tagccagctg aataactgct
    11881 tgaggatttt cactcagtcc atgaagctta tcgtccaccg aagtataaag actcgaatgc
    11941 atgacttgta aaataatcag agtcattgta gaaaaaatca gggtgaagac accgaagttg
    12001 cggataaaat aactaaagtc atccgcatac catgtttttt taagtttact gaacatcttt
    12061 taaaagatac ccaacactac gcaaggtttg caaattctct gcaaaagtgg ttccctttaa
    12121 tttcttacgg acttttgaaa catagacttc gacaaccgaa atcgttgtat cactatcaaa
    12181 tccccataga cggtcaaaaa tctgcgtctt aggcaaaatc acattttgat tttgaaggaa
    12241 ataaactagt aaatcgaact ctttccccag caattcgaca ggagtatctt caactttaac
    12301 ggtattggtt gataaattaa ccacgatatt cccataagtc aaggtgtttt cattaaactt
    12361 ccctgaacgt ttgagaaggg cctgaatccg cattttaagt tcttctaggt agaaaggttt
    12421 ggtcagataa tcatccgctc ccagttcaaa tccatgtccc ttgtcatcca aactttcctt
    12481 ggcagtcata atcagaactg gtgtcgtaat tcccttttca cgcaattctt ttaagacttg
    12541 gaaaccattt ttttctggca acatcaaatc cagcaaaatc aagtcataga caccactctc
    12601 agcttcgtag agaccttctt ctccatcaaa tacctgcata acatccgcaa aatcgtctaa
    12661 aaagtcaaat actgaatttg acagacctag gtcatcctca accaataaga tttttatcat
    12721 gagaaactcc tccttattaa aactattata ccaaatttgc cttaaaaaaa actcaactct
    12781 ctgcatttta catgagatag ctgagttttc tttttatttt aggcttattt atgcatttcc
    12841 gtattgaaga acaactgctt cgactgcagc tttttcacgg ctaatcaagt caacacgtgc
    12901 tgcaatttcc ttgattccca taccgatgtt acggctaaga gcaaggtcag aaagttgcgg
    12961 ctcaaagaac tccttgtatt ccgccaagcg ttgctgagtc ttaaatacat gagcaggaag
    13021 gataacaaag ctatcaaagc tcatatctcc tccaagggct gccttaatcc aagcccagtt
    13081 ttcacgcgcc caagaccaag ctgttttctg agttgcttga tgagctagga attggtaata
    13141 ccaagcagac aagtcctgtg gtttgaccac aaatttgtcc ttccaagaag taatcaagtt
    13201 ttggatatta tccgcatctg tactgtatgc aagagctgct gccaactggc gtttaaagac
    13261 agcatctgtt gcgtgagtat aagtatcaag ataaagtgct aacaagtctt tagtctcatg
    13321 atgtttcatc tcattaatca gaacttgtga acgaatagct gctgggagtc ctgcaagatt
    13381 ctccttgtgt gttgcgaaga tttggctagc gacttgacta gcttctgcat catttgagcg
    13441 aatcatcatc gaaacagcca gctgacgaac caattcatcc tcatctgatt ctccgtcttt
    13501 agcttcaaaa ccaagacggt catagttatg acgagccaat ttagcaacca gtcctttgaa
    13561 ggctgtttca gcatccgttc cttcatcaat aaagcgctca agggctgaaa tcacttgaga
    13621 aacagctgaa accaccagat aagactcttc cttagcaagt ttatcaagaa ctggaagcaa
    13681 gtctgcataa gaaatgtgcc ctgcctcagc caacaaacga cgttcttgaa caatttgcag
    13741 tttgcttgtg ttatcaagtg tctctagctc agcaagaaca gcttctaaca agtctccttg
    13801 atagtcggta atatagtggg cagtattttc agtgttgaga cgaagagctc cttcattttc
    13861 agcaagaaga gctgcgtagc cagggatttc gatactttca gtttcgagtg tatcaggcaa
    13921 gcctttccag ttgctattga ggggcaccac ccagagacgg ttcttgtctt cgttctcacc
    13981 gatgaagaat tgtttttgtg aaatcttcaa gacatcattt tcaactttaa cagtaagaac
    14041 tgggtaacca ggctgttcca accaagaatc catgaaggct gcgacatcac gtcctgacgc
    14101 ttgaccaagg gcatcccaaa ggtcactacc aatggtgttg ctgtattggt gtttttcaaa
    14161 gtaggcgtgc aaacctttag caaaatcagc atctcctagc caacggcgaa gcatgtgcat
    14221 gagacggctt cctttggcat agacgatagc gccgtcaaag agtgtattga tttcatctgg
    14281 atgtttaact tcgacgtgga cagactgaac gccatcagta gcgtcacgtt caagagcaag
    14341 aggtactcca cctgtttgga aatcttcaaa gatattccag cttggttcga tggtatccac
    14401 acagacgtat tccatcatat tagcaaaact ttcattgagc caaaggtcat cccaccattt
    14461 catagtcacg aggttcccaa accattggtg agccaattca tgggccacaa caagggcaac
    14521 ttgttgacgg ctagcaaatg tagagttctc atcgacaacc aagtaaactt cacggtaggt
    14581 cacaagaccc cagttttcca tagcaccagc tgagaagtca ggaagggcga tgtggagaga
    14641 ttgaggaatt gggtacttaa ctccatagta atcttcgtaa aactcgatag agcgaacagc
    14701 gatatccagt gagaaatcaa gatttgaaag tggatgtgct ttggttgagt agacacctac
    14761 cagggtacca tttttagttt tagcggtcac cccttgcaaa tcaccagcaa caaaggccaa
    14821 caagtaagaa gacatgcgag gtgttgtctc aaacttccag atacctgttt ccttacggtt
    14881 ttcaacatcg atttctggca tgtttgacaa ggccaattca ccttctgctt ggtcaaagcg
    14941 aagagagaga tcaaaagttg ctttggcttc aggctcatcc acacatggga aagcttcgcg
    15001 cgcaaaatgg ctctcgaact gagtagacaa gacctccttc ttgactccat caactgtata
    15061 ataagaaggg taaatccctg tcatgttgtc tgtaatttta ccagaaaagg caagaaccaa
    15121 ttcaacttga ccagcctcag ccaattcgat atgaagggct tcattgtcat ggtcaactgt
    15181 aaatggacga gcttgacctg caacttctac agaggtgatt tccaagtctt tttggtggag
    15241 ggagatgcgg tcactctgtg cttgaccagt gatggtcact ttcccagaaa aagtcttggt
    15301 ctcacgactc aaatctaaaa ataaatcata atgttcagga acaaattgct taataaaatg
    15361 ttcaactgct tgcatagttt tctcctattc taagtttaag agctgctgct cttcttcaaa
    15421 caaacttatt atatcatatt ttgcttgaga aaaaaggatt ggacagcgat ttccaaaact
    15481 ttcttccttc taatagtcta cagtgggtag accttgcgaa attcttctaa aacaaccttg
    15541 ctttcaggtg taaaagtcag ccctacttca cccaaacagt ctgtgaaaaa gtcctcatga
    15601 gcctggcgcc aataggcaag tgatttgtct ccctcacctt ccttaaaggc atgttgcgca
    15661 gagacttgat tgaagagttc aacagaaacc tttgtaattt cgacaatgca gacagactga
    15721 ttttgactat ctaaaatgac atcgaaggtc cctacttggg gaagtggttc gtcttctagt
    15781 acatagaggt cataggctga tgctgttgct gtcttttctc ctttaaacac caaatccgct
    15841 aaaaggtctg gttcaactcc aaaagcccaa gcatcgattt catctccgat caaaggattg
    15901 atttgcttgt atttattcca catttcttgc ggtatcatgg gtactccttt gtaatttttt
    15961 actttcttct tttatgtgtt taagatgatc tggatggtca atctctaaat caaaaatctc
    16021 tggaatagaa ctgtagtgga taatgcactt gatacccaac tgattcattt tttgtatgaa
    16081 agaagtattc agatagcctg ctacagcaaa attaatcttg ttctttcttg ctttatcctg
    16141 catatctctt agcatatcta acattattgg actttccata tcatgccatt gactgtttct
    16201 catagtcgca aaaacaaagg aagtcaaatc attcattcca actacaatct ttgaaatgcc
    16261 cgtttccagt atactagata agtcaaaata cgctgacggt aattcaatca tcgttccgac
    16321 tttcccagta aagccatact gacgcaatac tgtaatagct tgttttaatt ggtcggcatc
    16381 attgacagaa ggaaagataa gagatagatt ggggttggtt tgataaactt ctgtaacgac
    16441 atgtgcttca gcctgaaatt catccaaaca cgccagtaaa cgtctggttc ctctatagcc
    16501 aaacaaggga tgcccttcgt caaaaaactc tctagtcccc actaaacaat tggcttctgt
    16561 attcgttaat tcagaaaaac gataccaaac ttcttcatct gagtacaggg agcagatagt
    16621 ctctagataa tcttttacaa attgctgaca acttgctaat atgatgtttt gattaagctc
    16681 tctcaacaaa tattccccac gaatcatgcc gacgtggtga aatagttgag gataaatttt
    16741 ttcaagaatt ttttcgccac taagggcaag ttgatttctc atagccattc acctcgtctt
    16801 aaaagataca atatcatata taattatatc aaaatttcct ctagttcaaa agcttcataa
    16861 ggttcagata actcatatcc taaaaattct gctacttttt tggaagcctc attatgagca
    16921 tcccaaagtg gaaacatatc tctatttaaa ctctctagaa tcattgcagc accaagcttt
    16981 ttagcaaatc catttccttg ttcgtttggt ctagttgcaa cttccacttc aactgcttta
    17041 cggtaaacta accctgagga aatcccagca atcagttcat tatttttaag aatcacaaag
    17101 ccaaatccac cttttaaaac aaaatcctga taggactcaa aatccccctg taaatcctgt
    17161 gaccattctt ccgtagaaaa gcagttataa atatgattat caataggcac aatattgtaa
    17221 ccttcctcta aatgagtaac tagattattt aaaaattcaa cttgaaaatt tgccttatct
    17281 ttaaaagaat agcgagtaaa agaatttagc cccacttttc gatgcagaaa atcttgccaa
    17341 ttagtatttt ctgaaataat aatcttataa tctaaaccat attttctaac aaaatcttcc
    17401 caaaatctgg aatccaactc ccctgctagg tatagaaaat tcccaacatc ataaaagctt
    17461 gttgtcctat cattgtttcg gtagacagtt ccaatttgag atttaagacc atagagaacc
    17521 atatttttct tccatgtttt aaatagttcc attatccctc tacttcacct tccaattcat
    17581 gtaagaagtc ttgtccagtt ctggcaatcc taataattca gacttaacct tcaagactaa
    17641 tggcgatgca ttttcttctg taatctcttg aatatccatc caaatatatc caagtgaatc
    17701 attcgcacca tcagacacag cttccgaaat cgtaacttga ggtgcactct cattcatttc
    17761 aacatcatac aaggctatga catggtgaac cataaaattt tttaactctt ccctgacgaa
    17821 aacatcgtag attcgaggat tagagtagct tctaacagta aatcccgtct cttccataac
    17881 ttctctagtc agcgtttccg tcagtccttc accaagttgc tgactgcctc caggtagatc
    17941 ataccgatgt tgataagggc ctctcgtttt ttcaatgcaa agtaactttc cattttcaaa
    18001 gcaaacacag tagaccccaa agtgattttt gatttccatc caactcctcc tacttcaaag
    18061 accagccacc atctattgtc agaatttgtc cctgcatggc agatgccttt ccactggcca
    18121 aaaagagact gacttctgcc acttcctctg gttcaatcca gcgcttgatt ggtgtttcac
    18181 tagccaccca gtcagctaag ccacctgtct caaaatccgc agcggtcata gctgtcttga
    18241 ctgctcctgg agcgatacca aagacctgaa tcccagcttc agcatagtct agagccaact
    18301 gcttggtgaa gccagccaag gcatgcttgg atgaagtata ggcgtgacca cctccacctg
    18361 ctaggctaga agcaatggaa cacatattga tgatgattcc ctttttattt tccagcattt
    18421 gtgtcaaata ataccgagtc aactctactg gaataatgta gttgatttca aaaatctctt
    18481 gaatgtcctg cgccgtttgt tccaacagtg gtttgtaatc atccaaaact ccggcagtat
    18541 tacacaaaac atccacctga gggcaccagt caaaaatagg ttccaagtcc aaggtcaaat
    18601 ctctctgtaa aaagtgaaaa tcaccctcta agagtggctt ttcaccttgg tcaactccat
    18661 aaacttgata gcccttctct aaaaagaggc gagcttgagc caatccgatc cctgaactca
    18721 ctcctgtaat gagtacacgt ttagtcatgc acttctaccc aatccgttgc caaaacatca
    18781 caaactgtcg ggctccacat ggaaaaacct tctccttctc cagaaacgtt gattaggaaa
    18841 taaggtgtca tttcaagtgc aagcccattt tgctcgatgg tatcaaagag ttggacatag
    18901 ttttccgcac ctccccaacc agttcgtaca tattttctct tagcctttaa cccaggcagg
    18961 atctcttcaa atgtcatgtt tttctccttt aattctacat tcttcattta attatagcaa
    19021 aaaaccactt tatacggctt tttgactgtg agttattcaa acctgctact acttacggca
    19081 aattattccc tgcagcaaga taaatttcat accattcttt tcttgttaag ctaaagtttg
    19141 ccgctcggct aacttctctc aagtgcttag gatttgttgt acctacgact gcctgcattt
    19201 ttgctggata acgcaatatc caagaaatgg caatagttga agaggttact ccatatttaa
    19261 tagctaaacg atcaagtact tgatttaaag cttgaaattt ctcatttcca acaaagttcc
    19321 ctttaaaata cccgaattgc aagacagacc atgcttgaat gaccacatcg tgtaatttgc
    19381 aatattcaaa aatgctgcca tctcgcatag ctgcttgact atcttccata ttaacatgaa
    19441 aagctgattc aaatcctgga gtaaaagccg cactcaattg tagctgatta acagctaacg
    19501 gctgcttgac atctttttta agcaactcca tcatcatagg attttgatta gaaactccaa
    19561 aatctcgaac tttaccttgt ttataaagga gatcaaaggc ttctgctact tggtcagatt
    19621 ccatcaaagc atctggtcga tgaaggagca agctatctag atgatcaatc ttcaatcttt
    19681 gcaaaatacc gtctactgat tttataatat agtccttaga aaaatcaaaa taggtaaatt
    19741 cttcaatgcg aatgccacat ttggactgaa tccacatctt ttctcttaaa tctggacgat
    19801 tttttaggac aagacctaac agttcttcac aacgaccacg accataaata tcagccaagt
    19861 cgaaggcatt gattccaaca gaaagtgctg tttctacaag ctcttcaact tcttttacag
    19921 acttatcttt tattctcatc attccgagaa caatttctga taattctttg tcatcttgac
    19981 caagagttat gtatctcatc aaatttttct cctttaattt ctaacattct tcccttcatt
    20041 ataacaaaaa accgctttgc aacggctttt tgactatact tcactccatt ttatcttctt
    20101 aaacccacgg aacaagacaa agattccaat aaagaggaca gctaaaggaa taacttttgt
    20161 aaggaaaaca tttgaaattc ccatctactc ataataacgg agcagagaac ccaccacaag
    20221 atgggcaata atcatactga caaatggacg aaagaccgct tctttccaat tccaaatacc
    20281 gataactagc gaaatcgtaa agacagacaa actatcccag ggagccggaa tataaaaggc
    20341 tccttcttgt atgaagcttg ccattcctac atatcctaaa acaactagaa gaactatagt
    20401 cccaacaaca atgtaagtgc caattttcat tttaggagaa tcttggacta aacttcttcg
    20461 taaaattgtg gccacaagtc caaatccaat cagaaaaata agaagttgcc ctaaaaatgt
    20521 gagcaaattg actgttaaga gaggaccttt agaaaaatca cttagtagtt gataataacg
    20581 taataccgcc aggacaagaa ttggcgtcaa aagggactct ttgatagaac tgcgaggtgc
    20641 tcccttgaga atctctttca ttattttttt aggattctta cctagataat cctctgcact
    20701 catgccatct cgttctgctt ctgagaaatc tagcatcatc aaatagatct gctctctgag
    20761 atagtcttca tcatagagaa atccagcaag attaaaactt tcccacaact cctcaaaata
    20821 cttttgattc tcctcagaaa actcatgtag caaagcgctt gtttcttcgt aatacttcat
    20881 tttcttcatg gtttaacccc cattcttaat cccttctact ttttgactca aatcgtccca
    20941 ttgttgccaa aagactgaga cacgctcttc tccttctttc attaatgaaa aatacttccg
    21001 atctggacca tctggcgacg ggcgcatgtc gcctcttatc cattgatttt tttctaactt
    21061 ttgcaacaaa ggataaatag ttcctggaac gatagtatca aatccagcct ctcgcaaagt
    21121 ctgaaccaac tcataaccat accgctcttt ttgaccaatc atatccaaga cacaaccttc
    21181 aagaacacct tttaatagct gagtttcttt catcacttct cccttctaat ctattttgta
    21241 atacctacta gtaacttcac ctatagtata tcacttctac actagtttgt aaagcataat
    21301 agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccctacc gtatgtatgg
    21361 tt
//
LOCUS       DAVLBN010000035        21162 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLBN010000035 DAVLBN010000000
VERSION     DAVLBN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.035"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..244
                     /locus_tag="VXC24_001324"
     CDS             <1..244
                     /locus_tag="VXC24_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493433.1"
                     /translation="IIYDNEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVI
                     NEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            558..1535
                     /locus_tag="VXC24_001325"
     CDS             558..1535
                     /locus_tag="VXC24_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493434.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1912..2286
                     /locus_tag="VXC24_001326"
     CDS             1912..2286
                     /locus_tag="VXC24_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0493435.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2494..3396
                     /locus_tag="VXC24_001327"
     CDS             2494..3396
                     /locus_tag="VXC24_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493436.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3452..3805
                     /locus_tag="VXC24_001328"
     CDS             3452..3805
                     /locus_tag="VXC24_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0493437.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            3802..4530
                     /locus_tag="VXC24_001329"
     CDS             3802..4530
                     /locus_tag="VXC24_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493438.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            5662..6165
                     /locus_tag="VXC24_001330"
     CDS             5662..6165
                     /locus_tag="VXC24_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493439.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQDGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            6452..8497
                     /gene="pspA"
                     /locus_tag="VXC24_001331"
     CDS             6452..8497
                     /gene="pspA"
                     /locus_tag="VXC24_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0493440.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTLVRAEEAPVANQSKAEK
                     DYDAAVKKSEAAKKDYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMAT
                     GWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            8897..10018
                     /gene="mnmA"
                     /locus_tag="VXC24_001332"
     CDS             8897..10018
                     /gene="mnmA"
                     /locus_tag="VXC24_001332"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0493441.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTNLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            10159..10614
                     /locus_tag="VXC24_001333"
     CDS             10159..10614
                     /locus_tag="VXC24_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0493442.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            10624..12537
                     /gene="mnmG"
                     /locus_tag="VXC24_001334"
     CDS             10624..12537
                     /gene="mnmG"
                     /locus_tag="VXC24_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0493443.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            12741..12818
                     /locus_tag="VXC24_001335"
                     /pseudo
     CDS             12741..12818
                     /locus_tag="VXC24_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12916..14595)
                     /locus_tag="VXC24_001336"
     CDS             complement(12916..14595)
                     /locus_tag="VXC24_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0493444.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(14597..14830)
                     /locus_tag="VXC24_001337"
     CDS             complement(14597..14830)
                     /locus_tag="VXC24_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0493445.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            15110..15325
                     /locus_tag="VXC24_001338"
     CDS             15110..15325
                     /locus_tag="VXC24_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493446.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(15648..15800)
                     /gene="cibB"
                     /locus_tag="VXC24_001339"
     CDS             complement(15648..15800)
                     /gene="cibB"
                     /locus_tag="VXC24_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0493447.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(15802..15987)
                     /gene="cibA"
                     /locus_tag="VXC24_001340"
     CDS             complement(15802..15987)
                     /gene="cibA"
                     /locus_tag="VXC24_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0493448.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            16165..16848
                     /gene="tsaB"
                     /locus_tag="VXC24_001341"
     CDS             16165..16848
                     /gene="tsaB"
                     /locus_tag="VXC24_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0493449.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            16845..17282
                     /gene="rimI"
                     /locus_tag="VXC24_001342"
     CDS             16845..17282
                     /gene="rimI"
                     /locus_tag="VXC24_001342"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0493450.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            17272..18282
                     /gene="tsaD"
                     /locus_tag="VXC24_001343"
     CDS             17272..18282
                     /gene="tsaD"
                     /locus_tag="VXC24_001343"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0493451.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(18322..19628)
                     /locus_tag="VXC24_001344"
                     /pseudo
     CDS             complement(18322..19628)
                     /locus_tag="VXC24_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(20020..20100)
                     /locus_tag="VXC24_001345"
     CDS             complement(20020..20100)
                     /locus_tag="VXC24_001345"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0493452.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            complement(20301..20627)
                     /locus_tag="VXC24_001346"
     CDS             complement(20301..20627)
                     /locus_tag="VXC24_001346"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493453.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVKTYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            20864..>21162
                     /locus_tag="VXC24_001347"
     CDS             20864..>21162
                     /locus_tag="VXC24_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0493454.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKN"
BASE COUNT         6581 a         3689 c         4547 g         6345 t
ORIGIN      
        1 aatcatttac gataatgaag cattaagaga tttgtcaaaa caatatttaa acaaaaatat
       61 ttcggaatta caagatggtt ctttcgagga cggtatacaa gatgctgttg cctctaaaca
      121 aatagtagtt ataaatgaat ttatagcttg tttaaattcc agatgcgtgc catcccaata
      181 tgatagattt ttttataaag atagacctta tattttttcc agaaagagtc ctattaaggg
      241 gtgaaaattt gttacatttg gattaacaag tgtcctaggg attagaaata actctagtat
      301 agctagatat ttttgagtaa ctagaaatat cattagtcta cccatatgat tgccagaaaa
      361 gatggctgat gaatcttatt tatactgttg cagtaggcgt tgtctaggat aaataagcta
      421 tcttgatggg ggagattgga ataattttag tagaaacatt aaaggattat ggacaagtag
      481 cgcaggatta ggtgatgcaa tgtgctaagt tggcttggtg ttagcagtag tattatttaa
      541 caatggaaag tagactaatg aaaaataagc gttatttttt tgacacaatt ttaataattt
      601 tactgcttat aagcacgata ttttgtgtca gcccagtatt tataaaattg gacatcttag
      661 gaactccctc tcatgccatc ttaacctttg tattggcgat accgttattc tatattttgt
      721 ctcaatgctt acatactttg ctattactag tttcctcaat cttttgtaaa ttaagaccaa
      781 tttattttta ttttatattt gtgatcatta taggagctag gaaatactat cgaattctct
      841 ttcaccaact aatgggattt agtccaggaa tagcagtgtt ttataaggag agtcaaacaa
      901 ctaagaatct gtttaaattt tactacttct tgtactttac aacactaatt tcatactatt
      961 ttttctttac ttttgtgtat gacaaatcgt tgcttttgcc tcttattcca ttttctatta
     1021 tcatagcatt agtacaaaaa ctttatagaa ttgagaatca acaattattt ctgttaaaat
     1081 caaaagtact aacaatactg gaatctaaga gggattgtga gtttaatctt caggattatc
     1141 atgaaatttg gaaattgcaa tcaaaatctg agttgccatg cgtggcttta tcttatatca
     1201 gtttgatcaa gccatatctt tcagagagtg tgcgtgaaca aattgattta ttagaagtta
     1261 agcgatttaa aaaaataaat catccaatat cactttatgg tatgttggat gttataaaat
     1321 taaatctata tttacggcat tataatgaaa aaaataaata tgaatcaatg ttaaagaaaa
     1381 ttttagaggt aagaccagac tttgttttaa tcgagcagaa tattgatgat agtttaaata
     1441 gctcgcaacc cttatcttta tctttagcca tttcagaaat ccaacttttg cttgaagtgt
     1501 atatggggat caaacatgtt tcaattagga gataaaacca gaataatatt tgccattata
     1561 ggggcaagtt gcatattagt cagtatgtat cttattccac ttattaaaac tgagaataaa
     1621 ttttgggaaa tacttttatt tatattaggt gtattgctaa ttggaattgc gttactaagt
     1681 caaaaaaaat aaattttgaa atagtattag tgagttcgca attatttatt gctagtggtt
     1741 tagaactgtt aagtttcaaa caataattga ttttaaacct taggtaacct ataaaaacaa
     1801 ataaggtaga gaaaggatat cttatatagg tagctaagtg ataaaaacac agtcgtctat
     1861 cacttgttag gaaactatcc taactatgct taataaaaaa ggagaaaata aatggaactc
     1921 gtattaccaa ataattatgt tgctcttgag caagaagaga tgatgtatct tgatggggga
     1981 ttttctattc tgagatggcc tgttgcaaca gccattaata tagcttttaa tggtgtttta
     2041 ggtggaggag caatcagtct agttagaaat tatattcgta attatggttt gcggcgagtt
     2101 acaagcgcaa ttgctggagc agctgcaaga tatgttgggg tacgagttgc aaatagagtg
     2161 gcaggatttg cactgtctgc tattaatgga tttgcagctt ggatgtcaat tggcgatgct
     2221 attacaacaa tctgggccaa caatgatgta aataggagag acccaaattt aaacgccttg
     2281 tggtaactag atatgggtat taaaatggaa aaaatttttg ttattatttt ttttgtatgt
     2341 ctatttatat catccataac ttttttagcc tatgattttg ttagcgaaga aataaaaaaa
     2401 ttgattattt ggatgaatgt cgtttttttg attttaatca tagcaatgat aatttatcca
     2461 aaattaagaa aatgataagg acactgtaaa attatgatac gtaaactaat cattttttta
     2521 ttaatgctcc ctctttttgt cttgtggcta gagttgcatg tcctagtgaa taacttacta
     2581 ttgaatctag aatctcccct tgattttgtg attagtatga gtcttgcttt ctgtagtttg
     2641 attttatcaa aaatagtttt agacatacta tacgcattga aagatttgta caagaaagaa
     2701 gctcttatta cgatttttcc ttttattttt ataggcagga agaaagtaaa tgtgaggttc
     2761 tcgccctatt tttcattcca tcgtaaaagt ttgtcgcctg atgatttaag atctaggatt
     2821 atatggagtt ttattcttga aattgctatt atcctagtat ttattttaaa aattcctttt
     2881 gcaatcatca tgcttactac aatatttttc tggactataa tggatatcaa tcatctcgtt
     2941 tttaataaga cggaatttct tttcaatcaa aataaatggg aaaaagaaga ttcgtttgaa
     3001 agtgatttga caaatacgtt aaaggataaa atacaaaaat cagatctcag ttattctgac
     3061 ttaatgtctc ttcagctgta tgatgcgatg aatcaatcta cctttttaac ggatagtgaa
     3121 ctctttgagg atattctgag taaaattgaa gattctcata acacccttct gtgtacaggt
     3181 cttgtcgagt tactgctgta tgagatttct attagtaaca ataacaactg gtccaacaag
     3241 gttgataaaa ttaggataca cctcatcaga atcaatcaat tagatttttt ctattataca
     3301 agttggttaa ggcaaaattt tgatttctgt atgaatagag agtatcataa aatgaaatct
     3361 cggaaattat tactgagtaa taaaaagata gtttaagttc gtcctatttg taaaacaaat
     3421 gaaacaattt caactaagga ggagaaaaca aatggaactt gtattaccaa ataattatgt
     3481 tgtgattgat gaagaagaaa tgatgtatct tgatgggggg gcttatttaa gcaagagtga
     3541 ttgtcaagga atttgtgcag ctttagctat gagcccagga acttttatag cattagctgg
     3601 atctgcagtt ttaactaaaa aactaataaa ctatattaag tttggaggtc ttggaggctg
     3661 gcttattggt gcagcagcag gtgtattggc tacagcagca ggaaaaatag cttactgtat
     3721 tggatatggt gctcttaata gaggttgtga tattagcggg aacccttatc cttgggatgg
     3781 attcatatct gcgacagtaa gatgaataat gtagataaga ttcgaaaaat acatattatc
     3841 gtatgttgga tgtatatatt tttatcattc agggcgatta taaatgacac ggagtatttt
     3901 ttgcttattt ttttagcttt tatctactca atagtatcac tacctctata ttctgtgaaa
     3961 aataaaatag tatctatctg tctagccata aattcgattc tgttaatgag tttccccatt
     4021 ttaatcaata agtttttccc agaaagtttt ttgacttata ccgtattaat aagtgttttt
     4081 atcctagagt tagcaatctt tcatttaatt ggggaagatt ttgctactaa attgactaac
     4141 gaatataaga aaattagtca gtttagaagc aaggtgtctc aatctccttg gataaaatat
     4201 ttagagattt ctagttttat attaactata tttccatcta ttctttacgg tacagttgat
     4261 aatcgtgtat tggctcttat ctttttgata aaaatttgtg tagatactac gataaaattt
     4321 ttattcatca gattatttga cacaagtact ttaatgaaga ggagaatatt ttttcttttc
     4381 gcattggatg ttatagctta cttattttta ggatatcttt tagtgattca aaaagcaggc
     4441 tatttgtttt cggttttact tcttttttct aatttttcag ttccatttat caaagcaaag
     4501 gaatacgaat tatttaaaaa tagcaagtaa tagaaacata ggttaaatct tagaacggct
     4561 taaaatcaga tatgataaag ggaaatagtc ttatctaggt aactaagtgc tacaaacaca
     4621 gtcgaggatc acttgttagg attacatttt aatcatgctt aataagaatg gagaattcct
     4681 atggggattg tattactctg aagtttcgaa taccttagtt ctcgtgattt tgagctgttc
     4741 tagctttaga atccttcaga atgtaaaatt ttaagcagtc aaagacttag aatagcctgg
     4801 aaacatttat tttatagcaa ttctaggctt agaattgctc atatatatgt atttgagctg
     4861 ctcgatagtt aggacagctc tattctgaga aatctgagct atcaatgctt cagaatagta
     4921 tttcgcaaat ggtttttatt gaagaggtga ttgttttatg atagtctaaa ataaaactga
     4981 tttaatggag taaatggaga atcgtcacat gaaacatttt tttgcaggaa ttggtgagat
     5041 aaaacttgtt ggctacttat tgtatatatg tgtaggacta gcccctcttt ttcatatata
     5101 tgtcataggt tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttatatt
     5161 tgtaagtatg ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac
     5221 ttgaactgta tctaaaaaca gaggttggtc gattatcagc ctctttcttg tcgttgaaaa
     5281 gagtgagata tattgacttt tgaaaaaaat gtcataattg agttgggata aacctaaaag
     5341 taatatagta gattgaatct ggaatagtcc gttatgactg ttaaaatatt tctagaaatt
     5401 aatttgactt tcctaatcga tttgttcaca tcttgtttca atctactata ctttctcgtt
     5461 aaaccgttcg gcaattcatg gtgacatgga cacatagtag taagcacatt atgtggcttg
     5521 gcagagctaa aaactgttcc cttgcgataa gcctaataag cacaacatag ggagttagag
     5581 aagccgactc taatcaacca ctttgggcag tagtgagaac tgccccgtgc tttttatttt
     5641 gagaaaatat ggagtttgtc gttgaaatta cttgattgta ttttggacta tcaagaaaga
     5701 ttcaatggaa aaacatgtca agtatcaacg aattataagt atttagagac tttcaaagtg
     5761 aatttttgct tgactgattt acatcattta tttggcttac acaaaatcac acgagattat
     5821 gctagtcaaa caaaacctgc tattcaagat ggtgttttta ttttagaaga ttttagaaat
     5881 atcctattgt acaatgatgt aatcgaaagg atatctttat atgagtttat aggtgatatt
     5941 ttctattcta aaataacaag ttgttgcatc gtagctaagg atttatctaa aaatactatg
     6001 aaattggacg tcatattttt tgaggataaa aataaaagat ccgcagtttt aggtttacga
     6061 agagacaaaa gcggagtatt taaaccagtt accctacatt ttacaagcgc taagaaatat
     6121 gctaaagttc gtaaaacaga tgtgaaagaa atgaaatggc tataaagatt gtccgcaggc
     6181 ttaagcttgc gttttttgtt gtttaacgaa attaaaaaaa caagctctct catcggaaat
     6241 gtttttatag gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa
     6301 agtagtgtct ttatcttttt ggagtagaag cttatgatat agaaatttgt aataaaaatg
     6361 taatataaaa catttgacaa atatttacgg ggggagtata cttaatataa gtatagtcta
     6421 aaaatgacta tcagaaaaga ggtaaattta gatgaataag aaaaaaatga ttttaacaag
     6481 tctagccagc gtcgctatct taggggctgg ttttgttacg tctcagccta ctttggtgag
     6541 agcagaagaa gctcccgtag ctaaccagtc taaagctgag aaagactatg atgcagcagt
     6601 gaaaaaatct gaagctgcta agaaagatta cgaaacggct aaaaagaaag cagaagacgc
     6661 tcagaagaaa tatgatgagg atcagaagaa aactgaggag aaagcagagc ttgttcgaaa
     6721 agcggatgaa aaacgtcaaa aagcgaattt ggcagttcaa gaagcatatg taaaattcca
     6781 agaagcacaa agagaattta acgaaagtcc aagcagaaaa aaatctgatg ctaaaaagaa
     6841 attagatgat gcatcagctc atattgaaga ggtaaaatta aaacaaaaag aggcggatgc
     6901 gaattttaat aaggaacaag caaaagtaat tcccgaagca agtgacttag ctgttactaa
     6961 acaaaaagcg gaagaagcta aaaaagaagc agaagtagct aaggaaaaat atgataaggc
     7021 agttcaagag gtagaagtag agaaaaataa aatacttgaa caagatgctg aaaacgaaaa
     7081 gaaaattgac gtacttcaaa acaaagtcgc tgatttagaa aaaggaattg ctccttatca
     7141 aaacaaagtc gctgaattaa ataaagaaat tgctagactt caaagcgatt taaaagatgc
     7201 tgaagaaaat aatgtagaag actatattaa agaaggttta gagcaagcta tcgctgataa
     7261 aaaagctgaa ttagctacaa ctcaacaaaa catagataaa actcaaaaag atttagagga
     7321 tgctgaatta gaacttgaaa aagtattagc tacattagac cctgaaggta aaactcaaga
     7381 tgaattagat aaagaagctg cagaagatgc taatattgaa gctcttcaaa acaaagttgc
     7441 tgatctagaa aacaaggttg ctgaattaga taaagaagtt actagacttc aaagcgattt
     7501 aaaagatgct gaagaaaaca atgtagaaga ctacgttaaa gaaggcttag ataaagctct
     7561 tactgataaa aaagttgaat taaataatac tcaaaaagca ttagatactg ctcaaaaagc
     7621 attagatact gctcttaatg aattaggtcc tgacggtgat gaagaagaaa ctccagctcc
     7681 agcaccaaaa ccagagcaac cagctgaaca accaaaacca gcgccggctc ctcaaccagc
     7741 tccagcacca aaaccagaaa aaacagatga tcaacaagct gaagaagact atgctcgtag
     7801 atcagaagaa gaatataacc gcttgcccca acagcaaccg ccaaaagcag aaaaaccagc
     7861 tccagcacca aaaccagagc aaccagttcc tgcaccaaaa acaggttgga aacaagaaaa
     7921 cggtatgtgg tacttctaca atactgatgg ttcaatggct acaggttggc tccaaaacaa
     7981 cggttcatgg tattacctca acagcaatgg cgctatggct acaggttggc tccaatacaa
     8041 tggttcatgg tattacctaa acgctaacgg cgctatggct acaggttggg ctaaagtcaa
     8101 cggttcatgg tactacctca acgctaatgg tgctatggct acaggttggc tccaatacaa
     8161 cgattcatgg tattacctaa acgctaacgg cgctatggct acaggatggc tccaatacaa
     8221 cggttcatgg tactacctca acgctaacgg tgctatggct acaggttggg ctaaagtcaa
     8281 cggttcatgg tactacctca acgctaacgg ttcaatggca acaggttggg tgaaagatgg
     8341 agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat ggttcaaagt
     8401 atcagataaa tggtactatg tcaatggttt aggtgccctt gcagtcaaca caactgtaga
     8461 tggctataaa gtcaatgcca atggtgaatg ggtttaagcc gattaaatta aatcatgtta
     8521 agaacatttg acattttaat tttgaaacaa agataaggtt cgattgaata gatttatgtt
     8581 cgtattcttt aggtacctat cttatgattt caggaagtgt cattaaaaaa acgactcctt
     8641 ttctctaact tgaaaaatag attagagaaa atgggttgtt ttatttatta tagttatttg
     8701 aatgaagata agaagagggt atactcacgt cattcacatg atctgtatat tgactataag
     8761 ttttaaaaaa caatttttaa gctcttcctt gtcttctcta accaagcgtg ttataatgaa
     8821 tactgctcaa gcgaccttca atcgtgaagc acacacgacc ttcaatcgtg aataaacgaa
     8881 tagatggaga cttaccatga gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg
     8941 tggtgttgat tcgtcggtga cggctctttt gctcaaggag cagggctacg atgtgatcgg
     9001 tatcttcatg aagaactggg atgacacaga tgaaaacggc gtttgtacgg cgaccgaaga
     9061 ttacaaggat gtggttgcgg tggcagacca gattggcatt ccctactact ctgtcaattt
     9121 tgaaaaagag tactgggacc gcgtttttga gtatttccta gcggaatacc gtgcagggcg
     9181 cacgccaaat ccggacgtta tgtgcaacaa ggaaatcaag ttcaaggcct ttttggacta
     9241 tgccatgacc ttgggggcag actatgtagc gactgggcat tatgctcgag tggcgcgtga
     9301 tgaggacggc actgttcaca tgcttcgtgg cgtggacaat ggcaaggacc agacctattt
     9361 cctcagccaa ctttcgcaag aacaactcca aaaaaccatg ttccctttgg gacatttgga
     9421 aaagcctgaa gtacgcagac tagcagaaga agcaggcctg gcgactgcta agaagaaaga
     9481 ttcgacaggg atttgtttta tcggagaaaa gaactttaaa aacttcctca gcaactacct
     9541 gccagctcag cctggtcgca tgatgactgt ggatggtcgc gatatgggcg agcatgcagg
     9601 tcttatgtac tatacaatcg gtcagcgtgg cggactcggt atcggtgggc aacacggcgg
     9661 tgacaatgcc ccttggttcg ttgtcggaaa agatctaagc aagaatattc tctatgtagg
     9721 acaaggattc taccatgatt cgctcatgtc aactaaccta gaagccagtc aagtccactt
     9781 tactcgtgaa atgccagaag agtttacgct agaatgtacg gctaaattcc gttaccgtca
     9841 gcctgactct aaggtgaccg tccatgtcaa aggagacaag gcagaagtta tctttgcgga
     9901 accacaacgc gcgattacac caggacaggc agttgtcttt tacgatggcg aagagtgtct
     9961 aggtggcggt ttgattgaca atgcttaccg cgatggacaa gtttgtcagt acatttagat
    10021 tgacaaattt tctcaatttg ctacaataat aacagcaata gaaatgatgg tcaaagctca
    10081 tggatgttgc aggctttttt gtcctgcact tctttgtagt tttgactgtt tttgtgtcgt
    10141 ttaagggaaa ggacaagaat gactcaacaa gactttcgga caaaagtaga caatacggtt
    10201 tttggtgttc gggcgacagc cttgattgtc caaaatcaca agcttctagt caccaaagac
    10261 aagggcaagt attacactat cggcggtgcg attcaagtta acgaaaaaac ggaagacgcg
    10321 gtagtccgtg aagtgaagga agaactaggt gttaaagctc aagctgggca gctagctttt
    10381 gtggttgaaa atcgttttga agtggacggc gtttcctatc acaatatcga gtttcattat
    10441 ctggtggatt tgcttgaaga tgccccgttg accatgcagg aagatgagaa aaggcagccc
    10501 tgtgagtgga ttgacttgga taagcttgag gatatccagc tagttccagc ctttttaaaa
    10561 acagccctac cagattggga aggccaacta agacacattc atcttgagga ataggagaga
    10621 aacatgactt atcattttac tgaagaatac gatattattg taattggtgc gggacacgct
    10681 ggggttgagg cttccttggc cgctagccgt atgggctgta aggtcctgct tgcgaccatc
    10741 aatattgaaa tgctggcttt catgccttgt aatccctcta tcggtggttc tgccaagggg
    10801 attgtcgtgc gtgaagtcga tgccctcggt ggcgagatgg ccaaaaccat tgacaagact
    10861 tacatccaga tgaagatgct caacacaggg aaggggccag ctgtccgtgc ccttcgtgcg
    10921 caggctgaca aggaacttta ctctaaggag atgcgcaaga cggttgaaaa ccaagaaaat
    10981 ctgacccttc gtcaaaccat gattgatgag attttggtgg aagatggcaa ggttgtcggt
    11041 gtgcgtacag ccacccatca agaatatgct gctaaggctg ttattgtgac gacagggact
    11101 gctctccgtg gggaaattat catcggagac ctcaagtact catcaggtcc taaccacagc
    11161 ttggcttcta ttaacctagc tgacaatctc aaggaactgg gcctcgaaat cggtcgtttc
    11221 aagacaggaa cccctccacg tgtcaaggct tcttctatca attacgatgt gacagaaatc
    11281 caaccaggag atgaagcacc taatcacttc tcatacactt cacgtgatga ggattatgtc
    11341 aaggaccaag tgccatgctg gttgacctac accaatggta ccagtcatga gattatccaa
    11401 aacaacctcc accgtgcgcc tatgtttaca ggtgtggtca agggagtggg gcctcgttac
    11461 tgtccatcga ttgaggacaa gattgtgcgc tttgcggaca aggaacgtca ccaactcttc
    11521 cttgagccag aagggcgcaa tactgaggaa gtctatgttc aaggactttc aaccagtctg
    11581 cctgaggatg tccagcgtga cttggttcat tccatcaaag gtttggaaaa tgcagagatg
    11641 atgcggacag gttatgctat tgagtatgat atggtcttgc ctcatcagtt gcgtgcgact
    11701 ctggaaacca agaaaatctc aggtctcttc actgctggtc agacaaatgg aacatcaggt
    11761 tatgaagaag ctgctggcca agggattatc gcgggtatca atgcggctct gaaaatccaa
    11821 ggcaagcctg agttgatttt gaagcgcagt gacggttata tcggggtgat gatcgacgac
    11881 ttggtgacca agggaaccat tgaaccctac cgtctcttga caagtcgtgc tgaataccgt
    11941 ctcattcttc gtcatgacaa tgctgatatg cgcttgactg agatgggacg cgagattggc
    12001 cttgtggatg atgaacgctg ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag
    12061 atgaaacgcc tagacagtat caaactcaag ccagtcaagg aaaccaatgc taaggttgag
    12121 gaaatgggct tcaagccgtt gacagatgcg gtgacagcca aagaattcct tcgccgtcca
    12181 gaagtttctt accaagatgt ggtggccttc atcggaccag ctgcagaaga cttggatgac
    12241 aagattatcg aattgattga aacagaaatc aagtacgaag gctatatttc caaagccatg
    12301 gatcaggttg ccaagatgaa acgtatggaa gaaaaacgca ttccagccaa tatcgactgg
    12361 gatgacatcg attctattgc gacggaagct cgtcagaagt tcaaactcat caatccagaa
    12421 accatcggcc aagccagccg tatttcggga gtaaacccag cagatatttc tattttgatg
    12481 gtgtatctgg aaggtaaaaa tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatac
    12541 gtcgtcggct tcttacgaat gagttcaaag cttggctttg attcatctcc aacctcccat
    12601 agttccccga actatgggag ctaactcaag ttatgctttc gcttagcctt ctagtctgat
    12661 tttcattgag ttttaatctc aaaagaaagc atagagaaaa acagctccga agacggggct
    12721 gttttgttga tttgtactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt
    12781 gctcaaagca ctgctttgag gttgtggata gaactgacga agtcagctca aaacacagtt
    12841 ttgaggttgt ggatagaact gacgaagtca gtaacatata tacggcaagg cgaagctgac
    12901 gtggtttgaa gagtattatt cttcatctgg tgtgaggatc atcgggatga tgatcggttc
    12961 acgttcggta ttttcataga ggaaggggcg aatagcgttg acaatggcac cattgacaga
    13021 ttgcacgcta gcatccttat ttttcagtgc gatacgaatg gcattgaaga ggatacgctg
    13081 gctttggcga atcaagtcgc cagactctct catgtagaca aagcctcggc tgaggatgtc
    13141 tggaccagat agaatcatct gcgatttgaa gtcaacagtt gcgactgcca gaacgacacc
    13201 gtcttcagat agatcgcgac gatctttgag gacagctgcg ccaatttcac cgatacgatt
    13261 tccatcgaca tagatatctt gggcgttgaa atgacctgcg atacgagctg agtcagcagt
    13321 aagggcaagc acatcgccat tgctcatgat aaagatattg tccttctcaa caccagtatc
    13381 cactgctagt ccagcgtgga ctttttgcat gcggtattca ccgtggacag gcatgaagta
    13441 ttttggctta atcaagcaga gcatgagttt ttgctcttgc tgaccaccgt gtccagatgt
    13501 atggatattg tttactttac cgtggataac ttcgacacca gcttcagaaa tgatgttaat
    13561 cagcttgttg acgctagtag tgtttccagg gatgggacta gaagagaaga taacggtatc
    13621 acctggttgt aattgtactt gacggtgggt tccgttggcg atacgagaga gggctgccat
    13681 aggctcaccc tgactacctg tacagaggat aagaacttct cctgcaggat aatctttgat
    13741 ttcatttggc tcgataaagg ttcccttagg agctttgatg tagccaagat cgattccgtt
    13801 gacaatggcc ttttccatag aacgaccaaa gaccgcaatc ttgcgtccag tcttaacagc
    13861 agcttctgtt gcctgctgga gacggaagat atttgaggca aaggatgcaa agatgatacg
    13921 tccttcaata ccttggataa tcttcataat ggactgacca acgacttttt cagagttggt
    13981 aaaggttggt acttccgcat ttgtcgagtc agacaggaga cagagcacgc cttcttcacc
    14041 aagcgcagcc atacgatgca agtccgcagg ttctccaact ggagtaaagt cgaacttaaa
    14101 gtcacccgta cagacgattt tcccttgagg agtatgaatg acaatcccca aaggctctgg
    14161 aatagagtga gtcgttctaa agaaagttgc cttgagattt ttaaaggtca actcggtgtt
    14221 gtggttgatt tcgtaaagtt tggcgttgcg caagaggccg tgttcttcga gtttcccacg
    14281 gatcaaagcc aaggcaagcg gtccagcgta gatagggaca tttgcttgct tgagtaggaa
    14341 cggaatccca ccaatgtggt cctcgtgtcc gtgtgtgatt aaaacagcct tgacgcggtc
    14401 gatattgtcc acgatgtaag agtagtcagg aatgacatag tcgataccaa gcaagtcatc
    14461 ttctgggaat ttaatcccag catcgacgat gataatctcg tcttggtatt caattccgta
    14521 agtgtttttc ccgatttctc ctagaccacc gatggcaaaa acgccgactt cttcaggttt
    14581 aagagtgtag gccatattag aactccgtaa tttcgaaggc gccagtttct ttttcgtaat
    14641 cgagcaattt gtcagacaag agttcgatat attcgatatt gtactctggg cgattttctt
    14701 cgacaagttg gcgagcagtg atacggccct caagttctga gctggcatcg atgtctaggt
    14761 aaagcgcgcg tgttgtttca cggcgtgggc tacgttcttt tgtttcttga taaaaaactt
    14821 tgtaaatcat atagttcctt tctatttaca ggtcagctta ttccaaactt ttagcagaga
    14881 tttgcttgat ttcattccat tttgtgtcta gattgacctt gattcgttac aattatttca
    14941 attataccac aaaatgaaaa attagtaaaa gacggaaacg agaaagttag gggacgattt
    15001 ctttggtaag cgtttgcaaa aataaagaaa atgtattatg ttgataacgg aagtgaaatt
    15061 tattgcttgt cataattcca tatagatttt aagtcaagga ggttgcccta tgtataactt
    15121 atttgctttt gctatcggag ttcgtttgct agcttttatc gtttttgttg cttgcgttta
    15181 tggaggaaat cttctatttg ccaaactgga acgacgacaa accaagttct tgtggaaaat
    15241 gacctttgtg actctctact cgctttttct cctcctcgtg acctatgtcg tttggtttgt
    15301 attttacttt gaattaaatg cttagatgcc ctgcttatgc tggggttttt tgtttgggga
    15361 tgtagagata gtagatttac gacacgaaaa ttccacccca tctatcaaga tgaggtggtc
    15421 tttgcatttt tctaacatga catgacaatg gaattttcaa agcttattat ttttatggga
    15481 gtcattgttc tgatcaaaaa tagagttgaa gcataaaaat aaaacaatac aaacagataa
    15541 atcgaatggt aaagggatgg tagtaatgtt caaatcattg agaatgctga gcaaactgta
    15601 agagatgaag acaataaaat ttatccttct aaaaatgtgt ttcttatcta gcatgactta
    15661 ccaaactttt tacgaaggtc ttttccaatg gtataacctg ccataaataa agcgatacca
    15721 acaccgacac caaagccacc cttgatttct tgcaattcct tattagaaat ttcacgataa
    15781 ttgttcaaat ctttcatcat attaatctcc tcctaaaaaa taaccagctg ccaaaccaga
    15841 acctataagt gctgttccac ctgcaatagc cttccaagat actgctactc caaagataac
    15901 caagggagcg agaccgccat caatatctga taattcattt tcagataagg ataaaaattg
    15961 attgtcaaga atgtcaaaat ttgtcattga actttcctcc ttttttcttg ttcactttta
    16021 tattcggaaa agaaaaggaa aagtgagcat ttttttaaat tatttttagt taagtgaggg
    16081 cactcttgtc tgggggcaaa gaaaattccc atgtgccagc ttttgtagta taatagtaag
    16141 cagacaaaaa gataggaatg tgttatgaaa gtattagctt ttgatacgtc cagcaaggct
    16201 ctttctctgg ctattttaga ggataagcag gttcttgccg agacgacgat taatattaag
    16261 aaaaatcaca gtattactct tatgcctgcc atcgattttt tgatggcaag tttggattgg
    16321 acacccaagg atttggaccg aatcgtggta gctgaagggc cgggtagcta tacaggcttg
    16381 cgaattgcgg tagcaactgc taagacctta gcttacaccc tgaacatcga gttggttggt
    16441 atgtcgagtc tcttggctct ggtgccccac caacaagaag gtttgtttgt ccccttgatg
    16501 gatgcgcgtc gcaataatgt ttatgcagga ttttatgaaa atgccaaacc tgtcatggca
    16561 gaagcgcacc tatcttttga agaggtgcta gaaaaagtca agggtactag tcaggtaacc
    16621 tttgtcggag aagttggccc ctttgttgag cagattcaaa aacacttgcc aaggactgat
    16681 tacaaagaaa cattgcccaa tgcagccaat cttgctcttt tagcttggga caaggaagca
    16741 gactccttgc atgattttgt gccgaactac ctcaagcgtg tcgaagctga ggaaaactgg
    16801 ctcaagaatc acaccgagtc tggtgagtcc tacattaaac gcctatgata gaaatcaagc
    16861 gaattcaaca acatcctgac ctagctcaag ccatctacgc tgttatggca gctgtttacc
    16921 tagtcagtcc ttggactctg gagcaaatcc aagcagatct gtcccaagac cagacttggt
    16981 atgcattggc ttatgatggg gcagaagtga ttggatttct agctgtgcag gagaatcttt
    17041 ttgaagcaga agtcctgcaa atcgctgtca aaggagctta tcagggtcag ggaattgcgt
    17101 cagccttgtt tgctcaattg ccgacagaca aggaaatttt cctcgaagtc agacagtcaa
    17161 atcaacgagc gcaagcattt tacaagaaag aaaagatggc agttatcgct gagcgaaagg
    17221 cctactacca tgacccagtc gaggacgcca ttatcatgaa gagagaaata gatgaaggat
    17281 agatatattt tagcatttga gacatcctgt gatgagacca gtgtcgccgt cttgaaaaac
    17341 gacgatgagc tcttgtccaa tgtcattgct agtcaaattg agagtcacaa acgttttggt
    17401 ggcgtagtgc ccgaagtagc cagtcgtcac catgtcgagg tcattacagc ctgtatcgag
    17461 gaggcattgg cagaagcagg gattaccgaa gaggacgtga cagctgttgc ggttacctac
    17521 ggaccaggct tggtcggagc cttgctagtt ggtttgtcag ctgccaaggc ctttgcttgg
    17581 gctcacgaac ttccactgat tcctgttaat cacatggctg ggcacctcat ggcagctcag
    17641 agtgtggagc ctttggagtt tcccttgcta gcccttttag tcagtggtgg gcacacagag
    17701 ttggtctatg tttctgaggc tggcgattac aagattgttg gggagacacg agacgatgca
    17761 gttggggagg cttatgacaa ggtcggtcgt gtcatgggct tgacctatcc tgcaggtcgt
    17821 gagattgacg agctggctca tcaggggcag gatatttatg atttcccccg tgccatgatt
    17881 aaggaagata atctggagtt ctccttctca ggtttgaaat ctgcctttat caatcttcat
    17941 cacaatgccg agcaaaaggg agaaagcctg tctacagaag atttgtgtgc ttccttccaa
    18001 gcagcagtta tggacattct catggcaaaa accaagaagg ctttggagaa atatcctgtt
    18061 aaaaccctag ttgtggcagg tggtgtggca gccaataaag gtctcagaga acgcctagca
    18121 gccgaaatca cagatgtcaa ggttatcatc ccccctctgc gactctgcgg agacaatgca
    18181 ggtatgattg cctatgccag cgtcagcgag tggaacaaag aaaactttgc aaacttggac
    18241 ctcaatgcca aaccaagtct tgcctttgat accatggaat aaagagtggc tctttgtcaa
    18301 gtgtagtggg taggcgaaaa gctacaatct ggagagtacg aaattcgtac tctctttttt
    18361 gatgttcaaa gtcatcaaaa tccgtttttt aaaattgtta aagttccgga aaccaaaggc
    18421 tttgcgcttg ataaccttaa tcaaattatt ggtcgcttca agtttagcgt tggaataagg
    18481 cagcttaagt gcgttgataa tcttatctct atcccttaaa aaagtccaaa agaccgtttg
    18541 aaaaagcgga tgaaccgttg gcagttcttg ctcaatcaat ccaaagaaat ggtcggcatt
    18601 cttctcttga aaatgaaaga gcaggagttg atagagttcg tagtaaacct gtaatccctc
    18661 agagtaagaa agcagcttat ctcgtacttc ccgatgggtt aagtgcattc gaaacgtggg
    18721 ctgatagaat cgtttctgac agagcttgaa gctatcctgg tgtagtaaat cagtccagtg
    18781 gactgattta gcccgagcct agaaacgaaa aagcgagggt tccaaaagcg cttgagcgcc
    18841 cgatactcca aggattttcg gtcaaattgg ttcatgattt ggattcgtac tcggttcata
    18901 gctcggctca gatgttggac aatgtggaag cggtcaagaa caatcttcgc ctttggaaag
    18961 agttgcttag cgagccgata ataagggctg tacatgtcca tggtgatgac ctcgaccagc
    19021 tcccgaacct ctctctgata gcgttggaaa tggtttcgaa tcaccgcatg agttcgcccg
    19081 tctaaaattg cgaggatgga tttggactca aaatcttggg caatgaagct cattttgctc
    19141 tttttgaagc tatactcatc ccaactcata acttttggca acttggtcca atcggtttca
    19201 aacttaaatt ccctcagttt tcggatgacg gtggaagttg agaccgccaa tctgtgggca
    19261 atctcagtca tagactgctt ttcaaggagg agctgagcga ttttttgtct caccatgttg
    19321 gaaatctggc aatttttctt gacaatggat gtttgagaaa cgaccacctt aaggcaattc
    19381 ttgcactgaa agcggcgctt tttgagatgc agtaccgtgg gtaaaccctg acagtcgaga
    19441 agcggaattt tagaggcttt ctggaagtcg tatttgatca tcttcccttg acaatgagga
    19501 caaggaggag cgggggaatc caactttgcc tgaacgacta gatgggtttg gtatttcaga
    19561 acagacaaga ttttgatatt tttgtcttcc aatccgagca aatctgtggt attcttaagt
    19621 tgttccatat gaaccctttc taatgagttg gttagacgct tttcattata ggtcatatgg
    19681 ggcttttttt ctacaagaaa cgaccctata attcctgggg tgggattacc cactacagaa
    19741 attatagagc caaagcattc caaagtcttg tctgactctg gaatgttttc tgttcacagt
    19801 tgttttgtaa ctgcctaata agtaaccgcg ctataacgag gtatctaccg agattgtcaa
    19861 ttctccagta tactgttata aaaaacaaaa ctggaggatt tttttatgtc cccccatcgt
    19921 cccatcgact gttccgtagc tgcccaataa cggagtatag tcggctgaaa caagaatagg
    19981 acaaaagtgc ctcaagaaaa gcatcgtaat ttgacaatat tattctgaga tgtttttgat
    20041 gtaagcccat attttctcaa tgggattata ctcgggtgaa taggtaggaa gtggtaacag
    20101 tctatgccct gctccttaca catgttcatt ctgtgaaacc ttgcattgtc cataatgata
    20161 agggatggtg tatctaaagt aggtagtaag aatttttgga agcaagcttc gaaggagcca
    20221 tagtatattg aaacaaaaaa gggcattagt acttctataa cagtatcgca atctctggtg
    20281 tgcgttgtct cgatcttaat tcaaataatt atatcttctt ccagagagac taactgcctg
    20341 ctcaaggctc gatcatattc gagataaaaa taggtcttaa cccctgtctc ataaatataa
    20401 ataggagtca ggtagcttaa gtgattcaat tctttaagga accgatttac tttttctggg
    20461 tcttgttcgc agtaggtacg gctctttttt agactatatc ccatagcctt tagagcgtaa
    20521 tgaatagttg ttggaggaca gttgaattca gcagctattt cagtcaaata agcatcggga
    20581 tgagtttcaa tatagatctt taatttatct ctatcaactt tttcaattaa tagtggaagt
    20641 tttcttgaag ttagtgtatt gaaacgtttt tatacagtgc taaaatttga agtgtagtgc
    20701 agatgtattt gtaatagtat tatagcaatt ctttggagaa ggtcgagaca agagaaaata
    20761 ggtatctttg agatataagc atgatttact ataaaattat tgagttattc ataaaaattt
    20821 ctctatcaaa tatcataatg cgtcgtttaa ggagatggtt acaatgcaat atagttgtgg
    20881 aaaaataaat attaatatcc ctgatggata tggagacatt aaggatatag tgttttcggc
    20941 tcatattata gttaggtata ataatggaca ttgtggaggt atagatccgc atataattgg
    21001 actttgtaaa aagcagatca gaaggatgtc tctatatcct attttgataa tcgtatctag
    21061 agattcaaag gttattgatg attataaaaa tttagatatt gcctatgttg attgtactca
    21121 atgttcaaat aattttgaaa ctgccttaca cgttaaaaat at
//
LOCUS       DAVLBN010000036        20872 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLBN010000036 DAVLBN010000000
VERSION     DAVLBN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.036"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            168..665
                     /locus_tag="VXC24_001348"
     CDS             168..665
                     /locus_tag="VXC24_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0493455.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            665..2320
                     /gene="dnaX"
                     /locus_tag="VXC24_001349"
     CDS             665..2320
                     /gene="dnaX"
                     /locus_tag="VXC24_001349"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0493456.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2348..2542
                     /locus_tag="VXC24_001350"
     CDS             2348..2542
                     /locus_tag="VXC24_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0493457.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2692..3462
                     /gene="sufC"
                     /locus_tag="VXC24_001351"
     CDS             2692..3462
                     /gene="sufC"
                     /locus_tag="VXC24_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0493458.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3490..4752
                     /gene="sufD"
                     /locus_tag="VXC24_001352"
     CDS             3490..4752
                     /gene="sufD"
                     /locus_tag="VXC24_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0493459.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4763..5989
                     /locus_tag="VXC24_001353"
     CDS             4763..5989
                     /locus_tag="VXC24_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0493460.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5976..6416
                     /locus_tag="VXC24_001354"
     CDS             5976..6416
                     /locus_tag="VXC24_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0493461.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6470..7882
                     /gene="sufB"
                     /locus_tag="VXC24_001355"
     CDS             6470..7882
                     /gene="sufB"
                     /locus_tag="VXC24_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0493462.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8113..9354)
                     /locus_tag="VXC24_001356"
     CDS             complement(8113..9354)
                     /locus_tag="VXC24_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0493463.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9457..10566
                     /locus_tag="VXC24_001357"
     CDS             9457..10566
                     /locus_tag="VXC24_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0493464.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11100..11447
                     /gene="ssrA"
                     /locus_tag="VXC24_001358"
     tmRNA           11100..11447
                     /gene="ssrA"
                     /locus_tag="VXC24_001358"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11620..11707)
                     /locus_tag="VXC24_001359"
     tRNA            complement(11620..11707)
                     /locus_tag="VXC24_001359"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11671..11673),aa:Ser,seq:gga)
     gene            11870..12610
                     /locus_tag="VXC24_001360"
     CDS             11870..12610
                     /locus_tag="VXC24_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0493465.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12607..13518
                     /gene="pfkB"
                     /locus_tag="VXC24_001361"
     CDS             12607..13518
                     /gene="pfkB"
                     /locus_tag="VXC24_001361"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0493466.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13515..15467
                     /locus_tag="VXC24_001362"
     CDS             13515..15467
                     /locus_tag="VXC24_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0493467.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15631..17856
                     /locus_tag="VXC24_001363"
     CDS             15631..17856
                     /locus_tag="VXC24_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0493468.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17901..18329)
                     /locus_tag="VXC24_001364"
     CDS             complement(17901..18329)
                     /locus_tag="VXC24_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493469.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18467..19609
                     /locus_tag="VXC24_001365"
     CDS             18467..19609
                     /locus_tag="VXC24_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0493470.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19618..20832
                     /gene="thiI"
                     /locus_tag="VXC24_001366"
     CDS             19618..20832
                     /gene="thiI"
                     /locus_tag="VXC24_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0493471.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
BASE COUNT         6120 a         3907 c         4645 g         6200 t
ORIGIN      
        1 tcgcttttca ttatagatct tatgggactt tttttctaca ataaaatagg ctccataata
       61 tctatagggg ggttacccac tacaaatatt atagagccca aaatcctttg tttactaaac
      121 aagggatttt tcttttgtct ctgctccttt tttgatataa tagttctatg ttaaaatcag
      181 aaaaacaatc acgttatcaa atgttaaatg aagaattgtc cttcctattg gaaggcgaaa
      241 ccaatgtttt ggctaatctt tccaacgcca gtgctctcat aaaatcacgt tttcctaata
      301 ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt ggttttaggc cccttccaag
      361 gaggtgtttc ctgcatccgt attgcactag gcaagggtgt ttgtggtgag gcagctcact
      421 ttcaggaaac tgttattgtt ggagatgtga cgacctatct caactatatt tcttgtgata
      481 gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta cttggagttc
      541 tggatctgga ttcttcagag attgaggatt acgatgctat ggatcgagat tatttggaac
      601 aatttgtcgc tattttgctt gaaaagacaa catgggactt tacgatgttt gaggaaaaat
      661 cttaatgtat caagcacttt atcgaaaata tagaagtcaa aacttctccc agttagttgg
      721 tcaagaagtt gtggctaaga ctcttaaaca agcggtggag caagagaaaa taagtcacgc
      781 ttatcttttt tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa
      841 ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc aataactgct atatttgtca
      901 agcagtgacg gacggtagtt tagaagatgt cattgaaatg gatgcagctt ctaataatgg
      961 ggtagatgaa attcgcgaaa ttcgtgataa atctacctat gcgcctagcc ttgctcgtta
     1021 taaggtttat atcatagatg aggttcacat gctgtctaca ggggctttta atgccctcct
     1081 aaagacgctg gaagaaccaa cacagaatgt agtctttatt ttggccacta ctgaattgca
     1141 caagattcct gctactattc tatcccgtgt gcaacgtttt gagtttaaat caattaagac
     1201 acaggatatt aaggaacata ttcactatat cttagaaaaa gaaaatatca gttctgaacc
     1261 agaggctgtg gaaatcattg ccagacgggc ggaaggtgga atgcgggacg ccttgtctat
     1321 tttggatcaa gccctgagtt tgacacaggg aaatgagctg acgactgcta tctctgaaga
     1381 aattactggc accattagcc tatcagcctt ggatgattat gtggcggcct tgtctcaaca
     1441 ggatgttccc aaagctttgt cttgcttgaa tcttcttttt gacaatggta agagcatgac
     1501 tcgttttgtg accgatcttt tgcactattt aagagacttg ttaattgttc aaacaggggg
     1561 agaaaatact catcatagtt cagtctttgt agaaaatttg gcacttcctc aaaaaaatct
     1621 gtttgaaatg attcgcttag caacagtgag tttagcagat attaagtcta gtttgcagcc
     1681 caagatttat gctgaaatga tgaccgtccg tttggcggaa atcaagcccg aaccagctct
     1741 atcaggagcg gttgaaaatg aaattgctac gctgagacag gaagttgccc gtctcaaaca
     1801 agagctttct aatgtaggtg cggttcctaa acaagttgca ccagctccta gtcgaccagc
     1861 tacggacaaa acagtctatc gtgtcgatcg caataaagtg caatctatct tacaagaggc
     1921 cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga
     1981 ggtaattgaa agtctaggtg ggccggacaa ggctctgcta gttggttctc aaccggttgc
     2041 tgccaatgaa caccatgcta ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat
     2101 gaaacgagac aatctcaata ccatgtttgg taatatcctc agtcaggcgg caggtttttc
     2161 acctgagatt ttagctattt ccatggagga atggaaagaa gttcgcgcag ccttttcagc
     2221 caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa agcctgattc cagaaggatt
     2281 tgaatttttg gctgataaag tgaaggtaga ggaagactaa agaaagattt catgatacaa
     2341 taagtttatg aataaacaac aatttattat tatggcgctg tttacagctg ctgagaccta
     2401 ttttttcaat gaagcctgga tgactggccg ctatattatg gcagcctttt gggcaatttt
     2461 actctttaga aatttccgag tcagttatgt gatgggcaaa atcgttgatg tcatcgatca
     2521 gcattttaat aggaaagact agccctcagc ttccagacaa aatcaaagcc ttttaggctt
     2581 ttttttgtta tactagaaaa gtatatttat agaatttttg ctctatttct ggggaaatca
     2641 gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta
     2701 ttagagatta aagatcttca cgttgagatt gaaggaaaag aaattttaaa aggggttaac
     2761 ctgaccctga aaacaggaga aattgccgct atcatgggac caaatggtac aggtaaatcg
     2821 actctttctg ccgctatcat gggaaatcca aactatgaag taactaaagg tgaagttttg
     2881 tttgatggcg taaacatcct tgagttggaa gtggatgagc gtgcgcgtat gggacttttc
     2941 cttgctatgc aatacccatc agaaatccct ggaattacca atgctgagtt tcttcgtgcc
     3001 gctatgaatg cgggtaaaga agatgatgag aagatttcag ttcgtgagtt tattactaag
     3061 ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa tggcagagcg ttacctcaac
     3121 gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt gatgttggag
     3181 ccaacatttg ctcttttgga cgagattgac tcaggtcttg atattgacgc tcttaaagtt
     3241 gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat catcactcac
     3301 taccaacgtc ttttgaacta tatcacacct gatgtggtac acgtgatgat ggaaggtcgt
     3361 gttgtccttt ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa
     3421 ttagctgaag aacttggcta cgactacaag gaagaattgt aatttcctcg tatcttttag
     3481 gagaagtaaa tgactagaga aaatattaaa cttttttcag aaatgcacgc tgaaccaagc
     3541 tggttggctg atctccgtca aaaagctttt gacaagattg agactttgga attaccagtt
     3601 attgagcgtg tcaaattcca ccgttggaat ctgggtgatg gaacgattac agaaaatgag
     3661 ccatcagcaa atgttccaga tttcacagct ttagatcatc acttgaagtt ggtgcaagta
     3721 ggaactcaaa ctgttttcga acaaactcca gttgagttag ctgaacaggg tgttgtcttc
     3781 acagactttc actcagcttt agaagaaatt ccagagctga tcgaagaatt cttcatgtca
     3841 tctgttaagt atgatgatga caagttggcg gcttaccaca cagcttactt taacagtggt
     3901 gctgtactct atattccaga taacgtagaa atcacagagc caattgaagg aattttctac
     3961 caagatagcg atagcaatgt gccgtttaac aagcatatta tgattatcgc tggtaaaaat
     4021 tctaagatta gttatctgga gcgtttagag tcacgcggtg aaggaagtga caaagtaact
     4081 gccaatatca cagtggaagt gattgcacgt tctggtgcgc aagtcaagtt tgctgctatc
     4141 gaccgtctag gtgaaaacgt cactgcctac attagccgtc gtggtaaatt aggcaacgat
     4201 gcaagtattg actgggctat cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat
     4261 agtgacttga ttggtaatgg tagccatgct gacctcaagg ttgtagctct ttcaagtggt
     4321 cgtcaggtac aagggattga tactcgtgta actaactatg gctgcaactc tatcggaaat
     4381 atcctacaac atggggttat ccttgaaaaa gcaactttga ctttcaatgg tatcggccac
     4441 atcatcaagg gtgctaaggg agcagatgcg caacaagaga gccgtgttct catgctttca
     4501 gaccaagcgc gttcagatgc taacccaatt cttttgattg atgaaaatga tgtcactgca
     4561 ggacacgcag cgtctatcgg acaagttgat ccagaagaca tgtattacct catgagtcgt
     4621 ggattggata aggcaactgc agagcgtttg gttgttcgtg gtttccttgg atctgttatc
     4681 gtggagattc cagtcaagga agttcgtgat gaaatgattg caactatcga agagaaattg
     4741 tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg attcgcaagg attttccaat
     4801 tttagatcag attgtcaatg atgaacctct ggtctatctg gacaatgctg cgacgacaca
     4861 aaaaccccta gtagttctga aagctattaa cagttactat gagcaggaca atgccaatgt
     4921 tcaccgtggt gtccatacct tagcggaacg agcgacagct ttttatgaag ctgctcgtga
     4981 aaccattcgt aagtttatta atgcaggctc tacaaaggaa gttctcttta ccagaggaac
     5041 gacaaccagc cttaactggg tggcacgctt tgctgaggaa attctcactg agggagacca
     5101 ggtcttgatt tcagtaatgg aacaccattc taatatcatt ccatggcagg aagcttgtcg
     5161 aaagactgga gcagagcttg tctatgtcta tcttaaagac ggtgccttgg atatggagga
     5221 tttgcgagct aaattgactg ataaggttaa atttgtttcc ctagctcatg cctccaatgt
     5281 tcttggtgtg atcaatccga tcaaggaaat cactcaatta gcccaccaag ttggggcaat
     5341 catggtagtg gatggtgctc aatctacacc tcatatgaag attgatgtcc aggacttgga
     5401 tctggacttt ttcgcctttt cgggtcacaa gatggctggt ccgactggta tcggtgtcct
     5461 ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta gaatttggcg gcgagatgat
     5521 tgattttgtc tacgagcaat ttgctagttg gaaggaattg ccttggaaat ttgaggctgg
     5581 aacgccaaat atggcaggag ctattggact tgcgactgca gttgattatt tggaaaagat
     5641 tggtatggat gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct atccaaaact
     5701 gcaggcaatt gagggattga ccatttacgg ttctcaggat ttggctcaac gttcgggtgt
     5761 tattgccttt aacctaggtg atctccatcc tcacgatctt gcgacggctc tggattatga
     5821 aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt
     5881 cccagcaaca gctcgtgcaa gtttttatat ctacaatacc aaggcagatt gcgacaaact
     5941 agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc actttctaaa ctagatagcc
     6001 tttatatggc agtggtagca gaccattcga aaaatccaca tcaccaaggg aagttagaag
     6061 atgctgagca aatcagtctc aacaatccga cttgtgggga tgtcatcaac ctctctgtca
     6121 agtttgatgc agaggaccgt ttggaagata ttgcttttct aaattcagga tgcacgattt
     6181 caactgcttc tgctagtatg atgacagatg ccgttttagg aaaaaccaaa caagaaattt
     6241 tagaactggc gactattttt tctgaaatgg ttcaagggca aaaagatgag cgtcaaggcc
     6301 aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg
     6361 caaccctagc ttggaatgcc cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca
     6421 agtttctttt gtcttatgaa ttattagaaa tgaagaaaga aaggatacta tggctgaaga
     6481 aagagtagaa ccaaaaccaa ttgaccttgg tgaatataaa tttggtttcc atgacgatgt
     6541 agagcctgtc ttatcgacag gaaaaggact caacgaaggt gttattcgtg aattatctgc
     6601 tgctaagggt gagcctgagt ggatgttgga gttccgtttg aagtcttatg aaaccttcaa
     6661 aaaaatgccc atgcaaactt ggggagcaga cttgtcagag attgactttg atgacttaat
     6721 ctactaccaa aaaccatctg acaaaccagc ccgttcttgg gatgatgtac ctgaaaagat
     6781 taaagaaacc tttgaacgta tcgggattcc agaagctgaa cgtgcttatt tagcaggggc
     6841 ttctgcccag tacgagtcag aagtggttta ccacaacatg aaggaagagt tccaaaaatt
     6901 aggtattatc tttacagata cagattccgc actcaaggaa tacccagact tatttaaaca
     6961 atactttgcg aagttggtac cgccgacaga taacaagttg gcagccctca actcagcagt
     7021 atggtcgggt ggaactttta tctacgtgcc aaaaggtgtc aaggtagata ttccacttca
     7081 aacttatttc cgtatcaata acgaaaatat aggtcagttc gaacgtacct tgattatcgt
     7141 tgatgaggga gcaagcgtcc actacgtaga aggatgtaca gcaccaacat attcaagcaa
     7201 tagcttacac gctgccattg tagaaatttt tgctttggac ggagcttata tgcgttatac
     7261 aactatccaa aactggtctg ataacgtcta taacttggta acaaagcgtg ctaaggctca
     7321 aaaggatgcc actgttgagt ggattgatgg aaacttgggt gccaaaacga ctatgaaata
     7381 tccatctgtt taccttgatg gagaaggagc gcgtggtacc atgctctcta tcgcctttgc
     7441 taatgcaggg caacaccaag acacgggtgc taagatgatt cacaatgctc cacataccag
     7501 ctcgtctatt gtgtctaaat ccatcgctaa aggtggagga aaggttgact accgtggaca
     7561 agtcaccttt aacaagaact ctaagaaatc tgtttcccac attgaatgtg ataccattat
     7621 catggatgac ttgtcagcat cagatactat tccatttaat gaaattcaca actcgcaagt
     7681 ggctttggaa cacgaagcca aagtatctaa gatttcagaa gagcaattgt attatctcat
     7741 gagccgtgga ttgtcagaat ctgaggcaac tgaaatgatt gtcatgggat ttgtagaacc
     7801 ctttacaaaa gaacttccaa tggaatacgc agttgagctg aaccgcttga ttagctatga
     7861 aatggaggga tcagttggat aaaatttgat tttatactct tcgaaaatct cttcaaacca
     7921 cgtcagcatc gccttaccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc
     7981 aaaacagtgt tttgagcaag ctgcggctag cttcctagtt tgttctttga ttttgagtat
     8041 tagatttact caaaatcaag gattttgaag atgaacttgt atcaaaaaat cgcggtttaa
     8101 aatcgcgatt ttttataatt tctcgttaac aaagcggaca aactgattcc accaaacttt
     8161 taagaagaag gctttttcaa ttttcttgtc tgctaccatt tcgaaactag ggcgctctgt
     8221 ggtgatgtaa ccttgaccaa tcaagtcctt gtcttcataa gtcaaatggc caaccactgt
     8281 tccagcttca agtggtgctg ggattgcttt ggaatcaggt gtgaattgaa cagattggga
     8341 agattgattc ccaacacgtt cgattagata gatatcctct ggagccactg cagttactgt
     8401 atcttctttt ccatcttgta caggggtttt gctatcttga taggcatcgc cttgttgaac
     8461 gattttgcga agtgtaaatg tagaagaaat ataatccatt agggaagatg tagctgtaaa
     8521 tcgagcgtaa ggattattgt cttgatgatc tgcatttaaa acaactgtga tgactctcat
     8581 gcctttttcg acagtagtac caacaaaaga ctctccagcc ttatctgttg ttcctgtttt
     8641 tagcccatca aaaccaccac ggtaagcagg cataccttct aacatgtagt tggttgaagt
     8701 gattgtcatc ccagcaaaag tagaagaagg ttttttggtg atttctaaga cttgtgggta
     8761 ttttttgatg aggttgcgag caacgatagc gacatcataa gcactaagct tattttcctc
     8821 atctttttta gaacctgggt aaatgttatc ccctagagtt tcattgttaa gacctgtcgt
     8881 attgacaaca gtggcatcct gaattcccca ttccaagagt tttgcccgca tcatatcgac
     8941 gaaatctttt tctgagccag caattttctc agctagggca atagcggcgc tgttggcact
     9001 agataccaga gttgcttcaa gcaactcttc gacagtataa ttacgggcct ccataggaat
     9061 attactggct tcagaatttg tcgtcaattg ataaggataa tcagaaatat ctacaggagt
     9121 ggagagggta atacttccgt tttccaaagc ttcatagacc agataaacag taatcaattt
     9181 tgttatggaa gcaatttcga caggttgcgt tgcatccttc tcatagagaa ttttaccagt
     9241 atttgcctca acagcaatcg catgtttagc ggcaatggta aaatcttgag caacagcagt
     9301 agaagcaccc cctaaaagag agacagttaa caaagttaaa aatatttttt tcatagtagt
     9361 cttattctat cataaagaaa aaaaatattc ttgctttaat aattcatctg ttaagctttt
     9421 tgaaaatatg gtaaaataaa gtgagggagg taactcatgt ttcgtagaaa taaattattt
     9481 ttttggacca cagaaatttt actcttaacc atcatctttt acctatggag acagatggga
     9541 tctttgatta acccttttgt tagcgtgctt aatacaatta tgattccatt tttattaggg
     9601 ggctttcttt attatttgac aaaccctatt gttactttct taaataaagt ctgtaaactc
     9661 aatcgtttgc ttggtatttt aattaccttg tgtactttgg tctggggaat ggtcataggt
     9721 gttgtctatc tcttacctat tttgattaat cagttatcta gtttgattat atctagtcaa
     9781 actatttata gtcgagtaca agacttaatc atagacttat ctaattatcc tgcgctccag
     9841 aatttggatg tagaagctac aattcagcag ttaaacttat cctatgttga tattcttcaa
     9901 aatatcctaa atagcgtatc aaatagtgtg gggagcgtct tgtcagctct tatcagtact
     9961 gttttgattt tgattatgac tccagttttt ttggtttatt tcttattaga tggacataaa
    10021 ttcttgccca tgcttgaaag aacgattcta aagagggatc gcttgcatat tgcaggctta
    10081 ttaaagaatt taaatgcgac gattgctcgc tatattagtg gagtttcgat tgacgcaatc
    10141 attataggtt gtttggctta tattggctat agtattattg gtttaaaata tgctttagtt
    10201 tttgccattt tttctggtgt agccaattta attccttatg tggggccaag tattggtttg
    10261 attcctatga tcatcgcaaa tatattcact gatccccata gactgctgat tgcagtgatt
    10321 tatatgcttg ttgttcagca ggtagatggc aatatcttat atcctcgaat cgtaggaagt
    10381 gttatgaagg ttcatccaat cacgatttta gttttacttt tgttgtcaag caatatctat
    10441 ggtgtagttg gaatgattgt cgcagtgcca acctattcta tcttgaaaga aatttctaag
    10501 ttcttatccc gtttgtatga aaatcataaa ataatgaaag aacgagaaag agaattagct
    10561 aagtaaaagt caggagaacc ctgatttttc tttactggaa gtggccttta gattagaaga
    10621 ctgaaaataa gttaaagtct taaactaatt ttcacagcta agaatagtag aagttaatct
    10681 gataaaaatc gaaaaaacca gtggaattct gtgtcagggt aagttccact ggttttcata
    10741 gtctattaaa gttcgaatga aacctattta tagtagattg aaactagaat agtacacctc
    10801 taattctaaa acattgttag aaatcgattt gactgtcctg atctattcgt cctattctta
    10861 tttcatttta ctatattttg gtgcaataag tgaaaagtag accgaataat ataaggattg
    10921 attttatagt ttttaaactc aaatgaattg aaataaagag agtacgaaaa ttctcatctg
    10981 aaagtatttt agaataattc tcttcgtgaa tttcttcaaa acagatagct tcatcttagg
    11041 tatgtgattt ctttttgcat ttttgagtta gataaggtat aatggtttta ttgtcttttg
    11101 gggtcgttac ggattcgaca ggcattatga ggcatatttt gcgactcgtg tggcgacgta
    11161 aacgctcagt taaatataac tgcaaaaaat aacacttctt acgctctagc tgcctaaaaa
    11221 ccagcaggcg tgacccgatt tggattgctc gtgttcaatg acaggtctta ttattagcga
    11281 gatacgatta agccttgtct agcggtttga taagagattg atagactcgc agtttctaga
    11341 cttgagttat gtgtcgaggg gctgttaaaa taatacataa cctatggttg tagacaaata
    11401 tgttggcagg tgtttggacg tgggttcgac tcccaccggc tccattattc ctttgcattc
    11461 cttggtaaaa cgttgttaaa tcaacgtttt ttatttttat ctttggtatt cctttgcatt
    11521 cttttgctaa aaagggagtc acaaacagac cctattttaa aaaaaggata gaaaaaagga
    11581 tacaacattt gtcgcatcct aaaaataatc ttttttcgac ggaagacatg ggattcgaac
    11641 ccacgcacgc tattacacgc ctaccgcgtt tccaacacgg cctcttaagc ctcttgagta
    11701 atcttccaat acttactcaa atagtctacc ataaaggctc ttatcttgca ataaaaattc
    11761 tagaaataag aaaaaatgat agattttgaa agaaaatgat aaaaaatgct tgacttcgaa
    11821 agaaagtatg atagaatgaa tagtgtaaac gataacagga ggtgattcag tgttaaaaac
    11881 agaacgtaaa caactaattt tagaggagtt aaatcagcat catgtagttt ctctagaaaa
    11941 attagttagt ttgctagaaa cgtcagaatc aacggttcga agagacttgg atgagttgga
    12001 agcggaaaac aagcttcgtc gtgtgcatgg tggagcagaa ctcccccact ccttacagga
    12061 agaagaaacc attcaagaaa aatctgtcaa aaaccttcaa gaaaagaagt tgctggctca
    12121 gaaagcagcc tctctcatta aagaaaaaga tgtcatcttt atcgatgctg gaacaacaac
    12181 tgcttttttg attcatgaat tggtcaataa gaatgttaca gttgtgacca actccattca
    12241 ccatgccgct cagttggttg aaaagcagat tccaactgtc atggttggag gaaacgtcaa
    12301 gacggcgaca gatgctagta tcgggggcgt tgctcttaac cagattaacc aattgcactt
    12361 tgaccgtgcc tttatcggaa tgaatggtgt tgacgatggc tattatacga ctcctgatat
    12421 ggaggaggga gctgtgaaaa gagctatttt ggagaatgcc aagcagacct acgtcttggt
    12481 ggattcgtca aaaattggac aaacttgctt tgccaaggta gcaccactca aacgcgctat
    12541 cgttatcact agtcaagggc atgagctctt gcaggttatt aaggagaaaa cggaggtaat
    12601 agaagtatga tttatacagt cacactcaat ccatccattg actatatcgt tcgtttggac
    12661 caagtcaaag ttggtagtgt caatcgtatg gacagtgatg ataagtttgc tggtgggaaa
    12721 ggaatcaatg tcagccgtgt cttgaaacgt ttgaatatac caaatacagc gacgggattt
    12781 atcggtggct ttactggtaa atttatcaca gatactctag cagaggaaga aatcgagaca
    12841 cgttttgtcc aagtggcaga agatactcgt atcaatgtta aaatcaaagc agaccaagaa
    12901 acagaaatca acggaacggg tccaactgtt gaaccggttc agctagaaga attgaaagct
    12961 attttatcta gtctgacagt agaagataca gttgtctttg caggttcaag tgctaaaaat
    13021 ctaggcaatg ttatctataa ggatttgatt tccttgacgc gccagactgg tgcgcaagtg
    13081 gtctgtgact ttgaaggaca gaccttaatt gatagtttgg actaccagcc tcttcttgta
    13141 aaaccaaaca atcatgaact tggagcgatt tttggggtta aactcgaaag tttagatgaa
    13201 attgagaaat acgctcgtga gttactggct aagggtgctc aaaatgttat tatctctatg
    13261 gctggtgatg gcgcccttct tgtcacatct gagggagctt acttcgctaa accaatcaaa
    13321 ggaacagtca aaaattcagt tggagctggt gattctatgg ttgctggatt cacaggtgaa
    13381 tttgtcaaat caaaagacgc agtagaagcc ttcaaatggg gagtggcttg cggaacggca
    13441 actaccttct cagatgactt ggcaacggcg gaatttatta aagaaacata tggaaaagtt
    13501 gaggtagaaa aaagatgaaa attcaagacc tattgagaaa agatgtcatg ttgctagatt
    13561 tgcaggcaac tgaaaaaaca gctgtcatcg acgagatgat taaaaatttg acagagcacg
    13621 gttatgtaac agattttgaa acatttaaag aaggaatttt ggcgcgtgaa gctttgactt
    13681 ctactggttt gggtgatgga atcgcaatgc ctcacagcaa aaacgctgct gtcaaagaag
    13741 cgacagttct atttgctaag tcaaacaagg gtgttgacta cgagagcttg gatggacaag
    13801 caactgacct cttcttcatg attgcagctc cagaaggtgc caatgatact cacttggcag
    13861 ccttggcaga attgtctcaa tacttgatga aagacggttt tgcagacaaa cttcgtcaag
    13921 caacatctgc agaccaagtt atcgaacttt ttgaccaagc ttcagaaaaa actgaggaac
    13981 ttgttcaagc acctgctaat gactctggtg actttatcgt agctgttaca gcttgtacaa
    14041 caggtattgc ccacacttac atggcccaag aagcccttca aaaagtagct gctgaaatgg
    14101 gggttggtat caaggtcgaa accaacggtg ctagcggtgt tggaaatcaa ctaactgcag
    14161 aagatatccg taaggctaaa gctattatca ttgcagcaga caaggccgtt gaaatggatc
    14221 gatttgatgg aaaaccattg atcaatcgtc cagttgctga cggtatccgt aagacagaag
    14281 agctaattaa cttggctctt tcaggagata ctgaagtcta ccgtgccgct aatggtgcca
    14341 aagctgcaac agcctctaac gaaaaacaaa gccttggtgg tgccttgtac aaacacttga
    14401 tgagtggtgt atctcaaatg ttaccattcg ttatcggtgg tggtatcatg attgcccttg
    14461 ccttcttgat tgacggtgct ttgggtgttc caaatgaaaa ccttggcaat cttggttctt
    14521 accatgagtt agcttctatg ttcatgaaaa ttggtggagc tgcctttggt ttgatgcttc
    14581 cagtctttgc gggttatgtt gcctactcta ttgctgaaaa accgggtttg gtagcaggtt
    14641 tcgtggctgg tgctattgcc aaagaaggtt ttgcctttgg taaaattcct tatgccgcag
    14701 gtggtgaagc aacttcaact cttgcaggtg tctcatctgg tttcctaggt gcccttgttg
    14761 gtggatttat cgcaggtgcc ttggttcttg ccatcaagaa atacgttaaa gttcctcgtt
    14821 cactcgaagg tgctaaatca atccttctat tgccacttct tggaacaatc ttgacaggat
    14881 ttgttatgct agctgtgaat atcccaatgg ctgcaatcaa cactgctatg aatgacttcc
    14941 taggcggtct tggaggaggt tcagctgtcc ttcttggtat cgtccttggt ggaatgatgg
    15001 ctgttgacat gggtggacca gttaataaag cagcttatgt ctttggtaca ggtacgcttg
    15061 cagcaactgt ttcttcaggt ggttctgtag ccatggcagc agttatggct ggaggaatgg
    15121 tgccaccact tgcaatcttt gtcgcaactc ttcttttcaa agataaattt actaaggaag
    15181 aacgtaactc tggtttgaca aacatcatca tgggcttgtc atttatcact gagggagcga
    15241 ttccatttgg tgccgctgac ccagctcgtg cgattccaag cttcatcctt ggttcagcag
    15301 tagcaggtgg actcgttggt cttactggta tcaaactcat ggcgccacac ggaggaatct
    15361 tcgttatcgc ccttacttca aatgctctcc tttacctcgt ttctgtcttg gtaggagcaa
    15421 tcgtaagtgg tgtggtttat ggttacctac gcaaaccaca agcataaaaa atagaaaaat
    15481 gaaaagattg gaccgtttgg tgcagtcttt ttctcttccc gaaatgcctg tgaaatatgg
    15541 tataatagaa gaatggcaaa caagaataca agtacaacaa gacggagacc gtctaaagca
    15601 gaactggaaa gaaaagaagc gattcaacga atgttgattt cgttaggaat tgcgatttta
    15661 ttgattttcg cagccttcaa attaggggct gcaggtataa ccctttataa tttaattcgc
    15721 ttgctagtgg gtagcctagc ttatctggcg atattcggcc tattaatcta tctcttcttt
    15781 ttcaagtgga tacgaaaaca ggaaggactc ttatctggct ttttcaccat atttgctggc
    15841 ttactcttga tttttgaggc ctacttggtt tggaaatatg gtttggacaa gtccgttcta
    15901 aaagggacca tggctcaggt tgtgacagat ctgactggtt ttcgaacgac tagctttgct
    15961 ggagggggct tgatcggggt cgctctttat attccaacag cctttctctt ttcaaatatc
    16021 ggaacttact ttattggttc tatcttgatt ttagtgggtt ctctcctagt cagcccttgg
    16081 tctgtttacg atattgctga atttttcagt agaggctttg ccaaatggtg ggaagggcac
    16141 gagcgtcgaa aagaggaacg ctttgtcaaa caagaagaaa aagctcgcca aaaggctgag
    16201 aaagaggcta gattagaaca agaagagact gaaaaaacct tactcgattt gcctcctgtt
    16261 gatatggaaa cgggtgaaat tctgacagag gaagctgttc aaaatcttcc acctattcca
    16321 gaagaaaagt gggtggaacc agaaatcatc ctgcctcaag ctgaacttaa attccctgaa
    16381 caggaagatg actcagatga cgaagatgtt caggtcgatt tttcagccaa agaagccctt
    16441 gaatacaaac ttccaagctt acaactcttt gcaccagata aaccaaaaga tcaatctaaa
    16501 gagaagaaaa ttgtcagaga aaatatcaaa atcttagaag caacctttgc tagctttggt
    16561 attaaggtaa cagttgaacg ggccgaaatt gggccatcag tgaccaagta tgaagtcaag
    16621 ccggctgttg gtgtaagggt caaccgcatt tccaatctat cagatgacct cgctctagcc
    16681 ttggctgcca aagatgtccg gattgaagca ccaatccctg ggaaatccct aatcggaatt
    16741 gaagtgccca actccgatat tgccactgta tctttccgag aactatggga acaatcgcaa
    16801 acgaaagcag aaaatttctt ggaaattcct ttagggaagg ctgttaatgg aaccgcaaga
    16861 gcttttgacc tttctaaaat gccccacttg ctagttgcag gttcaacggg ttcagggaag
    16921 tcagtagcag ttaacggcat tattgctagc attctcatga aggcgagacc agatcaagtt
    16981 aaatttatga tggtcgatcc caagatggtt gagttatctg tttacaatga tattccccac
    17041 ctcttgattc cagtcgtgac caatccacgt aaagccagca aggctctgca aaaggttgtg
    17101 gatgaaatgg aaaaccgtta tgaactcttt gccaaggtgg gagttcggaa tattgcaggt
    17161 tttaatgcca aggtagaaga gttcaattcc cagtctgagt acaagcaaat tccgctacca
    17221 ttcattgtcg tgattgtgga tgagttggct gacctcatga tggtggccag caaggaagtg
    17281 gaagatgcta tcatccgtct tgggcagaag gcgcgtgctg caggtatcca catgattctt
    17341 gcaactcagc gtccatctgt tgatgtcatc tctggtttga ttaaggccaa tgttccatct
    17401 cgtgtagcat ttgcggtttc atcaggaaca gactcccgta cgattttgga tgaaaatgga
    17461 gcagaaaaac ttcttggtcg aggagacatg ctctttaaac cgattgatga aaatcatcca
    17521 gttcgtctcc aaggctcctt tatctcggat gacgatgttg agcgcattgt gaacttcatc
    17581 aaggctcagg cagatgcaga ctacgatgag agttttgatc caggtgaggt ttctgaaaat
    17641 gaaggagaat tttcggatgg agatgctggt ggtgatccgc tttttgaaga agctaagtct
    17701 ttggttatcg aaacacagaa agccagtgcg tctatgattc agcgtcgttt atcagttgga
    17761 tttaaccgtg cgacccgtct catggaagaa ctggagatag caggtgtcat cggtccagct
    17821 gaaggtacca aacctcgaaa agtgttacaa caataaaaaa atagcttctt tccgagtttg
    17881 gagggaagct attttagtgg ctattgattg cttttatttt ctgaagttgg cgcattggac
    17941 tgtttttcgt tttcagtagc aggtttactt gaagcaggag tagaagagtc ctgagttgct
    18001 gttttctgat cttctttttt ctcttccttg acgctagatt ttggtgtttc ctcttgctgt
    18061 gttttttctt gactagtgtt agtctcttta gttggactgg tgttttcctt aggggattcc
    18121 ttttggattt ctttgacaat ggttgtcgtc tggcttgtcg taggttcttt tttaatattt
    18181 ttgttattat ccaaggcgtt catgatcgtg atacccgcgg taatcaagcc aaggatacta
    18241 gcgattgtag caacggtttt ttgaaagact gtaaagcctt ttttgatgtg ttctgttttt
    18301 ggttttgaag ttctacgata gttagacata cattctctcc tttgattatg atttattata
    18361 ctctgtttct ttaaaaaaat cttaaaaaaa gagaaattgc cctttcttgt cgcaggctcc
    18421 gtttcatgat acaatagaag gagtgatttt agaaagcgtg agaaacatga tttactttga
    18481 taattcggcg acgaccaggc cctatccaga agcccttgaa acctatatgc aggtggcttc
    18541 aaaaatttta ggaaatccat ctagtctcca tcgtttggga gaccaggcaa cacgaatttt
    18601 agatgcttcc cgtcaacaga ttgcagattt aatcggtaag aaaagtgatg aaatcttctt
    18661 tacatctggt gggacagaag gggataactg gatcatcaag ggagtagcat ttgaaaaagc
    18721 ccagtttggc aagcacatca tcgtatcagc cattgaacat ccagcagtta aggaatcagc
    18781 cctctggttg aaagctcaag gttttgaagt ggattttgct ccagttgata acaaaggatt
    18841 tgtggatgtt gaggcgctag aagatttgat aagacctgat acgaccctcg tttccatcat
    18901 ggcagttaac aatgaaattg gctctgttca gcccattgag gctatttcaa aactattggc
    18961 agacaagcca actatttcct tccacgttga tgcggttcag gcgcttgcca agattccgac
    19021 tgaaaagtat ctgacagaac gagtggattt cgcgactttc tctggtcaca agttccacgg
    19081 aatccgtggt gttggtttta tctatatcaa gtctggcaag aagattacgc ctcttttaac
    19141 aggtggtggt caggaacgtg attaccgttc gacaactgaa aatgtggcag gaattgcagc
    19201 gaccgctaag gctctccgtt tatctatgga aaagctagat atctttagga gcaagactgg
    19261 gcagatgaag gcagtgattc gtcaagcact tctggactat ccggatatat ttgtcttttc
    19321 agatgaggaa gacttcgccc ctcatattct gacttttgga atcaagggtg ttcgtggtga
    19381 ggtcattgtt cacgcctttg aagactatga tattttcatc tcaacgacct cggcttgttc
    19441 gtccaaggct gggaaaccag ccggaaccct gattgctatg ggagtggaca aggataaggc
    19501 tcagtcagct gtgcgtctta gtctagacct tgaaaatgat atgagtcagg tcgagcagtt
    19561 cttgaccaag ctaaaattaa tttacaatca aactagaaaa gtaagatagg agcattcatg
    19621 cagtattcag aaattatgat tcgctacggt gagctgtcaa ccaagggcaa aaatcgtatg
    19681 cgtttcatca ataaacttcg caataatatt tcagacgttt tgtctatcta tccccaagtt
    19741 aaggtaacag cagatcgcga ccgtgcccac gcttacctca atggagcaga ttacacagca
    19801 gtagcagaat cgctcaaaca agtatttgga attcaaaact tttcccctgt ttataaggtt
    19861 gaaaaatctg tagaagttct gaagtctgct gtccaagaga ttatgcagga catctacaag
    19921 gaaggcatga cctttaaaat ctctagcaag cgtagcgacc acacctttga attggacagt
    19981 cgtgaactca accaaacgct tggaagggct gtattcgaag ccattccaaa cgtacaagct
    20041 caaatgaaaa gtcctgacat caatcttcag gtggagatac gtgaagaagc agcctatctt
    20101 tcttatgaaa ccgttcgagg ggcaggtgga ttaccagtgg gaacttctgg taagggcatg
    20161 ctcatgttgt cagggggaat cgattcccct gtagctggct atctagcgct taaacgaggg
    20221 gtagatatag aggcagttca ctttgccagc ccaccttaca cgagtcctgg tgctcttaaa
    20281 aaagcccaag atttgacccg taaattaacc aaatttgggg gaaatatcca gtttatcgaa
    20341 gttcctttta cagagattca agaggaaatc aaagccaaag cgccagaagc ctaccttatg
    20401 accttgacgc gtcgttttat gatgcgtatt actgaccgta ttcgtgaggt acgaaatggt
    20461 ttagttatca tcaatgggga aagtctaggt caagtagcca gccaaaccct tgaaagtatg
    20521 aaggctatca atgctgttac caacactccc atcattcgtc ctgtggttac catggacaag
    20581 ttggaaatca ttgacatcgc ccaggaaatc gatacctttg acatttcaat ccaaccgttt
    20641 gaagactgtt gtaccatttt tgcaccagat cgtccaaaaa caaatcctaa aattaagaat
    20701 gcggagcagt acgaagcgcg tatggatgtt gaaggcttgg ttgagcgagc agtggctgga
    20761 atcatgatta ctgaaatcac acctcaagcc gaaaaagatg aagttgatga cttgattgac
    20821 aatctgctct aattcagaaa atccaaaaga atagcgaaaa tcagtaaaaa aa
//
LOCUS       DAVLBN010000037        20607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLBN010000037 DAVLBN010000000
VERSION     DAVLBN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.037"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..197
                     /locus_tag="VXC24_001367"
     CDS             <1..197
                     /locus_tag="VXC24_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493472.1"
                     /translation="RLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSFLKQ
                     LAKLYQVTTDYILEMDKFSC"
     gene            328..480
                     /locus_tag="VXC24_001368"
     CDS             328..480
                     /locus_tag="VXC24_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493473.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            647..2440
                     /locus_tag="VXC24_001369"
     CDS             647..2440
                     /locus_tag="VXC24_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0493474.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            2545..3132
                     /locus_tag="VXC24_001370"
     CDS             2545..3132
                     /locus_tag="VXC24_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0493475.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYINQEFKSYIDHM
                     LNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            3414..3662
                     /locus_tag="VXC24_001371"
     CDS             3414..3662
                     /locus_tag="VXC24_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV0493476.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            3838..4091
                     /locus_tag="VXC24_001372"
                     /pseudo
     CDS             3838..4091
                     /locus_tag="VXC24_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4219..5448
                     /locus_tag="VXC24_001373"
     CDS             4219..5448
                     /locus_tag="VXC24_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0493477.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5468..8164
                     /gene="ppc"
                     /locus_tag="VXC24_001374"
     CDS             5468..8164
                     /gene="ppc"
                     /locus_tag="VXC24_001374"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0493478.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8247..8464
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8577..9581
                     /locus_tag="VXC24_001375"
     CDS             8577..9581
                     /locus_tag="VXC24_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0493479.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            9650..10516
                     /locus_tag="VXC24_001376"
     CDS             9650..10516
                     /locus_tag="VXC24_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493480.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10513..11271
                     /locus_tag="VXC24_001377"
     CDS             10513..11271
                     /locus_tag="VXC24_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493481.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            11361..13121
                     /gene="dnaG"
                     /locus_tag="VXC24_001378"
     CDS             11361..13121
                     /gene="dnaG"
                     /locus_tag="VXC24_001378"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0493482.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13124..14233
                     /gene="rpoD"
                     /locus_tag="VXC24_001379"
     CDS             13124..14233
                     /gene="rpoD"
                     /locus_tag="VXC24_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0493483.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14247..14576
                     /locus_tag="VXC24_001380"
     CDS             14247..14576
                     /locus_tag="VXC24_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0493484.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14691..15734
                     /gene="cpoA"
                     /locus_tag="VXC24_001381"
     CDS             14691..15734
                     /gene="cpoA"
                     /locus_tag="VXC24_001381"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0493485.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            15750..17075
                     /locus_tag="VXC24_001382"
     CDS             15750..17075
                     /locus_tag="VXC24_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0493486.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17106..17282
                     /locus_tag="VXC24_001383"
     CDS             17106..17282
                     /locus_tag="VXC24_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0493487.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            17341..17475
                     /locus_tag="VXC24_001384"
     CDS             17341..17475
                     /locus_tag="VXC24_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0493488.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17539..18849
                     /gene="obgE"
                     /locus_tag="VXC24_001385"
     CDS             17539..18849
                     /gene="obgE"
                     /locus_tag="VXC24_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0493489.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18859..19017
                     /locus_tag="VXC24_001386"
     CDS             18859..19017
                     /locus_tag="VXC24_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493490.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(19069..20395)
                     /locus_tag="VXC24_001387"
                     /pseudo
     CDS             complement(19069..20395)
                     /locus_tag="VXC24_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6559 a         3413 c         4541 g         6094 t
ORIGIN      
        1 tcagattaaa gaatttaaga gaagacaaag atttgtccca gtgtcaaatt gcacagtatc
       61 ttcattgttc acagtctgct tattctagaa tagaaagtgg caagcaagat attcctacat
      121 catttttgaa acaattagct aaattatatc aggtaactac agattatatt ttagagatgg
      181 ataagtttag ttgttaataa atcctaagcc ctttgaaaac tgaataaacc gaggtgggac
      241 tttcttattt gtcgagcact ttagcttgat acgccgtgat aggagcgata attattagct
      301 ataaaataga gtggttctct atctgccatg actacaaata aggataatga tacttctgaa
      361 cgttcaggct gccagcgaaa aaggacagcg ggtgaaatgc ccatgaatga tttaaccagt
      421 catacccacg gaggaaatta tacatgttac aaggaggaaa aagtttggaa caatcagtaa
      481 taaagtatac tatgcaacta tcaatgctta actttttata ctcaagaaat atgttatcta
      541 aaaatgagta tgacaagatt agaaacaaac tgcgtattaa gtacacaaaa tagctgactt
      601 tttgatttga atgcggtaat atagaatcaa aaggaggaat ttcagtatga aaaaaaataa
      661 tgttgaaata ataaaagctg attctttagt tcgtcgaaga ggcgacaatg tagaaagaca
      721 cttaaagagg gttgctgctt attgcagagt tagttccgat agtgaggatc agaaaaacag
      781 ttatgattct caagtaagac actacaaaga atatatttct cagcgttcag attgggagct
      841 ggcagatatt tatgcagatg aaggtatttc aggaacacaa gtaggaaaga gacaagattt
      901 tcaacgatta atcaatgatt gtgcaaatgg agagatagat tatattgtca caaaagcaat
      961 tgctagattt gcaaggaata ccctagatac tttgaagtat gtcagaatgt taaaggatat
     1021 gcaaattgga gtatattttg aggaagaaaa catagatacc ctaacaatgg atggagaatt
     1081 gcttctaact attctaagct ccgttgcaca gcaagaagta gagaatactt ctgcccatgt
     1141 gaaaaaagga ttaaaaatga agatgcaacg tggtgaattg gttggttttc aagggtgctt
     1201 agggtatgat tatgatgtag aaaccaagca gatttcaatt aataaaaaag aagccaaaat
     1261 tgttcgttat atttttgaaa ggtatctaga aggtattgga ggaaaagtaa ttgcaaggga
     1321 acttgatgaa cttggttaca aatcgccaag aggtttagaa cactggaatg atacaacagt
     1381 tctaggaata ataaagaatg aaaaatataa aggtgatatt ctaatgggaa aaacttttac
     1441 agttgaccca ataagcaaga gacggttgag taattttgga gaagaagata agtactatat
     1501 caaggataat catgaaccaa taatatctaa agaagatttt gaaaaagctc aggagattag
     1561 attgcgtcga gcaggaaata agaagacagc tgcgaatgta aatgggaagc gtgaacgcta
     1621 ttcaaaaatg tatgctttta gtagcatgtt ggaatgtggt ttttgtggtt caatattatc
     1681 tagaagaagt tggcactgcc gttcagatta tcgcaaagtt gtgtggcact gtgttacatc
     1741 gataaagaaa ggaaagaaat tttgtaagca tagtaaagga ttagaagaga tcgccattga
     1801 gggggctttc ctggaagctt acagacaagt ctatcattca aatgaaaatt taatgacaga
     1861 cttacttgaa acgatagaat ctgaattgaa tgacaatagc cttaacaagg aactaaaaag
     1921 gattacaaac aaacttcgaa tattactaaa aaaagaggag aatcttgtaa atctaaggct
     1981 cgaaggaaaa gttagcgatt ccatatacaa tgaaaagtac aatgaaattt cctcagaaaa
     2041 agagtttcta gcagaagaga aggtaaatat tgaaacaaca ttaaaatcag aaatcgatgt
     2101 aaagaaaaga ctaactgagt ttaagcactt gctatcttcg caaaaaatgc ttacggagtt
     2161 tgatcgtgca gtttttgaaa gtattgttga gaaaattatt gtaggtggag ttaatagcaa
     2221 cggagaaatt gatcctgcaa tgttaaccat aatattcaaa acaggtgaaa ttcaaaacaa
     2281 ggatggtaaa caatttaaaa gtaaacgtaa aaatgctaaa ctagaaacag ataaattgtg
     2341 tcctcaaaac agtgacgagg ataaaaaatt gtattctcaa ggaacagaca acacacgtgg
     2401 agtgtgtagt gttgctggtt cgatcttagc cagtcaataa aatgatatgt tttaaaaaaa
     2461 ttataatttc gaaacgtgaa taaacttgtt taaactttat gtatctttag aaagtgtgtt
     2521 aacttgaaag aacaaatttt tttgatgggt gggaatcccc caataaagaa atatagtatt
     2581 gttgataaaa ttgtattatc aaccaagatt aaaagaatta tcatttttac agtttttcga
     2641 gaaaattggg aaccgtacat gaaaaagtac acggaagttt ttcaaagtca atttcctaat
     2701 ctaaacattg attacttgct cctggacact gagcagattg atcttgatag ctatctagat
     2761 gctgacataa ttatcatcgg tggtggaaat acggaaaaat atattgctac ttatattaat
     2821 caggagttca aaagttatat cgatcatatg cttaataaag aggcaaaaat tataggattt
     2881 tctgcaggac ccctactatt aggagaaaaa gtctatgtct cacctaatga taattcagat
     2941 catcagataa agataaaaaa tggattagga ctctttagtc agtttttaat tagtgtccat
     3001 tatgattcct ggaatgataa agcaaataag gatagagctg aagaactcga taatgttccc
     3061 ataattccac taaatgatca ttcttgtctt gtattggata aacttggaaa catcatagag
     3121 aaaattgact aactttcata atgtaaaaat ggatctagga aataaaagtg tagacgaact
     3181 ggataggtta ctagtgaaaa ctgcaaaaag tgttgtaaag tgaatcggag tgtgcttgat
     3241 ggattttagt agtaagatag ccataaataa aggctggtca gatgataaaa aatattgtgt
     3301 gacagatcaa aatcagtaaa aatatttctt gcgtgtttct gataagtcga agttagatta
     3361 taaaaaaatt tgaatttgat atgatggaga aagtagcttc tcttggagtt ccgatgtgta
     3421 aaccaattag cattgaactc tgcgatgacg aagtacattc tttacacgaa tggatagacg
     3481 gaagagatgc aatagatagc attttaactt attcagaaaa ccaacaatac acatatggtg
     3541 tagaagcagg aaagatactt agaaagattc atacaattcc tgctacagaa gtttgtgaag
     3601 attgggaaat cttttttaat ctaaaaattg atgataaaat ctccaacgaa atgatatggt
     3661 aagtccgaaa cgctcagtgt gtaagcttgt tgctaaaagc gtaaaaacct tggaacgaaa
     3721 ggaataatag acttcctgcg aaacaaaaat acaatacaat aaaactatgg atgatgaagc
     3781 aagtaaacaa ttaagcgata gccgtttcaa gagccttgta ggtgttcagc gcacgagatg
     3841 ttagctgtgt taaaaacagc ttatcaacgc aacgtaaacg cgcaaaaggt ggacgaaaaa
     3901 ccaaattaag cctagacgat ctcctcatgg taactattca atacatgcga gaatagcgca
     3961 cttatgaaca aattgcggct gattttggca ttcacgaaag caacttaatc cgtcggagcc
     4021 aatgggttga agtaactctt gttcaaaatg gttttacgat ttcaaattct gccctaatta
     4081 tgaaaaacag taaaattcga aggattgtaa ggtaagagtt tttttctttc tgaaaaaatg
     4141 gtataatagc aatcaaaact agaaaataaa acggaatttg gaacagattt gtctgtatcc
     4201 tagtagagtg gtgatgctat gaagattagt aagaggcact tattaaatta ttccatcttg
     4261 attccctact tgcttttatc tattttgggc ttgattgtgg tctattcgac caccagtgct
     4321 attttaattg aagaaggcaa gagcgccttg cagttggttc gaaaccaagg aatcttttgg
     4381 attgttagtt tgatactgat tgccttaatt tataaattga gactagattt tttgagaaat
     4441 gagcgactaa tcattttagt tatattaata gaaatgcttt tattgttctt ggctcgtttt
     4501 attggtattt ccgtaaacgg ggcatacggt tggatttcgg ttgcaggaat aactattcag
     4561 ccagctgagt acttaaaaat cattattatt tggtatttag ctcaccgatt ctccaaacag
     4621 caagaagaaa tagctactta tgattttcaa gttttgactc aaaatcaatg gcttccccgt
     4681 gcttttaatg attggcgatt cgttctccta gttctgattg gaagtttggg aattttccct
     4741 gatttaggaa atgcgactat tttagtcttg gtttccttga tgatgtatac agttagtgga
     4801 atcgcttatc gctggttttc aaccattctg gcgctcgtat ctgccgcttc tgtctttgtc
     4861 ttgaccacta tcagcctaat cggtgttgag accttttcaa aaattccagt atttggctat
     4921 gtagccaagc gctttagtgc cttttttaat ccttttgccg atcgtgctga tgcaggtcac
     4981 cagttagcta attcttattt tgccatggtc aatggcggtt ggtttggtct aggtcttgga
     5041 aactcgattg aaaaacgagg ttatttgcca gaagctcata cagactttgt cttttctatc
     5101 gtgattgaag aatttggctt tgttggtgcc agtcttattt tagctctctt gtttttcatg
     5161 attttgcgga ttatcttggt cggtatccga gcggagaatc ctttcaatgc catggttgca
     5221 ctcggtgtcg gagggatgat gttggttcag gtatttgtca atatcggagg gatttcgggc
     5281 ttgattccat ctacaggagt gactttcccc ttcttatccc agggtggaaa tagtcttcta
     5341 gtcttatcag tggcagtagc ctttgtctta aatattgatg ccagtgaaaa acgcgctaaa
     5401 ttgtaccgag aattggaaaa tcaaccaatg aaccttctgt tgaagtagga taaagaaagg
     5461 atagtttatg tctcttcaaa aattagaaaa ttatagtaat aaaagtgttg tgcaagaaga
     5521 agtcttgatt ctaacagaat tactggaaga tattactaaa aatatgcttg ccccagagac
     5581 ctttgaaaaa ataatacagt tgaaagaatt atcaacgcag gaagattatc aaggtctaaa
     5641 ccgtctagtg actagcttat caaatgatga aatggtctat atttcacgct atttctctat
     5701 cttgcctctt ttgattaata tttcagagga tgtggattta gcttatgaaa tcaatcatca
     5761 aaataatatt gatcaggact atttaggtaa attatctaca acgattaaat tggtagcaga
     5821 aaaggaaaat gccgttgaga tcctagaaca cttgaatgtt gtccctgttt tgacagccca
     5881 tccaacacaa gtgcaacgca aaagtatgtt ggatttaaca aatcatattc atagtctttt
     5941 gcgtaaatac cgtgatgtta agttggggtt gatcaataaa gataaatggt acaatgattt
     6001 gcgtcgttac atcgaaatta tcatgcagac agacatgatt cgtgagaaaa aattaaaagt
     6061 gactaacgaa atcacgaatg ctatggaata ttataacagc tcctttttga aagctgtacc
     6121 tcatttgacg acggagtata agcgcttagc gcaagcgcat ggtctgaatt taaaacaggc
     6181 taaaccaatc accatgggta tgtggatagg tggtgaccgt gatggaaatc catttgttac
     6241 agcaaagacc ttgaagcagt ctgcactcac tcagtgtgaa gtcatcatga actactatga
     6301 taaaaagatt taccaacttt atcgtgaatt ttctctttca actagcattg tcaacgtcag
     6361 caagcaagtc agagaaatgg ctcgtcaatc caaggataac tcgatttacc gcgaaaaaga
     6421 gctttaccgt cgtgccttgt ttgatattca atcaaaaatt caggcaacta aaacctatct
     6481 gattgaggat gaagaagttg ggactcgtta tgaaaccgcc aatgatttct acaaggattt
     6541 gattgccatt cgagattctc tactagaaaa taagggcgag tccttgattt caggtgattt
     6601 tgtggaatta ttgcaggcag tagagatatt tggtttttac ttagcatcaa ttgatatgcg
     6661 acaagactct agcgtctatg aagcctgtgt ggcagaactc ttgaaatcag caggaattca
     6721 ttctcgttat agcgagttga gcgaagaaga aaagtgtgac cttctcttga aagaattaga
     6781 agaagatccc cgaattcttt ctgcgactca cgcagaaaaa tcagaattat tagcaaaaga
     6841 actagctatt tttaagacgg ctcgtgtttt gaaagataag ttgggagatg atgtcatccg
     6901 tcagaccatc atttcacatg caaccagcct ttctgatatg ctagaattag ctattctgtt
     6961 aaaagaagta ggactggtgg atacggaaag ggcgcgtgtt cagattgttc ccctttttga
     7021 aacaattgaa gacttggatc attcagagga aacaatgaga aaatatcttt ctcttagcct
     7081 tgccaaaaaa tggattgact cacgaaataa ctatcaagaa atcatgcttg gctactctga
     7141 cagtaataaa gatggcggtt acttgtcatc atgttggacc ctctacaagg ctcaacaaca
     7201 attgactgct attggagatg aatttggcgt taaggttacc ttcttccatg gtcgtggtgg
     7261 tactgtcggt cgtggtggtg ggccaaccta tgaagccatt acatctcaac cgctcaagtc
     7321 tatcaaggat cgtatccgct tgacggagca gggtgaagta attgggaata aatacggtaa
     7381 caaagacgcc gcttactata accttgaaat gctagtatcg gcagctatta accgtatgat
     7441 tactcagaag aagagcgata ccaatacccc aaatcgttat gaagccatta tggatcaagt
     7501 agtggaccgt agttacgata tctaccgtga tttggtcttt ggtaatgagc atttctatga
     7561 ttatttcttc gagtcaagtc caatcaaggc tatttcaagt tttaatattg gttctcgtcc
     7621 agccgctcgt aagactatta ctgaaatcgg tggattgcgt gctatccctt gggtattctc
     7681 atggtcacag agtcgtgtta tgttccctgg atggtacggg gttggttcaa gcttcaagga
     7741 atttatcaat aaaaatccag agaatattgc tatcttacga gatatgtacc aaaattggcc
     7801 tttcttccaa tcgcttcttt caaatgttga tatggttttg tcaaaatcaa atatgaatat
     7861 tgcttttgaa tatgctaaac tttgtgaaga cgagcaagtt aaggccatct atgagactat
     7921 tttaaatgaa tggcaagtta ctaagaacgt tatcttggct attgaaggac atgacgaact
     7981 cttagctgac aatccatatc taaaagctag tctggattac cgtatgcctt actttaatat
     8041 tctcaactat attcagttag agttgattaa acgccaacgt cgtggagaat tgtccagtga
     8101 tcaagaacga ttgattcata tcaccatcaa cggaattgcg acaggattgc gtaattcagg
     8161 ttgataattt tcaagagtga atgctaaaag tgaatatcaa aaaaattcta atagactatt
     8221 gacaagtagt ttaaaaatga tataatttaa ccattcagaa aagtaatcat acaaactttt
     8281 tagagagtct gtggtagctg aaaacagata agtggcaatg atgaaaattg ggctgaatgc
     8341 tatttagaat ttgaaattat aaaaattcgg taagcacacc ttacagtgca tctcgttatt
     8401 gcgagactga gcgataggga aattccctat aattgaggtg gtaccgcgca tcgacgtcct
     8461 cacacaagtt ttttgtgtga ggattttttt gatggaggtt agtatagaaa gaaaacgatg
     8521 gcgtcgcttg tttagataag tgaaatatgt taaaggaaat aaaaaggaga aacagaatga
     8581 aaaataaacg tttaattgga attattgctg cattagcagt cttagtagca ggaagcttga
     8641 tttattcttc aatgaataaa tcagaagctc agaataataa ggatgagaag aaaataacca
     8701 agattggtgt gcttcaattt gtgagccatc catcccttga tttgatttat aaagggatcc
     8761 aagatggact tgcagaagaa ggatataaag atgatcaagt taaaattgat tttatgaact
     8821 cagaaggtga ccaaagtaag gttgcgacaa tgagtaaaca attggttgca aatgggaatg
     8881 accttgtggt tggtatcgca acaccagcag cccaagggtt ggctagtgca acaaaagacc
     8941 taccggttat catggccgct attacagacc caattggtgc taacttggtt aaagatttga
     9001 aaaaaccagg tggcaacatt acaggggtat ctgaccacaa tccagctcaa caacaagttg
     9061 aactcatcaa ggctctgaca ccgaatgtga aaacaatcgg agctctttac tcaagtagcg
     9121 aagacaattc aaaaacacag gtcgaagaat ttaaggctta tgctgaaaaa gcaggtctga
     9181 cagtggaaac atttgcagtt ccttcaacaa atgaaattgc ctcaactgtc actgttatga
     9241 ctagcaaggt agatgctatt tgggttccaa ttgataacac cattgcatca ggatttccaa
     9301 cggttgtctc tagcaatcaa agttctaaga aaccaattta tcccagtgcg acagctatgg
     9361 tagaagtagg tggtttggca tcagttgtaa ttgaccaaca tgaccttggt gtggcaacag
     9421 gtaaaatgat tgtgcaagtc ttgaaaggtg caaaaccagc cgatacccca gtcaatgtct
     9481 tttcaactgg taagtcagtc atcaataaaa aaatagcaca agaactaggt attactattc
     9541 ctgagtttgt tctcaaagaa gcaggacaag tcatcgaata aataaggtag ggaggaggag
     9601 actcttccca ttttttaaaa agatgaatat agaaaggatt aaataaaata tgattgtttc
     9661 cattatttct caaggatttg tctgggctat tctaggtctg ggaatcttta tgacatttag
     9721 gattttaaac tttccagata tgacgacaga aggttccttc cctcttgggg gagctgttgc
     9781 tgtcactttg ataaccaaag gcgtgaaccc atttttagcg acacttgttg ctgtaggagc
     9841 aggttgtttg gctggaatgg cagcaggcct tctttataca aaagggaaga tcccaacctt
     9901 gctctcaggg attttggtga tgacttcttg tcactcaatc atgctcttga ttatgggacg
     9961 tgcaaattta ggcctgcttg gaaccaagca aattcaggat gttttgcctt ttgattcgga
    10021 tttgaatcaa ctcttgacag gtctcatctt tgtgagtatt gttattgctc tcatgctctt
    10081 tttcttggac actaaactcg gacaagccta tattgctaca ggggataatc ctgatatggc
    10141 tagaagtttc gggattcata ctggacacat ggagctcatg ggcttggtct tatcaaatgg
    10201 tgtgattgcc cttgcaggtg ccctcattgc tcagcaagaa ggttatgccg atgtgtctcg
    10261 agggatcggg gttatcgttg tggggcttgc aagtttgatt attggagaag ttattttcaa
    10321 gagtttgagc ttggcagagc gtttggttac tatcgttgta ggttctatcg cttatcaatt
    10381 tttagtgtgg gcagttatcg cacttggctt taatacaagt taccttcgtt tatacagtgc
    10441 cttgatttta gcagtctgcc tcatgattcc aacatttaag caaacaatct tgaaaggagc
    10501 caagttaagc aaatgacagc aattgtagaa ttaaaaaatg caaccaaaat cgttaaaaat
    10561 ggctttgatg aagaaaagat tattttaaat gatgtttcct tagaaatttt tgaacaggac
    10621 tttatcacga ttttgggtgg aaatggtgct ggtaaatcaa ccctctttaa cactattgca
    10681 ggaaccatat cactaaccag tggaactatc cgtattttag gtgaggatgt taccaagttt
    10741 tcaccagaga agcgcgctaa gtatctgtct cgagtcttcc aagatccaaa gatggggaca
    10801 gctcctcgta tgacagtggc agagaatctc ctgattgcca agtttcgtgg tgaaaagcgt
    10861 ggactatttc cgagacgtct ggctagctat aaggataagt ttcaggcgac cattgaaaaa
    10921 gtgggaaacg gtcttgagaa acacttgaat acaccgattg agttcttatc tggtggacaa
    10981 agacaggctt tgagtctctt gatggcaacc ttgaagcgac ctgaattact cttgttagac
    11041 gagcatactg ctgccctgga tccaaagact agtgttgctt tgatggaatt gacagatgaa
    11101 tttgttaaga aagatcaatt gacagccctt atgattaccc atcatatgga agatgctctc
    11161 aaatatggca atcgcttgat tgtcatgaaa gaaggacggg ttatccaaga tttgaaacaa
    11221 gaagaaaaag caaaaatgaa aatctctgat tattatcaac tctttgaata aagtagggaa
    11281 aatgagtgaa atggtttact ttttttctga aataaagtat actatataaa gtaaactatg
    11341 ataacatgga ggtattgtgt atggttgaca aacaagtcat tgaagaaatc aaaaacaatg
    11401 ccaacattgt ggaagtcata ggagatgtga tttctttaca aaaggcagga cggaactatc
    11461 tagggctctg tccttttcat ggtgaaaaaa caccttcttt caacgttgta gaggacaagc
    11521 agttttacca ctgttttggt tgtggtcgct caggtgatgt ctttaaattc atcgaggagt
    11581 accaaggggt tacctttatg gaggctgtcc aaatcttagg tcagcgtgtc gggattgagg
    11641 ttgaaaaacc gctttatagt gaacagaagc cagcctcgcc ttaccaagct ctttatgata
    11701 tgcacgaaga tgcggctaaa ttttaccatg ctattctcat gacaacgact atgggcgaag
    11761 aggccagaaa ttacctttat cagcggggtt tgacagatga agtgcttaaa catttttgga
    11821 ttggtttagc acctccagaa cgaaactatc tctatcaacg tttgtctgat cagtatcgtg
    11881 aagaggattt actggattca ggcctgtttt atctctcgga tgccaatcaa tttgtagaca
    11941 cctttcacaa tcgcattatg tttcccctga caaatgacca aggaaaggtc attgccttct
    12001 caggtcgtat ctggcaaaaa acggattcac aaacttctaa gtataaaaac agccgatcga
    12061 ctgcaatttt taacaaaagt tacgaattat atcatatgga tagggcaaaa aaatcttctg
    12121 gaaaagctag tgagatttac ctgatggaag gattcatgga tgttattgca gcctatcggg
    12181 ttggaatcga aaatgctgtg gcgtcgatgg gaacggcctt gagtcgagag catgttgagc
    12241 atctgaaaag gttaaccaag aaattggttc ttgtttacga tggagataag gctgggcaag
    12301 ccgcgatatt gaaagcattg gatgaaattg gtgatatgcc tgtgcaaatc gtcagcatgc
    12361 ctgataactt ggatcctgat gagtatctac aaaaaaatgg tccagaagac ttggcctatc
    12421 tattaacgaa aactcgtatt agtccgattg agttctacat tcatcagtac aaacctgaaa
    12481 acagtgaaaa tctgcaggct cagattgagt ttattgaaaa aatagctccc ttgattgtta
    12541 aagaaaagtc catcgctgct caaaacagct atattcatat tttagctgac agtctggcgt
    12601 cctttgatta tgcccagatt gagcagattg ttaatgagag tcgtcaggtg caaaggcaga
    12661 atcgcatgga aagaatttcc agaccgacgc caatcaccat gcctgtcacc aagcagttat
    12721 cggctattat gagggcagaa gcccatctac tctatcggat gatggaatcc cctcttgttt
    12781 tgaacgatta ccgtttgcga gaagactttg catttgctac acctgaattt caggtcttat
    12841 atgacttgct tggccagtat ggaaatcttc ctccagaagt tttagcagag cagacagagg
    12901 aagttgaaag agcttggtac caagttttag ctcaggattt gcctgctgag atatcgccgc
    12961 aggaacttag tgaagtagag atgactcgaa acaaggctct cttgaatcag gacaatatga
    13021 gaatcaaaaa gaaggtgcag gaagctagcc atgtaggaga tacagataca gccctagaag
    13081 aattggaacg tttaatttcc caaaagagaa gaatggagta ataatggcaa caaaacaaaa
    13141 agaagtaaca acatttgacg tacaggtagc agaatttatc cgtaatcata agcaaaaagg
    13201 gacagcaaca gatgatgaaa tcaatgcaag tctggttatt ccttttacct tggacgctga
    13261 tgggattgaa gatctcttgc aacggattca ggatgcaggc atttctatca cagataacga
    13321 aggaaatcca agtgcgcgtg ttcttagcaa tgaagaagaa ccagaactca gcgatgagga
    13381 cttgattggg tcaacttctg ctaaggtcaa tgaccctgtc cgtatgtact tgaaagaaat
    13441 aggggtcgtt cctctcttga ccaatgaaga ggagaaagag ttggcactgg ctgttgaagc
    13501 tggcgatatc gaagccaaac aacgtcttgc ggaagccaat cttcgtttgg ttgtttccat
    13561 tgccaaacgc tatgtcggtc gtggcatgca gttccttgac ttgattcaag aaggaaatat
    13621 gggcttgatg aaggcggttg acaagtttga ctattctaaa gggttcaagt tttcaactta
    13681 tgcaacttgg tggattcgtc aggctatcac tcgtgctatt gcggaccaag ctcgtaccat
    13741 ccgtatccca gttcacatgg ttgaaactat caataaattg gttcgtgaac agcggaatct
    13801 ccttcaagaa ttggggcaag atccgacacc agaacagatt gctgaacgaa tggatatgac
    13861 acctgataag gttcgtgaaa tcttgaagat tgcccaagaa ccagtatctc ttgaaactcc
    13921 tatcggtgaa gaggacgata gccaccttgg agactttatc gaagatgaag tgattgaaaa
    13981 tccagtggat tatacgactc gtatcgtctt gcgtgagcaa ttggatgaaa tcttagatac
    14041 tcttacagac cgtgaagaaa atgttctgcg tctacgtttt ggactagatg atggaaaaat
    14101 gcgcacactt gaagatgtgg ggaaagtctt taacgtaact cgtgagcgta tccgtcagat
    14161 tgaagcaaag gctttgagaa aactacgcca accaagtcgc agcaaaccgc ttcgtgattt
    14221 tattgaagac taagagtgag gaaaatatgg cttatacaga agagcaaatt gaaaacatca
    14281 aaacacggat tttaacagcc ttggaagaag tcatcgaccc tgagttggga atcgatattg
    14341 tcaatcttgg tttgatctat gagattcgtt ttgacggtga cacagggcaa acagagattg
    14401 acatgacttt gacaactatg ggttgtccct tagcagacct tttgacagac cagatttatg
    14461 atgctatgat agaggttcca gaagtaacgg atactgaggt taaattagtc tggtatccag
    14521 cctggacagt tgaaaaaatg agtcgctatg cccgcattgc cctaggcatt aagtaaacat
    14581 ataaaagcat gtgagagact gttggaaaag cgaggaaatt tcccctcttt tcctctagtc
    14641 tctcctttct tttgctgatt ttattcaaag aaaatgatat aatagtagtt atggagaaaa
    14701 agaaattacg catcaatatg ttgagttcaa gtgagaaagt agcaggacag ggagtttcag
    14761 gtgcttaccg tgaattagtt cgtcttcttc accgtgctgc caaggaccaa ttgattgtta
    14821 cagaaaatct tccgatcgag gcagatgtga ctcactttca tacgattgat tttccctatt
    14881 atttatcaac cttccaaaag aaacgctcag ggagaaagat tggctatgtg catttcttgc
    14941 cagctacact tgagggaagt ttgaaaattc catttttctt aaagggaatt gtgaaacgct
    15001 atgtattttc tttttacaac cggatggagc acttggttgt ggtcaatcct atgtttattg
    15061 aggatttggt agcagctggt attccacgtg aaaaagtgac ctatattcct aactttgtca
    15121 acaaggaaaa atggcatcct ctaccacaag aagaggtagt cagactgcgc acagatcttg
    15181 gtcttagtga caatcagttt atcgtagtag gtgctgggca agttcagaaa cgtaaaggga
    15241 ttgatgactt tatccgtctg gctgaggaat tgcctcagat tacctttatc tgggctggtg
    15301 gcttctcttt tggtggtatg acagatggtt atgaacacta taagaaaatt atggaaaatc
    15361 cccctaaaaa tttgattttt ccaggcattg tatcgccaga gcggatgcgc gaattgtatg
    15421 ctctagcgga tcttttcttg ttgcctagtt acaatgagct ctttcctatg actattttag
    15481 aagctgcgag ttgtgaggct cctattatgt tgcgtgattt agatctctat aaggtgattt
    15541 tggagggaaa ttatcgggcg acagcgggta gagaagagat gaaagaggct attttggaat
    15601 atcaagcaaa tcctgctgcc ttaaaagatc tcaaagaaaa ggctaagaat atttccagag
    15661 agtattctga agagcatctg ttacaaatct ggttggactt ttatgagaaa caagccgctt
    15721 tagggagaaa gtaaaaagtg aggtaatcta tgcgaattgg tttatttaca gatacctatt
    15781 ttcctcaggt ttctggtgtt gcgaccagta ttcgaacctt gaaaacagaa cttgaaaagc
    15841 agggacatgc tgtttttatc tttacgacga cagataagga tgtcaatcgc tacgaagatt
    15901 ggcaaattat ccgcattcca agtgttcctt tctttgcttt taaggatcgt cgctttgcct
    15961 accgaggttt tagcaaggca cttgaaattg ctaaacagta tcagctagat attatccata
    16021 ctcagacaga attttctctt ggcctgttgg ggatttggat tgcgcgtgaa ttgaaaattc
    16081 cagtcatcca tacctatcac acccagtatg aagactatgt ccattatatt gctaagggga
    16141 tgttgatccg accgagtatg gtcaagtatc tggttagagg tttcctgcat gatgtggatg
    16201 gggttatttg ccctagtgag attgtccgtg acttgctatc tgattataag gtcaaggttg
    16261 aaaaacgggt cattcctact gggattgaat tagccaagtt tgagcgtccg gaaatcaagc
    16321 aggaaaattt gaaagaactg cgtagtaaac tagggattca agatggtgaa aagacgttgc
    16381 ttagtctttc gagaatctcc tatgaaaaaa atattcaagc agttttagta gcctttgctg
    16441 atgttctgaa agaggaagac aaggttaaac tggtagtagc tggggatggc ccttatctga
    16501 atgacctcaa agagcaagcc cagaacctag agattcaaga ctcagtcatc tttacaggga
    16561 tgattgctcc tagtgagacg gctctttact ataaagcggc ggattttttc atttcggcat
    16621 cgacaagcga aacgcaaggt ttgacctact tggaaagctt agccagtgga acacctgtca
    16681 ttgctcacgg aaatccttat ttgaacaacc tcatcagtga taaaatgttt ggaaccttgt
    16741 actatggaga acatgatttg gctggtgcta ttttggaagc cctgattgca acaccagaca
    16801 tgaacgagca taccttatca gagaaattgt atgagatttc agctgagaac tttgggaaac
    16861 gagtgcatga gttttatctg gatgccatta tttcaaataa cttccagaaa gatttggcta
    16921 aagatgatac ggtcagtcag cgtatcttta agacagtttt gtatcttcag caacaggtgg
    16981 ttgctgtacc tgtaaaagga tctagacgca tgttgaaggc ttcaaaaaca cagttgatca
    17041 gtatgagaga ctattggaaa gaccatgaag aatagaaaga ggaacagcta tgaaaaaaac
    17101 aattaatgag aagcggtcgt gataaaaaga ttgcgggtgt ttgtgctggg gtggcccatt
    17161 atctggatat ggatccgact atcgttcaag tcatttgggg tgttcttact tgctgttacg
    17221 gagctggaat tgtagcttac attattttat ggattatcgt accagtagca actgactatt
    17281 gaaaactagc tcaattcatg ctaagataat agaaaataga atgtaacgaa ggagagaaaa
    17341 atggcatttg gagataatgg aaatcgtaaa aaaactatgt ttgagaaaat aaccttgttt
    17401 atcgtgatta tcatgctagt agcaagttta ttgggaattt ttgcaactgc aattggtgcc
    17461 ctcagtaatc tataaaatag attcaagaaa atttagtgac tgggatttcc cagccctttt
    17521 ttaaagtgag aagaaataat gagtatgttt ttagatacag ctaagattaa ggtcaaggct
    17581 ggtaatggtg gcgatggtat ggttgccttt cgtcgtgaaa aatatgtccc taatggaggc
    17641 ccttggggtg gtgatggtgg tcgtggaggc aatgtggtct tcgttgtaga cgaaggatta
    17701 cgtaccttga tggatttccg ctacaatcgt catttcaagg ctgattctgg tgaaaaaggg
    17761 atgaccaaag ggatgcatgg tcgtggtgct gaggacctta gagttcgagt accacaaggt
    17821 acgactgttc gtgatgcgga gactggcaag gttttaacag atttgattga acatgggcaa
    17881 gaatttatcg ttgcccacgg tggtcgtggt ggacgtggaa atattcgttt cgcgacacca
    17941 aaaaatcctg caccggaaat ctctgaaaat ggagaaccag gtcaggaacg tgagttacaa
    18001 ttggaactaa aaatcttggc agatgtcggt ttagtaggat tcccatctgt agggaagtca
    18061 acacttttaa gtgttattac ctcagctaag cctaaaattg gtgcctacca ctttaccact
    18121 attgtaccaa atttaggtat ggttcgcacc caatcaggtg aatcctttgc agtagccgac
    18181 ttgccaggtt tgattgaagg ggctagtcaa ggtgttggtt tgggaactca gtttctccgt
    18241 cacatcgagc gtacacgtgt tatccttcac atcattgata tgtcagctag cgaaggccgt
    18301 gatccatatg aggattacct agctatcaat aaagagctgg agtcttacaa tcttcgcctc
    18361 atggagcgtc cacagattat tgtagctaat aagatggata tgcctgagag tcaggaaaat
    18421 cttgaagaat ttaagaaaaa attgtctgaa aattatgatg aatttgaaga gttaccagct
    18481 atcttcccaa tttctggatt gaccaagcaa ggtctggcaa cacttttaga tgctacagct
    18541 gaattgttag acaagacacc agaatttttg ctctacgacg agtccgatat ggaagaagaa
    18601 gcttactatg gatttgacga agaagaaaaa gcctttgaaa ttagtcgtga tgacgatgcg
    18661 acatgggtac tttctggtga aaaactcatg aaactcttta atatgaccaa ctttgatcgt
    18721 gatgaatctg tcatgaaatt tgcccgtcag cttcgtggta tgggggttga tgaagccctt
    18781 cgtgcgcgtg gagctaaaga tggggatttg gtccgcattg gtaaatttga gtttgaattt
    18841 gtagactagg agactggtat gggagataaa ccgatatctt tccgagatgc ggatggtaat
    18901 tttgtttccg ccgcagacgt ttggaatgaa aagaaattgg aagaactatt taatcgtctc
    18961 aatccaaatc gtgccttgag attggcacga actaaaaagg aaaatccatc tcagtaaaga
    19021 agctaaaaaa tcccggctct ttgtcaactg tagtgggttg aagaaaagct aagctcgaga
    19081 aaggacaaat tttgtccttt cttttttgat attcagagcg atgaaaatcc gttttttgaa
    19141 gttttcaaag tttcgaaaac caaaggcatt gcgcttgata agtttgatga gattattggt
    19201 cgcttccagt ttggcattag aatagtgtag ttgaagggcg ttgacaatct tttctttatc
    19261 tttgaggaag gttttaaaga cagtctgaaa aataggatga acctgcttaa gattgtcctc
    19321 aataagtccg aaaagtttct ctggttcctt attctggaag tgaaaaagca agagctgata
    19381 gagctgatag tgatgtttca agtcttccga atagctcaaa agcttgttta aaatctcttt
    19441 attggttaaa tgcatacgaa aagtaggacg ataaaaacgt ttatcactca gtttacggct
    19501 atcctgttga atgagtttcc agtagcgctt gatagccttg tattcatggg attttcgatg
    19561 aaactgattc atgatttgga cacgcacacg actcatagca cggctaagat gttgtacaat
    19621 gtgaaagcga tcaagaacga ttttagcatt cgggagtgaa acagtctggg agactgtttc
    19681 agcctgagcc tagaaatttg aaagcgaagc tgtttagcca agccatagta agggctaaac
    19741 atatccatgg taatgatttt gacgcgacat cggacggctc tatcatattt aagaaagtga
    19801 tctcggatga cagcttgtgt tctgccttca agaacagtga tgatattgag attgttaaaa
    19861 tcttgcgcaa taaagctcat ctccatctcc cgattgaaac agtcactccc cggactgttt
    19921 caacgtccca ggacataatc tcaggaagac aagaaaaatc atgtttaaag tgaaaatcat
    19981 tgagcttacg aataacagtt gaagttgaaa tggccagctg atgagcaata tcggtcatag
    20041 aaatcttctc aatcaacttt tgcgcaattt tttggttgat aatacgagga atttggtgat
    20101 ttttcttgac gatagaagtt tcagcgacca tcatttttga acagtgatag cacttgaatc
    20161 gacgctttct aaggagaatt ctagtaggca taccagttgt ctcaaggtaa ggaatcttag
    20221 acggtttttg aaagtcatat ttcttcaatt ggtttccgca ctcagggcaa gatggtgcgt
    20281 cgtagtccag tttggcgatg atttccttgt gtgtatcttt attgatgatg tctaaaatct
    20341 ggatattagg gtctttaatg tctagtaatt ttgtgataaa atgtaattgt cccatatgaa
    20401 tctttctaat gagttgtttt gtcgcttttc attatagatc ttatgggatt ttgtggtacg
    20461 acaggcatgt atagcaaact gaatctggaa tagcacagca tatcttctaa aatattgtta
    20521 taaattgatt tgaatttcaa aattaaattg tttgattctt atttcaattt gttatagtat
    20581 atctgatgtc aaagttctcg gcgaatc
//
LOCUS       DAVLBN010000038        19912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLBN010000038 DAVLBN010000000
VERSION     DAVLBN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.038"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            500..1663
                     /locus_tag="VXC24_001388"
     CDS             500..1663
                     /locus_tag="VXC24_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0493491.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1660..2337
                     /locus_tag="VXC24_001389"
     CDS             1660..2337
                     /locus_tag="VXC24_001389"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0493492.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2327..3181
                     /locus_tag="VXC24_001390"
     CDS             2327..3181
                     /locus_tag="VXC24_001390"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0493493.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3200..4267
                     /locus_tag="VXC24_001391"
     CDS             3200..4267
                     /locus_tag="VXC24_001391"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0493494.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4277..5443
                     /gene="aroC"
                     /locus_tag="VXC24_001392"
     CDS             4277..5443
                     /gene="aroC"
                     /locus_tag="VXC24_001392"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0493495.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5453..6556
                     /locus_tag="VXC24_001393"
     CDS             5453..6556
                     /locus_tag="VXC24_001393"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0493496.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6567..6905
                     /locus_tag="VXC24_001394"
     CDS             6567..6905
                     /locus_tag="VXC24_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0493497.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6997..8280
                     /gene="aroA"
                     /locus_tag="VXC24_001395"
     CDS             6997..8280
                     /gene="aroA"
                     /locus_tag="VXC24_001395"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0493498.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8273..8749
                     /locus_tag="VXC24_001396"
     CDS             8273..8749
                     /locus_tag="VXC24_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0493499.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8746..9594
                     /gene="pheA"
                     /locus_tag="VXC24_001397"
     CDS             8746..9594
                     /gene="pheA"
                     /locus_tag="VXC24_001397"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0493500.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9591..10865
                     /gene="psr"
                     /locus_tag="VXC24_001398"
     CDS             9591..10865
                     /gene="psr"
                     /locus_tag="VXC24_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0493501.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11144..11989
                     /locus_tag="VXC24_001399"
     CDS             11144..11989
                     /locus_tag="VXC24_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0493502.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11979..13082
                     /locus_tag="VXC24_001400"
     CDS             11979..13082
                     /locus_tag="VXC24_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0493503.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13084..14070
                     /locus_tag="VXC24_001401"
     CDS             13084..14070
                     /locus_tag="VXC24_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0493504.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14086..15522
                     /locus_tag="VXC24_001402"
     CDS             14086..15522
                     /locus_tag="VXC24_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0493505.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15551..16585
                     /locus_tag="VXC24_001403"
     CDS             15551..16585
                     /locus_tag="VXC24_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0493506.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16727..17464
                     /gene="mecA"
                     /locus_tag="VXC24_001404"
     CDS             16727..17464
                     /gene="mecA"
                     /locus_tag="VXC24_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0493507.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFARTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17615..18901
                     /locus_tag="VXC24_001405"
     CDS             17615..18901
                     /locus_tag="VXC24_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0493508.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18903..19772
                     /locus_tag="VXC24_001406"
     CDS             18903..19772
                     /locus_tag="VXC24_001406"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0493509.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
BASE COUNT         5926 a         3600 c         4528 g         5858 t
ORIGIN      
        1 aacgttaatt cctataatgt gtgtgatcca agtatttttg atagaacata tatttagagt
       61 tcgaaataga atgatgcaaa taggtgaaat tttaattatt gttgcttcta taatattatt
      121 tattgatagt atattgagtt tgtaacaaaa ggcttttcta taaaatcaaa ttttccagat
      181 atctactgaa gctgatttat ttcttcatct ttcttctact acctttgtca ctaaatttga
      241 cagacacata ttgctgatac aacctctcta cctataatct cacggttaac ctgaggctag
      301 tttcatagtt tgctatttga ttttcgttga taaaaagaaa tgctcctcca agacggaaga
      361 gcatttttta ctgtgattct tacacattta cttcctagtt ttgcaggaag tctagtatac
      421 cattttttaa aagaagagta aaaaagcaag ggtagtttct tttttgagaa ttgtctaaaa
      481 gtttgatata atggtagtta tgaatagaat aagagtcagc aaaagggttg aaaagaagct
      541 tgctaagggg ctagttttac tagaagccag tgatcttgag aatgtcaatc ttaaggatca
      601 ggaagtagag gtgcagggtc aggaaggaaa ctttcttggg actgcctacc tttctcagca
      661 aaacaagggc ttgggctggt ttatcagcaa agacaaggtg gccttcaatc aagctttctt
      721 tgaaacgttg tttagaaaag ccaaagaaaa gagaaacgcc tactatcaag atgatttgac
      781 aactgccttt cgtctcttta atcaagaggg agatggcttt gggggtctga cagtggacct
      841 ttatggcgac tacgccgtct tttcttggta taactcttat gtttatcaga ttcgtcagac
      901 tatatcagaa gcctttagac aggttttccc tgaggtttta ggagcttatg agaaaatccg
      961 ctttaagggt ttggactatg aatctgccca tgtttatggt caagaagcac ctgacttttt
     1021 cactgtttta gaaaatggtg tcctgtatca agtctttatg aatgatggct tgatgacagg
     1081 aattttccta gaccagcatg aggttcgcgg tagtttagtt gacggcttgg ctatgggtaa
     1141 atccttgctc aatatgtttt cctacacagc ggctttttca gtagctgcgg ccatgggagg
     1201 agctagccag acaacttctg ttgatctagc caaacgttca cgagaattgt ctcaagcgca
     1261 ttttcaggca aatgggctca gcacagacga gcatcgtttt atagtcatgg atgtctttga
     1321 gtatttcaaa tatgccaaac gcaaagactt gacctacgat gtgattgtcc tagatccgcc
     1381 tagctttgct cggaataaaa aacaaacttt ctctgtggcc aaggattatc acaagttgat
     1441 ttcccagagt cttgagattt taaatccggg agggattatc attgccagta ccaatgctgc
     1501 caatgtttcc cgtcagaaat ttacagaaca aattgataaa ggttttgcag gaagaagtta
     1561 ccagatttta aacaaatatg gtcttccagc agattttgcc tataataaaa aagatgaaag
     1621 tagtaattac ctcaaggtga ttagtatgaa ggttagtaaa tgaaattaat cgtttcagta
     1681 atgccaagaa gtttagagga ggctcaggct ctggatgcca cgaggtacct ggatgccgac
     1741 atcattgaat ggcgtgccga ctatctgcct aaagaagcga ttttgcaggt agctccagcc
     1801 atttttgaaa aattcgcagg ccgtgagttg gttttcacgc tacgaactcg ctccgaaggt
     1861 ggagaaatcg acctttctcc agaagagtat atccatctaa tcaaggaagt tgcgcaactc
     1921 tatcaaccag actatattga ttttgagtac tatagctaca aggatgtttt tgaggaaatg
     1981 ctggacttcc caaatcttgt tttgagttac cataatttcc aagaaacacc tgagaacatg
     2041 atggaaatct tgtcagagtt gacgatccta aatccaaaac ttgttaaggt tgcggtgatg
     2101 gctcacacgg agcaggatgt cttagacttg atgaactata cacgaggctt taaaaccctc
     2161 aatcctgaac aggaatatgt gaccatttct atgggtaagg tgggcaaggt ctctcgtatc
     2221 actgcggatg tgactggttc gagttggtct tttgccagtc tggatgaggt tagtgcccct
     2281 gggcagattt ctctagctag catgaaaaaa atcagggaga ttttggatga agcttgatgg
     2341 ctatacacgt ttagctgcag ttgttgccaa tcctattaag cattctattt ctcccttcat
     2401 ccacaataga gcctttgagg cgacagctac caacggtgct tatgtggctt gggagattga
     2461 agcgagtgac ttggcagaaa cagtggccaa tattcgtcgc taccagatgt ttggcatcaa
     2521 tctgtccatg ccctataagg agcaggtgat tccttatttg gataagctga gcgatgaagc
     2581 gcacttgatt ggtgcggtta atacggttgt caatgagaat ggcaatttaa ttggatataa
     2641 tacagatggc aagggatttt ttaagtgctt gccttctttt acaatttcag gtaaaaagat
     2701 gaccctgctg ggtgcaggtg gtgcggctaa atcaatcttg gcacaggcta ttttggatgg
     2761 cgtcagtcag atttcggtct ttgttcgttc cgtttctatg gaaaaaacaa gaccttacct
     2821 agacaagtta caggagcaga caggttttaa agtggatttg tgtgctttag aatatgtttc
     2881 tgaactgcaa gcaaggattg ccgagtcgga tttgctagtt aatgccacca gtgtgggcat
     2941 ggatggccaa tcctctcctg ttcctgaaaa catagtctta ccagaaactc tcttagttgc
     3001 agatatcata taccaaccct ttgaaacacc gtttttgaaa tgggctagaa gtcagggcaa
     3061 tccagcagtc aatggtctgg gaatgttgct ctatcaagct gcagaagctt ttcaactgtg
     3121 gacaggcaag gaaatgccga cagaagagat ttggcagtct ttaacagaaa aataccaata
     3181 aagaaaggga gactctccta tgaaaatcag aatcgatatt cctcatcatc cttatgatat
     3241 tcagattgaa aaaggttgta tggcccaggc tggtcagtgg ttgcgagaac tctggcaacc
     3301 gcaaaaggta gtcattgtga cagataacca tgtagcctct ctctatgcag agaaggtcaa
     3361 gctcagccta gaagatgctg gttttcaggt agctgttttt gatttcttag aaggtgaaga
     3421 aagaaagaat ttaactactg ttcagaaagt ctatgaattt ctagtcaagc aaggtctgac
     3481 tcgtagcgat ggaatcgttg ctcttggtgg tggcgttgtt ggggacctgg ctggatttgt
     3541 agcctctacc tatatgcggg gtattcactt tgttcagatt ccgactagtt tgacagctca
     3601 ggttgattct tctatcggtg gaaagacagg cgttaacaca ccatttgcta aaaatatggt
     3661 ggggaccttt gcccaaccag atggggttct gattgatcca cttgttcttg aaaccctcgg
     3721 aaaaagagag ttgattgaag ggatgggtga agttatcaag tatggcttga ttgaggatcc
     3781 agaactgtgg gctctcttga cgggactgaa tggttctgtt gagagtattt tggaacatgc
     3841 agagaccttg attgaacatt cttgtcaggt gaagcgcaag atggtggttg aagatgagtt
     3901 ggacaatggt attcgtcttt acctcaattt tggccacact attggccatg ccatcgaagc
     3961 gactgccggt tatggcaagg tcatgcatgg agaggctgtt gccatgggaa tggtacagat
     4021 ttccaaggtt gctgaggaaa aaggcctcat gccagctggc attacccaat ctatcacaga
     4081 gatgtgtcag aaattcggct tgcctgttga ctatgaaaat tggaaagttg acaagcttta
     4141 tcaggctctt actcatgaca agaaagcgcg tggtaacacc ttgaaattgg tcttggtgcc
     4201 agagcttggt tcagcgacca ttcacccagt ttctctggaa gagatgaaag actacttggt
     4261 aaaataagga gagtgtatga gatatttaac tgcaggagaa tcacacggcc cccgtctaac
     4321 agctattatt gagggaattc cagctggact tccattgaca gctgaggata tcaatgagga
     4381 tcttagacgc cgtcagggtg gctacggtcg tggtggtcgt atgaagattg agagtgacca
     4441 ggttgtcttt acttcgggtg ttcgccacgg gaagacgaca ggggcgccta ttactatgga
     4501 tgtcatcaat aaggaccacc agaaatggct ggacatcatg tctgcggagg acattgaaga
     4561 ccgccttaaa agcaagcgga aaattactca tcctcgccca ggtcatgccg atttggttgg
     4621 ggggattaag taccgttttg atgatttgcg aaattctttg gagcgttcat cagctcgtga
     4681 aaccaccatg cgggtggcag ttggtgcagt agccaaacgc ctcttggctg agctggatat
     4741 ggagattgcc aaccatgtcg tggtctttgg tggtaaggaa atagatgttc ctgaaaatct
     4801 gacagtcgct gaaattaagc aaagagctgc ccagtctgaa gtttctattg tcaaccaaga
     4861 acgagaacag gaaatcaagg actatattga ccaaatcaaa cgtgatggtg ataccatcgg
     4921 tggggttgtg gagacagtcg tcggaggagt tccagttggt cttggttcct atgtccaatg
     4981 ggatagaaaa ttggatgcaa gattggctca agctgttgtc tctatcaatg cctttaaagg
     5041 ggtggaattt ggtcttggct ttgaggctgg ttatcgtaaa ggcagccaag ttatggatga
     5101 aattctctgg tctaaagaag acggttatac tcgccgtacc aataatctag gtggttttga
     5161 aggtggtatg actaatgggc aacccatcgt tgttcgtggg gtcatgaaac ccattcctac
     5221 tctttataaa cctcttatga gtgtggatat cgaaacccac gaaccttaca aggcaaccgt
     5281 ggagagaagt gatccgactg ctcttccagc tgcaggaatg gtcatggaag cagttgtagc
     5341 aacggttctg gcgcaagaga tcctcgaaaa attctcatca gataatcttg aggaactaaa
     5401 agaagcggta gccaaacacc gagactatac aaagaactat taaggagttc ctatggcaaa
     5461 aacaatctat atcgcaggtc ttgggttgat tggagcctct atggcacttg gtatcaaacg
     5521 cgatcatcca gattatgaaa ttttaggtta taatcgtagt caagcttcga gagatatcgc
     5581 cttgaaagaa ggcatgattg accgtgcaac ggatgatttt gctagttttg ctcctttggc
     5641 agatgtcatt atcctcagct tgccaatcaa acaaactatt gctttcatta aggagttggc
     5701 caatttggat ttgcgagaag gcgttattat ttcagatgct ggttcgacca agtcaaccat
     5761 tgtggatgcg gcggagcagt atttggctgg caagtctgtt cgctttgtcg gggcccatcc
     5821 catggctggt agtcacaaga caggggctgc ttcggcagat gtcaatcttt ttgaaaatgc
     5881 ctattatatc tttacacctt caagcctgac aagtcaggac acgcttaagg aaatgaagga
     5941 tctgctttca ggtcttcatg ctcgttttat cgagattgat gccaaggagc atgatcgtgt
     6001 cacttctcag attagccatt ttcctcatat tttggcttct agtctcatgg agcagactgc
     6061 ggtctatgct caagagcatg agatggcaag gcgctttgcg gcaggtggtt ttcgagatat
     6121 gacccgaatt gcggaaagcg agccaggaat gtggacctcc attctcttgt ccaatagcga
     6181 gaccattctg gatagaattg aggatttcaa ggaacgtttg gaatcgattg gtcaggccat
     6241 tagtaaggga gatgaagagc aaatttggaa cttttttaac caagcgcgtg aacaacgcca
     6301 gaccatggaa atccataagc gtggtggtgt ggatagctct tacgacctct atgttgacgt
     6361 tcctgatgaa gaagatgtca tcctgcggat tttggaactg ctacgtggga cttccttggt
     6421 taacatccac atcaacgagg aaaatcgtga ggatattcac ggaatcctac aaatttcatt
     6481 taaaaatgct caagacttgg aaagagccga gcatctcata acaaaaaata ccgactatac
     6541 agtcgtcatt aaataaggag aagaacatgt caaatattta cgatagtgca aacgaactca
     6601 gtcgcggtct acgcggatta ccagaataca aggctgttaa agcagctaaa gatgcgattg
     6661 cagcagatgc tgaggcaagc aaaatcttta cagaatatct tgcctttcaa gaggaaattc
     6721 aaaaactagc acagacaggt caaatgccag atgcgtcctt ccaagctaag atggaaggct
     6781 ttggtaaaca gattcaagga aatagcctct tgtcagaatt ctttaccaag caacaacaat
     6841 tggccattta cctttctgac attgaaaaaa ttgttttcga accagtttca gaattgctga
     6901 aataagaaaa gaactatcct aaagtcagga atttttaagg aatttctggc tttttatgat
     6961 aaaataggta aaagtattgc aagtatgagg tccagtatga aactaaaaac aaatattcgc
     7021 catttacatg gtagtatccg cgtcccaggt gacaagtcta tcagccaccg ttccattatc
     7081 tttggaagtt tggctgaggg tgagaccaag gtttatgata ttctgcgagg tgaagacgtt
     7141 ctttcgacca tgcaggtttt tcgtgacctt ggtgttgaaa ttgaggataa agatggggtt
     7201 attaccattc aaggtgtagg catggctggc ttaaaagcgc cgcaaaatgc ccttaatatg
     7261 ggaaattctg gcacctcgat tcgcctgatt tcaggtgtcc ttgctggtgc agatttcgaa
     7321 gtagagatgt ttggagatga tagtctttcc aaacgtccta tggaccgtgt gacccttcca
     7381 ctgaaaaaaa tgggcgtcag catctcaggg caaactgaac gagacttgcc tccccttcgc
     7441 ttaaaaggga cgaaaaacct aagacctatt cattatgagt tgccaattgc ctctgcccaa
     7501 gtcaagtcag ccttgatgtt tgcagcctta caagctaagg gggagtcagt tattatcgaa
     7561 aaagagtgca cccgtaatca tactgaagat atgttgcaac aatttggtgg ccatttaagt
     7621 gtggatggca agaaaatcac agttcaagga cctcaaaaac tgactggaca aaaggtggtc
     7681 gtaccaggag atatttccag tgcatccttt tggttagtcg caggtttgat tgtcccaaat
     7741 tctcgtttag tgctgcagaa tgtggggatc aacgaaactc gcaccggtat tattgatgtc
     7801 attcgtgcca tgggtggaaa attggaaata actgaaatcg atccagtcgc taaatctgct
     7861 accttgattg ttgagtcttc tgacttgaaa ggaacagaga ttggtggcgc tttgattcca
     7921 cgattgattg atgaattgcc cattattgcc ctgcttgcga ctcaagccca aggtgtaaca
     7981 gttatcaagg atgctgagga gctcaaggtc aaggaaacag accgtattca ggttgtggca
     8041 gacgccttaa atagtatggg agcagatatt actcctacgg cagatgggat gattatcaaa
     8101 gggaaatcag ctcttcacgg tgctagagtc aatacgtttg gtgaccaccg tatcggcatg
     8161 atgacagcta tcgcagccct cttggttgca gatggagagg tggagcttga ccgtgcagaa
     8221 gccatcaata ccagctatcc tagtttcttt gatgatttgg agagcttgat tcatggctaa
     8281 ggtgttatta gggtttatgg gggctggaaa atcgactatt gcaagaggct tggaccctaa
     8341 ttaccttgat atggatgctc tgattgagaa gcgcctaggt atgtccattg cgaatttttt
     8401 cgctgaaaag ggagaagcag cctttcgtca ggtagaatca gaagtcctag ctgatttact
     8461 acaaacagac caagtcgtgt caactggagg aggagtggtt atttctcaga gaaatcgtga
     8521 cttactcaag actaatacag ataacatcta cctgaaagca gattttgaaa ccctctacct
     8581 acgtatcgca gctgataagg acaatcagcg accgcttttt ctaaataata gcaaggaaga
     8641 actagtagct atttttcaag aaagacaggc ttggtatgag gaagtggcta gtcgggtttt
     8701 ggatgtgacc aagctaagcc cagaggaaat tatagaggaa ctaagatgaa aatagcttat
     8761 ctaggtccca agggatcatt ttcacaccac gttgtgcaga cagcttttcc tcatgaggaa
     8821 ttgcaggctt ttgccaacat tacagatgtc atcaaggctt atgagcaagg attagtgaac
     8881 tattctgtgg tgccagttga aaattctatt gagggtagtg ttcatgaaac cttggactat
     8941 ctttttcatc aggctcacat ccaagcagta gcagaaatcg ttcagcctat tcatcagcag
     9001 ttgatggtgg ttccaggcca tactaagatt gaaaagattt tttcacatcc acaggccttg
     9061 gctcaaggaa agaaattcat cgatgaacaa tatccagagg ctcaaatcga ggtaacagct
     9121 agtacagctt atgcggcccg ttttatttcc gaacatccag atcagccctt tgcagcagtt
     9181 gcacctagaa gttctgctga agaatatgga ttggaactga ttgccgagga tattcaggaa
     9241 atggaagcca atttcacacg tttttgggtt ttgggagctg aaggtgtaac tattcccttg
     9301 caatcacaaa ctgaaaaaat gagtttagcc ttgaccctac ctgacaacct tccaggtgca
     9361 ctttataaag ccctgtcgac ctttgcttgg cgaggaattg acttgacaaa aattgaaagt
     9421 cgtccactca agacagcact gggtgaatac tttttcatta tcgatgtgga ttataccgat
     9481 aaggacttgg tccactttgc ccaaaaagaa ttagaagcga ttggaatcca gtataaaatt
     9541 ctgggtgcct atcctattta tccaatatca gaccatggaa aggagagaag atgagtaaag
     9601 aaaatccctt aagtcatcat gagcagttgc gttatgatta tttgctaaaa aatattcact
     9661 atctcaatga gagagaaaaa aatgagtttg cctatttgca agaaaagcta actcttgcta
     9721 ggggaaatag tagctctagc ttggaacaag aaagagaaga gcaggttgac ttaccaagct
     9781 atgcgaaccg gagtcgctca caatccaaat cacaagcact ctctttccct ccaaaaaaga
     9841 aaagacggaa gctccgtctt aaacgaattt ttatggtgat tttttcactt ttggtctgtg
     9901 tggctttggc catggtattc atgtttttgc gtggttacca agatgctagc gcaaagaaaa
     9961 ctgctgatgc ccgggcagct caagtagaag tatttaatgg tcaggacact agagatggag
    10021 ttaatatttt aatcatgggt actgatggtc gaatcggcca gaacagtgtt gagacacgaa
    10081 ctgactctat tatggtatta aatgtcgggg gctcagataa gaaaatgaag ctagtcagtt
    10141 tcatgcgtga taatttggtc tatatagatg gttatagtca agtgattaat ggtagaaaac
    10201 agacagataa caagttaaac gtagcctacg agttaggaga acaagagggg caaaaagggg
    10261 cagaaatggt tcgccaagtc ttgaaagata attttgactt ggacattaag tactacgcct
    10321 tggttgattt ccaggccttt gccacagcga ttgacacgct tttccctgat ggggtgacga
    10381 ttgatgctca attttcaaca ttgaatgggc gtcccctaac agaagctaca gtcggagatg
    10441 atttatatgc taccgagact gagtctccaa cccaaaccat taaagtcgga aaacagcaga
    10501 tgaatggctc gaccctgctc aattatgctc gtttccgtga tgatgatgag gcggattacg
    10561 gccgtacaaa aagacagcaa caagttttaa cagcaatttt agagcaaatt aaagatccca
    10621 ctaaactttt cactggttct gaagctcttg gaaaggtttt tgctatgacc tcaaccaacg
    10681 taccctatac tttcctccta acaaacggtt tatctgtttt ggatggagca aaaaatggta
    10741 ttgaaaaatt gacgattcca gaactgggtg actgggtaga tgcctatgat gtttatggag
    10801 gcttgggctt gctggttgat caaaacaaat atcaaaccaa gctcgctcaa atgggcttga
    10861 gataagataa tactcaatga aaattaaagt gcaaactagg aagctagccg caggctgcta
    10921 aaaacacagt tttgaggttg tagataagac tgacgaagtc agttacctat acctacggca
    10981 aggtgaagct gacgtggttt gaagagattt tcgaagagta taagacagaa aaatcaaagt
    11041 ttgatagcta tttggatagc agtcaggctt tgatttttta cagtctgcaa tagattttca
    11101 ccccttgttt gtggtataat gaaacgatac gatagaaaga ataatgaaca atatgactga
    11161 tttaaaagca attcaggctc gtagtctgga gatggctgaa tattttgtgg ccttttgtaa
    11221 agaacatgat ttgctctgtt atctctgtgg cggaggcgct attggtaccc ttcgaaacaa
    11281 gggatttatt ccttgggacg acgacctaga cttttttatg cctcgtaaag attatgagaa
    11341 attagcagaa ttatggcctc gttatgcaga tgaacgttat ttcttgtcaa agagttacaa
    11401 ggattttgtt gatcgtaatc tttttattac cattcgtgac aaggaaacca cctgtatcaa
    11461 gccttatcag caggatttgg atttgccaca tggtctggcc ttggatgttt tgcctttgga
    11521 ttattatccg aaagatccag ctgagcggaa aaaacaggtt cgttgggcct tgatttattc
    11581 actcttttgt gcgcaaacta ttccagaaaa gcatggtgct ctcatgaaat ggggaagtcg
    11641 cattttactg ggtttgactc caaaatctct ccgttatcgc atctggaaaa aagctgagaa
    11701 agaaatgact aagtatgatt tggctgattg tgatggcatt acagaattat gctcaggtcc
    11761 tggctacatg agaaacaagt acccaatcac atcttttgaa gacaatcttt tcttgccatt
    11821 tgaaggaaca gagatgccta ttccaatcgg ctatgatgtc tatctcagaa ctgcttttgg
    11881 ggattatatg acgcctccac cagcagacaa gcaggtaccg catcatgatg ctgtcatcgc
    11941 tgatatggat aagtcttata cagaatacaa gggagaatat ggtggctaag aaaaaaatct
    12001 tattttttat gtggtctttt tctcttggag gtggtgcaga gaagattcta tcaaccattg
    12061 tttcaaatct ggatctagaa aagtatgata ttgatattct tgaaatggag cactttgaca
    12121 agggatatga atctgttcca aagcatgtac gcattttaaa atcccttcaa gattatcgcc
    12181 aaaccagatg gttacgagct tttttgtgga gaatgagaat ttattttcca agactggctc
    12241 gtcgtttgct tgtaaaagat gattatgatg ttgaagtttc ttttaccatt atgaatccac
    12301 cactgttgtt ctctaaaaga agagaagtca agaagatatc ttggattcat ggaagtattg
    12361 aagaacttct taaggatagc tctaaaagag aatcacatag aagccagttg gatgctgcga
    12421 atacaattgt agggatttca aaaaagacca gcaattctat caaggaagtt tatccagatt
    12481 atgcttctaa attacagaca atctacaatg gatatgattt tcagactatt ctagaaaaat
    12541 ctcaagagaa gatcgatatc gagattgctc ctcaaagtat ctgtactatc ggacggattg
    12601 aggaaaataa gggttctgac cgtgtagtgg aagtgatacg attattacac caagagggaa
    12661 aaaactatca tctctatttt atcggggctg gtgatatgga agaggaactg aaaaaacgag
    12721 tcaaagagta tgggattgag gactatgtac atttccttgg ttatcaaaaa aatccttatc
    12781 agtatctatc tcagacgaaa gttctcttgt ctatgtctaa acaagaaggt tttcctggag
    12841 tgtatgtgga ggccttgagt ctgggactcc cttttatctc tacggacgtt ggaggggctg
    12901 aggaattatc ccaagaagga cgatttggac aaatcattga gagcaatcaa gaggcagctc
    12961 aggcgattac taattacatg acttctgcct caaactttga tgtcgatgag gctagccaat
    13021 tcattcaaca atttacaatt acaaaacaaa tcgaacaagt agaaaaacta ttagaggagt
    13081 agcatggaaa ctgcattaat tagtgtgatt gtgccagtct ataatgtggc gcagtaccta
    13141 gaaaaatcga tagcttccat tcagaagcag acctatcaaa atctggaaat tattcttgtt
    13201 gatgatggtg caacagatga aagtggtcgc ttgtgtgatt caatcgctga acaagatgac
    13261 agggtgtcag tgcttcataa aaagaacgaa ggattgtcgc aagcacgaaa tgatgggatg
    13321 aagcaggctc acggggatta tctgattttt attgactcag atgattatat ccatccagaa
    13381 atgattcaga gcttatatga gcaattagtt caagaagatg cggatgtttc aagctgtggt
    13441 gtcatgaatg tctatgctaa tgatgaaagc ccacagtcag ccaatcagga tgactatttt
    13501 gtctgtgatt ctcaaacatt tctaaaggaa tacctcatag gtgaaaaaat acctgggacg
    13561 atttgcaata agctaatcaa gagacagatt gcaactgccc tatcctttcc taaggggttg
    13621 atttacgaag atgcctatta ccattttgat ttaatcaagt tggccaagaa gtatgtggtt
    13681 aatactaaac cctattatta ctatttccat agaggggata gtattacgac caaaccctat
    13741 gcagagaagg atttagccta tattgatatc taccaaaagt tttataatga agttgtgaaa
    13801 aactatcctg acttgaaaga ggtcgctttt ttcagattgg cctatgccca cttctttatt
    13861 ctggataaga tgttgctaga tgatcagtat aaacagtttg aagcctattc tcagattcat
    13921 cgttttttaa aaggccatgc ctttgctatt tctaggaatc caattttccg taaggggaga
    13981 agaattagtg ctttggccct attcataaat atttccttat atcgattctt attactgaaa
    14041 aatattgaaa aatctaaaaa attacattag aacgggggtg accaagtgat tgatgggaaa
    14101 cgattattat ttagtttgac catagtcagt tatgccttga cgctagtaag tggaattgtg
    14161 tatctgttta ataataataa taatgttagc ttactttcta ctttattgtt cttgttggtt
    14221 agtagcttaa ttgcttgttg gaatgatatc aagtattact taatccattt tattttctat
    14281 ttaaccattt ttgtatttct ggtatcaaga ccgaccattg attattttag ggatggtgct
    14341 ttggatacct atcatccaat agcctatcgt tttgccttta tagttgtcat ggtttcgatt
    14401 ctgggcttga ccacaggagg cattctggct cgttacttca tagctaggaa gaaaataaaa
    14461 gtagcaaata taggaaattc tctaaaagag gtttatatca agcggttacg ctttgtatca
    14521 ctaggagttt ttcttctaac ctatcctttc tatttcattc ggttatttga acggctcttg
    14581 tatcgtttgc agacttccta ctatgcctac tatgcaaatt ttgaaagtaa actgccttat
    14641 tttacctaca ttttgtctac ctttacggtc tatgcaatgt gtatgtatct ggcaaccaag
    14701 ccaaagaaat tgcaggccac agcagtgctt gtctccttta ttgcagctaa tactattcat
    14761 ttggcaattg ggacacgaaa tccctttatt ttaagtattt tatttgcttt tgtttattac
    14821 tttatgcggg agcaaactga aaaaggaaaa tggattgggt ttaaagaaaa gttagcgatt
    14881 tttgtaggtt ctcctattct catgttagcg atgggagtac tcaattatgt acgggataat
    14941 gtccaagttt ctcatacagg tttctgggat atcttacttg actttatcta taaacaaggg
    15001 actagttttg gtgttctggc tcgaggtttt ctatttaaca gtagcctccc ttaccgagat
    15061 ttccgtaatt ttacttttgg tcctgttctt gattattttg caagggggag tttgggagcc
    15121 attttcggag gaaaagcctt tgaacataca accaatagtg tggaactagc tattgatagt
    15181 aatagttatg cccacaatct atcctatctt gtcttgaaca aggaatactt gaaagggcat
    15241 ggtatcggaa gtagttatat catggagttg tataccgact atggtatgat tggagtcttt
    15301 ctgcttagtt tcttactcgg cgtattattt atagccatgc tgcaagtagc ctatcgctca
    15361 aggacaatcc tatttgcttt atccctactc atcttgaata atctattctt tatgccaaga
    15421 agcagctttt cagaaagttt cttcaattta tttacaatgc aattctgggg aattgttctt
    15481 gtgattatat ttgtagcaaa aatgcttaca aaggaaaact agtatctact aaacaaagga
    15541 gaaaaaaatc atgtttgaac attattcagt agctgatttg tttgcaaatc tttataaaaa
    15601 acgaaaagca aatattttag ctctcatcgc tttatttgct ctcattgctg taccatttac
    15661 aattaaagca gttaggaata aaaacactgt caaagataca acaagttatt caacttatct
    15721 tatctataaa atcactcctc caaaagagtc ggccaaaacg attttgaatc atcaaattgg
    15781 tggttatagt gatttttatg ggaaattgat tgatggtaat ttgaatggag cttatctttt
    15841 caatgatgta gaacccagtg agttgaaaaa aattgccagt gaattagaca cgacagaaac
    15901 aaccttgaaa aattcaacga atgactattg gtggaaaaaa ttgaccgtct actatatgat
    15961 tgacgatgca ggggttggtg tgaaaatttt gacatcaagt aaagatgcca atgacttgtt
    16021 agagaaaaaa attgatgggt tgattgagaa atttaaacat gcctatgcaa atgtgaaaat
    16081 tgaaaaactg gaaaccatca actctaaaga attgaacgca aatggtgaaa cagcgcttgg
    16141 cttaaatgtg aaaaatctga ttcttcgttt agttgttatt ggagtggttt gtgtgatttt
    16201 ggttgtgatg ggaaatgtgt tagtttatct ctttaatcca acaatcaata gagtaggtga
    16261 tttttctcag tatcaaattg attttgtaac agagattaca acaattgcta acctagcaga
    16321 tgttttgtca tacaaaaata ctggacagga attgaccatc gttagctcaa ataaagctat
    16381 cctagataaa ttgaaacaga gtcaagaagc tttaaaagga atgcattttg tagatttaca
    16441 ggatgtatca tctcttttgg aaagagatac agtccttctt gttgaagagt acggagtgac
    16501 tcgttataag aaatttgagc aaagtcttca aattctcaga aacttaaatc gttctatcct
    16561 cggtgtagca acctttaaat tataagtatt ctgatgtata aggtcttcaa agtcggctaa
    16621 gagccgattt tgaaggcttt ttctatctgt ctgcagaaat tttcttttga taaaatcgta
    16681 aaaatctagt ataatagata gaactgaaag tatgaggtta ctagcaatga aaatgaaaca
    16741 aattagtgat acaactttaa aaatcacgat atctttagag gatttgatgg atcgtggaat
    16801 ggagattgct gactttctcg ttcctcaaga aaaaacagaa gagttctttt atgctatctt
    16861 ggatgagcta gagatgcctg atagctttct ggatacaggc atgttgagct tccgtgtgac
    16921 tccaaaacct gataaggtag atgtctttgt gaccaagtca aagattgacc aaaatctaga
    16981 ttttgaagac ttatcggatt tgccagatat ggaagaattg gctcaaatgt ctccagatga
    17041 atttatcaaa accctggaaa aaagcatcgc agacaaaacc aaggatgata tcgaagccat
    17101 tcaatctctt gagcaagttg aagccaagga agaagagcaa gagcaggctg aacaagaagc
    17161 tgagagtaag aaagaacctt acatctacta catcctttct tttgctaagt tggctgactt
    17221 ggtagctttt gccaggacag tgacttttga aatggaaact tctgaactct acaaaatgaa
    17281 cgagcgctat tatttgacca ttttagtgga tattgaaaat catccaagcc catatccagc
    17341 ttggctgttg gcccgtatgc gcgagtttgc agacgatagt gatatcagtc gctcagtctt
    17401 acaagagtat ggtcaagtct tgatgagtca cgatgcagtg ctcaatctgc aaaaaatcgg
    17461 ctaatccttt ctggaaagct attttcagat tttaagaaga gcgaatcgtc tgattcgttt
    17521 tttcttttta tactgaaata gtgatttact ataataggaa ttttcacaaa attctgttat
    17581 aatggctata ttagaaaatt tcgaggagat aaagatgaca gttaaaattg ctttactagg
    17641 atttggtacc gttgcaagtg gtgtgccttt cctcctaaag gaaaatggag gaaaaatcaa
    17701 tcaatcagca cattcagata tcaaagttgc taaggtattg gtcaaggatg aagatgaaaa
    17761 aaatcgcttg cttgcagcag ggaatgactt taactttgta accaatgtgg atgatatttt
    17821 atcagaccag gatattacta tcgtagtgga attgatgggg cgtattgagc ctgctaaaac
    17881 ctttatcact cgtgccttgg aagctggaaa acacgttgtt actgctaaca aggacctttt
    17941 agctgtccat ggcgcagaat tgctagaaat cgctcaagct aacaaggtag cactttacta
    18001 cgaagcagca gttgctggtg ggattccaat tcttcgtact ttagcaaatt ccttggcttc
    18061 tgataaaatt acgcgcgtgc ttggagtagt caacggaact tccaacttca tggtgaccaa
    18121 gatggtggaa gaaggctggt cttacgatga tgctcttgcg gaagcacaac gtctaggatt
    18181 tgcagaaagc gatccgacga atgacgtaga tgggattgat gcagcctaca agatggttat
    18241 tttgagccaa tttgcctttg gcatgaagat tgcctttgat gatgtagccc acaagggaat
    18301 ccgcaatatc acaccagaag acgtagctgt agctcaagag cttggttacg tagtgaaatt
    18361 ggttggttct attgaggaaa cttcttcagg tattgctgca gaagtgactc caaccttcct
    18421 acctaaagcg cacccacttg ctagtgtgaa tggcgtaatg aacgctgtct ttgtagaatc
    18481 tatcggtatt ggtgagtcta tgtactacgg accaggtgct ggtcaaaaac caactgcaac
    18541 aagtgttgta gctgatattg tccgtatcgt tcgtcgtttg aatgatggta ctattggcaa
    18601 agacttcaac gaatatagcc gtgacttggt cttggcaaat cctgaagatg tcaaagcaaa
    18661 ctactatttc tcaatcttgg ctctagactc aaaaggtcag gtcttgaagt tggctgaaat
    18721 cttcaatgct caagatattt cctttaagca aatccttcaa gatggcaaag agggtgacaa
    18781 ggcgcgtgtc gttatcatca cacacaagat taataaagcc cagcttgaaa atgtctcagc
    18841 tgaattgaag aaggtttcag aattcgacct cttgaatacc ttcaaggtgt taggagaata
    18901 agatgaagat tattgtacct gcaaccagtg ccaatatcgg gccaggtttt gactcggtcg
    18961 gtgtagctgt aaccaagtat cttcaaattg aggtctgcga agaacgagat gagtggctga
    19021 ttgaacacca gattggcaaa tggattccac atgatgagcg taatctcttg ctcaaaatcg
    19081 ctttgcaaat tgtaccagac ttgcaaccaa gacgcttgaa aatgaccagt gatgtccctt
    19141 tggcgcgcgg tttgggttct tccagctcgg ttatcgttgc tgggattgaa ctagccaacc
    19201 aactgggtca actcaactta tcagaccatg aaaaattgca gttagcgacc aagattgaag
    19261 ggcatcctga caatgtggct ccagccattt atggtaatct cgttattgca agttctgttg
    19321 aagggcaagt ctctgctatc gtagcagact ttccagagtg tgattttcta gcttacattc
    19381 caaactatga attacgtact cgcgacagcc gtagtgtctt gcctaaaaaa ttgtcttata
    19441 aggaagctgt tgctgcaagt tctatcgcca atgtagcggt tgctgccttg ttggcaggag
    19501 acatggtgac cgctgggcaa gcaatcgagg gagacctctt ccatgagcgc tatcgtcagg
    19561 atttggtaag agaatttgcg atgattaagc aagtgaccaa agaaaatggg gcctatgcaa
    19621 cctacctttc tggtgctggg ccgacagtta tggttctggc ttctcatgac aagatgccaa
    19681 caattaaggc agaattggaa aagcaacctt tcaaaggaaa actgcatgac ttgagagttg
    19741 atacccaagg tgtccgtgta gaagcaaaat aaagaataga agataggatg gggaaactct
    19801 tgaccagagg gtttcatatc ctttttgtga aaagaagttt atactcaatg aaaatcaaag
    19861 agcaaactag gaagctagcc gcaggctgct caaaacagtg ttttgaggtt gt
//
LOCUS       DAVLBN010000039        19669 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLBN010000039 DAVLBN010000000
VERSION     DAVLBN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.039"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..675
                     /locus_tag="VXC24_001407"
                     /pseudo
     CDS             1..675
                     /locus_tag="VXC24_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(739..1821)
                     /locus_tag="VXC24_001408"
     CDS             complement(739..1821)
                     /locus_tag="VXC24_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0493510.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1818..2795)
                     /locus_tag="VXC24_001409"
     CDS             complement(1818..2795)
                     /locus_tag="VXC24_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0493511.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3010..3387
                     /locus_tag="VXC24_001410"
     CDS             3010..3387
                     /locus_tag="VXC24_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0493512.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3622..5013
                     /locus_tag="VXC24_001411"
     CDS             3622..5013
                     /locus_tag="VXC24_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0493513.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5127..5969
                     /locus_tag="VXC24_001412"
     CDS             5127..5969
                     /locus_tag="VXC24_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0493514.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6242..7003
                     /locus_tag="VXC24_001413"
     CDS             6242..7003
                     /locus_tag="VXC24_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0493515.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7196..8113
                     /gene="glyQ"
                     /locus_tag="VXC24_001414"
     CDS             7196..8113
                     /gene="glyQ"
                     /locus_tag="VXC24_001414"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0493516.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8325..10361
                     /locus_tag="VXC24_001415"
     CDS             8325..10361
                     /locus_tag="VXC24_001415"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0493517.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10403..10660
                     /locus_tag="VXC24_001416"
     CDS             10403..10660
                     /locus_tag="VXC24_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0493518.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10883..12127)
                     /locus_tag="VXC24_001417"
     CDS             complement(10883..12127)
                     /locus_tag="VXC24_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0493519.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12146..12751)
                     /locus_tag="VXC24_001418"
     CDS             complement(12146..12751)
                     /locus_tag="VXC24_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0493520.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12811..13734)
                     /locus_tag="VXC24_001419"
     CDS             complement(12811..13734)
                     /locus_tag="VXC24_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0493521.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14028..15407
                     /locus_tag="VXC24_001420"
     CDS             14028..15407
                     /locus_tag="VXC24_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0493522.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15559..16434
                     /gene="pdxS"
                     /locus_tag="VXC24_001421"
     CDS             15559..16434
                     /gene="pdxS"
                     /locus_tag="VXC24_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0493523.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16435..17019
                     /gene="pdxT"
                     /locus_tag="VXC24_001422"
     CDS             16435..17019
                     /gene="pdxT"
                     /locus_tag="VXC24_001422"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0493524.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            17576..18307
                     /locus_tag="VXC24_001423"
     CDS             17576..18307
                     /locus_tag="VXC24_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493525.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            18325..19641
                     /locus_tag="VXC24_001424"
     CDS             18325..19641
                     /locus_tag="VXC24_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0493526.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSSIILFLLIIHILIIQSLSPSIQMFLIKFLMRIFPTENYVINTGFWNLLSN
                     PSYLKSIQTSMSMGVTLISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIIT
                     SSISLTILSSNKDIEDIKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILI
                     LVSIIGQFLGRSLVDISGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT         6075 a         3495 c         4183 g         5916 t
ORIGIN      
        1 tctatcaact gttgaagcac catggttggc gaaatattat gccacgtcca gaacatccta
       61 ggaaagcaga cgctcaaacc attgtcgcgt ctaaaaataa aatctcaatt caagaagaca
      121 agaaagcgct ttaaaaccag tagacctttt cataaggttc gcttgatgta ccaagatgag
      181 gctggtttcg gtagaatcag taaactggga tcttgttggt ctccaatagg agtaggtcca
      241 catgtccata gtcactatat acgagaattt cgctattgtt atggagctgt tgatgcccca
      301 tacaggcgaa tcatttttct taatagctgg tggatgtaat actgagtgga tgaacgtctt
      361 tttagaagag ctttcacaag cttatccaga tgattatttt ttactcgtta tggacaatgc
      421 tatatggcat aaatcaagta ccttaaagat tccgactaat attgatttta cctttattcc
      481 tccatacaca ccagagatga acccattgaa caagtgtgga aagagattcg taaacgtgga
      541 tttaagaata aagcctttcg aactttggaa gatgtcatga atcaactcca agatgtcata
      601 caaggactgg agaaggaggt gataaagtcc atcgttaatc ggagatggaa tagaatgctt
      661 tttgaaagca gatgagtata aaattgaatt gcttataaaa aagctccata cactggatgt
      721 gtatagagca atggggcttt atttgatata gagttcttgg ttttttagga caatttctcg
      781 gatacttgca aactttttaa gttttttgat ttcttctgga tgagtgacga gagtaataac
      841 atatccttcc ttgcccatac ggccagtacg gccagcacgg tgtgtgtagg tttcgctatc
      901 tctaggaata tcaaagttta cgacacattc taggctatcg atatcaattc cacgagccaa
      961 aaggtcagtt gcaagaagca gggttagttg gttatcttta aacttttcta agatgatttt
     1021 tctaaattta acattaacat cactagcgag ggaaacagcc aatatatcac gatactgtag
     1081 tttttcctcg gcattcccaa ggtctgacag gctattgaag aagactagac cacggaaatc
     1141 ctctacatga gccagttttc gcagcatatc cactcgatga cgttggtcta cctgcatgta
     1201 gaaatgctgg atattgtcca atttttgatc agagagatca atagtgcgtg tattcggcac
     1261 aatcttttct tggtcaaact tggtcgtggc actcatgtag accagttggt ggtcacgagg
     1321 tgcgtagtga gtgatttttt ctacaaagtg aatctgagaa tcatctagta attggtcaaa
     1381 ttcatccagg atgatggttt ccacattcat catcttgatt tttttaagtt taatgagttc
     1441 aaagatacgg ccaggagttc caatcagaat ttctggcccc tttttaagac gttcaatttg
     1501 tcgtttctga cttgaacctg aaaggaagag ttgagcagtc aatccgatag cttctgccca
     1561 cgttttacat acatcaaaaa tctgtccagc aagttccgta tttggtgcta gaatcaagag
     1621 ttgttgggct tttttctttt gtagtctgag aagacttggt aggagatacg ctagggtctt
     1681 accagttccg gtttggctca ctcctaggag gttttctcca gcaagaaggg gctcaaatag
     1741 ttgagtttga atgggggtga attcttggaa accgagttgg tcactcagtt cttgccattc
     1801 agtcggtagt ttggttttca tttttctgcc tcaaatctaa tgccagcagt ctggcgcatg
     1861 gtatatagta gctcatgaac agagcctgca tcatacagcc aagtttggta gagattcaga
     1921 tctggttgct ggatcatgtg tgcaaatgca gcgacttcct cagtcatcgt atgaggagcc
     1981 tgttggatag gaagctggac ttgatttcct tggtggtcgg taaaaatagc tgagcgaata
     2041 tgctcaatcg tgttgagagt caaggttcca tctgttgtat aaatctcgca aggaagattg
     2101 gaagtgatgt tttttccagc cttgatgtga acttgatagt ctgggtagaa gaggatacca
     2161 tctccattta ggtcaatgct attgtcaagc tgttgagcat ggtaagtcgc gtcattagct
     2221 ttttcaaaaa gacgaacagc agcatagagg ggataaatcc ccaaatccat gagggctcca
     2281 ccagcaaaac ggtctgaaaa gacatttggt gtttgtccag ccaacaagtc aggcatcttg
     2341 gaagagtatt tggcatagtt gaaatctgct cctaacactt gcttatctgc taaaaagttt
     2401 ttgatagtag taaaggcttt ctcgtggtaa ttacgagctg cttcaaagat aaaacagtta
     2461 tttttttcag ctgtttgaat caaatcaaac cattcttgtg gttgagtgac agctggcttt
     2521 tcgagaataa catgtttacc agcagacaag gcagcttttg cctgagcaaa atgtaaggag
     2581 tttggactgg cgatatagac taaatcaaaa gaagatttga agaagacttc taattgatcg
     2641 aatagttgga tattctgata gcgagaagca aaggttgctg cagtttctag ttttctagaa
     2701 tagattgcga ccagttggta ttctccactg gtatgggctg cttctatgaa atgatggctg
     2761 atagcgccag ttccgatgac acctaatttt agcataaata ctccttttcc gattttaaat
     2821 ccttctttca ttataacata gatagacggg actatccaac agagaggaga aaatttcaaa
     2881 taagctatta gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag
     2941 atttaaaaat gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca
     3001 gcccaactaa tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg
     3061 acgattttgg agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat
     3121 ttctatacta gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa
     3181 attcaggttc atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag
     3241 gttaatcaaa acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa
     3301 caaatcgcac cagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta
     3361 gcttttcata gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacaatca
     3421 aatcgatttc taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag
     3481 aaattccata gatataaaac tacataatct ctacagatac ggatgttgga gttgatgtaa
     3541 gatgctttgg cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct
     3601 caaatttgtt atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa
     3661 acgagacatg tattattggc tttgattggt attttagcaa tttctatttg cctattaggc
     3721 ggatttattg cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc
     3781 aaaaaagaga aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg
     3841 caagccgaag tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg
     3901 gagttgataa atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac
     3961 tatacagagc aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa
     4021 atctatgatt tagttgcttt taaggttgaa gagactgaaa agaccagtct aggaaaggtt
     4081 cacttaacag aagatggcca accttttaca cttgaccaac tgttttcaga tgctagtaag
     4141 gctaaggaac agctgataaa agagttgacc tccttcatag aggataaaaa aatagagcaa
     4201 gaccagagtg agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt
     4261 gattacaagg atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag
     4321 atagccttgc cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa
     4381 gatgcggcct tgtaccaatc ttactttgat aagaaatatc aaaaagttgt cgctctaacc
     4441 tttgatgatg gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat
     4501 gatattaaag cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg
     4561 aagaggataa aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc
     4621 tcgcaactct ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact
     4681 aaagtgctgg gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat
     4741 attcgcaata gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag
     4801 agtaaaaatg aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc
     4861 gttttgatgc atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat
     4921 ttgaaaaatc aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa
     4981 gctcatgagc tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat
     5041 ttgacagact tattttttac agaagatagt actacttaaa aaatgtttta tgctataatt
     5101 gatgaataaa atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa
     5161 ttccagtatt gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag
     5221 tgttagaagc cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg
     5281 aagaaagtgt tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa
     5341 ctaccaagct ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat
     5401 ctatagaaaa actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa
     5461 aaccgctcag agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg
     5521 aagacctcta tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc
     5581 atttggatgc cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg
     5641 cgccaggtgt gtatcaagat caagtcgtag cttactgtcg tgaaaaggga attttattgg
     5701 aagcttgggg gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg
     5761 cagcaaatca cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat
     5821 ttttaccact tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg
     5881 gaattgaact gagtcatgag gagagagaaa acttaaaaac gattgctgtt caatcgggtg
     5941 ctccacgagt tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta
     6001 atttttgata taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg
     6061 gatagtggga gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa
     6121 acaatgaagt aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc
     6181 taggattgtc ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc
     6241 cgtggacaac ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt
     6301 agtaagaaat actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt
     6361 ctgtgattta ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag
     6421 ggaaagcgct gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc
     6481 tgtttggaaa gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca
     6541 agcaatagaa agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca
     6601 tgagttagct cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat
     6661 ctggttcgaa gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga
     6721 atttcaagcg gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg
     6781 ttggcattca ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt
     6841 ttatgaatac tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt
     6901 acaagcggtc ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt
     6961 agattggttt gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac
     7021 aatgtctaag aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact
     7081 gccccacgct cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt
     7141 atgatcgacg aggcagactc atgtcgcaag taatttatat aaaaaggagt aaacaatgtc
     7201 taagaaattg actttccagg aaatcatcct tactttgcaa caattttgga atgaccaagg
     7261 ttgtatgctt atgcaggctt atgataatga aaaaggtgcg ggaacaatga gtccttacac
     7321 tttccttcgt gctatcggac ctgagccatg gaatgcagct tatgtagagc catcacgtcg
     7381 tcctgctgac ggtcgttatg gggaaaaccc taaccgtctc taccaacacc accaattcca
     7441 ggtggtcatg aagccttctc catcaaatat ccaagaactt taccttgaat ctttggaaaa
     7501 attgggaatc aatcctttgg agcacgatat tcgttttgtt gaggacaact gggaaaaccc
     7561 atcaactggt tcagctggtc ttggttggga agtttggctt gacggaatgg aaatcactca
     7621 gttcacttat ttccaacaag tcggtggatt ggcaactggc cctgtgactg cggaagttac
     7681 ctatggtttg gagcgcttgg cttcttacat tcaagaagta gactctgtct atgatatcga
     7741 gtgggctgat ggtgtaaaat acggagaaat ctttatccag cctgagtatg agcactcaaa
     7801 atattcattt gaaatttcgg accaagaaat gttgcttgaa aactttgata agtttgaaaa
     7861 agaagctggt cgtgcattag aagaaggctt ggtacaccct gcctatgact atgttctcaa
     7921 atgttcacat acctttaatc tgcttgacgc gcgtggtgcc gtatctgtaa cagagcgtgc
     7981 aggctatatc gctcgtatcc gtaacttggc ccgtgtcgta gccaaaacct ttgtcgcaga
     8041 acgcaaacgc ctaggctacc cacttttgga tgaagaaaca agagctaaac tcctagcaga
     8101 agacgcagaa taaagagagt gacaaattac gaaaatgggc gaacagagtg agccctgagc
     8161 cagttgccgc agtgatgaag gtatccttag tgaaactaag gatactaggc aaaattggag
     8221 acttttggct ccaattttag caatgaaaca acgaagttgg ttgcttgcgt gccaatcaca
     8281 taaggcaaac tggaaaataa aaagatactt ttcggagaaa aaacatgaca aaaaacttat
     8341 tagtagaact cggtcttgaa gaattaccag cctatgttgt cacaccaagt gaaaaacaac
     8401 taggcgaaaa aatggcagcc ttcctcaagg aaaaccgcct gtcttttgaa gccattcaaa
     8461 ccttctcaac accacgtcgt ttggctgttc gtgtgactgg tttatcagac aaacagtctg
     8521 atttgacaga agatttcaag ggaccagcaa agaaaattgc cttggatagt gatggaaact
     8581 tcaccaaagc agctcaagga tttgtccgtg ggaaaggttt gactgttgaa gatatcgaat
     8641 tccgtgaaat taagggtgaa gaatatgtct atgtcactaa ggaagaagtt ggccaatcag
     8701 ttgaagccat tgttcctggt gttgtagatg tcttgaagtc attgactttc cctgtcagca
     8761 tgcactgggc tggaaatagc tttgaataca tccgccctgt tcacacttta actgttctct
     8821 tggatgagca agagtttgac ttggatttcc ttgatatcaa gggaagtcgt gtgagccgtg
     8881 gccatcgttt cttggggaaa gaaaccaaaa ttcagtcagc attgagctat gaagaagacc
     8941 ttcgtaagca gtttgtaatc gcagatccat gtgaacgtga gcaaatgatt gttgaccaaa
     9001 tcaaggaaat tgaggcaaaa catggtgtac gtatcgaaat tgatgcggat ttgctgaatg
     9061 aagtcttgaa tttggttgaa tacccaactg ccttcatggg aagttttgat gctaaatacc
     9121 ttgaagttcc agaagaagtc ttggtgactt ctatgaagga acaccagcgt tactttgttg
     9181 ttcgtgatca agatggaaaa ctcttgccaa acttcatttc tgttcgtaac ggaaacgcag
     9241 agcgtttgaa aaatgtcatc aaaggaaatg aaaaagtctt agtagcccgc ttggaagacg
     9301 gagaattctt ctggcgtgaa gaccaaaaat tggtgatttc agatcttgtt gaaaaattaa
     9361 acaatgtcac cttccatgag aagattggtt cccttcgtga acacatgatt cgtacgggtc
     9421 aaatcactgt acttttggca gaaaaagctg gtttgtcagt ggatgaaaca gttgaccttg
     9481 ctcgtgcagc agccatttac aagtttgact tgttgacagg tatggttggt gaatttgacg
     9541 aactccaagg aattatgggt gaaaaataca cccttcttgc tggtgaaact ccagcggtgg
     9601 cagctgctat tcgtgaacac tacatgccta catcagctga aggagaactt ccagagagca
     9661 aggtcggcgc agttctagcc attgcagaca aattggatac gattttgagt ttcttctcag
     9721 taggattgat tccatcaggt tctaatgacc cttatgccct tcgtcgtgca actcaaggtg
     9781 tggttcgtat cttggatgcc tttggttggc acattgctat ggatgagctg attgatagcc
     9841 tttatgcatt gaaatttgac agtttgactt atgaaaataa agcagaggtt atggacttta
     9901 tcaaggctcg tgttgataag atgatgggct ctactccaaa agatatcaag gaagcagttc
     9961 ttgcaggttc aaactttgtt gtggcagata tgttggaagc agcaagtgct ctcgtagaag
    10021 taagcaagga agaagatttt aaaccatctg ttgaatcact ttctcgtgcc tttaacctgg
    10081 ctgagaaggc agaaggggtt gctacagttg attcagcact atttgagaat gaccaagaaa
    10141 aagctttggc agaagcagta gaaacactcg ttttatcagg acctgcaagt cagcaattga
    10201 aacaactctt tgcgcttagc ccagtcattg atgctttctt tgaaaatact atggtaatgg
    10261 ctgaagatca ggctgtccgt caaaatcgtt tggcaatctt gtcacaacta accaagaaag
    10321 cagctaagtt tgcttgtttt aaccaaatta acactaaata aaatttgata aacggacttt
    10381 atcttattac aaaggagaag aaatggatcc gaaaaaaatt gctcgtatca atgagcttgc
    10441 taaaaagaaa aaaacagaag gcttaacacc agaagaaaaa gtggaacaag ccaaactacg
    10501 tgaggagtac atcgaaggtt atcgccgcgc tgttcgtcac cacattgaag gaatcaaaat
    10561 tgtggacgaa gaaggaaacg atgttacacc agaaaaacta cgccaagtac aacgtgaaaa
    10621 aggattacat ggccgtagtc ttgatgatcc aaattcataa taatactctt cgaaaatcaa
    10681 attcaaacca cgtcagcttc accttgccgt acttaagtac agcctgcggc tagcttccta
    10741 gtttgctctt tgattttcat tgagtatatg tattctttct tttaacaaag atagatgaaa
    10801 cgataacaaa gagactagca gtttgtgttt gctagtcttt tttcgctaaa aaaggaacca
    10861 taatggttcc taaaaactat cattagtaac ttgcaccggc tgtagcgtct gcgtcaccac
    10921 cgtggcctcc agcatcccct gaatcagaag cgccagaagt agcatcggcg tctccatgac
    10981 ctccggcagc aggagcaaat ggtccgctac cacccaccaa acgttgacca gtctctttta
    11041 ggtaccagtc aagccatggt tggaagttaa agacgatttc attgatacca gcgtatgatc
    11101 catcaggata gtacattgct tggtagttgt gagtgttgat aacacctgca ggagaacctg
    11161 gaacgatcgt acggacgtat tcttggtttc cgttgcgaag tgttccgata acccactcta
    11221 cgttcttcat acgtgctggt ggaagagaac catgaacagt cgacatacgg ctacctgatt
    11281 gaggtggtac acgtttagcg aacatagtgt ctggatcttg gtgagcgttg ttgtagtaga
    11341 ggaattggtt gttgtcgtca gcgtatgtca attcaaatgg catagctttc aagaacatat
    11401 caatttggtt aactgttagg ataccgtggt ccaatttgac ataggtatca ccagaaacag
    11461 caccagtgaa tgctgcaact ttttctaccc attctggatc gtcagggtca acttctgtga
    11521 tggttgtagc gattggtttt ccacaatcca agtcttctga ttcgattggt tttggttttt
    11581 tcaatttcga aacgactcct acgtatttaa caaagttatc taagcaagtt tcaaggaatt
    11641 taacagtgcc ttcgttggtg atatttccgt tgttatcaaa agcttcctta gctttaccaa
    11701 gaaggaattc gttacctgga agcgtgtagg cattaacacc tggagcatca aggattttac
    11761 gaaggtgaac ttgagcacgt gatgttcctt ggtcatagta tgatgcaccc acaatcataa
    11821 caggcttgtt ttcaaatgga tgaacttcgt atgaaagcca ttcaagtaca gatttgagtg
    11881 aagctgagat agtgtggtta tgctcaggag tagcaatgat aacaccatct gcacgagtaa
    11941 ttttgttata taaataacgt aattggaaac tttcatccca tttttcatct tggttaaaca
    12001 ttggaacttc gtcaatttca agaacttcta attcaaattt gagtttgaag tagcgacgga
    12061 taaattccaa gagcttacgg ttatatgatt gatcgtagtt tgatccaaca agtccaacaa
    12121 atttcattct ttttggtctc ctatcttaca aattttccca gtcaaagtct tcagcatctt
    12181 tgcgaagtaa ttcttgtgca ttacgtaatt tttctgtgat ttttacaaag atacggaagt
    12241 catcaaagat ggcatccaat ttcttgataa catcaaggtc aaccaagtcg ccacttgggt
    12301 taaatgcttg aagagagtgt gagagcaaga attcatctgg aagaacattt gccttgattt
    12361 caggagcatt caagatttga cgaagttgca attgggcacg agatgaacca agcgtaccgt
    12421 aagaagcacc tgtaatcatg attggtttgt tcaaaagtgg gtaaatacca taagataacc
    12481 aagcaagagc gctcatcaaa acagctggaa tagagtgatc atactcagga gtaccgataa
    12541 taacgccatc tgcctcttcg attttagcag caatttccaa tatttcagca ggtacttgct
    12601 tgtcagctgg tttgttgaag acaggaatgg ccttgatttc aacaagttca atttcagctt
    12661 tgtcagtaaa gtgtttttgc atgtattgaa gcaattgacg gtttgtagaa cgttttgaat
    12721 ttgttccaac aatagcaata agttttaaca tgagatttcc tttctctttt tacataatac
    12781 aattttaaaa ttccattgaa acagttgtct ctatagagta ggaattcctg aagaacagct
    12841 taggtggcct tctttatcga tgaggatgac ttcgatgccc tccaaacttt cgacttgcca
    12901 gaggatagaa gcaggtcttt ctccaaagag tcgagtcgtc cagatttcgc catcgactga
    12961 tttatcagag atgattgtta gactcgctag ttccgtttca acaggatatc ctgtttgact
    13021 gtcaaaaatg tgatggtaat cttgtccatc gacggtcagg tgacgttcat aaatgcctga
    13081 agtcacgaca gatttattga caacagggat ggtcattaaa tgatttcccc taggattggc
    13141 tgggtcttga atcccgattt gccatgggtt atcccctctt gcctgatttt ttccaatggt
    13201 caggatattc cctcccagat tgatcaaggc agaagtcacc ccctctttcc taagaaattg
    13261 ggcaacctta tccgcactgt atcctttggc taaacaacct agatcgatct tcattccttt
    13321 ctgttttaaa aacacagtag aagtagaaga atctaactcg ataccatgag gattgattag
    13381 aggcagcacc gattcaattt cttgaggctg ggcgaccttg gcatctgaaa aaccgatacg
    13441 ccaggtttga attaagggac caatgctgat attgaggtgg ctagagagcg ctaggctatg
    13501 ctctaaccca agtgaaatca gctcaaacag gtctggatga accgtgacgg gggctattcc
    13561 tgcttgataa ttgatttcca tcaactcaga ttcttgacta ttggcgttga agcggtattc
    13621 aagttctttg agcaagtcaa aggatttttg gagaaagata tcggcttgct catccactaa
    13681 tgaaatagtg atagtagtcc ccattagccg ttcagaatgt gaacgaagag tcaagctacc
    13741 aactcctttc tcttatagaa aataagttgt aatatcaaat aatcatctaa attgaagccc
    13801 ttacatttca ttttcatgtt attataatac cataaagtta gaattttcac aaacaaaatt
    13861 tggaaaaagt caagaaatat gctcataaaa ttcatcaggc ttgaaaacag gataaatggg
    13921 gaattatttt tgataaaaaa tgctgaaata atagtacccc ccttgtaaac gctaacggta
    13981 aatggtatac tagtaaggta aatttagaat gaaggcagga aatttttatg agtaaaatcg
    14041 ttgtagtcgg tgctaaccac gctggtacag catgtatcaa taccatgttg gataattttg
    14101 gaaatgagaa cgaaattgtt gtatttgacc aaaactctaa catctctttc ctaggatgtg
    14161 gaatggctct ttggattggt gaacaaattg acggtgctga aggcttgttc tattctgata
    14221 aagaaaaatt ggaagctaaa ggtgctaaag tttacatgaa ctcacctgtt ctttcaatcg
    14281 actatgataa caaagtagtt acagcggaag ttgaaggaaa agagcacaaa gaatcatacg
    14341 aaaaattgat tttcgctaca ggttctacac caatcttgcc accaatcgaa ggtgttgaaa
    14401 ttgttaaagg aaaccgcgaa tttaaagcaa ctcttgaaaa cgtacaattc gtgaaattgt
    14461 accaaaatgc tgaagaagtt atcaataaac tttctgacaa gagccaacac ctcgaccgta
    14521 tcgccgttgt tggtggtggt tacatcggtg ttgaacttgc tgaagccttt gaacgtcttg
    14581 gaaaagaagt tgtccttgtt gatatcgttg atactgtctt gaacggttac tatgacaaag
    14641 acttcacaca aatgatggcg aagaacttgg aagatcacaa catccgcttg gctctaggtc
    14701 aaactgttaa agcaatcgaa ggtgacggta aagttgaacg cttgattact gacaaagaaa
    14761 gctttgacgt ggatatggtt atccttgcag ttggtttccg tccaaacaca gcccttgcag
    14821 gtggtaagat cgaactcttc cgcaacggtg ccttccttgt agacaagaaa caagaaacat
    14881 ctatcccaga cgtttacgct gttggtgact gtgcgactgt ttatgacaat gctcgtaaag
    14941 atacaagcta tatcgctctt gcttcaaatg ctgttcgcac tggtatcgtt ggtgcctaca
    15001 atgcttgtgg acatgaattg gaaggaatcg gtgttcaagg ttcaaatggt atctcaatct
    15061 acggtcttca catggtttca actggtttga ctcttgaaaa agcgaaagct gctggttaca
    15121 acgcaactga aacaggcttt aacgatcttc aaaaaccaga attcatgaaa catgacaacc
    15181 atgaagtagc aattaagatt gtctttgaca aagatagccg tgaaattctt ggtgcccaaa
    15241 tggtttccca tgatattgca attagcatgg gaatccacat gttctcactt gctatccaag
    15301 agcatgtgac aattgataaa ttggcattga cagacctctt cttcttgcca cacttcaaca
    15361 aaccatacaa ctacatcaca atggctgccc ttacggctga aaaataaaaa tgaatgagct
    15421 atctggcctt aagttaaggt cagatagttt ttagctaatc tgtccccata caattatagt
    15481 ttttttatct tgtgcttcat tctgttctga cttaaaatga aaaggtagct accaatacaa
    15541 atgatgagga taaaacaaat gactgaaaat cgttatgaac taaataaaaa cttggcacag
    15601 atgctcaagg gtggtgttat tatggatgtg cagaatcctg aacaggctcg tatcgcagaa
    15661 gctgctggtg cggcagctgt gatggccttg gaacgaattc cggctgatat tcgtgcagct
    15721 ggaggagttt cccgcatgag cgacccaaag atgattaagg aaatccaaga agcggttagt
    15781 attccagtaa tggctaaggt cagaatcggg cattttgttg aagctcagat tttagaggct
    15841 attgaaattg attatatcga cgagagtgaa gttctatctc cagctgatga ccgtttccat
    15901 gtggacaaga aagaattcca agttcctttt gtctgtggtg ctaaggattt gggtgaagcc
    15961 ttgcgtcgta tcgctgaagg tgcttccatg attcgtacca aaggagaacc agggacaggg
    16021 gatatcgtcc aagctgttcg tcatatgcgt atgatgaatc aggaaattcg ccgcattcaa
    16081 aacttacgtg aggacgagct ttatgttgct gccaaggatt tgcaagtccc tgtagaattg
    16141 gtccaatatg ttcatgaaca tggaaaattg ccagttgtaa atttcgctgc tggaggtgtt
    16201 gcaacgccag cagatgctgc gttaatgatg caactagggg cagagggggt ctttgtcggt
    16261 tcaggtattt tcaagtcagg agatcctgtt aaacgagcga gtgccattgt taaggctgtg
    16321 actaacttcc gtaatcctca aatcctagct caaatctctg aagatttagg agaagccatg
    16381 gttggtatta atgaaaatga aatccaaatt ctcatggctg aacgaggaaa atagatgaaa
    16441 atcggaatat tggccttgca aggggccttt gcagaacatg caaaagtgct agatcaatta
    16501 ggtgtcgaga gtgtagaact cagaaatcta gatgattttc agcaagatca gagtgacttg
    16561 tcgggtttga ttttgcctgg tggtgagtct acaaccatgg gcaagctctt acgtgaccag
    16621 aacatgctac ttcccatccg agaagccatt ctatctggct taccagtgtt tgggacctgt
    16681 gcgggcttaa ttttgctggc taaggaaatc acttctcaga aagagagtca tctaggaact
    16741 atggatatgg tggtcgagcg taatgcttat gggcgccaat taggaagttt ctacacggaa
    16801 gcagaatgta agggagttgg caagattcca atgaccttta tccgtggtcc aattatcagc
    16861 agtgttggag aagatgtaga aattctagca acagttgata atcaaatcgt tgcagcccaa
    16921 gaaaaaaata tgttggtaac ttcttttcat ccagaattga cagatgatgc tcacttacac
    16981 cagtacttta tcgaaatgtg taaagaaaaa agacagtaaa aaagctcaaa aaatcacttc
    17041 ctgtgctata ctgtaattga aattttttta gtttttgcgt tagaactgtt tcctcagtcc
    17101 tagcgccttt tctttttgat aagtctgctt ggtggagagt agtttgtaaa cgattctgag
    17161 aatcttatga gcacaagcaa tgacggcttt catcttgctt cctctttggg aaattcgatt
    17221 gtaaaactct aagcaggcag agcctgctta gagttttaca tatgctacta tctttgttat
    17281 agctaactta aattctcatt tattaagtat acctaagttt tatgtttaaa ttttgtatag
    17341 aatagttgta tcacttaaca aagctatgtt tacgctttca atcaagtctc atttatgata
    17401 ctattatggt aatagaaaaa attcttagtt cgctaaagac ctttattcga gatccagagg
    17461 aaatagaaat tttatccatt aaaaatacgt ttcataagtt acttacttga tattaataga
    17521 attccaatat tgtataatta aatcaaagat gacactggaa tcaggaggat ttattatggt
    17581 taataatgta gctgttaaag tctcaaacct ttcaaaagaa tttttgttag ggcaagacaa
    17641 aactgtctct attttgaaag atatttcctt atctgtcaat tatggggaat ttgtatcaat
    17701 acttggtgtc agtggttctg gaaagtctac tttgctaagt tgcttatcaa gtttatctga
    17761 accaacaagt ggcgaagttg ttatcaatgg tgtaaatcca tataccttaa aagaagggaa
    17821 gcttgctaaa tttagaagac aagatattgc aataattttt caaaactata atctggtacc
    17881 tgctctacct gtactagaaa atgttacact tcctctgaga ctatcaggaa agagtgttga
    17941 tagcaataaa gtaaaaaaaa tgttggatag tttgaatttt aaagcagaac tatcatcatt
    18001 agttgctacc ttatcaggtg gagaacagca aaaagtggct attactcgtg caataatagc
    18061 tgatagtaaa attatttttg ctgatgagcc aacaggagct ctggacagcg tctcaagaaa
    18121 acttatattt gaaacacttc gtaatttagc gagtcaagga aaatgtgttc ttatggtcac
    18181 tcatgatatt gagttggctt caaaaactga cagagcactc attttaaaag acggaaaaat
    18241 atctcgacaa attattaaac cttcagctga tgagctctac caagcacttg aaagtagtaa
    18301 agattaattt gaggaggatt tattatgcta aaattaatca tttaccaatt tcagtactca
    18361 aaaagacaat ggttaggaac aataccatta ctatttgtat ctagcctgat tgttggaaca
    18421 tctttatttg gtattgctag ttcaatcaag actgctaata ttaacgcttc acaacttttt
    18481 caaatgctaa taatttttgg cgggactact ctatttttcc ttatttcaaa taatataaga
    18541 ctgctaatag atatctttaa aaaggattac caattatgga ctatcttagg cgcaagcaga
    18601 actcagctat ctttattagt atctggacag ttttatttaa tggcagtgat tgttagtagt
    18661 attggtacaa tactttcatt tatcatggca gatagttatt acaaattttt acaaaattta
    18721 ttaggaagag atgagttacc tgatttagtt attacagcca acattcaatc aattttattg
    18781 agtattttta tagtcccaac aattgtcggg ataggggctt acttttattc aagtcgaata
    18841 cttaaaatat catcaatatt aaaaccaaaa aagaaaaaaa gaaaagttac agtaactgga
    18901 tttgttaaca tctctgttcg tttattccta tggctactat gtataggttc tattgtttca
    18961 gcaggtttta tcagaaacaa agaaataatt gaaaaacagt caagcataat attattttta
    19021 ttaattattc acatccttat tattcaatca ctatctccat caattcaaat gtttctaata
    19081 aaatttttaa tgaggatatt tccaactgaa aattatgtaa ttaatacagg cttttggaat
    19141 ctactatcca atcctagcta tttgaaaagt atacaaactt caatgagcat gggagtaact
    19201 ctcatttctg ggtttattct ttacacccaa aatatgtatt cattcatgaa tacagcaaac
    19261 ggagtaaacg aagcaagagc ttcctttatt gcttatatgt ctgcaccaat tattctgatt
    19321 attactagtt ctatttctct tacaatttta tcttctaata aagatattga ggacattaaa
    19381 cagttaaaga cactgggagt gtcaagatta caacttttta aaatacgtat aggcgaggca
    19441 ataatacatt cggtgttaat tttattagtg tcagtaattt tcaatttaat tattttaatt
    19501 ttagttagca ttattggcca atttttaggt cgtagtttag tagatatatc aggtttctgg
    19561 caaccgagtc ttatagttat ttctttgtta gttatttttt atagtattac aaagggattt
    19621 tatttatttc aagatagata aattggaata gttactgaac caaaaagaa
//
LOCUS       DAVLBN010000040        18704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLBN010000040 DAVLBN010000000
VERSION     DAVLBN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.040"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(207..1013)
                     /gene="yidA"
                     /locus_tag="VXC24_001425"
     CDS             complement(207..1013)
                     /gene="yidA"
                     /locus_tag="VXC24_001425"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0493527.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1026..2330)
                     /locus_tag="VXC24_001426"
     CDS             complement(1026..2330)
                     /locus_tag="VXC24_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0493528.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2402..2779
                     /locus_tag="VXC24_001427"
     CDS             2402..2779
                     /locus_tag="VXC24_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0493529.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            2869..3201
                     /locus_tag="VXC24_001428"
     CDS             2869..3201
                     /locus_tag="VXC24_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0493530.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            3213..4784
                     /gene="ffh"
                     /locus_tag="VXC24_001429"
     CDS             3213..4784
                     /gene="ffh"
                     /locus_tag="VXC24_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0493531.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(4979..6262)
                     /locus_tag="VXC24_001430"
     CDS             complement(4979..6262)
                     /locus_tag="VXC24_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0493532.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6516..7229)
                     /gene="rsmG"
                     /locus_tag="VXC24_001431"
     CDS             complement(6516..7229)
                     /gene="rsmG"
                     /locus_tag="VXC24_001431"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0493533.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7323..7883
                     /locus_tag="VXC24_001432"
     CDS             7323..7883
                     /locus_tag="VXC24_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0493534.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7885..8784
                     /gene="htpX"
                     /locus_tag="VXC24_001433"
     CDS             7885..8784
                     /gene="htpX"
                     /locus_tag="VXC24_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0493535.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(8933..10492)
                     /locus_tag="VXC24_001434"
     CDS             complement(8933..10492)
                     /locus_tag="VXC24_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0493536.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10731..11048)
                     /locus_tag="VXC24_001435"
     CDS             complement(10731..11048)
                     /locus_tag="VXC24_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0493537.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            11218..11760
                     /locus_tag="VXC24_001436"
     CDS             11218..11760
                     /locus_tag="VXC24_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0493538.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11760..12389
                     /gene="nth"
                     /locus_tag="VXC24_001437"
     CDS             11760..12389
                     /gene="nth"
                     /locus_tag="VXC24_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0493539.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12600..13121
                     /gene="pyrR"
                     /locus_tag="VXC24_001438"
     CDS             12600..13121
                     /gene="pyrR"
                     /locus_tag="VXC24_001438"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0493540.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13140..14063
                     /locus_tag="VXC24_001439"
     CDS             13140..14063
                     /locus_tag="VXC24_001439"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0493541.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14113..15192
                     /gene="carA"
                     /locus_tag="VXC24_001440"
     CDS             14113..15192
                     /gene="carA"
                     /locus_tag="VXC24_001440"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0493542.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15505..18681
                     /gene="carB"
                     /locus_tag="VXC24_001441"
     CDS             15505..18681
                     /gene="carB"
                     /locus_tag="VXC24_001441"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0493543.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5442 a         3614 c         4193 g         5455 t
ORIGIN      
        1 aaaagagatt ataaagagat aacatataga aatagagagt gatttattac aattcagtac
       61 cacaaattaa gaaagcaatg cctatttttt gtactctcaa gatttaagta actgtacaac
      121 tgcaattaaa tttattaatt tactctcatt gtgatatatt catacaaaaa ccgctcagct
      181 gagcggtttt agtctattct ttccttttac agtacccatg ttcggatggc gtgggcaacg
      241 ccggattcgt catttgtttt agtgatgtat ttggcgattt ttttgatttc tggatttcca
      301 ttttccatga caacggggtt tccaacgact tccagcatgg cacggtcatt ttcttcgtca
      361 ccgattgcca tggtttcatc tttggtcaat ccgagttttt cagccaagtg agtaatggct
      421 gaacccttgt ctacattctt tgtaaggagt tcgaggtaga aaggagcaga tttgttgatg
      481 gagtagcgct cgtaaaattc tgctggaatt ttttcaatcg tagcatcgag gatttctggt
      541 tcatcgatga acatacattt gacaatttcc ttgtcagcca tttcttcagg tgtacggtag
      601 aagataggca tgctgacgag ggttgattcg tgcacagtgt attttccgat attgcgattg
      661 gcagtataga taccgtcctt ggtaatggcg tgcatgtgga caccgagctt gcggctgaga
      721 aattccatat ctagataatc ctcataagtc aaggattcgc tgataatctc atgtcctgta
      781 gcagtttctt ggacaagggc accgttgaag gttaccacat agtccccctc gtctctcaac
      841 tgcaagtcgt ctagaagttt ggcaacgcct gcgatagggc ggccagttgc aatcacgact
      901 ttgacaccag cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt
      961 tggctgttga ctagggttcc gtcaatatcg acggcgatta gtttaatact cataaatttc
     1021 ctcttttagt ttttatttgg ggtaaaatga tcgttctcaa tcaagtgtaa aaattgctgg
     1081 gtgatgcttg cgaagatgct gttttggtct aacatttctt tcgggaaata aaagcgatta
     1141 tctccgtggc gacttccagc aagggattgg acgatagggg acaggctaga gagttctgcc
     1201 agttctccat ttttttgtaa aatctcaatc tgtgtccttg gattttcaga ttcgggacgg
     1261 taaatatcat aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag
     1321 ccgatgtcct caaccaattt tctcatgcta gcgagttggt cttggtcttc ttgtgaaaag
     1381 gtaatggatt taaagacctt gcggttgaca aagcgatgcg ataaatctgc aagaatcttg
     1441 tcaggactgg tcatccagag ttggaagtag gtattcatca caccatcatc cagagccaga
     1501 tagtcagtca aggtcacatt tttttcgaag aaaggcagga ggtgtggaga agttcgggca
     1561 aagaaatcct tgtcctcagg atagagttcc ttggcgcgtt tgagaagatt ctgtaggaga
     1621 acttccatgg cgcgtgttgc ggggtggaaa taaacctgca tgtacatctg gtagcgactg
     1681 aggacgtagt cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata
     1741 ggacgaatga ctcggaggat tcgagtcagg tcaaattccc cataggatgc tcctgtaaaa
     1801 taggagtcgc gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagctgc
     1861 acgacctgct tgttaggata ggtatggtct atgacactgg caactttctc tggaaaatcg
     1921 ggcgctactt gtagcaggac ttggtgaatc tctgtctcag gattttgaat aatctcctga
     1981 gtaatggctt catggtctgt atcaaagaga ttttcaaaag tatgggagta ggcaccatgc
     2041 ccaaggtcgt gtaggagagc agcggtcatg gtcaagagag actcggcagg attccattcc
     2101 tcaggatatt tttcttcgaa aatctctgtg atgcgtcgtg caatttcata gactcctaga
     2161 cagtgagaga agcgactgtg ttctccaccg tggaaggtat aactggaagt tcccagttgt
     2221 ttgatccggc gcaaacgctg aaattctttt gtattaatca agtcatagat gatttgatta
     2281 ttgacatgga tgtagttgtg aacagggtca cggaatactt tttcgttcat atgaccatta
     2341 tagcaaaatc ctgctctttt tggtaaaata gtaggacaag agacaagaaa gagggcctga
     2401 tgtgaagatt cggatgcgaa atacaattca gtttgatgag cagttggaag tgattgacca
     2461 gctttatgat gtggaagtgc atgaaaaagg agattatagc tacctgcttt tctataatga
     2521 ggaaaaggaa aaagtagtga ttaaatttca tggtcaagaa cttatgatga gccgattttc
     2581 caatcccaag accattatgc gctttttaaa ggatagtgat agtttggcct atattcctac
     2641 ccctatgggc atgcaggaat ttatcattca aacgagccgt tatcaagtag atgggcaaaa
     2701 gattgagcta gcttatcaac tacaaaatca agaggggcat ccctttgcca gctatcaatt
     2761 ggaaattact tggggctagg atctcgtttt tctcaaatct actttctatc ttcaaggatt
     2821 ggctccctag tgtggtagat taggctattt tttggtataa taaaagttat ggaaatcgaa
     2881 aaaaccaatc gtatgaatgc gctctttgaa ttttatgcgg cgcttttgac agataagcaa
     2941 atgaattata tcgagcttta ctacgctgat gattacagtc ttgctgagat agctgaggag
     3001 tttggtgtta gtcgtcaggc tgtctatgac aatatcaagc gaacagaaaa gattctggaa
     3061 gattatgaga tgaaattgca catgtactcg gactacattg tccgtagtca gatttttgac
     3121 caaatcttgg agcgctatcc caaggatgat tttctgcagg agcagataga aattttaaca
     3181 agcattgata atagagaata agaggaagaa aaatggcatt tgaaagttta acagaacgtt
     3241 tgcagaacgt ctttaaaaat ctacgtaaaa aaggaaaaat ctctgaatct gatgtccaag
     3301 aggcaaccaa agaaattcgc ttggccttgc tcgaggccga cgttgccttg cctgttgtaa
     3361 aggactttat caagaaagtt cgtgagcgtg cagtcgggca tgaggtcatt gatacactta
     3421 atcctgcgca acagattatt aaaatcgttg atgaggaact gacagccgtt ttaggttctg
     3481 atacggcaga aattatcaag tcacctaaga ttccaaccat catcatgatg gttggtttac
     3541 aaggggctgg taaaacaacc tttgctggta aattggccaa caaactcaag aaagaagaaa
     3601 atgctcgtcc tttgatgatt gcggcggata tttatcgtcc agctgccatt gaccagctta
     3661 agaccttggg acaacagatt gatgtgcctg tctttgcact tggaacagaa gtaccagctg
     3721 ttgagattgt acgtcaaggt ttggagcaag cccaaactaa tcataacgac tatgtcttga
     3781 ttgatactgc gggtcgtttg cagattgatg agctcctcat gaatgagctt cgtgatgtga
     3841 aagcattggc tcaaccaaat gaaatcttgc ttgtcgttga tgctatgatt ggtcaggaag
     3901 cagccaatgt tgcgcgtgag tttaatgctc agttggaagt gactggggtc atccttacca
     3961 agattgatgg cgatactcgt ggtggtgctg ctctgtctgt tcgtcacatt actggaaaac
     4021 caatcaagtt cactggtaca ggtgaaaaga ttacggacat tgaaaccttc cacccagacc
     4081 gcatgtctag ccgtatcctt ggtatggggg atatgctcac tttgattgag aaagcttctc
     4141 aggaatacga tgaacaaaaa gcccttgaaa tggctgagaa gatgcgcgaa aacacctttg
     4201 attttaatga tttcatcgat caattagatc aggtgcaaaa tatggggccg atggaagact
     4261 tgctcaagat gattccaggt atggccaaca atccagccct tcaaaacatg aaggtggatg
     4321 aacgccagat tgctcgtaaa cgtgccattg tgtcttcgat gacacctgaa gagcgtgaaa
     4381 acccagattt gttaaatcca agccgtcgcc gtcgtattgc tgctggttct ggaaatacat
     4441 tcgtcgaagt caataaattc atcaaggact ttaaccaggc taaacagctc atgcagggtg
     4501 ttatgtctgg ggatatgaat aaaatgatga agcaaatggg gattaatcca aataaccttc
     4561 ctaaaaatat gccaaatatg ggaggaatgg atatgtctgc ccttgaagga atgatgggac
     4621 aaggcggtat gcctgactta tcagctctcg gaggagcagg aatgccagat atgagccaga
     4681 tgtttggtgg cggtttgaaa ggtaaaattg gtgaatttgc catgaaacag tccatgaaac
     4741 gtatggctaa caaaatgaag aaagcgaaga agaaacgcaa gtaagacaag agattgatgc
     4801 aaatctcatt tgatgagaaa ataaagtaaa aatttctatg ataaaacgta cagtatcaag
     4861 gttttagaat atctgatatt atacgttttt tgattttaat aattttgtta agacactttt
     4921 attatagtat acgaaaaatc cactcagctg tctgagtgga ttaggtgtat ttagactctt
     4981 agtctttatt ttcgtatggc aagatcaagt tcaagatgat tcctgtcatg gctgaaaggg
     5041 cagtacctga aagtgtaact ggaccaagtt taaggatagc tcctccaagt ccaagaacca
     5101 acatagcact tgcgatgatg aggtttcgca tttgagcgaa atcaacacgt tctttaatca
     5161 agactttcaa accattgctg gcgataaccc catagagaag gattgacata ccaccaagta
     5221 cagcgtttgg aatagttgaa atcaaggcag tgaatttacc aaggaagctg agggcaatcg
     5281 cgatgaaggc agcgttacgg ataactgaga cagaagcgat acgagtcata ccgataaccc
     5341 ctgtattttc tccgtaagtt gtattggctg gtccaccaag gaaggcagaa acagaagttg
     5401 cgataccgtc accaataaga gtacggtgaa gacctggttc ttttaagaat tgacggccac
     5461 agatttgacc caaaacagta tggtctccga tatgttcaga aattgttacg atagcgattg
     5521 gcaagatagc gatggcttct ggaccaaagt aaagattgta ctctttaaag gcaccacttg
     5581 tgctaaatgg caagtagaaa ccaggaattt caaaccagtt agcttctagg acaggcgtaa
     5641 agtcaaccaa accaagagtt agtgcgaaga ggtaaccacc gataatggca aagaggaatg
     5701 gaatgattcg taggaagcct tttccttttg tattgataaa ggcagcaatt aggaaagtaa
     5761 caacggctac cagagcattt ttccaatttc cgtctgctac aagacctgca ttggtaacag
     5821 ctgaacctgc aagtccaaga ccgataacga tgatcatagg accgataatg attggtggca
     5881 agagtttatc aatccatttt gttcctacaa atcggatgct ggtagcaaca aggacataga
     5941 ccaaaccagt caagataacc cctgtttgag cagcagatac atcccccccc atttctttca
     6001 tagccagtga catagctgtg ataaaggcga atgaagaacc tagataaact ggaactttaa
     6061 aaccagtagc aagcatgtag atgagtgttc caacacctga agcaaaaagg gcaacagata
     6121 caggcattcc caaaatcaat ggtaccaaga tggtcgcacc aaacatggcg aaaacgtgtt
     6181 ggaaactaag gagaattcct tttccagccg aaggacgttg gtcaacgtct agtaacaaat
     6241 caacagttga ttcttgtttc atataaacct cacttttggg catcaaaaaa gagcccatta
     6301 ttttacagca ataggccctc agagtaagac ttctttaaaa tttagatttt aaagagtttt
     6361 aaatatttct gcgtcttcgt cacctcacgg gatgacatta aaaacctttg cttaggatag
     6421 tatagcagaa aaaaatgatt ttgtaaatca ttttttcccg agcctagaaa taaaagagcg
     6481 aggctgattt tgtaaacatt tgtttactaa aaaatttaaa gtgggcgttt atttggcata
     6541 ccagccttac gtggatattt atttggtgtt tcttttttct tttctaccac tgtgatatag
     6601 cgcggatctc tattcggtag ggcgtagctg agattgtctt cgaccttact aaaaaggaga
     6661 ttgagggcat tcttagcttc taataattcc tcaggcgcat tgctggcctt gagtgccaat
     6721 agttttccac caaccttaag gtagggaatg gtcaattcag ataggacctg catacgggca
     6781 accgcacgag ctgttacaaa atcatattga gcacggaagt tcttgtcttg ggcaaaatct
     6841 tcggcacgtc cgtggtagaa atgaactccg ttcaaatcca gttcttgagc caagagttgt
     6901 aggaagttga tgcgcttatt gagtgaatca ataatggtca catctaactc cggatagaga
     6961 attttcattg gtagactagg aaatcctgcc ccagccccga tatcaagaag tttgatagtt
     7021 tcattgggaa tcaaaccttg aagaatgggt gcaatcgaat cgtaaaaatg tttgagataa
     7081 acttcttcct tgtccgtaat cgccgtcaaa ttaatcttct cattccactc gaccaagagc
     7141 tcaaaataac gttcaaattg ttctttttgc tggtccgaaa gtggaagatt ctgctcggca
     7201 agcaagttgt aaaatgtttt tggtttcata gttatttcct tctttagtat catcttattt
     7261 taccacaatc atagaaaatt tgatatactg gtactaatct aaaagcagaa aggacttata
     7321 ttatgacttg gattattctt ggagttatcg ctcttattgt tatttttgtg attgttagct
     7381 ataacggttt ggttaaaaat cgtatgcaaa ccaaggaggc ttggagtcag attgatgttc
     7441 agttgaaacg tcgaaatgac ctcttgccga acttgattga gactgtaaaa ggttatgcca
     7501 aatatgaagg ttctaccctt gaaaaggtgg cagaactacg taaccaagtg gcggcagcga
     7561 cttcaccagc agaagctatg aaagccagtg atgccctcac tcgtcaggtt tcaggtattt
     7621 ttgcagttgc agaaagctat ccagatttga aagctagtgc taactttgtt aaattgcaag
     7681 aggagttgac aaacacagaa aataaaattt cttactctcg tcaactctat aacagtgttg
     7741 tcagcaacta caatgtaaaa ttagaaactt tcccgagcaa tattatcgct ggaatgtttg
     7801 gatttaaagc ggcagatttc cttcaaacac ctgaagagga aaagtcggtt cctaaagttg
     7861 attttagcgg tttaggtgac taagatgttg tttgatcaaa ttgcaagcaa taaacgaaaa
     7921 acctggattt tgttgctggt atttttccta ctcttagctc ttgttggtta tgcggttggt
     7981 tatctcttta taagatctgg acttggtggt ttggttatcg cactgattat cggctttatc
     8041 tacgctttgt ctatgatttt tcaatcgaca gagattgtca tgtccatgaa tggagcgcgt
     8101 gaggtggatg agcaaacggc accagacctc taccatgtag tggaagatat ggctctggtc
     8161 gcccagattc ctatgccccg tgttttcatc attgatgatc cagccttaaa tgcctttgcg
     8221 acaggttcta atcctcaaaa tgcggctgtt gctgcgactt caggtctact agctatcatg
     8281 aatcgtgaag aactagaagc tgttatggga catgaagtca gtcatattcg taattatgat
     8341 atccgtattt cgactattgc agttgccctt gctagtgcta tcaccatgct ttctagtatg
     8401 gcaggtcgta tgatgtggtg gggtggagca ggtcgcagac gaagtgatga tgaccgagat
     8461 ggaaatggtc ttgaaatcat tatgctagtg gtttccctac tagctattgt actggcacct
     8521 ctcgctgcaa ccttggttca gctcgctatt tctcgtcaga gggaatttct ggcagatgca
     8581 tctagtgtcg agctgactcg caatccccag ggaatgatta atgccctaga taagttggac
     8641 aatagcaaac ctatgagtcg ccacgtcgat gatgctagca gtgctcttta tatcaatgat
     8701 cccaagaaag gtggggggtt ccaaaaactc ttttataccc acccacctat ctcagaacgg
     8761 attgaacgtt taaaacagat gtaaaatgaa ggctggaaaa aagtctttaa aatctgaaaa
     8821 acgcataata tcaggtgtga aaacttgata ttatgcgttt tactatggga agatttactt
     8881 ctttttctcc taaaattgtg tttttgcccc acctatctgc tatgttgcaa atttataaat
     8941 cttctaaatt aactagcttc aaaccgtgtt ctgtcatgcg atagatgatc gagcagattt
     9001 cttttaagaa acgacggtca tgcgaaacag tgatgagacc gcctggatag gttgcaaaga
     9061 gttttctgat ttggggttga gaagtgggag aaaagtttcg tgtgggttca tccagcagga
     9121 gaaagtttgg tttgcgcagg actaaatcca aaagcaggag ttttccctgt tgtccgccag
     9181 ataaggagcg aatttgatgc tgcatttctg gataactgaa attgagactg gctaggtgag
     9241 attggatttt ctgaagttcc tctttttccc cagttttgct gatataagct attggtgata
     9301 aatccaattg cagttttttg tggtaatctt gtggcataaa accaagggaa atctctcttt
     9361 tatcattcag aagttgcttt aatttggcta acagagttga tttcccaaca ccatttggcc
     9421 cgataatacc gattttttct tgcccacgga cagttagttg tagtttttga accaaaactc
     9481 ggtcgtcaat ggacaaattt tctttttcca gttggactaa gactttagaa gctggtaatg
     9541 gttggatgtc tgaaaagaaa agttggattt gttcctcttc aagtggcttt tgagtcatgg
     9601 actgagctgt cttttcgtag cgtttttctt gtgagaggac agttttcatc tttttagcca
     9661 ataggcgacc ggcagtacta tctttggtag ctcgaagcgc agtttctaca ttttgcttaa
     9721 ctctccgatg tttttccatg gttttatcgt aggctctttg gttgttagca gcttgctgac
     9781 tttgtttggc aaaattagcc tttctctgct cactatagct atcatagtct aaatgctcta
     9841 ctagcgtttc cgcttcttta cggtgtttga ccagtcgcaa gtgaacaata gtgtctgctg
     9901 tttcagaaag aaagtcttca tcatgggaaa tgaaaataac ggtttgcctg gtcttttgaa
     9961 tctggccttt tagccaatca actgtctcaa ggtctaggtc atttgaaggt tcatctaaaa
    10021 atagaatctc aaagggtttg gctaactcat ggataagctg aattttcaaa gcttctcccc
    10081 ctgatagatt gccaatcttt tggtcacttg cgaaacgatt gctatcaaaa tgcaattcct
    10141 ccgccaaacg atagaggata ctgtagtcta aatcaataga atctaaaaag aagtagtcgt
    10201 gtaaagtttt ctttttcagc tcctcgggaa gtttttgagg aatgtaggcc agtgactgat
    10261 agtcagattg gatgtttccc ttgatagtga aatcagacaa agcttccccc attaaaattt
    10321 taagtaaggt tgatttgcca tttccttctt caccaataat agcaaccttt tccccgtctt
    10381 ggatggtcat gcttaggtca gatacaagat ctcgtaaatc tttgttttgt gtgatggtta
    10441 gatgattgat ttttatcata tgatttccct ttctagaatg ttcatagtgc ataacaaaaa
    10501 gctctacttt acctagtaga gcccaaagtc tatgtcaaaa aaactctatt aacatgccag
    10561 aaaaagagca taaaagagca cacaaaaaga gacaaaaaca agatctacta aataaaggtt
    10621 ctttatttga tagacttagt tgttcatgtc tcccttacct ccgagtatta gtatctttat
    10681 attatacctt taaggaaatt ttgtcaacag aaaactggaa attctatgct ctaaaatcca
    10741 aaaacaggtc catagagact tagtacgtgt ttgacatgct cgtaatggaa tttatcatag
    10801 tttcgccaag cagtgcgtgc ttgatcgttt agttttaggc tacccagtcc aatcagaaga
    10861 ctggtgggtt ggtaaaattt ctcaagatca attaagatac tgttgttcaa cttttccgtt
    10921 tttttgagct cttgcatagt agtgtttagc agctcttgta gtcgaatatc atctgccgta
    10981 ccctgtttac agttttggta gcttttattt aacttggata ggagttgaat gagtttcttg
    11041 tcttccatgt gagcatcctc cttgatctga tgtactcttt ccctatagta tagcactaaa
    11101 aaacaaaact gtcatagtaa atatgttaaa attctgaatt ttaattacaa agtttggtgt
    11161 gctgatttgt agccttttca tggtataatc aagagagtaa atctttatgg aggaagtatg
    11221 aaattaaata ttcaagaaat tcgtaagcag tctgaaggtt tgaactttga acaaacgtta
    11281 gatttagttg atgacctgcg tgcacgtaat caagaaattt tagatgtaaa agatatcctt
    11341 gcagttggga aagtacaata tgaagaccgt atgtatttct tagattatca actatcttat
    11401 accattgttc ttgcttcgag tcgcagtatg gagccagttg agttagttga atcttatcca
    11461 gtcacggaag ttttcatgga aggcgcaact aaccatctaa atcaagaaat tttagatgat
    11521 gacttggtct tgcccatcga aaatgaggcg cttgaccttg ctgagagtgt atcagacaat
    11581 atcttgctaa acattcctat caaggtcttg acggctgaag aagaagctgg tcaaggattt
    11641 gtctcaggaa atgactggca aatcatgaca gaggaagaat accaagctca acaagcagta
    11701 aagaaagaag aaaacagtcc ttttgctggc ttacaaggac tatttgacgg agatgaataa
    11761 tggtcttgtc aaaaaaacga gcacgaaagg tgctagaaga aatcattgcc ctcttcccag
    11821 atgccaagcc tagtcttgat tttaccaatc attttgaact cctggttgcg gtcatgttat
    11881 cagcccagac gacagatgca gcggtaaata aggccacacc aggtctcttt gttgcctttc
    11941 caacacccca agctatgtct gtagcgacag agagtgagat tgcttcacat atttctcgct
    12001 tgggattgta tcggaataaa gctaaattcc ttaaaaaatg tgcccaacag ttactagacg
    12061 attttgatgg tcaagtccct cagacacgtg aagaattgga gagtttggca ggtgttggtc
    12121 gcaagacagc caatgttgtc atgagtgtag gatttgggat tccagccttt gcagttgata
    12181 ctcatgtgga gcgtatttgc aaacaccacg atattgtcaa aaaatcagcg acgccacttg
    12241 aggtggaaaa gcgggtcatg gatatcttgc cgcctgagca gtggttagct gcccatcagg
    12301 ccatgattta ttttggaaga gccatttgcc atccaaaaaa tccagagtgt gaccagtacc
    12361 cacaattata tgattttagc aatttgtaag atgctacatt gaaacttttt gcttgatttt
    12421 aagcatgctt tgtgctatag taaatgataa ctaaatattc ctttaaacct gtcccgtgag
    12481 gcaggcaagg agcgcgataa agtagaaggg tgaagtctat actgtgtgca gtagggctcg
    12541 cttggctata aatttcaagt ctccttgttt aaggagactt ttctttttgg aggtttgtca
    12601 tgaaaacaaa agaagttgta gacgaattga ccgtcaaacg agcgattacg cgtattactt
    12661 atgagattat cgaacgcaac aaagatttga ataagatcgt cttggctggt attaaaactc
    12721 gtggtgtctt tattgcccac cgaatccaag aacgtttgaa gcagttagaa aatctttcag
    12781 ttcctgttgt ggaattggat actaaacctt tccgtgatga tgttaaaagt ggagaagata
    12841 cttctttggt ttctgtcgat gtgacagacc gcgaagttat cttggtggat gatgtgctct
    12901 atacaggtcg taccatccgt gctgctattg ataatattgt cggtcatggt cgtcctgcgc
    12961 gtgtgagttt agcagttcta gtcgatcgtg gacatagaga attgccaatc cgtccagatt
    13021 acgttggaaa aaatatccca accagtcgtt ctgaagaaat catcgtagag atgacagaac
    13081 ttgatgacca agacagagtt ctgattactg aagaagctta gaaagttaaa ggagtagcca
    13141 tgtcagaaaa tcaacaagca ttgaaccatg tggtgtccat ggaagacctc actgtcgatc
    13201 aagtaatgaa attgatcaag cgaggaattg agtttaaaaa tggagcccag cttccctatg
    13261 aagaccatcc gattgtttcc aatctcttct ttgaggattc tacacggaca cataagtcct
    13321 ttgaagtcgc agagattaaa cttggattgg aacgacttga ctttgatgtg aagactagtt
    13381 cggttaataa gggtgagaca ctttatgaca ccattttgac tctgtctgct ttaggagtgg
    13441 atgtctgtgt gattcgccat ccagaggtcg actactatag agaattgatt gctagtccaa
    13501 cgattacgac ttccatcatc aatggtggag atggttcggg ccaacaccct agccagagct
    13561 tgcttgattt gatgaccatt tatgaggaat ttggccactt tgagggtctt aaagttgcta
    13621 ttgcaggtga cttggaccac tcacgcgttg ccaaatccaa tatgcagatt ttgaaacgct
    13681 tgggatctga actctttttc gctggacctg aggaatggag aagtcaagag tttgcagact
    13741 atggacagtt tgtaaccatt gatgaaatca ttgatcaggt tgatgtcatg atgtttctcc
    13801 gtgtgcaaca cgaacgccat gatagtggag ctgtattttc aaaagaagac taccatgccc
    13861 aacatggctt gactcaagaa cgttacgatc gtttgaaaga aacagcaatc ctcatgcacc
    13921 cagctccaat caatcgtgat gtagaaatag cagaccactt ggttgaagca ccaaaatcac
    13981 ggattgtcca acaaatgacc aatggtgtct ttgttcgaat ggcaatctta gaatccgtac
    14041 tagcgagtag aaacgccaac taaaacacaa gacgttaaaa gacgccagtg agcgtccacg
    14101 agaggtgaaa atatgacaaa aagaattcta gtattagaag atggcacagt ttttgaaggc
    14161 aaggccttcg gagcagatat tgatgtaaca ggcgaaatcg tctttaatac agggatgacc
    14221 ggctaccaag aatccattac agaccagtct tataatggac aaatcttgac ctttacttat
    14281 cctttggtag gaaattatgg tattaatcgt gatgattatg aatccattat tccaacttgt
    14341 aagggagtcg ttgtttttga agaagcgcgt agagctagca actggcgcaa ccaaatgacc
    14401 ttggatgaat ttttgaaagc caagaaaatt ccagggattt caggaattga tacgcgtgct
    14461 cttaccaaga ttatccgtaa gcatggtact atgcgtgcaa ccttgaccca tgttggggac
    14521 agtatggacc atgtgacgga ccagctccaa gcaacagttt taccgacaga caatatcaaa
    14581 caggtttcta ctaaaacgtc ttatccagct ccaggagttg gtttgagcgt ggtgctagtg
    14641 gactttggtc tcaagcactc aatcctacgt gaactttcta aacgcaactg taacgtgaca
    14701 gttgttcctt attcgacaac ggctgaagaa attctccatc tcaatcctga cggagttatg
    14761 ttgtcaaatg gtccaggtaa cccagaagac gttccacaag cactcgacat gattcgcggt
    14821 gtacaaggaa aaattccaat ctttggtatt tgtatgggac accaactctt tgcaatggca
    14881 aacggggcta agacctataa gatgaagttt ggccaccgtg gattcaacca tgcggtacgt
    14941 gaaatcgcaa caggacgagt agacttcacc agccagaacc atggttatgc agtcagccgc
    15001 gaggatttgc cagagcactt gattattacc cacgaagaaa tcaatgacaa gtcagtggaa
    15061 ggtgtgcgcc acagatacca acctgctttc tctgttcaat accacccaga tgcagctcct
    15121 gggccacacg acgctagcta cctatttgac gagtttatcg agatgatgga agtttttaaa
    15181 caatcaaact aagaacgagt aaaagctcgt cggagaattt atgtaactga acacggacgg
    15241 aaagctcaga atgtagagaa accaacttgg attgtcaatc cttccttgat ttcctaaaat
    15301 tcaatcgctt tctattcgtc ctttgtatct tatttaatgt cgccctgaga ggcgacgaat
    15361 agaaaggaga agggagctcc gtatttgctg aactgaatac gggctacgga cggtgctaaa
    15421 aagatagtta ttcctagaac tgacagttct tcgtcataac tcctatttta gctttgtccg
    15481 cttgacaccc ttaatatctt atatatgcct aaacgtactg atattcaaaa aattatggtg
    15541 attggttctg gtccgattat tattggtcag gctgctgagt ttgactacgc tgggactcag
    15601 gcttgcttgt cgttgaaaga ggaaggttat gaggttgttt tggttaactc aaatcctgca
    15661 accatcatga cggacaagga aattgctgac aaggtttaca ttgaaccgat tacacttgag
    15721 tttgtgacac gtattcttcg taaggaaggt ccagatgcct tgctaccaac actcggtggt
    15781 cagacaggtc tcaacatggc catggaatta tctaaaaatg gtatcctaga cgagcttggc
    15841 gttgaacttc tgggtaccaa attatctgcc attgaccaag cggaggaccg tgatctcttt
    15901 aaacaattga tggaagagct tgaacaaccc attccagaat ctgaaattgt taacacagta
    15961 gaagaagcag ttgcctttgc agcgacaatt ggctacccag tcatcgttcg tccagccttt
    16021 acccttggtg gtactggtgg tggtatgtgt gccaacgaga aagaattgcg tgaaatcact
    16081 gaaaatggtt tgaaattgtc acctgttacc caatgtttga ttgagcgttc gattgccggt
    16141 ttcaaggaaa ttgaatacga agtgatgcgt gactcagctg acaatgcctt ggttgtttgt
    16201 aacatggaaa actttgaccc agttgggatt cacacagggg attccattgt atttgcccct
    16261 gcgcaaacca tgtcagacta tgaaaaccaa atgcttcgtg atgcgagctt gagcattatt
    16321 cgtgccctca agattgaagg tggatgtaat gttcagctag ctcttgatcc taacagcttc
    16381 aagtattatg ttatcgaagt aaaccctcgt gtatcacgtt cgtcagccct tgcttctaaa
    16441 gcgacaggat atccgattgc taagttggct gccaagattg cagtaggttt gaccttggat
    16501 gaggttataa acccagttac aggttcaacc tatgccatgt ttgaaccagc ccttgactac
    16561 gtagttgcta agattccacg tttcccattt gacaagtttg aaaagggtga acgccgtctc
    16621 ggtacacaaa tgaaggcgac tggagaagtc atggcaatcg gtcgtaacat cgaggaatct
    16681 cttctcaagg cctgccgctc ccttgaaatt ggggtgcacc acaatgaaat acctgaactt
    16741 gcagcagttt ctgatgatac cttgattgaa aaggttgtca aagcccaaga tgaccgtctc
    16801 ttctacgtat cagaagccat tcgtcgtggc tacacacctg aagaaattgc agagcttaca
    16861 aaaattgata tcttctatct tgataaactc ttgcatatct ttgaaattga gcaagaattg
    16921 ggtgctcatc cacaagatct agaagttttg aaaacagcca aacttaatgg tttttcagac
    16981 cgtaagattg ctgaactctg gggaacgact gatgataaag ttcgccaact tcgcttggaa
    17041 aacaagattg ttccagttta taagatggta gacacttgtg cggcagagtt cgattccgaa
    17101 acgccatatt tctattcaac ctatggttgg gaaaatgaat ctatcaaatc tgataaagaa
    17161 tctgtacttg tcctaggttc aggtccaatc cgtatcggtc aaggggttga gtttgactac
    17221 gcaaccgttc actctgttaa ggctatccag gcagctggtt atgaagctat catcatgaac
    17281 tcaaacccag agaccgtttc aacagacttc tctgtatcag ataagcttta ctttgagcca
    17341 ttgacattcg aagatgttat gaacgtcatt gacttggaac aaccaaaggg agttatcgtt
    17401 cagttcggtg gtcaaacagc catcaacctt gcagagccat tggcaaaagc aggtgtgacc
    17461 atccttggta cacaggttgc tgacctagac cgtgccgaag accgtgacct cttcgagcaa
    17521 gctctcaaag aattggatat tccacagcca ccaggacaaa cggctaccaa tgaagaagaa
    17581 gcagctcttg cagctcgtaa gattggcttc ccagttcttg tccgcccatc ttatgtactt
    17641 ggtggacgtg ccatggaaat cgttgaaaac gaagaagacc ttcgttctta catgcgaact
    17701 gctgttaagg ctagtccaga ccatccagtt cttgtcgact cttatatcgt tgggcaagag
    17761 tgcgaagttg atgccatttc agatggtaaa aatgtactca ttcctggtat catggagcat
    17821 atcgaacgtg ctggtgtcca ctcaggtgac tcaatggctg tttacccacc acaaaccttg
    17881 tcgcaaaagg ttcaggagac catcgcagac tacaccaaac gcttagcaat cggtcttcac
    17941 tgccttggaa tgatgaacat ccagtttgtt atcaaggatg aaaaagtcta cgttattgag
    18001 gtcaatccac gtgccagccg taccgttcca ttcctatcta aggtaaccaa tattcctatg
    18061 gctcaagtag cgaccaagct cattcttggt caaagtttat cagaacttgg ctaccaaaat
    18121 ggactttacc ctgaaagcac ccgtgttcat atcaaggcac ctgtcttctc ctttaccaaa
    18181 ctagctaagg tagacagctt gctcggtcct gaaatgaagt caacaggtga agttatgggt
    18241 tctgatgcta ctttggaaaa agctctctat aaagcctttg aagcttctta tctacacttg
    18301 ccaacttttg gtaatgtcgt ctttaccatc gctgatgatg ccaaagaaga agccttgaac
    18361 ttggctcgtc gtttccaaaa cattggttat ggaatccttg cgacagaagg gacagcagcc
    18421 ttctttgcta gtcatggctt gcaagcccaa cctgttggta agattggtga tgacgataag
    18481 gatatcccaa gttttgtacg caaaggaaga attcaagcta tcattaacac agtaggaaca
    18541 aaacgaactg ctgacgaaga tggtgagcaa attcgtcgtt cagccattga acacggggtg
    18601 cccctcttca cagcgctaga tacagctaat gccatgctta aggtacttga aagtcgtagc
    18661 tttgttacag aagcgattta aatagaaaaa taagatatag caga
//
LOCUS       DAVLBN010000041        18468 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLBN010000041 DAVLBN010000000
VERSION     DAVLBN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.041"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..170)
                     /locus_tag="VXC24_001442"
                     /pseudo
     CDS             complement(1..170)
                     /locus_tag="VXC24_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(216..449)
                     /locus_tag="VXC24_001443"
     CDS             complement(216..449)
                     /locus_tag="VXC24_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0493544.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VXC24_001444"
     CDS             complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VXC24_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0493545.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VXC24_001445"
     CDS             complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VXC24_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0493546.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2211..3380)
                     /locus_tag="VXC24_001446"
     CDS             complement(2211..3380)
                     /locus_tag="VXC24_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0493547.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3529..4539
                     /locus_tag="VXC24_001447"
     CDS             3529..4539
                     /locus_tag="VXC24_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0493548.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(4775..5212)
                     /locus_tag="VXC24_001448"
     CDS             complement(4775..5212)
                     /locus_tag="VXC24_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0493549.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5297..7930)
                     /gene="polA"
                     /locus_tag="VXC24_001449"
     CDS             complement(5297..7930)
                     /gene="polA"
                     /locus_tag="VXC24_001449"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0493550.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(8539..8789)
                     /locus_tag="VXC24_001450"
                     /pseudo
     CDS             complement(8539..8789)
                     /locus_tag="VXC24_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8782..8898)
                     /locus_tag="VXC24_001451"
     CDS             complement(8782..8898)
                     /locus_tag="VXC24_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0493551.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(9113..9466)
                     /locus_tag="VXC24_001452"
     CDS             complement(9113..9466)
                     /locus_tag="VXC24_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0493552.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(9584..10552)
                     /locus_tag="VXC24_001453"
     CDS             complement(9584..10552)
                     /locus_tag="VXC24_001453"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0493553.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10697..11257)
                     /locus_tag="VXC24_001454"
     CDS             complement(10697..11257)
                     /locus_tag="VXC24_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0493554.1"
                     /translation="MSNFLGSVHLLGVLFPDSTFLNAFESAIVAPLVEESLKLLPLVF
                     VLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIHTDLPEGFDFTISRILERIISGIAS
                     HWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAI
                     PVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(11263..12614)
                     /locus_tag="VXC24_001455"
     CDS             complement(join(11263..12173,12173..12614))
                     /locus_tag="VXC24_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0493555.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(12611..12955)
                     /locus_tag="VXC24_001456"
     CDS             complement(12611..12955)
                     /locus_tag="VXC24_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493556.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDFMNCTPKV
                     RQKKSNFWGVLL"
     gene            complement(12976..13473)
                     /locus_tag="VXC24_001457"
     CDS             complement(12976..13473)
                     /locus_tag="VXC24_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0493557.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(13546..14907)
                     /gene="radA"
                     /locus_tag="VXC24_001458"
     CDS             complement(13546..14907)
                     /gene="radA"
                     /locus_tag="VXC24_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0493558.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(14921..15436)
                     /locus_tag="VXC24_001459"
     CDS             complement(14921..15436)
                     /locus_tag="VXC24_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0493559.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(15438..15881)
                     /locus_tag="VXC24_001460"
     CDS             complement(15438..15881)
                     /locus_tag="VXC24_001460"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0493560.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(15941..16034)
                     /gene="ffs"
                     /locus_tag="VXC24_001461"
     ncRNA           complement(15941..16034)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXC24_001461"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(16067..16534)
                     /locus_tag="VXC24_001462"
     CDS             complement(16067..16534)
                     /locus_tag="VXC24_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0493561.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(16735..18021)
                     /locus_tag="VXC24_001463"
     CDS             complement(16735..18021)
                     /locus_tag="VXC24_001463"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0493562.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(18252..18464)
                     /locus_tag="VXC24_001464"
     CDS             complement(18252..18464)
                     /locus_tag="VXC24_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0493563.1"
                     /translation="MANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRD
                     FIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         5405 a         4532 c         3204 g         5327 t
ORIGIN      
        1 ttctcaacct tgcttctctc cttagatagc gcatgattac aggctttatc ttcaactgtt
       61 agcggcttga gtttgctgga tttacgtgga gtttgtgctt gaggatatat cttcatgagc
      121 ccttgataac cactgtcagc caagatttta ccagcttgtc cgatatttct catttctaaa
      181 aaccatctac ttccgttgac ttggaactcc gattgctatt ttccttgaat gattttaacc
      241 acatctccta cgttttggag ttggtcaatt tcttcatcgc tgatttcgat actaaattca
      301 tcttccaggg tcaagataaa ctccatcaag tcaacagaat ccgcatccaa atcgtctttc
      361 agactcaagg attctgtcac gacaaagtcc tctccctgtc gctcttggat aatggtcaca
      421 atacggtcaa aaatttcttt ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag
      481 tctgggcaac tacgtctgtt tctagcatgg tacgaatctg gcgaatcgta ctataaacag
      541 ccttggcatc gcttgagcca tgagtcttga caacaggtgc cttaacacca aacaagaccg
      601 ctccaccaac atctgaataa ttgagctgtt ttttcaaacc tctgaggctg tccttgagaa
      661 ggagggcacc tagtttcgct cgaagaccac cacctgtaat agctgtcttg agcaagccca
      721 tgattcccat agctgtccct tcgatggatt tgagcacagc gtttcccgtg aaaccatctg
      781 ccacaacaac atctgcaacg ccattcatca aatcacgcgc ttccacgttt ccgataaagt
      841 tcaaactttc atcagccgcc agtaattcat aagtttcctt acgaagcggg tcgcccttgc
      901 tactctctgt tccgttgttg agcaaaccaa cgcgtggttg cgcaatgcca cggacatttt
      961 tagcatagaa ggaacctaga accgcatatt gatggaggtg ctgggctgta ttttctgcat
     1021 tggcaccaag gtctagcatg tcaaaacctt ttccatcaac ggtaggcaag gtagacatga
     1081 gtccaggacg gtcgatattc ttgatacgac ccacgatgaa gaatcctgct gccaacaagg
     1141 cacctgtatt cccagccgaa aggacagcgt ctgcttcacc atctttgaca gccttggctg
     1201 ccaataccat actggcattt ttcttattcc taatagctct cgtaggttca tcatccgaat
     1261 caatcttctc atccgtatgg ataatgctga cgcgctctgt cgctgtcaga tattgcttga
     1321 ttttagcttc atctccgtaa agttgaacct cgatatctga aaagtcagat agggcttgat
     1381 tgacaccctc aacaatggcc tgaggtgcgt aatcgccccc catggcatct actgcgattt
     1441 ttttcatttc ttttcctctt ttagtaattg tccccagtct gctagggaat caataaattt
     1501 ctttgatttt aggtgaatcc caacgtactc ttcatataat tgatccataa attggcgtag
     1561 ctcttgcttg attccaggct tgagcgaaat ggtctccaaa gtctcaaaat caatagcttg
     1621 aaattgattg agcagatagg ggatattggg attgagatga caacgtctct tatcctcatg
     1681 ataatgctct ggacagaggc aggctccata tttgaaagaa aagtcaaaag cctgaccaac
     1741 ccgatggcag aagacacact cattaaaatt gaggctgatt ccaaatcgag tcaaaatttg
     1801 aatttcaaaa atattggtca aaacctgata atccaagcct gcttccatca actccaaagt
     1861 cttttgcaaa aaagcaaaca agggagcatc ctgctgattg tcctgcaaac tagcatctgc
     1921 aagagctgcc acataggtcg cataggccat gacaaagagg tcactattaa tcttgggaaa
     1981 agtcatgacc tcatgatagt cttcgatgta actgagtccg tcatcattga ttcgcaagag
     2041 aaatcgtgcc agcaccaagg gctgaataac aggcgccagc ttagactgac cagcgtgttt
     2101 gacaaaaaac atgcatttgc caacctgctc tgtaaaaatt ttgacgagct tgtcatcctc
     2161 acgaaaattg cgattgtaaa gcaccaagcc ttgactcgtg atagactgaa tcatgcttct
     2221 ctcatgtact cctcaagtcg tttcatggct tctttgatag tctccatgct ggctgcataa
     2281 gataggcgga cgtagccttc cccgtaacgt ccaaaggctg caccagggat aaaggcaacg
     2341 gccttcttct gagcaaaatc cttcagaaaa gcaaaggagt cttgattgta gcccgctgga
     2401 attttagcaa aaatatagaa ggcaccgtct ggtttgataa tctcaaaacc aagagcagtc
     2461 attttttcga tgatatagtc ccgacgctgg atatattcct tcttcatggg ctccgcatca
     2521 tttttaccag ccgtcaaggc ttctaccgca gcatgttgcg ccatggtatt tgcggcagtg
     2581 accaagtact ggtgactctt gattaactgg gctgtgaagg tcgccggagc gaaaatcagc
     2641 cccaaacgcc aacctgtcat ggcatgcgat ttagacaaac cattgataat aatagcctgg
     2701 tctctcaaca tcgttcctag agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa
     2761 acctcatcac agacaacaaa aacttcgtac ttgcgtaaaa cagctgccaa ggcctctaac
     2821 tgctctcgac tgtaggtaat tcctgtcgga ttggctggat agttgagaat aaccgctttg
     2881 agcttatcac cctgctccaa aatggccttc tccaacatct caggagtcaa gacaaaacca
     2941 ttttcagtcg tatcaatctc aacaatttct gccccaacta agttaacaat cggttcatag
     3001 cctggataag caggagctgg caaaagtacc ttgtctccct cttccaaaat agccgtcaaa
     3061 gtcgcagata aagcctctgt cgccccaatt gtaaccaaga tttcattttc aggagcatag
     3121 tccagttggt acttttcctt aacaaagtca ctggctgcct gacgtagagt cagcagacca
     3181 ctcatccctg tatagtagga ttggttctga tcaatcgctc gcttggccgc ctccttgaca
     3241 tggtctggcg ttgtaaaatc aggttccccc aaggtcaaac gcaagacccc aggaatctcc
     3301 gaaatagcct ggtcaaactg acgaatcaac gaaacttgaa ttttatctaa ctgtttatta
     3361 aagcgcttag ttaagtccat agatacctcc tactttcaaa acgtatctct attatactac
     3421 aaaagccccc cgaccgcaaa aatacattag agaatagctt tccactttct attttacttt
     3481 tcctgtttat aggtctataa tggtaataga ttttatttgg aggtttttat gtcatttcta
     3541 tcaaaaaatg gagcaggtat cttggcctgc cttctcattt ccatcctatc ttggtactta
     3601 ggaggattct tccctgtgat tggcgcgccc gtttttgcca ttttcatagg catgctccta
     3661 catccctttc tctcgtccta taaacaactg gatgctggtt tgacctttag ttccaagaag
     3721 ttgctccaat atgccgttgt cttgcttggt tttggtctca atatctcgca ggtcttcgca
     3781 gttggccaat cttcactccc tgtcatcctg tccactatct caatagctct gattattgcc
     3841 tacctcttcc agcgtttctt tgcactggat acaaaactgg ctaccttggt tggagtaggt
     3901 tcttctatct gtgggggttc tgccattgca gcgacagcgc ccgttattga tgctaaggaa
     3961 aaggaagtag cccaagccat ttccgttatc tttttcttca atgtcttggc tgcgctcatc
     4021 tttccaaccc tcggcacctg gcttcatcta tccaatgaag gcttcgccct ctttgcaggg
     4081 actgcggtca acgacacttc ctctgtaacg gctgccgcca gcgcttggga cagtctttac
     4141 caaagcaata ccctcgagtc tgcaaccatt gttaaactca cacgtacttt ggccattatc
     4201 cctatcacgc tctttctatc ctactggcaa agtcgccaac aagaaaacaa gcaaagccta
     4261 caactgaaaa aagtcttccc actttttatc ctttacttta tccttgcatc gctcctaacc
     4321 acccttctga cctctctcgg tgtgtctagt agtttcttta cccctctcaa acaactctct
     4381 aaattcctca ttgtcatggc catgagtgct atcggtctca aaaccaatct ggtcgctatg
     4441 gtcaaatcca gtggaaaatc cattgttctc ggagccatct gctggattgc catcatcctc
     4501 accactcttg gtatgcagac ccttatcggc attttctaat actcttcgaa aatctcttca
     4561 aaccacgtca acgtcgcctt gccgtatata tgttactgac ttcgtcagtt ctatctgcaa
     4621 cctcaaaacg gtgttttgag ctgacttcgt cagttctatc tacaacctca aaacagtgtt
     4681 ttgagcagcc cgcggctagt ttcctagttt gctagtttgc tctttgattt tcattgagta
     4741 taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc aagcgagtat
     4801 gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca cgcaaaatct
     4861 ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca tcagctttga
     4921 gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg acaatatcta
     4981 caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt tcgccacctg
     5041 ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc tttgttactc
     5101 gattgctagt tgtttcttca cggtcagaca aacccaccac agcaagggtt ttactcgttg
     5161 cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc atagaaatcc
     5221 tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact acaaaaaagg
     5281 aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc tcatctgcga
     5341 taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat tttttcatct
     5401 ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt aacagcatct
     5461 tagtctgata accacctgca accaaggctt tatccagctg aatcatggca atcttgagaa
     5521 tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca aaaccacgaa
     5581 tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag agggtctcta
     5641 catagccctt atcacgcgcc tcccgcacca cttcatccat gtagttttta atacctggaa
     5701 aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt cccaaattat
     5761 tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc ttggcattgc
     5821 gacggtcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc atggctgtcg
     5881 aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat
     5941 gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca ctatcctccc
     6001 actctggcac aaaagccttc cgaatcaagc gcccttgttc caatcgagca ggaatatttt
     6061 gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc atatagcgag
     6121 tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa gtagattgaa
     6181 tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata ggagcgagac
     6241 gctccaacac atccactgct gtcgaataac ctgtcttggt tttcttagtg tattctagag
     6301 gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg acattaaact
     6361 cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc tcattttcag
     6421 cctgcatctc aagcaaggtc tctttcttga ccacaatccc agcaatttcc atcttggcaa
     6481 gaacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca ttttcgctga
     6541 gtttttcaag taaaataggc tctgttccta ccaaaacagc aagtttacaa gctaagtgtt
     6601 ccaagaattt ctcacgttca ggaatggcct ttttaacacc cttaccgtag aaagtttcat
     6661 catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca ttgtcctcca
     6721 cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc aaatccacac
     6781 caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga gatgtttttt
     6841 ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg gcatagagct
     6901 tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc tcaccaaaaa
     6961 gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg tcaacaatag
     7021 taaaatccaa accctcagcc acatcagctg acgacacatt taaagcctgc ttgagctgtt
     7081 tgaagcccat ctcatcgtaa aatttcccaa gattttcaac atctggacca ctatagacca
     7141 agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt gttttagaca
     7201 aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc ttcattccat
     7261 caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta atacccgtct
     7321 tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg agcgccttga
     7381 gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct ggcgtaaagg
     7441 cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca tccgtcagct
     7501 gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc tctgctagct
     7561 tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag tgacgaatcc
     7621 ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca tcaggagtct
     7681 tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc tttcccgcat
     7741 caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc aacatcaact
     7801 gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg tccaactgct
     7861 gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat aataattttt
     7921 tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg aagagctaga
     7981 gcaagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt tagtaaacct
     8041 agatttaaaa atgtgatata atatagtata ttgaatctat aatagtacac cttgactgct
     8101 aaaatatttc tataaattaa tttgactttc ctgatagagt tgtttcacat cttatttcaa
     8161 ctcactatag aaggaggaaa aggagggctg ggtggctaac ttcattatag aactttcaaa
     8221 aagatgaaaa aatagcgtca aagaggcttt tttctcttta aaacaggaaa tttcaaagac
     8281 aatcttgcga ctatccaaac tgtacgaata gcgagacata acttacttcg ctaatactat
     8341 agtagattga aactagaata gtacacctcg atttctaaaa cattgttaga aatcgatttg
     8401 actgtcctga acgatttgtc ctgttattat ttcattttac tatatcttat aaaaagatag
     8461 aaatgtcaag caaaaatgac aagtattttg ataataaact tgccatccca tcaactttct
     8521 actatataaa gtatgaactc atagcaagga ctcaaactca gccacggtca tgcctaattg
     8581 ctcactcgca acctcaggtg ttagaagacc ttgacgtact agatttacta aacctacttt
     8641 taatccctct tcaaggcctt cttctcgtcc ttgttcacaa ccctctgcac gaccacgttc
     8701 aataccacgc tctagtcctt gttcaatacc ttcgcatagt cctgtgctaa caagacttgt
     8761 tcttctcgca tatgtagttg actaaacatt ttcctgtcct cctcggacca gctcttgtag
     8821 tccagcagtt gatttgcttg ggtaatggct cgttgcggtt gctgggtaaa gggcttgttg
     8881 ccgaaaaact ccaaccatgg cttgcgaacc ttgtctttgc tggtttctct gtatttttta
     8941 attccaagaa tgccatctta accagatggt tttcctgtcc attgttggta atcgccaata
     9001 cctcacctgt tgtgtcttcg cgcatactaa cgctatgaaa agccaggcca tctgagaaat
     9061 aattgctatc cacgatagca atgacgtaaa caggagcgat gtgtttgtag atctagtgag
     9121 tatcaccttc tcgctgacga attttttcaa gattttgatt aacctgactg cacaggtaag
     9181 cccacaagtg attgatgaaa aaattctgat gatggacttg aatctcaata attacttgag
     9241 taccgttatc caactccgcc aagacgtcta tactggtata aaaatcctgc accgagtaag
     9301 gcatggagag taatacgtga atattgctac cctccaaaat ggtcacattt tgggctggca
     9361 aatccagcat atcgcgaata aattgacaag taatttctgg attgctaaag attttcttag
     9421 ctaccaagtc attggttggg ctaatgcccg gatgacgtac agtcatattt cttctctttt
     9481 tattatatca cagttttaaa tctagcttta ctagattcac cgctactatc tatttattcg
     9541 gaaaaaagac gaaaaaacct gagaatcatc tcaggcttgg tcattaaatt tttttctcaa
     9601 tatcgaaaag tggagaaagt ggtcgttttt catgaatacg tacgatagca tcccctagga
     9661 gatgagcgat tgaaatctgc tcaatcttat caatcaaacg ctcttctggc agatagatgg
     9721 tatccaaaac aaccaatttc ttaatagctg atttttggat attgtccgta gcaggaccag
     9781 aaagaactgg gtgcgtacag cttgcataga cttcaacagc accagcttcc gcaagagcat
     9841 ctgccgcatg acaaatcgtt ccagcggtat caatcatatc atcaatcaag atacaagtct
     9901 tgccttcaac cttaccgatg atgttcataa cttcactagt attcatctta tcaacgctac
     9961 gacgtttatc aataatagcg atagaagttt tcaaaaattc tgccaactta cgagcacgag
    10021 tcacccctcc atggtccggg ctgacaacca catagtcaga accaaccata ccacgacgct
    10081 caaaataatc tgcaatcaga ggagcaccca tcaaatgatc cacaggaata tcaaagaatc
    10141 cttgaatttg cgcagcatgc aagtcgatgg tcaataaacg atccactcca gctacttcaa
    10201 gcatatttgc gacaagtttt gaagtgattg gctcacgcgc tctcgccttt ctatcctgac
    10261 gtgcataccc atagtaaggc atgacaacat tgacagattc tgcactcgca cgcttcaaag
    10321 catctaccat aatcaaaatt tcaagcagat tgtcatttac aggcgaacta gttgattgta
    10381 ggataaagac gtgtttccca cggattgatt cttcaatgtt gacctgaatc tctccatctg
    10441 aaaattggcg aacacttgat ttccccaact ctatcccaat ctcctgcgcc acacgttctg
    10501 ccaattcttt attagaagaa agggcaaata gctttaaatc agaaaaagac atgatttcct
    10561 ccggtatata tgtataactt gtgcttttca caagattttc catctaccat tgtagcgctt
    10621 tttgcactat ttttcaatca aaaataaaag aagggcacca tatttgtacc cttgcatcat
    10681 tcttttgaaa aatattctag gtcatcaact cattgtgttt ctcaacaaag caataagcat
    10741 gataaaaacc atagagagca atagccgtaa ccactggaat cgctaaaggc aactctgttt
    10801 ccaactccac aaaaggagag ttaaacaaga agtgagttcc caaggctaaa cctagaaaaa
    10861 taaggccctg tttcttgcca accttctgtc ctttataggc tctgtaaagc aagtaaacac
    10921 ctactacagc tagacctgaa aaagtccagt gagaggcaat tcctgagatg atacgctcta
    10981 aaattcgcga aatagtaaag tcaaagccct ctggcaaatc cgtatgaata taaccaatat
    11041 cctcaatcat ttggaatccc aaaccggaag caattccaag taaaaacaaa gattttaatt
    11101 ttcgcacagg aatcaaagcc aaaacaaaaa caagtggcaa taatttcaag gattcttcta
    11161 ccaaaggagc cacaatagca ctttcaaagg catttaaaaa tgtactatct gggaaaagaa
    11221 cccccagtaa atgtactgac cccaaaaagt tagacaaata atttatccaa aggatttagt
    11281 tctgtactgc acagaactaa gtccttttag ttttacctta attcgtttgt tgttgtagta
    11341 atcaatgtag tccacaatag cttgttcaag gttttctaaa gatctaaagt tcttctcata
    11401 gccataaaac atttcggatt ttaaaatgcc aaagaaagat tccatcatgc tgttgtctgg
    11461 gctgttgccc ttgcgtgaca tggatgcttg aattccctta ctctctagga accgatgata
    11521 agaatcgtgt tggtattgcc agccttggtc actatggaga atcgtattct catagtattt
    11581 ctctgtaaag gcctgttcta acatactctt cacttgttct aagtttggcg aagtagaaag
    11641 atgataagca atgatttcac tgttaaaacc atctaaaact ggtgataaat agagtttctg
    11701 tgtgctattt ggaatggcaa actctgtcac atctgtatag cacttttcca ttggcctcga
    11761 tgcttcgaac tggcgttgaa tgagattctc tgctttcttg ccaatctctc cttggtagga
    11821 agaatacttc cgtttacggc gaattcgagc cgttaaacca agaattctca tcaaccgttg
    11881 aactttctta tgattgacca caaaaccacg attccttagt tctaaatgga ttcgacgata
    11941 gccatagttg cctttatgtt cattatcaat gccctgaatt tcggttttaa tctctttatc
    12001 tttatcaacc ccatccagtt gtttcaactg ataatagtaa gtcgagcgag ctaaacgtgc
    12061 tgtttcaaga agaaaatcta gtcgaaatcc tcctgaaacc atttctctaa ctgtctctgc
    12121 ctttctcgct ctagggcttc gtccctttcc tctaactctt ttaacttttt taggtaggcc
    12181 acctcagtcc gtaagcgttc attctcctcc tggagtcgtt ctagttctgt catttcttcc
    12241 caagtcttct tccgtttacg tcccatttta gctggtctcc ctcttgtttt ctcaacaata
    12301 gtatacccgt ttttcttgta ttgtgccggc caaaatgaaa gcattccttg gtttgggagg
    12361 gcataatcaa gactaatact tctttgtgaa caaccttcca gtaaggcttt atccatcatt
    12421 tcttgtttca atttagaaga atagtgacga ttcttccctt ttttaacgat ttctatgcca
    12481 taacggtcaa ttaatttcac catgtacttt agaccagaaa catccacacc aaatcttttt
    12541 gaaagctgtt tgaagctttg tccttgcttt cttagttcat agatctgaac tttatcttca
    12601 taactcaatt tcataataaa acaccccaaa agttagattt tttctgtcta acttttgggg
    12661 tgcagttcat aaaatcatgg atataagtat tagcaaaact agacaaccag cctgaaagga
    12721 acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat tttttcccaa
    12781 tacggaagag aaaataaaga gccggaatca tgtaaaagag agctagaaag atagaaactc
    12841 ccattagtcc atattccgca cctgacctcg aaccgtccgt atagtagatg gtttcatact
    12901 gtaaaccaat acatagcaat aaaataaaaa taaaatactg cttttcttca tacactttct
    12961 ttctaaatga agtatttata attctacgac tgtcatactt cctgtatcaa cattgtaaat
    13021 agcaccagag ataatgacat cgtctggtat taggggagac tcgataagca gttgcatatc
    13081 ctcgcgtaca ctctcttcta tatcttggaa gggcaagaag tcctggtctg acacatctac
    13141 acctaattcc tcttttaaat actcctgaaa aggttcattt tcaaaggtct gagcaccaca
    13201 gtctgtatgg tgcaatacca caatctctct tgtccccatt tgttgctggg aaataactag
    13261 cgaacgaatc atgtcttcag tcactcgacc acctgcattc cgcaagatat gagcatcccc
    13321 aagtgccaaa cctagagctt gcgcaacgtg caaacgtgag tccatacagg tcacaatagc
    13381 tactcttgtt ttgggtttaa gtggcagatt taactgccca tgtagggcaa cataagcctg
    13441 attagcttgc ataaactgtt caaaatacga cacgattccc tccttgaaaa tttgatagtc
    13501 aaatatttct cctatcttat catttttaag agaatttgtc acggattatg caaagacctt
    13561 tttcaaaact tcctgaatcg ttgtcacgcc aatgacctga atttccttag gcagagtgat
    13621 tcctgtcaag gaattcttag gtacataaat cttagtaaag cccagtttag cagcttcgtt
    13681 gatgcgttgc tcaatacgat tcacgcgccg aatctctcct gtcaagccca gttctccgac
    13741 aaaacattcc tgaggattag ttggcttgtc tttgtagctc gaagcaatag caactgcaac
    13801 agccaagtca atggcaggtt catccaattt aacaccacca gcagatttga gataggcatc
    13861 ctgattttgc aagagaagcc ctgcccgttt ttccaaaaca gccataatca agctagcacg
    13921 gttaaaatca agtcctgtcg tagtacgctt ggcatttcca aacatggtcg gtgttaccaa
    13981 agcctgaacc tccgccaaaa tcggacgcgt cccttccatg gttacaacga tggaggaacc
    14041 agttgcccca tccaaacgct cttctaggaa aacttgactc ggattgagta cctcaaccaa
    14101 gccgcccgac tgcatctcaa aaatcccaat ctcattagtg gaaccaaaac gatttttgac
    14161 cgctctcaaa atacgaaagg tgtggtgacg ctccccttca aagtaaagca ccgtatccac
    14221 catatgctcc aacatacgag gcccagccaa ggttccttct ttggtcacat gacctacgat
    14281 aaagatggca atgttattgg tcttggccaa ctgcatgagt tcagcggtca cttcacgtac
    14341 ctgagaaaca gacccctgca cccctgaaat ctcaggagac atgatggtct ggatggaatc
    14401 aataataaga aagtctggct ggatacgctc cacttctgca cgaacactct gcatattggt
    14461 ctctgcatag agataaaact cactatcaat atcacctaag cgctctgcac gtagtttaat
    14521 ctgctgggca gactcctccc cactgatata gagaactgtc cccacttggg acaactgggt
    14581 tgagacttgt aggagaagag ttgatttccc aatcccagga tccccaccga tgaggacgag
    14641 acttcctggt accactccgc ctccaagcac acggttgaat tcctccatct ccgtcttggt
    14701 tcgattgaca ttgatggaag tcacctcagc tagtttcatg ggcttggttt tctcacctgt
    14761 caaggacaca cgcgcattct tgacctcggc aacctcaacc tcttccacaa aagaagacca
    14821 agacccacag ttggggcaac gtcccagata tttaggggaa ttatacccac aattttgaca
    14881 tacaaatgtc gcttttttct ttgcgatgac aaacctcttt ctatatctct aactcacact
    14941 caatcacttg gcaaaaatca atcttctcat ttggcacaaa ctggcgcatg agcattcgat
    15001 gagcaacaac taccacagtc tgatgttctc gatacttaga catacattct agaaaccgag
    15061 acttcatttc cgtagctgtc tcatattgaa taggactatt aggaagcaac tcccccttgt
    15121 tttctaaaaa cagtcttcta gctgtttcaa agttttctat tcctgtttta tagacctgcc
    15181 attcatgtaa taaaggctct actcttaaag gaagacccgt agcacagacc acatacgaag
    15241 ccgtttctaa agctcttgtg actgcagaag atacgattat ttcagctgac gagagtaaag
    15301 gagttttgct caatttctgg acttgctgcc gtcccatctc agacaagggt gccaaatcta
    15361 tcccaaatcc tatataagaa cgctcctcta actcacggta atctggctcc ccatgacgta
    15421 caaagataat cttcattcta gtgccctgtc gatccaaatc caccagttcg aacgccatca
    15481 gctgcatctc catctgcaat taagaaagta gcaaaaacag cctggacaat acgttcccca
    15541 acttcaagaa caacctcttg gtctgtgata ttcttcatct gcgcaaaaat atgcccttca
    15601 tttccaggat ttccataata atccccatca atgaccccaa ctgagttaat taaaaccaag
    15661 cccttcttac gaggatttga agaacgatca tagaggtaga gaacctcagt cggctgcata
    15721 taagccttaa cccctgtcgg aaccaagaca atctctcctg gcgcaacaac tgtacgcaca
    15781 gcaaccttta agtcgtaacc agccgcatgc gctgtctcac gcttgggcaa taaattttca
    15841 tctgtaaaac tcgaaaccaa ttcaaaacca cgaattttca taattttctc ttttctatta
    15901 tcatttattc tagattattc tatcttattt attcggaaaa agcacgaaaa aagagcacac
    15961 aattcaaatc gcttagggct gctggattcc tcccctgacc cgcttcacgc agaactgttg
    16021 ctccactatt tattatatca cattcctatt cattttaaaa gcaaaattat tttttccgtc
    16081 tatttctaaa aaaatcctgc atgatagctg cgcattcatc ttccaaaatt cctatttcaa
    16141 cctccacacg atgattgaga cgctcatctg tcaagatatt gtacaaactc ccagcagcgc
    16201 caaatttctg gtttttagcc ccatagacca catttggaat gcgggcaagc ccaatcgctc
    16261 cactacacat gacacaaggt tcaatggtca caaaaagtgt gcaatccagc aagcgccagc
    16321 tctcctcact caagttcgca tcctctatag ccataatttc cgcatgcata accgctcgct
    16381 gtaattcctc acgcgcatta tgcccacgac caatgatttc cccatctttg acaatcacac
    16441 aaccaattgg aatttcatcg tgttcaagag caatctcagc ctctctcaaa gcctccctca
    16501 taaagacttc tttttcttca agcgtataat acatctcttt tctcttttcc tacttatcga
    16561 ttttattatt atatcatgaa tcccaacaca aaagaagcca ccgaatgcgg tgactctata
    16621 gggagattat tatgaaaaag aaaagtttag gatatttgtt acaacaagtt aggaggtctt
    16681 cttgtaaccg tctatagtat acccgaccta tcttaaacaa atcttaaaaa tctcttagga
    16741 ccaaacactt tctaaaatat ttgtttgttc acgaccagga cctactgaga aagtagaaat
    16801 acgaacgcca accaattcac tcacacgacg aacatagtta cgcgcattct caggaagatc
    16861 ttccaaattg cgaactccgg taatatcttc tgaccaacct ggcaactctt catagatagg
    16921 cttgcaacgt ttcaattgct caagactagc tggatagtag tcaatacgtt gaccgtcaag
    16981 atcataggcc acacagattt tcacagtatc caaaccgctc aaaacatcaa tagagttcaa
    17041 agaaaggtta gtaataccag aaacacgacg gctatgacgc atcacaactg agtcaaacca
    17101 acctacacga cgtggacgac cagttgttgt accatattca tgacccactt cacggatacg
    17161 ttctcccact tcatcaaaca actcagttgg gaaaggacca tctcctacac gactcgtata
    17221 agctttacat acacctacaa ccttgtcaat cttgcttgga ccgacaccag aaccaattgt
    17281 cacaccacca gctacagggt ttgatgacgt aacaaatgga taagtacctt ggtcgatatc
    17341 tagcataaca ccttgtgcac cttcaaaaag cacacgtttg ccattatcaa gcgcatcatt
    17401 caagataaca gatgtatcta tcacgtattt cttgatttgt tgaccatatt cgtaatattc
    17461 ttcaaaaata tcatcgaaaa caatcgcttt actgtcatac aatttttcaa aaagacgatt
    17521 cttttcagca aggttacgtt ctaaacgctc acggaaaata tctttatcta aaagatctgc
    17581 aatacgaatt ccaacacgag cagccttgtc catataagct ggaccaattc ccttaattgt
    17641 cgtaccaatc ttattgtcgc ccttagcttc ttcttgcaag cgatccaact cgatatgata
    17701 aggcaaaata acatgcgcac gatcagaaat acgcaagtta tcagttgtta caccttcctc
    17761 atgaagatag ctcaactctt ttacaagaga tttaggattt acaaccatac cattcccaat
    17821 gacagatatt ttttcaggga agaaaatccc agatggaatc aagtgcaact taaatttctt
    17881 accgtcaatc acaatcgtgt gaccagcatt atcaccacct tggtaacgtg caattacttc
    17941 tgcattcgct gaaaggaagt ctgtaatctt ccctttacct tcatcacccc attgggtacc
    18001 tacaacaaca actgaagtca taattttgtc tgagccctca ggctcttcct ttctcacata
    18061 catggcagga ctctcacctg caattatatc ttacaattta ttataataaa aaatcgcctt
    18121 tttatcaaga agaaacaata gaaagatttg ctatttccaa ctattaaaaa atgatttaga
    18181 aaaattacta gctatttact attatctttc cataaaagag taaattagtt cggaaattta
    18241 ctaaaattac ctcaacaaga aataaacccc cgattcatta ccaatttttc aagatacaaa
    18301 cgataagcaa cacgataatg gtaaacgata aaatccctac gacaaccaat gccatatctc
    18361 actaaataat aaattaaaaa tttaaaatga acatgttccc agtcaaaatt atcaccaaat
    18421 gtaggaccat actcttcttc aatactatca tagaaattag ccatctgc
//
LOCUS       DAVLBN010000042        18183 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLBN010000042 DAVLBN010000000
VERSION     DAVLBN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.042"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            859..2118
                     /locus_tag="VXC24_001465"
     CDS             859..2118
                     /locus_tag="VXC24_001465"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0493564.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2134..2685
                     /locus_tag="VXC24_001466"
     CDS             2134..2685
                     /locus_tag="VXC24_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493565.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2678..3955
                     /locus_tag="VXC24_001467"
     CDS             2678..3955
                     /locus_tag="VXC24_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0493566.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            3971..4831
                     /locus_tag="VXC24_001468"
     CDS             3971..4831
                     /locus_tag="VXC24_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0493567.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5054..5164
                     /locus_tag="VXC24_001469"
                     /pseudo
     CDS             5054..5164
                     /locus_tag="VXC24_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            5210..6014
                     /locus_tag="VXC24_001470"
     CDS             join(5210..5578,5580..6014)
                     /locus_tag="VXC24_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0493568.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            6206..8497
                     /gene="pcrA"
                     /locus_tag="VXC24_001471"
     CDS             6206..8497
                     /gene="pcrA"
                     /locus_tag="VXC24_001471"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0493569.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8540..9220
                     /gene="radC"
                     /locus_tag="VXC24_001472"
     CDS             8540..9220
                     /gene="radC"
                     /locus_tag="VXC24_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0493570.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9217..9906)
                     /locus_tag="VXC24_001473"
     CDS             complement(9217..9906)
                     /locus_tag="VXC24_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0493571.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9924..10565)
                     /locus_tag="VXC24_001474"
     CDS             complement(9924..10565)
                     /locus_tag="VXC24_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0493572.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10648..10863)
                     /locus_tag="VXC24_001475"
     CDS             complement(10648..10863)
                     /locus_tag="VXC24_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0493573.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(10871..11218)
                     /locus_tag="VXC24_001476"
     CDS             complement(10871..11218)
                     /locus_tag="VXC24_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0493574.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11223..12338)
                     /locus_tag="VXC24_001477"
     CDS             complement(11223..12338)
                     /locus_tag="VXC24_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0493575.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12348..13307)
                     /locus_tag="VXC24_001478"
     CDS             complement(12348..13307)
                     /locus_tag="VXC24_001478"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0493576.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13420..13989)
                     /locus_tag="VXC24_001479"
     CDS             complement(13420..13989)
                     /locus_tag="VXC24_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0493577.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14117..14788
                     /locus_tag="VXC24_001480"
     CDS             14117..14788
                     /locus_tag="VXC24_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0493578.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            14772..15590
                     /locus_tag="VXC24_001481"
     CDS             14772..15590
                     /locus_tag="VXC24_001481"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0493579.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15587..16483
                     /locus_tag="VXC24_001482"
     CDS             15587..16483
                     /locus_tag="VXC24_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0493580.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16527..17501
                     /gene="pta"
                     /locus_tag="VXC24_001483"
     CDS             16527..17501
                     /gene="pta"
                     /locus_tag="VXC24_001483"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0493581.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(17762..>18183)
                     /locus_tag="VXC24_001484"
     CDS             complement(17762..>18183)
                     /locus_tag="VXC24_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0493582.1"
                     /translation="SDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHF
                     QNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5394 a         3301 c         3997 g         5491 t
ORIGIN      
        1 gtagcggatt aaaatggtct ggggatagac cgttttaagt ctgacgctgg aaataagaat
       61 tgtcagaaga agggatagcg aaatcgtggc tctacgaaca ggaacgtgat aataaggcgt
      121 atatagcgga taagagggcc tcaaactcta aagtccaaaa aggtagtcgt aacctatatg
      181 cgtaaatcac gagagtaatt gaattcgtac taagattttc tattttcact gtaacctttt
      241 aacgtcctca tatcttgtat acacgaggaa agatgtacga cttatcccgt gaggtctatc
      301 actataaaga gaaaacgaca gatagaagtg atcctgagtc acggttatct ttaaaataga
      361 ttgtctgata ggatgctagc ctgaaaacgt cttgttcatg aaatatagga cggtatgtat
      421 aaaacgcttc tgtgaactga gagaaggggg agaagttctt gctaaaattt agttgaacag
      481 ccgtattccg atatttagat aagagatcta gtcttagctc ctactcggtt tcaggggata
      541 aaaaaggggc aatagcgatt cgagaaagat tatactcttc gaaaatctct tcaaatcacg
      601 tcaatatcgc cttgccgtac gtgtaggata ctgactacgt cagttccatc tacaacctca
      661 aaacagtgtt ttgagcaacc tgcggctagt ttcctagtgt gatctttgat ttttattgag
      721 tattagtaat tcagttacta actcgtcaac tctgatttat ccaataaaat tgaaaaggat
      781 ggaaaaaagg ataaatttat gatatacttt attttgaaga ccttattaga aatcttgaaa
      841 gagtattgaa aacttagaat gagaaaaatt gttatcaatg gtggattacc actgcaaggt
      901 gaaattacta ttagtggtgc taaaaatagt gttgtggcct taattccagc tattatattg
      961 gctgatgatg tggtgacttt ggattgtgtt ccagatattt cggatgtagc cagtcttgtc
     1021 gaaatcatgg aattgatggg agctactgtt aagcgttatg acgatgtctt ggagattgat
     1081 ccaagaggtg ttcaaaatat tccaatgcct tatggtaaaa ttaacagtct tcgtgcatct
     1141 tattattttt atgggagcct cttaggccgt tttggtgaag cgacagttgg tctaccggga
     1201 ggatgtgatc ttggtcctcg tccgattgac ttacacctta aggcgtttga agctatgggt
     1261 gccactgcta gctacgaggg agataacatg aagttatctg ctaaagatac aggacttcat
     1321 ggtgcaagta tttacatgga tacggttagt gtgggagcaa cgattaatac gatgattgct
     1381 gcggttaaag caaatggtcg tactattatt gaaaatgcag cccgtgaacc tgagattatt
     1441 gatgtagcta ctctcttgaa taatatgggt gcccatatcc gtggggcagg aactaatatc
     1501 atcattattg atggtgttga aagattacat gggacacgtc atcaggtgat tccagaccgc
     1561 attgaagctg gaacatatat atctttagct gctgcagttg gtaaaggaat tcgtataaat
     1621 aatgttcttt acgaacacct ggaagggttt attgctaagt tggaagaaat gggagtgaga
     1681 atgactgtat ctgaagacag catttttgtc gaggaacagt ctaatttgaa agcaatcaat
     1741 attaagacag ctccttaccc aggctttgca actgatttgc aacaaccgct tacccctctt
     1801 ttactaagag cgaatggtcg tggtacaatt gtcgatacga tttacgaaaa acgtgtaaat
     1861 catgtttttg aactagcaaa gatggatgcg gatatttcga caacaaatgg tcatattttg
     1921 tacacgggtg gacgtgattt acgtggggcc agtgttaaag cgaccgactt aagagctggg
     1981 gctgcactag tcattgctgg gcttatggct gaaggtaaaa ctgaaattac caatatcgag
     2041 tttatcttac gtggttattc tgatattatc gaaaaattac gtaatttagg agcggatatt
     2101 agacttgttg aggattaaac cgtagaggtg tttatgaata tttggaccaa attagcaatg
     2161 ttttcttttt ttgaaacgga tcgcttgtat ttgcgtcctt tcttttttag tgatagtcag
     2221 gacttccgcg agatagcttc aaatccagaa aatcttcaat ttattttccc aacgcaggca
     2281 agtctggaag aaagtcaata tgcactggcc aattacttta tgaagtcccc tttgggagtg
     2341 tgggcaattt gtgaccagaa aaatcaacaa atgattggtt ctattaaatt tgagaagtta
     2401 gatgaaatca aaaaagaagc tgagcttggc tattttttga gaaaagatgc ttggtcgcaa
     2461 ggatttatga cagaggttgt tagaaaaatt tgtcagcttt cttttgagga atttggctta
     2521 aaacaattat ctatcattac ccaccttgaa aatgaagcta gccaaagagt tgctcttaag
     2581 tctggattta gtttgttccg tcagtttaag ggaagtgatc gttacacaag aaaaatgcgg
     2641 gattatcttg aatttcggta tgtaaaagga gagttcaatg agtaagcatc aggaaattct
     2701 aagctatttg gaggaattac cagtaggtaa aagggtcagt gttcgtagca tttcgaatca
     2761 tctaggagtt agtgatggaa cagcctatcg ggctattaaa gaagctgaaa accgtggaat
     2821 tgtggagacc cgtcctagaa gtggaacaat tcgtgttaaa tcccagaaag ttgctataga
     2881 gagattaacg tttgctgaaa ttgcagaagt gacttcttct gaggttctgg ctgggcaaga
     2941 aggtttagag agagaattta gtaagttttc aattggtgcc atgactgaac aaaatatctt
     3001 gtcttacctt catgatgggg ggctcttgat tgtcggagac cgaacccgta ttcagttgct
     3061 agccttggaa aatgaaaatg cagttctggt tacaggggga tttcaggttc atgatgatgt
     3121 gcttaaactg gccaatcaaa aagggattcc tgttctaaga agtaagcatg atacctttac
     3181 cgtcgcgacc atgatcaata aagccttgtc aaatgtccaa atcaagactg atattctgac
     3241 agttgagaaa ctttatcgcc ctagtcatga gtatggtttt ctgagagaga cagatacagt
     3301 taaagattat ttggacttgg ttcgtaagaa tcgtagcagc cgtttccctg ttatcaatca
     3361 acatcaggtc gttgttggcg ttgtaaccat gagagacgct ggtgataaat caccaagcac
     3421 gacaattgat aaggttatgt ctcgtagtct atttttggtt ggattatcga caaatattgc
     3481 caatgtgagt caacggatga tcgcagaaga ctttgaaatg gtaccagttg ttcgaagcaa
     3541 tcaaactttg cttggcgttg tgacgcgacg agatgtcatg gagaagatga gccgttccca
     3601 agtttcggct ctaccaactt tttctgagca gattggacaa aagctctctt atcaccatga
     3661 tgaagtagtc attacagtgg aaccctttat gctagaaaaa aatggagttt tggctaatgg
     3721 tgtattggca gaaattctga cccacatgac ccaagattta gttgttaata gtggtcgcaa
     3781 tctcattatc gagcagatgc tgatctactt tttgcaggct gttcagatag atgatatatt
     3841 gcgcattcag gcacggatta ttcatcatac gagacggtca gctataattg attacgatat
     3901 ttatcatggt caccagattg tttcaaaagc aaatgtgact gttaaaatta attagaaact
     3961 aggagaaaag atgataacat taaaatcagc tcgtgaaatc gaagctatgg acaaggctgg
     4021 tgattttcta gcaagtattc atataggctt acgtgatttg attaagccag gcgtagatat
     4081 gtgggaagtt gaagaatatg tccgccgtcg ttgtaaagaa gaaaatttcc ttccacttca
     4141 gattggggtt gacggtgcca tgatggacta tccttatgct acctgttgct ctcttaacga
     4201 tgaagtggct cacgctttcc ctcgtcatta tatcttgaaa gatggtgatt tgctcaaagt
     4261 tgatatggtt ttgggaggtc ccattgctaa atctgacctg aatgtctcaa aattaaactt
     4321 caacaatgtt gaacaaatga aaaaatacac tcagagctat tctggtggtt tagcagactc
     4381 atgttgggct tatgctgttg gtacaccgtc cgaagaagtc aaaaacttga tggatgtaac
     4441 caaagaagct atgtacaagg gtattgagca agctgttatt ggaaatcgta tcggtgatat
     4501 cggtgcggct attcaagaat acgctgaaag tcgtggttac ggtgtagtgc gtgatttggt
     4561 tggtcatggt gttggcccaa ctatgcacga agaaccaatg gttcctaact atggtattgc
     4621 aggtcgtgga ctccgtcttc gtgaaggaat ggtcttaacc attgaaccaa tgatcaatac
     4681 aggcgattgg gaaattgata cagatatgaa aactggttgg gcgcataaga ccattgacgg
     4741 tggattgtca tgtcagtatg aacaccaatt tgtcattacg aaagatggac ctgttatctt
     4801 gactagccaa ggtgaagaag gaacttatta ataaaaagtg aaaagactac tggaagttta
     4861 ttatgaaaaa atccagtaga tcttttcata ataaaacgca ttgtatcaag tgttaggggc
     4921 tgatatcatg cgtttttctg cttttaagat tttttccaac tctgtttgta agcgcatcat
     4981 aacaaagggt ctaggattca gggctctcct cctatatact attagtaaag taaaactaag
     5041 ggaggatatt ttagtgtcgc agtctattgt tcctgtagag attccacaat attgtcgttt
     5101 tgattctaaa aagagaaatg gaattctgtt taatgttcgt attgccaatc ttaaatttac
     5161 cttttttaga ttagacttcc tgcgaaacaa aatatggtat agtagttcca tgaattatga
     5221 agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc agcgtaccac
     5281 ttttgaagag atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg
     5341 acgaaaacct aaattaagcc tagaagacct tcttatggcc actcttcaat atgtgcgaga
     5401 atatcgaact tatgaacaaa ttgcggctga ttttggtatt cacgaaagca acttactccg
     5461 tcggagccaa tgggttgaag taactcttgt tcaaagtggt tttacgattt caagaactcc
     5521 tctcagttct gaggacacgg taatgattga tgcgacggaa gtaaaaatca atcgccctaa
     5581 aaaaagaatt agcgaatgat tctggtaaaa agaaatgcca cgctatgaag gctcaagcga
     5641 ttgtcacaag tcaagggaga attgtttctt tggatatcgc tgtgaactat tgtcatgata
     5701 tgaagttgtt caaaatgagt cgcagaaata tcggacaagc tggaaaaatc ttggctgaca
     5761 gtggttatca agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca
     5821 aactcaagcc gctaacagtt gaagataaag cctataacca tgcgctatcc aaggatagaa
     5881 gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacttatc
     5941 gaaatcatcg taaacgtttc ggattacgaa tgaatttgag tgctggtatt atcaatcatg
     6001 aactaggatt ctagttttgc aggaagtcta ttgaggtatt gagctagttt atgaaaaaat
     6061 tgggtgaaaa agtcgagtgt tttagaaacc cacagtgtag tattctagtt tcaatccact
     6121 atattttgct actccccgta aagtttctat tttccctgat ttctgatata atagaaatat
     6181 tgacttcaag agtaaggaag agaagatgaa cgcattatta aatggaatga atgaccgtca
     6241 ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc atggcagggg ctggttctgg
     6301 aaagactcgt gttttgaccc accgtatcgc ttatttgatt gatgaaaagc tggtcaatcc
     6361 ttggaatatc ttggccatta cctttaccaa caaggctgcg cgtgagatga aagagcgtgc
     6421 ttatagcctc aatccagcga ctcaggactg tctgattgcg accttccact ccatgtgtgt
     6481 gcgtattttg cgtcgcgatg cggaccatat tggctacaat cgtaatttta caattgtgga
     6541 tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa cagttgaact tggatcctaa
     6601 aaaatggaat gaacgaacta ttttggggac catttccaat gctaagaatg atttgattga
     6661 tgatgttgct tatgctgccc aagctggcga tatgtatacg caaattgtgg cccagtgtta
     6721 tacagcctat caaaaagaac ttcgtcagtc tgaatccgtt gactttgatg atttgattat
     6781 gctgaccttg cgtctctttg atcaaaatcc tgatgttttg acctactacc agcaaaaatt
     6841 ccaatacatc cacgttgatg agtaccaaga taccaaccac gctcagtacc aattggtcaa
     6901 actcttggct tcccgtttta aaaatatctg tgtggttggg gatgcggacc agtctatcta
     6961 cggttggcgt ggtgctgata tgcagaatat cttggacttt gaaaaggatt accccaaagc
     7021 caaggttgtt ttgttggagg aaaattaccg ctcaaccaaa accattctcc aagcggccaa
     7081 cgaggttatt aaaaataata aaaatcgccg tcctaaaaat ctctggactc aaaacgctga
     7141 tggggagcaa atcgtttact atcgtgccga tgatgagctg gatgaggctg tatttgtagc
     7201 cagaaccatc gatgaactta gtcgcagtca aaacttcctt cataaggatt ttgcagttct
     7261 ctatcggact aatgcccagt cccgtacaat tgaggaagcc ctgctcaagt ctaacattcc
     7321 ttataccatg gttggcggaa ccaaattcta cagccgtaag gaaattcgcg atattattgc
     7381 ttatctcaac cttattgcta atttgagtga caatattagt tttgagcgta ttatcaacga
     7441 gcctaaacgt ggaattggtc taggtacagt tgagaaaatc cgtgattttg caaatttgca
     7501 aaatatgtct atgctggatg cttctgctaa tattatgttg tctggtatca agggtaaggc
     7561 agcccaatct atctgggatt ttgccaatat gatgcttgat ttgcgggagc agctagacca
     7621 cttaagcatt acagagttgg ttgagtccgt cctagaaaaa acaggttatg tcgatattct
     7681 taacgcccaa gcgactctag aaagcaaggc acgggttgaa aatatcgaag agtttctttc
     7741 tgttacgaag aactttgatg acaccactga tgtgacagaa gaggaaactg gtctggacaa
     7801 actgagtcgt ttcttaaatg acttggcttt gattgccgac acagattcag gtagtcagga
     7861 gacatcagaa gtgaccttga tgaccctgca tgctgccaaa ggtctcgaat ttccagttgt
     7921 ctttttgatt gggatggaag aaaatgtctt tccacttagt cgtgcgactg aagatccaga
     7981 tgaattagaa gaagagcgcc gtctagccta tgtaggtatc acgcgtgcag agaaaattct
     8041 ctatctgacc aatgccaact cacgcttgct ttttggtcgt accaattata accgtccgac
     8101 tcgttttatt aacgaaatca gttcagactt gcttgagtat caaggtctgg ctcgtcctgc
     8161 aaatacaagc tttaaggcat catatagcag tggtagtatt tcctttggtc aaggtatgag
     8221 tttggctcag gctcttcaag accgtaaacg cggtgctgcc ccaaaatcaa tccagtcaag
     8281 cggtcttcca tttggtcaat ttacagctgg cgcaaaatca gcatctagcg aggcaaattg
     8341 gtccattggt gacattgctc tccacaagaa atggggagag ggaactgttc tggaagtttc
     8401 aggtagcggt gctaggcagg aattgaaaat caatttccca gaagtaggtt tgaaaaaact
     8461 tttagccagt gtggctccaa ttgagaaaaa aatctaattt tccatccttc tcacgaataa
     8521 taaagtgagg aggattttta tgtacagtat ttcattccaa gaagattcac tattaccaag
     8581 agaaaggctg gccaaggaag gagttgaagc gcttagtaac caagagttgc tagctatttt
     8641 actcaggaca ggaacacgtc aagctagcgt ttttgaaatt gcccaaaaag tcttgaacaa
     8701 tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag gaattgcaga gtttgtctgg
     8761 tattgggcgt gttaaggcca tagaattaca agctatgatt gaactggggc atcgtattca
     8821 caaacacgag actcttgaaa tggaaagtat tctcagcagt caaaagttgg ccaagaagat
     8881 gcagcaggaa ttaggggata aaaaacaaga gcacctggtg gcactctatc tcaatactca
     8941 aaatcaaatc atccatcagc agaccatttt tatcggttct gtaactcgta gtatcgctga
     9001 accgcgagag attctgcact atgcaatcaa gcatatggcg acttctctta tcttggtcca
     9061 caatcatcct tcaggagcgg tagcgcctag ccaaaatgat gatcatgtca ctaaacttgt
     9121 taaagaagcc tgcgaattga tggggattgt tctcttggac catttgattg tctctcattc
     9181 taattacttt agttatcgtg aaaagacaga tttaatctaa agttcattaa cgacatagtc
     9241 aaagagtttt ttatctttgg gacgattttc aaaaagaagt tctggatgcc attggacacc
     9301 gagaaaggcg acatcatccg tactcatgac agcctcaatg ataccatctt taggatcatg
     9361 agccacaact tttaaatttg gtgctaagtc cttgatgctc tggtggtgga aggagttgat
     9421 atgagagatt tctccataga tttcttggag aacggtatct ggttctgtta ccaagcgttg
     9481 agttgtgtac tcaacagaag aatcctgcca atggtcttcg atatcttggt acaaagttcc
     9541 acccatggca acgttaaaga gttgggtacc acggcagaca gagaaaatgg gctttttctg
     9601 tttaatagct tccttgatga gggtcagttc gaagatatct ctttgaaggt gatagtcatc
     9661 gctatcaatg gttttgggtt cgccataaaa ttttggatcg acattttgcc cacctgtcaa
     9721 gatgagcttg tcaatcaaac tgatatagtg gcaggccatt tcttgatcac caatcggtag
     9781 gatgatggga atccctccag aatctttaac gccttcaaca aagccttttg ctgcgtagct
     9841 catcatgatg tcatcatctg gatgagcttt ttcgtttcct gtaatcccaa taactggttt
     9901 tttcataaaa tgattttcgc tttctaatcc tcttttcgca tgaagtagag gagggtttgg
     9961 agttcacttg tcaaatcgac atactgaacg accacgtctt ttggtaaatg cagatggact
    10021 ggtgaaaaac tgagaattcc tttcacacca gcatcaacca agagattagc aacctcttgt
    10081 gacttgacgc tgggaacagt taggatagca gtcttcacat cagcatcctt gattttatcc
    10141 ttgatctgag aaatcccgta aatgggaatc ccgtcaggag tttgggtacc gacttcagga
    10201 tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt tacgttcgtg gaagcggtag
    10261 tggagaaggg catggcccat atttccaata ccaaccagca tgacattggt aatagagttg
    10321 tcattgagca aatcggcaaa aaatgtcatt agttttttga catcatagcc aaaaccacga
    10381 cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg tcgctgaatc aataccgata
    10441 gcctctgcaa tttgcttaga gttggcacgt tcaatctttt ctgcatgaaa tctcttaaaa
    10501 attcgatagt agagagagag tctttttgct gtagcttttg gaatagcaaa ctgtttatct
    10561 ttcacaaaat cacaaccttt ctattcttct attttataga aacattgtga aaaaatcaac
    10621 aaaaataaga aaaaactaag aaaaatctta gttttgatgt aaaaaatctg catgagatag
    10681 aaaacggtag aggtctccga ccagaccctg ataaactttt tggcccctaa aagtcagaga
    10741 agtcacataa agtgtatctg gtaaggttac acatcctgac aaagtcaaca tgagagcctc
    10801 atgatcctca tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa
    10861 cattttggct ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga
    10921 ggaagtagaa tttttcctga tgaatatggt ggtcttctga tttgaaaata tcaactagac
    10981 gaaggccaaa cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga
    11041 ttttgagttg gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat
    11101 agttaccaac cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag
    11161 ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat
    11221 ggctaacctc cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta
    11281 ttttgtggcg acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac
    11341 atggcttcaa gaacatggct ggattggaca acgcctgcag tacaggctga gccagtagag
    11401 attgaaattc cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat
    11461 ccaatattga gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaatgccc
    11521 tccagctctg ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt
    11581 ttttctaggt cttcttttag ggctgcaacc atgcctacga tagcaggcag attttcagtt
    11641 cctgcacgtt ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta
    11701 gatgcgtaga gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga
    11761 aaatcaatgc ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca
    11821 acatgatagg cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg
    11881 tttcctgtct cattattggc aaacatggta gaaaccaaaa tcgtatcgtc acgtaaagcc
    11941 ttttgaattt gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac
    12001 ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt
    12061 gtgatgatat gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta
    12121 ttgccttcag tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg
    12181 gctagttcct gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata
    12241 ctagaaggat ttccgtgggt ttcttgcata accttggtca tagctgaaat agcaactgct
    12301 gacataggag tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta
    12361 ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca
    12421 attaactcac tagcagtgat gtagcataca tttttaggag ttttttcttt tgttgctact
    12481 gaatcagtca caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg
    12541 acgaagagac cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt
    12601 ttagaagctt cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc
    12661 ttaccttcaa catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag
    12721 tcgataatgg cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct
    12781 gaatttttag ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt
    12841 tttgcgaata ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc
    12901 tgaacggcat gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg
    12961 gcaactagtt ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag
    13021 ccaaaatatg gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc
    13081 atgattaaca attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa
    13141 acatcataac cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga
    13201 cgtgatgata gttttccaag tggggcacca acagcttggg caattttttg tgcaatctct
    13261 tggttagagt tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct
    13321 ctgtaaactt tataaatcct agttatattt accttacata tatgaactgg gatttgtgta
    13381 tttttatctt ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt
    13441 gacaaatcga accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa
    13501 ttgtcggaaa tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc
    13561 tgttatatca aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc
    13621 atagcgaagc gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt
    13681 cgccaattca tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc
    13741 atcttttagt tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag
    13801 tgtcaactca gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag
    13861 ttcaaaatca ggcgtgtcga tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa
    13921 ctggtctttt agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa
    13981 atgtttcatt tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat
    14041 tgtatttatt gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga
    14101 gaacaaggga gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc
    14161 tgttggtgag ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa
    14221 gcattctcca attgagtttg tgaccggtcg agtcaagcca attgagagca tcaaagaaaa
    14281 aatggctcgt cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg
    14341 cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa
    14401 gcgtcaggat atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg
    14461 ctatcgttcc tatcatgtgg tagtagaata tacggttgat accatcaatg gagctaagac
    14521 tattttggca gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca
    14581 ttctctcaac tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat
    14641 tacagctaga atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca
    14701 agaagcccag gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag
    14761 tgacgataca gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc
    14821 agagtcaaag ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca
    14881 atgataccaa tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct
    14941 ttcataagta cgaaaatcag cttgacaagg tccgctttat cggtcttcat actggacatt
    15001 tgggcttcta tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc
    15061 tagatactgg ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt ctcgaaaatg
    15121 gtgaagttaa gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca
    15181 tggtggcaga tattgtaata aatggtgttc cctttgaacg ttttcgtgga gacgggctaa
    15241 cagtttcgac accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac
    15301 accctaccat tgaagctttg caattaacgg agattgccag ccttaataat cgtgtctatc
    15361 gaacactggg ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa
    15421 gaaacgatta tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc
    15481 gtattgagta tcaaatcgac catcataaga ttcactttgt cgcgactcct agccatacca
    15541 gtttttggaa ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt
    15601 tatcgcagat gaacatgtca aggttaagac ctttttaaaa aagcacgagg tttctaaggg
    15661 attgctggcc aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa
    15721 tgcaacgtat ctattggacg ttggagacta cgttaccatt gacattcccg ctgaggaagg
    15781 ctttgaaacc ttggaggcta ttgagcatct attagatatt ctctatgagg atgatcactt
    15841 tctagtcttg aataaaccct atggagtggc ttctattcct agtgtcaatc actctaatac
    15901 cattgccaat tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca
    15961 cattgttacc agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta
    16021 tgcccatgca cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc
    16081 tttggttaag ggagatggac atttggagcc agaaggggaa attattgctc cgattgcgcg
    16141 tgatgaagat tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc
    16201 atacaagatt gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg
    16261 tcgaacccat caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga
    16321 tttgtatggt ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct
    16381 atccttttat catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga
    16441 tttcagtaac cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat
    16501 aattattatc ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg
    16561 ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa
    16621 caaaacgctt agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa
    16681 ttaaaattta tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac
    16741 attatcctca atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga
    16801 ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg
    16861 tttacttggg cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag
    16921 ttcgtccagc tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct
    16981 tcctcatggt tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aacatcaatc
    17041 cagatgcaga agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg
    17101 gcatcgaacc taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa
    17161 gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa
    17221 tcgatggtga gttgcaattt gatgcagcct ttgttcctga aactgcagct ctgaaagctc
    17281 ctggaagtac ggtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa
    17341 atatcggtta caagatggct gaacgcctag gtggctttgc ggctgtagga cctgttttgc
    17401 aaggtttaaa caagccagtt aatgatcttt ctcgtggatg taatgcagat gatgtttaca
    17461 agttgaccct catcacagca gctcaagcag ttcatcaata gtgaaaacta taaagcgata
    17521 tactatgcta tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag
    17581 aactaaatta ctgattggtg tcaaaaagga aaacttccaa gcgataatat cctgtctata
    17641 cacgacctat agaaatctgt aatatacatg tccgtaaaac gataaattcc ctttttgatt
    17701 ttaaatgagt atgaaaagag aattttttgg ctctttgtca actgtagtgg gttgaagtca
    17761 gctaagctcg agaaaggaca aattttgtcc tttctttttt gatattcaga gcgataaaaa
    17821 tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgcgtttg ataagtttga
    17881 tgagattatt ggtcgcttcc aatttggcgt ttgaataggg tagttgaagg gcgttgacga
    17941 ttttctcttt gtcctttaga aaggttttaa agacagtctg aaaaagagga tgaacctgct
    18001 ttagattgtc ctcaataagc ccgaaaaatt tctcagggtc tttgttctga aagtgaaaca
    18061 gcaagagttg atagagctga tagtgatgtt tcaagtcttg tgaatagctc aaaagcttgt
    18121 caagaatttc tttatttgtt aagtgcatgc gaaaagtagg gcgataaaaa cgtttatcgc
    18181 tca
//
LOCUS       DAVLBN010000043        18040 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLBN010000043 DAVLBN010000000
VERSION     DAVLBN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.043"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            232..2361
                     /locus_tag="VXC24_001485"
     CDS             232..2361
                     /locus_tag="VXC24_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0493583.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            2348..2797
                     /locus_tag="VXC24_001486"
     CDS             2348..2797
                     /locus_tag="VXC24_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0493584.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            2855..3127
                     /locus_tag="VXC24_001487"
     CDS             2855..3127
                     /locus_tag="VXC24_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0493585.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(3481..3672)
                     /locus_tag="VXC24_001488"
     CDS             complement(3481..3672)
                     /locus_tag="VXC24_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493586.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            4100..4858
                     /locus_tag="VXC24_001489"
     CDS             4100..4858
                     /locus_tag="VXC24_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493587.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4860..6848
                     /locus_tag="VXC24_001490"
     CDS             4860..6848
                     /locus_tag="VXC24_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493588.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(6890..7534)
                     /locus_tag="VXC24_001491"
     CDS             complement(6890..7534)
                     /locus_tag="VXC24_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0493589.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(7560..8555)
                     /locus_tag="VXC24_001492"
     CDS             complement(7560..8555)
                     /locus_tag="VXC24_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0493590.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            9262..10737
                     /locus_tag="VXC24_001493"
     CDS             9262..10737
                     /locus_tag="VXC24_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0493591.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(10703..11418)
                     /locus_tag="VXC24_001494"
                     /pseudo
     CDS             complement(10703..11418)
                     /locus_tag="VXC24_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            11505..11642
                     /locus_tag="VXC24_001495"
     CDS             11505..11642
                     /locus_tag="VXC24_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493592.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            11673..12533
                     /gene="speE"
                     /locus_tag="VXC24_001496"
     CDS             11673..12533
                     /gene="speE"
                     /locus_tag="VXC24_001496"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0493593.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            12530..13789
                     /locus_tag="VXC24_001497"
     CDS             12530..13789
                     /locus_tag="VXC24_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0493594.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            13789..14916
                     /gene="nspC"
                     /locus_tag="VXC24_001498"
     CDS             13789..14916
                     /gene="nspC"
                     /locus_tag="VXC24_001498"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0493595.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            14913..15998
                     /gene="aguA"
                     /locus_tag="VXC24_001499"
     CDS             14913..15998
                     /gene="aguA"
                     /locus_tag="VXC24_001499"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0493596.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            16008..16883
                     /gene="aguB"
                     /locus_tag="VXC24_001500"
     CDS             16008..16883
                     /gene="aguB"
                     /locus_tag="VXC24_001500"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0493597.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(17064..17873)
                     /locus_tag="VXC24_001501"
     CDS             complement(17064..17873)
                     /locus_tag="VXC24_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0493598.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
BASE COUNT         5285 a         3486 c         3902 g         5367 t
ORIGIN      
        1 atataaaaat ttgaaaagtc aatgtgttat tccaggtcag gaacatcttc cagaactggc
       61 tattatgtct gatccattaa atacttttga tatcatggct tggttaaaaa aaggtggcaa
      121 tgctctttaa gtgcaagtta ttgcgctgta gcatataaat ctatttccta catatttttt
      181 aaatgttcta cgagttaatt tgaaacgttt agcttgtggt ataatagatt tatggataaa
      241 aaatatgaaa aaatctctca ggatttggga gtgacgttaa agcaaattga taccgttcta
      301 agtttgacag ctgaaggggc gactattccc tttatcgcgc gttatcgcaa ggacatgact
      361 ggtagtctgg atgaggtggc gattaaggct attattgatt tggataaaag tctgacaaat
      421 ctcaatgacc gtaaggaagc tgtcttagct aagattcaag aacaaggtaa gttgaccaag
      481 gaattggaag aagctatctt agttgccgaa aaattagcag acgttgaaga actctatctt
      541 ccttataagg aaaagcgtcg taccaaggca accattgccc gtgaagctgg actctttcct
      601 cttgctcgtt tgattttgca gaatatagtt gacttagaga aagaagctga aaagttcgtc
      661 tgtgaaggat ttgcgactgg caaggaagcc ttgaccggtg cagttgatat tttggtcgaa
      721 gccttatcgg aagatgtgac cttgcgttct atgacttatc aggaagtgct gagacactct
      781 aaactcactt ctcaagccaa ggatgaaagt cttgatgaaa agcaggtttt tcagatttat
      841 tatgattttt cagagacagt tggaactatg caaggctatc gtaccttggc tctcaatcgt
      901 ggggagaaac ttggtgtctt gaagatcggt tttgaacatg cgacggaccg tattcttgcc
      961 ttctttgcta ctcgtttcaa ggtgaaaaat gcttatattg atgaagttgt tcagcaatcc
     1021 gttaagaaaa aggtcttgcc tgctattgag cgtcgtattc ggacagaatt aactgagaaa
     1081 gctgaagagg gagctatcca acttttttct gacaatctgc gcaatctcct cttggttgct
     1141 ccactgaaag ggcgcgtggt tcttgggttt gacccagcct ttcgtacagg tgccaagcta
     1201 gctgtcgtgg atgcaacagg aaaaatgctg acaactcagg ttatttatcc tgttaaacca
     1261 gcatcagctc gtcaaatcga agaagccaag aaagatttag cagatttaat tggtcaatac
     1321 ggtgtagaga ttattgccat tggaaatgga acggccagtc gtgaaagtga agcttttgta
     1381 gcggaagttc tgaaagattt ccctgaagtc agctatgtta tcgttaatga aagtggtgct
     1441 tctgtctatt ctgccagcga acttgctcgt caggagtttc cagacttgac cgttgaaaaa
     1501 cgctctgcca tttctatcgc ccgtcgtttg caagatcctc ttgcggaatt ggtcaaaatc
     1561 gatcctaagt caattggtgt cggtcaatac caacacgatg tcagtcagaa gaaactatct
     1621 gagagtctgg actttgttgt cgatacagtg gttaaccaag ttggtgtcaa tgtcaataca
     1681 gctagcccag ctcttctttc acacgtagct ggactcaata aaaccatttc tgaaaatatc
     1741 gtcaaatacc gtgaggaaga gggaaaaatc acttcacgct cccaaatcaa gaaagttcct
     1801 cgtttggggg ccaaggcttt tgaacaggct gctggtttcc tccgtatccc tgaaagtagc
     1861 aatatccttg ataatacagg agttcaccca gaaaattacg ctgccgttaa ggaactcttc
     1921 aaatgcttgg acattaagga tctgaatgaa gaggcccaaa gtaaactcaa gtcgctttca
     1981 gtcaaggaaa tggcgcaaga gttagacctt ggtccagaaa ctcttaaaga tatcattgca
     2041 gatcttctca aaccaggtcg agatttccgt gattcctttg atgctccagt tctccgtcaa
     2101 gatgtcctag atatcaagga cttagtggtt ggacaaaagc tagaaggagt ggtgcgtaat
     2161 gttgttgatt tcggtgcttt tgttgatatc ggaattcatg aggacggtct catccatatt
     2221 tcccatatga gtcgcaagtt tatcaaacac cctagtcaag tggtggcagt tggagatttg
     2281 gtgagcgttt gggttaagaa aattgatact gaacgtgaaa aagttaatct gtctctccta
     2341 gctccaaatg aaactgactg attacgtcaa gcaggtttca ctagaagact tcggcagacc
     2401 ttttatccat catgtccagt ggaataggcg tctacgttcg acaggtgggc gatttttccc
     2461 caaagatggg catttggatt ttaatcccaa ggtttatcag gaactggggt tggacgtttt
     2521 taggaaaatt gtccgacatg aactctgtca ttatcacctc tattttcaag ggaaaggcta
     2581 tcaacacaag gatcgggatt ttaaggaact gttgaaagca gtggatggat tacggtttgt
     2641 accatccttg cccaatagta actccaagcc aatcaagctc tatcgttgcc aatcctgcca
     2701 gcaaacttat cagcgtaagc gtaggattga tacccaacgc tatcgctgtg gactttgtcg
     2761 aggaaagttg ctattagtaa atcagcctga ggactgatga aagccgagcc tatccgtgat
     2821 atactagtct aacctagcag aaagaggaaa tatcatgaac agtaagtttt ataaaatgag
     2881 acgaaatcgc atgatttcag gagttttagc aggtctgtca gacaagtgga actttgatgt
     2941 tacccttgta cgttttctgt ttgccatttt tacagtcgca aactttggac ttggggtgat
     3001 tatctatatc atcctagctt ctatcatgcc aaccaaggaa gaaatcgaag cagaaatgta
     3061 cggaacaggc ccacgtaaac gcaaagaagc tcaagccatt gacgataatg aaggctggtt
     3121 ttggtgaggt tttacaaaag atttggaata cgcaaaaagc tttaaatcaa tagtctaaac
     3181 tgcttgattt aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa
     3241 gccagccgca ggctgtaatt tagtcggcaa tgtgaagttg atatagtttg cactttgatt
     3301 tttgaatagt attaataata tttcgccagc ttcatccaca aactatagtg gattggaact
     3361 agaataggac acctatactt ctaaaaaatt gttagaaatc gatttgactg tcctgatcga
     3421 tttgtcctgt tcttatttca ttttactata aaagcagtaa tttaaacgca gttttttaat
     3481 ctatttttgc tgttgagaca atacattttt ggaaaaatgg tggatgctga taacaactga
     3541 taaccagcaa ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc
     3601 aactaagagc tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc
     3661 tttgtgtttc attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa
     3721 attgaatggt atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt
     3781 caaagtaagc cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt
     3841 tctaagtaat tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt
     3901 ttgtaaggtt aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac
     3961 aaaggagtaa catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag
     4021 aaattgagcg cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat
     4081 attaagaaag gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa
     4141 aacacgtttt cagggcaacc aagtagaagc cctcaaggat attcacttta ccgtcgaaaa
     4201 gggtgactac gttgccatca tgggtgagtc tggttctggt aaatcaactc ttctcaatat
     4261 tctagctatg ctggataaac caagtcgtgg tcaggtttac ttgaatggaa ctgacaccgc
     4321 aaccattaaa aattcacagg cctctagctt ccgtcgtgaa aagttgggct ttgtcttcca
     4381 agactttaac ttgctagata ctctatctgt aaaggacaat atcttgcttc cgcttgtctt
     4441 gtcaagaaga cctattacag agatgatgaa gaaattggtg gtgacagctg agaatctggg
     4501 aataaaccaa ttacaagaga agtaccctta cgagatttct ggtggtcaga aacagcgtgt
     4561 agcagtagcc cgcgccatca tcacagaacc tgaaattctc cttgcggacg aaccgacagg
     4621 agctcttgac tccaagtcat ctgcagcctt acttgatgtc tttgatgaaa tcaatgagcg
     4681 cggccaaacc attctcatgg taacccactc aacagcagca gctagcagag ctaaacgtgt
     4741 actctttatc aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg
     4801 tcagatgttc caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta
     4861 tgtttcgatt aaccaataag ttagcggtat cgaacttgat taaaaaccgc aaactctact
     4921 atccttttgc gctggctgtt ctcttggcag tcactgtcac ctatctcttt tactctctaa
     4981 ccttcaatcc taagattgcg gaaatccgtg gaggaacaac cattcaggct acacttggat
     5041 ttggtatgtt tgtcgtcacc cttgcgtcag ccattatcgt tctctatgcc aatagttttg
     5101 tcatgaagaa ccgttccaag gaactaggaa tttatggcat gttgggcttg gagaagcgtc
     5161 atcttatcag tatgaccttt aaggagttag tggtatttgg gattctaact gttggagcgg
     5221 gtatcggtat tggagccttg tttgacaagt tgattttcgc tttcctactc aaactgatga
     5281 aattgaaggt ggaactggtc gctaccttcc agatgaaagt tgtcattaca gtacttcttg
     5341 tcttcggttt gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga
     5401 atgccctcca gctctcacgt gagaaagcta gcggagagaa aaaaggtcgc ttccttcctc
     5461 tccaaactat tcttggttcc ataagtttag ggattggata ttatcttgcc cttacggtaa
     5521 aagatcctct tacagcctta acaaccttct tcatagctgt tttactggtt atctttggta
     5581 cttatctttt gttcaatgca gggattaccg ttttccttca aatcttaaag aaaaataaga
     5641 aatactatta ccaacctaat aatctcatat ctgtttctaa cttgattttc cgtatgaaga
     5701 aaaatgcagt tggactagca actatcgcta ttttgtcaac aatggttttg gtaaccatgt
     5761 cagcagcgac aagcattttc aattccgcag aatcctttaa aaaagttcta aatcctcatg
     5821 attttggggt ttcagggcaa aatgttgaaa aagaagattt ggacaaactc ttgagccagt
     5881 ttgcaagtga caaaggttat aagattaaag agaaagaagt gcttcgttac agtaactttg
     5941 gtattgcaaa tcaagaagga accaagttaa ctatttttga aaaaggacaa aaccgtgtcc
     6001 aaccaaaaac agttttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa
     6061 aactgtctct atcaggaaat gaggtcggtc tctttgccaa aaatgacgga ctgaaaggac
     6121 agaaagctct aactctaaat gatcatcaat tttctgtcaa agaagaattt aataaagatt
     6181 tcattgtcaa ccatgttcca aataagttta atatcttgac tactgattac aattaccttg
     6241 ttgttcctga tttacaagcc tttttggatc aattcccaga ttcggctatc tataatcagt
     6301 tttacggtgg tatgaatgta gatgccagcg aagaagaaca actcaaggtc gctgaggagt
     6361 atgaaaacta cctcaatcaa tttaatgctc aattagacac agaaggtagc tatgtttatg
     6421 gtagcactct agcagatgct agtgctcaga tgagtgccct ctttggtggt gtcttcttta
     6481 tcggtatttt cctatccatt atctttatgg tcggaactgt tctggtcatc tactacaaac
     6541 aaatttctga aggctacgaa gaccgtgaac gctttattat cttgcagaaa gtcggtttgg
     6601 accaaaagca aatcaagcaa accatcaaca aacaggtttt aactgttttc ttccttcctt
     6661 tgctctttgc cttcctacat ctagcctttg cctaccatat gcttagcctg attttaaaag
     6721 tgattggtgt actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct
     6781 tcctcatcgc ctatgtgctg atttttatga ttacttcaag aagttatcgc aagattgtgc
     6841 aaatgtaaaa aagatacctc gacttcaaaa tcgaggtatt tcttgtattc taaatgctga
     6901 aaagttgttc gagcaggaag gtaactccca tggtcaagag accaatagca aggttccgaa
     6961 tcatagctgt tttggttggg gcttttccaa gtctagcact tgtgtaacca gtgagaagaa
     7021 gggccacacc gacaataagg acggtagcag ggatgcggta atcacttgga aaaatggtca
     7081 ctgacagcat tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt
     7141 gccaaggatt ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga
     7201 gtggattttt aagaaagatc ttattagtca agagttgggc agaagttttg aattctccat
     7261 tttggatata agaagcatag agggattttt tggctagttc cctatcttgg tctagcaaga
     7321 gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt
     7381 ctccaccagc cattgaaaag gcaccagcta agatagccgc aaaacctgat aaaaagataa
     7441 tccagatatt gctcgtggca ctggcaactc cgataaccac accagcaatg gaaataattc
     7501 catcgttagc atcaagaaca cccgcacgca ggatatttaa acgacctgca aaatttgaat
     7561 caatttcgtg atttgtttct gacgctaaat ttcaagttca agttagccat ccagaagtct
     7621 tctctgggtg acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg
     7681 aatgcgactt ctttgggagt cattttcttg attcccttag gtaaccatct acgaatgagc
     7741 ctgttgtgat tctcattagt tcccctttcc caagaggcat aggggtgcgc ataatagatg
     7801 tgctcctcag aaaatacatc aaacaagcga ttgaattccg ttccattatc tgccgtgatg
     7861 gaaagaatct tgtgttgttt taagatgagt tttagagcct gattgaccac atcagcactt
     7921 ttatttggaa tcaatcggat gatctgatgt ctactctttc gatccgtcaa gacaagcaaa
     7981 cagtagtttt tcgctctcgt aagtagaacc gtatcaatct cataatgccc attctccaag
     8041 cgaagattga tagcttcaga ccgctgttcg atggattgac cagcagattt aaagttggtg
     8101 ctagcctgtt tcttaagcgc ttttcctttt ctagggtaaa gcagatcctg tttgcttaac
     8161 cccaattttc catgatgaat ccaatagtaa atggttgaaa ttcccacgtt aaccccttta
     8221 accatcacca tcatttcagg cgaaaatttt tggttatgat agtggagaat cttttccttt
     8281 agttccttgg tcacgcttga tttcctgacc gagcgcttgc gattgttttc ataagactgt
     8341 tgagcatagt cggcagaata aacctctttg aagcgccctt ttccaagaca ttgtcggact
     8401 gtcccacgct tgatttcagt gtggatagtt tgaggaactt ttccaagcag agaggcaatt
     8461 tctctatttg atttcccttc ttttttccat ctttcgatta agcgacggct atcgattgtc
     8521 aaatgtttgg cttttgtagt ataattgtct tgcatctctg tgcctttctt gtgtttgtgg
     8581 ttgaacaaca agtataacac agaggtgttt tcttatgcct acaagagcta tcagctagtt
     8641 gaaccatcta atttttagga gggctgggtg gctaacttca ttatagaact ttcatttacg
     8701 aacatatagt aaaatgaaac aagaacagaa caaatcgatc aggacagtaa aatctatttc
     8761 taataatgtt ttagaagcag aagtgtacta ttctagtttc aatctactat atttttgttt
     8821 tttatcaaaa aatactttac aagttcttaa aaacatgata tagtaataaa gcttagaaaa
     8881 tgagatgatg ttttctagca aatataaacc cgagtaaaaa atgcctacgg acaggcaggg
     8941 ttgaatgccg aagcgtggtt gaaaagccac attattgata gggttaaaag cctactttta
     9001 taagttgatg ttaggacact tgtcctaatt cataaatttt tagtgtggtg aaagcacacg
     9061 tcatcttgtg aaacgatcaa taaagtacgt aatatttgct actagagagt taggaaacat
     9121 cgggaacaga catactcaac agaaaccaaa ataaacacgt cagaagattg cagagcaggt
     9181 gaaaacctgc tcttttttca tgagtcaacc tttagttcct tagttttcat aaggtcctaa
     9241 aaatattgaa aggagtatgt tttgaaagag ttagatcaaa accaagcccc aatttatgaa
     9301 gccttggtga agttacgcaa gaaaaggatt gttccctttg atgttccagg tcacaagcgt
     9361 ggacggggaa atccagaact tgtcgaactc ttaggagaaa aatgtgtagg cattgatgtc
     9421 aattcgatga aacccttgga taatttaggc catcctattt cgattattcg tgatgcagag
     9481 gagctggctg cagatgcttt tggagctagc catgcctttc taatgattgg tggaacaact
     9541 tcatcggtgc agactatgat tctggcaacc tgcaaggcag gagataagat tattctgcca
     9601 cgaaatgtcc ataaatctgc tatcaatgcg ttggttctat gtggtgccat tcccatctat
     9661 atcgagatga gtgtagatcc taagattggt atcgctttag gtcttgaaaa tgaccgagta
     9721 gcacaggcca taaaggacca tccagatgct aaggctatcc taatcaacaa tcctacttac
     9781 tacggcatct gttcagacct aaaggggttg acagaaatgg ctcatgaagc tggcatgatg
     9841 gttttagtag atgaagccca tggagcgcat ttgcatttca ctggtaaact tccaatttct
     9901 gctatggatg caggagctga tatggcagca gtttccatgc ataagtctgg tgggagtttg
     9961 acacaaagtt cgcttctttt aatcggggag cagatgaatc ccgagtacgt tcgtcagatt
    10021 ataaacctga cccagtctac atctgcctct tacttattga tggctagttt ggatatttca
    10081 cgtcgcaact tggcccttcg tggtaaagag tcgtttgagg aagtcattga gctatccgag
    10141 tacgctcgtc atgaaatcaa tgccattggc ggttactatg cttactcaaa agagttaata
    10201 gatggtgtgt cggtctgtga ttttgatgta accaagttgt cagtttacac tcagggaata
    10261 ggcttaacag gtatcgaggt ttatgacctc ttgcgagacg aatacgacat tcagatcgag
    10321 tttggtgata tcggcaatat cttggcctat atttccatcg gcgaccgcat ccaagacatc
    10381 gagcgcttgg ttggtgctct ggctgatatt aagagactct attcacgaga tgggaaggac
    10441 ttaatagctg gagaatatat tcagcccgag ttggtgctgt ctccacaaga agccttctat
    10501 tcagagagaa aaagtttgac cttagatgag tctgttggac aggtctgtgg agaatttgtc
    10561 atgtgctatc ctccagggat tcctatcttg gctcctggtg aacgcattac acgagaaatt
    10621 gtagactata tccaattcgc caaggaacgt ggttgctccc tccaagggac ggaagatcca
    10681 gaggtcaatc atatcaacgt tattaagaga aagacaaact ataagaaaag tcaatagttt
    10741 tatctaaact atttcttatt tcaatttgat gatttggcga tgattttaga gcacggcaaa
    10801 aagcccttga attagaagcg gtcaatcgct taatttctat cagcttatca aatcctgcct
    10861 caatcctttt ctgaggatta gggtagcgtg tcaagagttg gtaggtatat tctgaatgct
    10921 ttccaacgat tttatccaac tcaggaaaga tgatatcaag acaacgagtg tattgtactt
    10981 tccaatcaga ctgtttttct tgagacgatg aatatgtcta gccagtattt ttagttctac
    11041 ttgccgatta tcgtgttgaa attgttcacg attggggtca gaaagaagtt taagagcgat
    11101 gccatgagcg tctttcttat ccgttttagt cttgcgaagt gataatgatt tggcaaattc
    11161 cttgatgagc aaaggattgt aggtgtaaac tttatatcct tgttcatgca ggaagttcag
    11221 tagattaaag gcataatgtc cagtatcttc aagagcgatg agacagtctt ggttgagctg
    11281 tcgaagagac agatctaaga gttcaaaacc agctttatta tttgaaaaag tgagtggttt
    11341 aagaacagtt tttccttgaa cattcaaggc tgtaacatcg tgtttatttt tagcgatatc
    11401 aatgcccaca taaagcatgg gagtacctcc agatgtagta tttcaagtct acttggttat
    11461 ccacgaactt tttgccttgt taccttagac gagataaaac gtctatgcgt tatcaaactc
    11521 attaccaatt gaaacaaaag ctgtggttag agcctttcgg aaatcgtcaa gcgattggag
    11581 gaaatgaact aatccacagt ggcttattcc aagtatacca cttgggcttt ggcagtagct
    11641 aactgcgcta aatataatat aaggagaaat agatggattt atggttttct gaagttcata
    11701 ctccagatgt caaattgtct ctgagaacag ccaagcaact ttacgctgga aaaagtgaat
    11761 ggcaggatat cgaagtcttg gatacgccag cttttgggaa aatactgatt ttaaatggcc
    11821 atgtcttgtt ctcagatgcg gatgatttcg tctacaatga aatgaccgtt cacgttccca
    11881 tggctgtcca cccaaatcca aagaaagtat tggttattgg gggtggtgac ggcggtgttg
    11941 cccaagtatt aaccctctat cctgaactgg agcaaattga tattgtggaa ccggatgaga
    12001 tgttggtcga ggtctgtcgt gagtatttcc cagactttgc tgcagggcta gatgatcctc
    12061 gtgttaccat ttactaccaa aatgggctac gctttttgcg aaactgcgaa gatgattacg
    12121 atattatcat caacgatgcg acagatccat ttggccatac ggaaggactc tttaccaagg
    12181 aattctacgg caatagttat cgagctctga aggaagacgg catcatgatt taccagcatg
    12241 ggagtccctt ctttgacgag gatgagtcgg cctgccgaag catgcaccgc aaggtcaatc
    12301 aagcctttcc aatcagtcgg gtttatcagg cccatattcc aactagccca gctggctatt
    12361 ggttgtttgg atttgcatcg aaaaaatacc accctgtcaa agattttgac aaggaaggct
    12421 ggaaaaaacg ccagcttttc acagaatact acactgcaaa cttacacgtg ggagccttta
    12481 tgttgcccaa gtatgttgag gacattttag aagaagagga aggaaaaaaa tgagtcgttt
    12541 actagttatt ggttgtgggg gcgttgccca agttgctatt tcaaagattt gtcaagatag
    12601 cgaaacattt acagagatta tgattgctag ccgtaccaag tcaaaatgcg atgacttgaa
    12661 agcgaagcta gaaggcaaaa caagtactaa aattgaaact gcagcacttg atgctgacaa
    12721 ggttgaagaa gtgattgccc tgattgaaag ctacaaacca gaagctgttt tgaatgtagc
    12781 tctgccttat caagatttaa ccattatgga tgcttgtttg gcaacaggtg ttcactatat
    12841 cgatacagcc aactacgaag cagaagacac agaagaccct gagtggcgtg ctatctacga
    12901 aaaacgttgt aaggaacttg gttttacagc ctactttgac tactcatggc agtgggctta
    12961 tcaagagaaa ttcaaagaag caggcttgac tgctcttctt ggttctggtt ttgacccagg
    13021 tgtaactagt gtcttttcag cttatgccct caaacactat tttgatgaaa tccattatat
    13081 cgacatttta gactgtaatg gcggtgacca cggttatcca tttgcaacca actttaatcc
    13141 agaaattaat ctccgtgagg tttctgcgcc aggttcttac tgggaagatg ggaaatgggt
    13201 cgaagtcgaa gctatgtcta tcaagcgtga gtatgatttc cctcaagttg gacaaaaaga
    13261 tatgtatctc cttcaccatg aagaaatcga atcattggcc aagaacattc caggtgtcaa
    13321 acgcattcgt ttctttatga cttttggtca atcttacttg acgcacatga aatgtcttga
    13381 aaatgttgga ctccttcgta cggataccat taactttaac ggccaagaaa ttgttccaat
    13441 tcaatttttg aaagccttgc ttccagatcc tgccagtctt gggccacgta cagtcggaaa
    13501 aaccaatatt ggatgtatct ttacaggtgt caaagacggt gtcaaaaaga ctatctatat
    13561 ctacaatgtc tgcgaccatc aggaatgtta cgcagaggtt ggttcgcaag ctatttctta
    13621 tacgacagga gttccagcca tgattgggac aaaattagtc atgaacggaa cttggaaaca
    13681 agctggagtg tataaccttg aggagttaga tccagatcca ttcatggaag ctttgaatga
    13741 gtatggtttg ccatgggttg tggttgaaaa tccacaaatg gtggactaat gaagttagaa
    13801 caagtaccaa caccagccta tgttattgac ttggccaagt tagaagctaa ttgccgcatt
    13861 ctacaatatg tacaagaaga ggccggttgc aaggtcttgc ttgcccagaa ggcatattcc
    13921 ctctacaaaa cttatccctt gattagccag tatctatcag gtacgacagc tagtggactc
    13981 tatgaggcca aattggcaag ggaagaattt cctggtgaag tccatgtatt tgcgcctgct
    14041 ttcaaggatg cagacttgga ggaattgcta gagataatgg accatatcgt ctttaactca
    14101 gagagacagt tgcgtaaaca cggtccgcgt tgtcgagagg ctggtgtcag tgttggtttg
    14161 cgcctcaacc ctcagtgttc aactcaagga gatcacgcgc tctatgaccc ttgtgcacca
    14221 ggttctcgct ttggagttac tatagacaag attccgagtg atttgctaga tttggttgac
    14281 ggacttcatt ttcataccct ttgcgagcag ggagcagatg atttacaaac aactttgaaa
    14341 gcagtagaag aacagtttgg tccctactta catgaggtaa aatggctcaa tatgggtggt
    14401 ggtcatcata ttacaagaga aggttacgat gtggatttgc tgatttcaga aatcaagcgt
    14461 atccgaaaaa cttacaatct tgaaatctat atcgagcctg gtgaagccat tgcgcttaat
    14521 gcgggttatt tagcaactga ggtattagat attgtagaaa acggtatgga aatcttggtt
    14581 ttagacgcct ctgcgacctg ccatatgcct gatgtacttg agatgcccta tcgtccacct
    14641 ttgagaaatg gctttgagtc acaggaaaaa gcccatacct acagactttc ttctaatacc
    14701 tgtctgacgg gcgatgtgat tggtgattat agttttgaaa atccagtcca aatcggagac
    14761 agactttatt ttcaagacat ggccatttat tcttttgtca aaaataatac ctttaatggt
    14821 attggattgc caagtctcta tctcatggac gaacagggag actgtagctt actcaaagct
    14881 tttggctatc aagactttaa agggagatta tcatgatgga cagtccaaaa aaattaggct
    14941 atcacatgcc agcagagtac gaaccccatc atggtaccct catgatatgg ccgactcgac
    15001 caggatcatg gccttttcaa ggaaaggctg ctaaaagagc atttactcag atcatcgaga
    15061 ccatagcaga aggggaaaga gtctatcttt tggtggagca ggcctatcta tctgaagccc
    15121 aatcctatct tggagacaag gttgtttatt tagacattcc caccaatgat gcctgggcgc
    15181 gtgatactgg cccaaccatt ctcgtcaatg ataaaggtaa gaaattagcc gtggattggg
    15241 cctttaatgc ttggggaggc acctatgatg gtctttatca agattatgaa gaggatgacc
    15301 aagtagccag tcgttttgct gaggccttgg aaaggcctgt ctatgatgct aaaccttttg
    15361 tactggaagg aggcgcaatc catagcgatg gtcaaggaac tattctcgta actgaaagtt
    15421 gcttgcttag tcctggtcgc aatcctaacc tgactaaaga ggagattgaa aacacattat
    15481 tagaaagtct tggtgctgaa aaagttattt ggcttcctta tggtatttat caggatgaaa
    15541 ccaatgaaca cgtcgataat gttgctgcct ttgttggtcc tgctgagctt gttttggctt
    15601 ggacagatga cgaaaatgat ccccagtatg ccatgtcaaa agcagatctc gaactcttag
    15661 aacaggaaac agatgcaaaa ggttgtcact tcaccattca taaattgcct atccctgcag
    15721 ttcgacaagt tgtgacagaa gaagatttgc caggctacat ctatgaagaa ggagaagaaa
    15781 agcgatacgc aggtgaacga ctagcagctt cctacgtaaa cttttatatc gccaacaagg
    15841 ctgtcttggt tccacagttt gaggatgtaa acgaccaagt ggccttagat atcctcagca
    15901 agtgtttccc agaccgtaaa gttgtcggaa taccagccag agatattctc ttaggtggtg
    15961 gcaatatcca ctgtatcacc caacaaattc cagaatagga gaaaaagatg agaaatgtaa
    16021 gagttgcaac cattcagatg caatgcgcta aggatgtggc aacaaatatc caaaccgcag
    16081 agcgtttagt acgtcaggct gctgagcaag gagcccaaat tattctcttg cccgagttgt
    16141 ttgaacatcc ctatttctgt caggaacgtc agtatgacta ctaccagtat gcccaatctg
    16201 tagcggaaaa tactgccatt cagcatttta aggtgattgc taaggaacta caagttgttt
    16261 taccaatcag tttctatgaa aaagatggta atgtcttgta taactctatt gccgtcattg
    16321 atgcagatgg ggaagtgctg ggcgtttatc gaaagaccca cataccagat gaccattatt
    16381 atcaagaaaa attctatttc acgcctggta acactggttt caaggtctgg aatactcgct
    16441 atgctaagat tggtatcggt atctgttggg atcaatggtt ccctgaaaca gcgcgctgtc
    16501 ttgcattgaa tggtgctgaa ttgctctttt atccaacagc catcggttca gagccgattt
    16561 tggatacaga tagttgtggt cactggcaac gtactatgca agggcacgca gcagcgaata
    16621 ttgttccagt catcgcagcc aatcgttatg gtttagagga ggttactcct agtgaggaaa
    16681 atggcggaca gagttccagt cttgacttct acggttcctc ctttatgacg gatgaaacag
    16741 gagctattct agaacgagct gaaagacaag aagaagctgt tctgttagct acttataacc
    16801 tagacaaggg agcaagtgaa cgcctaaact ggggcttgtt tcgagataga agaccagaaa
    16861 tgtatagaca aattacagat tagtgtggga gaaatgagag attcattctg ctagactaac
    16921 ttcttattag caactataag atactatggc atctagtaaa tcgattttta tgattcgcta
    16981 ttcttctcta ttgattagtc cgtattttaa aatattagca aaaaagcaaa tagcagtaac
    17041 ttctgtctat ttgcttttct tttttataga atatatttct caatagcacg cgcaacgccg
    17101 tcttcttcgt tgcttgaggt aacggcatcc gcaagagatt tgacataatc gctggcattt
    17161 cccattgcaa tcccaagccc tgcaaactgg agcatttcga tatcgttatt agcatcgccc
    17221 atggccataa tctctgagga atcaatcttc aaaatctcag ctagtcgtga aagagcagta
    17281 gcctttgtcg ttccaagtgg cattgcttca taaatgacag gctgcgaacg aactccactg
    17341 aatcgttggc aaagctcttc agcaaaacgc tgctcaaaat cgtctgtttg ttcttttgtt
    17401 cctaaaaaca taccttggaa catccggaac tttccactag tcgcttcctc aagagaaatt
    17461 tcagtcaggt ctgaaaatac tagtttagca tcattttcaa taacttgatt gggctttcca
    17521 ccgagaacaa aataatgtga ctcgtcaaaa agtgtcaact gaacatcact cttttcagca
    17581 aggtcataga ggtattcgat gtcagctgga ctaagttctt gccagtcaac caagccccag
    17641 tcgctagtct ggtgagttga acaaccgttg ttaacaatca catactcatt ctggaggtcg
    17701 agtcccagtt ttttgtagta ggggaggaca ccgaaaaggg ggcgacccgt acagagaacc
    17761 agtttgacac ctttttcaat ggctttgtga atagcagtaa tgtgagcttg tgggatttcc
    17821 ttggcttcat tgaggagggt gccgtccata tccaaggcta gtagtttaat cataggtctt
    17881 ccttctttat cttttgctat tattatagca tattttggag aagaaattga tagaaagctt
    17941 gagactaatt gattttatag tttaagatgt tttgatgaca attcatgatt tgaagaggat
    18001 atttcgcaaa gatatgctat actatgtttg tcaatgttgc
//
LOCUS       DAVLBN010000044        17598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLBN010000044 DAVLBN010000000
VERSION     DAVLBN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.044"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(162..365)
                     /locus_tag="VXC24_001502"
     CDS             complement(162..365)
                     /locus_tag="VXC24_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493599.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(358..1440)
                     /locus_tag="VXC24_001503"
     CDS             complement(358..1440)
                     /locus_tag="VXC24_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0493600.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1566..2348)
                     /locus_tag="VXC24_001504"
     CDS             complement(1566..2348)
                     /locus_tag="VXC24_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0493601.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2348..3691)
                     /locus_tag="VXC24_001505"
     CDS             complement(2348..3691)
                     /locus_tag="VXC24_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0493602.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3803..5119)
                     /locus_tag="VXC24_001506"
     CDS             complement(3803..5119)
                     /locus_tag="VXC24_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0493603.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5313..6539
                     /locus_tag="VXC24_001507"
     CDS             5313..6539
                     /locus_tag="VXC24_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0493604.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6738..8312
                     /locus_tag="VXC24_001508"
     CDS             6738..8312
                     /locus_tag="VXC24_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0493605.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8576..9364
                     /gene="codY"
                     /locus_tag="VXC24_001509"
     CDS             8576..9364
                     /gene="codY"
                     /locus_tag="VXC24_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0493606.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9364..9939
                     /locus_tag="VXC24_001510"
     CDS             9364..9939
                     /locus_tag="VXC24_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0493607.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10021..10106
                     /locus_tag="VXC24_001511"
     tRNA            10021..10106
                     /locus_tag="VXC24_001511"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10055..10057,aa:Leu,seq:aag)
     gene            10389..11519
                     /gene="ugpC"
                     /locus_tag="VXC24_001512"
     CDS             10389..11519
                     /gene="ugpC"
                     /locus_tag="VXC24_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0493608.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11666..11812)
                     /locus_tag="VXC24_001513"
     CDS             complement(11666..11812)
                     /locus_tag="VXC24_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493609.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12020..12778
                     /locus_tag="VXC24_001514"
     CDS             12020..12778
                     /locus_tag="VXC24_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0493610.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12865..13377
                     /locus_tag="VXC24_001515"
     CDS             12865..13377
                     /locus_tag="VXC24_001515"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0493611.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13559..14503
                     /locus_tag="VXC24_001516"
     CDS             13559..14503
                     /locus_tag="VXC24_001516"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0493612.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14512..15189
                     /locus_tag="VXC24_001517"
     CDS             14512..15189
                     /locus_tag="VXC24_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0493613.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15287..16045
                     /locus_tag="VXC24_001518"
     CDS             15287..16045
                     /locus_tag="VXC24_001518"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0493614.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16083..17588
                     /gene="lytC"
                     /locus_tag="VXC24_001519"
     CDS             16083..17588
                     /gene="lytC"
                     /locus_tag="VXC24_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0493615.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5282 a         3172 c         3922 g         5222 t
ORIGIN      
        1 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
       61 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      121 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      181 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
      241 tcattccaga cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa
      301 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
      361 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
      421 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
      481 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
      541 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
      601 tttttcgatg atctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
      661 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
      721 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
      781 ccccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
      841 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc
      901 acgtttcatg gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat
      961 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1021 tacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttttcaaa
     1081 ctcagcagtt tcaaaaattg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1141 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1201 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     1261 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     1321 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     1381 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     1441 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     1501 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     1561 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     1621 ctgaggatat cctcataggc agggagttgg atatcctgac catatttctt cttgagggca
     1681 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     1741 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     1801 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     1861 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     1921 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     1981 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2041 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2101 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2161 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     2221 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     2281 tagaggtggg caatgttgag ctgatagggg taattgccat cttttgagga aagtgaagta
     2341 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     2401 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     2461 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     2521 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     2581 ccatgtcagt gatttgttca aagtctgcat cccagatcca gctagtgtca attccatctg
     2641 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     2701 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     2761 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     2821 tgagttgcga atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga
     2881 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     2941 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3001 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3061 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3121 ccttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3181 gtggactgtc tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata
     3241 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag
     3301 taatgacaaa aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa
     3361 tttcgaggac ggcaatattt ttcccagttt tagaagattt ggctgttagg aaggttgttg
     3421 caatccctgt aatcatgttg gcaccgcttg ggttggttag aacttgacca taaacctctt
     3481 ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga
     3541 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     3601 tccctgggag cgtacttcca cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag
     3661 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcacaaa agtatatcac
     3721 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     3781 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     3841 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     3901 cagtaataat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     3961 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4021 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4081 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4141 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4201 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4261 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4321 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4381 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4441 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccatgt
     4501 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4561 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4621 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     4681 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     4741 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     4801 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatatcgacg ccagtaccag
     4861 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     4921 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     4981 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5041 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5101 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5161 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa tatgaaaacg cttttcaggc
     5221 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5281 gatagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5341 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5401 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5461 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5521 cgagagtcat ggggagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5581 ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc ttatggcatt ttaggtgggc
     5641 ttggtttggg agcaggctat attacccctg tgtcaacgat tataaaatgg tttcctgata
     5701 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     5761 gtcccatagc gcaacatctc atcgcagggg tagggcttgt agaaactttt tatattttag
     5821 gtgcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     5881 aagagcttgc aattttatct gcttcaggga aagaaaaaac agactctctg acgcaaggga
     5941 tgactgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6001 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6061 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtat tttggggatt ttcaatggat
     6121 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6181 tattactgct tgtcaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6241 tatttgtagt tgctatgtct attttgatga cttgctatgg agctggtttt tctttgattc
     6301 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggttatattt
     6361 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6421 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6481 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6541 tttctgtaga aatggggcta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6601 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     6661 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     6721 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctagcag
     6781 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     6841 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     6901 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gctttggtca
     6961 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7021 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7081 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7141 aacgcaaggc cttgaaatta caagacattg aaacccttat ccttgacgaa gcggatgaaa
     7201 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7261 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7321 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7381 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7441 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7501 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7561 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7621 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     7681 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     7741 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     7801 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     7861 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     7921 gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     7981 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8041 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8101 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8161 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8221 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8281 gctttgttat tcgtaacaag ggcgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8341 tttatataag gagaccgaat gtgaaaagac aaataaaatt attatattat cttttataat
     8401 gttatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta attaaaaata
     8461 ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt cagataatta
     8521 ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt gaaaaatggc
     8581 acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag aggagcagtt
     8641 gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta ttcattgcaa
     8701 tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt ataaaacaaa
     8761 tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact acgttcaagg
     8821 ggctaatatg atttacgaaa cagaagcaaa cttgcctgtt gagcatgata tgagtatttt
     8881 ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac cgattcatgt
     8941 atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat tcgaagatga
     9001 ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc ttaacttcca
     9061 acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg cggtcaatac
     9121 cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa atggaaatga
     9181 agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct ctgtgattgt
     9241 caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac ttggaatgaa
     9301 gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga aaagagatta
     9361 ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc tgatagtggg
     9421 aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa ggtaactcga
     9481 ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga agaaaacgat
     9541 tgtttccatc cggaaagtaa gttattttct cctcataatc tgattgggac gagtggacgg
     9601 aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag tcgtgtcttt
     9661 tggatggata aacgccatta ctcagctttt tcagggactg acctagatat tcgtttgaga
     9721 gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg tgtcctacat
     9781 acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc agctgttgct
     9841 tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac actcggagct
     9901 aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg aaaatgaaaa
     9961 aatttgaaaa aaagtgttga caagcatccc aaaagttgat atactagtaa agtaatcgat
    10021 gcggggatgg cggaattggc agacgcgcag gactaaggat cctgtgaccg ctttaggtcg
    10081 tgagggttca agtccctctc tccgcatagg aaaagagtta gctaaagcta gctcttttgt
    10141 atttctctaa aaaattagaa tccagtcaaa tgtagtggag aatcagcgaa aatatgggaa
    10201 aactgatcct tgtttctgct tttgtcatag aagaataata aagattatct tcttcaaatt
    10261 ctccgatatt ctctaaagtt ttgtgcaagt tgcacagaac ttttttattt ttttggtcat
    10321 cttgccatag aaatataaag cgttttcatc tataatataa ttatcaaaag acaaaaggag
    10381 ttcacctcat ggtagaattg aatcttaaaa atatttacaa aaaatatcca aacagcgaac
    10441 actattcagt tgaagatttc aacttgaaca tcaaagataa agaatttatc gttttcgtag
    10501 gaccttcagg atgtggtaaa tcaactacac tccgtatgat tgctggtctt gaagacatta
    10561 cagaaggtac tgcatctatc gatggcgtgg ttgtcaacga cgtagctcca aaagaccgtg
    10621 atatcgccat ggtattccaa aactacgctc tttacccaca catgactgtt tatgacaaca
    10681 tggctttcgg tttgaaattg cgtaaataca gcaaagaaga cattaacaaa cgtgttcaag
    10741 aagcagctga aatacttgga ttgaaagaat tcttggaacg taaaccagct gacctttcag
    10801 gtggtcaacg tcaacgtgtt gccatggggc gtgcgattgt ccgtgatgcg aaagtattct
    10861 tgatggacga acctttgtca aacttggatg ccaaacttcg tgtatcaatg cgtgctgaaa
    10921 tcgctaaaat tcaccgtcgt atcggagcta caactatcta tgtaactcac gaccaaacag
    10981 aagcgatgac acttgcagac cgtatcgtta ttatgtcagc tactaagaac cctgctggta
    11041 caggtactat cggacgtgta gaacaaatcg gtactcctca agaagtttac aaaaatccag
    11101 ttaacaaatt cgttgcagga ttcatcggaa gcccagctat gaacttcatc accgtgaaat
    11161 tggttggtag cgaaattgtt tctgacggtt tccgtttgaa agtgccagaa ggagcattga
    11221 aagttcttcg tgaaaaaggc tacgaaggaa aagaattgat ctttggtatc cgtccagaag
    11281 acgtgaatgc agaacctgct ttccttgaaa cattcccaga ctgtgttgta aaagcgacta
    11341 tctctgtatc agaactgctt ggttcagaat ctcaccttta ctgccaagtt ggtaaagacg
    11401 agtttgttgc aaaagttgat gctcgtgact acttgcaaac aggtgcaaca gttgagcttg
    11461 gatttgactt gaacaaagca cacttcttcg atgtagaaac tgaaaaaaca atctactaaa
    11521 ataaataaaa ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga
    11581 tatcagttaa tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata
    11641 ttatgcatct atattgtgat gctctttaat actcttcgaa aatctcttca aaccacgtca
    11701 acgtcgcctt gccgtacgta tgattactga tttcgtcagt tttatctgca acctcaaaga
    11761 tgtactttga gcagcttacg gctagtttcc tagtttgctc tttgatttcc attgagtatt
    11821 atttgtgggt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    11881 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    11941 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    12001 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    12061 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    12121 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    12181 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    12241 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    12301 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    12361 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    12421 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    12481 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    12541 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    12601 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    12661 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    12721 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    12781 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    12841 aaaaactttg aaagaaagaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat
    12901 tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct
    12961 tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc
    13021 gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt
    13081 ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat
    13141 gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa
    13201 cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag
    13261 atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa
    13321 ttgaacggcc gtgaaaaaat tggtgactac gactacaaag ttcttatgca ttattaatga
    13381 aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta taactagtta
    13441 gagaaaaact ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt
    13501 gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg agagggttat
    13561 gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt
    13621 tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt
    13681 aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac
    13741 acccctacaa ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg
    13801 ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga
    13861 tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg
    13921 ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat
    13981 ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga
    14041 cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag
    14101 aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga
    14161 ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg gggtttctat
    14221 tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga
    14281 taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga
    14341 aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc
    14401 agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgattg
    14461 gagaaagata gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat
    14521 ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag
    14581 gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg
    14641 acaggcttag aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg
    14701 gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc
    14761 gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat
    14821 gacctgtttg gagcagttcg ttcaagttca gaccagctaa cacctcaaaa ccagctcaag
    14881 gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag
    14941 gatttgatca agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt
    15001 cgtgaagctg ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac
    15061 tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa
    15121 gcaagcaatc ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg
    15181 aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat
    15241 tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc
    15301 atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga
    15361 agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc
    15421 tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca
    15481 aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa
    15541 agaaatcggt actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga
    15601 aactgatgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat
    15661 catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg
    15721 tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat
    15781 cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag atgatgcaca
    15841 aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga
    15901 caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc
    15961 ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt
    16021 ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc
    16081 agatgtctgt tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa
    16141 gtatctgttt actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa
    16201 aaacttcgca ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata
    16261 aaacgcaaac gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt
    16321 atgtaaagga tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg
    16381 cttggtttta tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact
    16441 acctgaaatc aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga
    16501 gttggtttta tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa
    16561 ataagtggta ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt
    16621 atttcttgaa tggtcaagga gctatgatac aaaatgaatg gctctatgat ccagcctatt
    16681 ctgcttattt ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg
    16741 gcggcaaatg gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca
    16801 actactattt gactggaagt ggtgccatgg cgactgacga agtgattatg gatggtgctc
    16861 gctatatctt tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg
    16921 ttcacagaga tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac
    16981 atgctaagaa aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg
    17041 ttattgatga gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag
    17101 acaaggaatt ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct
    17161 atctctatac ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg
    17221 aacttataaa gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact
    17281 gggaatatgt aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca
    17341 tcaacaagta catggacacg atgaagcagg cgggttatca aaatgtatat gtctatagct
    17401 atcgtagttt attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg
    17461 tagcggccta tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt
    17521 ggcaatatac ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt
    17581 ggtattaagc gatgattt
//
LOCUS       DAVLBN010000045        17403 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLBN010000045 DAVLBN010000000
VERSION     DAVLBN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.045"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..123)
                     /gene="comC"
                     /locus_tag="VXC24_001520"
     CDS             complement(<1..123)
                     /gene="comC"
                     /locus_tag="VXC24_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0493616.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFN"
     gene            complement(288..361)
                     /locus_tag="VXC24_001521"
     tRNA            complement(288..361)
                     /locus_tag="VXC24_001521"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Arg,seq:tct)
     gene            complement(405..884)
                     /gene="rlmH"
                     /locus_tag="VXC24_001522"
     CDS             complement(405..884)
                     /gene="rlmH"
                     /locus_tag="VXC24_001522"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0493617.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            1067..2248
                     /locus_tag="VXC24_001523"
     CDS             1067..2248
                     /locus_tag="VXC24_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0493618.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            2306..3064
                     /locus_tag="VXC24_001524"
     CDS             2306..3064
                     /locus_tag="VXC24_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0493619.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            3277..4638
                     /gene="dnaA"
                     /locus_tag="VXC24_001525"
     CDS             3277..4638
                     /gene="dnaA"
                     /locus_tag="VXC24_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0493620.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            4797..5933
                     /gene="dnaN"
                     /locus_tag="VXC24_001526"
     CDS             4797..5933
                     /gene="dnaN"
                     /locus_tag="VXC24_001526"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0493621.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            5998..6192
                     /locus_tag="VXC24_001527"
     CDS             5998..6192
                     /locus_tag="VXC24_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0493622.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            6276..7391
                     /gene="ychF"
                     /locus_tag="VXC24_001528"
     CDS             6276..7391
                     /gene="ychF"
                     /locus_tag="VXC24_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0493623.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            7462..8031
                     /locus_tag="VXC24_001529"
     CDS             7462..8031
                     /locus_tag="VXC24_001529"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0493624.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            8032..11541
                     /gene="mfd"
                     /locus_tag="VXC24_001530"
     CDS             8032..11541
                     /gene="mfd"
                     /locus_tag="VXC24_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0493625.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            11599..11865
                     /locus_tag="VXC24_001531"
     CDS             11599..11865
                     /locus_tag="VXC24_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0493626.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            11858..12226
                     /locus_tag="VXC24_001532"
     CDS             11858..12226
                     /locus_tag="VXC24_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0493627.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            12346..13614
                     /locus_tag="VXC24_001533"
     CDS             12346..13614
                     /locus_tag="VXC24_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0493628.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            13611..14888
                     /gene="tilS"
                     /locus_tag="VXC24_001534"
     CDS             13611..14888
                     /gene="tilS"
                     /locus_tag="VXC24_001534"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0493629.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            14892..15434
                     /gene="hpt"
                     /locus_tag="VXC24_001535"
     CDS             14892..15434
                     /gene="hpt"
                     /locus_tag="VXC24_001535"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0493630.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            15450..>17403
                     /gene="ftsH"
                     /locus_tag="VXC24_001536"
     CDS             15450..>17403
                     /gene="ftsH"
                     /locus_tag="VXC24_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0493631.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         6021 a         2748 c         3361 g         5273 t
ORIGIN      
        1 attaaagaaa ttaaagatat taaaggactt ttcattcatt ttcctcatct ccccaccttg
       61 aatattttgc aagtcttttt ccttcaaagc tacaaactgt tccaatttaa ctgtgttttt
      121 cataataaaa tctcctaaaa tgttttttct tgtaagctaa cttacaaaaa ccattataca
      181 aaatggaatt tcgttttaga taaaattctc tcaactgtca tttttttctc ccaaagtgta
      241 cttttttaag aaaaaagccg ggaaaattcc cagctttgct attatattga tcccagcagg
      301 attcgaacct gcgaccgttc gcttagaagg cgaatgctct atccagctga gctatgagac
      361 ctaacacaat tattctacca aaaattcaat taaaagtcaa ttttctattt atggtagggg
      421 aatccctgct gaatcgtaaa agcgcgatag atttgttcaa caagaactag tctcattaac
      481 tgatgaggca aggttaggcg accaaaactg acagaaagat tggctctatt ttttacagat
      541 gatgataatc ctaaacttcc cccaataata aaagtaagag tagaaaatcc ttttatagaa
      601 gtttcttcta actgcttact aaattcttct gagaagaaag ttttcccttc aatggctaac
      661 acaataacga aatcacggtc agcaattttt gataaaattc tctgaccttc tatttctaaa
      721 atcttttgat tttctgattc actggcctta tctggtgttt tttcatctga taactcaatc
      781 atttcaaact tagcaaatct agaaattcgt tttgaatact ctgcgatacc atcttttaaa
      841 tacttttctt tcagtttccc aactgttaca actttaattt tcatgactct attctaacat
      901 attctctatt ttttcacatc ttattcacaa aataaaaaat agatttcaat taagaaaatc
      961 acagtttcaa aagagttatc cacagtttgt gtaaaacttt tgtgtttaag ttataattaa
     1021 gctagtcagt ttatactttc agtaattcaa acatatggag gcaaatatga aacatctaaa
     1081 aacattttac aaaaaatggt ttcaattatt agtcgttatc gtcattagct tttttagtgg
     1141 agccttgggt agtttttcaa taactcaact aactcaaaaa agtagtgtaa acaactctaa
     1201 caacaatagt actattacac aaactgccta taagaacgaa aattcaacaa cacaggctgt
     1261 taacaaagta aaagatgctg ttgtttctgt tattacttat tcggcaaaca gacaaaatag
     1321 cgtatttggc aatgatgata ctgacacaga ttctcagcga atctctagtg aaggatctgg
     1381 agttatttat aaaaagaatg ataaagaagc ttacatcgtc accaacaatc acgttataaa
     1441 tggcgccagc aaagtagata ttcgattgtc agatgggact aaagtacctg gagaaattgt
     1501 cggagctgac actttctctg atattgctgt cgtcaaaatc tcttcagaaa aagtgacaac
     1561 agtagctgag tttggtgatt ctagtaagtt aactgtagga gaaactgcta ttgccatcgg
     1621 tagcccgtta ggttctgaat atgcaaatac tgtcactcaa ggtatcgtat ccagtctcaa
     1681 tagaaatgta tccttaagat cggaagatgg acaagctatt tctacaaaag ccatccaaac
     1741 tgatactgct attaacccag gtaactctgg cggcccactg atcaatattc aagggcaggt
     1801 tatcggaatt acctcaagta aaattgctac aaatggagga acatctgtag aaggtcttgg
     1861 tttcgcaatt cctgcaaatg atgctatcaa tattattgaa cagttagaaa aaaacggaaa
     1921 agtgacgcgt ccagctttgg gaatccagat ggttaattta tctaatgtga gtacaagcga
     1981 catcagaaga ctcaatattc caagtaatgt tacatctggt gtagttgttc gttcggtaca
     2041 aagtaatatg cctgccaatg gtcaccttga aaaatacgat gtaattacaa aagtagatga
     2101 caaagagatt gcttcatcaa cagacttaca aagtgctctt tacaaccatt ctatcggaga
     2161 caccattaag ataacctact atcgtaacgg gaaagaagaa actacctcta tcaaacttaa
     2221 caagagttca ggtgatttag aatcttaatt gacatctatg taaagaaagc tttacataag
     2281 agaaaagatg tgttagtgta gaatcatgga aaaatttgaa atgatttcta tcacagatat
     2341 acaaaaaaat ccctatcaac cccgaaaaga atttgataga gaaaagctag atgaactagc
     2401 acagtctatc aaagaaaatg gggtcattca accgattatt gttcgtcaat ctcctgttat
     2461 tggttatgaa atccttgcag gagagagacg ctatcgggct tcacttttag ctggtctacg
     2521 gtctatccca gctgttgtta aacagatttc agaccaagag atgatggtcc agtccattat
     2581 tgaaaattta cagagagaaa atttaaaccc aatagaagaa gcacgcgcct atgaatctct
     2641 cgtagagaaa ggattcaccc atgctgaaat tgcagataag atgggcaagt ctcgtccata
     2701 tatcagcaac tccattcgtt tactttcctt gccagaacag attctctcag aagtagaaaa
     2761 tggcaaacta tcacaagccc atgcgcgttc cctagttggg ttaaataagg aacaacaaga
     2821 ctatttcttt caacggatta tagaagaaga tatttctgta aggaagttag aagctcttct
     2881 gacagagaaa aaacaaaaga aacagcaaaa aactaattat ttcatacaaa atgaagaaaa
     2941 acagttaaga aaactactcg gattagatgt agaaattaaa ctatctaaaa aagacagtgg
     3001 aaaaatcatt atttattttt caaatcaaga agaatatagt agaattatca acagcctgaa
     3061 ataaggctgt tcttttattt ttttatctca caaggttatc cactatgttt ttcgataaaa
     3121 agcttaataa atcaataatt tcttctttta tccccaacct gtggataaag tttagtaaca
     3181 ttgtggatta tttttcacag cttgtggaaa attcttgcta tctatggtaa aatatctcta
     3241 gtattaaact tttaaatagt aaaggaggaa aaaggattga aagaaaaaca attttggaat
     3301 cgtatattag aatttgcaca agaaagactg actcgatcca tgtatgattt ctatgctatt
     3361 caagctgaac tcatcaaggt agaggaaaat gttgccacta tatttctacc tcgctctgaa
     3421 atggaaatgg tctgggaaaa acaactaaaa gatattattg tagtagctgg ttttgaaatt
     3481 tatgacgctg aaataactcc ccactatatt ttcaccaaac ctcaagatac gactagctca
     3541 caagttgaag aagctacaaa tttaactctt tatgactata gtccaaagtt agtatctatt
     3601 ccttattcag atacgggatt aaaagaaaag tatacctttg ataactttat tcaaggggat
     3661 ggaaatgttt gggctgtgtc agccgcttta gctgtctctg aagatttggc tctgacctat
     3721 aaccctcttt ttatctatgg aggaccaggc cttggtaaga ctcacttatt aaacgctatt
     3781 ggaaatgaaa ttctaaaaaa tattcctaat gcgcgtgtta aatatatccc tgccgaaagc
     3841 tttattaatg actttcttga tcacctaaga cttggggaaa tggaaaagtt taaaaagacc
     3901 tatcgtagtc ttgatctttt gttaatcgat gatatccagt cactcagcgg aaaaaaagtc
     3961 gcaactcagg aagaattttt caataccttt aacgcccttc atgacaagca aaaacagatt
     4021 gtcctaacga gtgatcgtag tccaaaacat ctagaagggc tcgaggagag gcttgtcacg
     4081 cgttttagtt ggggattgac acaaactatc acaccccctg actttgaaac acgtattgcc
     4141 attttacaaa gtaaaacgga acatttaggc tacaatttcc aaagtgatac tctagaatac
     4201 ctagctgggc aatttgattc aaatgttcga gatcttgagg gagccatcaa cgacatcact
     4261 ttaattgcca gagtaaaaaa aatcaaggat atcactattg atattgctgc agaagccatt
     4321 agagcccgca aacaagatgt tagccaaatg ctcgtcatcc caattgataa aatccaaact
     4381 gaagttggta acttttatgg tgttagtatc aaagaaatga agggaagtag acgccttcaa
     4441 aatattgttt tggcccgtca agtagccatg tatttatcta gagaactaac agataatagt
     4501 cttccaaaaa ttgggaagga atttggggga aaagatcata ccacagtcat tcatgcccat
     4561 gccaaaataa aatctttgat tgatcaagac gataatttac gtttagaaat tgaatcaatc
     4621 aaaaagaaaa tcaaataatt tgtggataac ttttagtttt ttatcttttt tatccacatt
     4681 ttttaaacaa gctaaaaaac ttgataggac ttgtttaaag gctgttttcc acagatttca
     4741 cagactctat tattactatt atctttctaa tactaaaaat aaataaagga gaatccatga
     4801 ttcatttttc aattaataaa aatttatttc tacaagcatt aaatactact aagagagcta
     4861 ttagttctaa aaatgccatt cctattttat caacaataaa aattgacgtg accaatgaag
     4921 gtattacttt aattggttca aatggtcaaa tttcaattga aaattttatt tctcaaaaaa
     4981 atgaagatgc tggtttgtta attacttctt taggttcgat ccttcttgaa gcttctttct
     5041 ttatcaatgt agtatctagt ttacctgatg taactcttga ttttaaagaa attgaacaaa
     5101 atcaaattgt tttaaccagt ggcaaatcag aaattaccct aaaaggaaaa gatagcgaac
     5161 aatatccacg aatccaagaa atttcagcaa gcactccttt aatacttgaa acaaaattac
     5221 tcaagaaaat tattaatgaa acagcctttg ctgcaagtac acaagagagt cgtccgattt
     5281 taacaggtgt ccacttcgta ttgagtcaac acaaagagtt aaaaacagtt gcaacagact
     5341 ctcatcgcct aagccagaaa aaattgactc ttgaaaaaaa tagtgatgat tttgatgtcg
     5401 taattcctag ccgttctcta cgcgaatttt cagcggtatt tacagatgat atcgaaactg
     5461 tagagatttt ctttgccaat aaccaaatcc tctttagaag cgaaaatatt agcttctata
     5521 ctcgtctcct agaaggaaac tatcctgata cagatcgctt gattccaaca gactttaaca
     5581 ctactattac ttttaatgtg gtaaacttac gccagtcaat ggagcgtgcc cgtcttttat
     5641 caagtgcgac tcaaaatggt actgtgaaac ttgaaattaa ggatggggtt gttagcgccc
     5701 atgttcactc tccagaagtt ggtaaagtaa acgaagaaat cgatactgat caggttactg
     5761 gtgaagattt gaccattagt ttcaacccaa cttacttgat tgattctctt aaagctttaa
     5821 atagcgaaaa ggtgaccatt agctttatct cagctgttcg tccatttact cttgtgccag
     5881 cagatactga cgaagacttc atgcagctca ttacaccagt tcgtacaaat taagtgaaag
     5941 aggttgagcc tggctcgcct cttttatgat ataatcgaaa aagaaaagga gagtagtatg
     6001 tatcaagttg gaaattttgt tgagatgaaa aaatcacacg cttgtacaat caagtcgact
     6061 ggtaaaaagg ctaatcgttg ggaaattaca cgtgtaggag cagatatcaa aataaaatgc
     6121 agtaattgtg agcatgttgt catgatgggg cgatatgatt ttgagcgaaa aatgaataaa
     6181 attattgact gagaaccctt agttagaggg ttagcacttt atcccttttt gtgttataat
     6241 attagggatt gaaatgaaaa cggagaatga gaaatatggc tttgacagca ggtatcgttg
     6301 gtttgccaaa cgttggtaaa tcaacactat ttaatgcaat tacaaaagca ggagcagagg
     6361 cagcaaacta cccatttgcg actattgatc caaatgttgg aatggtggaa gttccagatg
     6421 aacgcctaca aaaactaact gaaatgataa ctcctaaaaa gacagttccc acaacatttg
     6481 aatttacgga tattgcaggg attgtaaaag gagcttcaaa aggagaaggg ctagggaata
     6541 aattcttggc caatattcgt gaagtagatg cgattgttca cgtagttcgt gcttttgatg
     6601 atgaaaatgt gatgcgcgag caaggacgtg aagacgcctt tgtggatcca cttgcagata
     6661 ttgacaccat taacctagaa ttgattcttg cagacttaga atcagtcaat aaacgatatg
     6721 cgcgtgtaga aaagatggca cgtacgcaaa aagataaaga atcagtagca gaattcaatg
     6781 ttcttcaaaa gattaaacca gtcctagaag acgggaaatc agctcgtacc attgaattta
     6841 cagatgagga acaaaaggtt gtcaaaggtc ttttcctttt gacgactaaa ccagttcttt
     6901 atgtagctaa tgtggacgag gatgtggttt cagaacctga ctctatcgac tatgtcaaac
     6961 aaattcgtga atttgcagcg acagaaaatg ctgaagtagt cgttatttct gcgcgtgctg
     7021 aggaagaaat ttctgaattg gatgatgaag ataaaaaaga gtttcttgaa gccattggtt
     7081 tgatagaatc aggtgtagat aagttgacgc gtgcagctta ccacttgctt ggattgggaa
     7141 cttacttcac agctggtgaa aaagaagttc gcgcttggac tttcaaacgt ggtatgaagg
     7201 ctcctcaagc agctggtatt atccactcag actttgaaaa aggctttatt cgtgcagtaa
     7261 ccatgtcata tgaggatcta gtgaaatacg aatctgaaaa ggccgtaaaa gaagctggac
     7321 gcttgcgtga agaaggaaaa gaatatatcg ttcaagatgg cgatatcatg gaattccgct
     7381 ttaatgtcta aaaattaata aatggtgtca attaggttgg aaaaaaattc caaccctttt
     7441 ggcttttgaa aggaaaaata aatgaccaaa ttacttgtag gcttgggaaa tccaggggat
     7501 aaatattttg aaacaaaaca caatgttggt tttatgttga ttgatcaact agcgaagaaa
     7561 cagaatgtca cttttacaca cgataagata tttaaagctg acctagcatc ctttttccta
     7621 aatggagaaa aaatttatct ggttaaacca acgaccttta tgaatgaaag tggaaaagca
     7681 gttcatgctt tattaactta ctatggtttg gatattgacg atttacttat catttacgat
     7741 gatcttgaca tggaagttgg gaaaattcgt ttaagagcaa aaggctcagc aggtggtcat
     7801 aatggtatca agtctattat tcaacatata ggaactcagg tctttaaccg tgttaagatt
     7861 ggaattggaa gacctaaaaa tggtatgtca gttgttcatc atgttttgag taagtttgac
     7921 agggatgatt atatcggtat tttacagtct gttgacaaag ttgacgattc tgtaaactac
     7981 tatttacaag agaaaaattt tgagaaaaca atgcagaggt ataacggata aatggtgacc
     8041 ttattagatt tattctcaga aaatgatcag attaaaaaat ggcatcaaaa tttaactgat
     8101 aagaaaagac aactaatact tggtttatca acatctacta aggctcttgc aattgcaagc
     8161 agtttagaaa aagaagatag gattgtgtta ttgacgtcaa cttatggaga agcagaagga
     8221 cttgttagtg atcttatatc tatcttgggt gaggaactcg tctatccatt tttggtagat
     8281 gatgctccta tggtggagtt tttgatgtct tcacaggaaa aaattatttc acgggttgaa
     8341 gccttgcgtt ttttgactga ttcatctaag aaagggattt tagtttgtaa tatcgcagca
     8401 agtcgattga ttttaccgtc tcccaatgca ttcaaagata gtattgtaaa aatctcagtt
     8461 ggtgaagaat atgatcaaca cgcgtttatc catcagttaa aggaaaatgg ctatcgaaaa
     8521 gttactcaag tacaaactca gggcgaattt agtcttcgag gagatatttt agatattttt
     8581 gaaatatccc agttagaacc ttgtcgaatt gagttttttg gtgatgaaat tgatggtatc
     8641 aggtcatttg aagtagaaac acaattatcg aaagaaaata agacagaact cactatcttt
     8701 ccagctagtg atatgctttt gagagaaaag gattatcaac gaggacagtc agctttagaa
     8761 aaacaaattt caaaaacttt atcacctatt ttgaaatcat acctagaaga aattctttca
     8821 agttttcacc aaaaacaaag tcatgcagac tctcggaagt ttttatcttt gtgctatgat
     8881 aagacatgga ctgtctttga ttatattgaa aaagatactc caatattctt tgatgattat
     8941 caaaaattga tgaatcagta tgaagtcttt gaaagagact tagcgcagta ctttacagaa
     9001 gaattacaga atagtaaagc attttctgat atgcagtatt tttctgatat tgaacaaatc
     9061 tataaaaaac aaagtccagt gacctttttc tctaatcttc aaaagggttt aggaaatctc
     9121 aaatttgaca aaatttatca attcaatcaa tatcctatgc aggaattttt caatcagttt
     9181 tcttttctaa aagaagaaat tgaacgatat aaaaaaatgg attacaccat tattctgcag
     9241 tctagcaatt caatgggaag taaaacattg gaggatatgt tagaggaata tcagattaaa
     9301 ttggattcta gagataagac aaatatctgt aaagaatctg taaacttaat agagggtaat
     9361 ctcagacatg gttttcattt tgtagatgaa aagattttat tgataactga acatgagatt
     9421 tttcaaaaga aattaaagcg tcgttttcga agacaacatg tttcaaatgc agagagatta
     9481 aaagattaca atgaacttga aaaaggggac tatgttgtcc atcatatcca tgggattggt
     9541 caatatctag gaattgaaac cattgaaatc aagggaattc atcgcgatta tgtcagtgtc
     9601 caataccaaa atggtgatca aatttctatc cccgtggaac agattcatct actgtccaaa
     9661 tatatttcaa gtgatggtaa agctccaaaa ctcaataaat taaatgacgg tcattttaaa
     9721 aaggccaagc aaaaggttaa gaaccaggta gaggatatag ctgatgattt aatcaaactc
     9781 tactctgaac gtagtcagtt gaagggtttt gctttctcag ctgatgatga tgatcaagat
     9841 gcctttgatg atgctttccc ttatgttgaa acggatgatc aacttcgtag tattgaggaa
     9901 atcaaaaggg atatgcaggc ttctcagcca atggatcgac ttttagttgg ggatgttggt
     9961 tttggaaaga ctgaagttgc tatgcgtgca gcctttaaag cagtcaatga tcacaaacag
    10021 gttgtcattc tagttccgac gacggtttta gcgcaacagc actatacgaa ttttaaggaa
    10081 cgattccaaa attttgcagt taatgttgat gtgttgagtc gctttagaag taaaaaagag
    10141 cagactgcaa cacttgaaaa attgaaaaac ggtcaagtcg atattttgat tggaacacat
    10201 cgtgttttgt caaaagatgt tgtgtttgct gatttgggct tgatgattat tgatgaggaa
    10261 cagcgatttg gtgtcaagca taaggaaact ttgaaagaac tgaagaaaca agtggatgtc
    10321 ctaaccttga ccgctacgcc aatccctcgt accctccata tgtctatgct gggaatcaga
    10381 gatttgtctg ttattgaaac tccgccgact aatcgctatc ctgttcagac ctatgttttg
    10441 gaaaagaatg atagtgtcat tcgtgatgct gtcttgcgtg aaatggagcg tggaggtcaa
    10501 gtttactatc tttacaacaa agttgacaca attgttcaga aggtttcaga attacaggag
    10561 ttgattccgg aggcttcgat tggatatgtt catggtcgaa tgagtgaagt ccagttggaa
    10621 aatactctat tagactttat tgagggacaa tacgatatct tggtgacgac tactattatt
    10681 gagacagggg tggacattcc aaatgctaat actttattta ttgaaaatgc ggaccatatg
    10741 ggcttgtcaa ccttatatca gttaagagga agagtcggtc gtagtaatcg tattgcttat
    10801 gcttatctca tgtatcgtcc agaaaaatca atcagtgaag tctctgaaaa gagattagaa
    10861 gcgattaaag gatttacaga attgggctct ggctttaaga ttgcaatgcg agatctttcg
    10921 attcgtggag caggaaatct tttaggaaaa tcccagtctg gtttcattga ttctgttggt
    10981 tttgaattgt attcgcagtt attagaggaa gctattgcta aacgaaacgg taatgctaac
    11041 gctaacacaa gaaccaaagg gaatgctgag ttgattttgc aaattgatgc ctatcttcct
    11101 gatacttata tttctgatca acgacataag attgaaattt acaagaaaat tcgtcaaatt
    11161 gacaaccgtg tcaattatga agagttacaa gaggagttga tagaccgttt tggagaatac
    11221 ccagatgtag tagcctatct tttagagatt ggtttggtca aatcatactt ggacaaggtc
    11281 tttgttcaac gtgtggaaag aaaagataat aaaattacaa ttcaatttga aaaagtcact
    11341 caacgactgt ttttagctca agattatttt aaagctttat ccgtaacgaa cttaaaagca
    11401 ggcatcgctg agaataagga attaatggag cttgtatttg atgttcaaaa taagaaagat
    11461 tatgaaattt tagaaggtct gctgattttt ggagaaagtt tattagagat aaaagagtct
    11521 aaggaagaaa attccatttg atatttttct tctataaaat agataaaaat ggtacaataa
    11581 taaattgagg taataaggat gagattagat aaatatttaa aagtatcgcg aattatcaag
    11641 cgtcgtacag tcgcaaagga agtagcagat aaaggtagaa tcaaggttaa tggaatcttg
    11701 gccaaaagtt caacggactt gaaagttaat gaccaagttg aaattcgctt tggcaataag
    11761 ttgctgcttg taaaagtact agagatgaaa gatagtacaa aaaaagaaga tgcagcagga
    11821 atgtatgaaa ttatcagtga aacacgggta gaagaaaatg tctaaaaata ttgtacaatt
    11881 gaataattct tttattcaaa atgaatacca acgtcgtcgc tacctgatga aagaacgaca
    11941 aaaacggaat cgttttatgg gagtggtatt gattttgatt atgctattat ttatcttgcc
    12001 aacttttaat ttagcgcaga gttatcagca attactccaa agacgtcagc aattagcaga
    12061 cttgcaaact cagtatcaaa ctttgagtga tgaaaaggat aaggagacag catttgctac
    12121 caagttgaaa gatgaagatt atgctgctaa atatacacga gcgaagtact attattctaa
    12181 gtcgagggaa aaagtttata cgattcctga cttgcttcaa aggtgataaa atggaaaatt
    12241 tattagacgt aatagagcaa tttttgagtt tgtcagatga aaagctggaa gaattggctg
    12301 ataaaaatca attattgcgt ttacaagaag aaaaggaaag gaagaatgcg taaattctta
    12361 attattttgt tgctaccaag ttttttgacc atttcaaaag tcgttagcac agaaaaagaa
    12421 gtcgtctata cttcgaaaga aatttattac ctttcacaat ctgactttgg tatttatttt
    12481 agagaaaaat taagttctcc catggtttat ggagaggttc ctgtttatgc gaatgaagat
    12541 ttagtagtgg aatctgggaa attgactccc aaaataagtt ttcaaataac cgagtggcgc
    12601 ttaaataaac aaggaattcc agtatttaag ctatcaaatc atcaatttat agctgcggac
    12661 aaacgatttt tatatgatca atcagaggta actccaacaa taaaaaaagt atggttagaa
    12721 tctgacttta aactgtacaa tagtccttat gatttaaaag aagtgaaatc atccttatca
    12781 gcttattcgc aagtatcaat cgacaagacc atgtttgtag aaggaagaga atttctacat
    12841 attgatcagg ctggatgggt agctaaagaa tcaacttctg aagaagataa tcggatgagt
    12901 aaagttcaag aaatgttatc tgaaaaatat cagaaagatt ctttctctat ttatgttaag
    12961 caactgacta ctggaaaaga agctggtatc aatcaagatg aaaagatgta tgcagccagc
    13021 gttttgaaac tctcctatct ctattatacg caagaaaaaa taaatgaggg tctttatcag
    13081 ttagatacga ctgtaaaata cgtatctgca gtcaatgatt ttccaggttc ttataaacca
    13141 gagggaagtg gtagtcttcc taaaaaagaa gataataaag aatattcttt aaaggattta
    13201 attacgaaag tatcaaaaga atctgataat gtagctcata atctattggg atattacatt
    13261 tcaaaccaat ctgatgccac attcaaatcc aaaatgtctg ccattatggg agatgattgg
    13321 gatccaaaag aaaaattgat ttcttctaag atggccggga agtttatgga agctatttat
    13381 aatcaaaatg gatttgtgct agagtctttg actaaaacag attttgatag tcagcgaatt
    13441 gccaaaggtg tttctgttaa agtagctcat aaaattggag atgcggatga atttaagcat
    13501 gatacgggtg ttgtctatgc agattctcca tttattcttt ctattttcac taagaattct
    13561 gattatgata cgatttctaa gatagccaag gatgtttatg aggttctaaa atgagggaac
    13621 aagatttttt aaatcatttt ctcaagaagg gatatttcaa aaagcatgct aaggcggttc
    13681 tagctctttc tggtggatta gattctatgt ttctatttaa ggtattgtct acttatcaaa
    13741 aagagttaga gattgaattg attctggctc atgtgaatca taagcagaga attgaatcag
    13801 attgggaaga aaaggaatta aggaagttgg ctgctgaagc agaacttcct atttatatca
    13861 gcaatttttc aggagaattt tcagaagcgc gtgcacgaaa ttttcgttat gatttttttc
    13921 aagaggtcat gaaaaagaca ggtgcgacag ctttagtcac tgcccaccat gctgatgatc
    13981 aggtggaaac gattttgatg cgcttgattc gaggaactcg cttgcgctat ctatcaggaa
    14041 ttaaggagaa gcaagtagtc ggagagatag aaatcattcg tcccttcttg cattttcaga
    14101 aaaaagactt tccatcaatt tttcactttg aagatacatc aaatcaggag aatcattatt
    14161 ttcgaaatcg tattcgaaac tcttacttac cagaattgga aaaagaaaat cctcgattta
    14221 gggatgcaat cttaggcatc ggcaatgaaa ttttagatta tgatttggca atagctgaat
    14281 tatctaacaa tattgatgtg gaaaatttac agcagttatt ttcttactct gagtctacac
    14341 aaagagtttt acttcaaact tatctgaatc gttttccaga tttgaatctt acaaaagctc
    14401 agtttgctga agttcagcag attttaaaat ctaaaagcca gtatcgtcat ccgattaaaa
    14461 atggctatga attgataaaa gagtaccaac agtttcagat ttgtaaaatc agtccgcagg
    14521 ctgatgaaaa ggaagatgaa cttgtgttac actatcaaaa tcaggtagct tatcaaggat
    14581 atttattttc ttttggactt ccattagaag gtgaattaat tcaacaaata cctgtttcac
    14641 gtgaaacatc catacacatt cgtcatcgaa aaacaggaga tgttttgatt caaaatgggc
    14701 atagaaaaaa actcagacgt ttatttattg atttgaaaat ccctatggaa aagagaaact
    14761 ctgctcttat tattgagcaa tttggtgaaa ttgtctcaat tttgggaatt gcgaccaata
    14821 atttgagtaa aaaaacgaaa aatgatataa tgaacactgt actttatata gaaaaaatag
    14881 ataggtaaaa aatgttagaa aacgatatta aaaaagtcct cgtttcacac gatgaaatta
    14941 cagaagcagc taaaaaacta ggtgctcaat taactaaaga ctatgcagga aaaaatccaa
    15001 tcttagttgg gattttaaaa ggatctattc cttttatggc tgaattggtc aaacatattg
    15061 atacacatat tgaaatggac ttcatgatgg tttctagcta ccatggtgga acagcaagta
    15121 gtggtgttat caatattaaa caagatgtga ctcaagatat caaaggaaga catgttctat
    15181 ttgtagaaga tatcattgat acaggtcaaa ctttgaagaa tttgcgagat atgtttaaag
    15241 aaagagaagc agcttctgtt aaaattgcaa ccttgttgga taaaccagaa ggacgtgttg
    15301 tagaaattga ggcagactat acctgcttta ctatcccaaa tgagtttgta gtaggttatg
    15361 gtttagacta caaagaaaat tatcgtaatc ttccttatat tggagtattg aaagaggaag
    15421 tgtattcaaa ttagaaagaa taatctttaa tgaaaaaaca aaataatggt ttaattaaaa
    15481 atccttttct atggttatta tttatctttt tccttgtgac aggattccag tatttctatt
    15541 ctgggaataa ctcaggagga agtcagcaaa tcaactatac tgagttggta caagaaatta
    15601 ccgatggtaa tgtaaaagaa ttaacttacc aaccaaatgg tagtgttatc gaagtttctg
    15661 gtgtctataa aaatcctaaa acaagtaaag aaggaacagg tattcagttt ttcacgccat
    15721 ctgttactaa ggtagagaaa tttaccagca ctattcttcc tgcagatact accgtatcag
    15781 aattgcaaaa acttgctact gaccataaag cagaagtaac tgttaagcat gaaagttcaa
    15841 gtggtatatg gattaatcta ctcgtatcca ttgtgccatt tggaattcta ttcttcttcc
    15901 tattctctat gatgggaaat atgggaggag gcaatggccg taatccaatg agttttggac
    15961 gtagtaaggc taaagcagca aataaagaag atattaaagt aagattttca gatgttgctg
    16021 gagctgagga agaaaaacaa gaactagttg aagttgttga gttcttaaaa gatccaaaac
    16081 gattcacaaa acttggagcc cgtattccag caggtgttct tttggaggga cctccgggga
    16141 caggtaagac tttgcttgct aaggcagtcg ctggagaagc aggtgttcca ttctttagta
    16201 tctcaggttc tgactttgta gaaatgtttg tcggagttgg agctagtcgt gttcgctctc
    16261 tttttgagga tgccaaaaaa gcagcaccag ctatcatctt tatcgatgaa attgatgctg
    16321 ttggacgtca acgtggagtt ggtctcggcg gaggtaatga cgaacgtgaa caaaccttga
    16381 accaactttt gattgagatg gatggttttg agggaaatga agggattatc gtcatcgctg
    16441 cgacaaaccg ttcagatgta cttgatcctg cccttttgcg tccaggacgt tttgatagaa
    16501 aagtattggt tggccgtcct gatgttaaag gtcgtgaagc aatcttgaaa gttcacgcta
    16561 agaacaagcc tttagcagaa gatgttgatt tgaaattagt ggctcaacaa actccaggct
    16621 ttgttggtgc tgatttagag aatgtcttga atgaagcagc tttagttgct gctcgtcgca
    16681 ataaatcgat aattgatgct tcagatattg atgaagcaga agatagagtt attgctggac
    16741 cttctaagaa agataagaca gtttcacaaa aagaacgaga attggttgct taccatgagg
    16801 caggacatac cattgttggt ctagtcttgt cgaatgctcg cgttgtccat aaggttacaa
    16861 ttgtaccacg cggccgtgca ggcggataca tgattgcact tcctaaagag gatcaaatgc
    16921 ttctatctaa agaagatatg aaagagcaat tggctggctt aatgggtgga cgtgtagctg
    16981 aagaaattat ctttaatgtc caaactacag gagcttcaaa cgactttgaa caagcgacac
    17041 aaatggcacg tgcaatggtt acagagtacg gtatgagtga aaaacttggc ccagtacaat
    17101 atgaaggaaa ccatgctatg tttggtgcac agaatcctca aaaatcaatt tcagaacaaa
    17161 cagcttatga aattgatgaa gaggttcgtt cattattaaa tgaggcacga aataaagctg
    17221 ctgaaattat tcagtcaaat cgtgaaactc acaagttaat tgcagaagca ttattgaaat
    17281 acgaaacatt ggatagtaca caaattaaag ctctttacga aacaggaaag atgcctgaag
    17341 cagtagaaga ggaatctcat gcactatcct atgatgaagt aaagtcaaaa atgaatgacg
    17401 aaa
//
LOCUS       DAVLBN010000046        17179 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLBN010000046 DAVLBN010000000
VERSION     DAVLBN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.046"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            314..1360
                     /gene="pheS"
                     /locus_tag="VXC24_001537"
     CDS             314..1360
                     /gene="pheS"
                     /locus_tag="VXC24_001537"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0493632.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDVTVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1360..1869
                     /locus_tag="VXC24_001538"
     CDS             1360..1869
                     /locus_tag="VXC24_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493633.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1946..4351
                     /locus_tag="VXC24_001539"
     CDS             1946..4351
                     /locus_tag="VXC24_001539"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0493634.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4419..5420)
                     /locus_tag="VXC24_001540"
     CDS             complement(4419..5420)
                     /locus_tag="VXC24_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0493635.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRVKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPGTVIVKKSYGFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5576..6064
                     /locus_tag="VXC24_001541"
                     /pseudo
     CDS             5576..6064
                     /locus_tag="VXC24_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6149..6415
                     /locus_tag="VXC24_001542"
     CDS             6149..6415
                     /locus_tag="VXC24_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493636.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            6675..8924
                     /gene="metE"
                     /locus_tag="VXC24_001543"
     CDS             6675..8924
                     /gene="metE"
                     /locus_tag="VXC24_001543"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0493637.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGMKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8988..9854
                     /gene="metF"
                     /locus_tag="VXC24_001544"
     CDS             8988..9854
                     /gene="metF"
                     /locus_tag="VXC24_001544"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0493638.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10539..12752
                     /gene="pnp"
                     /locus_tag="VXC24_001545"
     CDS             10539..12752
                     /gene="pnp"
                     /locus_tag="VXC24_001545"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0493639.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12768..13385
                     /gene="cysE"
                     /locus_tag="VXC24_001546"
     CDS             12768..13385
                     /gene="cysE"
                     /locus_tag="VXC24_001546"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0493640.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13397..14281
                     /locus_tag="VXC24_001547"
     CDS             13397..14281
                     /locus_tag="VXC24_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493641.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14368..15711
                     /locus_tag="VXC24_001548"
     CDS             14368..15711
                     /locus_tag="VXC24_001548"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0493642.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAVMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15704..16090
                     /locus_tag="VXC24_001549"
     CDS             15704..16090
                     /locus_tag="VXC24_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0493643.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16094..16978
                     /locus_tag="VXC24_001550"
     CDS             16094..16978
                     /locus_tag="VXC24_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0493644.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(17058..>17179)
                     /locus_tag="VXC24_001551"
     CDS             complement(17058..>17179)
                     /locus_tag="VXC24_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0493645.1"
                     /translation="IKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5096 a         3358 c         3927 g         4798 t
ORIGIN      
        1 gctataaagt tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg
       61 gtaaaaatct gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag
      121 ggaagtatat cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat
      181 tcacttgcgc atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc
      241 gcgtgtcaac gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac
      301 tgatggagga aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct
      361 ggctagcttg aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc
      421 tgtccttggt aaaaagggtt cgctcactga aatcctcaaa gggatgaaag atgtttctgc
      481 tgagatgcgt ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgactgctgc
      541 ttttgaagaa acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga
      601 gagtatcgat gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac
      661 acaaaccagt gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg
      721 ttttgaagtg gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc
      781 agctcgtgat atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac
      841 gtctccagtt caggcgcgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat
      901 gatctcgcca gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt
      961 ccaccaaatc gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac
     1021 gcttcagttg attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc
     1081 ttacttccca ttcacagagc catctgttga ggtggatgtt tcttgcttca agtgtggtgg
     1141 agaaggctgt aatgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt
     1201 tcacccacgt gtccttgaaa tgagtggtat cgatgtgact gtatactctg gctttgcctt
     1261 tggtcttgga caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt
     1321 ctaccaagga gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg
     1381 gcagatgttg aggtgttggc taaaattgcc aaacaagcct ttcgtgaaac ctttgcgtat
     1441 gataatacgg aagagcagtt acaggaatac tttgaagagg cttatagtct gaaaactttg
     1501 tcaactgagt tgggaaatcc tgactctgaa acctatttca ttatgcatga ggaggagata
     1561 gctggttttc tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct
     1621 tttgaaattc aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa
     1681 ctgtttgaat tcgcacttga acttgctaca aaaaatagtt tttcttgggc ttggttaggt
     1741 gtttgggagc ataatacaaa agctcaagcg ttttataatc gatatggttt tgaaaaattt
     1801 agccaacatc attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa
     1861 ttaaggtaag aagaggattc ttctattgaa atgataggaa aggaaaagaa ctagagtgac
     1921 aactgtcatt ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt
     1981 ggacattgat gtgccatcac aagagttggc tgaaaaaatg tcaactacag gaatcgaggt
     2041 agagggtgtc gaatcaccag ctgctggtct ctcaaaaatt gtcgtcggtg aggtcttgtc
     2101 ttgcgaagat gtgccagaga ctcacctcca tgtttgtcag gttaacgttg gcgaagaaga
     2161 agagcgtcag atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc
     2221 tcttccagga gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt
     2281 ggagtcactt ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc
     2341 taaggaattc gcagatggca tccaaatctt gccagaaaat gccgtgccag gtgaggaagt
     2401 cttttcttac ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc
     2461 agatgccctt tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt
     2521 caactttaaa gaatttactc taacagaaac taatgaatct gcggcagatg ccctttctgt
     2581 cagcattggg acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat
     2641 cgcaccaagt ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa
     2701 taacgttgta gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt
     2761 tgacttggac acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg ctggtgaaaa
     2821 gttggtgacc ttggacggtg aagaacgaga cttggctgag acagacctcg tgattacagt
     2881 tgctgacaaa ccagtagccc ttgccggtgt tatgggtggt caggctacag aaatttctga
     2941 aaaatctagt cgtgttatcc ttgaagctgc tgtttttaat ggcaaatcta tccgtaagac
     3001 aagtggtcgc ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt
     3061 ggcaacagtt aatgaagccc ttgatgcggc agctagcctg attgcggaac ttgcaggtgc
     3121 gacggtgcgt aagggtatcg tttcagcggg tgagcttgat acttcagatg tagaagtttc
     3181 ttcaactctt gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtcga
     3241 agacgtcttc cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag
     3301 cgtaccacgt cgtcgttggg atatcacaat cgaagctgat ctctttgaag aaatcgctcg
     3361 tatctatgga tatgaccgtt tgccaaccag ccttccaaaa gacgatggta cagctggtga
     3421 attgactgtg acacaaaaac tccgccgtca agttcgtacc attgctgaag gagcaggttt
     3481 gacagaaatc atcacctata ctctaacaac tcctgaaaaa gcagttgagt ttacggctca
     3541 accaagtaac cttacggaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca
     3601 aaatatgatt tcaggtatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa
     3661 cttggccctt tacgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact
     3721 tccaaatgaa atcaacagtt ttgcctttgc cttgacaggc ttggttgctg aaaaagattt
     3781 ccaaacagca gcagttccag ttgatttctt ctatgctaag ggaatccttg aagcgctctt
     3841 tactcgcttg ggactagaag tgacctatac agcaacagct gagattgcca gccttcaccc
     3901 aggacgtaca gcagtcattt cactcggtga ccaagttctt ggttttcttg gccaagtgca
     3961 tccagtcact gccaaggctt acgatattcc agaaacgtat gtagctgagc ttaacctttc
     4021 agccatcgaa ggggcgctcc aacctgctgt tccatttgtg gaaatcacga aattcccagc
     4081 agtcagccgt gacgttgccc ttctcctcaa ggcagaagta actcaccaag aagttgtaga
     4141 tgctatccaa gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc
     4201 aggtgagaaa ttgggacttg gtatgaagtc catggcttat agcttgacct tccaaaatcc
     4261 agaagatagc ttaacggacg aagaagtcgc acgctatatg gaaaaaatcc aagcatcgct
     4321 cgaagaaaaa gtgaatgcag aagtgcgtta aacgatagta ggatataaat tccccctcta
     4381 gtttatgaac actagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa
     4441 atacatctat gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg
     4501 tttttaggca ataaaatatg atctatcgtt gcattaaaaa gttttggact ttggctattc
     4561 caagttcctc tttcaaaagg tggcagtgca tttaatgcgt ccctatgaga gcttattttt
     4621 gcaagtgctc catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat
     4681 tttgaagcca attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct
     4741 ggcagaggag gagcagtatg caaagcaatg atatctggta tatcttgttt tctcgaatgt
     4801 aatacaattg tcccgaaccg tgttgtatga aaagtttcag cttttgtata gaaaccataa
     4861 cttttcttga caatcacagt cccaggagct attccactat tggtaggtgg agaagtgaaa
     4921 atatcatagt tggccataga aagtccaact tgatgaaaca atagtttgac tctctggttt
     4981 tcttgctcac ctctgatatt ggtagctagt tcagggaata tagccatatc ggcgtcaaaa
     5041 tggctaaaaa ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact
     5101 aattttaagg ttttagtctt atttgatgca gaagaaaggg ttttatctgt tccaaataat
     5161 agtaatatga gcgatagtaa gagcaaaatg ccagagtaaa accgtatttg tttatttttc
     5221 ttgtaaaaag ataggaaaaa aaataagaaa cttaaaatag cagccatagt tgcagtagct
     5281 aaggggaagg cataaatctg tgccaagata ggttgggtag atagccaaat gttaagatta
     5341 gaagatggga aaaaagaata agttatgata gggatagaaa agagaatgac cgaaagggca
     5401 gagagaaatg ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa
     5461 tgtgactttg tgactttact tgattgatat tctttttctt gtcttcctca tagattaagt
     5521 acaacccaag taaaaaaagt ccaatttaag attgaaatga ttaaaaggca cagaaatgca
     5581 agacaattat actacaaaag gcaaacattt gacaatcgat agccgtcgct taatcgaacg
     5641 atggaaaaaa gaaggaaaat caaatagaga aattgcctct ctacttggaa aaactcctca
     5701 aactatccat actgaaatca agtatgggac agtccgaaaa tgtcttggaa aagggcgctt
     5761 caaagagatt tattctgcca actatgctca acagtcttat gaaaataatc gcaagcactc
     5821 ggtcaagaga tcaagcttga ccaaggaact aaaggaaaag attctccact atcataacca
     5881 aaaatttttg cctgaaatga tggtgatggc taaaggggtt aacgtgggaa tttcaaccat
     5941 ttactattgg attcatcatg gaaagttggg gttaagcaaa caggatttgc tttatcctag
     6001 aaaaggaaaa tcgcttaaga aacaagttag tcccaatttt aaacccgctg atcaatctat
     6061 cgaatcataa ttcgctcatt ttttcaaaaa atacatagat ctaaaagaaa gaggggtaag
     6121 tgatgaagaa tagtgctatt gggagtaatt ggaaggatgt ccatctgagc tctttagcaa
     6181 ggaggaaatc cttgaaagtg atatgcgagt agctatcatg agcgagttga ttgaagccag
     6241 aaataagcaa ggaatcagtc agaaaaagct agaggaactc agtggagtga gtcagcctgt
     6301 tatagctagg atggagacag gtaagactag tccacagttg gacacagtct taaaagtcct
     6361 agctagtcta ggaaagacac tagcagtcgt tccacttgaa caggggaaaa gttgactaga
     6421 atcagttata gtcttttcta ataacaagcc atagtcactt ataagaatta ctaataacgc
     6481 gtttgagcat tctaactaaa atacagctaa aaacaagtta taaaagggat ttgagacgtt
     6541 tgcttcaagt ctttttcttt tgtccgaaac agatatatag tttcaaacta tatcaaaccc
     6601 taatttttta caattataca gacgctttct tttctgttaa gatagtttca acaacaaatt
     6661 ttggaggaca catcatgtca actacaatca tcggtttccc tcgtttgggc gaattccgcg
     6721 aattaaaatt tacaactgaa aaatacttta gaaaagaaat ctcagaagaa gaactccttg
     6781 cagccgcaaa agacttgcgt gctaaacact ggaacatcgt caaagaaaaa ggcatcactg
     6841 aaatcccatc aaatgacttt tctcactatg acaacttcct agatgcggct ttccttttca
     6901 acgtggtgcc tgcctcagtt caaaacttgg acttgtctga ccttgagcgc tacttcgctt
     6961 tgggacgtgg ttaccaggga gaaaaagggg acgttcgcgc ccttccaatg aagaaatggt
     7021 tcaacactaa ctaccactac atcgttccta aatttgaaaa agacactcaa gtgaaattgg
     7081 ctggtcacaa gatttttgat gagttccaag aagccaaaga acttggattg aacactcgtc
     7141 ctgttcttgt aggtcccttc actttccttc aattgtcaga ctttgaagaa ggcatgaaag
     7201 cagacgactt cgtagatagc ttagtggctg cttaccaaga agtttttgct aaattggctg
     7261 aacttggtgc gacttgcatc caattggatg aagcggctct tgtaaaagac ttgacagctg
     7321 aagaaaaagc tctcttcttg aacctttaca acaaactctt ggctgacaaa aaaggtcttg
     7381 aagtcttgct tcaaacttat ttcggtgatg ttcgtgacgt ctacgctgac cttgtaaact
     7441 tgccagtaga tgctatcggt cttgactttg ttgaaggtaa gaaaactctt gaactcgtta
     7501 aaggtggctt cccagctgac aagactctct atgcaggtat tgtcaatggt aaaaacatct
     7561 ggcgcaacaa ctacgaaaag agcttggctg ttcttgagca aatcccagct gaaaacatcg
     7621 ttttgacaag ctcttgctca cttcttcatg tgccatttac aactgctaat gaagaatttg
     7681 aaccagcact cttgaaccac tttgcctttg cagttgaaaa attggatgaa atccgtgact
     7741 tggatgctat ccgcaatggt caaggttcag aagctcttgc agccaacaaa gaactctttg
     7801 cgactgagcg tgttggtgaa aatgctgaac ttcgtgcgcg tatcgctggc ttgacagacg
     7861 cagactacac tcgtttgcca gcctttgcag aacgtgaagc tatccaagaa gaagctttca
     7921 aacttccagc tcttccaaca acaacgattg gttcattccc tcaaacaaaa gaagttcgtg
     7981 ccaaacgttt ggcttaccgt aaaggtgaat tgtctcaaaa agagtacgac gctttccttg
     8041 ctgaaacgat tgacgaatgg atcaagtggc aagaagatat tgactttgat gtccttgttc
     8101 acggtgaatt tgagcgtaat gacatggttg agtacttcgg tcaaaacttg tcaggttacc
     8161 tcttctctaa aaatggttgg gtacagtcat acggtatgcg tggggtgaaa ccaccaatca
     8221 tctggggtga tgtcactcgt cttaacccta tcactgttaa atggtctagc tatgcacaaa
     8281 gccgtacaaa caaacctgtt aaaggtatgt tgactggacc tgttaccatc ctcaactggt
     8341 cattcccacg tgaagacatc tctatcaagg attcaactct tcaaatcgcc cttgctatca
     8401 aggatgaagt gcttgacctt gaagctgctg gtgtgaaaat catccaaatt gatgaggctg
     8461 ctcttcgtga aaaattgcca ctccgccgta gcgactggta cgaagactac cttgactggg
     8521 ctattcctgc cttccgcttg gtacactcaa cagtagcgcc agacacacaa atccacactc
     8581 acatgtgtta ctcagaattt acagatatca tcccagctat cgataacatg gatgcagacg
     8641 ttatttcctt tgaagctagc cgttcaaacc ttgaaatctt ggacgaactc aaagcgaaaa
     8701 acttccaaac agaagtggga cctggggttt acgatatcca ctcacctcgt gtaccaaatg
     8761 aaggcgaaat cgacaacaca atcgaagcca tccttgctaa agtgccaagc aagaaagttt
     8821 ggatcaaccc tgactgtggt ttgaaaacac gtggtatccc agaaacaaaa gaaagcttga
     8881 tccgccttgt tgaagcagct aaagctgcgc gtgagaaatt gtaagattgg atttctctcc
     8941 atacagtggt tgttcaaaaa gaaatcaact agaaaaggtt attacatatg tcacgccaaa
     9001 caccgtcact ctcatttgaa gtgttccctc caaacccagc cgtgggtaat gataacatta
     9061 tttcagcctt gcaggatatg caggagttgg ttccccattt tatcagtgta actgccagca
     9121 ataataaatt taatatcaag gaaacgacgg ttcgtttggc tgactttatc caaaatgatt
     9181 tggcgattcc gaccattgcc cacttgccag ctatttatct aactaaggac aaggttgctg
     9241 aaactattgc tgacttggac aaagttgggg tgcagaaaat cttggctctt cgtggggata
     9301 ttattccaga cgtggaacca caaaaggatt tccgctatgc aaccgacttg attgagttta
     9361 tcaaggaacg agcccctcac tttgatatta ttggagcttg ctatccagaa gggcatccag
     9421 attcgccaaa tcagatttca gatattcaaa atcttaagaa gaaagtggat gcaggctgtt
     9481 cgagcctcgt aactcagctc ttctttgaca atgagcgctt ctatgatttt caggacaagt
     9541 gtatcttggc tgggattgat gttcccattc atgcaggaat tatgccaatt ctgaatcgaa
     9601 atcaggctct ccgactcttg aagacttgtg agaatatcca tcttccacgc aaatttaaag
     9661 ccatcttaga caagtatgag catgaccctg agtcgctcag agcagcagga cttgcctatg
     9721 cagtggacca aatcgtggac ttggtaactc aggatgttgc cggtgtgcat ctctatacga
     9781 tgaataatgc tgatacagca aaatacatcc atcaagcaac ccatgccttg tttaatcacc
     9841 agtctctagg ataataaaag caaaccattc ttctcaggtg aggggaatgg ttccttttta
     9901 atggtaaaga cctcactttt taagaaaaat atgataaaat aaattctgta cgtacttgat
     9961 acaaagatga aggtattaaa taatacaatg catttaaact gtaagattta acgacacgag
    10021 tgagtcaaat cgatgttatt tgacgagaga gttagtaaag catttagcta atcgcccgat
    10081 agcgattagc gtgaaagctt tagatacttt agtattaaac ctttctaatg atgtatcttg
    10141 aaaactgaac ttgcctacaa ctctgtggaa aaagataaat ctccctagga gtagtcgctc
    10201 cgtcgttcga tttcctatct tcctttgagt tgcttgacgg cttggtatct tgatgacttg
    10261 aattttggtc tcatttctta ggaaaaaaga taagcttcct agcactcgtc gagtgtgacg
    10321 tcaccttcct atttttctac agaaatgttc ggcaagccga accgtccaaa atatcttgtg
    10381 taattgaaca cggccgaaaa gctgtgtaaa aaagataaac tgtcttgtct tcatcgaaga
    10441 cttcgtcagt ttcctatttt tactttgctt ttgacgtcct tggtatcttg atctttgtag
    10501 gcaaggcgta taatttcatc aatccaaagg ggattaaaat ggcaaaacaa gtgtttcaaa
    10561 cgacttttgc gggtcgtgag ttaattgtag aaactggtca ggttgctaag caagcaaatg
    10621 gctctgttgt cgtacgttac ggtgagtcaa ctgtcttgac tgctgccgtt atgtctaaga
    10681 aaatggcaac tggggatttc ttcccactcc aagtcaacta cgaagaaaaa atgtatgcgg
    10741 ctgggaagtt tcctggtggc tttatgaaac gtgaaggacg tccttcaaca gatgcgacct
    10801 tgacagcgcg tttgattgac cgtccgattc gtcctatgtt tgcggaaggt ttccgtaatg
    10861 aagtccaagt catcaataca gtgctttctt atgatgaaaa tgcatctgca ccaatggctg
    10921 ctatgtttgg ttcatctttg gcactgtcta tttcagatat tccatttgac ggaccaattg
    10981 ctggggtaca agtgggatat gtagatggcc aaatcatcat caacccaagt caagaacaag
    11041 cagagcaatc tcttcttgaa ttgacagtag ctggaaccaa gcacgctatc aacatggtag
    11101 agtctggtgc caaagaattg tcagaagaaa tcatgttgga agcgcttctt aaagggcacg
    11161 aagctgtcaa agaattgatt gccttccaag aagaaatcgt tgctgctgtc ggtaaagaaa
    11221 aagcagaagt ggaattgctt cacgtggatg ctgaattgca agctgaaatc attgcagcct
    11281 acaacagtga cctccaaaag gcagttcaag tagaagagaa attggcccgt gaagctgcaa
    11341 ctcaagcagt gaaagaccaa gtgactgccg tttacgaaga aaaatatgcg aaccacgaag
    11401 aatttgaccg tattatgcgt gatgtggctg aaatcttgga acaaatggaa cacgcagaag
    11461 tgcgacgttt aattacagaa gacaaggtgc gtcctgatgg tcgtaaggtc gatgaaatcc
    11521 gtcctttgga tgcggttgtt gacttccttc ctcgtgtaca tggttcaggt ctctttactc
    11581 gtgggcaaac tcaagctctt tcagtcttga ccttggctcc gatgggagaa actcaaatca
    11641 ttgatggttt ggatccagag tacaagaaac gctttatgca ccactataac ttccctcaat
    11701 attctgtagg ggaaacaggt cgttacggtg cgccaggtcg tcgtgaaatc ggtcacggtg
    11761 cccttggtga gcgtgctctt gctcaagtct tgccaagctt ggaagaattc ccatacgcta
    11821 tccgtctagt agcagaagtt ttggaatcaa acggttcttc atctcaagct tctatctgtg
    11881 cgggaactct tgcccttatg actggtggtg tgccaatcaa ggcgccagta gctggtattg
    11941 ctatgggact tatctcagat ggaaataact acacagtatt gacagatatc caaggtttgg
    12001 aagatcactt tggagatatg gacttcaagg ttgcaggtac tcgtgatggg attacagccc
    12061 ttcaaatgga tatcaagatt caagggatta ctgcagaaat cttgacggag gctcttgctc
    12121 aagccaagaa agcgcgtttt gaaatccttg atgtcattga agcaaccatt ccagaagttc
    12181 gtccagaatt ggctccaact gctccgaaaa ttgatacgat caagattgat gtggacaaga
    12241 ttaagattgt catcggtaag ggtggagaaa ccatcgacaa gattatcgct gaaacaggtg
    12301 ttaagattga tatagacgaa gaaggaaatg tgtctatcta ctctagtgac caagatgcta
    12361 ttaaccgtgc caaagaaatt attgctggtt tggttcgtga agccaaagtg gatgaagttt
    12421 accgtgctaa agtcgttcgt atcgagaaat ttggtgcctt tgttaacctc tttgataaga
    12481 cagatgccct tgttcatatc tctgagatgg cttggactcg taccaatcgt gtagaggatt
    12541 tggtagaaat cggggatgaa gttgatgtta aggttatcaa gattgatgaa aaaggccgta
    12601 tcgatgcctc tatgaaggct cttctacctc gtccgccaaa acctgagcat gatgaaaaag
    12661 gtgaaaagtc tgagcgccct caccgcccac gtcatcacaa ggatcacaaa cctaagaaag
    12721 aatttacaga aacaccaaaa gattcagagt aagaaaagga gaaatgtatg gggtggtggc
    12781 acgaaaccat tgatatcgta aaagaaaatg atccagcggc ccgcaccact ttggaggttt
    12841 tgctgactta tccaggtgtc aaggccttgg cggcccaccg tctctcgcat tttctctgga
    12901 agtacgactt caaactctta gctcgtatgc acagtcagtt ttggcgcttt tggactcaga
    12961 ttgagattca tccaggagcc cagattgatt caggtgtctt tattgaccat ggttctggtc
    13021 tggtgattgg agagacagcg attgttgaaa aaggcgttct tctctatcac ggagtgactc
    13081 tcgggggaac agggaaagac tgtggcaaac gccatccgac tgtacgaaag ggagccctca
    13141 tatcagccca tgcccaagtt atcgggcctg tggaaattgg tgaaaatgcc aaggtcggtg
    13201 ctgcagcagt tgtcgtagca gatgtaccta gtgatgtgac ggttgtcggt attccggcca
    13261 agattgtccg tcttcatggt aagaaagatg agcctgttat tcacgaagtc gaagaaaaac
    13321 gggagtatta tgtcaataaa ctcgagcagg ctaaagatgc cagtcacaga tcgtctggtt
    13381 tgtagaggat acctatatga ttcaagcaag aaacaagtta agccaagagg agctatctga
    13441 ggcgaaaaaa gtaattaact gttgccaaaa ctatgacggt acctatcgcg atccctatct
    13501 ctctaacatg cttaattttg acccaaacat gcccgccttt ttcctttatt atgaaaaagg
    13561 caaacttgtt ggtttattaa ctgtctatgc agatgaccaa gatgtagaag tgacgatact
    13621 ggttcatcca ggtcatcgcc gtcaggggat tgcgcgtgca ttgtttacta gttttgagag
    13681 agaaacagct tctttcccca ttcgatcagt cacttttcag acagaacgta tttttttaga
    13741 gaatcatcct gactttgcca gtaactgggg actaatcgag gatgaagaga cagaaacttg
    13801 gttaggtaag gatagaagac cttatccgtt agcaaatgtt tcccatcttg aagttttgtt
    13861 agcagatagt tcgtatcagg atcaaattag tcaattaaaa tttcaggcat tttcagagga
    13921 acatgaatcg agagaagttg tggatagata tgtcgctgaa gctctgaaag atccagaaag
    13981 ccgactatat attttattaa aagctggtca ggttattggg acttgcacgg ttgatttatc
    14041 gagcgatacg aattacttct acggtttagc aatatcagaa cctgaacgtg ggaaaggcta
    14101 tggaagctac ttagcaaaat cccttgtcaa ccaactaatt gagcaaaatg acaaggaatt
    14161 tcagattgca gtggaagata gcaatgtagg tgccaaacgt ttgtatgaaa aaattggctt
    14221 tgtcaaacag acacaggtgg tttatctgaa tgagaaagga gcaagggatt ccgaagtgta
    14281 gagacattcg gactgaaatt tacttgagct cttagtttag tgatgaaact aattgttctt
    14341 ggatttcagc tttcctgatt atgatttatg attaaaatct atgacaccat gtctcgtgat
    14401 ttgcgagaat ttgtcccgat tgaggacggc aagatcaaga tgtatgtttg tgggccaacc
    14461 gtgtacaact atatccacgt gggaaacgcc cgttcgacgg tagcttttga tacgattcgt
    14521 cgctattttg agtaccgtgg gtataaggtt gcctatattt ccaattttac agatgtggat
    14581 gataagatta tcaaccgtgc cagggaagaa ggtatcacgc ctcaggaggt tgcggataag
    14641 tacatcgctg cctttcgtga ggatgtgacg gcattaggcg tgaaacctgc gactcgccat
    14701 ccgcgtgtag tggagtttat ggcagacatc atccgttttg tggaagactt gatcgagaaa
    14761 ggctttgcct atgagagtca aggggatgtc tatttccgtg tagaaaaatc ccacaactat
    14821 gctaaattgg ctaataaaac cttggaagat ttggatctag gtgcttcagg tcgtaccgat
    14881 gaagaaacgg ctcgtaagga aaatcctgta gattttgctc tatggaaatc ttccaaacca
    14941 ggtgagattt cttgggatag tccttgggga cctggacgtc cgggttggca tattgagtgt
    15001 tcagtcatgt cgacagagat tttaggtgat accattgata tccacggtgg tggagctgac
    15061 ctagagtttc cacaccacac caatgaaatt gcccaatctg aagctaaaac aggcaaggct
    15121 tttgctaact actggatgca caatggcttt gtcaatatcg acaatgtcaa aatgtctaag
    15181 tccttgggta acttcattac ggtacacgat gcccttaaaa ctcttgatgg gcaagtactt
    15241 cgtttcttct ttgcgaccca gcactaccgt aagcctatca acttcacgga aaaggcagtt
    15301 cgcgatgccg agaccaatct caagtatctg aagaatactt acgaacaacc atttacagga
    15361 aacgtggatg cccaagagtt acaaaacttt aaagataagt ttgtagcagt tatggatgaa
    15421 gattttaatg ctgccaacgg tatcacagtt gtctttgaaa tggccaaatg gatcaattca
    15481 gggaactatg atgcaagtgt caagcaagct cttgcagata tgttagaaat ttttggaatt
    15541 gtctttgttg aggaagtttt ggatgcagag attgaagact tgattcaaaa acgccaagag
    15601 gcgcgtgcca atcgtgactt tgcgacagca gaccaaatcc gtgaccaatt ggttactcaa
    15661 ggaattaagc tccttgatac caaggatgga gtgaggtgga cacgtgattg atgtcaatct
    15721 cattaacggg attgcgctag cctttgaggg ggatgcggtg tattctatgt atattcgccg
    15781 tcacctcatc ctcaaaggta tgaccaaacc caataaactc catcaagaag caaccaagta
    15841 tgtgtcagcc aaggctcagg ctcgcctgat tgctctcatg ttggaggagc aggtcctaac
    15901 ggaaaaagaa gaagaaatct acaaacgtgg ccgcaatacc aatagccaca caaaggctaa
    15961 aaatgcagat gtcgtgactt atcgtatgtc cacgggattt gaagcggtta tgggctatct
    16021 ccatatgact gagaatctgg aacgtcttga gagtttggtt tcatggtgca tccaaaaagt
    16081 ggagggctag aacatgaggg caaaagaact acaagactgg tttcctgagg ctcggatttc
    16141 agaccaacca gtagagaaag agggctatct cacgctccct ttagcttctc agcagtggat
    16201 tttgctggag gaagctgggc tcagcgagcg tgaaaagcag ttggttgccc ttttgaccca
    16261 gcaggagcag gctcgttcgc taaacccttg gtattcctat ctggttgaag gcaagggaca
    16321 ggcaccgcaa gtttttaaaa agattcagtt ggtttattgc catctttctt attttcagca
    16381 ggaaaatctg gcttcttggc tagatatgat gcggactctt tttccgaatt gtcagacagt
    16441 gttacaggtc ggagctcagg attatgtttt cgtgcttcaa caagacaaat acacttctgt
    16501 aagagatatt ttaagtgata tgattgaagc agttgagtat gactttggac ttcgtctttc
    16561 tatcatgttg ggtcaggttt ggtctcagac aggacatcaa gccctatcag acttaatcaa
    16621 agctgagcgg gatttgttca agacatggtg gcgtcagggt caccaaggtg ttcatacttt
    16681 ttctcagctc tatctttgga gtatgggaga aagactcgtg gacttgaagc caattaaaga
    16741 atgtctacac cagatgattt tggatcaaga tcagattcag gaaatcattc tctctctttg
    16801 ggaaaatagt gctgttctca ctaaaacagc ccagcaactc tatctgcacc gcaattctct
    16861 ccaatacaag attgataaat gggaagagtt gacagggctt cagttgaaag agttgaccga
    16921 cctgaccttg tgttatcaat tgattttagg ttctttgtca actatagttg gtttgtaaag
    16981 aagttaatat ttggagaaga ggatggccat cttctccatt ttatggctct ttgtcaactg
    17041 tagtgggttg aagtcagcta agctcgagaa aggacaaatt tcgtcctttc ttttttgata
    17101 ttcagggcga taaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg
    17161 cgcttgataa gtttgatga
//
LOCUS       DAVLBN010000047        16801 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLBN010000047 DAVLBN010000000
VERSION     DAVLBN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.047"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1133
                     /locus_tag="VXC24_001552"
                     /pseudo
     CDS             1..1133
                     /locus_tag="VXC24_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VXC24_001553"
     CDS             complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VXC24_001553"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0493646.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3025..3723
                     /locus_tag="VXC24_001554"
     CDS             3025..3723
                     /locus_tag="VXC24_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0493647.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3766..4662)
                     /locus_tag="VXC24_001555"
     CDS             complement(3766..4662)
                     /locus_tag="VXC24_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0493648.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4671..5606)
                     /locus_tag="VXC24_001556"
     CDS             complement(4671..5606)
                     /locus_tag="VXC24_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0493649.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5603..6328)
                     /locus_tag="VXC24_001557"
     CDS             complement(5603..6328)
                     /locus_tag="VXC24_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0493650.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(6412..7047)
                     /locus_tag="VXC24_001558"
     CDS             complement(6412..7047)
                     /locus_tag="VXC24_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0493651.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7049..7876)
                     /locus_tag="VXC24_001559"
     CDS             complement(7049..7876)
                     /locus_tag="VXC24_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0493652.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7898..8233)
                     /locus_tag="VXC24_001560"
     CDS             complement(7898..8233)
                     /locus_tag="VXC24_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0493653.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(8234..8950)
                     /locus_tag="VXC24_001561"
     CDS             complement(8234..8950)
                     /locus_tag="VXC24_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0493654.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHL
                     YVVEPSETIEKDGDKKLIVY"
     gene            complement(9093..9284)
                     /locus_tag="VXC24_001562"
     CDS             complement(9093..9284)
                     /locus_tag="VXC24_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493655.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIASGAIRDLWRYSC"
     gene            9473..10084
                     /locus_tag="VXC24_001563"
     CDS             9473..10084
                     /locus_tag="VXC24_001563"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0493656.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10129..10857
                     /gene="rlmB"
                     /locus_tag="VXC24_001564"
     CDS             10129..10857
                     /gene="rlmB"
                     /locus_tag="VXC24_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0493657.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VXC24_001565"
     CDS             complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VXC24_001565"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0493658.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11873..12097)
                     /locus_tag="VXC24_001566"
     CDS             complement(11873..12097)
                     /locus_tag="VXC24_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0493659.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12175..12918)
                     /locus_tag="VXC24_001567"
     CDS             complement(12175..12918)
                     /locus_tag="VXC24_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0493660.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12918..13718)
                     /locus_tag="VXC24_001568"
     CDS             complement(12918..13718)
                     /locus_tag="VXC24_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0493661.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13876..14232)
                     /locus_tag="VXC24_001569"
     CDS             complement(13876..14232)
                     /locus_tag="VXC24_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0493662.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14226..14756)
                     /locus_tag="VXC24_001570"
     CDS             complement(14226..14756)
                     /locus_tag="VXC24_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0493663.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(14756..15250)
                     /locus_tag="VXC24_001571"
     CDS             complement(14756..15250)
                     /locus_tag="VXC24_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493664.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15385..15831
                     /locus_tag="VXC24_001572"
     CDS             15385..15831
                     /locus_tag="VXC24_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0493665.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15828..16475
                     /locus_tag="VXC24_001573"
     CDS             15828..16475
                     /locus_tag="VXC24_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0493666.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         5058 a         3790 c         2972 g         4981 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgccttcta gaattctcct tagaaaacgc
       61 cgtttcaagt gctatcactg ttcaaaaatg atggttgctg agactcccct ggtaaagaag
      121 aatcaccaaa tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgattttc actttaaaca tgatttttcg cgtcttcctg agattatgtc ttgggatgag
      301 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttgaaaa gctcgatatc
      361 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
      421 agagttgtcc gatgtcgcgt caaaattatt actatggata tgtttagccc ttactatgac
      481 ttagctagac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
      541 tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtgcaa catcttagcc
      601 gtgctatgag tcgtgtgcat gttcaaatca tgaatcagtt tcatcgaaaa tcccatgaat
      661 acaaggctat caagcgctac tggaagctca tacaacagga tagccgtaaa ctgagtgata
      721 agcgttttta tcgtcctact tttcgtatgc atttaaccaa taaagagatt ttagacaagc
      781 ttttgagcta ttcggaagac ttgaaacacc actatcagct ctatcagctc ttgctttttc
      841 acttccagaa taaggaacca gagaaatttt tcggacttat tgaggacaat ctgaagcagg
      901 ttcatcctat ttttcagact gtctttaaaa ccttcctcaa agataaagaa aagattatca
      961 acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat ctcatcaaac
     1021 ttatcaagca caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
     1081 tcgctctgaa tatcaaaaaa gaaaggacga aatttgtcct ttctcgatct tagcttttct
     1141 tcaacccact acagttgaca aagagcctga aaactacggt ctaatttttt gtccaaatgt
     1201 aaaccacttg gaactattat tcaatttatt ctttttagca aatgttcccg ttttaatccc
     1261 agttacagtt tttaatcctt tgtaaccgtt gattttacaa agcttttaat ttttttgcga
     1321 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
     1381 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
     1441 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
     1501 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
     1561 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     1621 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     1681 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     1741 agcacgaact tcatccttgt aaagagtatt gagtggttca atcaattcaa actgcatatc
     1801 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     1861 ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     1921 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     1981 gtcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     2041 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     2101 accgtggtcc acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     2161 aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat caccgacggt
     2221 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     2281 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     2341 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     2401 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     2461 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     2521 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     2581 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     2641 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     2701 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     2761 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     2821 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     2881 catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca aataagggcg
     2941 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     3001 aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca tgatcagata
     3061 aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag tgaaagagat
     3121 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     3181 gaagaaggcg tcttagagcg ccatgtagga agcggcacct ttgtttccag tactcgagta
     3241 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     3301 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     3361 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     3421 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     3481 gaagaaatca ccagtcattt cttccaaacc ttgcaaaaac atggctatcg tatcggcaaa
     3541 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     3601 gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga tggtactgct
     3661 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     3721 tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt tttctaagaa
     3781 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     3841 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg atattggctc
     3901 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     3961 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     4021 actagtcggg atatcggtct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     4081 gaccattccc acaccaatga ccaagctgct cccccacttt ttaatcaagg ctatgggtaa
     4141 aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac cagcaggtgt
     4201 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     4261 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     4321 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     4381 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     4441 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     4501 agccaagagc atgagaattc caccagcgat taaaagacgc aagttggtca agaccagagc
     4561 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     4621 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     4681 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct ctcgtccttt
     4741 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     4801 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     4861 cgttccttgt catccaaagg agaaaaattt tgacttaagt ctcttgcaaa atcatctgct
     4921 aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc agcgctccca
     4981 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     5041 actgttggaa cagcaagctc aactggccca aacttggttt ccgtcattcc ccaaggtttc
     5101 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     5161 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     5221 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     5281 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     5341 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     5401 caaactgtgc caaccccaac aaccttgctg acactagcta ggtcataaac tagtcctgcc
     5461 tcagtctgca agccatgctc tgggtcactc tggcctaaat agaactctgt ccattgattg
     5521 tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg ttcttctatt
     5581 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     5641 ctttacaaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     5701 ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat aagtcccagg
     5761 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     5821 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     5881 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     5941 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     6001 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     6061 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     6121 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     6181 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     6241 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     6301 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     6361 tttagaattt tttacaagat attatgctca aatttaacat tatttagcta tttagtaaag
     6421 atagtctttc aaggattttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     6481 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     6541 aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc agttctgaat
     6601 tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat tgacaggcaa
     6661 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     6721 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     6781 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaagat tctctagtaa
     6841 cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag tcccaaatag
     6901 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     6961 aacagaaatg tgatttaggt gacgatactt agtttgaatt ttttcttgtt cctttaggag
     7021 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     7081 cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca gctttggctt
     7141 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     7201 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     7261 cctccaagcc ccatgcttta tgaatcccag cttggatgat atcaatgcaa ccatagccac
     7321 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     7381 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     7441 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     7501 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     7561 caaactggtc ctgacacgct cgaaccttga aatgagtcaa agccttgttg acaatggcgt
     7621 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     7681 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     7741 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     7801 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     7861 ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     7921 gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca tctaactggt
     7981 cacgatgact gccatcctct ataaaatctt ccaaaatata agtttggtaa tgatacaagg
     8041 gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta ggatgagctt
     8101 tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc atgagaacac
     8161 cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaattcgt tgattggaaa
     8221 tgaagttccc catttaatag acaatgagct tcttatctcc atctttttca atcgtttcag
     8281 atggttcaac aacgtaaaga tgccctccaa agataatatc cgctccccaa tcgatcatct
     8341 tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca cccatctgag
     8401 gcatgataat ggtgatatct gcttccttct ctgcccgttc aatttcagcc ttcatcttat
     8461 cttcgtttaa atctgaaaga taacgattat agtcttcctg agaaatatac tgctcaattc
     8521 cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact tccttaatga
     8581 ccagcggagc ctgatcacgt ggttcgtgcg tataaactcc gattggagtg attccagctt
     8641 tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa atatgattat
     8701 gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact tcagcaggag
     8761 cattaaagag aggataaccc gctaaataat gatccttatt aatggtttct tcaaaatcac
     8821 caatagctaa atctgcttgc ttgaaccaag gagtcacata ctcaaaattt tcatgaaagt
     8881 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     8941 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagttc
     9001 cctcttgaga aatagtatct cgtttttgac tagtcaagag attccttgga agctttcaaa
     9061 caataagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca caaatccctt
     9121 attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa acgaaaagct
     9181 aaaccaccct gatttcgatt ttgtcttctt tgcatcttca ttctccctac tttcttatgc
     9241 aagccttttc tttttattat atcacagata agtatttctt tcacaattga attgaacttc
     9301 ccatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc attttgtgat
     9361 atcatgtaga ggtaatgaaa ggaaatgaac taatccacag tggcttattc caagtatacc
     9421 acttgggctt tggcagtagt taactgcact aaacataata taaggagaga aaatgtctgc
     9481 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
     9541 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
     9601 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
     9661 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
     9721 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
     9781 cgatttggaa ggcattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
     9841 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
     9901 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
     9961 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
    10021 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
    10081 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
    10141 gatattgtct atggtgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
    10201 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
    10261 gaaaagaagg tgtccatttc ttggacatca aaaaaaaatc tctctgagat gactgaaggt
    10321 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
    10381 atccttgcaa aaacacgcca agaagaaaat tcacttctat tgattctaga tggtctaacc
    10441 gatccccata atctgggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    10501 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    10561 gctattgaac acgttccaat tgcccgagta accaacctca gtcaaacctt agataaactc
    10621 aaggatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    10681 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    10741 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    10801 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    10861 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    10921 taggcttctt gaccagcgat agctccatct ccaactgctg ttgttacttg gcgaaggtct
    10981 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagtcttcat gtggctatct
    11041 gtcacaatcc agcctgcctg atcttggata ttcaattctt taacaaaatc gctaagaggg
    11101 tccaaaccaa catagataaa gacaccaccg aaggcttgct ctgtcacttg acctgttttc
    11161 acattttcaa aaacgacaga ttctactctg ttttcaccct tgattttcct tactacagaa
    11221 tcccatataa agctgatttt ctcattggca aaggcgcgat cttgtaaaac cttttgggca
    11281 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    11341 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    11401 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggc
    11461 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    11521 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    11581 taaatgtgct caacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    11641 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    11701 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    11761 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    11821 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    11881 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    11941 tcataatcat atcatagaga tgggcttggc gagccttggc tgtcttatca actcccgaca
    12001 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    12061 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    12121 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    12181 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    12241 aatctcatcc ggagttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    12301 cgcaacttgg gctacaaagg acatgtcatg actgaccaaa atcatggtct gacctgactt
    12361 agcagcatct gcaatagact tttctacttc accgaccaat tctgggtcaa gggctgaagt
    12421 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    12481 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    12541 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    12601 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    12661 gaaaaccata gacaacttac ggcgtagggc aaggatttct tcttgagtga ttttagaaaa
    12721 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    12781 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    12841 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    12901 attcgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    12961 gcagaaatag ccatttttct ctcgatgaaa cgaccgagac tttcaattcc gatattgact
    13021 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    13081 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    13141 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    13201 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    13261 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    13321 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    13381 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    13441 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    13501 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    13561 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    13621 ccatcaaaga ccgaacgtag gctaaacagc ttgccattcg gaatcaattg catcaagttt
    13681 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    13741 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    13801 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    13861 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    13921 cttaacggtt ccattttcta ctaaaatggg ccgttttaac aacataccgt cacttgctag
    13981 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    14041 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    14101 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    14161 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    14221 aaattctaac atgtgcttct ccttctattg cttctatctt taaaatctac tccttcatgc
    14281 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    14341 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    14401 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    14461 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    14521 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    14581 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    14641 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    14701 agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt
    14761 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    14821 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    14881 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    14941 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    15001 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15061 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15121 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    15181 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    15241 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    15301 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    15361 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    15421 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    15481 cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa
    15541 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    15601 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    15661 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    15721 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    15781 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    15841 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    15901 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    15961 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16021 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16081 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16141 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    16201 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    16261 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    16321 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    16381 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta actgcgtccg
    16441 tacttcaata catcgctatt gtttattaca tgtaaaactc tcagtaggca gagcctgctt
    16501 agagttttac aaacgaattt cccaaagagg aagcaatatg aaagcagtca ttgcttgtgt
    16561 tcataaaatt ctcagaatca tttacaaact actctccacc aagtagactt atcaaaaaga
    16621 aaaggcgcta ggactgaaga aacagttcta acgcccaaat taaaaaaatt tcaactacag
    16681 tatagcacag gaaatgattt tttgcgcttt tttactgttt tttcaaataa aaaaagacaa
    16741 agttttatcc ttgtctttta gttttagtat tgctttggtt tcaatgtcaa taagtgtgtt
    16801 c
//
LOCUS       DAVLBN010000048        16577 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLBN010000048 DAVLBN010000000
VERSION     DAVLBN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.048"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1092
                     /gene="lytB"
                     /locus_tag="VXC24_001574"
     CDS             <1..1092
                     /gene="lytB"
                     /locus_tag="VXC24_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0493667.1"
                     /translation="EWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEK
                     EWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTAN
                     VYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIP
                     YYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTE
                     ATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSK
                     IAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGM
                     NVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1153..2808)
                     /gene="pavA"
                     /locus_tag="VXC24_001575"
     CDS             complement(1153..2808)
                     /gene="pavA"
                     /locus_tag="VXC24_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0493668.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2913..3410
                     /gene="ybeY"
                     /locus_tag="VXC24_001576"
     CDS             2913..3410
                     /gene="ybeY"
                     /locus_tag="VXC24_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0493669.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3391..3786
                     /locus_tag="VXC24_001577"
     CDS             3391..3786
                     /locus_tag="VXC24_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0493670.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3803..4702
                     /gene="era"
                     /locus_tag="VXC24_001578"
     CDS             3803..4702
                     /gene="era"
                     /locus_tag="VXC24_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0493671.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4751..5575
                     /gene="mutM"
                     /locus_tag="VXC24_001579"
     CDS             4751..5575
                     /gene="mutM"
                     /locus_tag="VXC24_001579"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0493672.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5575..6180
                     /locus_tag="VXC24_001580"
     CDS             5575..6180
                     /locus_tag="VXC24_001580"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0493673.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6167..7366
                     /locus_tag="VXC24_001581"
     CDS             6167..7366
                     /locus_tag="VXC24_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0493674.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7366..7515
                     /gene="rpmG"
                     /locus_tag="VXC24_001582"
     CDS             7366..7515
                     /gene="rpmG"
                     /locus_tag="VXC24_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0493675.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7555..7788
                     /gene="secG"
                     /locus_tag="VXC24_001583"
     CDS             7555..7788
                     /gene="secG"
                     /locus_tag="VXC24_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0493676.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7890..10244
                     /gene="rnr"
                     /locus_tag="VXC24_001584"
     CDS             7890..10244
                     /gene="rnr"
                     /locus_tag="VXC24_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0493677.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10207..10674
                     /gene="smpB"
                     /locus_tag="VXC24_001585"
     CDS             10207..10674
                     /gene="smpB"
                     /locus_tag="VXC24_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0493678.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10690..11550
                     /gene="tehB"
                     /locus_tag="VXC24_001586"
     CDS             10690..11550
                     /gene="tehB"
                     /locus_tag="VXC24_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0493679.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11623..12576
                     /gene="coiA"
                     /locus_tag="VXC24_001587"
     CDS             11623..12576
                     /gene="coiA"
                     /locus_tag="VXC24_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0493680.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12595..14397
                     /gene="pepF"
                     /locus_tag="VXC24_001588"
     CDS             12595..14397
                     /gene="pepF"
                     /locus_tag="VXC24_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0493681.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14399..15112
                     /locus_tag="VXC24_001589"
     CDS             14399..15112
                     /locus_tag="VXC24_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0493682.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15179..16120
                     /gene="prsA"
                     /locus_tag="VXC24_001590"
     CDS             15179..16120
                     /gene="prsA"
                     /locus_tag="VXC24_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0493683.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16237..>16577)
                     /locus_tag="VXC24_001591"
     CDS             complement(16237..>16577)
                     /locus_tag="VXC24_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0493684.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLS
                     PVQYRTKSFR"
BASE COUNT         4981 a         3088 c         3720 g         4788 t
ORIGIN      
        1 gaatgggtct acgattctca tagtcaagct tggtactact tcaaatccgg tggttacatg
       61 acagccaatg aatggatttg ggataaggaa tcttggtttt acctcaagtc tgatggcaaa
      121 atggctgaaa aagaatgggt ctacgattct catagtcaag cctggtacta cttcaaatct
      181 ggtggttaca tggcgaaaaa tgagacagta gatggttatc agcttggaag cgatggtaaa
      241 tggcttggag gaaaagctac aaatgaaaat gctgcttact atcaagtagt gcctgttaca
      301 gccaatgttt atgattcaga tggtgaaaag ctttcctata tatcgcaagg tagtgtcgta
      361 tggctagata aggatagaaa aagtgatgac aagcgcttgg ctattactat ttctggtttg
      421 tcaggctata tgaaaacaga agatttacaa gcgctagatg ctagtaagga ctttatccct
      481 tattatgaga gtgatggcca ccgtttttat cactatgtgg ctcagaatgc tagtatccca
      541 gtagcttctc atctttctga tatggaagta ggcaagaaat attattcggc agatggcctg
      601 cattttgatg gttttaagct tgagaatccc ttccttttca aagatttaac agaggctaca
      661 aactacagtg ctgaagaatt ggataaggta tttagtttgc taaacattaa caatagcctt
      721 ttggagaaca agggcgctac ttttaaggaa gccgaagaac attaccatat caatgctctt
      781 tatctccttg cccatagtgc cctagaaagt aactggggaa gaagtaaaat tgccaaagat
      841 aagaataatt tctttggcat tacagcctat gatacgaccc cttacctttc tgctaagaca
      901 tttgatgatg tggataaggg aattttaggt gcaaccaagt ggattaagga aaattatatc
      961 gataggggaa gaactttcct tggaaacaag gcttctggta tgaatgtgga atatgcttca
     1021 gacccttatt ggggcgaaaa aattgctagt gtgatgatga aaatcaatga gaagctaggt
     1081 ggcaaagatt agtactataa gtgaatatga tttgagtgaa tagtaagtta aaaatcctga
     1141 tttcaagtaa aatcaggatt ttttcatgga tgcaattttt ttggagtctg gtgtgacgcg
     1201 gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt ccaccagttg gtttattgag
     1261 ttttttgact tcaatcatat ctacctgcac cagattcgac aggcgccctt gagagaagta
     1321 ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat gggtcaagat ttcctgagat
     1381 gacaacatgg cttccaggaa tgtccttagc atggaaccaa agttcctcct tgcgggccat
     1441 tttaaaggtc aattcctcat tttgaagatt gtttcgtccg acatagatga tggttttgcc
     1501 atcgcttgct agatattgtt ctagtttttt gcgtttctgg attttctccc gttgtcttct
     1561 gcggataaaa cctgtttgaa tcaattcttc acggatttca gcgatttctt ccagtccagc
     1621 ttggttgagg acggtttcta cactttccag atagagaata gtggctttgg tttcttcaat
     1681 caaatcagtc aagtatttga cagcttcttt gagtttctga taccgtttaa aatagcgttg
     1741 ggcattctgg ttgggagtca gagccttatc aagcgcaatc atgataggtt ggttggtata
     1801 gtagttgtct aggataacct ggtcttggtc gttaggcact tggtggagga aggttgtcag
     1861 caattctcct ttttgacgaa attcttcagc gttgtctgtc gccagtaact ctttttcctg
     1921 ttttttgagt ttgtgtcggt ttttctgaag ttcattttca acacgacgaa tcagttcact
     1981 ggcctgctgt ttgacgcggt cgcgctcagc cttatcctta tagtaggtgt ccaacaaatc
     2041 agaaagattt gcaagaggct ctcccacctg atttgcaaaa ggaactggac tgaaggaagt
     2101 ctcagtcaag catggcttgg tttcttgatt gaaaaaattt cggaaagcgg aaagtttttc
     2161 actaaccagt atcctttcca attcatttgc cgtatcgcgt cccagacctt gaaagaggct
     2221 ttgaagattt tttgctgtta gttcttgggt ttgcaggatt tcaaagagct tttcatcctt
     2281 gatagtaaaa ggattgagag attttgtact tggcggagcg atataggtcg atcctggaag
     2341 taaggtgcgg tagctatttt gtgaaaagcc gacgtgtttg ataacttcga ggattttatg
     2401 actgctttta tcgaccagta gaatattact gtgtttcccc ataatttcga taatcaaggt
     2461 agcctggata tggtctccaa tctcgttttt attggaaact gtaatttcca caatacggtc
     2521 attttccact tgctcaatcg actcaatcag ggccccctgc aaatactttc tcaaaaccat
     2581 gataaaggta gaaggttggg ctggattttc aaaagtcgtt tgggtcagct gaatgcgtcc
     2641 aaaaactgga tgggcagaaa ggagcaggcg atggctttgg cgattgctgc ggatttgcaa
     2701 gaccaactct tgttcaaaag gctgattgat tttctggatg cgaccattca ctaattcgct
     2761 tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca aatgacatcg ttctctcctt
     2821 gtgattgtat tccatagtat tatatcaaaa aggtagaata aaatcatgga aatgtggtat
     2881 aataaagcca agtaaagaga aacgagaagc acatgtatat tgaaatggta gatgaaactg
     2941 gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat tttggaattt gcagcccaaa
     3001 aattaggaaa agaagacaag gagatggcag tcacttttgt gaccaatgag cgtagtcatg
     3061 aacttaatct ggggtaccgt gacaccgacc gtccgacaga tgtcatcagc cttgagtata
     3121 aaccagaatt ggaaattgcc tttgacgaag aggatttgct tgaaaatcca gaattggcag
     3181 agatgatgtc tgagtttgat gcctatattg gggaattgtt catctctatc gataaggctc
     3241 atgagcaggc cgaagaatat ggtcacagct ttgagcgtga gatgggcttc ttggcagtac
     3301 acggcttttt acatattaac ggctatgatc actatactcc ggaagaagaa gcggagatgt
     3361 tcggtttaca agaagaaatt ttgacagcct atggactcac aagacaataa acgaaaatgg
     3421 aaaaatcgtg acctgatatc cagtttagaa tttgccatca cagggatttt tactgctatc
     3481 aaggaagaac gcaatatgcg aaaacatgca gtgacggctc tagtggtcat ccttgcaggt
     3541 tttggttttc aggtgtcacg aatcgaatgg ctctttctcc tattgagcat tttcttggtg
     3601 gtagcctttg aaattatcaa ttctgctatc gaaaatgtgg tggatttggc cagtcactat
     3661 cacttttcca tgctggctaa aaatgccaag gatatggcgg ctggcgcggt attagtggtt
     3721 tctctttttg cagccttaac aggcgcattg atttttctcc cacgaatctg ggatttatta
     3781 ttttaaacag taagaggaaa ttatgacttt taaatcaggc tttgtagcca ttttaggacg
     3841 tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg gggcaaaaga ttgccatcat
     3901 gagtgacaag gcgcagacaa cgcgcaataa aatcatggga atttacacga ctgataagga
     3961 gcaaattgtc tttatcgaca caccagggat tcacaaacct aaaacagctc tcggagattt
     4021 catggttgag tctgcctaca gtacccttcg cgaagtggac actgttcttt tcatggtgcc
     4081 tgctgatgaa gcgcgtggta agggggacga tatgattatc gagcgtctca aggctgccaa
     4141 ggttcctgtg attttggtgg tgaataaaat cgataaggtc catccagacc agctcttgtc
     4201 tcagattgat gacttccgta atcaaatgga ctttaaggaa attgttccaa tctcagccct
     4261 tcagggaaat aacgtgtctc gtctagtgga tattttgagt gaaaatctgg atgaaggttt
     4321 tcaatatttc ccgtctgatc aaatcacaga ccatccagaa cgtttcttag tttcagaaat
     4381 ggttcgcgag aaagtcttgc acctaactcg tgaagagatt ccgcattctg tagcagtagt
     4441 tgttgactct atgaaacgag acgaagagac agacaaggtt cacatccgtg caaccatcat
     4501 ggtcgagcgc gatagccaaa aagggattat catcggtaaa ggtggcgcta tgcttaagaa
     4561 aatcggtagc atggcccgtc gtgatatcga actcatgcta ggagacaagg tcttcctaga
     4621 aacctgggtc aaggtcaaga aaaactggcg cgataaaaag ctagatttgg ctgactttgg
     4681 ctataatgaa agagaatact aagtagaggt gggctcatgc ctgcttcttg tttttacaga
     4741 aggaggactt atgcctgaat tacctgaggt tgaaaccgtt tgtcgttgct tagaaaaatt
     4801 gattatagga aagaagattt cgagtataga aattcgctac cccaagatga ttaagacgga
     4861 tttggaagag tttcaaaggg aattgcctag tcagattatc gagtcaatgg gacgtcgtgg
     4921 aaaatatttg cttttttatc tgacagacaa ggttttgatt tcccatttgc ggatggaggg
     4981 caagtatttt tactatccag accaaggacc tgaacgcaag catgcccatg ttttctttca
     5041 ttttgaagat ggtggcacgc ttgtttatga ggatgttcgc aagtttggaa ccatggaact
     5101 cttggtgcct gaccttttag acgcctactt tatttctaaa aaattaggtc ctgaaccaag
     5161 cgaacaagac tttgatttac aggtctttca atctgccctt gccaagtcca aaaagcctat
     5221 caaatcccat ctcctagacc agaccttggt agctggactt ggcaatatct atgtggatga
     5281 ggttctctgg cgagctcagg ttcatccagc tagatcttcc cagactttga cagcagaaga
     5341 agcgacagct attcatgacc aaaccattgc tgttttgagc caggctgttg aaaaaggcgg
     5401 ttccaccatt cggacctata ccaatgcctt tggggaagat ggaagcatgc aggattttca
     5461 tcaggtctat gataagactg gtcaaggatg tgtacgctgt ggtaccatca ttgagaaaat
     5521 tcaactaggt ggacgtggaa cccacttttg tccaaactgt caaaggaggg actgatggga
     5581 aaaatcatcg gaatcactgg gggaattgcc tctggtaagt caactgtgac aaattttcta
     5641 agacagcaag gctttcaagt agtggatgcc gacgcagtcg tccaccaact acagaaacct
     5701 ggtggtcgtc tgtttgaggc tctagtacag cacttttggc aagaaatcat tcttgaaaac
     5761 ggagaactca atcgccctct cctagctagt ctcatctttt caaatcctga tgaacgagaa
     5821 tggtctaagc aaattcaagg ggagattatc cgtgaggaac tggctacttt gagagaacag
     5881 ttggctcaga cagaagagat tttcttcatg gatattcccc tactttttga gcaggactac
     5941 agcgattggt ttgctgagac ttggttggtc tatgtggacc gagatgccca agtagaacgc
     6001 ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt ctcgtctggc agcccagtgg
     6061 cctttagaaa aaaagaaaga tttggccagc caggttcttg ataataatgg caatcagaac
     6121 cagcttctta atcaagtgca tatccttctt gagggaggta ggcaagatga cagagattaa
     6181 ctggaaggat aatctgcgca ttgcctggtt tggtaatttt ctgacaggag ccagtatttc
     6241 tttggttgta ccttttatgc ccatcttcgt ggaaaatcta ggtgtaggga gtgagcaagt
     6301 cgctttttat gcaggcttag caatttctgt ctctgctatt tccgcggcgc tcttttctcc
     6361 tatttggggt attcttgctg acaaatacgg ccgaaaaccc atgatgattc gggcaggtct
     6421 tgctatgact atcactatgg gaggcttggc ctttgtccca aatatctatt ggttaatctt
     6481 tcttcgttta ctaaacggtg tatttgcagg ttttgttcct aatgcaacgg cactgatagc
     6541 cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt actttgtcta caggcgtagt
     6601 tgcaggtact ctaactggtc cctttattgg tggctttatc gcagaattat ttggcattcg
     6661 tacagttttc ttactggttg gtagttttct atttttagct gctattttga ctatttgctt
     6721 tatcaaggaa gattttcaac cagtagccaa ggaaaaggct attccaacaa aggaattatt
     6781 tacctcggtt aaatatccct atcttttgct caatctcttt ttaaccagtt ttgtcatcca
     6841 attttcagct caatcgattg gccctatttt ggctctttat gtacgcgatt tagggcagac
     6901 agagaatctt ctttttgtct ctggtttgat tgtgtccagt atgggctttt ccagcatgat
     6961 gagtgcagga gtcatgggca agctaggtga caaggtgggc aatcatcgtc tcttggttgt
     7021 cgcccagttt tattcagtca tcatctatct cctctgtgcc aatgcctcta gcccccttca
     7081 actaggactc tatcgtttcc tctttggatt gggaaccggt gccttgattc ccggggttaa
     7141 tgccctactc agcaaaatga ctcccaaagc cggcatttcg agggtctttg ccttcaatca
     7201 ggtattcttt tatctgggag gtgttgttgg tcccatggca ggttctgcag tagcaggtca
     7261 atttggctac catgctgtct tttatgcgac gagcctttgt gttgccttta gttgtctctt
     7321 taacctgatt caatttcgaa cattattaaa agtaaaggaa atctagtgcg agtaaaaatt
     7381 aatctcaaat gctcctcttg tggcagtatc aattacctaa ccagtaaaaa ttcaaaaacc
     7441 catccagaca agattgaggt tttaaagtat tgtcccaagg aaagaaaagt aaccctacat
     7501 cttgaatcta agtagatttt atggtaaaat aatagggatt ttaaggagtt tgatatgtat
     7561 aacctattat taaccatttt attagtatta tctgttgtga ttgtgattgc aattttcatg
     7621 caaccaacca aaaaccaatc cagcaatgta tttgatgcca gttcaggtga tttgtttgaa
     7681 cgtagtaaag ttcgcggttt tgaagctgta atgcagcgtt tgacagggat tttagtcttt
     7741 ttctggctag ccattgcctt agcattgacg gtattatcaa gtagataaga aaataatggg
     7801 caggactagg tctttgcctc tttttatttt taaaggatgt ttgagaaggt tttacagtaa
     7861 aagaaaatta aaaaatctag aaagaaaata tgaaagatag aataaaagaa tatttacaag
     7921 acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt gggaaaagac agttccaagg
     7981 attttcgtga gttgattaaa accttgtcct taatggaaag aaagcaccaa attcgttttg
     8041 aagaagatgg tagtctgaca ttagaaatta agaaaaaaca tgagattacc ctcaagggga
     8101 tttttcatgc ccataaaaat ggctttggct ttgttagtct ggaaggcgag gaggacgacc
     8161 tttttgtagg gaaaaatgat gtcaactatg ctattgatgg tgataccgtc gaggtagtga
     8221 ttaagaaagt cgctgaccgc aataagggaa cagcagcaga agccaaaatt attgatatcc
     8281 tagaacacag tttgacaaca gttgtcgggc aaatcgttct ggatcaggaa aaacctaagt
     8341 atgctggcta tattcgttca aaaaatcaga aaatcagtca accgatttat gttaagaaac
     8401 cagccctaaa attagaagga acagaagttc tcaaagtctt tatcgataaa tacccaagca
     8461 agaaacatga tttctttgtc gcgagtgttc tcgatgtagt gggacactca acggatgtcg
     8521 gaattgatgt tcttgaggtc ttggaatcaa tggacattgt atccgagttt ccagaagctg
     8581 ttgttaagga agcagaaagt gtgcctgatg ctccgtctca aaaggatatg gaaggtcgtc
     8641 tggatctaag agatgaaatt acctttacca ttgacggtgc ggatgccaag gacttggacg
     8701 atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga gcttggggtt cacatcgcag
     8761 atgtttctta ttatgtgacc gaggggtctg cccttgacaa ggaagccctt aaccgtgcga
     8821 cttctgttta cgtgacagac cgagtggtgc caatgcttcc agaacgacta tcaaatggca
     8881 tctgctctct caatccccaa gttgaccgcc tgacccagtc tgctattatg gagattgata
     8941 aacatggtcg tgtggtcaac tataccatta cacaaacagt tatcaagacc agttttcgta
     9001 tgacctatag cgatgtcaat gatatcctag ctggcgatga agaaaagaga aaagaatatc
     9061 ataaaattgt atcaagtatc gaactcatgg ccaagcttca tgaaacttta gaaaacatgc
     9121 gtgtgaaacg tggagctctc aattttgata ccaatgaagc gaagatttta gtggataaac
     9181 aaggtaagcc tgttgatatc gttcttcggc agcgtggtat tgccgagcgg atgattgagt
     9241 cttttatgtt gatggctaat gaaacagttg ccgaacattt cagcaagttg gatttgcctt
     9301 ttatctatcg aattcacgag gagcctaagg ctgaaaaggt tcagaagttt attgattatg
     9361 cttcgagttt tggcttgcgc atttatggaa ctgccagtga gattagtcag gaggcacttc
     9421 aagacatcat gcgtgctgtt gagggagaac cttatgcaga tgtattgtcc atgatgcttc
     9481 ttcgctctat gcagcaggct cgttattcgg agcacaatca cggccactat ggactagctg
     9541 ctaactatta tactcacttt accagtccaa ttcgtcgtta tccagacctt cttgttcacc
     9601 gtatgattcg ggattacggc cgttctaagg aaatagcaga gcattttgaa caagtgattc
     9661 cagagattgc gacccagtct tccaaccgtg aacgtcgtgc catagaagct gagcgtgaag
     9721 tcgaagccat gaaaaaggct gagtatatgg aagaatacgt gggtgaagag tatgatgcag
     9781 ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt gccaaacaca gttgaaggct
     9841 tgattcacat cactaatcta cctgaatttt atcatttcaa tgagcgtgat ttgactcttc
     9901 gtggagaaaa atcaggtatc actttccgag tgggtcagca gatccgtatc cgtgttgaaa
     9961 gagcggataa aatgactgga gagattgatt tttcattcgt acctagtgag tttgatgtga
    10021 ttgaaaaagg cttgaaacag tctagtcata gtggcagagg gcgtggttca aatcgtcgtt
    10081 cggataagaa ggaagacaag agaaaatcag gacgctcaaa tgataagcgt aagcattcac
    10141 aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa ggaagtagct aagaaaggag
    10201 ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa ataaaaaggc acgccacgac
    10261 tatacaatcg tagatacgct agaggcaggg atggtcctga ctggaactga aatcaagagt
    10321 gtacgagctg ctcgaattaa tctcaaggat ggctttgctc aagtgaaaaa tggagaagtt
    10381 tggctgagca atgttcatat cgcgccttac gaagagggca atatctggaa ccaggaacca
    10441 gaacgtcgtc gtaaactcct gctccataaa aagcaaattc aaaaattgga acaagagacc
    10501 aaagggacag gaatgacctt agttcccctt aaggtctata taaaagatgg ctacgctaag
    10561 cttcttttag gacttgccaa agggaagcat gactatgaca aacgggagtc tatcaaacgt
    10621 cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg ttaatcagcg ataaaaagag
    10681 gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc ctttgtggaa taaacaaaca
    10741 atgcctgaag ctgttcagca aaagcacaat acaaaagttg ggacttgggg gaaaattact
    10801 gtcttgaagg gagctctcaa gtttattgaa ttgacagaag aaggggaagt tctagctgaa
    10861 cacctctttg aagcaggggc agacaatcca atggcccaac ctcaagcctg gcaccgagtg
    10921 gaagctgcca cagatgatgt ggaatggtac ttggaatttt attgtaaacc tgaggattat
    10981 tttgctaaaa aatacaatac caatcctgtt cattcagagg tcctagaggc catgcagaca
    11041 gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg ggcgtaattc tctttttcta
    11101 gcccagcaag attttgatgt gacggctgta gatcaaaatg gactagctct tgaaatcttg
    11161 caaagcattg tggagcagga agatttggac atgcctgttg gcctttacga tatcaattca
    11221 gctagcattg aacaagaata tgattttatc gtttcaacag ttgttctcat gtttctacaa
    11281 gcggaccgca ttccagctat tattcaaaat atgcaggaga aaaccagtgt tggtggttac
    11341 aaccttatcg tttgtgccat ggacacggag gattatcctt gctcggttaa tttcccattc
    11401 acctttaaag aaggagaact ggcagactat tacaaggatt gggaattggt taagtacaat
    11461 gaaaatccag gccatttgca ccgtcgcgat gagaatggca atcgtattca actacgcttt
    11521 gcgaccttac tagctaagaa aatcaagtaa acacacatga agattaggaa ttttcctgat
    11581 cttttttctt ttttacgaat gatatagaaa aggagggaat tcatgtttgt tgcgagagat
    11641 gctaggggag aattggtaaa tgtgttagag gataaacttg agaagcaagc atacacctgc
    11701 ccagcttgtg gaggccagct ccatttgcgt caaggaccaa gtgtacggac gcattttgcc
    11761 cataaatcct taaaagactg tgattttttc tttgaaaatg aaagtccaga acacctggcc
    11821 aataaggaat ccctctatca ctggttgaaa aaagagacaa aggttcaatt agagtacccg
    11881 ctttcagaac ttaaacagat tgcggatgta tttgtaaatg gcaatctagc tctagaagtt
    11941 cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa gtgagggata tcgtagtcag
    12001 ggttaccaag tactgtggtt gctgggtcaa aaactgtggc tcaaggagcg tttgactcgt
    12061 ctacagcaag gttttcttta tttcagtcaa aacatgggct tttatgtttg ggaattagac
    12121 aaggaaaaac aagttttaag actcaaatac ctgatttacc aggatctccg cggtaaactc
    12181 cattatcaaa tcaaggaatt ttcctatggt caaggtagtt tattggaaat attgcgtctt
    12241 ccctataaga aacaaaaaat atctcatttt acagtttctg aggacaagga catctgtcgc
    12301 tatatccggc aacaacttta ttatcaaaat ctcttttgga tgaaagaaca agcagaagcc
    12361 tatcaaaagg gagaaaatat cctgacttat ggactgaaag aatggtatcc acaaattcga
    12421 ccaatagtgg gcaaattttt ccagattgaa caagacttga ctagctatta tcagcacttt
    12481 tatacctatt accaaaaaaa tcctcaaaat gattggcaaa agctttatcc accagccttt
    12541 tatcagcaat atttcttgaa aaatatggta gaatagaaag gatggaggaa tctaatggta
    12601 ttacaaagaa atgaaataaa tgaaaaagat acatgggatc tatcaacgat ctacccaact
    12661 gaccaggctt gggaagaagt cttaaaagat ttaacagaac aattggagac agtagcccag
    12721 tatgaaggcc atctcttgga tagtgcggat aacctactag aaatcactga attttctctt
    12781 gaaatggaac gccagatgga gaagctttac gtttatgctc atatgaagaa tgaccaggat
    12841 acacgtgaag ctaagtatca agagtactat gccaaggcca tgacattcta cagccagtta
    12901 gaccaagcct tttcattcta tgagcctgaa tttatggaga ttagcgaaaa gcagtatgct
    12961 gactttttag aagctcaacc aaagctgcag gtttatcaac actattttga caagctcttg
    13021 caaggcaagg atcacgttct ctcacaacgt gaagaagaat tattggctgg agctggagaa
    13081 atctttggtt cagcaagtga aaccttcgct atcttggaca atgcggatat tgtgttccct
    13141 tatgtcctag acgatgatgg taaagaagtt cagctatctc atgggattta cacacgtttg
    13201 atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc aagctcttta tgcgacttac
    13261 gaacaattcc aacacaccta tgccaaaacc ttgcaaacca atgttaaggt gcaaaattac
    13321 cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag ccctcgcagc gaattttgtt
    13381 ccagaaagtg tttatgacaa tttggtagca gcagttcgca agcatttgcc actcttacat
    13441 cgctatcttg agcttcgttc aaaaatcttg gggatttcag atctcaagat gtacgatgtc
    13501 tacacaccgc tttcatctgt tgaatacagt tttacctacc aagaagcctt gaaaaaagca
    13561 gaagatgctt tggcagtctt gggtgaggat tacttgagcc gtgttaaacg tgccttcagc
    13621 gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt caggtgccta ctctggtggt
    13681 tcttacgata ccaatgcctt tatgcttctc aactggcagg acaatctgga caatctcttt
    13741 actcttgttc atgaaacagg tcatagtatg cattcaagct atactcgtga aactcagcct
    13801 tatgtttacg gagattactc tatctttttg gctgagattg cctcaactac caatgaaaat
    13861 atcttgacgg agaaattatt ggaagaagtg gaagacgacg caacacgctt tgctattctc
    13921 aataacttcc tagatggttt ccgtggaaca gttttccgcc aaactcaatt tgctgagttt
    13981 gaacacgcca ttcaccaagc agatcaaaat ggggaggtct tgacaagcga tttcctaaat
    14041 aaactctacg cagacttgaa ccaagagtat tatggtttga gtaaggaaga caatcctgaa
    14101 atccaatacg agtgggctcg cattccacac ttctactata actactatgt atatcaatat
    14161 tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa ttgtccatgg tagtcaagaa
    14221 gaccgtgacc gctatatcga ctacctcaag gcaggtaagt cggactatcc acttaatgtc
    14281 atgagaaaag ctggtgttga tatggagaag gaagactacc tcaacgatgc ctttgcagtc
    14341 tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa aattaggatt ggcataaaat
    14401 ggttgaatcg tatagtaaga atgctaacca taacatgcgt cgtcctgtcg tcaaagaaga
    14461 aattgtagac ttgatgcgtc agcgtcaaaa gcaggtcaca ggtttcttga aagaattgga
    14521 aaactttgcc cgcaaggaaa atattcctat tattccccat gaaacggttg cttatttccg
    14581 ttttcttatg gaaaccatgc agcctaaaaa tattctggaa attgggacgg ctatcggttt
    14641 ttcagctctc ttgatggctg aacatgcgcc aaatgctaag attacaacta ttgatcgtaa
    14701 tccagaaatg attggttttg ccaaggaaaa ttttgcccag tttgacagtc gcaagcaaat
    14761 cactctccta gagggagatg cggtggatgt cttatctaca ctgacagagt cttatgattt
    14821 cgtctttatg gattctgcca agtctaaata catcgtcttt ctgccagaaa tcctcaaaca
    14881 tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt caaggtggtg atgttgccaa
    14941 ggatattatg gaagtccgtc gtggtcagcg aaccatttat cgaggccttc aaaaattatt
    15001 tgatgcaacc ttagacaatc cagaactcac cgcaacatta gtgcctttag gagatggtat
    15061 tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct gaaagcgaat gattttcaga
    15121 aaaatttaag aaaaaatagt aaaatagata gagtaacact tatctcaaag gagtagacat
    15181 gaagaaaaaa ttattggcag gtgccatcac actattatca gtagcaactt tagcagcttg
    15241 ttcgaaaggg tcagaagggg cagaccttat cagcatgaaa ggggatgtca tcacagaaca
    15301 tcaattttat gagcaagtga aaaacaaccc ttcagcccaa caagtcttgt taaatatgac
    15361 catccaaaaa gtttttaaaa aacaatatgg ctcagagctt gatgataaag aggttgatga
    15421 tactattgcc gaagaaaaaa aacaatatgg cgaaaactac caacgtgtct tgtcacaagc
    15481 aggtatgact cttgaaacac gtaaagctca aattcgtaca agtaaattag ttgagttggc
    15541 agttaagaag gtagcagaag ctgaattgac agatgaagcc tataagaaag cctttgatga
    15601 gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat aatgaagata aggccaaaga
    15661 agttctcgaa aaagccaagg cagaaggtgc tgattttgct caattagcca aagataattc
    15721 aactgatgaa aaaacaaaag aaaatggtgg agaaattacc tttgattctg cttcaacaga
    15781 agtacctgag caagtcaaaa aagccgcttt cgctttagat gtggatggtg tttctgatgt
    15841 gattacagca actggcacac aagcctacag tagccaatat tacattgtaa aactcactaa
    15901 gaaaacagaa aaatcatcta atattgatga ctacaaagaa aaattaaaaa ctgttatctt
    15961 gactcaaaaa caaaatgatt caacatttgt tcaaagcatt atcggaaaag aattgcaagc
    16021 agccaatatc aaggttaagg accaagcctt ccaaaatatc tttacccaat atatcggtgg
    16081 tggagattca agctcaagca gtagtacatc aaacgaatag tccaaatcaa tgagtcaggg
    16141 aaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa cgcatagtac
    16201 aaggtttgta ctgaccccaa aagttagaca attaatttat ctgaaggatt tagttctgta
    16261 ttgcacaggg ctaagtcctt ttagttttac cttaattctc ttattgttgt aataatcaat
    16321 atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct catagccata
    16381 aaacatttcg gattttaaaa tgccaaagaa agattccatc ctaccgttgt cttggctgtt
    16441 tcctttgcgt gacatagatg cttgaattcc cttactctct aggaagcgat gataagaatc
    16501 gtgttggtat tgccagcctt ggtcactatg gagaatcgta ttctcgtagt gcttctcttt
    16561 gaatgcctgt tccaaca
//
LOCUS       DAVLBN010000049        15012 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLBN010000049 DAVLBN010000000
VERSION     DAVLBN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.049"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     regulatory      39..127
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            342..1010
                     /locus_tag="VXC24_001592"
     CDS             342..1010
                     /locus_tag="VXC24_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0493685.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     gene            complement(1160..1246)
                     /locus_tag="VXC24_001593"
                     /pseudo
     CDS             complement(1160..1246)
                     /locus_tag="VXC24_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            1337..2119
                     /gene="thiM"
                     /locus_tag="VXC24_001594"
     CDS             1337..2119
                     /gene="thiM"
                     /locus_tag="VXC24_001594"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0493686.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            2121..2750
                     /locus_tag="VXC24_001595"
     CDS             2121..2750
                     /locus_tag="VXC24_001595"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0493687.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2959..3047
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3309..3869
                     /locus_tag="VXC24_001596"
     CDS             3309..3869
                     /locus_tag="VXC24_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0493688.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3870..5255
                     /locus_tag="VXC24_001597"
     CDS             3870..5255
                     /locus_tag="VXC24_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493689.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5257..5907
                     /locus_tag="VXC24_001598"
     CDS             5257..5907
                     /locus_tag="VXC24_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0493690.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5918..6610
                     /gene="tenA"
                     /locus_tag="VXC24_001599"
     CDS             5918..6610
                     /gene="tenA"
                     /locus_tag="VXC24_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0493691.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            6615..7139
                     /gene="thiW"
                     /locus_tag="VXC24_001600"
     CDS             6615..7139
                     /gene="thiW"
                     /locus_tag="VXC24_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0493692.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7139..7942
                     /locus_tag="VXC24_001601"
     CDS             7139..7942
                     /locus_tag="VXC24_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0493693.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            7935..8567
                     /locus_tag="VXC24_001602"
     CDS             7935..8567
                     /locus_tag="VXC24_001602"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0493694.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8776..9567)
                     /gene="thiD"
                     /locus_tag="VXC24_001603"
     CDS             complement(8776..9567)
                     /gene="thiD"
                     /locus_tag="VXC24_001603"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0493695.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9651..9749)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9933..10328
                     /locus_tag="VXC24_001604"
     CDS             9933..10328
                     /locus_tag="VXC24_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0493696.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10339..10710
                     /locus_tag="VXC24_001605"
     CDS             10339..10710
                     /locus_tag="VXC24_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0493697.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10720..12963
                     /locus_tag="VXC24_001606"
     CDS             10720..12963
                     /locus_tag="VXC24_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0493698.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13170..14945
                     /gene="spxB"
                     /locus_tag="VXC24_001607"
     CDS             13170..14945
                     /gene="spxB"
                     /locus_tag="VXC24_001607"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0493699.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
BASE COUNT         4414 a         2763 c         3320 g         4515 t
ORIGIN      
        1 ctttcatttt ttgctatact ggttcagtaa ttaaataata gagacatttg gggtgcttta
       61 ggctgagata atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaca
      121 gttttttcgt atggtgaaat gaacggtcta atcttgtaag tcaactctaa ttcttgattg
      181 taattggagt tttttgttta tataaactgg ataggcttgt ttagttagct ctctgcaaat
      241 gctctcgatg tgctttaaaa ggatcaagtg gaattacgat tttgcttgat atttcttggt
      301 gttttattaa ttactaacaa gtaaagagag gagaagtaaa tatggaaaca caagactatg
      361 catttcagcc aggtttgact gttggagaat tattaaaaag cagtcagaag gattggcagg
      421 ctgcaatcaa tcatcgtttt gttaaggaac tttttgcggg gacaattgag aataaggtct
      481 taaaggacta tctgattcaa gattatcact tctttgatgc cttcttatcc atgctgggtg
      541 cctgcgtagc tcacgcagat aaacttgaat ccaagcttcg ttttgccaag caactaggct
      601 ttcttgaagc agatgaagat ggttatttcc aaaaggcttt taaagagtta aaagtagcag
      661 agaatgacta tctagaagtg actttgcacc ctgtaacaaa agcctttcag gatctaatgt
      721 attcggcagt ggcttcatca gactatgccc atcttttggt tatgctggtc attgcagaag
      781 gtctctattt agactggggt tctaaagatt tggctctacc tgaagtctat attcattcgg
      841 aatggatcaa tctccacaga ggtcctttct ttgcagagtg ggttcaattt ctggttgacg
      901 aactcaatcg tgtcggtaaa aatcgagaag atttgacaga acttcagcaa cgctggaatc
      961 aagcagtcgc tttagaatta gctttttttg atattggtta caatgtctag agaaggctca
     1021 tgatatttac aaatttgatg aggtaagact cttcgaaaat ctcttcaaac aacgtcagtt
     1081 tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc tcaaaacagt
     1141 gttttgagct gacttcgtca gtcttatcta caggttcaaa gcagtgtttt gagcaacctg
     1201 cggttagctt cctagtttgc tctttgattt tcattgagta taaatcattc aatgtaaatg
     1261 aaaaaaattt cttaacgaaa gatagatata aatcgaaatc agtagatcgt ataaagtgaa
     1321 aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac cattggtcat
     1381 ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag cactgggcgc
     1441 ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt atgctggtgg
     1501 tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc aagctgctct
     1561 gaaaattgcg gagaaatata atgtcccagc agttttagat cctgtagcct gtggagcagg
     1621 agaatataga aaaaaagtag cggatgatct aatcaacaat tataaactag cagcgattag
     1681 aggaaatgct ggcgagattg cctctttagt aggaatagat gtggcatcta aaggagtaga
     1741 tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga agttcaatat
     1801 tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag tggtaacgat
     1861 tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat taggagctgt
     1921 agtagcaagc tttatcggac tagaaaaagg tcaagaattg aaatcattag aaacagcaat
     1981 gttggtttac aatatcgctg gagaaatagc agaaaaacgt cccaatggac atcttcctgg
     2041 aacatttaaa gctgaattta taaatgcctt atacgagatt acagatgaag atgtaaagga
     2101 attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat tttatttgtg
     2161 gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc ttaaaaggtg
     2221 ctataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc ttagaaaaac
     2281 ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgttcca tttatcgtta
     2341 atgacgatat agatttagca atggaaattg acgccgatgg cgtacatgta ggtcaagatg
     2401 atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt ctttctataa
     2461 gaaacgaaga agaatttcaa caatcaaaag ttgaatatgt agattatgta ggtgttgggc
     2521 ctgtatttga tacccagtca aaagatgatg ctggtggtgc tataggttat gaaggtcttg
     2581 aattgatgag aaaactattg ccacaaatgc ctttagttgc aattggtggg atacagacga
     2641 aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt tcggcaatat
     2701 cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgaacaatag atatctatcc
     2761 ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga ttcagcttga
     2821 atggctaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg ctgtctttgt
     2881 gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt gtgttataat
     2941 aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg atacccattg
     3001 aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg tatgtcgaaa
     3061 agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga gttttttctt
     3121 ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca aatcaattag
     3181 aaaattcaaa ttaatttcta gaaatatttt agcattcctg tgtactgttc taaattcaat
     3241 ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt ttaaaaaagg
     3301 agttttttat gttgaaaaaa tggcagttaa aagatgttat cttgcttgct ttcttgtcta
     3361 tcttttttgg tggggttttc gttggttcag gatatgtgta taatattctc agtctactct
     3421 taacacctct tggtttgcag gcctttgcca atgaaatcct cttcggtctc tggtgtatgg
     3481 ctgcgcccat tgctgccatc tttgttccga gagtcggaag tgcaacgatt ggagaagtgc
     3541 tagctgcgct tgctgaagtc ctttatggta gccaatttgg tctaggagct cttttgtctg
     3601 gcttggttca aggtttggga agtgaatttg gttttatcgt aactaagaat cgctatgaaa
     3661 gttggctctc tctaactgct aatagtattg ggattacgct tgttagcttt gtctatgaat
     3721 acattaagtt aggttactac gccttttccc ttccgtttgt cctttcctta cttgtggtac
     3781 gttttatttc tgtttatttc ttctgtacca tcttggttcg tgccattgtc aaactctatc
     3841 atcagtttgc aactggagga aaagcataga tgggtctgga actacgagcg attcagtccc
     3901 caatcttctc tgagccgttt gattttactt ttcatgcgca agcctttacc ttgttagttg
     3961 ggagcagtgg ttcaggaaaa tccagccttt ttcaagtcat tgcccaagtc agttctcttc
     4021 cctatagtgg tcaagtcctg atagatggga gcgaggtcag tcagctttct atcatcgcac
     4081 gtgtccagaa ggttggcatt ctctttcaaa atcccaatca tcaatttacc atggagaact
     4141 tgtttgagga gctgattttc accttggaga atatcggcta tcaccttcag gaaattgatt
     4201 ctaaaatagc agaggttgtc cagcaatgtc gttgcgaggc aatcttacac cgtcccattc
     4261 atcacctatc aggtggggaa aagcaaaaag cagcgctggc tgtcctcttt gccatgaatc
     4321 ctagggtcta tctcttggat gagcccttcg cttctattga ccgcaagagc agaatcgaga
     4381 tattggagat tctaaaagag ttggctcttg atgggaagac agttattttg tgcgaccatg
     4441 atttatctga ctataaagcc tatatcgacc atatggttga gctaagagac ggaaaactaa
     4501 gggaagtgtt tcaaatccct tcctatgaga tgacacaggt tgcttcaaag gaagttgctt
     4561 ctagcccgga actattccat atgaaccgtg tgactggtga gcttggtaat cgccccctct
     4621 tttcaattgc tgatttcaca ttctatcaag ggatttcctg tatcctgggt gacaatggtg
     4681 tcgggaaatc aaccctcttt cgctctattc ttcaatttca aaagtataag gggcgcattg
     4741 catggaaggg gacagtcctg aaaaagaaaa agagtttgta tcgtgatctg actggtgttg
     4801 ttcaggaagc tgagaagcag tttatccgag tcagtctgcg agaggagctt caattagatg
     4861 gacctgattc tgaaagaaat cagcggattt ttcaagcttt acgatatttt gatttggagc
     4921 aggcagtcga taagagtccc tatcaattaa gtggtggtca gcaaaaaatt cttcagctct
     4981 tgaccatctt gaccagtaag gcttccgtga tcttgctaga tgaacctttt gcaggtttgg
     5041 atgatagagc ctgccattat ttttgcaagt ggattgtgga ggagaggaat caaggaagaa
     5101 gttttctgct cattagtcat cgtttagacc ctttgatttc tgtggttgat tattggattg
     5161 agatgactag tcagggtctt cggcatgtga aagaagtgac cattaccaaa ccacttacat
     5221 ctcagagtag caatacccaa ggggaggtga gatagtatgg tcaaagtagc aacccagaca
     5281 ccgattatca gtctcttctt gctgatttta tccttggaaa catctttcat tccttcgatt
     5341 gctctgaatc tttcggtagt cgcattttgt attctcttta tgctctatta ccgtcgattt
     5401 aaaatgttag cttggatgat catacttgcc attttaccat cttttgccaa ctactgggca
     5461 gttcagttac acggagatgc ttcacaggca gtcatgcttg gaacgagggc ctttgtgaca
     5521 gtttgtatcg gccttgtctt tgtttcctct atttcactaa aagagcttct cttgtacttg
     5581 gctcaaaagg ggctatcacg ctcttggtcc tatgccttga ttgtggtatt caattccttt
     5641 cctctcattc agcaagaaat caagtccctc aaagaagctt gcctattacg tggtcaagaa
     5701 ctgcattttt ggtcgccctt gatttacagt aaggttctga tgacagtctt taggtggcgc
     5761 catctttacc tgagagctct gtctgctcat ggatatgacg aacatgcaca gttgaagaat
     5821 agctatcgga ctttttatat tcctaaaaaa acaaaattaa tctacctgct tttcttttta
     5881 ttgcttcaaa ccagtctatt tttataaagg agttattatg gaatttacag atattgcgat
     5941 ggaattatcc aagaaagctt ggcaggcttc ctttcatcat ccctttattt tacaattaca
     6001 agaggggaat ttagaacctg ccattttccg ctattacctg attcaggatg cctactatct
     6061 gaaggccttc tcagaaatct atcatctttt ggctgataag acttcaaacc aagagatgaa
     6121 aagactcttg aaacaaaatg ctcagggttt agtggagggt gagttattta ttcgccaaca
     6181 atttttcaag gaaatggaaa tcagcgacca ggaaatggag caacatccaa ttgctccaac
     6241 ctgttatcat tacatttctc atatttatag gcaatttgca gaaccgaact tagccatagc
     6301 ttttgcaagc ttgcttcctt gtccttggtt ataccatgat ataggcaaat cacttaatct
     6361 taaaccatca ccaaatcctc tctatcaaca atggattgaa acttatatta cggatgagtt
     6421 agagcaacag atcagagagg agggagcact ggtcaatcag ctctatcgag aaagtgatga
     6481 gacagataag caaaaaatgc tagatgcctt ccacatcagt gttcatatgg aagccaagtt
     6541 ttgggagatg gcttaccaac accagacatg gaagagcgat ttacagtctt tagaaaaagg
     6601 agaagaatag aaacatgaga aagcaccaac tacaagttca caaattgacc attttatcta
     6661 tgatgattgc ccttgatgta gtccttacac ctatctttcg aattgaggga atggcaccga
     6721 tgtccagtgt agtcaatatt ctagcgggaa tcatgatggg acctgtttat gccttggcca
     6781 tggctacagt cacagccttt atccgtatga cgactcaagg gattccgcct ttagctctca
     6841 caggagcgac ttttggagcc cttctggcag gtctctttta taagtacggt cgaaaatttt
     6901 atttttctgc cttgggagaa attgtgggaa caggtattat tggttccatt gtttcctatc
     6961 ctgttatggt actctttaca ggatcagctg ctaagcttag ctggtttatc tacacgcctc
     7021 gatttttcgg agcaaccttg attggtacag cgatttcctt tattgccttt cgatttttaa
     7081 tcaagcagga attctttaaa aaagtgcagg gatatttctt tagtgaaagg atagactgat
     7141 gcaggaattt acaaatccct ttcctatagg ctctagttcc ctaattcact gtatgaccaa
     7201 tgagatttct tgtgagatgc tggcaaatgg gattttggct ctgggatgca aacctgtcat
     7261 ggcagatgat ccccgtgagg ttcttgattt tactaagcaa agtcaggctc ttttcatcaa
     7321 tttggggcat ttgtcagctg agaaggaaaa agcaatccgc atggcagctt cgtatgcaaa
     7381 ccaatcttct ctcccgatgg tagtagatgc ggttggcgta acgacttcat ccattcgtaa
     7441 gagcttagtt aaagaccttt taaactatag acctacggtc attaaaggaa acatgtcaga
     7501 aattcgaagt cttgttggct taaagcacca cggcgttggg gtcgatgcga gtgctaaaga
     7561 tcaagaaacg gaggatttgc ttcaagtctt gaaagactgg tgtcagacct atcctggtat
     7621 gtcattctta gttactggcc ccaaggacct catcgtttcg aaaaatcagg tcgctgtact
     7681 ggagaatggc tgtactgaat tagactggat aacagggaca ggagatttgg ttggagcctt
     7741 aacagccgtt tttctcagcc aaggaaagac tggttttgaa gcttcttgct tagcagtctc
     7801 ttatctcaat atcgctgctg agaaaatagt tgttcaagga atgggattgg aagaatttcg
     7861 ttaccaagta ctcaatcagc tttcgctcct aagaagagat gaaaattggc tagataccat
     7921 caaaggagag gcttatgaat agagaagcac ttagactata tctggtaacc aatcgctatc
     7981 aagattccgt ggaaagcttt cttgcaaaag ttgagacggc ctgccgttca ggggttacca
     8041 tagtccaatt gcgagaaaaa aatctcacaa ccaatcaata ttatcaactg gcaaaacaag
     8101 tcaaggaaat aacagatgcc tatcaggtac ccttgataat cgatgatcgg ttggatgttt
     8161 gtcttgcggt tgatgctgct ggtctgcata ttggagatga cgaactccca gtttcggttg
     8221 cccgacaagt cttgggtcct gaaaaaatcc tcggtgtcac cgctaaaacg gttaaaagag
     8281 ctctggaagc ggagaaatca ggtgcagatt acttggggac aggagccatt tttccgacaa
     8341 ccaccaagga aaatgcaccc atcaccctga tttcaacctt gaaaacaatt tgccaaacgg
     8401 ttgccattcc aatagttgct attggcggct tgacttcgga gaatattgat cagcttatgg
     8461 gcactggcat agctggtgta gctgttgtac gtgatttgat gcaagcagaa gatattgagg
     8521 caaaaacgca agccttttta acaaagttgc atgacattct ttcctaatta atactcaatg
     8581 aaaatcaaag agtaaactag aaagctagtc gcaggttgct caaagtactg ccttgaggtt
     8641 ttagataaga ctgacgaagt cagctcaaaa cagtgttttg aggttgcaga tggaagctga
     8701 cgtagtttga agagattttc gaagggtata aaaactctct aattccctta aagtgggaac
     8761 tagagagttt ttttcttaat ctttaaaagt tgtatggttg actggaccag aaccatgacc
     8821 gagttgaggg gcatcttgaa tagcttttgt gataaaggcc ttggccttat caactgcctg
     8881 gtaaagactc ttgcccttgg ctagttcagc agtaatcact gcagcaaagg tacatccagt
     8941 accatgggtg tgacaggttt gaattcgtgg gctttcccag acaaattgtt cattcttggt
     9001 aaagaggaaa tctttagcac cacctttgag atgtccgcct ttgataacca cagactgagg
     9061 accaaattct tttaaaatca ggcgaccagc acgctgcatg tcttcggggt catggattga
     9121 aaaaccaaca atctcttctg cttcaggaag atttggcgta ataatagttg ctagaggtag
     9181 taagtttgtt ttgagatagt ctctagcatt tgagtcaatc aaggcatctc cacttgtagc
     9241 aaccataaca ggatcaagga catagggaca atccagtttt ttaagatagg gttggatgat
     9301 ttccatgatt tcagtagtag ccaacattcc agtttttaca gcctgaggtg gaatatcaga
     9361 aaagacactc tccaattggg ctttcaacat ttgaggagaa acgtgctcga ttagctgaac
     9421 acctctggta ttttgagcga caagactggt tacaacagcc attccataga catctttcgc
     9481 ttggaatgac tttaaatctg ccataatgcc agcaccacca ctagggtcag tccctgcaat
     9541 ggtcaaagca acgggtaaat aagtcatcta aaacctccca accaactgaa gtttgtattc
     9601 ttaagaacaa gctagtctgt tttagaaagg caatagaaga ctgctagtcc ccattatcat
     9661 ttccacttcc atcagctagc attacctaga ttgagtcaga gggatctaac agtcgttaat
     9721 ctcagcttta cgcaccccta gtggttgttt tcttttttct ttagtatagc atatttttat
     9781 tgtttatata gtaatatttg actgcaaatc gtttttcaaa tgattaaaat tctatttttc
     9841 gaagaaaata ttatttctat aattgacaaa tgtagatttt aagagtatac tgatgagtgt
     9901 aattgacaaa tgtagatttt ggaggtatgg taatgcagat ttcagatgca gaatggcagg
     9961 tcatgaagat tatttggatg cagggggagc agaccagtac agatttgatt agggttttgg
    10021 cagagcggtt tgactggtcc aagtccacgg ttcagacact tttggctcgt ctggttgaga
    10081 aagagtgttt gactcggaaa aaagaaggca agtcctttgt ttattcagcc cttttaactc
    10141 tagaccaaag tcgggattta cttgtccaag atatcaaaga caaggtttgt tcccgtagga
    10201 ttaggaattt gttggctgac ttgattgtag aatgtgaatt tactcagact gacttggaag
    10261 acttggaagc tgtgatttca gagaagaaat caagtgctgt aacagaagta agatgtaatt
    10321 gtatgtaaag gagacgtcat gttaaatagt attgtaacca ttatttgtat tgcccttatc
    10381 gcgtttatct tgttttggtt tttcaaaaag cctgaaaaat ctggacaaaa agcccagcaa
    10441 aaaaacggat accaagagat tcgagtggaa gtcatgggag gctatactcc tgagttgatt
    10501 gtcctcaaga aatcagtgcc agcccgcatt gtctttgacc gcaaggatcc ttcaccatgt
    10561 ctggatcaaa ttgtttttcc agattttggt gtacatacga acctgccaat gggggaagag
    10621 tatgtagtgg aaatcacgcc tgaacaggct ggagaatttg gctttgcttg tggtatgaac
    10681 atgatgcacg gcaagatgat tgtagagtag gtggagacta tgacagaaat tgtgaaagca
    10741 agcttagaaa atggcattca aaaaatccgt atccgatctg aaaaaggcta tcatccagcc
    10801 catatccagc ttcaaaaggg aattccagct gagattacct ttcatcgtgc tactccttca
    10861 aactgttata aggaaattct gtttgaagaa gaaggtatct tggaaccaat cggcgtagat
    10921 gaggagaaag tcattcgttt tacacctcaa gaattagggc gacatgaatt ttcttgtggc
    10981 atgaagatgc aaaagggaag ctatacagtc gttgagaaga ctcgaaaatc tctatctctc
    11041 ctgcaacgtt tttggattac tagtatcttt actgtgcctc ttgtgattct catgattggg
    11101 atgttgacag gtagcattag tcatcaagtc atgcattggg gaacctttct agcaacaacg
    11161 cctattatgt tagttgcagg taagccatat atccagagtg cttgggccag ttttaaaaag
    11221 cacaatgcca acatggatac cttggttgcg ctgggaactc tagtggctta tttctatagc
    11281 ctagttgctc tctttgctgg tctccctgtt tacttcgaaa gtgctggatt tatcctcttt
    11341 ttcgttcttt tgggagcagt ttttgaggaa aaaatgagaa aaaatacgtc ccaagctgtg
    11401 gagaaattac tggacttgca agctaaaacc gcagaagtct tgagtgatga tagttatgtc
    11461 caagttcctt tggaacaagt caaggtaggc gacctgattc gagtgcgtcc cggtgaaaag
    11521 attgctgttg atggtgtcgt agtagaaggt gtctctagta ttgacgaatc catggtgaca
    11581 ggtgagagtc tgcctgtgga caagacagtt ggagatactg tcattggctc aaccatcaat
    11641 catagtggaa cgcttgtctt tagagcagaa aaagttggct cagagactgt tttggctcag
    11701 attgtggatt ttgtgaagaa agctcagaca agtcgtgcgc cgattcagga cttgacggat
    11761 aagatttcag ggatttttgt cccagtagtt gtcattttag gaatcatgac cttttgggtt
    11821 tggttcgtct tgctcaggga tagtgtggtt gtgcttggag ctagctttgt gtcctctctt
    11881 ctctacggag tggcggtttt gattatcgcc tgtccttgtg ccttgggact tgcaacaccg
    11941 acagccctta tggtggggac aggacgtagt gccaagatgg gggttctcct caaaaatgga
    12001 actgtcttac aggaaatcca gaaagttcaa acccttgtct ttgataagac cgggactttg
    12061 acggaaggga aacctgtggt aacagatgtc atcggcgacg aagtagaagt gtttgggttg
    12121 gcagcctcct tggaagatgc ttctcaacac ccactggctg aggctatcgt taagcgagcg
    12181 agtgaagctg gacttgagtt tcaaactgtt gaaaattttc agaccttgca cgggaaaggt
    12241 gtttcagggc gaatcaatgg aaaacaagtt ttacttggaa atgctaaaat gctggatggc
    12301 atggatattt ctaatactta tcaagataaa ctagaagaac tagaaaaaga agctaagaca
    12361 gttgtgttct tagctgttga caatgaaatc aaaggcttgc ttgctttgca agatattcct
    12421 aaggaaaatg ctaagctagc catcagtcag ctaaaaaaac gtggtctccg aacagtcatg
    12481 ctgacaggag acaatgctgg tgtggcgcgt gctattgcag atcaaatcgg aattgaagag
    12541 gtcattgcag gcgtcttgcc agaagaaaaa gcccatgaaa tccataaact gcaacagtca
    12601 gggaaagtag cctttgttgg ggacggtatc aatgacgctc ctgcccttag tgtagcagat
    12661 gtgggaattg ctatgggtgc tggaacagat atcgccatcg agtcagcaga tttggtgttg
    12721 acaaccaata atcttttagg agtggttcgt gcctttgata tgagtaagaa aacctttcat
    12781 cgaattctac tcaatctttt ctgggctttt atctacaatg ttgtcggaat tccgattgca
    12841 gcaggagtct tttcaggtgt tggactggct ctcaacccag aattggcagg tctagccatg
    12901 gcctttagtt ctgtatctgt tctgaccagt tcccttctgt taaattttag taaaatagac
    12961 taaaagtaat gactagattt ctttgttata aaacagaaac gacaacactt tcaaaactgt
    13021 attagaatag agaatagaga gttttgagca gatttttaga aaagtcagca taaatatgat
    13081 acagtggaat agtaaaaatt tggagaacgt ttccaattct atgtaatcgt attctccaag
    13141 tttaaaaaaa ttgaaggaga gttatcatta tgactcaagg gaaaattact gcatctgcag
    13201 caatgcttaa cgtattgaaa acatggggcg tagatacaat ctacggtatc ccatcaggaa
    13261 cactcagctc attgatggat gctttggctg aagacaaaga tatccgtttc ttacaagttc
    13321 gccacgaaga gacaggtgct cttgcagcgg ttatgcaagc taaattcggc ggctcaatcg
    13381 gggttgcagt tggttcaggt ggtccaggtg cgactcactt gattaacggt gtttacgatg
    13441 cagctatgga taacactcca ttcctagcga tccttggatc acgtccagtt aacgaattga
    13501 acatggatgc tttccaagag cttaatcaaa acccaatgta caacggtatc gctgtttaca
    13561 acaaacgtgt agcttacgct gagcaattgc caaaagtaat tgacgaagcc tgccgtgctg
    13621 cagtttctaa aaaaggtcca gctgttgttg aaattccagt aaacttcggt ttccaagaaa
    13681 tcgatgaaaa ctcatactac ggttcaggtt catacgaacg ctcattcatc gctcctgctt
    13741 tgaacgaagt tgaaatcgac aaagctgttg aaatcttgaa caatgctgaa cgcccagtta
    13801 tctatgctgg atttggtggt gttaaagctg gtgaagtgat tactgaattg tcacgtaaaa
    13861 tcaaagcacc aatcatcaca actggtaaaa actttgaagc tttcgaatgg aactatgaag
    13921 gtttgacagg ttctgcttac cgtgttggtt ggaaaccagc caacgaagtg gtctttgaag
    13981 cagacacagt tcttttcctt ggttcaaact tcccattcgc tgaagtttac gaagcattca
    14041 agaacactga aaaatttatc caagtcgata tcgaccctta caaacttggt aaacgtcatg
    14101 ctcttgacgc ttcaatcctt ggtgatgctg gtcaagcagc taaagctatc cttgacaaag
    14161 taaacccagt tgaatcaact ccatggtggc gtgcaaacgt taagaacaac caaaactggc
    14221 gtgattacat gaacaaactc gaaggtaaaa ctgagggtga attgcaattg tatcaagttt
    14281 acaatgcaat caacaaacat gctgatcaag acgctatcta ctcaatcgac gtaggtaaca
    14341 ctactcaaac atctactcgt caccttcaca tgacacctaa gaacatgtgg cgtacatctc
    14401 cactctttgc gacaatgggt attgcccttc ctggtggtat cgctgctaag aaagacaatc
    14461 cagatcgcca agtatggaac atcatgggtg acggagcatt caacatgtgc tacccagacg
    14521 ttatcacaaa cgttcaatac gaccttccag ttatcaacct tgtcttctca aatgctgagt
    14581 acggcttcat caagaacaaa tacgaagata caaacaaaca cttgtttggt gtagacttca
    14641 caaacgctga ctacgctaaa attgcggaag ctcaaggagc tgttggattc acagttgacc
    14701 gtatcgaaga catcgatgca gttgttgcag aagctgttaa attgaacaaa gaaggtaaaa
    14761 ctgttgtcat cgatgctcgc atcactcaac accgtccact tccagtagaa gtacttgaat
    14821 tggatccaaa acttcactca gaagaagcta tcaaagcctt caaggaaaaa tacgaagcag
    14881 aagaactcgt accattccgt ctcttcttgg aagaagaagg attgcaatca cgcgcaatta
    14941 aataattcct ctcgccgaaa atcaaatatg aaacttgtag actttattct ttgattttca
    15001 tagagcagaa ct
//
LOCUS       DAVLBN010000050        14815 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLBN010000050 DAVLBN010000000
VERSION     DAVLBN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.050"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            555..2234
                     /locus_tag="VXC24_001608"
     CDS             555..2234
                     /locus_tag="VXC24_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0493700.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGSNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(2274..4358)
                     /locus_tag="VXC24_001609"
     CDS             complement(2274..4358)
                     /locus_tag="VXC24_001609"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0493701.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQKGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            4529..5809
                     /locus_tag="VXC24_001610"
     CDS             4529..5809
                     /locus_tag="VXC24_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0493702.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            5900..8545
                     /locus_tag="VXC24_001611"
     CDS             5900..8545
                     /locus_tag="VXC24_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0493703.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            8629..9498
                     /locus_tag="VXC24_001612"
     CDS             8629..9498
                     /locus_tag="VXC24_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0493704.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            9492..11372
                     /locus_tag="VXC24_001613"
     CDS             9492..11372
                     /locus_tag="VXC24_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0493705.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            11663..12025
                     /locus_tag="VXC24_001614"
     CDS             11663..12025
                     /locus_tag="VXC24_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493706.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(12077..12926)
                     /locus_tag="VXC24_001615"
                     /pseudo
     CDS             complement(12077..12926)
                     /locus_tag="VXC24_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(12871..13053)
                     /locus_tag="VXC24_001616"
     CDS             complement(12871..13053)
                     /locus_tag="VXC24_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0493707.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            13388..14815
                     /gene="pcpA"
                     /locus_tag="VXC24_001617"
                     /pseudo
     CDS             13388..14815
                     /gene="pcpA"
                     /locus_tag="VXC24_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
BASE COUNT         4342 a         2883 c         3382 g         4208 t
ORIGIN      
        1 aggatataaa atttttttaa aaaatttttc aaaaaatata caaatgacca aaaagtgtcc
       61 aattatcatc tggttatcac ttggatctgt ataaagagaa atgtttgtgt gaaaggataa
      121 aaagatgcaa cattcttttg aagatagatt ttggagaagc atttcttgtt caattgtaca
      181 aattatagaa tcttttctga gtatttagga agagataatt atcttattga ccctcttttt
      241 attttttgtt atagtcgacg aggtgatagt ttagaataat cacttattca caatctgtgg
      301 aaaagtctgg agagtgaatg gtcttcacac aatgacctga aagaagcctg agaataatta
      361 tggagagtag cattctgaga ggtgttagca gaaccatatg acagagctgt ttgaagaggg
      421 aatattgagg agaaaaatcc tgagcctacc agttggagtt ggaaagagct ggctgttaga
      481 tcatggttta ttatccacaa cctgtggata accttgtgaa caagagaagt tgctaaagaa
      541 ggagatatat aacgatgaag aaaatcaaac cgcatggacc gttaccaagt cagactcagc
      601 tagcttatct gggagatgaa ctagcagctt ttatccactt cggttctaat accttttatg
      661 accaagaatg ggggactgga caggaggatc ctgagcgctt taacccgagt cagttggatg
      721 cgcgtgagtg ggttcgtgtg ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca
      781 agcaccacga tggctttgtc ctttatccga cagctcacac agattattcg gttaaggtca
      841 gtccttggag gagaggaaag ggcgacttgc tccttgaagt atcccaagct gccacagagt
      901 ttgatatgga tatgggggtc tacctgtcac cgtgggatgc ccatagtccc ctctatcatg
      961 tggaccgaga agcggactac aatgcctatt atctggctca gttgaaggaa atcttatcaa
     1021 atcctaacta tgggaatgct ggtaagttcg ctgaggtttg gatggatggt gccagaggag
     1081 agggcgcgca aaaggttaat tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc
     1141 agggcgcttg cttgattttt tcaacagaag gcaccagtat ccgctggatt ggcaatgaac
     1201 gagggtatgc aggtgatcca ctgtggcaaa aggtgaatcc tgataaacta ggaacagaag
     1261 cagagctgaa ctatcttcag cacggggatc cctcgggcac gattttttca atcggagagg
     1321 cagatgtttc catccgtcca ggctggttct accatgagga tcaggatcct aagtctctcg
     1381 aggagttggt cgaaatctac tttcactcag tagggcgagg aactccactc ttgcttaata
     1441 ttccgccgaa tcaagctggg ctctttgatg caaaggatat tgaacgactt tatgaatttg
     1501 cgacctatcg caatgagctc tataaagaag atttggctct gggagctgag gtatctggtc
     1561 cagctctttc cgcagacttt gcttgtcgcc atttgacaga cggccttgag accagctctt
     1621 gggcaagcga tgcagacttg cccatccagt tagaactcga cttaggttct cctaaaactt
     1681 ttgatgtaat tgagttaaga gaagatttga agctagggca acgaatcgct gcttttcatg
     1741 tgcaagtaga ggtggatggt gtctggcagg agtttggttc gggtcatact gttggttaca
     1801 aacgtctctt acgaggagca gttgttgaag cacagaagat acgtgtagtc attacagaat
     1861 cacaggcttt gcctttgttg accaagattt cactctataa aactccgagg ttatcacaaa
     1921 cagtagctgt tcaggggcta gcatttgcag aaaaaagcct agctgtggca aagggagaga
     1981 ctcttcattt taggattgaa cgtagtgaaa gtagctcctc tttagaggct aagatttcga
     2041 ttcaaccggg gacaggtgtc catggtgtcg cctatcagga tgagattcaa gtccttcaat
     2101 tccaagcagg ggaaagcaaa aaagatttgc atctaccaac cctgtatttc gcaggagata
     2161 aaaccttgga tttctatctg aacctaacgg tggatggtca gcttgtggat caacttcaag
     2221 tccaagtttc ataaaagaag aacctttgcg cgatgcaaag gttcttttgg ttattagtga
     2281 cttggtaacc agctgagggt gaaagttagt tgttcagctt ttaagaggtc ttggtgttga
     2341 atagttgata cgagtgtttt gtccagtcgg cattctttga caaagttaaa atggttgtgg
     2401 ttttgtttag tatggatatc cagccattta tcttctttag cgaggtagac tcgtagatgg
     2461 tcaaagagag ggattccgag gtcatagctt ggttttcctg gacaggttgg ataaaatccg
     2521 agagctgacc agatgtacca agcagagaga ctaccattgt cttcatctcc aggataggct
     2581 tcccaacttg ggtgaaaagc tttctgacgg agcgtcttga taagaagggc agtgtagtca
     2641 gggtaatcgc tgtagcggaa gagataagga atgtggaaac taggctggtt ggaaatggct
     2701 atttgtccaa aaggagcagt agccatctcg ctcatttcgt gaatttcgta accatagcct
     2761 gttgtttcaa agaggggagc atcttgacag gctttcaaaa gatagttgct aaaggtttct
     2821 tttccaccca tcagttggat taagccaggg atgtcgtgga gaacgcctaa agtagcttga
     2881 atggcagagc attcagcgta gtctcgcccc caactataag gagagaagtc agggtgaaag
     2941 tttccttgat tgtctcgtgc tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa
     3001 ttttgtgaag cagccttgta ggtttcagcg atttctatgt tctctagttt tttggcacag
     3061 ctggcgatac aaaagtcact ataggcatag tctagagtat ggctaacact ttcgtggtgg
     3121 tcggtagaga ggtaacctag ttcttggtat tgggctagtc cgtggcggcc attgattccg
     3181 agagggtcgg ctttgctggc tgtttcgagc atggcttgga agagttctcc ttctaggtca
     3241 ggggccatgt ccttgcaggc gctatctgcg ataataccgt ctaaaagtgt acctggcatc
     3301 ataccccgtt catctggagc cagccatttt ggaaggaaac cagtatcgcg gtagctattg
     3361 aggaaacctt ctaaaaagcg ttgatagtgc tccggtatga taagggcaaa gagggggaag
     3421 gtggtgcgga aggtatccca gaaaccattg ttgctaaaga ggacaccagg cttgacagta
     3481 ccagtagcca gatccatgtg gatggcttgc cctgactcat caacctcata aaaagtctgt
     3541 gggaagagga agagtctgta gaggcagtgg tcaaagaagg ttcggtcagc ctctcctgtc
     3601 tctataatgt caaaacgatg gaggagattt tcccaatccg cttgggcact tgctttacag
     3661 ctatcaaaat cttcttgagg tagattaagc agtgcttgag aaggagagat gaaagaagtg
     3721 gctagttgca tctcggtttg actacttgct aagtcaattc gccagtcccc agcttcttgg
     3781 ctgatagcaa gaatatccgt gttcatttgc agggcagtga acatcgttag cgaatttttg
     3841 ttggtttcag ttttaccttt ttgtcgcagg gcaagagttc gcttatctac ttgctctact
     3901 gtcagttcat ctgttgcgtg aagatagagg gagagggctt tgccttgctt ttgcttcaaa
     3961 cgaatagaag caccgtagca agtcggtgtg agctgggttt caatctgata acgcagagaa
     4021 aagagcttca aatagtgagg ctggaagcaa gctttatcta tatcataaga agactggcgg
     4081 tgaaagaggc tgtctccccc cagttgactg gtgacaggtg tcagaaggag ccaagagtag
     4141 tccccaatcc aaggactggg ctggtgagtt aatcgaatcc cctgaaagat aggcagatgc
     4201 ggatcaaaaa accaagatcc atcctggtca ctggtctggg gcacaaagta attcatccca
     4261 aaaggcacgc ctgtgtatgg cagggtattt ccccaagaga aggcatgctt gctagcagta
     4321 ccaaagcggg tatcgatggt ttcaagtagt ggtttcatag tctttccttt agctgttttt
     4381 ctacattata tcagaaaaag agggacttta gaaaaggagt ttcaaaaata actattttgt
     4441 agaaaaatga ctatcatttg tgtatgtatt ttctgtctca aaagctatat actgaacatg
     4501 aaacttgttt gaaagaggga attgcacgat gatttattcg aaagaaattg ttagagaatg
     4561 gctagatgaa gtagcagagc gggctaagga ccatccagag tgggtggatg ttttcgagcg
     4621 ttgctacacc gataccttgg acaatacggt tgaaatctta gaagatggtt caacttttgt
     4681 cttgactggg gatattcctg ctatgtggct tcgggattcg acagcccagc tcagacccta
     4741 cctgcatgta gctaaaagag atgccctcct gcgtcagacc attgcaggtt tggtcaaacg
     4801 tcagatgacc ttggtactca aggatcctta tgccaattcc ttcaacatag aggaaaactg
     4861 gaaggggcac cacgagaccg accacaccga ccttaatggc tggatttggg aacgcaagta
     4921 tgaggtggac tcgctttgct atcctttgca gttggcttat ctcctctgga aagaaactgg
     4981 cgagactagt cagtttgatg agacttttgt cgcagcgact aaggaaattc tccatctatg
     5041 gacagttgaa caagaccaca agaactctcc ttatcgtttt gtccgagata cggaccgtaa
     5101 ggaagacacc ttggtaaatg atggctttgg acctgacttt gcagtgacag gtatgacttg
     5161 gtcagccttt cgtccgagtg atgactgttg ccagtatagt tacttgattc cgtcaaatat
     5221 gtttgctgta gtagtcttgg gttatgtgca agaaatcttc gcagcattaa acctagctga
     5281 tagccagagt gttattgctg atgccaagcg tcttcaggat gaaatccaag aaggaatcga
     5341 aaactacgct tacaccacca acagtaaggg tgaaaagatt tatgcctttg aagtggatgg
     5401 cctaggaaat gccagcatta tggatgatcc aaacgtacca agtctactag ctgcgcccta
     5461 tctgggctac tgttcggtcg atgatgaagt gtatcaagct actcgccgta ccattctgag
     5521 ctctgaaaat ccatatttct accaaggaga atacgctagc ggtcttggaa gttctcatac
     5581 cttctatcgc tatatctggc caatcgccct ttctatccaa ggcttgacaa caagagataa
     5641 ggcagagaaa aacttcttgc tggatcagct ggttgcctgc gatggcggta caggtcttat
     5701 gcatgaaagc ttccacgtgg atgacccaac tctctactct cgtgaatggt tctcctgggc
     5761 taacatgatg ttctgtgagt tggtcttgga ttacttggat attcgctaag gggctcgctt
     5821 tagctcaacc gattcttatc agaatcacaa gtttacattt aaaacgttaa aatttaaatt
     5881 tagaatgagg ttttacttca tggaaaatgt tgttgtacat attatctcac atagtcactg
     5941 ggaccgtgag tggtacttgc cttttgaaag tcatcgtatg cagttggtgg aattgtttga
     6001 caatctcttt gatctctttg aaaatgaccc tgagttcaag agtttccact tggatggaca
     6061 aactattgtc cttgacgact acttacaaat tcgccctgaa aatcgcgaca aggtccaacg
     6121 ctacattgac gagggcaagc ttaaaattgg tcccttttac atcttgcagg atgattattt
     6181 gatttcaagt gaagccaatg tccgcaatac cttgattggt caacaagaag ctgccaaatg
     6241 gggtaaatca acccagattg gctactttcc agataccttt ggaaatatgg gacaagcacc
     6301 tcaaattctt caaaaatcag gcattcatgt ggcggccttt ggtcgtggtg tgaagccgat
     6361 tggatttgac aaccaagtcc ttgaagatga gcagtttaca tcccagtttt cagaaatgta
     6421 ctggcagggt gtggatggta gtcgtgtttt aggtattctc tttgccaact ggtacagtaa
     6481 tgggaatgaa atcccagttg acaaagatga ggccttgacc ttctggaaac aaaaattgtc
     6541 agatgtgcgt gcctacgctt cgaccaacca atggttgatg atgaacggct gtgaccacca
     6601 gcctgtacag aaaaatctga gcgaagccat tcgtgtggca aatgaactct tcccggatgt
     6661 aatctttgtt catagttctt ttgatgaata tgttcaagct gtagaaggtg cgcttcctga
     6721 acacttatca actgttacag gcgagttgac cagtcaggaa acagatggct ggtacacact
     6781 tgccaacact tcttcatccc gcatttacct gaaacaagcc ttccaagaaa atagcaacct
     6841 cctagagcaa gtggtagaac ccttgactat tatcactggt ggacacaacc acaaggacca
     6901 gttgacctat gcttggaaaa cacttttgca gaacgcgcca catgatagta tctgtggctg
     6961 tagcgtggac gaagttcacc gcgagatgga aacgcgtttt gccaaggtca accaagtagg
     7021 aaactttgtt aaaagtaact tgctcaacga gtggaagggt aaaattgcta cggataaggc
     7081 tcaaagtgac tatctcttta ctgtcattaa cacaggcttg catgataagg tcgatactgt
     7141 cagcacagtg attgatgtgg cgacttgtga tttcaaggaa ttgcacccaa cagaaggcta
     7201 caaaaagatg gctgctctta tcttgccaag ttaccgtgtg gaggacttgg atggtcgtcc
     7261 tgtagaggct acaatcgaag acctcggagc taattttgag tacgatttac caaaagataa
     7321 gttccgccaa gctcgtattg ctcgacaagt gcgcgtgacc attccagttc acctagcgcc
     7381 gctttcttgg acaaccttcc aattgctgga aggaaaacaa gaacaccgtg agggtattta
     7441 ccaaaacgga gtgattgata caccattcgt aacggtgagt gtggatgaca acatcacagt
     7501 ctatgacaag acaactcacg aagcctatga agactttatc cgctttgaag accggggtga
     7561 catcggaaac gagtatatct atttccaacc aaaaggaaca gagccaatct ttgcagagct
     7621 taagggccac gaggtcttgg aaaacacaga tcgctatgct aaaatcttgc tcaaacatga
     7681 attgaccgtg cctgtcagtg cggatgaaaa gctagaagaa gagcaacaag gtatcatcga
     7741 gtttatgaag cgtgaggctg gacggtcaga agaattgaca aacattcctc tggaaactga
     7801 gttgattgtc tttgttgaca atccacaaat ccgcttcaag actcgcttta ctaacactgc
     7861 caaggatcac cgtatccgtc tcttggtcaa gactcataac acgcgtccaa gcaatgattc
     7921 tgaaagtatc tatgaggtgg tgacacgacc aaacaaacca gctgcttcat gggaaaatcc
     7981 tgaaaatcct caacaccaac aagcttttgt cagtctgtat gacgatgaaa aaggggtgac
     8041 tgtatccaac aagggattga atgaatacga aatccttggg gataacacca ttgccgtgac
     8101 cattttgcgt gcatcaggtg agctaggtga ctggggctac ttcccaacgc cagaagcaca
     8161 atgcttgcgt gagtttgaag tcgaatttgc gattgaatgc caccaagccc aagaacgctt
     8221 ctcagcctat cgtcgtgcca aagccttgca gacaccgttt accagccttc agcttgctag
     8281 acaggaagga agcgtggttg cgactggtag cctcttgagc cattctgttc tcagcatacc
     8341 gcaagtttgt ccaacagcct ttaaagtggc ggaaaatgaa gaaggctatg tcctccgtta
     8401 ctataatatg agtcaagaaa atgtgcgcat atcagaacat caacaaacca ttcttgactt
     8461 acttgagcga ccatatccag ttcattcagg actattggct ccacaagaga ttcgtacaga
     8521 attcatcaaa aaagaagaaa tttaatttca aaaagtaaac atcaaaagaa aggaggggcg
     8581 aaaaagtaag aactaactgc tgattcgccc ctttttatgg taaaaacaat gaccattgca
     8641 acgattgata tcggagggac tgggattaag tttgccagtc tgactcctga tgggaaaata
     8701 ctggataaga caagtatttc aacgcctgaa aacttggagg atttactagc gtggctagat
     8761 caacgcttgt cagaacagga ttacagtggg attgctatga gtgttccagg tgcagtcaat
     8821 caagagacag gtgtgattga tggcttcagt gcggtgccct acatccatgg cttttcttgg
     8881 tatgaggcgc ttagctctta tcagctacct gtccatttag aaaatgatgc caactgcgtt
     8941 ggactcagtg aactactagc tcatccagag cttgaaaatg cagcctgtgt cgtgattggg
     9001 acagggattg gcggagccat gattatcaat ggtagacttc atcgaggtcg ccacggtctg
     9061 ggtggagaat ttggctacat gacaaccctt gcccctgctg aaaaacttaa taactggtcg
     9121 caactagcat caactgggaa tatggtacga tacgtgattg aaaaatctgg tcatactgat
     9181 tgggacggtc gcaagattta ccaagaggcc gcagctggta atgctctttg tcaagaagcc
     9241 attgagcgca tgaaccgcaa tttgacgcaa ggcttgctca atatccagta tctcatcgat
     9301 ccagatgtca tcagtctggg tggctctatc agtcaaaatc cagattttat ccaaggtgtt
     9361 aagaaggctg ttgaagactt tgtcgatgcc tacgaagaat acacggtcgc accagttatc
     9421 caggcctgca cctatcacgc agatgccaat ctctacggtg ctcttgtcaa ctggctacag
     9481 gaggaaaagc agtggtaaga tttataggac ttagtcccaa acaaacgcaa gctattgagg
     9541 ttttaaaagg tcacatttct ctaccagatg tggaagtggc tgtcactcag tctgaccaag
     9601 catctatctc tatccagggt gaggaaggtc actatcaatt gacctatcgc aaacctcacc
     9661 aactttatcg tgccttgtcc ttgttggtaa cagttctagc agaagctgat aaagtagaga
     9721 ttgaggaaca agcagcttac gaagatttgg cttacatggt tgactgttct cgaaatgcgg
     9781 tgctgaatgt ggcttctgcc aagcagatga ttgaggtctt ggctctcatg ggctactcaa
     9841 cctttgagct ttacatggaa gacacttacc agattgaagg acagccttac tttggctatt
     9901 tccgtggagc ttattcagca gaggagttgc aggaaatcga agcctatgcc caacagtttg
     9961 acatgacctt tgtaccatgc atccagacct tggcccactt gtcggccttt gtcaaatggg
    10021 gtgtcaagga agtgcaggag ctccgtgatg tagaggacat tcttctcatt ggcgaagaaa
    10081 aggtttatga cctgattgat ggcatgtttg ccacgttgtc taaactgaag actcgcaagg
    10141 tcaatatcgg gatggacgaa gcccacttgg ttggtttggg acgctacctg attttgaacg
    10201 gtgttgtgga tcgtagtctc ctcatgtgcc aacacttgga gcgcgtgctg gatattgctg
    10261 acaaatatgg tttccactgc cagatgtgga gtgatatgtt cttcaaactc atgtcagcgg
    10321 atggccagta cgaccgtgat gtggaaattc cagaggaaac tcgtgtctac ctagaccgtc
    10381 tcaaagaccg tgtgactctg gtttactggg attattatca ggatagcgag gaaaaataca
    10441 accgtaattt ccgcaatcat cacaagatta gccatgacct tgcatttgca gggggagctt
    10501 ggaagtggat tggctttaca cctcacaacc attttagccg tctagtggct atcgaggcta
    10561 ataaagcctg ccgtgccaat cagattaaag aagtcatcgt aacgggttgg ggagacaatg
    10621 ggggtgaaac tgcccagttc tctatcctac caagcttgca aatctgggca gaactcagct
    10681 atcgccatga cctagatagt ttgtctgcgc acttcaagac caatactggt ctaacggttg
    10741 aggattttat gcagattgac cttgccaacc tcttaccaga cctaccaggc aatctcagtg
    10801 gcatcaatcc caaccgatat gtcttttatc aggatgttct ctgtccgata cttgaccgac
    10861 acatgacacc tgaacaggac aaaccgcact tcgctcaggc tgctgagacg cttgctaaca
    10921 ttaaagaaaa agctggaaac tatgcttatc tctttgaaac tcaggcccag ttgaatgcta
    10981 ttttaagtag caaagtagat gtgggacgac gcattcgtca ggcctaccaa gcggatgata
    11041 aagaaagttt acaacaaatc gccagacaag aattaccaga acttagaagc caaattgaag
    11101 acttccatgc cctctttagt caccaatggc tgaaagaaaa caaggtcttt ggtttggata
    11161 cagttgacat ccgtatgggc ggactcttgc aacgcatcaa acgagcagaa agccgtatcg
    11221 aggtttatct ggctggccag cttgaccgca tcgacgagct ggaagttgaa atcctaccat
    11281 ttactgactt ctacgcagac aaggatttcg cagcaactac agctaaccag tggcatacca
    11341 ttgcgacagc ttcgacgatt tatacgactt aatactcttc gaaaatctct tcaaaccacg
    11401 tcagcttcca tctacaacct caaaacagtg ttttgagcag cctgcagcta gcttcctagt
    11461 ttgctctttg attttcattg agtataaaaa caagaacacc ttgcttggcg cagggtgttt
    11521 cgcgtgaaac agaagaatta tctggtttca aatgctacag ttaaaattag taaaacaaga
    11581 aatagaagct gaaaagccag catctgtaga ggcttggatc atttccgtca aatttaaaaa
    11641 aggttgctac cgacatatat agattccaaa aacaaaaacg ttagcggaac tagcagatgt
    11701 gattttatgg agttttgatt ttgcaaatga tcatgctcac gcatttttca tggataatat
    11761 tgagtggagt catgcagatt cttactttct tagctttgtt agtgacgatg ttgaagaacg
    11821 ttacacagaa aatgtctatc tggatagcct aagtgtcaaa caaaaattta agtttatttt
    11881 cgacttcggt gatgaatggc gttttgaatg ccaagtgctg agagaaatcg agacagagga
    11941 cgaagaagct tatctcgtac gttcggttgg aacgtcgcca gaacaatatc cagattatga
    12001 tggttttgac tatgaagaat ggtaaaattg aaatcagtct gtgtaggctt agtatttcaa
    12061 tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca
    12121 ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaaacgttt
    12181 ttactttggc aaagatgttc tcaaccttgc ttctctcctt ggatagcgca tggttatagg
    12241 ctttatcttc agctgttagt ggcttgagtt tgctggattt acgtgaagtt tgtgcttgag
    12301 gacatatctt catgagccct tgataaccac tgtcagccaa gattttacca acttgtctga
    12361 tatttctgca actcattttg aacaacttca tatcatgaca atagttcaca gtgatatcca
    12421 aagaaacaat tctcccttga cttgtgacaa tcgcttgagc cttcatagcg tgaaatttct
    12481 ttttaccaga atgattcgct aattgttttt ttagggcgat tgatttgtac ttccgtcgca
    12541 tcaatcatta ccgtgtcctc agagctgaga ggagttcttg aaatcgtaac accactttga
    12601 acaagagtta cttcaaccca ttggctccga cggattaagt tgctttcgtg gataccaaaa
    12661 tcagccgcaa tttcttcata agtgcggtat tctcacacat attgaagagt ggccataaga
    12721 aggtcttcta ggcttaattt aggttttcgt ccaccttttg cgtgtttaag ttgataagct
    12781 gtttttaata cagctaacat ctctttaaaa gtcgtgcgct gaacaccaac aagacgctta
    12841 aatcgtgtat cagttaattg tttacttgct tcataatttc gcagggagtc tattgactct
    12901 ttggtaggtg tcaatgtttt tttcatctat cccgagaatt attttcccgc catttgtatt
    12961 tgcaaatgct gagtaggttt cccagaaaga ctctggaaga ttgtttttag cttttttgta
    13021 ttctaaatca accccttcaa attttaagtc catatttttc ctttacatct gttttttgtg
    13081 gttctggtat ttgttcaagt tgagtgataa tatagcgaat tgaatttcga gagtttttac
    13141 tcagttaatt tcttttttaa cccactttaa tttctttttt aacacgggtt aaaaaagaaa
    13201 ttaaagtggg ttaattttcc ttgacttaaa atttaaaaat gatatactgt gtttatggag
    13261 agatgataat ttataaaatg tactactcta ttctactaga taatgattga ataaaacttt
    13321 ttataacaac ggctagcaaa gttataattt tatatctatt agaaaataaa tatgtaagga
    13381 aatttaaatg aaaaaaacta caatattatc attaactaca gctgcggtta ttttagcagc
    13441 atatgtccct aatgaaccaa tcctagcaga tactcctagt tcggaagtaa tcaaagagac
    13501 taaagttgga agtattattc aacaaaataa tatcaaatat aaggttctaa ctgtagaagg
    13561 taacatagga actgttcaag tgggtaatgg agttactcct gtagagtttg aagctggtca
    13621 agatggaaaa ccattcacga ttcctacaaa aatcacagta ggtgataaag tatttaccgt
    13681 tactgaagta gctagtcaag cttttagtta ttatccagat gaaacaggta gaattgtcta
    13741 ctatcctagc tctattacta tcccatcaag cataaaaaaa atacaaaaaa aaaggcttcc
    13801 atggaagtaa agctaaaact attatttttg acaaaggcag tcagctggag aaaattgaag
    13861 atagagcttt tgatttttct gaattagaag agattgaatt gcctgcatct ctagaatata
    13921 ttggaacaag tgcattttct tttagtcaaa aattgaaaaa gctaaccttt tcctcaagtt
    13981 caaaattaga attaatatca catgaggctt ttgctaattt atcaaattta gagaaactaa
    14041 cattaccaaa atcggttaaa acattaggaa gtaatctatt tagactcact actagcttaa
    14101 aacatgttga tgttgaagaa ggaaatgaat cgtttgcctc agttgatggt gttttgtttt
    14161 caaaagataa aactcaatta atttattatc caagtcaaaa aaatgacgaa agttataaaa
    14221 cgcctaaaga gacaaaagaa cttgcatcat attcgtttaa taaaaattct tacttgaaaa
    14281 aactcgaatt gaatgaaggt ttagaaaaaa tcggtacttt tgcatttgcg gatgcgatta
    14341 aacttgaaga aattagctta ccaaatagtt tagaaactat tgaacgttta gccttttacg
    14401 gtaatttaga attaaaagaa cttatattac cagataatgt taaaaatttt ggtaaacacg
    14461 ttatgaacgg tttaccaaaa ttaaaaagtt taacaattgg taataatatc aactcattgc
    14521 cgtccttctt cctaagtggc gtcttagatt cattaaagga aattcatatt aagaataaaa
    14581 gtacagagtt ttctgtgaaa aaagatacat ttgcaattcc tgaaactgtt aagttctatg
    14641 taacatcaga acatataaaa gatgttctta aatcaaattt atctactagt aatgatatca
    14701 ttgttgaaaa agtagataat ataaaacaag aaactgatgt agctaaacct aaaaagaatt
    14761 ctaatcgggg agtagttggt tgggttaaag acaaaggttt atggtattac ttaaa
//
LOCUS       DAVLBN010000051        14071 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLBN010000051 DAVLBN010000000
VERSION     DAVLBN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.051"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(87..284)
                     /locus_tag="VXC24_001618"
     CDS             complement(87..284)
                     /locus_tag="VXC24_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0493708.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(359..1135)
                     /locus_tag="VXC24_001619"
     CDS             complement(359..1135)
                     /locus_tag="VXC24_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0493709.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1257..2003
                     /locus_tag="VXC24_001620"
     CDS             1257..2003
                     /locus_tag="VXC24_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0493710.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2016..2996
                     /locus_tag="VXC24_001621"
     CDS             2016..2996
                     /locus_tag="VXC24_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0493711.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3191..3511
                     /locus_tag="VXC24_001622"
     CDS             3191..3511
                     /locus_tag="VXC24_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0493712.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3557..3865
                     /locus_tag="VXC24_001623"
     CDS             3557..3865
                     /locus_tag="VXC24_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0493713.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3882..5180
                     /locus_tag="VXC24_001624"
     CDS             3882..5180
                     /locus_tag="VXC24_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0493714.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            5331..7769
                     /locus_tag="VXC24_001625"
     CDS             5331..7769
                     /locus_tag="VXC24_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0493715.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7788..8456
                     /locus_tag="VXC24_001626"
     CDS             7788..8456
                     /locus_tag="VXC24_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0493716.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            8474..9562
                     /locus_tag="VXC24_001627"
     CDS             8474..9562
                     /locus_tag="VXC24_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0493717.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10044..12545
                     /locus_tag="VXC24_001628"
     CDS             10044..12545
                     /locus_tag="VXC24_001628"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0493718.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12739..13434
                     /locus_tag="VXC24_001629"
     CDS             12739..13434
                     /locus_tag="VXC24_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493719.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13446..13862
                     /locus_tag="VXC24_001630"
     CDS             13446..13862
                     /locus_tag="VXC24_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493720.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
BASE COUNT         4518 a         2190 c         2952 g         4411 t
ORIGIN      
        1 ttaatttgac tttcctgata gagatgttca catcttattt caattcacta tattagagta
       61 aaattctcta caaaaagaag aatagcctat ttgactattc ttccgagtga tttcaatttc
      121 tttggggaaa tatggagata ctttttaaat actttggcaa aatatttata gtctgaaaat
      181 ccaacttggt cagagatagc gcttaaaggg gagttgggag attcagccat cttatctata
      241 gcttgtttca ggcgatattg taagatatat tcatttagag tcatggggaa gtcttctttg
      301 ataaccttat atagatgctt gttatctgca aatagctaga gcatttcaag gaaataaact
      361 agaaataaca attaatatgg tggttcagaa ataccttttg ataatcaata agatcttcag
      421 gatgaagtgc gttgattcca tccatttcat atttccgatt taataaacga tatttgtttt
      481 caccaaattg atgaaaaggg agtagttgaa cttggtcgat atttaatgag ttaaatagag
      541 tagcgaattt ttctgcatcc tctaaactat tgttaaaatt aggaataact gggattctta
      601 aaacgatagt tttattttga gaaaaagcat aatgaatgtt tttaataatc atttgattaa
      661 aaaccccagt cactttttta tgttttatag aattataatg ttttaggtct gtgtagataa
      721 aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca gtagtttcaa
      781 tggcagtgtg tatgtgatgt tctttagctg attttaagat ggctttagca aattcaaact
      841 gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg taaaattctt
      901 tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg actaaggtga
      961 atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat tcaggattag
     1021 aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga atacccgggc
     1081 cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt tccataagag
     1141 ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat tacgaacgaa
     1201 agtttaattt gttgtttttt gctttttatt ttggtagaat aaaacggagg tgtaaaatga
     1261 aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac gttaatacat
     1321 tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat aaattagagt
     1381 caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga gatgacttaa
     1441 atgtacgttt gtcaattaac tatgaaatta agagaaaaat tgttcaggaa gcagtaaaat
     1501 tggtgtcaga taatgaaaca ataatgatag aatctggatc gacctgtgct ttacttgctg
     1561 aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt tttatagcaa
     1621 attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag tttcagaagg
     1681 attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt catgtgcatc
     1741 aagcttttgt tgggacagat ggttacgata aagagatggg ctttacagga aaagatttaa
     1801 tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt gtactaactg
     1861 actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt caagtctatg
     1921 aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa aatgctggga
     1981 taatggttaa ggtagtttcg taagaggtta aatgtatgaa tcaagatagg aataaactgc
     2041 tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa atagcagcaa
     2101 aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg aatgcaggaa
     2161 ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa aattatgtaa
     2221 aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat gataatccaa
     2281 caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat ctaattgatg
     2341 ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta gatttaattc
     2401 acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct agtcacatac
     2461 acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt catggagagt
     2521 gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat ggtattttgc
     2581 aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata gctgtagtcg
     2641 gaattggtga ttttagcaat aaagggaaac atcaatggtt agacatgctt acagaggatg
     2701 actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga ttttttgatt
     2761 caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagccatc tctttggaag
     2821 atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa gtatcttcga
     2881 ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagataaa aatacaattt
     2941 taaaagtttt ggaagaagat ggtgatttga cttttagaga gattctaggt gagtgaaaat
     3001 gatagactga tcagtttatc gttttttctt tttagtcgat tgcacatttg tgcttatata
     3061 aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag ttgtattcta
     3121 tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat agtgaaatga
     3181 ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa ttttatatgc
     3241 tggcgatgcg aaacaacata tttataaagc attagattac ataaaaaatg gtacatgtga
     3301 acggtgtgaa gaagaaatcc agttagctga tgccgcctta ttagaagccc ataatctaca
     3361 aacaaaattc ttggcacaag aagcgtctgg tacaaagaca gaaattacag ctctctttgt
     3421 tcattcacaa gatcatctca tgactagcat gacggagatt aatttaatca aagaaattat
     3481 tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg ttattaacat
     3541 agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt tttctactgg
     3601 tatgcttgta aataatatga aaattgcagc gcaatctagt ggagttgagg cagaaataga
     3661 ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg cactattggg
     3721 tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt gtgatgttcc
     3781 gatagctgtt attccgatga tggactatgg tatgttagat gggaaaaaag tattagattt
     3841 ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatgtcaaag atggatgttc
     3901 agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata gctctaaaag
     3961 atgggatgtt agcaattttg ccattgacag tagttggcag tttgttcttg attatgggac
     4021 aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct aattggacag
     4081 agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt tcttgttttt
     4141 caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct ggagttctat
     4201 ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa ggtgaggcga
     4261 ttggggacgc tattagtaaa gtttggtttg gaggccaagg aattatcggt gctatcatta
     4321 taggtttggt agtaggaagt atttatacct tctttataaa gagaaaaatt gttattaaga
     4381 tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt ccagcatttg
     4441 taattttctt atcttctatg attgtatata ttttagcgaa gtcattgact aatggcggaa
     4501 cattcataga aatgatttat tctgctattc aagttccgtt gcaaggttta actggatctt
     4561 tgtatggtgc tattggaatt gcattcttta tatcattttt gtggtggttt ggtgttcatg
     4621 ggcaatcggt agtaaatgga gtagtgacag ctctgctttt atctaatctt gatgctaata
     4681 aagctatgtt agcctctggt aatctatcat tagaaaatgg tgcacatatt gttactcaac
     4741 aatttttaga ttcattttta attctatcag gttcagggat tacgtttggt cttgtagttg
     4801 ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt gcagcttttc
     4861 cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc atgaatccag
     4921 ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta tatggagcta
     4981 ttgcaacagg tttcatgcaa ccattctcag gggtaacatt gccttggagt acaccagcta
     5041 ttctatcagg atttttggtg ggtggatggc aaggtgttgt gactcagtta ttagtattgg
     5101 cgatgtctac aatggtttac tttccattct ttaagataca agatcgttta gcttgccaaa
     5161 atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca catttgtgct
     5221 aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat aaaaatcggt
     5281 attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtgcttacg atggtaaata
     5341 cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact gaaaggatga
     5401 acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag agagcagttc
     5461 tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa cgtgcatata
     5521 tgctgaaaga aattttggaa aatatgtcta tctatattga agaagaatct atgattgcgg
     5581 gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg ctagaatttg
     5641 ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat attacagaag
     5701 aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat ttacgtgcta
     5761 gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga ttcttcggta
     5821 tggaaggtaa gatgaattct ggagatgctc acttagcagt taactatcag aaacttttgc
     5881 aatttggttt aagaggtttt gaagagcggg ctcgtaaagc gaaggtagct ctagatttaa
     5941 cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc gtaatcgatg
     6001 ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc gaaaatgcaa
     6061 atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga gtcccatatg
     6121 aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa tgtattttac
     6181 aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat atgtatccat
     6241 atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt gaacgtctga
     6301 caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca catacatttt
     6361 cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact cgagataaga
     6421 aggatgctgt taacccatta tcttatttgg tattaaaatc agttgcacaa acccatctac
     6481 cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc atgaatgagt
     6541 gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat gagattatta
     6601 ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac agtgccattg
     6661 gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt atgagttata
     6721 tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg gcttcgggta
     6781 aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct gaattagaaa
     6841 atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt gaaaattcta
     6901 ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg actgatgatt
     6961 gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat atatcaggat
     7021 tgcaagttgg aattgcaaat ttgtcggatt cattagctgc aattaaaaaa ttggtgtttg
     7081 aggaagaacg tataagccca agtcagcttt ggcatgcact ggaaacagat tatgccggag
     7141 aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat ggtaatgatg
     7201 atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat gaaattgcta
     7261 aatatcctaa tacacgttat ggaagaggtc caattggagg aattcgttat tcaggaacat
     7321 cttctatctc agccaacgta gggcagggac gtggaacatt agcaactcca gatggacgca
     7381 acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat caacacggcc
     7441 ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta ggtggggttc
     7501 tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa ttaaaactaa
     7561 ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa tacaatgttg
     7621 tttccagaga gacgctgatt gacgctcaga aacatcctga aaaacacaga gacttaattg
     7681 ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc caagatgaca
     7741 ttataggacg tactgagcat actttgtaaa ataaagaggt tctttttatg gaatttatgc
     7801 ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg ctagctgggg
     7861 taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt gaacgaatca
     7921 aagatgtaag agaattgatt ggctctacac cctctattca tgttcaggtg atttctcaag
     7981 attttgaagg catcttaaag gatgctcata aaattcgaag acaagcagga gatgatatat
     8041 ttatcaaagt acctgttact ccagctggat tacgtgcaat aaaggcgcta aaaaaagagg
     8101 gctaccatat cactgcaaca gctatttata cagttattca gggattatta gctatcgaag
     8161 caggagcgga ttacctagct ccatattata atagaatgga aaatctgaac attgattcaa
     8221 attctgtcat tcgtcaatta gctcttgcta ttgatagaca gaactctcct agtaagattt
     8281 tagctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca ggtgcgcatg
     8341 ctgttacagc aggagcggat gtttttgaat cagctttcgc catgccatct atccaaaagg
     8401 cggttgatga tttttctgac gattggtttg ttattcaaaa tagtcgttcc atttagatag
     8461 agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg gggaaaatgc
     8521 cttgtttgaa aatgccaaat caattttgga tttgggaaat tgccctattc tattatgcga
     8581 tcagttggtt tatgatattg ttggaaaacg atttgaagat tacctacata ggtatggttt
     8641 ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca atcgagttgt
     8701 tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg gaaagacgat
     8761 tgatagcgca aaagctattg cagatttgat tgaaaagcct gttattattg ctccaacaat
     8821 tgcatcgacc gacgcacctg tatctgcttt atctgttatt tatacagatg aaggtgcatt
     8881 tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata caaaagttat
     8941 ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag caacttgggt
     9001 tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac agcaaacatt
     9061 ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg gtttacaggc
     9121 tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaatattg ttgaagctaa
     9181 tactttattg agtggtctag gttttgaaag tggaggatta gctgcggcgc atgcaattca
     9241 taatggtttt actgcattga caggtgacat tcatcattta acacatggtg aaaaagtagc
     9301 ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac ttgataagta
     9361 tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc atttggatca
     9421 agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg gtgagacaat
     9481 tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta tcgctgtaga
     9541 tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg tagtctttta
     9601 ttgatccctg tattgaattc tatagaagat tgaaatagga tgagaacaaa tcgattggga
     9661 aagtaaaatt aatttctata aatgttttag caattgtttc gtactatttc agattcagtc
     9721 tactatatgt tcttcataaa tcaaaaagcg acataggttg tcggcaatca aaaagcgaca
     9781 taggttgtcg gctatttatt gtgaatacat taattagcat tccagtttta tcttcggtct
     9841 aaaataagta ttttgtgcta tacgagataa gcttcttgac ttactccttg atttactgca
     9901 taacaatggg ataaaaagtg ggagatagag caattcatag tcatcaaaat taatgagata
     9961 cagtatacag tttttccttt aaacacattt caaattccct caaaaatggt ataatagtaa
    10021 catcacaaaa ttggagagag accatgagtt tttacaatca taaagaaatt gagcctaagt
    10081 ggcagggcta ctgggcagaa catcatacat ttaagacagg aacagatgca tcaaaaccta
    10141 agttttatgc gcttgatatg ttcccttatc cgtctggagc tggtctgcac gtaggacacc
    10201 cagaaggtta tactgcaacc gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg
    10261 tccttcaccc aatgggttgg gatgcttttg gtttgcctgc agagcaatac gctatggata
    10321 ctggtaatga cccagcagaa tttacagcgg aaaacattgc caacttcaaa cgtcaaatta
    10381 atgcgcttgg attttcttat gactgggatc gtgaagtcaa cacaacagat ccaaactact
    10441 acaagtggac tcaatggatt ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg
    10501 aagtgccagt aaactgggtt gaggaattgg gaactgccat tgccaatgaa gaagtgcttc
    10561 ctgacggaac ttctgagcgt ggaggctatc cagttgtccg caaaccaatg cgccaatgga
    10621 tgctcaaaat cacggcttac gcagagcgct tgctcaatga cttagatgaa ctagattggt
    10681 cagagtctat caaggatatg caacgcaact ggattggtaa atcaactggt gccaatgtaa
    10741 ctttcaaagt aaaaggaaca gacaaggaat ttacagtctt tactactcgt ccggacacac
    10801 ttttcggtgc gactttcact gtcttggctc ctgaacatga attagtagac gctatcacaa
    10861 gttcagagca agcagaagct gtagcagact ataaacacca agccagcctt aagtctgact
    10921 tggctcgtac agaccttgct aaagaaaaaa caggggtttg gactggtgct tatgccatca
    10981 accctgtcaa tggtaaggaa atgccaatct ggattgcaga ctatgtcctt gctagttatg
    11041 gaacaggtgc ggttatggct gtgcctgccc acgaccaacg tgactgggaa tttgccaaac
    11101 aatttgacct tccaatcgtc gaagtacttg aaggtggaaa tgtcgaagaa gctgcctaca
    11161 cagaggatgg cctgcatgtc aattcagact tcctagatgg actcaacaaa gaagacgcta
    11221 ttgccaagat tgtggcttgg ttggaagaaa aaggctgtgg tcaggagaag gttacctacc
    11281 gtctccgcga ctggctcttt agccgtcaac gttactgggg tgagccaatt ccaatcattc
    11341 attgggaaga tggaacttca acagctgttc ctgaaactga attgccgctt gtcttgcctg
    11401 taaccaagga tatccgtcct tcaggtactg gtgaaagtcc actagctaac ttgacagatt
    11461 ggcttgaagt gactcgtgaa gatggtgtca aaggtcgtcg tgaaaccaac actatgccac
    11521 aatgggctgg ttcaagctgg tactacctcc gctatattga tccacacaat actgagaagt
    11581 tggctgatga ggacctcctc aaacaatggt tgccagtaga tatctacgtg ggtggtgcag
    11641 agcatgctgt tcttcacttg ctttacgctc gtttctggca caaattcctc tatgacctcg
    11701 gtgttgttcc gactaaggaa ccattccaaa aactctttaa ccaagggatg attttgggaa
    11761 caagctaccg tgaccaccgt ggtgctcttg tggcaaccga caaggttgaa aaacgtgatg
    11821 gttccttctt ccatgtagaa acaggggaag agttggagca agcgccagcc aagatgtcta
    11881 aatcgctcaa gaacgttgtt aacccagacg atgtggtgga acaatacggt gccgataccc
    11941 ttcgtgttta tgaaatgttt atgggaccac tcgatgcttc gattgcttgg tcagaagaag
    12001 gtttggaagg aagccgtaag ttccttgacc gagtttaccg tttgattaca agtaaagaaa
    12061 tccttgcgga aaacaatggt gctcttgaca aggtttacaa cgaaacagtc aaagctgtta
    12121 ctgagcaaat tgagtctctc aaattcaaca cagctattgc ccaacttatg gtctttgtca
    12181 atgctgctaa caaggaagat aagctttatg ttgactatgc caaaggcttt attcaattga
    12241 ttgcaccatt tgcacctcac ttggcagaag aactctggca aacagtcgca gaaacaggtg
    12301 agtcaatctc ttatgtagct tggccaactt gggacgaaag taaactggtt gaagacgaaa
    12361 tcgaaatcgt tgtccaaatc aaaggtaaag tccgtgccaa actcatggtc gctaaagacc
    12421 tatcacgtga agaattgcaa gaaattgctc tagcggatga aaaagtcaaa gcagaaattg
    12481 acggtaagga aatcgtgaaa gtgattagtg taccaaataa attggttaat attgttgtaa
    12541 aataaccaat ttatttgctg atttccaacc tcaaacagtt tcccaaactg tttgagccaa
    12601 ctaaactcgt taatatcgtt gtgaaataag gtaggaatcc ttcagagtag aatctggagg
    12661 attttttgaa tcttcttatg aaagtatggt atactatggg caactataaa gtttgaaaag
    12721 tgaaaaaagg agaaagctat gccagtaaat gaatatggtc aaatgattgg ggagtcaatg
    12781 gaaggttata caccaggtga actgccttct attgatttct tagaagggcg ttatgctagg
    12841 atagaggctc tttcagtgga aaagcatgcg gaggatttgc tagctgttta tgggcctgat
    12901 acgcctcagg agatgtggac ctaccttttt caggagccag tagcagatat gggggagctg
    12961 gttagccttt tacatcagat gttggctcgt aaggaccgtt tttactatgc aatcatagac
    13021 aaggcgactg gtaaggcttt gggatctttt tctctcatgc gcattgacca gaataaccga
    13081 gtaatagaag tcggagcagt cactttttct ccagagctaa ggggtacacg gataggaact
    13141 gaagctcagt atctcctagc tcgctatgtt tttgaggagc taaactatcg tcgctacgag
    13201 tggaaatgcg atgccttaaa tctgccatcc agacgagctg cggagcgttt gagctttatt
    13261 tatgaaggaa ccttccgtca ggcagtggtt tataagggac gtacgagaga tacggattgg
    13321 ttgtctatga ttgataagga ctggcctcaa gtcaaagatc gtttggaaac atggttgcgt
    13381 cctgaaaatt ttgataaaaa tggacagcag tacaagagct tgagagaact ttaagaggtg
    13441 ttgacatgat tactattaaa aagcaagaaa ttgtcaagct agaggatgtt ttacatctct
    13501 atcaggctgt cggttggaca aattataccc atcaaccaga gatgctggag caggccttat
    13561 ctcattcatt agtaatttat ctggcacttg atggtgatgc tgtggtgggc ttgattcgtt
    13621 tggttggaga tggattctca tcagtattgg ttcaggattt aatcgtttta ccaatctatc
    13681 agcgtcaagg aattggtagt gccttgatga aagaggcttt agaggattac aaagatgcct
    13741 atcaagtcca gctggtgaca gaagagacag aaagaacctt gggcttctat cgttctatgg
    13801 gctttgaaat cttatccacc tataattgta tagggatgac ttggatgaat cgtaaaaaat
    13861 aacaaaactt gttttttctt aagcaaaatt taaggatggt ctagtattat atagtcatta
    13921 aataaagacc tcctaacttt atttaataaa atcctaaact tttttcatca caatctccta
    13981 atgaagccac ccaatcaggt ggcttttttg cgtggtgagg tgctggtgat agaaattttt
    14041 tgcaaaatag taaaatttta gaaaagttaa g
//
LOCUS       DAVLBN010000052        13597 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLBN010000052 DAVLBN010000000
VERSION     DAVLBN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.052"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(117..1253)
                     /gene="lctO"
                     /locus_tag="VXC24_001631"
     CDS             complement(117..1253)
                     /gene="lctO"
                     /locus_tag="VXC24_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0493721.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(1878..3368)
                     /gene="lysS"
                     /locus_tag="VXC24_001632"
     CDS             complement(1878..3368)
                     /gene="lysS"
                     /locus_tag="VXC24_001632"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0493722.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(3496..3642)
                     /locus_tag="VXC24_001633"
     CDS             complement(3496..3642)
                     /locus_tag="VXC24_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0493723.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            3675..4592
                     /locus_tag="VXC24_001634"
     CDS             3675..4592
                     /locus_tag="VXC24_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0493724.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            4593..5351
                     /locus_tag="VXC24_001635"
                     /pseudo
     CDS             4593..5351
                     /locus_tag="VXC24_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            5363..6223
                     /locus_tag="VXC24_001636"
     CDS             5363..6223
                     /locus_tag="VXC24_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0493725.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(6303..6950)
                     /locus_tag="VXC24_001637"
     CDS             complement(6303..6950)
                     /locus_tag="VXC24_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493726.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6947..7645)
                     /locus_tag="VXC24_001638"
     CDS             complement(6947..7645)
                     /locus_tag="VXC24_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493727.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(7655..8407)
                     /locus_tag="VXC24_001639"
     CDS             complement(7655..8407)
                     /locus_tag="VXC24_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493728.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(8407..9171)
                     /locus_tag="VXC24_001640"
     CDS             complement(8407..9171)
                     /locus_tag="VXC24_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493729.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(9267..9672)
                     /locus_tag="VXC24_001641"
                     /pseudo
     CDS             complement(9267..9672)
                     /locus_tag="VXC24_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9852..10484)
                     /locus_tag="VXC24_001642"
     CDS             complement(9852..10484)
                     /locus_tag="VXC24_001642"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0493730.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(10518..11219)
                     /gene="pyrF"
                     /locus_tag="VXC24_001643"
     CDS             complement(10518..11219)
                     /gene="pyrF"
                     /locus_tag="VXC24_001643"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0493731.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            11540..11632
                     /locus_tag="VXC24_001644"
                     /pseudo
     CDS             11540..11632
                     /locus_tag="VXC24_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11954..12667)
                     /locus_tag="VXC24_001645"
     CDS             complement(11954..12667)
                     /locus_tag="VXC24_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493732.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(12660..13493)
                     /locus_tag="VXC24_001646"
     CDS             complement(12660..13493)
                     /locus_tag="VXC24_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493733.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
BASE COUNT         4351 a         2828 c         2342 g         4076 t
ORIGIN      
        1 actgtcctga ttaatttgtc ctattcttat ttcattttat tatagttttc gatagcgatt
       61 tattcttcca atacacgaag aaaaacctcc acattcagtg gaggcaatct gttttatcaa
      121 tacaatttta agtcacgagg gtcaactggg aaggttgggt tgtatggatt gtgacggagc
      181 ttaaagtgtt tgacatcttc aatggtctga gctccagaca attgcataac tgtcttcaat
      241 tccgcattca agtgttcaaa gacttgacgc acaccgacac taccaccgag agccaagcca
      301 taaataacag ggcgaccaat agctaccaag tctgctcctg aagccaaggc tttaaagacg
      361 tgttgaccac gacgaacacc agagtcaaag acaatcggca cacgtctatc aactgcttct
      421 gccacttctt gaagcgagtc aaaggcagct ggtccaccgt cgatttgacg accaccgtgg
      481 ttggttaccc agataccaga agctcctgca gcaagtgaac gttcaacgtc ctcacggcat
      541 tgtggtccct tgacatacac aggaagacca gagtattcag cgataaattc tacatcgcgt
      601 ggagacaagc gttgtttagc tgatttgtaa acaaagtcca ttgatttacc agcaccttct
      661 ggcaggtatt cttcaacaat cggcatgcca actgggaaga caaaaccatt acgcttatcc
      721 acttcacgat tcccccctac agtagcatct gccgtcaaga caatcgcttt ataaccttca
      781 gccttcacac ggtccatgat gtggcggttg ataccgtcat ccttactaaa gtaaaattga
      841 aaccaatgag gtgtcccttg aagggcttca gaaatctctg gaaggtcaac agtagagtaa
      901 gaactggttg tataaagaga accaaactca tgcacaccac gcgcagtcgc cacttccccc
      961 tgttcattcg ctaatttatg ggccgcaaca ggcgccataa tgattggtga agatagtttt
     1021 tcacctgcaa attcaatctc tgtacttgga ttttcaacat cgcaaagtgt atgaggaacg
     1081 atgagtttgt ggttaaaggc gcggatattc tctcttaaag tgaaagtatc ttccgcccca
     1141 ctagcgatat agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca
     1201 taggtattga tgaagtctac atgaccttct gcattgcttg ttttgtatga cataaaatgc
     1261 cctccttgat taagtaagcg tttgcttttt actacacaac tataataact cttttttcaa
     1321 tcattttcaa gagttttgct taaaaaccat cttatttttt catacaatat actagcccta
     1381 ctttccttaa actctaaact ttagtctata ttaagtgaat cgttgagatt ttttgctgcc
     1441 aggcatttga actacttttt tatttgcgga ttctatctac taatactata aaaaaacaag
     1501 tgaataagac accagaacat cctctaatag gacctatgga cttatatcag tcccatatat
     1561 actgtttaag caagatacta tcctagttga cgctaacttc ctatcccact tattaatttt
     1621 ttatttatag tgaatctgaa caaatcaatt gggaaatcca agtcaatttc tagtactttt
     1681 tgaacagttt cagcgtacta tcgtaaaatg aaataaaaca tgcacaaatt gattagggaa
     1741 tttaaaccaa tttctaacag tgtcttagaa atcaaagtgt actatttcaa cttcaatata
     1801 ctacacttca ttttctcctt aaattcagtc tctttttgaa tcaaaaaatc ccctggtaag
     1861 agccagaggg taagaattta tttcattgtt gggaagagca atacatcacg gatagttgtt
     1921 gtatcagtga ggagcatgca gagacggtcg ataccgattc ccaaaccacc tgttggtggc
     1981 ataccgtatt caagagcctc gatgtagtca tagtcgatgc ctgtcgcttc atcatcacca
     2041 agttctttag ctttagcttg ggcttcaaaa cggctaagtt gatcgattgg gtcgttcaac
     2101 tcagtaaagg cattaccgta ctccttagtc atgataaaga gctcgaaacg gtcagtaaag
     2161 cgttggtctt caggattttt cttagcgagt ggagatacag ctactggatg tccatagaca
     2221 aaggttggtt ggattaaagt ttcttcgaca aactcttcaa agaaggcatt gatgatgtga
     2281 ccaacctcag tgtagtgttt ctcaactgga actttcttct cagcagcgat agctttagct
     2341 tcttccaaag tcatgtcttg ccagaaatcg acaccagtaa tttctctgat agcatccacc
     2401 atatgaacac gcttaaatgg tttgttaatc ttgatttcag taccttggta gttgactggg
     2461 ccatcacctt tgactgattt agcagcgtgt tggataatgc cttccgtcaa gtccatgatg
     2521 tcttggaaat ctgcataagc ttggtaaact tcgatagaag taaactcagg gttatgagta
     2581 gcgtccattc cttcgttacg gaagatacgg ccaatttcat agacacgttc cataccaccc
     2641 acgataaggc gttttaagtg aagctcagtc gcgatacgaa gcaccatgtc aatgttttgg
     2701 gcattgtggt gggtgataaa tggacgggca gcagcaccac cggcttcatt atgaagaaca
     2761 ggtgtttcca cttcaaggaa tcctttttgg tcaaggtaac gacggatttc agagatgatt
     2821 tttgaacgag tgacaaagcg ttcaaagctt tcacgattag aaatcaagtc aaggtaacgt
     2881 ttacggtaaa ttgtttcaac gtctgtcaaa ccatggaatt tctcaggaag aggacgaaga
     2941 gccttagaca agtgtgtgat gtgggttgcc ttgatagaga gttctcccat atccgtacgc
     3001 atcacttcac cttcgacacc aaggaagtca ccaaggtctg cttttttgaa gatttcgtag
     3061 ttttcttcac cgacagcatc cttacgaaca tagatctgaa tctggccttc gcggtcttga
     3121 aggtgggcaa aaccaacttt tcctttacca cgtttggtta ccaagcgtcc tgcgatagta
     3181 gctgtttcgt ttttatcgtg taattgttct ttatcgaggt tggcatattt atcttttaat
     3241 tcttgtgaat ttgcagtacg ttcaaaacgt tttccgaaag gatcgattcc ttgttcgcgg
     3301 agcgcagcca ttttttcacg gcgaacgatc tgctggtcat ttagttcttc catatgttct
     3361 gtagacatgg gatcctccta gttttactca aaattgaata cgatgagtca ttttttgcga
     3421 tacccccatt ttatcataaa taagcaagaa attcacggat aatctttaaa aactaaaaag
     3481 aacctgacgc taaaatcact ggaaagaagt gaaagtatct tccgccccac tagcgatata
     3541 gccaaatgct gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat
     3601 gaaatctaca tgaccttctg cattgcttgt tttgtatgac ataaaatgcc ctccttgata
     3661 agtaagcgtt tactttgtat attgcagttt ggggaagttt gggatccttt ctgctcggtt
     3721 taatcgttag tatcatccga cattatcgaa tccctgtttt ggcgcaagta gcgacagcct
     3781 acattgaatt gtcacgtaat acgccccttt tgattcaact cttctttctc tacttcggtc
     3841 ttccccgaat cgggattgtc ctatcttcag aagtctgtgc aacgcttggg cttgtctttt
     3901 taggaggctc cgccatgcag gattcgggaa tccaagtact ctttcaagga aataacctcc
     3961 tgagaatctt acagggattg ggcgttacga ttgggatatc catcctgtct gtcctcttat
     4021 ccatgatgtt cggaacagtc atgggaatca tcatgacctc ccattctaga atcatacgat
     4081 ttttaacacg attgtatctg gaatttatcc gtatcatgcc ccagctggtg ctactcttca
     4141 tcgtttactt tggcttggct cgaaacttta atatcaatat ctcaggtgag acttcagtta
     4201 ttatcgtttt taccctctgg ggaacagctg aaatgggaga cttggtacgt ggagctatca
     4261 cttctctccc taaacatcag tttgaaagtg gacaggcact cggcttgact aatgttcaac
     4321 tttactacca catcatcatc ccacaagtct tgagaagact gctaccgcag gctatcaatc
     4381 ttgtcactcg gatgattaaa accacttcat tagttgtttt gattggggtt gtggaagtga
     4441 ccaaagttgg acaacaaatc atcgatagca atcgcctgac catcccaact acttcatttt
     4501 ggatttatgg aaccattcta atcttatatt tcgcagtttg ctaccctatt tccaaactat
     4561 ccactcactt agaaaaacat tggagaaact aaatgtctga aactatctta gaaatcaagg
     4621 aactaaaaaa atccttcgga gacaatccca tcctccaagg actttctcta gaaatcaaaa
     4681 aaggggaagt tgttgtcatc ctagggccat ctggttgtgg gaaaagtacc ctccttcgtt
     4741 gcctcaacgg cttagaaagt attcaaggtg gagatattct tctggatggt cagtctatcg
     4801 ttgaaaataa aaaagatttt cacctagttc gccaaaagat tggcatggtc ttttaaagtt
     4861 atgaactctt tccccatctg gatgtcttac aaaacctcat cctaggccct atcaaaactc
     4921 aaggatggga caagaaagaa gtaacggaag aagctttgca attactagat cgtgtcggtt
     4981 tgctggataa acaacatagc tttgcccgtc aattatctgg tggacagaag caacgtgttg
     5041 caattgtccg tgccctccta atgcatccag aaatcatcct ttttgacgag gtgactgctt
     5101 cgctggatcc agaaatggtg cgtgaggtgc tggaacttat caatgatttg gcccaagaag
     5161 gccgtaccat gattttagta acccacgaaa tgcagtttgc ccaagccatt gctgaccgga
     5221 ttatcttcct cgaccaaggg aaaatcgctg aagaaggaac agctcaagcc ttctttacca
     5281 atccgcaaac caaacgagcc caggaatttt taaacgtctt tgactttagc caattcggct
     5341 catatctata aaggagattc ttatgaaact attcaaacca ctcttaactg ttttagcact
     5401 tgcctttgcc cttatcttta tcactgcttg tagctcaggt ggaaacgctg gttcatcctc
     5461 tggaaaaaca actgccaaag ctcgcactat cgatgaaatc aaaaaaagcg gtgaactgcg
     5521 aatcgccgtg tttggagata aaaaaccgtt tggctacgtt gacaatgatg gttcttacca
     5581 aggctacgat attgaactag ggaaccaact agctcaagac cttggtgtca aggttaaata
     5641 catttcagtc gatgctgcca accgtgcgga atacttgatt tcaaacaagg tagatattac
     5701 tcttgctaac tttacagtaa ctgacgaacg taagaaacaa gttgattttg cccttccata
     5761 tatgaaagtt tctctgggtg tcgtatcacc taagactggt ctcattacag acgtcaaaca
     5821 acttgaaggt aaaaccttaa ttgtcacaaa aggaacgact gctgagactt attttgaaaa
     5881 gaatcatcca gaaatcaaac tccaaaaata cgaccaatac agtgactctt accaagctct
     5941 tcttgacgga cgtggagatg ccttttcaac tgacaatacg gaagttctag cttgggcgct
     6001 tgaaaataaa ggatttgaag taggaattac ttccctcggt gatcccgata ccattgcggc
     6061 agcagttcaa aaaggcaacc aagaattgct agacttcatc aataaagata ttgaaaaatt
     6121 aggcaaggaa aacttcttcc acaaggccta tgaaaaaaca cttcacccaa cctacggtga
     6181 cgctgctaaa gcagatgacc tggttgttga aggtggccat taactcttaa aagggactgg
     6241 attttaagct ccaatccctt tttaagattt tacctataac atcctgagtc tatctaagat
     6301 gttcaatctg aacacagtgt acatacttta tcttctattg catatacttt atcacataag
     6361 atacgaatat cctcttcact atgactagca atcaaaattg ttgtcccttt ttcactagag
     6421 agctttctaa acaatgttct catattttct acacttgatt tatccaaggc attcataggt
     6481 tcatctagta aaagaataga gggattctcc ataattgctt gagcaatccc tagctttttc
     6541 ctcataccta gcgaataagt tttaactttc tggtcttttt gctcatatag accaactatt
     6601 ttcagtgtat cattgatttc ctgattacca actactcctc gtatgcttgc caaatattgt
     6661 aaattcttaa agccactata ataatttata aaaccaggtt cttcaatcaa agctcccaaa
     6721 ttagctggaa tttttctctc aggaacaata ttttccccat tgattaacac ttctccataa
     6781 gacggactat ataaaccagc tattaattta aacaatacac ttttccctga gccattcgca
     6841 ccagtgattc ctatgatttc ccctggttta caactaaagt taaggttttg aaaaacacat
     6901 gtctttttta atttcaactc aatatttttt aatatgatta tttcattcat tctataaacc
     6961 tcctcttttg acgagtgaaa tagaaaatac ttttaaaaag aaagactaaa aatagcaact
     7021 gaagaaataa atctcgtcct atatctccat tccctcgatt caaaatataa aatagataat
     7081 tagttcgatt ccctacaaat agaccaccaa acacaatcat gagtaaaaag aaactaacgc
     7141 aagcaaagtt catttgtaca ttcgctccta gtgcgtataa cataaagcaa agcaaggata
     7201 gcacacaagc attcaaagaa tcaactataa acaaaactcc tatatcccag tttggtaact
     7261 gtaacataaa ttgaatcact agaactttta ccatgattaa aatgagtcca taaagaaaac
     7321 aggtccaaat ctgataccta atccagagct taatagaaga aaatcgaatc acttccataa
     7381 agaaatcgga tgctcttcta cgatatacaa ctgctagaaa aaatgtatga ataataaacc
     7441 aatgaagcaa ccatatggat aagactaaaa aagagttttg actcagatta ggccctttta
     7501 aaatttctat aacaagtcta tcatttcctt ctaaccaata ccataatcct aaacaaatca
     7561 atatccaaaa aagaacataa ccccaaaagt acttggtata gattatctga ttcaacctcc
     7621 acatgtaact acttaacttt cccatttcca acttttacac tctcctccag tttctatgaa
     7681 cagaaaatac agtcaatgga attatgatag atagtaatgt aagccaataa atcaatgcat
     7741 acggattgga atttaccata tactgaaaaa ttggcaataa tccaattatc ccattgtcca
     7801 actgataaat ccagaataag gattctacaa ataaaaaagt aaacagaaat actaagctca
     7861 tgtttgattt tttaaaccaa gaaaaactgc taatagtaag taaggataaa aagaaatagt
     7921 atgctatata agagaaaaaa aatcctataa agaaactagc attgtttgca atacttatac
     7981 cataaaattc tcttaaaaaa tcaacctcct ttatctccaa agagaagcta aaaccattac
     8041 taaatgcaat tagaaaaatc aataaaaata aagtcgccgt ccaaatcccc gtactaagag
     8101 ctgctaattt gaaactaaaa ctggtaaagt gcttaattga tttcagacga atgcgacact
     8161 ccaacctatt aaaatagtta ttcatcaaat aaaaaaagaa caatatatat gtgaacggaa
     8221 agcaatatac tccagtcgtc atatcttgaa gtaaaactaa gatccattct aatacatttg
     8281 gatggattga atattggcga cagcgcaata aatatactgt actagataaa acacaggata
     8341 gcagtaatat aaaataaacc aatactgcta agaaatcttt tttataaaat tgaacaaatt
     8401 gtttcattat acgtagtcct ctgaatgtag aaaaaatgta ccataaacaa ccaaacaact
     8461 aacaaataaa ataaaagcaa gatgcccact aactaaggaa agactgatat ctttctgata
     8521 tcccaaagct aatgttgtca caggttctaa gtaagatagc cctaaaatag cccaaaaaat
     8581 accaccaacc atcatatagg caactgggat gaaaatagct cctatttttt tcttcactag
     8641 caaagcacta gctagtccaa aaatagagaa cacagcgccc caaactccat accagagagt
     8701 cgtcacaaga ctatagagca actgattaga atcaaataat tcttttaagg caccactata
     8761 atctccaata taaatttcct gataaggagt cactaaaaga ttaattccta ataataataa
     8821 ataggggaga aaaaagacta gaaaagaaga aataattgca gtactaccca caatagctag
     8881 atacctcttt ttagaaattc ggcacaattg tgctgttaga aaatgactct cagcatcctc
     8941 tattatctga ctagaatagg gcagtgtaca gataagtgca gctactaggc taatcggtga
     9001 aaatcctcga atagaagaag cggcaaaaaa aatcgataaa ccttcaattt tataaatacc
     9061 attgaaagca aggaaatttc ctaaactcat gcaaagaagg gtcaaaaata aagacatata
     9121 aaatcgaggt gattgaacga ctcgtacaag attacaaatg aaaaattcca tccttactcc
     9181 tccttataat aaaaataggg tgtagcattc ttttttcatg ctacacccac aatcaaccat
     9241 ctttaaggct tactctgaca agtaagttaa taagaatctg gactccaaga acctgaagta
     9301 tgaattctta catgatttcc aaattgtggc gccatagcta atctagtacc agaaccaata
     9361 taattgtcac cacctccatt atagtacatg acaatcctag agccagaccc caatgaatat
     9421 accggggtaa tatctgaccc actataggcg cgctacgaat agaggtattt aaccttttac
     9481 cgccaccagt gctgtcacta ttattaattc cagcagaggc gttttctttc tcaagctcac
     9541 tagttgtatc cgaaccccaa cgcggcaacg ttaaatcata atttccaatc tgtctagcta
     9601 aaactgtagg gagaaacaaa ctagatgcaa ttgtaactac gcaaaaaagg aatatatttt
     9661 tcttcttttc atgacatcgt cctcttaaga agtgataaac aagatagttg attgatcaat
     9721 ttgatacata ttacattttc attatatcaa taaaagaaag cgttgtcaat tattttattt
     9781 aaaatattgt catattttaa ataaaatggt aaaagaggct cggtagcctc gtctctcttt
     9841 atcttactga cctaaccttc ttgccaattt tcttggtcgt ctttaaagcg ttttagaaga
     9901 tcaaggccct ctggcgtgat gtaaccttct tcttgggcta gatggataag ctcgctatag
     9961 tttgaaagcg tcacaagttt aacaccagca tctgcaaagt tcttatctgc ttttggcaat
    10021 tggtagctga aaatcgctac aactccaagc acatctgctc cttctcgctt ggctgctgct
    10081 acagcttcaa gaactgaacc acccgttgaa ataaggtctt caaccactac cattttttga
    10141 ccttgagcta cgcgaccttc gatttgatta ccagctccat ggtcttttgg tttgctacgg
    10201 atgtaggcaa aaggcaagtc catcttatca gcaataatgg ctccgtgtgg aatccctgct
    10261 gttgcagttc ctgcaatcac ttctacttca ggaaaggctt ctttgatagc ttccacaaaa
    10321 ccattttcaa ttagggtacg agtttctgga taggctagtg tcacacgatt atcagtgtaa
    10381 atcggtgact tgataccaga tgcccaagtg aagggttcct ctggtttgag gtaaacggct
    10441 tggattttca agaggtggct agcgatatct ttagcaagtg tcatggtatt ctccttttat
    10501 ttttctaatc tagttcttta attccagtcc tgtgtccatt catccttgat ggcatgataa
    10561 gctgcaacag gatcctcagc ttgggtaatg ggacgtccca ctacgatata gtcactgccg
    10621 atttgatagg catcagcagg tgtcatgact cgtttttgat ctccaactgc aacaccagct
    10681 ggacgaatcc ctggtgtcag acagataaaa tctggattgg tagcctgctt gatgacttgt
    10741 acttcctgag ccgagcaaac aacaccatcc aagccagctt cagctgtctt cttggcatag
    10801 tgaatcacag actcttgcag actggtttgg atattttgaa actcctgcat ctgagcttct
    10861 gacgttgatg tgagctgagt tacagcgatc aatttggctt gacttccaag accttcacgc
    10921 gcagccttca tcatctctac accaccagcc gcatgaacat tggtcatatc cacaccaagc
    10981 tgagatagga tcttcattgc tgacttgact gtattaggaa tgtcatgaag tttgagatcc
    11041 aaaaagacac tatgacccaa accttttaag taggacacaa tctcaggccc cgctgcgtaa
    11101 taaagctcca tccctacctt gagataaagg ctttcttctg ctgggaaaag agctaaaaat
    11161 tccttgaccg cctcaaaact aggaaaatca agagcaatga ttggacgatg ttctcgcata
    11221 ggtttctcct tttaccttta ctagtgagag agtctggcca acagaagcca cgaaaaaagg
    11281 aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc accgtctaac
    11341 cttagctgcc tctctggact gctttaaagg ttttttacta ttctattatt tctactagca
    11401 cttgtcaagt aaaaacatgg tcacgtatgt gttgactgct attgaacacc tcacaagact
    11461 ctttccaaaa gaatagttaa agactttcac ttaggacaga gaaaaagagt ttgcttgtta
    11521 ccctttaatt gaacaaatgg gaattctgtt ttattttgcg gatgcctatt catcttggca
    11581 aaggggaagt aatgagaatg cgaatggact tcttcgtgag tattttctta aaccgatttg
    11641 gcaacaatta ccgaaaaaat ccttaatggt gctttgctag cttattaatc accgtcccca
    11701 aaaatacttg gattacaaga caggttttga agcacttata gaggagattt aaaaatgttg
    11761 cattttttat tgcaatttat cagttatctt atcacccaaa acttctgcaa ttagtatgag
    11821 cactattgtt atttttcttt tttcgtacac tcaaatcaaa atatagcaat aagactattc
    11881 tgtagaattg ctgtcaaaaa gatcagttca tttttccttc ccacttgtgt ttataatcat
    11941 taaaataact caattaagaa attttctttt tcctaatagt tatcgtaatt aaagttaata
    12001 gaagaacaat ccaaataagt agtgttagat taggaattag agtttcattc catgaaaatc
    12061 cctcccattt tgtgaaaaac ttagtaaaca gtcccataaa actataatct gttatcttcg
    12121 caactgtctt atccaaacca gatagcatcg gtaagaaagc aactaaaatc atagcaggaa
    12181 gactgataac ctgagctact acttggctct tcgcggttaa acctatcaat aaatagaata
    12241 aaatgatgga taaagaggtt agaagaacga ttgtaatata attaaaagta tgtacaattg
    12301 taactcctaa aataagagga gtagttccca taatcacaaa agttagcaaa aaaggaagaa
    12361 acatcgttga taaaatgtat tcggatcctt taacaccact caacagaaga gtttgtaaat
    12421 tgtacttttc tttttcttca gacaagataa tagttatagg acttccaaca gccaaagcca
    12481 aagaaaaagg taaacacatc atcaaaagaa ctaatgcctg ttgatcgttg accttcccct
    12541 gtgtttccat aagatattta taaaaatatg tgaaagcaaa aggcactaaa acttgcaata
    12601 aaatactctt attggaaagg ataatttgac aacgcaacca taccaaagcc agaaaccgtt
    12661 taagcattta gctttcctcc tgttaatgtg ataaaaatat cttctaaagt aggctcacat
    12721 gaatgaattg aaaaaatatt ttccagatca gcctgagata cctgttctag tgatgtaaaa
    12781 tcaaaagtta tctgattccc attataatct gtaaccttaa tctttttatc tttattatat
    12841 ctttgaatga gttcagaagg agctccttgc tcaactaatt tccctttatt taataaggca
    12901 acataatcac ataaaagagt tgcttcattc atatcatgag tcgttagaaa aatcgttgtc
    12961 cctgctgttt tcaattctaa aattaactca tgaattgttc gagaagttgt gggatctaga
    13021 cctgaggtcg gttcatccag aaagagtaca gcgggtttgt tgataagagc tcgtgctaaa
    13081 agcattcgtt gcctcattcc agtggataat tttcctgcta ccatcttgca actatcatat
    13141 aatcctactc gctttaacaa attatcaaca cgtaatttac taatattata aaatttacta
    13201 taaaaaagaa gattgttata cagagacatt ttctcataaa atccacttgt atcgctaacc
    13261 aatccaattc tctttaattc accgcttgtt aaattttgag atttttgtcc caaaataata
    13321 gattgtcctt tatcggcaag gagctgccca gtcagaatat taatcgttgt ggtctttcca
    13381 gaaccagatg gtcctaaaaa tccaaaaatc tgaccttctt taacagtgaa acttatatca
    13441 tttaaagcta ttttatcacc aaaacttttt gataaatggc taacttcaat catactcatt
    13501 gcccctcctt tatattctac atttttactt aacatctatt tacttagctt tatcaaataa
    13561 acgtcttaaa aaaaacaata acattaagca tataacc
//
LOCUS       DAVLBN010000053        13574 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLBN010000053 DAVLBN010000000
VERSION     DAVLBN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.053"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(3..848)
                     /locus_tag="VXC24_001647"
     CDS             complement(3..848)
                     /locus_tag="VXC24_001647"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0493734.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1104..2131
                     /locus_tag="VXC24_001648"
                     /pseudo
     CDS             1104..2131
                     /locus_tag="VXC24_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2432..4321)
                     /locus_tag="VXC24_001649"
     CDS             complement(2432..4321)
                     /locus_tag="VXC24_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0493735.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4459..6024
                     /locus_tag="VXC24_001650"
     CDS             4459..6024
                     /locus_tag="VXC24_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0493736.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6024..6764
                     /locus_tag="VXC24_001651"
     CDS             6024..6764
                     /locus_tag="VXC24_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0493737.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6873..7088)
                     /locus_tag="VXC24_001652"
     CDS             complement(6873..7088)
                     /locus_tag="VXC24_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493738.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(7972..9222)
                     /gene="ilvA"
                     /locus_tag="VXC24_001653"
     CDS             complement(7972..9222)
                     /gene="ilvA"
                     /locus_tag="VXC24_001653"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0493739.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(9272..9628)
                     /locus_tag="VXC24_001654"
     CDS             complement(9272..9628)
                     /locus_tag="VXC24_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0493740.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(9866..10102)
                     /locus_tag="VXC24_001655"
     CDS             complement(9866..10102)
                     /locus_tag="VXC24_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493741.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(10209..11231)
                     /gene="ilvC"
                     /locus_tag="VXC24_001656"
     CDS             complement(10209..11231)
                     /gene="ilvC"
                     /locus_tag="VXC24_001656"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0493742.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(11297..11773)
                     /gene="ilvN"
                     /locus_tag="VXC24_001657"
     CDS             complement(11297..11773)
                     /gene="ilvN"
                     /locus_tag="VXC24_001657"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0493743.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(11766..13466)
                     /locus_tag="VXC24_001658"
     CDS             complement(11766..13466)
                     /locus_tag="VXC24_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0493744.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         4161 a         3056 c         2358 g         3999 t
ORIGIN      
        1 tcttatacaa ataaacggac aaaactgtaa agtagcaaaa cactaccaag cacgatacgg
       61 tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc
      121 accatgctga ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag
      181 ctcaagagtt ctccggcttt cacaaatttg aaaatcttta aggcactagc tccaaacata
      241 acgggaatcc caagatagaa ggtaaattct gtcacaactg aacgactggt tccatttaac
      301 aaaccaccga caatcgttgc acctgaacgg ctagtccctg gtaaaagagc aagaacttgg
      361 aagagtccga tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt tacacttggc
      421 tcgatagcac acgctttatt gcgcttttcc aaatagatga aggcaacccc gtagataatc
      481 aacatgagag caactgaaac catgttatgg aagtgggtat caaaccaatc atcaaattta
      541 aagacaccaa gtaaaggtaa agtagcaatc aagaccttca accatagtct ccaagtctta
      601 cgaacttcct gtttgtcctt agtcggttta aaaggattga gcttgttaaa ataaatcacc
      661 ataactgcta aaatagcacc aagctgaatc acgacattaa acatggacat aaaggcttca
      721 ttttgatttt ggtattggat aaactcctct gctaaaatca agtgacctgt actggaaatc
      781 ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa aatttcaata
      841 agatacatat atttctcctt atattatatt taacgcagtt agctactgcc aaagcccaag
      901 tggtatactt ggaataagcc actgtggatt agttcatttc ctccaatcgc ttgacgattt
      961 ccgaaaggat ctaaccacag ctttttgttt caattggtaa tgagtttgat aacgcataga
     1021 cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag tagacttgaa
     1081 atactatatc tggaggtact cccatgcttt atgtgggcat tgatgtcgct aaaaataaac
     1141 acgatgttac agccttgaat gttcgaggaa aactgttctt aaaccactca ctttttcaaa
     1201 taataaagct ggttttgaac tattagatct gtctcttcga cagctcaacc aagactgtct
     1261 catcgctctt gaagataccg gacattatgc ctttaatcta ctgaacttcc tgcatgaaca
     1321 aggatataaa gtttacacct acactccttt gctcatcaag gaatttgcca aatcattatc
     1381 acttcgcaag actaaaacgg ataagaaaga cgctcatggc atcgctctta aacttctttc
     1441 tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagaactaa aaatactggc
     1501 tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat acactcgttg
     1561 tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag aatataccta
     1621 ccaactcttg acatgctacc ctaatcctca gaaaaggctt gaggcaggat ttgataagct
     1681 gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag tcgcacctcg
     1741 ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaaaca tcaaacatta
     1801 caagaggctc attgacaagg cggaaaaatg tgtcaatgac ttgatggctg agttcaactc
     1861 ggtcatcacg acggttactg ggattgggaa tcgtttaggg gcggtcattt tagccgagat
     1921 tcaaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg gactggattc
     1981 ttctatttat cagtcaggtc agattgattt agctggaaga atggtcaaac ggggttctcc
     2041 tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt cacctgcttt
     2101 taaggcctat cttaagacta agttagaata agaaaaacat tacaatgtag ccatcatcca
     2161 ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct gccatttgac
     2221 gaacaaaaag tgatgtaatt tctgaaatca acacaggatt acctttgaaa aaatggactt
     2281 tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt gaaataagaa
     2341 atagtttaga taaaattatt gacttttctt atagtttgtc tttcttctat cttccattat
     2401 atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg ccgccacctc
     2461 cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag taggtacttg
     2521 ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa aacatactgt
     2581 gccagccata agctacatag agattgatat ctggattttc aacttgaatc tgatgaacct
     2641 tcatcaaatg actaaccttg tccgcatagc caagtaaggt tgcatagacc aagagacgat
     2701 tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca cgtaacatat
     2761 tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga acaccatcac
     2821 gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct agaaaaccaa
     2881 gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag aacaaaccaa
     2941 atccgataaa taggggcagg atagtcaagg cacccatacc cacttgcaag gccttttccc
     3001 caccagttaa aggacgataa taatctggga gcccccagaa ggaaactcgt tttctcactc
     3061 cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc cctcttgctt
     3121 gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat accttgtaat
     3181 ccgcaaacaa attggaaaga gtttcttctt ttttacctga aaaggctaga tttagacagt
     3241 ctctctcaaa gcttgacaaa ccatcttctt ttactagcct caaaccaact gcatctcctt
     3301 ctgaaatgat agagacattc ccacggtcta tcacatctag caaggtagct tgaataagtt
     3361 gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc aaggaggtcg
     3421 agtagactgc ttctgataaa accataggct ctaattccat tggtggttca tagagacgat
     3481 gatttttggc atatttgact gaaggagtgg tctttcttct ataaataaaa tagaagcaga
     3541 cactcaataa caaggagatg gaaaggatcg aagggaggac ccaagtaagt agttgtttac
     3601 tttgctcttt ttctctaaca atcgagtctt ctatcttatt aaactcttct aatcgattcc
     3661 ctttcaatcc ctgatcccta gcgctagcaa aatcggtccg aggccaatag gcatgcaact
     3721 caactccacg cttagccgga agattgtcta aacggatagt ataatcaagg ttactctttt
     3781 caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca gtccccttgt
     3841 ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc agaggttgcc
     3901 aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc cagacgaggt
     3961 caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta taaccatccg
     4021 cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc gcggcctgaa
     4081 tctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt ccaagtccca
     4141 cgatttggcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta aactctgccg
     4201 tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa tcaatggcaa
     4261 aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa gtttttttca
     4321 tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta agtaaaggct
     4381 tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat tttttaatag
     4441 atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag tctcttgctg
     4501 atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg gatggaagca
     4561 gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt caaaatcgat
     4621 gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat cgctaaggac
     4681 ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc tgcccttact
     4741 tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg caaacaagaa
     4801 attgcctttt cgagcagtta ctacactagc gaaccagttc tactggtcaa aaaagattct
     4861 gcctatgcaa atgctaaatc tttggatgac tttaatggtg cgaaaatcac ttctcaacaa
     4921 ggtgtctacc tttatgactt gattgcacaa atcacaggtg ctaaaaaaga aacagccatg
     4981 ggagacttcg ctcaaatgcg ccaagctctt gaggctggtg tcatcgacgc ctatgtttct
     5041 gaacgcccag aagctctgac tgccgaagcc gctaactcta agttcaagat ggtccaagta
     5101 gaaccaggtt tcaaaactgg ggaagaagat acagctatcg ccattggact tcgtaaagat
     5161 gacactcgta ttagccaaat caatgccagc attgaaacca tttcaaagga cgaccaagtt
     5221 gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac tgaagagact
     5281 agcagtagtt tctttagcca agttgctaaa attctttctg aaaactggca acaactcttg
     5341 cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcacagg tctcattatt
     5401 ggacttgcca ttggtgtttt ccgtactgct cctctctctg aaaacaaagc catttacggc
     5461 ctacaaaaac tagtcggctg gattctcaac gtctacattg aaattttccg tggtacgcca
     5521 atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg gatcaacctt
     5581 gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta catgactgaa
     5641 atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc gactgctctt
     5701 ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt ccgtaacatc
     5761 ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt attgaacgtt
     5821 atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac ctatcaatac
     5881 ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac cgtaacacgt
     5941 atcctacgat ttatcgagcg ccgaatggac atggatacct atactacagg tgctaaccaa
     6001 atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa cacctcaaaa
     6061 aatcctatgg acaaaacgaa gtgctaaaag acatttcact cactgtccac aagggagagg
     6121 tcatctctat catcggaagc tctggaagcg gaaaatcgac cttcctacgc tccattaacc
     6181 tacttgaaac accaactgat ggacaaatcc tttatcatgg acaaaacgtc ctcgaaaaag
     6241 gctatgacct cacgcaatac cgtgaaaagt tggggatggt tttccaatcc tttaacctct
     6301 ttgaaaatct caatgttctt gaaaacacaa tcgtcgctca gacaactgtc ctaaaacgcg
     6361 aacgcacaga agctgaaaag attgccaaag aaaacctgga aaaggtcggc atgggagaac
     6421 gctactggca agccaaacca aaacaactct caggtggtca aaaacaacgt gtggccatcg
     6481 ctcgtgccct ctccatgaat ccggacgcta ttctctttga tgaaccaaca tcagctctcg
     6541 atccagaaat ggttggagaa gtcctcaaaa tcatgcagga cctggctcag gaaggcttga
     6601 ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac cgtgttatct
     6661 ttatggataa gggcgtgatc gctgaagaag gtaaaccaga agacctcttc accaatccta
     6721 aagaagaccg aacaaaagag ttccttcaac gctatctcaa ataaaaagaa aaggctgcat
     6781 caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta tctctactac
     6841 ttgaaggtca agaatccgcc gttatccaaa gattaatctt caaatttttc ataatttttt
     6901 tcatagaaat caattaggcc tagggctgtt tcaaatgaaa tattttttac ttttgcacga
     6961 ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga gatacggtag
     7021 cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc aaagtttgac
     7081 ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac gtttttacta
     7141 cttttgtcaa taaaaaaaca tgtattcaac gaaaataatt agttcagaat tttagcttca
     7201 gaattttctt acttcctttt tgaatccgat aatatatagg ttttactagt ctctacacca
     7261 taaatatttg ctaataaaaa tactgtatta ttaccctctt aaggtgcgaa attattcaag
     7321 ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt taagaactga
     7381 agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac tcctatcttt
     7441 cttcctcaat aaatcatctg agagataggt attccttatg tccttcaaat tcatcactcc
     7501 tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc atccttaata
     7561 aagatgacaa gacagataag ctcagttaat tacttatata tctttttaat atggtatatt
     7621 tgtcaacaaa aagaaatcaa atcatacctt atactcaatg aaaatcaaag agcaaactag
     7681 gaagctagcc gcaagttgct caaaacactg ttttgaggtt gcagatagag ctaacgtggt
     7741 ttgaagagat tttcgaagag tattaaagac agtgtgacta tgcttgtcaa tagataggaa
     7801 atcaaaatga aggatggaaa tctgagccaa acatcataag tgctataatg aacagaagta
     7861 agaattgcac gataagtttt ctaaaaccat aggaatcgtc ccctttcttc atcttcatta
     7921 tagcacatat acatcagttg tacaaataat atgatatttt tttattagtc ctcagacaag
     7981 catattataa agcgtttcat taccatttaa gttaatataa gctggatcaa aaccttccat
     8041 tctacgaatc aaacctgcat aatcatgctt atctgctaaa gcgatcccaa ttaatactgg
     8101 gcctgttccc ttgctagctc gtttgatata ctcaaaacgt gtgatatcat catttggccc
     8161 caggatatca tttacaaact cacgcaaagc tcctggacgt tgtgggaaat tgaccacaaa
     8221 gtaatgtttg ataccatcat aaatcaaggc acgctcttcc atttctggca tacggttgat
     8281 atcattattt cctccagaaa tgatacaaca aatggttttc cccttaatat attcagctaa
     8341 aacctctaaa gaggcgatac tagctgctcc agcaggttct gcgactatcc cttgcttaga
     8401 gtaaaggtca atcaaggttt cagaaatcaa tccctcatcg acacctacca aagtttgaat
     8461 atgttgacga gttgcttcat aggtcaactg acctaccttt tgcacagcaa tcccatccgc
     8521 aaatttatca atttccttga gtttgactgg acctccagcc tcaaaggcag ctttcatgga
     8581 acgcgctcca ttcgcctcta ctccgataac ctcaatctct ggacttgttt ccttgatata
     8641 ggtagaaacc ccggcaatga gaccgccacc accaacagga accaagacag catcaaaatc
     8701 aatcgattct tttcgagctt cttctaaaat ctcataagca actgttcctt gacctgcttg
     8761 aacatgagca tcatcaaaag gatcaataaa ggtacgattt tcagagactg taaattcttg
     8821 agctgctttg gctgaggcat caaaggtatc tccaactagt ttaatagtta caaaatcccc
     8881 accaaaaaag cgaacctgac caatcttttg ttgtggcgta gtaatgggca taaagatagt
     8941 agcaggaatt ttcatttcat tacaagtata ggctactccc tgcgcatgat ttcccgcaga
     9001 agcgcagact accccacgtt cacgttcttc cttgctgagc tgggaaatgg cataataggc
     9061 accacgaatt ttaaaggagc gaacacgctg ggcattttct tttttcaaat aaatcttagc
     9121 accatacttc tccgataaat aatgatcgta atccagtgga gtattcacaa ccacaccgtt
     9181 caagaccttg tgagccttga ttatatcttt tgaacttaac atataaaacc tctttttcta
     9241 taaaaaacag tcactaatga ctgtttttta gttattcatc tccgaaaact tcagtaacac
     9301 tttcatggta tttatgagcc atacgaatcg aaaactcttt aggaagttca taacgatttg
     9361 tggaaatcca atcatataac cattctacca aactttcttc actatcatta cgatggaaga
     9421 taaaatagtt taaaatttct ttatattcta catcattcaa atccaacgtg tctacaaatt
     9481 gactacgagg aacaaaatta gaatctaatt ttcttagttg atctgtcaat tctcccaatt
     9541 gtaaatccaa ctgaaaaaat agtttttgca gttgcctatc agtttcatca catcctgtct
     9601 tgatagaaaa caaattggta atattcatat gatttcaacc cctaaataag tacatctaat
     9661 atcccacgaa tagctgaagc taaagttttc gcagtccagt catttaaacc cgattctttc
     9721 aatccagatg caataatttg ctctatttga tataaaccgc catctatcgt ctcatttatt
     9781 ctgcgaagag gaccttcaat ataggataaa gcttctccga atctaacagc tgatttaggt
     9841 cctaatgatt taccaactat atttgttaat gttttttatt tctcaaaatc catttcgcta
     9901 tataacgagc agatttagtc gcaccagctc tctcaaacgg agaatgaatt tcaagacctt
     9961 cttctctaga tatttgtgcc aatttgaaga attgttcaaa gttcatatgc aacctaccat
    10021 cttcaaaatt agcatcatca taaatgttaa ttacagcatt ttcatcatac gaccaatctg
    10081 ctttattttg gtctgctagc actattaccg acggtgtaat tacattatac aactagaacc
    10141 aataataacg atgcagtttt tctcataatc tttttcataa aatcatctcc agcgctatat
    10201 atttctaatt agttatagat tttgaatgca tcatcgtcgt ttttaccaac gaatggcatt
    10261 gctttacgca attctgcacc aactttttca atttcaaggt tagctgcttg ttcacggtaa
    10321 gcagtcaatt ttggacgtcc agctttatag tcatttacaa agtcatttgc aaatttacca
    10381 ttttggatgt ctgccaagac agccttcata ttttctttaa cttgttcagt gattacacgt
    10441 ggacctgata catagtcacc gtattcagca gtgtttgaaa tagattgacg cattttcttg
    10501 aatccacctt cgtagatcaa gtcaacgatc aatttcattt cgtgaagaac ttcaaagtaa
    10561 gccaattctg gagcgtaacc tgcttctgtc aagacttcga aacctgcttc gataagggca
    10621 gtcaaaccac cacaaagtac agcttgttca ccaaacaaat cttcttcagt ttcttctttg
    10681 taagttgttt caagaagacc tacacgagcc gctccaacac ctttacacca gtccatagca
    10741 atgtttttag catttcctgt tgcatcttgg tatactgcat aaagagctgg aacaccaaat
    10801 ccttcttcgt aagtacgacg taccaagtgt cctggtcctt taggagcaca catgaagaca
    10861 tctacatccg caggaacttt gataaattca aagtggatgt tgaaaccatg ggcaaatcca
    10921 actgcgtttc cagcttccaa gtttggagcg atttctgctt cgtacaattc ttgttgaatt
    10981 tcgtctggcg ccaagatcat gataacatca gccaacttag tagcttctgc tactgtgtaa
    11041 gtatcaaatc catcttcttt tgctttatca aaagatttac ctggacgtac accgataata
    11101 acgtcacgac ctgaatcacg caagttttga gcatgcgcat gtccttgtga accataaccg
    11161 ataacggcga tttttttacc gtcaagtgct gctactttaa catctttttc atattccatt
    11221 tgaactgtca tagcttttct ctcttttcta ttatttattg ccttttaggc tggtttaata
    11281 aatttaagtt ggatttttaa tcgcgggtaa atccagttgc acccgttcga gcaatattgc
    11341 gaataccgta tgggcgaatg actcgcaata gggcttcgct cttttctgca tttcccgtca
    11401 tctgaatggt aatcgagctt ggcgctacgt ctaccactgt tgcacggaaa ggttgaataa
    11461 tcgctaaaat ctcagctctc ttctcagctg gcgctgacat cttaaccaaa atcacctcgc
    11521 gctccaaatg aggcttgtct gtaatatctc gaatgcgaat cacatcaatc tgacgattga
    11581 gctgtttgat gatttgctcc acttcatcat gagaagcaac atcaataata atagtgatac
    11641 gcgatacatt cggatcttct gttgctccaa cagagatgct ttcaatatta acctgacgac
    11701 gagataggac acctgtaaag cgattgagga ctcctgaacg attttgtagt tttgctgtta
    11761 acattctacg catggaactg cacccccaac atctcatgat tactcttacc agccggtacc
    11821 attggtaaca cctgttcctt acgagaaata tctacctcaa ttagcatagg aacatcctca
    11881 gtgatgactt caaggtcttg agccaaggtc tcaggattat caaacttata gtttttaata
    11941 ccataagcct gcgccatcaa ttggaaatca ggaagggtat caaagaccga ctctgatgtt
    12001 ctgccttcat agaaggattc ctgccactgg cgaaccattc caagtgaatg attgttcagc
    12061 ataaccacct tgattggcac cttgtaaata ttcaaaatag ccaactcctg gttggtcatt
    12121 tggaaaccac catccccaac aaacaagact acttccttat ctgggttagc aattttagca
    12181 ccgattgctg ctggaattcc aaagcccatt gttcccaaac cacctgaagt cactaactga
    12241 cgttcatttt ggtagggata atactgagct gtccacattt ggtgttgacc aacgtctgtt
    12301 accacaatgg catctccatt cgtcaattca ccaattcgtt caataactgc ttgcggttga
    12361 accacacgct ctttcttgtc ataagaacga acacgattct tgtctttagt gactttctca
    12421 atccactttt cagtgttgtt gtgaactgtt ggttctgcta gcaacatttg caaggccttc
    12481 ttagcatctc caactacagg aatgtctgca ctgataatct tgccaatctc agctgggtca
    12541 atatcaatgt gggcaacctt agcattctta gcgaaagtct taggattccc cgtcaaacgg
    12601 tcatcgaaac gagaaccaat actaatcata aagtccgctt ccgtcatggc aatatttgct
    12661 gcgaatgacc cgtgcatgcc tcccattcca agaaagagtg ggtgactcgt tgcaatcgtt
    12721 ccttgtccca aaagactggt taccactgga atttgatagc gttctgcaaa ttcatttagt
    12781 tccgtagcag cctcagcata actaattcca ccaccagcta acaagactgg ctttttagcc
    12841 ttggacaatt gcttcaagat tttcttgatt tgcatatcat tcggctcaag agtcggctga
    12901 taacttggta aattcacttc tggtgaataa atgaagtctg tttctaaagc agatatatct
    12961 tttggtaggt caattacaac tggccctgga cggcctgtag ttgcgatatg gacagcttcc
    13021 gtaatgatac gcggaatatc agctgtctca cgaacttggt aattgtactt agtgattggc
    13081 atggtaattc ccacgatgtc tgcctcctga aaggcatcct tcccaatccc tgctcgcgcc
    13141 acctgacctg taaagaccaa aaggggaacg ctatcgctca tggcatccgc aatccctgta
    13201 atggcatttg ttgctcctgg tccactagtg acgacggcaa cacccaactt tccagttgat
    13261 ttggcataac cttcagcttc atgcaaacaa ccttgctcat ggcgccctag aatgtggcga
    13321 atgcctttaa aattatatat cgcatcataa aaaggcaaaa ccgcaccacc aggataacca
    13381 aagatggtat caactcctaa atcacgaagt gtttccaaaa ctaggtccga ccccgtctta
    13441 ggagattcta aactgatttt ctccattgtt cccctttctt tcctcttaaa aataacttgt
    13501 tactatcata ccattttttc aaaatttttc aagataaaag aagaaatttt ctgaattttc
    13561 tattttaacg ttta
//
LOCUS       DAVLBN010000054        12956 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLBN010000054 DAVLBN010000000
VERSION     DAVLBN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.054"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            157..5136
                     /locus_tag="VXC24_001659"
     CDS             157..5136
                     /locus_tag="VXC24_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0493745.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            5226..6422
                     /locus_tag="VXC24_001660"
     CDS             5226..6422
                     /locus_tag="VXC24_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0493746.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            6558..7085
                     /locus_tag="VXC24_001661"
     CDS             6558..7085
                     /locus_tag="VXC24_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0493747.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            7162..7518
                     /gene="glnR"
                     /locus_tag="VXC24_001662"
     CDS             7162..7518
                     /gene="glnR"
                     /locus_tag="VXC24_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0493748.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7555..8901
                     /gene="glnA"
                     /locus_tag="VXC24_001663"
     CDS             7555..8901
                     /gene="glnA"
                     /locus_tag="VXC24_001663"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0493749.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8997..9116)
                     /locus_tag="VXC24_001664"
     CDS             complement(8997..9116)
                     /locus_tag="VXC24_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0493750.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            9661..10980
                     /locus_tag="VXC24_001665"
     CDS             9661..10980
                     /locus_tag="VXC24_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0493751.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKF
                     ASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDIS
                     PKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGD
                     SKDAIKGKTLNSTSISELLIPISNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(10934..11533)
                     /locus_tag="VXC24_001666"
     CDS             complement(10934..11533)
                     /locus_tag="VXC24_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0493752.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQL"
     gene            complement(11544..12341)
                     /gene="psrA"
                     /locus_tag="VXC24_001667"
     CDS             complement(11544..12341)
                     /gene="psrA"
                     /locus_tag="VXC24_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV0493753.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            complement(12398..>12956)
                     /locus_tag="VXC24_001668"
     CDS             complement(12398..>12956)
                     /locus_tag="VXC24_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0493754.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPKTVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
BASE COUNT         4270 a         2306 c         2611 g         3769 t
ORIGIN      
        1 aaccttattt tagatttatg aaagcagcta ttgttttttg tctaaaaatg ttttaggata
       61 aaaatgtgat tatcatggtt ctagagtttg ataaaaaact acagaatata aagcgctttc
      121 ttgaaaacaa caaaatcaat cttttaggag gagaaaatga agaatccatt ttttgaaaga
      181 cgttgtcgtt acagtattcg taagttatca gtaggagcct gctcgctgat gattggtgct
      241 gttttatttg ctggtccagc cttggctgaa gaaactgcag ttcctgaaaa tagcggagct
      301 aatacagagc ttgtttcagg agagagtgag cattcgacca atgaagctga taagcagaat
      361 gaaggggaac atgctagaga aaacaagcta gaaaaggcag aaggagtagc gatagcatct
      421 gaaactgctt cgccagcaag caatgaagct gcaactactg aaactgcaga agcagctagc
      481 gcagctaaac cagaggaaaa agcaagtgag gtggttgcag aaacaccatc tgcagaagca
      541 aaacctaagt ctgacaagga aacagaagca aagcccgaag caactaacca aggggatgag
      601 tctaaaccag cagcagaagc taataagact gaaaaagaag tccagccaga tgtccctaaa
      661 aatacagaaa aaacattaaa accaaaggaa atcaaattta attcttggga agaattgtta
      721 aaatgggaac caggtgctcg tgaagacgat gctattaacc gcggatctgt tgtcctcgct
      781 tcacgtcgga caggtcattt agtcaatgaa aaagctagca aggaagcaaa agttcaagcc
      841 ttatcaaaca ccaattctaa agcaaaagac catgcttctg ttggtggaga agagttcaag
      901 gcctatgctt ttgactattg gcaatatcta gattcaatgg tcttctggga aggtctcgta
      961 ccaactcctg acgttattga tgcaggtcac cgtaacgggg ttcctgtata cggtacactc
     1021 ttcttcaact ggtctaatag tattgcagat caagaaagat ttgctgaagc tttgaagcaa
     1081 gacgcagatg gtagcttccc aattgcccgt aaattggtag acatggcaaa gtattatggc
     1141 tatgatggct atttcatcaa ccaagaaaca actggagatt tggttaaacc tcttggagaa
     1201 aagatgcgcc agtttatgct ctatagcaag gaatatgctg ctaaggtaaa ccatccaatc
     1261 aagtattctt ggtatgatgc catgacctat aactatggac gttaccatca agatggtttg
     1321 ggagaataca actaccaatt catgcaacca gaaggagata aggttccggc agataacttc
     1381 tttgctaact ttaactggga taaggctaaa aatgattaca ctattgcaac tgccaactgg
     1441 attggtcgta atccttatga tgtatttgca ggtttggaat tgcaacaggg tggttcctac
     1501 aagacaaagg ttaagtggaa tgacatttta gacgaaaatg ggaaattgcg cctttctctt
     1561 ggtttatttg ccccagatac cattacaagt ttaggaaaaa ctggtgaaga ttatcataaa
     1621 aatgaagata tcttctttac aggttatcaa ggagacccca ctggccaaaa accaggtgac
     1681 aaagattggt atggtattgc taacctagtt gcggaccgta cgccagcggt aggtaatact
     1741 tttactactt cttttaatac aggtcatggt aaaaaatggt tcgtagatgg taaggtttct
     1801 aaggattctg agtggaatta tcgttcagta tcaggtgttc ttccaacatg gcgctggtgg
     1861 cagacttcaa caggggaaaa acttcgtgca gaatatgatt ttacagatgc ctataatggc
     1921 ggaaattccc ttaaattctc tggtgatgta gctggtaaga cagatcagga tgtgagactt
     1981 tattctacta agttagaagt aactgagaag accaaacttc gtgttgccca caagggagga
     2041 aaaggttcta aagtttatat ggcattctct acaactccag actacaaatt cgatgatgca
     2101 gatgcatgga aagagctaac cctttctgac aactggacaa atgaagaatt tgatcttagc
     2161 tcactagcgg gtaaaaccat ctatgcagtc aaactatttt tcgagcatga aggtgctgta
     2221 aaagattatc agtttaacct aggacaatta actatctcgg acaatcacca agagccacaa
     2281 tcgccgacaa gcttttctgt agtgaaacaa tctcttaaaa atgcccaaga agcggaagca
     2341 gttgtgcaat ttaaaggcaa caaggatgca gatttctatg aagtttatga aaaagatgga
     2401 gacagctgga aattactaac tggctcatct tctacaacta tttatctacc aaaagttagc
     2461 cgctcagcaa gtgctcaggg tacaactcaa gaactgaagg ttgtagcagt cggtaaaaat
     2521 ggagttcgtt cagaagctgc aaccacaacc tttgattggg gtatgactgt aaaagatacc
     2581 agcctaccaa aaccactagc tgaaaatatc gttccaggtg caacagttat tgatagtact
     2641 ttccctaaga ctgaaggtgg agaaggtatt gaaggtatgt tgaacggtac cattactagc
     2701 ttgtcagata aatggtcttc agctcagttg agtggtagtg tggatattcg tttgaccaag
     2761 ccacgtaccg ttgttagatg ggtcatggat catgcaggag ctggtggtga gtctgttaac
     2821 gatggcttga tgaacactaa agactttgac ctttattata aagatgcaga tggtgagtgg
     2881 aagctagcta aggaagtccg tggtaacaaa gcacacgtga cagatatcac tcttgataaa
     2941 ccaatcactg ctcaagactg gcgcttgaat gttgtcactt ctgacaatgg aactccatgg
     3001 aaggctattc gtatctataa ctggaaaatg tatgaaaagc ttgatactga gagtgtcaat
     3061 attccgatgg ccaaggctgc agcccgttct ctaggcaata acaaggtaca agttggcttt
     3121 gcagatgtac cggctggagc aactattacc gtttatgata atccaaattc tcaaactccg
     3181 ctcgcaacct tgaagagcga agttggagga gacctagcaa gtgcaccatt ggatttgaca
     3241 aatcaatctg gtcttcttta ttatcgtacc cagttgccag gcaaggaaat tagtaatgtc
     3301 ctagcagttt ccgttccaaa agatgacaga agaatcaagt cagtcagcct agaaacagga
     3361 cctaagaaaa caagctacgc cgaaggggag gatttggacc ttagaggtgg tgttcttcga
     3421 gttcagtatg aaggaggaac tgaggacgaa ctcattcgcc taactcacgc aggtgtatca
     3481 gtatcaggtt ttgatacgca tcataaggga gaacagaatc ttactctcca atatttggga
     3541 caaccggtaa atgctaattt gtcagtgact gtcactggcc aagacgaagc aagtccgaaa
     3601 actattttgg gaattgaagt aagtcaggaa ccgaaaaaag attacctagt tggtgatagc
     3661 ttagacttgt ctgaaggacg ctttgcagtg gcttatagca atgacaccat ggaagaacat
     3721 tcctttactg atgagggagt tgaaatttct ggttacgatg ctcaaaagac tggtcgtcaa
     3781 accttgacgc ttcattacca aggccatgaa gttagctttg atgttttggt atctccaaaa
     3841 gcagcattga acgatgagta cctcaaacaa aaattagcag aagttgaagc tgctaagaac
     3901 aaggtggtct ataactttgc ttcatcagaa gtaaaagaag ccttcttgaa agcaattgaa
     3961 gcggccgaac aagtgttgaa agaccatgaa actagcaccc aagatcaagt caatgaccga
     4021 cttaataaat tgacagaagc tcataaagct ctgaatggtc aagagaaatt tacggaagaa
     4081 aagacagagc ttgatcgctt aacaggtgag gttcaagaac tcttggctgc caaaccaaac
     4141 catccttcag gttctgccct agctccgctt cttgagaaaa acaaggcctt ggttgaaaaa
     4201 gtagatttga gtccagaaga gcttacaaca gcgaaacaga gtctaaaaga tctggttgct
     4261 ttattgaaag aagacaagcc agcagtcttt tctgatagta aaacaggtgt tgaagtacac
     4321 ttctcaaata aagagaagac tgtcatcaag ggtttgaaag tagagcgtgt tcaagcaagt
     4381 gctgaagaga agaaatactt tgctggagaa gatgctcatg tctttgaaat agaaggtttg
     4441 gatgaaaaag gtcaagatgt tgatctctct tacgcttcta ttgtgaaaat cccaattgaa
     4501 aaagataaga aagttaagaa agtatttttc ttacctgaag gcaaagaggc agtagaattg
     4561 acttttgaac aaacggatag tcatgttatc tttacagcac cacactttac tcattatgcc
     4621 tttgtttatg aatctgctga aaaaccacaa cctgctaaac cagcaccaca aaacaaagtc
     4681 cttccaaaac ctacttatca accgacttct gatcaacaaa aggctcctaa attggaagtt
     4741 caagaggaaa aggttgcctt tcatcgtcaa gagcatgaaa atgctgagat gctagttggg
     4801 gaacaacgag tcatcataca gggacgagat ggactgttaa gacatgtctt tgaagttgat
     4861 gaaaacggtc agcgtcgtct tcgttcaaca gaagtcatcc aagaagcgat tccagaaatt
     4921 gttgaaattg gaacaaaagt aaaaacagta ccagcagtag tagctacaca ggaaaaacca
     4981 gctcaaaata cagcagttaa atcagaagaa gcaagcaaac aattgccaaa tacaggaaca
     5041 gctgatgcta atgaagccct aatagcaggc ttagccagcc tcggtcttgc tagtttagcc
     5101 ttgaccttga gacggaaaag agaagataaa gattaaatat cgaaaaatct tgtgaaatct
     5161 ttccttatat ttccaaagtg tgatataata gtttcgaata aaataaataa aggagttttt
     5221 gtaacatggc aaaacttact gttaaagacg ttgacttgaa aggtaaaaaa gtcctcgttc
     5281 gtgttgactt caacgtacca ttgaaagatg gcgtaatcac taacgataac cgtatcacag
     5341 cagctcttcc aactattaag tacatcatcg aacaaggtgg acgtgcaatt cttttctctc
     5401 accttggacg tgtgaaagaa gaagctgata aagctggtaa atcacttgct cctgtagcag
     5461 ctgacttggc agcaaaactt ggtcaagatg ttgttttccc aggtgtcact cgtggtgctg
     5521 aattggaagc ggcaatcaac gctcttgaag atggacaagt tctcttggtt gaaaacactc
     5581 gttacgaaga tgttgacggc aagaaagaat ctaaaaacga tcctgaactt ggtaaatact
     5641 gggcatcact tggagatggt atcttcgtaa acgatgcatt cggtacagct caccgtgcac
     5701 acgcatctaa cgttggtatc tcagcaaacg ttgaaaaagc agttgctggt ttccttcttg
     5761 aaaacgaaat tgcctacatc caagaagcag ttgaaactcc agaacgtcca ttcgtggcta
     5821 tccttggtgg ttcaaaagtt tcagacaaga tcggtgttat cgaaaacttg cttgaaaaag
     5881 ctgataaagt ccttatcggt ggtgggatga cttacacatt ctacaaagca caaggtatcg
     5941 aaatcggtaa ctcacttgta gaagaagaca aattggatgt tgcgaaagct cttcttgaaa
     6001 aagcaaatgg taaattgatc ttgccagttg actcaaaaga agctaacgca tttgctggtt
     6061 acactgaagt gcgtgacact gaaggtgaag cagtttctga aggcttcctt ggtcttgaca
     6121 tcggtccaaa atctatcgcc aaatttgacg aagctttgac tggtgccaaa acagttgtat
     6181 ggaacggacc tatgggtgta tttgaaaacc cagatttcca agctggtaca atcggtgtga
     6241 tggacgctat cgtgaaacaa ccaggagtta aatcaatcat cggtggtggt gactcagctg
     6301 ccgcagcgat taaccttggc cgtgcagaca agttctcatg gattagtacg ggtggtggag
     6361 catcaatgga acttcttgaa ggtaaggttc ttccaggact tgcagccctg acagaaaaat
     6421 aagattttat aaacaaatca aagaagagag ggatgaaagt tcctcttttc ttttgcttaa
     6481 aataaaaacg cttcctctca actattactc ataaaaatca ccgatttatg ataaaatgga
     6541 aatagaaagt tgagattatg agttatttta aaaaatataa attcgataaa tcccagttca
     6601 aacttggtat gcgaaccttt aaaacaggta ttgctgtttt tctagttctc ttgatttttg
     6661 gcttttttgg ctggaaaggt cttcaaattg gtgctttgac agccgttttt agcctgaggg
     6721 agagttttga tgagagtgtt cattttggga cttcgcgtat tctaggaaat agtatcggtg
     6781 gactctatgc cttggtcttc ttcttattaa ataccttttt ccacgaagcc ttttgggtga
     6841 ccttggtagt tgttccaatc tgcaccatgt taaccattat gacaaatgta gccatgaata
     6901 acaaagcagg ggttattggt ggtgtagcag ctatgttaat cattacccta tcaattccaa
     6961 gtggtgagac aatttcgtac gtgtttgtgc gtgtatcaga aacgtttatg ggagtttttg
     7021 tcgcaattat cgtaaattac gatattgatc gtgttcgtct ctttttagag aaaaaagaaa
     7081 aataatgtta cattttataa cattatcaat tgacgtttgt ctttttttag actataatag
     7141 acagaaagaa ggaaattgta aatgaaggaa aaagaatttc gccgaaatat ggctgttttt
     7201 cctatcggca gtgttatgaa gttgaccgat ctatcggcgc gtcagattcg ttattatgaa
     7261 gatcaagagt tgatcaagcc cgatcgaaac gaaggaaatc gtcgcatgta ttccttgaat
     7321 gacatggatc gtctgcttga aatcaaagat tatatctctg aaggttataa tatcgctgcc
     7381 attaagaaaa aatatgctga acgtgaagcg aaatccaaga aagcggttag tcagactgaa
     7441 gtacgtcgtg cacttcacaa tgaactcctc caacaggggc gttttgcttc agtacagtca
     7501 ccttttggtc gcggttaggc aaccgcaagt agtcatagat taaggagaaa acttatgcca
     7561 atcacagctg cagatattcg tcgtgaagtc aaggaaaaaa atgttacctt tattcgtctt
     7621 atgttctcag atattttggg aaccatgaaa aacgtcgaaa ttcctgctac agatgaacag
     7681 ttagataagg ttttgtcgaa caaggttatg tttgatggat cttctattga aggttttgta
     7741 cgtatcaatg agtcggatat gtacttgtac ccggacttgg atacatggac agtcttccct
     7801 tggggagatg aaaatggaag tgttgcaggt ctgatctgtg atgtctatac aacagaaggt
     7861 gaaccatttg cgggtgaccc tcgtggtaat ttgaaacgag ctcttcgtca catggaagaa
     7921 gttggattca aatccttcaa ccttggtcca gagccagaat tcttcctatt taagttggat
     7981 gaaaatgggg acccaacact tgaagtgaat gacaagggtg gctactttga tttggcacct
     8041 actgaccttg cggacaacac acgtcgtgag attgtgaatg tcttgaccaa aatgggattt
     8101 gaagtagaag cgagtcacca cgaggttgcg gttggacagc atgagattga ctttaagtac
     8161 gatgaagttc tccgtgcttg tgataagatt caaatcttta aacttgttgt taaaaccatt
     8221 gctcgcaaac acggacttta cgcaacattt atggcgaagc caaaatttgg tattgctggc
     8281 tcaggtatgc actgtaatat gtccttgttt gatgcagaag gaaataacgc cttctttgat
     8341 ccaaatgatc caaaaggaat gcagttgtca gaaacagctt accatttcct aggcggtttg
     8401 atcaagcatg cttacaacta tactgccatc atgaacccaa cagttaactc atacaaacgt
     8461 ttggttccag gttatgaagc gcctgtttac attgcttggg ctggtcgtaa ccgttcgcca
     8521 cttgtgcgcg tacctgcttc acgtggtatg ggaactcgtc ttgagttgcg ttcagtggat
     8581 ccaatggcga acccttacat tgctatggct gttcttttgg aagttggttt gtatggtatt
     8641 gaaaataaaa tcgaagcacc agctcctatc gaagaaaata tctacatcat gacagcagaa
     8701 gagcgcaagg aagctggtat tacagacctt ccatcaactc ttcacaacgc tttgaaagct
     8761 ttgacagaag atgaagtggt taaagctgct ctcggagatc acatctacac tagcttcctt
     8821 gaagccaaac gaatcgaatg ggcaagttat gcaaccttcg tttcacaatg ggaaattgat
     8881 aattatttag acctttacta atactaatat agaagaaaga ttgcctgtgg gtaaacagtc
     8941 acacagcagt ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat
     9001 ttatttttcg aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag
     9061 aagaaaatta aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa
     9121 acaagttact tcaaatcgaa atctacaagt ttactaactt ttgcaagctt caaaattaca
     9181 catctgtaaa tattttttcg aaagatatat ttgaagccat agtaaattga gactagaatg
     9241 gtacactaca tctgctaaaa atttctagaa actaatttaa ctttcctaat cgatttgttt
     9301 acatcttatt tcaatctact atattatctc aataaatgat gatggcgact gttttgtttg
     9361 tgcttgtcga tttttgaatc ctgatcgagc ggaagaatat ttctgccgag gttgccaagg
     9421 ggaaaatcct gaagatattg aattttatga tgaacaatta caggcagaaa aggtggaggt
     9481 tttgaatatt cgattggaag taaaaaattg aattatctac aatctcatca acaataaacc
     9541 tatttcaacc ccattatcta taggcgtatt tttacgcctt tttatatact tgaagcacat
     9601 aagaaacatt atgggaagtt tgctgatgga agtactcaag aaattgatgt tccttatgat
     9661 attcctgata cttgggagtg ggtgaggttt tctacattgg ttgaaattgt cagaggtggc
     9721 tctccacgac caatcaaaga ttatcttact tctgaagtag atggaataaa ttggataaaa
     9781 ataggtgata ctgaaaaggg tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa
     9841 tcagggctta acaaaactag atttgtaaaa aaaggtacat ttttgttaac taattctatg
     9901 agttttggta gaccttatat tttgaatgtt gatggtgcaa tacacgatgg atggttggct
     9961 atttcgaact atgaaaactc attaaataaa gattacctat tctatattct ttcatcaaat
    10021 gtagtttatt ctcaatttct atctctaatt agtggagctg ttgtgaaaaa cttgaatagt
    10081 gataaagttg cttctattct tatccctctc cccccactat ccgaacaaca acgcataata
    10141 gaagcaatcg aatcagcttt agaaaaagta gatgaatatg ctgaaagtta taatagacta
    10201 gaacagctag ataaagaatt tccagataaa ctaaaaaaat ctattcttca atatgctatg
    10261 caaggaaaat tagttgaaca agacccaaat gatgaatcag tcgaagtttt acttgaaaaa
    10321 atacgagcag aaaaacaaaa actctttgaa gaaggcaaga ttaaaaagaa agatttggac
    10381 atttctattg tttcccaagg agatgataac tcttattatg ggaacaaaga cgaaacaacc
    10441 tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc tagcctagtt
    10501 aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg aactgaaata
    10561 ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatac gagagaatct
    10621 atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg aactttatta
    10681 atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc cactcataat
    10741 gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag agattactta
    10801 atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat caaagggaaa
    10861 acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca tgaagagatg
    10921 aaaagaatca ttttcaaagt tgatttactt tttcaaaaag tttctcaact ttttgagtaa
    10981 taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgctcagt gtagttttag
    11041 gaatattata taaagcttga cctgatagtt tagttaatgc tttcaattgt ttataaaata
    11101 acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt tcgaatggtg
    11161 ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg attcttgcaa
    11221 actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta tgttttaaat
    11281 aaacttgctc agaggagatg aattgtgtat caatgtagta atcgttatcc aacagagaaa
    11341 attctaaagg cttaatatta ccaccacgta taattctaac acctttatta ttaatgctta
    11401 aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt atttttataa
    11461 caacccaatt cataggtata ttcccataat aagagccata atcacaaaaa tagcaggtag
    11521 tcagtttgac cacctgttat tttttaccaa ttaacaattt tatctacaat attttgttgt
    11581 tcagtagctg ttttccttag ataaattcga gtagtttcta tactttcgtg tcccatcaaa
    11641 tctgcaagca aggcaatatc attatacttc gctaaaaaat tcttagcaaa taaatgccta
    11701 aaagaatgag ggtaaattac tttaggattc attttgtatt tatcagcata attttttaac
    11761 tgttgagcaa ctcctcttgc tgtaattggt tcgttaaatt tattcaaaaa taaataacca
    11821 cttcggcgat tttctgattc taaccaacta agacaactat ttcttaattt tttaggaatg
    11881 tacagtctac gaattttacc accttttgag taaatgtcaa aataaccgat ttctacatgc
    11941 tctactttta gtttaataag ttcacttaca cgagccccag ttgcacctaa aaaccaaacg
    12001 acaaaatgcc attttaaaat accatctttt ttcaaactac gtttaagaaa aaggtaatca
    12061 gcatggctaa tgacatcttc taaaaacggt ttttgctgta ctttgacaaa ttttaatttc
    12121 aaatcatcat gaccaataaa agccagatat ttatttactc cttgtagtcg caaattgaca
    12181 gttttaggtt taaaattgtc taataaatat cctttgtatt caaataaatc ttccattttg
    12241 agttcgtaat tctccaagaa aaatcgaaca ccataaaggt acgaacgcac agtattttca
    12301 gctaaaccag ctttcttcaa atgtaattca aaatctttca acgtaaaact cctatcttat
    12361 gtttgataga aattccaccg cacgtaaaac tattatacta aattagtgcg tcaatatggg
    12421 cgaaaaattg ttcgatttta tcaacgattc tggattgttc aggaaggggt gggaggggga
    12481 ttaaatattc ttttatagtt ttcgttaata attctttttg ttttgtacta cccgacgctt
    12541 tttcttcaat aactgactga acaataggag aggaaagaaa attatagatg aaatggcaat
    12601 taataacccc cgataagact cttataactg taacatggct atctgcaaca gcccagccat
    12661 aaggattttt attttcatgg taaatagcta atcgtcctaa cgtacctaga cctgttgaat
    12721 tccacattaa atcaccatct cttagtaatc tttctttctg gtaactatga actgttttgg
    12781 gatcaataaa tcttgctaag tcaatagaaa agccagacca ttgattacat ttctgagcaa
    12841 tcacagggta tataggaata tttgaatatt ttggagactt ccctctttga atgtaggagg
    12901 ttatatcgtt taacctcacc cattcccaac tttctggtat ttcacaaggt acttcc
//
LOCUS       DAVLBN010000055        12395 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLBN010000055 DAVLBN010000000
VERSION     DAVLBN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.055"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            122..277
                     /locus_tag="VXC24_001669"
                     /pseudo
     CDS             122..277
                     /locus_tag="VXC24_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            477..3752
                     /gene="rexB"
                     /locus_tag="VXC24_001670"
     CDS             477..3752
                     /gene="rexB"
                     /locus_tag="VXC24_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0493755.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3749..7399
                     /gene="addA"
                     /locus_tag="VXC24_001671"
     CDS             3749..7399
                     /gene="addA"
                     /locus_tag="VXC24_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0493756.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7614..8792
                     /locus_tag="VXC24_001672"
     CDS             7614..8792
                     /locus_tag="VXC24_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493757.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8994..>12395
                     /locus_tag="VXC24_001673"
     CDS             8994..>12395
                     /locus_tag="VXC24_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0493758.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPAVQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAP
                     LPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKP
                     ENGASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDS
                     SLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYY
                     LPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGK
                     LIGKNNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLID
                     NVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTAGYEIGGLVGKLSGSL
                     ASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVA
                     GNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAGYNFNGIKTIETYSNKNNKVVNVVQ
                     EDDEVVTKDSDVQRGTVLDADKVKEKKVELVSKHSTKVEDFDFTSRYNTNYNEVTGYQ
                     QSREQVYKNIEKLLPFYNRETIVKYGNLVEDNSDLFTKKLLSVVPMKNNEVITDINKN
                     KQEINKLLLHFEGNKSRVLNIAYKNDFSKVAEYDIANTKLMYTPNT"
BASE COUNT         4108 a         2364 c         2572 g         3351 t
ORIGIN      
        1 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
       61 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      121 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      181 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagatac tgggacaaca
      241 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      301 cttttttatt atgtgatttt cagtagccag acttattcta tctaatacaa gtaaagctaa
      361 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      421 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      481 aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga gaggcagaag
      541 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      601 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      661 gctttgctca aatggctcgt tatctggtct tgaatgattt accagctaaa actactcttg
      721 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      781 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      841 accatgagat gaccaaatct cagatgaatt ttttggactt ggagaattta acagatgagg
      901 ataagagggc ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaagggc
      961 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1021 gtagtgattt taatcaaatc gccttggtca ttgacggctt tactcgtttt tctgctgagg
     1081 aagagcgggt tgtggactta cttcacggca aaggtgctga gattgttatc ggggcttatg
     1141 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctctaccaa gccagcgtaa
     1201 aatttctcca tcatctggct tctaaatacc aaacgcccgc tcaggactgt tctcaaactc
     1261 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1321 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1381 tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa ttacatgaga
     1441 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1501 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1561 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1621 gttttcgtca ggaggatttg attaatcttc ttagaactga cttgtatatt gacctcagtc
     1681 agtctgatat tgatgctttt gaacaatata tccgctatct tggtattaat ggcttgccag
     1741 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1801 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1861 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     1921 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     1981 aggctttttg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2041 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2101 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2161 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2221 gtcttctgac agatgaagaa aggaaaaacc taaaccaaac gaccgaagaa ggcgttcaat
     2281 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2341 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2401 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2461 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2521 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2581 aggttctgtc gcgtgtcata ggtaaaaaac tagatcagca aggtctggaa aatccagcta
     2641 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2701 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2761 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcat cctgatgccc
     2821 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttacagttg cctaatgaag
     2881 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     2941 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3001 cacggacgac tggacatatt ctccgacaca atccagccat cgaaaccatc aaagaagaag
     3061 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3121 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3181 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3241 agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt ttcggcgcca
     3301 tgtacttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3361 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3421 gttatttagg cgaattttat aacaaaaaca aggctaatca actgacagat gaggaatttc
     3481 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3541 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3601 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctag
     3661 aaaagttgga cctagctgat ggcaagcgtc tggtcggaga aaaactcaag caagcttggt
     3721 ttgaaaaaat aagagaggag ttaaatcgat gaagcttatt ccctttttaa gtgaggagga
     3781 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3841 acaaatcgaa gctatctaca cttctggtca gaatatcctg gtctcagcat cggctggttc
     3901 tggaaagacc tttgtcatgg tagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     3961 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4021 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgatctca aacaacactt
     4081 gggttgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4141 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4201 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4261 ttaccaaggt aaacagaaag agagctttag tcatttgctg aaaaactttg ctgggcgtgg
     4321 caaggacgaa cggggtctgc gccagcaagt ctataaaatc tatgacttcc tccaatccac
     4381 cagtaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4441 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctctggg atttggaaag
     4501 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4561 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagttcg atagtcaggc
     4621 ttatcaggca gtacttgcgc gtgttgtcgc catctctaag gagaaaaacg gtcgtgctct
     4681 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4741 aaagacccag tttactaaac taggacaatt atcagaccag atagcgattc tcgactatca
     4801 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4861 ttttgtagag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     4921 cagccattac accattgaga ttttagaaaa tttcccacaa gttcgtgagt cttatcagga
     4981 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5041 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5101 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5161 aaatcctcaa gaaggcaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5221 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5281 ctatgataac atgcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5341 caaggctgaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5401 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagattctga aacttcatca
     5461 agaaaaaggt gttgccttta aggaaattgc ccttctgacc tccagccgca gtcgtaatga
     5521 ccagattctc ctcgccctgt ctgagtacgg gattcctgtc aaaactgacg gagagcaaaa
     5581 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5641 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttt gttttgatga
     5701 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5761 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5821 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     5881 accccactct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     5941 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6001 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6061 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6121 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6181 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6241 gaatggtctt ggtgtcaaat atattgccaa gatggagaca ggggcagtag aagaccacta
     6301 tcctaaaacc atcaaactct ccattcctag tctgacctat aggcagaacg aagaggaatt
     6361 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6421 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaatcca aggaataccc
     6481 agcagccaaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6541 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6601 tattggcgaa gatcagttga ccagagaagc tatcggagag ttggaaacca agagtcctct
     6661 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6721 gctgaaggag gtggaagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6781 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6841 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     6901 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     6961 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacacgttca
     7021 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7081 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7141 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7201 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7261 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7321 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7381 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7441 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7501 ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgttttgag ctgactgcgg
     7561 ctagctttct agtttgctct ttgattttta ttgagtatta gaaaggagac ctcatgacac
     7621 ttccagttag aaaatccctg cacgatgcag ttttacaggc ttcgaaagcg gatacttggg
     7681 aacaagctac caaggaatgg aatgaagttt ccttgatttt taacggtatc ggccgtagca
     7741 tttgtgtctg tggaaatgtc atcaaatacg cttatgaact ctttaacggt gtcacaggcc
     7801 aacgcctctt tccaattggt agcgactgtg ttcgtcattt tcatcgattg tcccttgacc
     7861 agcaattgga agaggaagaa aaactgctca gaaaggttga aaatctaacc agaaaagctc
     7921 agaaaaagga aaaaatcaag gtcaataaaa gtgactttga cgagcgactt ctaaaatggc
     7981 tctgggaaaa aggtgttttc aaacccaatc gtggcaatca atttgcgcct gagagagact
     8041 accagctttt cctagaagtc tttcagggag gaagttggac caaggcggaa ccaaagaaaa
     8101 aggctcggat ggaagaagtc cttgaaaagt gtatcaaacc ctttttactt gggaaatcgg
     8161 atgaccaact ctaccttgtc aagctaggca aggagaaaat tgactacgaa caagaactcc
     8221 gtatccaggc agagaaagaa cgcaagaaga gggataaaat cgccaagcaa tatgcagaca
     8281 atctggttct agccatggga cccgcagagc gtgcttatca agattacttt ggctttacag
     8341 agaccctgac tcaagaagaa cgcaagtggg aaaaaattct ttttggtaaa aatagagcag
     8401 aacgggctat taaggccaaa caataccaaa aagagctgga aaaagaccaa cgaattgcca
     8461 gtcaggatcc aattgaaaga aaacagaaac agacttggct cctcaattcc tattttcgtg
     8521 agcttcctga agaaaaagct cgattttcta ggctcttatt agaatatcga aaaaatggtg
     8581 aagtaccctt ttcaactgaa tacctgtcag atcatctcat cgactttttc tataaaatga
     8641 aagcctttga atttgaaatc gcaccagaac aagtccgaga ttttctaaaa aaaagcctgc
     8701 aggaagacta tcgctcatca gcacaaggaa gctggataga aggaattctc ctcaactgcc
     8761 tcaaaccatt tttagaacga ttagtgatat gagtaacacc taccgtgtaa atttcatggt
     8821 aggtgttatt gtacccccaa ataatataaa acaaagtatg aaagcgcatc tcaattttaa
     8881 gacttttttg taaattaaga gtataattaa ggtatactgc cttttctata gataatacac
     8941 taatataata aaggtctttg taacatatat aaattttatt tcaaggagga ataatggaaa
     9001 agtattttgg tgaaaaacaa gagcgttttt catttagaaa attatcagta ggacttgtat
     9061 ctgcaacgat ttcaagttta ttttttatgt ctgtattagc tagttcatct gtggatgctc
     9121 aagaaactgc gggagttcac tataaatatg tggcagattc agagctatca tcagaagaaa
     9181 agaagcagct tgtctatgat attccgacat acgtggagaa tgatgatgaa acttattatc
     9241 ttgtttataa gttaaattct caaaatcaac tggcggaatt accaaatact ggaagcaaga
     9301 atgagaggca agccctagtt gctggtgcta gcttagctgc tctgggaatt ttaatttttg
     9361 ctgtttccaa gaaaaaggtt aagaataaaa cggtattaca tttagtattg gttgcgggaa
     9421 taggaaatgg tgtcttagtt tcagtccatg ctttagaaaa tcatcttttg ctaaattaca
     9481 atacggacta tgaattgacc tctggagaaa aattacctct tcctaaagag atttcaggtt
     9541 acacttatat tggatatatc aaagagggaa aaacgacttc tgattttgaa gtaagtaatc
     9601 aagaaaaatc agcagccact cctacaaaac aacaaaaggt ggattataat gttacaccaa
     9661 attttgtaga ccatccatca acagtacaag ctattcagga acaaacacct gtttcttcaa
     9721 ctaagccgac agaagttcaa gtagttgaaa aacctttctc tactgaatta atcaatccaa
     9781 gaaaagaaga gaaacaatct tcagattctc aagaacaatt agccgaacat aagaatctag
     9841 aaacgaagaa agaggagaag atttctccaa aagaaaagac tggggtaaat acattaaatc
     9901 cacaggatga agttttatca ggtcaattga acaaacctga actcttatat cgtgaggaaa
     9961 ctatagagat aaaaatagat tttcaagaag aaattcaaga aaatcctgat ttagttgaag
    10021 gaattgtaag agtaaaacaa gaaggtaaat taggtaagaa agttgaaatc gtcagaatat
    10081 tctctgtaaa caaggaagaa gtttcgcgag aaattgtttc aacttcaacg actgcgccta
    10141 ttccaagaat agtcgaaaaa ggtactaaaa aaactcaagt tataaaggaa caacctgaga
    10201 ctggtgtaga acataaggac gtacagtctg gagctattgt tgaacccgca attcagcctg
    10261 agttgcccga agctgtagta agtgacaaag gcgtaccaga agttcaacca gcgttgtcca
    10321 aagcagttat aaccgacaaa ggtgagactg aggttcaacc agagtcgcca gatactgtgg
    10381 taagtgataa aggtgaacca gcagtccaac cagagctacc ggaagcggtt gtgactgaca
    10441 aaggtgagac tgaggttcaa ccagagtcgc cagatactgt ggtaagtgat aaaggtgaac
    10501 ctaaacaggt agcaccgctt ccagaatata caggaccaca agccagcgct attgttgaac
    10561 cagagcaggt agcaccacta ccagaataca caggggtaca agccggatcg atagtcgagc
    10621 cagagaaagt agaagcaccg aaagaatata ctggtaaaat cgaacagcct agtgcagaag
    10681 atactaaacc tgaaaatggg gcaagctcta caaatgggga atcggaacgt cctaaagata
    10741 aaattaaaga agaaaaacaa gtcgacaaga aactagaact tagaaatgtt tcaaacgtgg
    10801 aattatatac ggtagaaaat aataaatatc gacatattac ggctgtagat ggtgctttag
    10861 atagttcatt gaagtatttc atgaaggtaa aatcagaaaa ttttaaagat ataatgttgc
    10921 ctgttactaa aattgaaagt acaacaaaaa acaataaaga agtatacaaa attgtggctc
    10981 atgcagaaaa tctaattcaa cacgaaaaca atgttatttc gaatgactat acatattatt
    11041 taccaaaaac tcagcaaagt gaaactggcg tctatacatc atttaaaaat ttagttgatg
    11101 caatgaatag tgaccctaat ggaacattcc atttaggtgc aactatggat gctcgtgaag
    11161 ttgaacttcc ggatgatcaa gaaagttatg taaaaaatga attttacgga aaattaatag
    11221 gtaaaaataa tggtaagtat tatgctattt ataacttgaa aaaaccttta tttaaaactc
    11281 taaacaccgc tactattcag aatctttcaa taaaagaagc gaatgtttct tctaaagaag
    11341 atgctgctac aatatcgaaa gaagcaaaat acaatactct tatagataat gttcattctg
    11401 atggtattat agctggtgaa cgtggaattg gtggattggt ttcaaaagta gataactcga
    11461 gaatttctaa tagtagtttt acaggcagaa taactaacac atatgataca actgcagggt
    11521 atgaaattgg tggtttagta ggtaaacttt ctggttcgct tgcttctata gagaaatcaa
    11581 tagcatcgat tgacatagcc tctaatgcaa aatcaggaga tcaaattgtt ggtggtatag
    11641 ccggagttgt tgagaaaagt gcgacaatta agtatagcta tgttgaagga aatgttaaca
    11701 atgtgcgaca ctttggtaaa gttgggggag ttgcaggtaa tctttgggat agagattcac
    11761 aagatgtaag taaatcaggt aaactatcat atgttttaag tgatgtcaat gttacgaatg
    11821 gtaatgctat agctggctat aatttcaatg gaataaaaac gattgaaaca tatagcaata
    11881 aaaataataa ggtagtaaac gtagtacaag aagatgatga ggttgtgact aaagattcag
    11941 atgtacaaag aggtacggta ttagatgctg ataaagtaaa agagaaaaag gtagaattgg
    12001 tttctaaaca cagcactaaa gtagaagatt ttgattttac ttcaagatac aatactaatt
    12061 acaatgaagt aacaggttac caacagtcga gagaacaagt atataaaaat attgaaaaat
    12121 tacttccttt ctataacaga gaaacaatag ttaagtatgg taatttagta gaggataaca
    12181 gtgacttatt tactaaaaaa cttctatcag ttgttcctat gaagaacaat gaagtaataa
    12241 ctgatattaa taaaaataaa caagaaataa acaaattgtt attacatttt gaaggtaaca
    12301 aatcacgagt attaaatatt gcatataaga atgatttctc taaagttgct gagtatgata
    12361 tagctaatac aaaattaatg tatacaccta ataca
//
LOCUS       DAVLBN010000056        12387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLBN010000056 DAVLBN010000000
VERSION     DAVLBN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.056"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(344..544)
                     /locus_tag="VXC24_001674"
     CDS             complement(344..544)
                     /locus_tag="VXC24_001674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493759.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(576..791)
                     /locus_tag="VXC24_001675"
     CDS             complement(576..791)
                     /locus_tag="VXC24_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493760.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            complement(810..974)
                     /locus_tag="VXC24_001676"
     CDS             complement(810..974)
                     /locus_tag="VXC24_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493761.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            1181..1870
                     /locus_tag="VXC24_001677"
     CDS             1181..1870
                     /locus_tag="VXC24_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0493762.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            2114..2905
                     /locus_tag="VXC24_001678"
     CDS             2114..2905
                     /locus_tag="VXC24_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0493763.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            3054..4004
                     /locus_tag="VXC24_001679"
     CDS             3054..4004
                     /locus_tag="VXC24_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV0493764.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            4283..5410
                     /locus_tag="VXC24_001680"
     CDS             4283..5410
                     /locus_tag="VXC24_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0493765.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(5498..6409)
                     /gene="whiA"
                     /locus_tag="VXC24_001681"
     CDS             complement(5498..6409)
                     /gene="whiA"
                     /locus_tag="VXC24_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0493766.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(6406..7383)
                     /locus_tag="VXC24_001682"
     CDS             complement(6406..7383)
                     /locus_tag="VXC24_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0493767.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(7380..8270)
                     /gene="rapZ"
                     /locus_tag="VXC24_001683"
     CDS             complement(7380..8270)
                     /gene="rapZ"
                     /locus_tag="VXC24_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0493768.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(8322..8702)
                     /locus_tag="VXC24_001684"
     CDS             complement(8322..8702)
                     /locus_tag="VXC24_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0493769.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(8713..9300)
                     /locus_tag="VXC24_001685"
     CDS             complement(8713..9300)
                     /locus_tag="VXC24_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0493770.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(9309..10541)
                     /gene="clpX"
                     /locus_tag="VXC24_001686"
     CDS             complement(9309..10541)
                     /gene="clpX"
                     /locus_tag="VXC24_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0493771.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(10573..10743)
                     /locus_tag="VXC24_001687"
     CDS             complement(10573..10743)
                     /locus_tag="VXC24_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493772.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(10743..11249)
                     /locus_tag="VXC24_001688"
     CDS             complement(10743..11249)
                     /locus_tag="VXC24_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0493773.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(11379..11897)
                     /locus_tag="VXC24_001689"
     CDS             complement(11379..11897)
                     /locus_tag="VXC24_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0493774.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
BASE COUNT         3865 a         2627 c         2214 g         3681 t
ORIGIN      
        1 ctcaagaaaa ctagtgtttc ttaaaagttt ttcaactaac tcagggtctg cctttacaaa
       61 ggtggactct tttttcccac tatacggata tcgtcttggt ctcatttcct cacctccttt
      121 gtatttattt tttctaccct ctcttttatt tagagaagta ggactggttg tcttttaata
      181 cttgttgtta gttaatattt attagtgtaa aaaatttgac atgaaaaagt ttgacatgaa
      241 aaaaacttac atctcaaaaa tttaatcact aatcgcttta tcgagtcgct gtaacatgat
      301 atcaaactgg aaatcaaaac aggtttcttt cgtcatcttg aaatcatgaa tgctgattcg
      361 tggtttgttg aacttgctcg ctcaatttat caagattttg agaaatcaat ttcagattct
      421 cactaatcga gcgtgacttt ttttgatacg gcaatctcag aaatttacca ccagaggtaa
      481 ctaccttaat gattttttcg aggtggtctt tttcttgttt caagctttca agaacgcttt
      541 ccatctatgt gttcctcctt cttatttttt tgtttctagt tatttacgaa attttcgtat
      601 tttttcccta aaaaaatatc atcgaatttc acattgaaaa aaaacatgta ttttttcaat
      661 agctgataac cgatatcaga gctatctttt tctaatctag caattgtttg acttgaaact
      721 tcaaattttt ctgccaactc tgcttgagta agtcctttgt tgattctcat agcttctaaa
      781 gtccactgca cgttcctacc tcctttctgt taaagtagtt ctacttcttt ttttgcgtct
      841 tctatagaaa ttagggttgg gttatcgaac caatcttttt ctaaataata ctttttctca
      901 tgctcagaca tataagcaat caatgactga aaatgcttta tgcgttcatg aagatgttct
      961 atattttctt tcatccatcc tcctactcct taaatttttc caaatatatt tttcgcttgt
     1021 atatttccaa catcaatctt attgatattc aacattaact cagggtctgc ctttacgaag
     1081 gtggactctt ttttcccact atacggatat cgtcttggtc tcatttcctc accccctttc
     1141 aaatatggta taatcaaaat aaaacgattg gagaaatctt atgatatttc gagtgaaagt
     1201 aaattcttct gtttctaggc ctgtaaccgt tgaagacatt tgcccaaatt gtaaaaaacc
     1261 aaccaatcca gatcttgtga actcttctta tttttctctt ggagaaaata aaacaagctt
     1321 agtattaaca tgtagatgct taggttgtaa gcacttttgg acagaggagt ttatagctac
     1381 aagattttta atcaatgact ataccgaaaa atacgaaatt gaacatatca aagtaatccc
     1441 taatcttccg agcgatatac ctatatctga cgatgtagag atagtttctc caattggtaa
     1501 gcaaatctat gtccaagcac tgaaagctga acacgaacaa ctagaccaca ttgcaggtat
     1561 tggataccgt aaggcgcttg agttctttgt taaagatttc tccattgtta caaatcctga
     1621 tgatgaagat aaaatcatta aaatgtcatt aaaacaagtt attgaaaaat atatcaagga
     1681 tgaagacctt aaaacatttg cgcttgcatc tgcttatatc ggtaacgacg aaggtcatta
     1741 ctatagaaat aatcctgata aaggttttac agacctaaag aactacctac acggagttat
     1801 tcactacatg gaaatgaaac tcaatttcct tgatgctcaa gagcttgtga atcgttcaaa
     1861 gaaatcttag aatctacttc atccaacttc tcagctatat atgtcacagt cctcaatatc
     1921 tcattgaggg ctgttctttc tagttcgttc atttgcctta cctccttttc cttaagcttg
     1981 atttaattat aatacgattt tttcgtattg tcaatagttt ttatcaaaaa aataggattt
     2041 tttcgtattt ttgattgttt atcattcaaa aatgatatat aatgtaatta taaaaaatac
     2101 gaggtaatcg taaatggacg aaaaaaaacg aatgcaaatt attgctgaaa atattacaca
     2161 ctttagaaag caacgtggca tcacccaaaa agagttggct aaagaagttg gaattacagc
     2221 aagtactatg acagactata tgaagttaag aagcgctcct tcttttggtg ttatccaaaa
     2281 actggctgat tatttcggtg ttaaaaaatc agatatagat actactttta aagaagaatc
     2341 caccaactca ctgccagacg ctccagattc gctcacacag cagataatgg ataaggtagt
     2401 gcaattaacc ccacccaatc aaaaaatcgt gctacggacc tctgaggagc ttctggagag
     2461 ccaaaacgaa gaagaaacga agataaacga agtatcggaa gttatcagct tgtaccaagt
     2521 tgaggttgta tctgagacgg cagcagcttc tggatttaac tatggatttg ggtacgacga
     2581 tacagacaga gagactatag aggttgacga gcgaccacca cgccacgata ttgcgaccaa
     2641 ggtcagtgga gactccatgc aacccgacta ccaagacgga gacattctct atttagtaga
     2701 caaaggactg actacctaca acggagattt agcaattatc gcatatggag accgttctta
     2761 cttcaagaag atatataccg aaaacggacg cttacgccta gtgtcactca atgacaagta
     2821 cgaagacatc atcctagact tcccaccagc cgaagacaca cacatcaaga tttatgcagt
     2881 agtcggggtg tatagagggg aataaaaaaa ttatttttta aaaatattaa aaaacagttg
     2941 acttttttaa aaaaatcatt tagaatgaat tcattagaga aaaagcgtcg ggatctctac
     3001 ggggaccgat acggggaaac tccttcattc taaattagaa tgggggagtt tttttgaagc
     3061 catttaaaac aatcgaggaa caaatcgcaa cactaaaaat cagagggtta tccattacag
     3121 atgaatctaa agcagctaag tacctgctaa gtaacaatta ctacaatatt atcaatggat
     3181 acagtaagtt ttttcaacac cctggtactg acacttatat tgacggcgtc acatttgacg
     3241 aagtttcaag tctctataca tttgacaaag atgtaaaacg agccattttg caagctattc
     3301 ttgaagctga acaccatatc aagtcaatca ctgctcacag attcgccgaa gcttacccca
     3361 gtcaaaaata cgcttattta aacaccaatt cttatgcaga taataaaata ttagacgtgg
     3421 gatttattgt atcaaaacta tccaaaatca taaacacaaa caagcgatac agaggaaatt
     3481 caattcacca ctacgcacat actcattcag atgtcccaat ctgggtacta actgattatc
     3541 tagagtttgg agatttacgc acgattattg aaaacctgcc taattcactc caaaatgaaa
     3601 tcgcacggga tttagtaagt tttataagca caaacatacc tgactttaac gatgttttcc
     3661 caccagaaac cttgatatct tttctaaaaa atattaacga ggtacgaaac aaatgcgctc
     3721 acaataatcg cttattaaac ttcagatgcc gttctaatag tacgttttgg gaaacgattc
     3781 ataacaaaga gatcttgatg ggagatgaca gtagaaaaac tgtatattca acaattatta
     3841 gccttcaatg ctttattagt aaagcagcat tcaacatttt gtggaatact cttagaaaaa
     3901 aagttatcaa actagagaaa aagctgcctt ctatagacat caatgtaatc aaccagtctt
     3961 taggttttcc taatgattgg caccgtaatg aaccaaaagt ataaattaaa accaactatt
     4021 tccatttagg aaataactgc ttgacagaaa ttaaaaaaag aaatacacta agaatgtaaa
     4081 aaagccttgt tcgtcaagga taaaatcgtc tggtgtactt ctaagaggta caccttattt
     4141 tattatctga cgagatagca accaaaaaat ccccacactc aaattttggc caaggagagt
     4201 gtgaggaaat catgtatagg aaacaaccat taaaaaggta gttttcttgt acccatttta
     4261 acaaaaaagt gaggtaaacg caatgtggat ggaagaattg ccaaatggca aatttaaata
     4321 ttttgagcga tataaagatc catatactga gaaattaaaa aaagtttcag taaccatgga
     4381 gaagaaaact ccccaggcaa gaaatcaagc tgctatcttg ttacaagaga agataaataa
     4441 aaaactcagc acaaaacaag tagaaagcat tacatttgaa gaaatctata accttttcta
     4501 taaatcatgg gcgcaaacag taaaggaatc aacaaaacat aattgtaaat cagttgataa
     4561 gaagatgaag gaagtcatac catccgatac catacttgct aatcttgaca ggcgttttct
     4621 tcaagaggct attgaaaaaa ttattgaaag caacggatat attacagcta aaaaagtacg
     4681 gcataggctc agaggtatct ttaattacgc tgttcaatac tcttacattg aaaacaacga
     4741 ggtcgattat actacgattc ctcaaaaacc aaagacttta gaagaactgg aaaaaaagcg
     4801 taacaacttt ctcaccatgc aagaaataaa agcacttgtc gatgtcctta atcgtcgaga
     4861 atatcaccaa aagtacgctg atatggttct tgtgctgaca ttaactggta tgagatatgg
     4921 tgagttaact gccttacaac tgaagaatat agacttcgaa aacaacaaaa ttgagatcac
     4981 aggtaatttt gattcagtaa acaaaatcaa gacgctacca aagactacaa attcaatacg
     5041 gacaatcaaa gtatcagaga gtgtcataga agctattcaa agacaaatag tacgacttag
     5101 cgaacgtttc cagccattgt caagcgatga ttatattttc tgttttgaaa aatggaatca
     5161 acctacaaca atagcttgct tcatacagat attaaaaaaa tatggaaaac aggccaaaat
     5221 agaaaaaaac ttatctagcc atatttttag gcattctcat atttcgtttt tagcagagtc
     5281 tgacctccca ataaaatcaa taatggatcg agttgggcac tcaaatgcaa aaatgacttt
     5341 ggaaatctat tctcatacta ctgaggatat ggaggataaa ctggtcaata aattagatac
     5401 tattttttaa ttctgcccct tgattgcccc tttttgattt cataacacaa caaaacccct
     5461 tgaagatatt gataattcaa ggggttgctt tatatcgtta taattcatcc gctatcttat
     5521 tgatttttct gagtctgtga ttgacaccac ttttggtcag aggggtgctg agactatctg
     5581 ctaactgctg gatagagtag tctgggtgct gaatcctcag ttgcgccact tcctgcaaat
     5641 ctactggcaa attttctaag cccatgatat ctttgatttt actgatattg ttaatggtct
     5701 tcatgctggc agaaactgtc cgagcgatat tagctgtctc ggcattatta gcccgattga
     5761 ggtcgttacg ggtttctcgc aaaatcttaa cccgctcaaa atcatcacgt gcctgcatgg
     5821 ctcctattac tatcaagaag tccataatgt cttctgctcg ctggagatag gtcacagccc
     5881 ccttcttgcg ctcaagcacc ttggcatcca gtaaaaactg ttggagaagg gaggcaattc
     5941 cttgcgcgtg gtccagataa acagaactga tttccaactg gtacttgcct gactcagggt
     6001 cacgaatgct cccatttgcc aagaaagcgc cacagagata ggcacgacct gcttcctcat
     6061 ccgataaaat cgcctcatca atacctgttt ccaggccaaa gaaagagtct gccaagtgca
     6121 aatcacttaa caaatcctgc accttttcat ctgtaaaaac ggtatagacg cgattcttgc
     6181 gaagattgct ccgttggtgg tgacgaattt cagatttgat ttcatagaaa tggagaaagg
     6241 actcatagag gtgacgggcc agtttggcat tttctgtcac aactgacaaa gtcaagcccg
     6301 aagtcgagag accgatgcta ccagacattt tgataatggc agataattca tgccagctca
     6361 gatggtgttg gcccaggatt tcttctttta ctgctactgt gaaactcatt ttttcacctg
     6421 tataatgcgc atcaactcgt ccacaatcaa atctccatcg tggaaggcac cgccattttc
     6481 cagacgaagg aagttagatg aaatcacgcg cgaaacttgc ttacaaagac ctacaaaatc
     6541 gtgttccact tgcaccaagt attcatcaaa acggttggaa ttcatgtatt cctgaggcac
     6601 tttttcaata ttcaccaaga cagtgtcgat aaaagggcga ccaaggtgac gatgcaagac
     6661 ttccacgtgg tcgctatctg taaagtgttc cgtctcccca cgttgggtca tgatattgca
     6721 gacataggca atttctgcct tagtttccaa aagagcccgc ccaatttcct taatcacgat
     6781 attgggcaaa atagaggtaa agagggaacc tggccctagg acaatcatgt cactttcaag
     6841 gatggtctgc actactcgac ggctggccag aggcgtatca tcgtttaggg cattggtcac
     6901 atagacattg tcaattatgc ctcgatggtc tacaatatga ctctctccag ccacttctgt
     6961 cccatcctga aagactgcat gaagggtcaa aggatggtca ctggaaggat aaattttccc
     7021 tgttgtatgg aaaaatttgc tcaataactg catggcatta taggttgaac cctgcatttc
     7081 tgacaagcca gcaatgatga gatttcccaa tggatggcca gcaaaggctc cggcatcctc
     7141 agagaaccga tactgaaaga ccttctcata aaacttaggc atatccgaca tggccacaag
     7201 gacattacga agatcacctg gcggtgtcaa ctgttgcata ttttttcgga gttcacctga
     7261 agaaccacca tcatctgcca ccgtcacgat agctgcgatt tccacatctt tttcccgcag
     7321 actttttaga atgacgggaa ttccagtccc tccaccaatc accgttatct ttggttttct
     7381 catgaacggt ttaccgtttc ctttctgcgg tctttgtcgc gatgcccttc attaacagac
     7441 caattcttgg ataagtcctg cgccaagcgt ttagcaaatg ccacactacg gtgttgtcca
     7501 cccgtacatc ccatggcaat ggtcaaaacg gacttacctt ccttttggta acttggcaga
     7561 atcggctcaa tcaaggccaa taaatgttga taaaagtctt ctgactcagg atggttcatg
     7621 acataatcat aaacaggttc atccacaccc gtttggtttc tcagttctgg tagataatag
     7681 ggatttggca agaaacggac atcaaagacc aagtccgcat caatcgggat tccatactta
     7741 aatccgaaag acatgacttc gatacggaaa gactgggctt gttcttggtc tgaaaactgc
     7801 tctgcaaggg ttttgcgcag ctcacgtgga gtgagttcag tcgtatccac cacattttgg
     7861 ctcatatttt tcaaaggtgc caagagttca cgttccaact tgattccatc taaaatacga
     7921 ccgtctgctg ctagtgggtg actccgtctg gtttccttgt aacgagcgac caattcctta
     7981 tcagccgcat ccaaaaagag gattttgaaa tccaaaccat cttgattttc caactcatcc
     8041 aaaacagctt gaatctctga aaagaaagaa cggctacgca tatccactac caaggccaac
     8101 ttaggattgt cttccttaat ttcaaccagc tgcaaaaact taggcaagag agctggcggc
     8161 atattatcaa tggtgaaata acctagatcc tcgaaggact gaatggctac agttttccct
     8221 gcgccactca tccctgtcac aatcaccaag tgaaattgtt tctttgtcat ctttttctcc
     8281 ttatatcaaa agaagtttgg caacaccaaa cttcaactag cttatccaat ctctgcgatg
     8341 acttcaattt cgacttttac atcacgagga agacgagcta cctccacagc tgaacgagct
     8401 gggaattcct ctttgaaggc cgtttggtaa acctcattaa aaggaacaaa gtcgttcata
     8461 tcgctcaaga agcaagttgt tttgacaaca tggtcaaagt ctgttcctgc ttctgccaaa
     8521 atagcaccga tgtttttcaa gacttgctct gtctgttctt ggatattctc tcctacaatt
     8581 tccccagttt caggggatag gggaacttga ccgctagcaa acaaaaggtt gccaacgatt
     8641 tttccttgaa catagggtcc gatagccttt ggggccttat ctgtatgaat tgtttttgcc
     8701 attttctttt cctcacaatt tttctaagat tgcatcccaa gcctcatcca tccctgcctt
     8761 gctgacagat gaaaagagga tgaaatcgtc actcgggtca aagtttaatt tctttttgat
     8821 tgctgattca tgcttgttcc atttaccacg aggaatcttg tccgccttgg tcgccacaat
     8881 gatgactgga atctcataat acttgagaaa ttcgtacatc tgcacatcat ctgctgacgg
     8941 gtcatgacga aggtcaacta gactgacaac cgcacggaga ttttcccgag tcgttaagta
     9001 ctcctcaatc atgcaccccc acttttcacg ttccttttta gaaacacgag catagccata
     9061 accaggcaca tccacaaagc gcatcttgtc atcaatgtta aaaaagttca ggagctgggt
     9121 tttaccaggt tttcctgatg tacgggcgag attcttacgg ttcaacatag tgttgataaa
     9181 gctggattta ccaacatttg aacgccctgc tagggcaatc tctggcagtt catcctgcgg
     9241 atagtgggac ttattagctg cactgagcaa gatttcagca ttgtgtgtat taagttccat
     9301 agtcacctct aggctgtttc taggatcggt ttatccgttc catcgacagt ttctttagtg
     9361 atgcgaacca atttcacatt ttcctgactc ggcacctcaa acataacatc tagcatggtt
     9421 tcttcgataa tggagcgaag tccacgcgcc cctgtcttcc gttcgattgc tttattagca
     9481 atctcttgaa gggcttcgtc gtcaaattcc aactcaacat catcataaga aagcaaagtt
     9541 tggtattgtt tcaccaaggc atttcttggc tctttcaaga tgcgaaccaa gtcatcaacg
     9601 gtcaattgct caagagccgc aaaaacaggc aagcgtccaa tcaactcagg gataatacca
     9661 aatttttgaa tgtcttcagc gatgatttct tgcatatatg agctgttttc gtcaatcgcc
     9721 ttattatttt gaccaaatcc gatgactttt tcacccagac gttgtttgac aatttcttca
     9781 ataccatcaa aagcaccacc cacgatgaag aggatatttt ttgtatccac ttgaatcatc
     9841 tcttgttgtg gatgtttgcg tccaccttga ggcggcacgc tagcaacagt tccctcgata
     9901 atcttgagaa gggcttgttg caccccttca ccagaaacat cacgtgtgat agacacattc
     9961 tcactcttct tggcaatctt gtcaatttca tccacataga taatgccacg ctctgcacgt
    10021 tcgatgttaa agtcagcaac ctgcaagagt ttgaggagga tattttccac gtcctcaccc
    10081 acataaccag cctccgtcag agctgtcgca tccgcaatag caaaaggcac attcaagctc
    10141 ttagccaagg tctgggcaag gaaagttttc cctgaaccag ttgggccaat catcaaaatg
    10201 tttgacttct gcaaatccac atcttctgac tcttcgcgtg tatcgtggaa attgatgcgt
    10261 ttgtagtggt tataaaccgc cactgccaag gcacgcttgg cacgatcttg accaattaca
    10321 tagtggttca agatatggag gagttcaatt ggttttggca cctcagacaa gtctgccaag
    10381 acttcctcaa ccaattcttc tcgaatgatt tcctgagcta actccacgca ttcattacaa
    10441 ataaaagcat tgttgccagc aattattttt tgtacttctt cttggttttt gccacaaaat
    10501 gagcaataaa ccatcatatc attttttcta tttgtagaca tgatttcctt ccattctata
    10561 ctgtcattct atctaaaata aggtcatgta aaaagcatga atactattga ccagattggt
    10621 aaaggcattt aaccaaagga ggatagaaag cccgtaacgc tttttacgaa aagcctgtgc
    10681 tcctgccaga aagcagatga aacacagaaa agccgtgaat agaccaaata aactccgttc
    10741 cattagactt cctttctctt gcggtattgg atggtaaaat cataaggatt cttctcatct
    10801 ttggcgtaaa atttgcttga aactgtctca aaaagagaca agtcaagctc ttcagggaaa
    10861 taggtatctc cttccacccg agcatgaatg tgagtgacaa tcacttcatc aaggtaaggt
    10921 tcaaaagcct gaaaaatttg cttcccaccg ataatgtaga gattcttttc ttgatcctga
    10981 taccagtcaa gaacagactg gacgtcctga aaagtagcaa ccccatctat cttttcttcc
    11041 ggattacgcg tcaaaatcag ggtttcccgt tttggaagca agcgacgccc catcccatca
    11101 aaggtcacac gccccatcaa gatagcatga ttcagagttg tttctttaaa gtgctgcaat
    11161 tctgctggca aatgccaagg cagacgattt tccttaccaa tcacaccctc ttcatcctgg
    11221 gcccaaatag ctacgatttt cttagtcatg cttccatcct tttcactgat agtactattt
    11281 tatcaaaaaa ctcaaaaaaa gactggtttg gaatagctta caaaatagaa aaaatctgta
    11341 agaaatttcc tacagattta tctatgtttc cttatttctt acaaaccagg tgcttgtcca
    11401 agttcggctg caagcatcca aattgtttta tctgtttcag ttttagcgcc tgcaaagata
    11461 ccgtttgtta catcgtcacc ttcttcatca gtgacatcca aacctttttg gaaaagttct
    11521 gacaagtaac ggtagataac aagaacacgt tccaagcttt cttcaacatt acggtattca
    11581 ccagcttctt cttcgatttc actattttga aggaactctg tcaatgtaga gaatgggctt
    11641 ccaccgagtg taatcaagcg ttcgctgatt tcatccaatt gaccgtcaag agcttccatg
    11701 tactcatcca tttttggatg ccatacaagg aaaccacgac catgcatata ccagtgcact
    11761 tggtgcaaag caacgtgagc tacatacaaa tcagcaacag cttggttcaa gacttccttt
    11821 gtttttgcca atgctactgg cgctgctttt gtcaatgatg ttacgtcttt tactgcttct
    11881 tttttcaatt ctaccatttt ctttacctca ttcattattt tttgtaacca cttcttaatg
    11941 attactacct tagtatacta ctaaggaaaa ccaatagcaa gacaaagaac ttatatgaga
    12001 aaagttgcaa tagactgata atttaagaat tctttagaag acaaaaaaga gggttggatg
    12061 cttatagtca atggaaatcc atcagcaaac taggaaacta aacccagctt gaccaaagca
    12121 caagttttga ggtcgcaggt agaactgacc aagctgatgt ggtttgaaga aattccccaa
    12181 tactataata gattgaaata agatgaaacc aagtcgatta ggaaaggtaa atgaatttct
    12241 aaaatgtttt accaatcaca aggtctttgt ctatattcaa tctactatat aagcttcatt
    12301 tccgagcaag atcttgaatt tactcgagga tgaactatca taaaacaaag aaaaagaggg
    12361 tgctactatc acatccctct ttcaaat
//
LOCUS       DAVLBN010000057        12045 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLBN010000057 DAVLBN010000000
VERSION     DAVLBN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.057"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="VXC24_001690"
     CDS             complement(140..1342)
                     /gene="rpsA"
                     /locus_tag="VXC24_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0493775.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1504..1575)
                     /locus_tag="VXC24_001691"
     tRNA            complement(1504..1575)
                     /locus_tag="VXC24_001691"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1541..1543),aa:Gln,seq:ttg)
     gene            complement(1585..1665)
                     /locus_tag="VXC24_001692"
     tRNA            complement(1585..1665)
                     /locus_tag="VXC24_001692"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1629..1631),aa:Tyr,seq:gta)
     gene            complement(1715..1945)
                     /locus_tag="VXC24_001693"
     CDS             complement(1715..1945)
                     /locus_tag="VXC24_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0493776.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="VXC24_001694"
     CDS             complement(2113..2757)
                     /gene="pcp"
                     /locus_tag="VXC24_001694"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0493777.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2772..3695)
                     /locus_tag="VXC24_001695"
     CDS             complement(2772..3695)
                     /locus_tag="VXC24_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0493778.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3692..4381)
                     /locus_tag="VXC24_001696"
     CDS             complement(3692..4381)
                     /locus_tag="VXC24_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0493779.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4446..5150)
                     /locus_tag="VXC24_001697"
     CDS             complement(4446..5150)
                     /locus_tag="VXC24_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0493780.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5206..6228)
                     /locus_tag="VXC24_001698"
     CDS             complement(5206..6228)
                     /locus_tag="VXC24_001698"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0493781.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6358..8829)
                     /gene="parC"
                     /locus_tag="VXC24_001699"
     CDS             complement(6358..8829)
                     /gene="parC"
                     /locus_tag="VXC24_001699"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0493782.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9249..11192)
                     /gene="parE"
                     /locus_tag="VXC24_001700"
     CDS             complement(9249..11192)
                     /gene="parE"
                     /locus_tag="VXC24_001700"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0493783.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11328..11969
                     /gene="plsY"
                     /locus_tag="VXC24_001701"
     CDS             11328..11969
                     /gene="plsY"
                     /locus_tag="VXC24_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0493784.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3472 a         2734 c         2119 g         3720 t
ORIGIN      
        1 atcgctctga atatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttt
       61 ttcaacccac tacagttgac aaagagccag aaaaatcctt tgtttagtaa acaaaggatt
      121 ttgtgaattt tcaatttgat taaagttcga tatcaccaaa caaatcagcc attgaaaatc
      181 ctgtttgtgt ttctggaagt tcgaaatcac gcttttcttg acgtcttgga cgacgtggac
      241 gagcaacacg tttttcttct ttttgtcctt cttcttgggc tggacgttct tcaagagctt
      301 taatagaaag tgacacgcgt tctgcatctg cgttaacttc aagaacttta acttgaactt
      361 cttgaccaac tttaagagct tcttttggat tttcaatccg tttgtgtgaa atttgtgata
      421 cgtgaacaag tccatcgata cctggcaata cttcaacaaa tgcaccgaag tcagtcaaac
      481 gtttaactgt tccttctact acatcacctt tagccaattt ttgctcaacg ccatcccatg
      541 gtcctggtac tgttgcttta agtgaaagtg atacacgtcc ttcttcttcg ttaagatcaa
      601 ggattttcac ttcaatttct tcaccaacag ttacaactga ttttggtgat acattacgtt
      661 catgtgacaa ttcagtcaag tgaaccaatc cgtcaacacc accaagatcg acgaaagcgc
      721 cgaagcttgt gatacgagca actttaccag ttacaacatc accaacagcc aatttaccga
      781 atacttcagc gcgagctgct gcagtagctg cttcaacaac ttcacgacgt gaaaggatga
      841 agcggttttc tttagcgtta acttctttga ttttagtatc aaattcttga cctacaaaac
      901 gctcagcgtt acgtacgaaa cgagtatcca acattgaagc tgggataaat ccacgaacac
      961 cttcaaattc tactgaaagt ccacctttaa cggcacgcgt tcctttaaca gtaacaactt
     1021 cttcttcgcg accaacaagt ttgtcccatg ctttgcgagc ttcaaggcgt tttttagata
     1081 caaggtatgt aactgtatca gtatctttac caactacttg acgaagtaca agaacatcca
     1141 atacttctcc tactttaaca aagtcattga tatctgcatc acgatcgttt gtcaattcgc
     1201 gaagagtcaa gacaccttca acaccagttc cagagattgc aacgttagct tgagtcgcat
     1261 caactgtcaa tacttcagca ctaacaacat caccagtctc aacttgacta acgctattta
     1321 gcaaatcttc aaattcattc atctaaaaaa tcctccaaca atcaagtttt tcttaaactt
     1381 gacatactta taattttttt cctaagcacc cgcaaggaca tgttcatatc attcacgtct
     1441 ttcaattata aaaataaaat accctaagat attttgcttt ttatcttgat tattacctaa
     1501 gaactggggt agctggattc gaaccaacgc atgagggagt caaagtccct tgccttaccg
     1561 cttggctata ccccattaat gaaatggaga gagagggatt cgaacccccg aacccgaagg
     1621 agcggattta cagtccgccg cgtttagcct cttcgctatc tctcctacaa tcaacatgga
     1681 ctattatatc atgaaaattt caaaaaaaca agacttattt tgctaaatta taattttcaa
     1741 tcaaaatttc cacagctttt tccaattttt tataaaaact atcgacattc ccattcttta
     1801 taatggcaaa ttgtccgtct aattcggcaa tttctccgat aactttttta ccgatagtca
     1861 atgtataacc ttcaaaactg tctttaccaa cattaacttt ggcatccgct acttgaattt
     1921 cgattttttt atctttcttg ctcatttcat acctctcttc actttttcta ttttacaaga
     1981 aaatcctaaa actagcaaga aaaaactcta tatcaggctt ctctgatata gagttttatg
     2041 taaacaacct caatcgattt agcatagtta atagttagta aacaagcata attgactatc
     2101 ctttttaggt tatcagtgag tctcaccgcc tactaactgc aaatccttat ctttgtagtc
     2161 tacaatagct tcaatagcta cctctatgcc tcttacaata tcacatagac tcattcctgc
     2221 agtattcggc ttatttacta cttgttccat catatatgga atatgcatga aacctgctct
     2281 catattaggg aattttttat ccactaaata aagagcttgg tacatcaaat gattgcaaac
     2341 aaaggttcct gcactattgg atacaactgc cggaagtccc tgttttttga tagcttgtac
     2401 catcgctttg ataggtaaac tactaaaata ggccgatgct ccatcaatac gaatcggtgt
     2461 atcaattggt tgattgcctt cgttatcagg tatgcgagca tcatcttgat taatagccac
     2521 tcgttcaggt gttaagccgg tcctgccgcc tgcttgtcca atacaaagta cagcatctgg
     2581 ttgatatcgt aatatttctg cctctaaaac ttctgacgac ttataaaaaa ccgttggaat
     2641 ttctacccag cgaacttcag ccccattaat ctcagatggt aataatttta cagcctccaa
     2701 agctggatta atcttttcac ctccaaaagg attaaaacct gtaaccaata ttttcatttt
     2761 attttccttt actaaaatgc gagaaagtac attaagaata tgtgaataac aatcattact
     2821 agagcaacac ctgcttgagc ctttataacg ccattctgat ctttcatatc catcaatgct
     2881 gctggtagag cgttaaaatt agcagccatt ggggtcaata aggtcccaca ataacctgct
     2941 gtcatggcaa gagcaccagc cacaattgga ttagctccca gagcaaatac gaagggaact
     3001 ccaacacctg ctgtaataac ggtgaatgct gcaaaagcat ttcccataat cattgtgaat
     3061 agaaccattc caagaacata ggccaaaact cctataaagc gactatctga aggaacaata
     3121 ccgctaatca gatgagagat aacatcacca acacctgcta cagtaaaaat agcccccaaa
     3181 gcccctaata attgaggaac aatcccactt gttgaaactt gctgagtcat tcgattattt
     3241 tctgataaca gactcttagg gtgactattg gtaatcacaa gaacagaaat tgtagcaaac
     3301 aaggcggcaa ggctaatcga aatcttgcta aattctggaa tcatttgcgc taagaccaac
     3361 gcaagtattg ccatcagcat aactggaata aaaattttat ttttcaacct gttagattca
     3421 atattggctt tcatttcatc taaggatggc aaggttccga tacggacttg cttaaacaat
     3481 gttaacagcg ataataggat tacaataata ccaatactca tatttggcat ataggaacca
     3541 cctataaacg taatagacaa tagagtccaa aatgcagatg tcccaagtcg aactgggttt
     3601 gttttatctt tataactaca ataggctgta tggagaaatt gacaaccaat cacaatatag
     3661 gtcaactcta atagttgctt tgccaactct gtcatttttg ttctcctccc ctagtctttt
     3721 ttgatatcaa ttttttatca aataaataat tgtaaatccc cactacaata agtgttataa
     3781 cagcaacaat aatagatgta gaagcaatcc ctgcataatt gctttcatag cctaactgat
     3841 ctaatgttcc ccctatcaag aggactcccc cagcacctac aaacgtattt tgagcaaaga
     3901 aatttccaaa attttcattc gcagccgcac gcgcttttat tgtctcatct tcaacctctg
     3961 ttaactttct acctaattga gactctgcag ctgcttctcc cataggttga accaaaggtc
     4021 tgacaaactg agggtgtcct cctagacgaa ttgaaaagaa accagctaac tctcgaataa
     4081 agaaataaac tgtatagaag tttccaactg tcagaccttt aatctttcga atcaaatcga
     4141 ttgatcgttg cttgagtcca aaggtttctg acagccccac aagaggcaag gtaaccataa
     4201 aaatcgtgag cactcgctga ttgctaaatt cttttcccaa aatctccaaa aattcaacga
     4261 gagaaacacc tgaaactaaa gctgtaacca aaccagctaa gactactgtt gcaattgtat
     4321 caaattttaa aataaaaccc acaacaatga ttgctattcc tattaatcta atccactcca
     4381 tatcaaactc ctttatattc aaaatgacag tattttaaaa attttatcaa gatcaatacc
     4441 attccttatt taatgtgttt ttctagttct ttttggtatt tgctattgga ttccaatttt
     4501 tctttttgcc attttttaaa aacctcgtta tattcttttg ttgtaacaat atctttttgc
     4561 aatttcattc ctttaaagat atatggttcc cccttaatac caacttgtga gtatggtttt
     4621 gagaatggta ctacgttact tacaattgga gaaccaccag atgaagctgt tggcatcaat
     4681 aatgaactat ctgtcgacca agcttgagct ttggcatatt tttcatatct cttctctagg
     4741 tcagtggtct cagaaacagc atcttctaac aatttcttat atttatccaa accaggttta
     4801 gctacaacat ccttatcttt tcctttcgta ataccaaggt gtttcatggc agaaccagat
     4861 tttggatcca taatattcaa gtaagacgct ggatcttgat agcttggagc ccatcctgta
     4921 ctattcaaat catagtcttt ttgagaagga gcaacattgc cgtatttatc attttccatc
     4981 aaaccatcaa taacatttcc aataacgtct gtcgtcgatg ttcgagtcgt tatactgtag
     5041 cccaatgatg ctggatctac tgcatagaca taagaaaatg ttgtcggtgc atctgcttct
     5101 ttatcagttt ttccacaagc cactaaaata gctaacgtgc tcaggaccac tcctgctgtt
     5161 aagagccact ttttctattt cataaaaaat ctcctttggt ttattttaat ctacttttac
     5221 aatccaacct tctggcgctt caatatcgcc aaactgaata cccgtcaatt cattatataa
     5281 tttacgcgtc acaggaccta cttctgtttc actatagaat acatggaaat catcaccatg
     5341 ttgaatacct ccaattggag aaataaccgc tgctgtacca caggcacctg cctctacaaa
     5401 acggtcaaga ttatcaattg gaacatcacc ctcaatagga gttaatccca agcgatgttc
     5461 tgccaaataa agcaaggaat acttggtaat agatggcaag atagatggac tcaatggtgt
     5521 tacaaattca ttatcagctg taattccaaa gaaattagct gatccgactt cttcaatctt
     5581 tgtatgagtt gatgggtcca gatagataac atctgagaaa tggcgtgact tggccatttt
     5641 tcctggtaag agacttgcag catagtttcc accaacctta gccgcacctg taccatttgg
     5701 tgctgcacgg tcgtactcat cctgaatcaa gaagttggtt gggaccaaac cacctttaaa
     5761 gtaatttcca actggcatag caaagatggt gaaaatgtac tcttctgccg gttttacccc
     5821 gataatatct ccgacaccaa tcaaaagagg gcgaagatat aaggttccac ctattccgta
     5881 tggtggtacg tattcttcat tcgcacggac aactgcttta caagcttcta caaacatgtc
     5941 tgtcggaact tgtggcatca agagacggtc acatgtacgt tgcaggcgtt tagcattttc
     6001 atcaggacgg aacagttgaa cactgccatc cttagtacga taagctttca aaccttcaaa
     6061 tgcttgttgt ccatagtgaa gacttggaga agactctgaa atatgcaaag ttgcatcctc
     6121 tgtaagctct ccttgatccc attgtccatt tttgaaatga gcaagatagc gataaggtaa
     6181 tttcatatag gaaaaaccga ggttttccca atcaatcgtt actgtcatat tccactcctt
     6241 attctaaaaa cctatttctt atattctaca ctatttttct aaaatagcaa gtatattttg
     6301 taattttcag aaaattcctc caataaaaac catcttagaa ctgattcttc atttcactta
     6361 tttatcttca gtaactactt cctgaagata agcgtcaaaa acttcttcat ctgaaatcgt
     6421 gtcagaaatg aagcttccat tgctagtgcg ttctgacaag ttcaagtctt gcaatcggct
     6481 ttcatagatt gttcctttat tggattggac aagcagagtt tggtcgttca catccacttc
     6541 cgtactgaag aaatcgccaa caaatccttg ctctgcaact gctcctgcca agaagacacg
     6601 atgcggtttg tttttcaact cacgcaagac ttgtaatcct cgtttggcac ggctggttgc
     6661 tagaatttcc tcaatggaaa cacgtttcaa gcttccacgc tgggtcaaga ggtagaagga
     6721 cgaagtatta cagataaagc cagattggag gacatcatct tctttcaaat tcatagcctt
     6781 gacacctgct gccttagcac cgacaaccgg aacctcttcg atattgaaac gcagggcata
     6841 accattttga ctaaccaaga caacatcatc tagtttaatc ggagccactg ctacaatctg
     6901 atctgtatcg tctttgagct tagcatactt gacagactta gatctatagg tccgccatgg
     6961 agtgaattct tttcgctcta cccgtttgat ttgaccaagg cgagtcgctg caaagtaggt
     7021 tgtcgcatcg tcaaactgat ccagtacttc cacataaagg attgcttcat tcgtttcaaa
     7081 gtttgtgatg gtttggctca gatgctctcc gatgtccttc caacgaatat ctgccaactc
     7141 atggattggt ctgtagatga catttccaag acttgtgaac atcaagaggt gctgggttgt
     7201 cttggcagat tgaacaaaaa tcaaacggtc atcatcacgc ttgccaattt cttccaaggt
     7261 ggaagccgca aaggaacgtg gactggtacg cttgatgtaa cctgccttgg tcacgctgac
     7321 gtaggtatct tcctcagcga taagactagc tgtatcaatc tcaattgctt tcgcagtgtc
     7381 ttctaaagaa ctcaaacgag gagttgcaaa gttcttcttg acctcacgaa gttctttctt
     7441 catgagattg tacatagtcc tttcatcacc gataatagcc gccagcatag caatcttctc
     7501 acgaagctct gcttcttctt cctgcaagac aaccacatcg gtattggtca aacggtacag
     7561 ttgcaaagtt acgatagcct cagcctgttc ttccgtaaaa tcatagctaa ctttgaggtt
     7621 ttccttggcg tccgccttat tctcagaagc acggataaga gcaatgactt catccaaaat
     7681 cgaaatcaca cgaatcaaac cttcgacgat acggagacgt ttctcagcct tttctttgtc
     7741 aaagcgtgaa cgcgccaaaa tcacttctcg acggtgagcg atgtagctag acaggattgg
     7801 aacaatccca acctgacgag gtgtgaaatt gtcaatcgcc accatattaa agttgtagtt
     7861 gatttgtagg tcggtgtact taaataagta gttgagaaca agctcagtat tagcgtcttt
     7921 cttaagttca atagcgatac gaagaccatc acggtcagac tcatcacgaa cctcagcaat
     7981 cccagctacc ttgttattaa cacgaacatc atcgattttc ttgactagat tggccttatt
     8041 gatttcataa ggaatctcag taataacgat ttgttcctta ccacctttta gcttttcaat
     8101 ttcagtcttg gaacgaacaa ccacgcgccc tttcccagtc tcataggctt tcttgatttc
     8161 atcacgaccc tgaataatag cccctgtagg gaagtctggt ccaggtaaga attccatgag
     8221 tttatcaatc tttgcagttg ggtggtcaat catgtaaact gcagcatcta tgacctcagc
     8281 taaattatgg ggaggaatgt ctgtggcata accagccgaa atcccagtcg aaccattgac
     8341 caagaggttt ggaaaggctg ctggcaagac cgttggttct ttctccgtat cgtcaaagtt
     8401 ccatgcaaaa ggaactgtct ttttctcgat atcctgaaga aggtagcctg caatttcaga
     8461 caaacgtgcc tcagtataac gcatagccgc aggaggatct ccgtccatag aaccgttatt
     8521 accgtgcatt tcaactagaa tctcacgatt tttccagttc tgtgacatac gaaccatggc
     8581 atcatagata gaagaatccc cgtgtgggtg gaaattcccc atgatgttcc cgactgactt
     8641 ggccgactta cggtagctct tgtcaaaagt attgctatcc ttattcatag aataaagaat
     8701 acggcgttga accggcttca acccatcacg aatatctggc aaagcccggt cttgaataat
     8761 gtacttggag tagcgaccaa agcgctctcc catgatgtcc tccagggaca tgttttgaat
     8821 gttagacata agatacaaag cccataaaat accaagtgaa aatagaaaat tcttgaagta
     8881 agcaaactca caagagaatt tatctttttc acacagtatc tagggcgtgt tcaactcctt
     8941 tcaaagaatg tagagtaggt ttttatgcag taaaagatat tttacgggaa ttcgtcccgt
     9001 gttcagttac gataagtaac caaactatcc tgtttgtatt tttcaatatg aaaatctggt
     9061 tttccaaaat tagtcttagt ttgtgtctta accgctccct taagcgcctc tttaagataa
     9121 gcactcatag cagattcttc attaataatc ctgcaatttt ttcaaaccaa gattttcaaa
     9181 ctgctttttc acatagtcat tcacatccga ctctaatttc cagtttacta acatattatt
     9241 ttctttcatt aaaacactgt cgcttcttct agcgtaaact tgacattatc ttcaatccat
     9301 ttacggcgtg gttctacctt atctcccatg agaacattga cgcggcgttc ggcgcgcgct
     9361 aaatcttcaa ttgtgacacg gatgagggta cgtgtttctg ggttcatggt tgtttcccag
     9421 agctggtccg cattcatctc accaagtcct ttgtatcgtt ggagggtagc gcctttaccg
     9481 aactgtttac ggagttcttc tagttctccg tccgtccaag cgtaggccac ttcttctttc
     9541 ttgcctttac ctttggacat cttgtaaaga ggtgggaggg caatatagac atgacctgcc
     9601 tcgactagcg gacgcatgta acggtagaaa aatgtcaaga gcaaggtctg gatatgggca
     9661 ccgtcggtat ccgcatcggt catgataatg atcttatcat agttggcatc ttcaatagag
     9721 aagtctgctc caacacccgc accaatggta taaatcatgg tattgatctc ttcatttttg
     9781 aggatatccg ccatcttggc cttggctgta ttgataacct taccacgaag aggtagaata
     9841 gcctggaact tgcggtcacg accttgtttg gcagaaccac cggcagagtc cccctcaact
     9901 agatagagtt cattcttagc aggattctta gattgggctg gggtcaattt cccagacaac
     9961 aagcccttat ctttcttgtt tttcttccca tttcggctct catcacgcgc cttacgtgct
    10021 gcttcacgag catcacgggc cttgatagcc ttgcggatga ggttagaagc taattcccca
    10081 ttttccataa ggaaaaaggt caacttatca gccactattc catccacaac tgggcgagct
    10141 agggggcttc ctagtttatc cttggtctgt ccttcaaact gcaagtgttc ttcaggaact
    10201 aagatagaaa gaacggccgc tagtccctca cgatagtctg aaccttcaag gtttttatct
    10261 ttttccttga gaagacctgt tttacgtgca tagtcattca tgaccttggt aatggcagac
    10321 ttgagtcctg tctcgtgcgt tccaccgtcc ttggtgcgaa cgttattgac aaaggataga
    10381 atgttatctg agaatccgtc attgtactgg agggctactt ccacttgaaa accattgtct
    10441 tccccttcaa agtaaagaac tggcgtcaag atttccttat cttcgttgag ataagaaaca
    10501 aaatcttgta ctccattctc atagtggaac tcaatcgctt catctgttcg cttgtccgtt
    10561 aaagacaagg tcacattttt caagagaaag gctgattcat taaggcgctc tgaaatggta
    10621 ttgtacttga aatctgtcgt agaaaagata gtcgcgtcag gcataaaagt aactttggtg
    10681 cctgttttag acttgagtgc tgtaccgatt ttcttcaaag tcgtgacagg ttttccacca
    10741 ttttcaaaac gttgcttgta aactgcgcca tcacgggtaa tttcaacttc taaccagcta
    10801 gaaagggcgt taacaacgga agaacccact ccgtgaagtc cacctgatgt cttatagcca
    10861 ccttgaccga atttccctcc ggcatgaaga atggtaaaga taacctcaac agttggaatt
    10921 cccatagcgt gcatacctgt cggcatccca cgtccatggt cttgaaccgt tagactaccg
    10981 tctttattga tagttacatc aatacgatca ccaaacccag acaaggcttc atcgactgca
    11041 ttatcaacga tttcccaaac taggtgatga agaccagcgc catcggtcga tccaatatac
    11101 atccctggac gttttcggac cgcatccaac ccttctagca cctgaatagc atcatcatta
    11161 taattgttaa tattgatttc cttttttgac acaaggaacc tcctattcgt tcatctttac
    11221 tattctacag gttttccaag gattttgcaa aatttttctt tctccgatgt gacaatttca
    11281 gcagagattc tctgcttttc tttcccaatt catgatataa taggagtatg attacaatag
    11341 ttttattaat cctagcctat ctgctgggtt cgattccatc tggtctctgg attggacaag
    11401 tattctttca aatcaatcta cgcgagcatg gttctggtaa cactggaacg accaacacct
    11461 tccgcatttt aggtaagaaa gctggtatgg caacctttgt gattgacttt ttcaaaggaa
    11521 ccctagcaac gctgcttccg attatttttc atctacaagg cgtttctcct ctcatctttg
    11581 gacttttggc tgttatcggc cataccttcc ctatctttgc aggatttaaa ggtggtaagg
    11641 ctgtcgcaac cagtgctgga gtgattttcg gatttgcgcc tatcttctgt ctctaccttg
    11701 cgattatctt ctttggagct ctctatcttg gcagtatgat ttcactgtct agtgtcacag
    11761 catcgatcgc ggctgttatc ggggttctgc tctttccact ttttggtttt atcctgagta
    11821 actatgactc tctcttcatc gctattatct tagcacttgc tagtttgatt atcattcgtc
    11881 ataaggacaa tatagctcgt atcaaaaata aaactgaaaa tttggtccct tggggattga
    11941 acctaaccca tcaagatcct aaaaaataaa acgccagttc tgtactgccc ccaaacagtt
    12001 agacaaataa tttatccaaa ggatttagtt ctgtattgca caggg
//
LOCUS       DAVLBN010000058        11961 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLBN010000058 DAVLBN010000000
VERSION     DAVLBN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.058"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..674
                     /locus_tag="VXC24_001702"
     CDS             <1..674
                     /locus_tag="VXC24_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0493785.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..1519
                     /locus_tag="VXC24_001703"
     CDS             1358..1519
                     /locus_tag="VXC24_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493786.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1611..3290
                     /locus_tag="VXC24_001704"
     CDS             1611..3290
                     /locus_tag="VXC24_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0493787.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3558..4124
                     /locus_tag="VXC24_001705"
     CDS             3558..4124
                     /locus_tag="VXC24_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493788.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4446..4634
                     /locus_tag="VXC24_001706"
     CDS             4446..4634
                     /locus_tag="VXC24_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0493789.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4696..5454
                     /locus_tag="VXC24_001707"
     CDS             4696..5454
                     /locus_tag="VXC24_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0493790.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5512..6366
                     /locus_tag="VXC24_001708"
     CDS             5512..6366
                     /locus_tag="VXC24_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0493791.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6478..7362
                     /locus_tag="VXC24_001709"
     CDS             6478..7362
                     /locus_tag="VXC24_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0493792.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7501..7602
                     /locus_tag="VXC24_001710"
     CDS             7501..7602
                     /locus_tag="VXC24_001710"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0493793.1"
                     /translation="MNTLGDKLMELSAIYHRPESEYAYLYKDKKLHI"
     gene            7666..9264
                     /locus_tag="VXC24_001711"
     CDS             7666..9264
                     /locus_tag="VXC24_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV0493794.1"
                     /translation="MEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTE
                     GQNILYGDKGCVENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFAN
                     GNALLNPEGTLDWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSN
                     HKYNTTDYFEIDRYFGDKETFRELVDQAHHRGMKVMMDAVFNHIGSQSLQWKNVVKNG
                     EQSAYKDWFHIQQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATY
                     WIEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHA
                     VMNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWT
                     ANEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNF
                     MKRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEA
                     VALASNCQELENQLVISPDGFVIF"
     gene            9539..9994
                     /locus_tag="VXC24_001712"
     CDS             9539..9994
                     /locus_tag="VXC24_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493795.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            10439..10915
                     /locus_tag="VXC24_001713"
     CDS             10439..10915
                     /locus_tag="VXC24_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493796.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            10915..11676
                     /locus_tag="VXC24_001714"
     CDS             10915..11676
                     /locus_tag="VXC24_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV0493797.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT         4331 a         1640 c         2465 g         3525 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact ctcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagcaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag tccaaactta
     1561 aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact atgtcaaaag
     1621 aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata gaggggtatt
     1681 cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat tatgaaattg
     1741 ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga atacagttca
     1801 atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt cttgtgttta
     1861 agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag ataatgcagg
     1921 attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa gatgctggga
     1981 aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac atccgtattc
     2041 aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa atggaatggt ggctttgctc
     2101 cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag gcagttgcaa
     2161 taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg atatctaaat
     2221 acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat cctttgtttg
     2281 atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa atagcatttg
     2341 gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag gttgaacaag
     2401 atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa gtttggcaag
     2461 ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag
     2521 atacacgcac acacttgctt tctggaattg taaaatgccc gatatgtgga gtgggaatgt
     2581 ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa gtataaagat ttttattact
     2641 atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt aagcaaatta
     2701 gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta agtaatccga
     2761 aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct gaaatagaaa
     2821 aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag tttaagctaa
     2881 ttgaggaaat agataattta gatgttgaag ataagcacta taagagaagg aaacaggatt
     2941 tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca tcactaattg
     3001 atgcgaaagc aaagaaacag actattgaag ctgaaaaact tacaggagat aacatatata
     3061 aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag cgtaggcagt
     3121 taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct aacggacaat
     3181 ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac atagatttgg
     3241 acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag
     3301 gttccccaaa ctttttgagt cccactgacg catcacgctg aggcggtatc actgcttgta
     3361 cgagttgaag catcagcgaa gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg
     3421 aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa atatgatgag
     3481 atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc ctgataatga
     3541 aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat tctaaagatt
     3601 tagtagcatt tgattccata gaagatggga aagcctttgt ggctcaaatc ccgggataca
     3661 ctctggaaac agaagatggt tttgaagtgg agtattttaa tcctaaaaac ataccggatt
     3721 atatggaaat tatttttaac ggaaatattg ttcctttatc taaatttatg ttcgatcctg
     3781 aggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa aatgatagag
     3841 tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa gttaaagcct
     3901 atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa agccgcggat
     3961 atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt tacagaaaaa
     4021 aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta gagattgaag
     4081 atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc aaagttcctt
     4141 gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg ggggaagaaa
     4201 acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag ccgctcataa
     4261 tttatactag atttgataac tgatttgaga cagattttat ttctataaat attgtgaaaa
     4321 ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact tttaaactaa
     4381 tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa cttgaggtga
     4441 tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa aatctagaga
     4501 aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta acaaagtccc
     4561 aggttattga attactccta aataccgttg attatttcga tgatattatg ggggctattt
     4621 actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta acactagtga
     4681 tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag tgaggtttca
     4741 attaataaat accatgctca agtaggtgcc tacttacaag gagaagaagc tgttttatat
     4801 caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga ttatataatg
     4861 gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga ctatcctatt
     4921 gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga gattgtgaat
     4981 atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt ctttactgga
     5041 agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga ctatcctata
     5101 tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt agatggtcgc
     5161 gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc aagtgtaatt
     5221 gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga tatcggtgtt
     5281 actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt gggaaattat
     5341 ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga aatggtaaaa
     5401 ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttgtttt ctaaaataaa
     5461 tatggtatat aaccaatata aaaagcatca aaatgaacaa ggaggaatct gatgcttgga
     5521 gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa aacaaaggac
     5581 tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac ctgtgctgtt
     5641 gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat gaagaaatat
     5701 ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct aaacagcgat
     5761 aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc tccatgtgct
     5821 tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc tagaggactt
     5881 acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg cgctatggct
     5941 acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag agagtacgag
     6001 caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta tatagaaaaa
     6061 gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta tcgttttaac
     6121 gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag tagagacttc
     6181 gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct cgcagcaatc
     6241 acttgtaaca tagcagaggc agcttacggt attcctgatt ggatcaagga taaggcctat
     6301 tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag aataaaagcg
     6361 tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata ataggattac
     6421 atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat aaaatcaatg
     6481 aaaaaagtaa tggtaattat caaccctact tctggtggcg agaaggcttt ggattacaaa
     6541 gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa
     6601 aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg
     6661 gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga tgagagagac
     6721 tacattccta agttagggat tatcccaggc ggtacgggta acctcattac aaaacttttg
     6781 gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt aaccaataag
     6841 attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat cggttctctg
     6901 cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat tttaacctat
     6961 gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa ggttgagaca
     7021 gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac aaattacttc
     7081 gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt gattctgaaa
     7141 gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg ggatgttgtc
     7201 gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc agatagtgaa
     7261 ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat caaagtccta
     7321 gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga gaaagccttt
     7381 tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat tccttgcaaa
     7441 tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg taaaatttga
     7501 atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag gcctgagtcg
     7561 gagtatgcct atctttataa ggataagaaa ctccatattt gaattcgaac taagaaaggg
     7621 gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga ggagttttat
     7681 caggatacaa aagaaatggt caagataact tctggtacct tatttgacca ttggcaggtt
     7741 gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga tacagaaggt
     7801 caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca
     7861 attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa ggttcctgac
     7921 tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa tggcaatgct
     7981 ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa gagcgatgat
     8041 ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca agacttgggt
     8101 attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa gtacaatacg
     8161 acagattact ttgaaattga ccgttatttt ggagacaagg agacctttcg ggaactggtg
     8221 gatcaagcgc atcatcgtgg catgaaagtc atgatggatg cggtatttaa tcatattggt
     8281 tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggcg aacagtctgc ttataaggat
     8341 tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa gagagactta
     8401 ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc caatccagag
     8461 gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa tatcgatgct
     8521 tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt tcgtaaggca
     8581 gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac atctcagcct
     8641 tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga tagtatcaag
     8701 gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat caatggagag
     8761 tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga ttcacatgat
     8821 acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc agccttagcc
     8881 tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct agccttgact
     8941 ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat
     9001 gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc agtaatcatt
     9061 tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct ggaatggaaa
     9121 tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta tcttttagag
     9181 aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct tgtcatctct
     9241 ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac atttcatatc
     9301 ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa tgaattgtag
     9361 aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta aagcacatat
     9421 taagctgtta gcaaatcaac aaaaacatag tgatgcagga gcaactattg aagatgaata
     9481 ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc agtgttgcat
     9541 gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc tttttaatcc
     9601 gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag ggagtggaaa
     9661 tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta taatgtggtt
     9721 gattatttta tggaatgcta agccggatac acctttattt aattttaaag acgaagtaat
     9781 taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata ctactataaa
     9841 gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag cggataacga
     9901 tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg atatgaaaga
     9961 ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg ggtattctat
    10021 aaaatatcct aattgagatt taaatagtag actatacaat atagttaaaa tatcagtaaa
    10081 aacaacactt tattgaggta ttggatacgc tttgctaata gcctaataat cacatgtgga
    10141 gtgttgctac aacgaaaaag gtgataatcc ttaatttcaa gctattttat aagcattttg
    10201 tctttgtaga taaaggcaat tttgacaata aaaatcctaa aaggtgaatc gttatagatg
    10261 tatttgtaga tattgtttgc gcatcgaaaa aattaataca agaataaata tttatagctc
    10321 tttaggtgac ttttatagaa gtaaagttta ggatagaaaa acaagaaata acgcaccatt
    10381 tttggtgcgt tatgcttttt tatgctataa tggatttata aaaataaagg agtttgctat
    10441 gattggaaag aacataaaat ccttacgtaa aacacatgac ttaacacaac ccgaatttgc
    10501 acgaattata ggaatttctc gaaatagtct gagtcgttat gaaaatggaa cgagttcagt
    10561 ctctaccgaa ttaatagaca tcatttgtca gaagtttaat gtatcttatg tcgatatcgt
    10621 aggagaagat aaaatgctca atcctgttga agattatgaa ttgactttga aaattgaaat
    10681 tgtgaaagaa agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg
    10741 aattagcatt gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt
    10801 gattcagaca aatatctatt tagtagaaaa ttttgatgaa atagagagat atagcggcta
    10861 tttggatgga attgaacgta tgttagagat atctgaaaag cggatggtag cttaatggaa
    10921 atccaagatt atactgatag tgaattcaaa catgctttag caaggaatct tcgttcactg
    10981 acaagaggaa aaaagtccag taaacaacct atagcgattt tgcttggagg tcaaagtggt
    11041 gccggtaaga ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc
    11101 atagatggtg atagttttcg ttctcagcat ccacactatt tagaactgca gcaagaatat
    11161 ggcaaagaca gtgtagaata taccaaagat tttgcaggaa aaatggtaga gtctttagta
    11221 acaaaattga gtagtttgag atacaatctt ttgatcgagg gaactttacg aacagttgat
    11281 gttccaaaga aaacagcaca actcttgaaa aataagggat atgaagtaca attggcctta
    11341 attgcgacaa agcctgaatt gtcgtatcta agtactctta tccgttatga agaactgtac
    11401 attatcaatc caaatcaagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat
    11461 catctagttg ataatacacg acaattggaa gaactggcta tctttgaaag aattcaaatt
    11521 tatcaacgag atagaagttc tgtatatgat tcaggagaaa atacaacttc agcagcagat
    11581 gttcttcaag agttactgtt tggggagtgg agtcaggtag agaaggagat gttgcaggtg
    11641 ggggaaaaga gacttaatga attacttgaa aaataaacaa ttgatatttt taggagagta
    11701 gaaatgagag ggtttaataa caagataaag tctgtttatc aagaactaac aaattccaaa
    11761 gagaaattcg gtagctttca caagacttta attcatttgc atacacctgt ttcttatgat
    11821 tacaagctat tttctaattg gactgcaacg aaatatagaa aaattactga agatgaacta
    11881 tatgatatat tttttgaaaa taagaaaata aaagttgata agacaatttt tttagtaatt
    11941 ttgataaggt tgttttttct a
//
LOCUS       DAVLBN010000059        11278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLBN010000059 DAVLBN010000000
VERSION     DAVLBN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.059"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            111..281
                     /locus_tag="VXC24_001715"
     CDS             111..281
                     /locus_tag="VXC24_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493798.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(274..513)
                     /locus_tag="VXC24_001716"
     CDS             complement(274..513)
                     /locus_tag="VXC24_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493799.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            631..903
                     /locus_tag="VXC24_001717"
     CDS             631..903
                     /locus_tag="VXC24_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493800.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            900..1115
                     /locus_tag="VXC24_001718"
     CDS             900..1115
                     /locus_tag="VXC24_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493801.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            1094..1282
                     /locus_tag="VXC24_001719"
     CDS             1094..1282
                     /locus_tag="VXC24_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493802.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            1294..1635
                     /locus_tag="VXC24_001720"
     CDS             1294..1635
                     /locus_tag="VXC24_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493803.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            1636..1866
                     /locus_tag="VXC24_001721"
     CDS             1636..1866
                     /locus_tag="VXC24_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493804.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            1880..2602
                     /locus_tag="VXC24_001722"
     CDS             1880..2602
                     /locus_tag="VXC24_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0493805.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            2595..3077
                     /locus_tag="VXC24_001723"
     CDS             2595..3077
                     /locus_tag="VXC24_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0493806.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            3077..3436
                     /locus_tag="VXC24_001724"
     CDS             3077..3436
                     /locus_tag="VXC24_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493807.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            3436..3921
                     /locus_tag="VXC24_001725"
     CDS             3436..3921
                     /locus_tag="VXC24_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493808.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            3884..5077
                     /locus_tag="VXC24_001726"
     CDS             3884..5077
                     /locus_tag="VXC24_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0493809.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            5095..5412
                     /locus_tag="VXC24_001727"
     CDS             5095..5412
                     /locus_tag="VXC24_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493810.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            5412..6239
                     /locus_tag="VXC24_001728"
     CDS             5412..6239
                     /locus_tag="VXC24_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0493811.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            6259..6765
                     /locus_tag="VXC24_001729"
     CDS             6259..6765
                     /locus_tag="VXC24_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493812.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            6938..7759
                     /locus_tag="VXC24_001730"
     CDS             6938..7759
                     /locus_tag="VXC24_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0493813.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            7762..9105
                     /locus_tag="VXC24_001731"
     CDS             7762..9105
                     /locus_tag="VXC24_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0493814.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            9398..9553
                     /locus_tag="VXC24_001732"
     CDS             9398..9553
                     /locus_tag="VXC24_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493815.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            9550..10245
                     /locus_tag="VXC24_001733"
     CDS             9550..10245
                     /locus_tag="VXC24_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0493816.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            10403..10663
                     /locus_tag="VXC24_001734"
     CDS             10403..10663
                     /locus_tag="VXC24_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0493817.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            10663..11121
                     /locus_tag="VXC24_001735"
     CDS             10663..11121
                     /locus_tag="VXC24_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493818.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            11169..11237
                     /locus_tag="VXC24_001736"
                     /pseudo
     CDS             11169..11237
                     /locus_tag="VXC24_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT         4002 a         1874 c         2472 g         2930 t
ORIGIN      
        1 tacttcatca gcgaatctac aacgtacaga gaagcaaaaa tagcgtgtga gaagctattg
       61 aaacaagtca gccacgagat tgaactcagg gcgatggaaa gtaggacagt atgaaagaag
      121 cagtaaagga atttctaaaa ttcaggagcc gatttacaaa aatagaatgg tttgaaatca
      181 accaagctgt cgaagctcgt ttaaatcaaa aagccgacca gttgaaactg gacgacgtag
      241 atttagaaat catttctagc agactagaaa aagttatcta gaaacgattt gaatgaacat
      301 tggatggata cgatagtcag cgccacgata gtgaatgtag atataatcct gatggtacat
      361 cgagtttgct tcaggtttag aaattggtga gtagagttct gcattttctt cccaccaaat
      421 gtaaggacta gccatatttg gtcccattac acaatcgtcg tcggctgata ggttcaccca
      481 atttccgcaa agacatgcgt gaatttcagt cataatatta cctcctttct ggtttcatta
      541 tagcagaaaa ggagatagca aaaaagcacc tgacggaaat caggcgcata cttaaatatt
      601 caacatgatt ataacacgaa aggagcaaaa atggaagcag ttgaaattgt aagaattaaa
      661 gatgtgatta ttgaaaaagt ctctgctaat gatgaagagt taaaacgtat ctttggatgt
      721 tcaaaacgac aagcaggaga gcgaagaaga gaaatgcaaa aactccctag tcagcaaaaa
      781 catcttttgg atagtggaca acttgtaacg attaaaggtt tctatgaata cttgcaatat
      841 cgtggaacta aagcttggaa aaaagaaatg gaaacaagca agaaaatgag gtcagcagga
      901 tgaacctact atcaagaatc aaaaactatt tttcggaaga ggtcaaagaa actaatctcg
      961 actggaaaga ggtcgcttta gacctcaatc aatcactaat tgaaacacag gaaaaacttc
     1021 aagaagcgaa tcaagaaatc gcagacttga agaaaatcgt agcaatctat aaagaaaagg
     1081 agaaagaaaa acgatggaat atatttacct ggtaacaatc gtaggaattg gactatggtc
     1141 gctagtaaat aaactagatg accacgctga aatgaaacaa aaagagcgcc agctgatggc
     1201 aaacaatgtc gcacggatga atctgagaaa ttcagataag caatttactt atgatgtaga
     1261 accgcctgaa gggttgaaat aaggaggaga aacatgactc aagctgaacg aattagggaa
     1321 tattatagag agcaccctgc tgcctcatat gatgaagtgg ctgaggtcgt tggtacaaca
     1381 aatagtaatg tgagagcgaa cctggccaaa gacatcaagg caggcagatg cgttcgcttg
     1441 gaagataagt catacgatta ctcgccttac tataaccata cacaggcact cactgagttg
     1501 gttgactgga agaatgacaa cagacgtgag tgggtggata tgctgacaag agcagcagag
     1561 aaagaaacgg atagcaacgt tatgcgtttg ttaatcaaag aagcaaataa attgatgaaa
     1621 gaggtgacta agtagatggt acgaaataaa ataggtgatt taactaacac gctcttcgct
     1681 caattagaga ctctggatga tagggatctt acagcagatg aattaaaagt agaattacac
     1741 cgctcgaaac aaatggtcgc aatctcaggt caaatcttac aagcaggtca attggcgcta
     1801 gatgctgaaa aattcaaaga caaggtaggt gaagtcaatg ccccgatcgc tttgctggaa
     1861 ggatgagtac acggagtaca tgcatgaaat atgccctggt cgtttaactc ctgaagtaac
     1921 caggttgctg aatgaaaaat ttggtacgaa ttataacaag agtcaaatcg gtggcgtacg
     1981 caaacgtcta gggttagcag ttggaaaagt ctatcaaggt cgattgctga caaaggagca
     2041 acatgattat cttgtattga tccaaaaaaa taagatttct cgtaatgtcg caaatgaaat
     2101 gaaccaaaaa tttggcttat cgctaactga gaaacagatt aagagttatc ggagaaataa
     2161 taatctacat agtggtttga caggaagatt cgagaaaggt cagactcctc acaataaggg
     2221 gaagaagtac cccaatatgc caaaaaacgg cgggcagttc aaaaaaggta atcgacctcc
     2281 gaattatgta cctgtcggta ctatcaacta cacaacaaac ggttatccaa aagaaaagat
     2341 tggagaacct aatcaatggg ttttgaaaca ccgcaaggtt tgggaggacc atcacgggct
     2401 gataccaaaa gggtactcaa tcgtttttct ggacggtgat aaaacaaact atgatatttc
     2461 aaatctggca tgtttatcta agaacgaaat tgctagaatg aatcaaaatc atttattcac
     2521 gtccaacgct gatttgacta aatcaggtat tggactaaca aaacttacaa ataaaatcag
     2581 agaggtagaa aaaaatggct agtttatacg aactaacagg tcagttcctg acaatttacc
     2641 aattggatat cgatgacgaa acaaaagcag acacgcttga ggccatcgat tggcaagaac
     2701 aatttgaaca gaaagcagaa ggatatgccc atgttatcaa gaatctagaa gccgacgtgg
     2761 caatgtacaa ggctgaggaa gagagcttca aagccaagaa acaggtggca cagaaaaagc
     2821 tggattatgt caaggataac attatggcag ctatgaatgt cacggggcaa accgaagtta
     2881 agagtggtgc cctgattata aaaattgcta agaatccaga atcagtcaag gtcaacgaag
     2941 acgaccttcc gaaaaaatat tttacaaaaa aagtgacgct tgcgccggac aaaaaaacac
     3001 tcaaagagtt gcttaaatct ggcaagaaag tcaaaggtgc ggagcttgtc cggacagaaa
     3061 agttggtgat taagtaatgg aattgatgaa taaaacacga gtaacagatt cactagcagt
     3121 tgtgattgga ccagaatcga ttgaagtact tgttactgaa ggttttctat ttgatgttgc
     3181 gattcgtttt gtaaaagtag acgaaacaaa tcttgatcaa ggaaatgaaa agccagtatt
     3241 cactccggaa tacaagctgg tcacagttgc taaatacaag gaaaaaccta tctttgaatc
     3301 ggaggaagat attcgaaaat ttgagaagca agcaaaagaa gttaaatcgc tatttgcctt
     3361 tgcaaaggta aataaacaaa attggtttaa cactgccctt tatccaggag tgctgactga
     3421 gaaagttggt gtttgatgaa aattttagct attgatccaa gtagtaataa aattgaaacc
     3481 agcacaacag gagttgtctt gttggataat gcaagattag ttgatagctg ggttgtctct
     3541 tatggtatga gaggtttcgc tgattggttt cacgaaatcg gaacaaatct tgaattcgat
     3601 gtagttattg ttgaagaatt taaggcgagg gataacgaca agtcgaaaga taatagcgtg
     3661 gcagaaacca tcgcctatat ccaactttgc tatccaggtg ccattcttca attcaatgca
     3721 ggttacaagt cggatattcc aaacgatctt ttgaaaatct tagacctttg gaaatttgaa
     3781 aaaagtcatc atcaagatat tcgagcagca gcaagacttg gattattttg ggcaatgaga
     3841 aatgatattg aagaagtggt tcatgatatc ggaaaggtgg tgagtgagta tcacaataac
     3901 gctaagaaag tggcaagctg aagcgattaa aagaagtgaa catttatcta atggaatctt
     3961 tttagaggct cttgggggca gaggcaaaac tatctgtgca cttgctattg caaaacataa
     4021 aaaagctaaa aaaatcatca tcacaaacaa tcgactagct attctgaatg gttggataga
     4081 tgcagtcaag tttatgaatt ttgataaagg tgttgagatt atcattcaga cagatagata
     4141 tcttcaaaat caagtcaaaa aggggcataa attagattgt gatgtgctga tagtagacga
     4201 atggcagaat atgtcttctg acaaacaagt ggccttatat cgcaaaataa agcgaaaata
     4261 cacgataggt ctttcagcga caccaattcg gaaaaaagga caaaatttct atccgcttga
     4321 aaaaacggta tttggttggg caaccccaaa taataaattt gactggcaaa agactcatgg
     4381 aaaaatggtc tatgatccat ttagctattc aaaagagaag tgggaagatt ttcaaaatta
     4441 tgaaagttat atctcgagct tgcctaattt cttccgctgg gaagagattg aaggaattga
     4501 gaatgcagtt gagaataacg gttttgagat taagttttac caaaagagag tcgcctctgg
     4561 caatccagaa aaacttgcag aatttagaaa actaaatctt gtaacagtgg acggcaaaac
     4621 tgcaatggcc aagcaatcgt ttggaagaaa gacctttgaa cgctacctta atcaaacagg
     4681 cgtagcagtc gattttccaa aattaaagcc agtaaatgcg gatacgccat tgatgttaca
     4741 acttgacggt ttaatcgaac gagcaccaca cgatatgttg attgtcagta aatctaagca
     4801 gattgtcaac gtcattagcg agcgccatcc tgaaattgga atctggacgg gcgatattca
     4861 agaaggactt tataagaaat tcgtggttgc tactagtcaa gtgttaggtg tcggagtaga
     4921 cggcttgcaa cacaaatacc aaactattgt cgtattggat ccagtagaag aaggttctgg
     4981 agaatatgat gattatcgac aattgctctg gcgcataaca ggaagtcgtc agcagcatga
     5041 tgtaaatgta attgaatttt attataaaga aagttaaaaa aagaggaaaa caaaatgaat
     5101 aaaacaactg aaatgatcgt atttcgtagc cgtaaaactg gagaatttct taattcttac
     5161 aaggacagaa gttctttagc atttgcagct gacttttgca gcttggaata ttgtttgaag
     5221 cttcctcgta aaaaatacga agacaacaaa aagacttaca aggctcttgc tgcagctttt
     5281 gactgtgaaa ttgtcgcagt tgaagcggaa tacaaattga cctatccgaa tggatcagaa
     5341 gttgaaccta tcaagcgtga ccgttcatca attgaggaca tgattaagga tattattgga
     5401 ggggttctct aatggcattt acacttccag caaataaacc acaagttcct aaagataccc
     5461 cacgaaattt tttcatctac ggcgaaacca tgagcggaaa gtcttatctt gcaaatgaat
     5521 tcccaaatcc aatcgttttg aacacagacg ggaatgcaga agctaacact gttccaagca
     5581 ttcagctgat caatgaaaaa gatgacaagg gacgaattac caattcagta attaagcagc
     5641 ttggagatat cttgcttgct ctccagacac agaagcactc ttatgaaaca gtcgttattg
     5701 atgtaattga cgatgttatt gaaatgatta agattgcagt ttgtgatgaa ttaaccccag
     5761 ttggtaaacc tcgcttgaaa tccttgtcgg aaattccata cggcaaagga tacgacttct
     5821 ttaaccaagc tatcacagaa ttagtcattg acctcaaagc attgccaatg aatgttattt
     5881 acatcagccg tcaggtatct gaatatgatg acaatggcaa tgccaccaaa gacaagccaa
     5941 gcttgaaaga taagtatgtc aatcttatca atggaaactc tgatttgatg atccacactg
     6001 aaaaactcgg caacaactac aaccgtgagg ttgaccgcaa gcgtaagacc tattatgcgg
     6061 accaggttga tgacaaggcc atcttgaaaa tcttggcaac tatccgtggg gctgttgagc
     6121 ctgcaaaggg caagctagcc cctaaaaaag aagcagctaa gacaactaaa ccagctaaga
     6181 ccgaaaaaac aaaagaggca cctaagaaag aagttgactc tgatgatgaa ctattttaag
     6241 aaataaagga gaatacacat gagcttacta gatatcgcaa aatcaatcaa aaaagagggc
     6301 tttgacccac gcaaagacag cgccaacggt cctgcaccaa tcccagctgg tacttatcca
     6361 gtagtcctga agaaagcaac cttcaacgta tcggacaaag gctgggaaag ccttggttat
     6421 caatttgaaa tccgtggcgg tgattacagt ggacgctctg aatttgcaac atttggcaca
     6481 ctgactgaat ggaacggtaa gaaccttgac tgggcagttg aacgcactat gaaattcttt
     6541 atcaaagcct tggtccttgc tggcgacagt atgcaaggaa atgaagaaga cggtaaagcc
     6601 ttggaagagg ctctacaacg taaggcagtt ggctcttact acaaccttgt tatctctgtg
     6661 actaagggga aagatggccg tgagttccga aactatgacc ttgaagaaga agaagcacaa
     6721 ccgctgactg aagctgatat cgatgaagat gacctccctt tctaaaaaat agcaagtttt
     6781 gggtcattga tgaaactgat gaaagattag gaccattcaa tacatttgaa gaggcttatc
     6841 aatcgttgtt attttattta aaaatgactg aagatgaata tcagtcaaac tatacggccc
     6901 aggaacttgt ttatatttac aaagaggaga aaaaaccatg ccgtcgatga aagaatacgc
     6961 attacagtac caaaagttag ggttctcagt cattccaatc aatcctaaaa acaagatgcc
     7021 tttaatcgaa tttgctgata aaccagccat gactccatct gagattgaaa acttttggga
     7081 cggctaccct aatgcaaaca ttgccctaaa gactaccaac ttctttgtca ttgatattga
     7141 caaacacggc aaatcgaacg gttttgaatc gctaaaaaaa tggaaacatc taaatttaat
     7201 cgaaccgaca ctgcaagcta agacggctag tggcggtaaa catctattct acttcaaacg
     7261 agaagatgag ccgatcactc agatgattgg attcttgcct ggtgttgata ttaaggctca
     7321 cgaaaataat tatgtgttag tcgcaccctc tgccacagat aaagggcagt atgagtggga
     7381 tctggaaaag tctaaggaag gtggcacgat ggtcactcct tcaaaatatt taatccagtc
     7441 tataaaaaaa cagtatggcg aaactcacgg ttataagtat gatggtaagg acggtcttag
     7501 ggatttagtt agacgttcac atactagaga ccgaacacag actacagatc tctttgaaac
     7561 catcgccctt ggttttggtg atgaaggtgg acgaaatgac aaactagcaa aattcgtagg
     7621 tggtctctta tatcgtgcgg tcgacgatgg tgtagttgtt caacttgcaa gattagcaaa
     7681 tgcaaatagt ccaacccctt tgcctgaaaa ggaaatgatg cgtactattg aaagtatgat
     7741 taaaaaagat aggaggtgat tgtgattggt aatgtagtaa gtattgactc acaacctaag
     7801 atgataacga ctgccaaggg agacatcaag gccaacagtc caagtaatgt gttgatgtct
     7861 ttcaaagctg atgatcagtt gagtatttac ctaaagcaca acgatttttc ccaagagcat
     7921 gaactcctta aagatatcaa gatcggcaac actcttttta aaaaaggtga gctcccttct
     7981 aactttgatt cagtcgtaaa agtttacttt gaaagtgtgt taggtgttgc tttctctagc
     8041 caggcgatgc tggacggcat ggaaactttt ttctcagaac gttcttacaa tccagtcatt
     8101 gagtatatgg aaaaggctgc tgaaaaatgg gatggtcgta aacgaattga ccgaatgctt
     8161 caggtttacc tgggggctga agatatccct ttagtttcta aaatcgctca aatgtggcta
     8221 gttggtgcag ttgctaaagt ttatgatcca tacgttaagt ttgactatgt tctggatcta
     8281 gtcggtggac aaggagttgg gaaaacatcc ctccttcaaa aattgggtgg cgaatggtat
     8341 acggatgccg taacagattt ctctaataaa gataattacg acattatgtt aaagagtcta
     8401 atcgtcaacg acgacgaaat ggtggccagt aatcggatga gctttgcaga aactaaggcc
     8461 tttatttcta aaactagcct acgttatcgt aaaccataca tgaaacgcac agaagagttt
     8521 gccaaaaact tcattttagc tagaactact aaccaaacag aatacctcaa ggacaaaacc
     8581 ggtgaacgtc gttttctacc agttatggca gatagtaaac ggcaaaaaaa acatccaatg
     8641 gaaatcgagc cagagacaat tgaacaaatc tggggcgaag ccgttacaat ctatcgtgct
     8701 ggtgctgatt tgatgtttga tgaaaataca gaggatgaac tgaatatcta ccgtgaacag
     8761 ttcatgtatc gtgatgaagt tgaattacaa gtgcttgaat atcttgatat gcccgtccct
     8821 gaaaattggc aaaactggtc tattcagcaa caacatcaat acacaagtaa atatttcgat
     8881 aatagtagcg actttgatcc tggaagcaaa aaactagata aggtctcaac tcgtgaaatg
     8941 atgtacaact tatttatgag aaattcgaat gacaggaagc tgtcaacgaa gattaacatg
     9001 atcatggata atcatcctga ttggaaaaaa agtgttttcc gggcaggagg taaaagtaca
     9061 aaagggttcg taagagtgaa agattcggaa aaaactaatc ggtagcaatt aaaaaattat
     9121 cggtagtcat cggtagcagt tgagggggag atcggtagca ttctaccgat aaaataggac
     9181 atcggtagca catcggtagc agtctaaccc cttgatatta ctgactttta tttaatattt
     9241 atatataatg ctactcttct acctatattt ttaaaaaaag tatataaaat aatagtaata
     9301 ataaagaaag cctatagaat agggattctt gaaaaaaact ttttactttt tagaatttat
     9361 cggtagcacg gtagcagttt agaaaaaaga ggtaaaaatg tcatacacag taacattatt
     9421 ttttgacaac atggtagacg aaactcactt ttttaagaaa gagagtgatg ctgccaaatg
     9481 caaggctcag ttagaaagca agtatcgagg gaatcgaatg tataaagtta agcaggagaa
     9541 attggaagaa tgaataagca ggaactgatt aaacgtatcg aggatttgcc ttatacagag
     9601 gggcctatcg cagatacaat cgaaattaat agaaattgga tattgaaatc aattgaacag
     9661 ctagccgaat ccgaaatagg tcacgcagat gaagctccac gctacgtaaa gaacatacta
     9721 gcacgattgc gagaattgcc attgcatgat agagagtttt ggttaaaggc tatcatgagc
     9781 gaatttgaac aggattttag ccatgcaaaa tggcgagagg gctacgagca aggtaaaatt
     9841 gagggtatgg ttgaacgtga aaaagtcata gttccgcagt gtgtggcgga atatatagaa
     9901 tttaaaaaga aaaacaattt tcatgtttac ggtgcaatga gagtaattga agatcattat
     9961 gataagaaag ttcctgattg gttttacgaa aataacatcg aaaaattctg tcttgcttgg
    10021 cttgacggct acgaggttga aaaagagaag cggtattttg ttaagattaa agggaatatt
    10081 aaagaaaata tgttggttta tggagaactt ttgaaaaggt atttctttac aaaaagcttt
    10141 agtttagacg atgttatata ttcccacacc cgtaaagaac tagaaaatgc aaaaatcggc
    10201 tgggtgtttg attgtgaagg gtttgagatt gaggaggtgg agtgatgagc cttacgctaa
    10261 atagcacaat tggagactta gttttggcaa tcggagaaat tatcgttggt tctgatggta
    10321 aaaccactac agcgatactg gagatacctg atcaaagctt ttacttagag attgagctta
    10381 aattgaagga ggaggtcata aattgaaacg attcatagct atctggattc tgctatctgc
    10441 tggattgaat atctggcaga gtatctacat taaaaagtta gaagaaaagc gccctattgt
    10501 cgtctataaa gctgataacg caggcgctga gatattcggt aaagtcgtcg agaaaggacg
    10561 gcatggcaag ctatacacgc ttaccattcg tgactacggg gtgttcgtgg ttacgaagga
    10621 cgtgtatgag aaagtgaaag taggggatga ggtgttactc taatggatga tattttacaa
    10681 gctttagcaa aaatgctaaa tatgactgtt gatgaagtaa gttctttgct tacaacattt
    10741 aaagggaatg caccacagat ttatgaaatg ttcgttaaag aaaagatgtt ttatgatctc
    10801 ttcagtcttt ttcaaatcat gtcaattgta atatttagta tttctgcagt agttttagca
    10861 gttttaactc tcatatattt tacatacgat ggtggttttg tttattccta tgatatacgt
    10921 acaggaaaaa ccgaggaaga aattaaatta gaacgcattg aacggaaaag aaaggactta
    10981 aaaataccac taaaaattag ttgcatttca tcaagcgcaa gtttgataac attagttatt
    11041 gcaattgttt taaaagcaac tcttgcacct aattatatat tcatcgtgaa tgagatttta
    11101 ccaaaattaa cgaagagata ggagttatca tgaacgcact agaaaaagtc gaacaatggt
    11161 ttatcgaccg tgaaatcaaa gaccgaaaag gtcgctggat tgatggctcg tttgtcaaag
    11221 aggaggattt ggcatgatac cgaaatttag agtgtgggta aaaataggaa aacgtatg
//
LOCUS       DAVLBN010000060        11176 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLBN010000060 DAVLBN010000000
VERSION     DAVLBN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.060"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            97..459
                     /locus_tag="VXC24_001737"
     CDS             97..459
                     /locus_tag="VXC24_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493819.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            755..943
                     /locus_tag="VXC24_001738"
     CDS             755..943
                     /locus_tag="VXC24_001738"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493820.1"
                     /translation="MENNDSFTKLKESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQ
                     TVLSFLVLTSFFVKNCVK"
     gene            994..1686
                     /locus_tag="VXC24_001739"
     CDS             994..1686
                     /locus_tag="VXC24_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0493821.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1739..4149
                     /locus_tag="VXC24_001740"
                     /pseudo
     CDS             1739..4149
                     /locus_tag="VXC24_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            4399..5101
                     /locus_tag="VXC24_001741"
                     /pseudo
     CDS             4399..5101
                     /locus_tag="VXC24_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            5103..7811
                     /locus_tag="VXC24_001742"
     CDS             5103..7811
                     /locus_tag="VXC24_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0493822.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7907..8398)
                     /gene="tpx"
                     /locus_tag="VXC24_001743"
     CDS             complement(7907..8398)
                     /gene="tpx"
                     /locus_tag="VXC24_001743"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0493823.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8521..9450)
                     /gene="psaA"
                     /locus_tag="VXC24_001744"
     CDS             complement(8521..9450)
                     /gene="psaA"
                     /locus_tag="VXC24_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0493824.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9482..10330)
                     /locus_tag="VXC24_001745"
     CDS             complement(9482..10330)
                     /locus_tag="VXC24_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0493825.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10327..11049)
                     /locus_tag="VXC24_001746"
     CDS             complement(10327..11049)
                     /locus_tag="VXC24_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0493826.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3292 a         2076 c         2538 g         3270 t
ORIGIN      
        1 aaatttttat tttataatat cagaaaatac tttttttttt aaaaagcaaa tatgatacaa
       61 ttttatttga aaaaaaataa aaaaggagat tttattatga aatcaagtgg tatcgtcggt
      121 cttgtgggag gaattttact tcttatttgt ccttttgtct tgttgggaac agcggtaaac
      181 acagctgcta caactcttaa tggaggagct actgcagggg ctttttcagg tgttgcctta
      241 ctcttgaatg ccttgaagat tgcaaatctt gttcttggta tcattgctat tgtttactat
      301 aaaggagata agcgtgtagg tgcagctccg tctgtactaa tgattgtttc tggtgaagtt
      361 agtctcattc cattcttagg atgggttggg gggattcttg ctattatcgg aggatctcta
      421 ttccttgcaa cattgaagaa attcaaatca gaagaataaa aggtatttta gcatgaaaag
      481 aacaaaaaag tttatcggta taggagtagc tctattatct ctttctcttc tagttgcatg
      541 tggaacataa agttcaaaga atacttcaac aagtaatgat gagaagacag tagcaacatc
      601 caatagttca aaagaaacaa tcactttcga tacaccggtt gtaacagacg atgcgattga
      661 atcaatacgc acttatgcag attatataga tctttataaa aatatttttg atgattattt
      721 tactaaaact gaggaaggtt tcaaaggcac agctatggaa aataatgact cgtttactaa
      781 actaaaagag tcaactcaaa aattattcga tgcgcagaaa aaaaggttaa ataatgaaga
      841 tagaatagaa acaaccaaaa acaatgtgat tgccaaacat tgtcaaacag tcctttcctt
      901 tttggttttg actagctttt ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg
      961 aaacctcgga aaatttaaag gagaatccat ctaatggtaa aattggtttt tgctcgccac
     1021 ggtgagtctg aatggaacaa agctaacctt ttcactggtt gggctgatgt tgatttgtct
     1081 gaaaaaggta cacaacaagc gattgacgct ggtaaattga tcaaagaagc tggtatcaaa
     1141 tttgaccaag cttacacttc agtattgaaa cgtgctatca aaacaactaa cttggctctt
     1201 gaagcttctg accaattgtg ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac
     1261 tacggtggtt tgactggtaa aaataaagct gaagctgctg aacaatttgg tgatgagcaa
     1321 gttcacatct ggcgtcgttc atacgatgta ttgcctccaa acatggaccg tgatgatgag
     1381 cactcagctc acacagaccg tcgttacgct tcacttgacg actcagttat cccagatgct
     1441 gaaaacttga aagtgacttt ggaacgtgct cttccattct gggaagataa aatcgctcca
     1501 gctcttaaag atggtaaaaa cgtattcgta ggagctcacg gtaactcaat ccgtgccctt
     1561 gtaaaacaca tcaaaggttt gtcagatgac gagatcatgg acgtggaaat ccctaacttc
     1621 ccaccattgg tattcgaatt cgacgaaaaa ttgaacgtcg tttctgaata ctaccttgga
     1681 aaataaaaaa ttgtaagtct agaattgatt tctaggcttt ttatgttagt atggaagtat
     1741 gataaggaat aaaaaacaag attatgtact ggcctacaag caaccagctt caaccactta
     1801 catgggttgg gaagaagaag ctttaccgat aggcaatggt tctttaggag caaaagtatt
     1861 tggccttata ggggctgaac ggattcaatt taatgaaaaa agtctctggt ctggaggtcc
     1921 acttcctgat agttcagatt atcagggtgg aaatcttcag gatcagtatg ttttttagct
     1981 gagattcggc aggctttgga gaagagagat tacaatctgg ctaaggaact ggctgagcag
     2041 cacctaattg ggccaaaaac gagtcaatat gggacctatc tgtcttttgg ggatattcac
     2101 attgagttca gccagcaagg tacgactttg tctcaggtga cggactatca gagacagctg
     2161 aatattagta aggcacttgc gacgacttct tatgtctata agggaacgcg atttgaacgt
     2221 gaagcttttg cgagttttcc agatgatctc ttggttcaat gttttactaa ggaagggttg
     2281 gaaactctag attttactat agaactatcc ttgacctgtg atttggcttc taatggaaag
     2341 tatgaacagg aaaagtctga ttacaaggag tgtaagttgg atattactga ttctcatatc
     2401 ttgatgaagg gaagagttaa ggataatgat ctgcggtttg ctagttatct agcttgggaa
     2461 acggatggag atattagagt ttggtcatat agggttcaga tatcaggagc cagttatgcc
     2521 aatctcttct tggccgctaa gacggatttt gcccaaaatc ctgctagcaa ttatcgcaag
     2581 aaactagatt tagagcaaca ggtgagagac ttggtggaca cagctaaaga aaagggctat
     2641 acccaattga aatcaaggca tatcgaggac taccaagcct tattccagcg tgttcaattg
     2701 gatttggaag ctgatgttga cgcatccact acagatgatt tgttaaaaaa ttataagcca
     2761 caagaagggc aggctttgga ggagctgttc ttccagtatg gacggtattt attgattagt
     2821 tcgtccagag actgcccaga tgctctacca gctaacctac agggagtctg gaatgcggtc
     2881 gacaatcctc cttggaattc ggactatcac ttaaatgtca atctgcagat gaattattgg
     2941 ccagcctatg ttaccaatct cctagaggcg gtctttccgg tcatcaacta tgtagatgat
     3001 ttgcgtgtct atggtcgtct agcggctgta aagtatgcag gaatcgtctc tcaaaaaggt
     3061 gaggaaaatg gttggttggt tcatactcaa gcgactccct ttggttggac ggcacctggt
     3121 tgggattact attggggttg gtcaccagct gccaatgcgt ggatgatgca aaccgtttat
     3181 gaagcctatt cattttatag ggaccaagac tatctcagag agaaaattta tcccatgttg
     3241 agggaaacgg ttcgtttttg gaatgccttt ttacataagg atcagcaggc gcagcgttgg
     3301 gtgtcttctc cgtcttattc cccagaacat gggccgattt cgattggcaa tacttatgac
     3361 caatctctaa tttggcagtt atttcatgat tttattcagg ctgctcagga attgggactg
     3421 gatgaggact tgttgactga ggttaaggag aagtctgatt tactaaatcc tttgcaaatc
     3481 actcaatctg gtcgaatcag ggagtggtat gaggaggaag agcagtattt tcaaaatgag
     3541 aaagtggagg cccagcatcg gcacgcttcc catctagtgg gactctatcc tggcaatctc
     3601 tttagctaca agggacaaga gtatattgaa gcggcgcgtg ctagcctcaa tgatcgtgga
     3661 gatggcggca caggctggtc caaggctaat aagatcaatc tctgggcgcg tttgggagat
     3721 ggcaatcgag cccataaatt attggcagag cagttaaaga catccacctt gccaaatctt
     3781 tggtgtagcc atcctccttt tcagatagat ggtaattttg gtgctactag tggcatggca
     3841 gaaatgttac tccagtctca tgcagcttat ctggtacctc tagctgccct acctgatgct
     3901 tggtcaacag gttctgtttc aggcttaatg gcacgtggac attttgaagt gagcatgagc
     3961 tgggaagata aaaaactctt acagttgacc attttatcaa ggagtggagg agatttgcga
     4021 gtttcttatc cagatattga gaagagtgtg attaaaatga atcaagaaaa aataaaagcg
     4081 aaatgcatgg ggaaagattg tatttcggtg gcaacagcag aaggtgatct tgttcaattt
     4141 tatttttaag aagatgttat aaggcagtaa tttgaaactg ccttttaata aggatttaag
     4201 aatataagca gttttcaact agttgaaaaa gcgttataat gataatagga agtaatactc
     4261 aatgaaaatc aaagagcaca aacaaggaag ctagccgcag gttgctcaaa acagtgtttt
     4321 gaggttgcag atggaagctg acgtggtttg aagagagatt ttcgaggagt ataatttgtt
     4381 tgatagaggg tgggtctgat ggcttatatt gagatgaaac actgttacaa gcgttatcag
     4441 gttggggaca cggagattgt ggccaatcgt gatgtgaatt ttgagattga aaagggggag
     4501 ctggttatta tccttggtgc ttcaggtgca ggcaagtcaa cagtgcttaa ccttcttggg
     4561 ggaatggata ccaatgatga aggggaaatc tggattgatg gtgttaatat tgcggattat
     4621 agttcccacc agcgcaccaa ttaccgtaga aatgatgtgg ggtttgtttt tcagttttat
     4681 aatctagttt ctaatctgac agctaaggaa aatgtggaac tggcttctga aattgtgaca
     4741 gatgtcttga atcctgatca ggtcttgaca gatgtaggtc tggctcatcg tctaaataac
     4801 tttccagccc agctttctgg aggggagcaa cagcgagtct ccattgcacg cgcggtagcc
     4861 aaaaatccta aaattcttct ttgtgatgaa cctactggag ccttggatta tcagacgggc
     4921 aagcaggttt tgaaaattct ccaagatatg tctcgtcaaa agggagcgac ggtgatcatc
     4981 gtgactcata atggagcttt tggcgcccat tgctgatcgc gtgattcata tgcacgatgc
     5041 cagtgtcaag gatgtggtgc tcaaccagca tcctcaggat attgacagtt tggagtacta
     5101 gtatgatcaa gcgaaaaact tattggaagg acttaattca gtccttcaca ggctccaagg
     5161 ggcgtttttt atccatcttg atcctgatga tgttgggatc tctagcctta gtaggcctca
     5221 aagtaaccag tcccaacatg gaggcgacag ctaatgctta tttaacaact gctcaaacct
     5281 tggatttggc agtcatgtct aactatggct tggatcaagc agaccaagaa gaactaaaac
     5341 agacggaggg cgcagaggtc gagtttggct atttgacaga tgtgactatg gataatgggc
     5401 aggatgccat tcggctgtac tccaaaccag agcgaatttc aacctttcag ctaagaaagg
     5461 gacgacttcc tcagtcagac aaggaaatcg ctttggccac tcatttgcaa ggccaatgca
     5521 gcgtgggaca ggagattagt tttaaagaaa aagaagaggg tcattcctct ttaaaagacc
     5581 atacttatac cattactggt tttgtggatt cggctgaaat cctctcccag cgagatatgg
     5641 gctacgcagg aagtggaagt gggactctga cagcctatgg ggtgatttta cctagtcagt
     5701 ttgatcagaa agtctacaat atagctcgtt tgaaatatca agatttagca ggtttaaatg
     5761 ccttttcatc agcttatgaa gaaaaatcca agcaacatca ggaagacctt gaacaaactt
     5821 tatcagataa tggcaaggta cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag
     5881 acaaggggca agagaccctt gacaaggctc agactaattt gcaggaaggc aagcgtcgtt
     5941 tagcagctgc tcaagctcgt atacaggctc aagaaagtca actagccttg tttcctcaag
     6001 ttcagagaga gcaggctagt gctcaactta cccaagccaa gcaggaattg ggcaaggaag
     6061 aagacaaact aaagcaagct gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac
     6121 atcagcaagt cttggacgat ttggcggagc caaggtatca ggtctataat cgtcagacca
     6181 tgccaggtgg tcagggctat cttatgtata gcaatgcttc atccagtatt cgagcagtgg
     6241 gcaatatctt tcctgtggta ctttatgccg tagcagccat ggtgaccttt acgaccatga
     6301 ctcgctttgt agacgaagag cgaactcatg cagggatttt taaggccttg ggttaccgta
     6361 gtaaggatat tatcgccaag tttctccttt atggactagt agctgggact gtcggaacgg
     6421 ctctaggtag tatacttggt cattatttgc tagccagtgt aatttcaagt gtcattacaa
     6481 aaggcatggt ggtgggagaa acccagattc agttctattg gacctatagc ttactagctc
     6541 ttgtcttgag ctggttggcg agtgtgttac cagcctatct ggtggcttgg agggaacttc
     6601 atgccgaagc agcccagctt ctacttccta aacctcctgt caaaggagct aaaatcttat
     6661 tggagcgtat cggttttatc tggcgtcgtc tcagttttac tcataaggta acagcccgca
     6721 acatctttcg ttataagcag agaatgttga tgacaatctt tggtgtggca ggttctgtag
     6781 ctctgctctt tgcaggtttg ggaatccaat cttctgtagc aggagttccg tctaaacagt
     6841 ttcaacaaat ccaacagtat cagatgcttg tctctgaaaa tcctagtgcg accgatcagg
     6901 acaaggtaga gctagcagaa gtgttgaaag ggcaggagat actagcctac cagaaaatct
     6961 attctaaaac gctagacaag gatttcaaag gcaaggctgg tcttcaaaac attactctta
     7021 tgatgataga gaaggaagat ttgactccct ttatccatct tcaacatcat cagcaggagc
     7081 tgacattaaa agatggcatc gttattacag ctaaactcgc ccagctggca ggtgtcaagg
     7141 ttgggcagac tttagaaatt gaaggtaagg aactaaaggt cgctgctatt actgagaact
     7201 acgttggtca ctttatttat atgagtcagg ctagctatga gcaactttac ggacagctac
     7261 cccaagccaa cacttatctg gtctcattaa gggataccag tgcaactagt atcgaaagtc
     7321 aggcgggctt gcttatgagt caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca
     7381 ttcgactctt cgactctgtc gctagctcac tcaatcagac catgaccatc ttggtcatcg
     7441 tatcggttct attagctatt gtcatccttt acaatctgac caatatcaac gtagctgaga
     7501 gaatccgtga actctccact accaaggttc ttggttttca taataatgaa gtcaccctct
     7561 acatttaccg tgagacgatt gtgctatccc ttgtgggaat cgtacttggt ctggtagctg
     7621 gtttctattt acaccaattt ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc
     7681 cgcaggtagg ctgggaagtc tatgtaatcc cagtggcagc agtaagcatc attttgacct
     7741 tgcttggttt cttcgtcaat tattatctga gaaaggttga tatgttagaa gccctgaaat
     7801 ctgtagagta aggtagttat ttttagctga ttgaacttct atttactaat attcaaaaat
     7861 cctccgtttc aaagagcagg gaactctttg tgacagagga ttttttctat agggctttag
     7921 cagctgcaat tgcggcttcg aagtttggct cagaattgat attatccacg tattcaacgt
     7981 agcgaatcgt attgtcagta tcgaggacaa agactgcgcg tgctaatagg tgccattcgt
     8041 tgatcaagag ggcataatcg cgcccgaaag aatggtcaaa gtagtctgaa agcataatgg
     8101 cattgtcaag gccttcagca ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa
     8161 cagtcaatac gaccgtgttg tccagtccag ccaattcttc attaaaacga cgtgtttgag
     8221 ttgagcagat gcctgtatcg atagaaggaa cgacactcaa gacttttttc ttgccatcaa
     8281 aatcagccag agatttttta gaaagatctg ttgtagtaag agaaaaatca agcgccttgt
     8341 cgccgacttg tagttgttta cctgtaaagc tcacaggatt tccgagaaaa gttaccatag
     8401 gatactccaa tcttttttct tccattgtat ctgaaacagt cagaattttc caatgatttg
     8461 accggaaatg tgggcataga aaaaacgcca gctcacatga gaatgacgtt tttcagaggc
     8521 ttattttgcc aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct
     8581 gtcgccttct ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt agattgggat
     8641 gtttgtgtct tgagaaacag ttttcattgg acggtcatcc acacttgatt ctacaaagag
     8701 tgatggaact tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc
     8761 ttcttcttca gtattgattt cccagatgta ggcacttggg acaccatagg ctttagagaa
     8821 gtatttgaat gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa
     8881 tttatcctta ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt
     8941 ttcatagaat tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc
     9001 aaaaataata ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt
     9061 ttgaccttca aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc
     9121 agttttcttg gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt
     9181 gataccgtta tagaaaatca aatcagcctc agaagttttc ttaacgtctt caggaagtgg
     9241 ttcgtattcg tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc
     9301 agcaatattt ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg
     9361 accagaagtt gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa
     9421 gagaacgagt aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc
     9481 cttattttaa caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga
     9541 agctaatgag aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa
     9601 aactatagcc aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga
     9661 aaatcatgct tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca
     9721 tggctacaat caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga
     9781 gtaccatgag aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt
     9841 catcaaagga agttatcaag agttgcttga agaaaatcca gattaacaag aggatggctg
     9901 cccccacacc catagtaata aacatatccg tatcttggac ggccaggata ttaccaaaaa
     9961 ggatatggaa aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta
    10021 agaaagaaga aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga
    10081 tgtaggtaat gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa
    10141 ggcccaagat gaaggagagg gctacacctg gtaagacagc atgtgaaatg gcatctccca
    10201 tgagtgacat cccgcgtaga ataatgaaac atcccacggc tccagctaca atcccgacga
    10261 caatagctgt tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt
    10321 ctgcaatcat aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt
    10381 ggtttcggta aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa
    10441 gacttgatcg aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt
    10501 cccagctttt ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagagtcaat
    10561 cccagcaaag ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat
    10621 caagacccgc tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc
    10681 taggccgacg atttcaaggg cctcttgcac tttcttccaa tgtttagcct ttaaacttcg
    10741 aaagagagga atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa
    10801 gttgtagtcg atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac
    10861 ttccttgtca tcgagaaatg cctgaccttg atgtgggata attcccaaca taccttttaa
    10921 tagtgttgat ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag
    10981 cactagtgaa atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttcgat
    11041 acgtatcata aacttgtatt cctcctgtct cttaatatac attaaaaaaa aaattaagtc
    11101 aagttaattt ttgaaaaaat taaaataata actgaaaaat agattctaaa aataactttc
    11161 aggataaatt tctaaa
//
LOCUS       DAVLBN010000061        10932 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLBN010000061 DAVLBN010000000
VERSION     DAVLBN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.061"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            36..719
                     /locus_tag="VXC24_001747"
     CDS             36..719
                     /locus_tag="VXC24_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0493827.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            719..1453
                     /locus_tag="VXC24_001748"
     CDS             719..1453
                     /locus_tag="VXC24_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0493828.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            1607..2464
                     /locus_tag="VXC24_001749"
     CDS             1607..2464
                     /locus_tag="VXC24_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0493829.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            2606..3478
                     /locus_tag="VXC24_001750"
     CDS             2606..3478
                     /locus_tag="VXC24_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0493830.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            3760..4443
                     /gene="rpiA"
                     /locus_tag="VXC24_001751"
     CDS             3760..4443
                     /gene="rpiA"
                     /locus_tag="VXC24_001751"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0493831.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            4457..5668
                     /locus_tag="VXC24_001752"
     CDS             4457..5668
                     /locus_tag="VXC24_001752"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0493832.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            5670..6227
                     /locus_tag="VXC24_001753"
                     /pseudo
     CDS             5670..6227
                     /locus_tag="VXC24_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            6227..7036
                     /locus_tag="VXC24_001754"
     CDS             6227..7036
                     /locus_tag="VXC24_001754"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0493833.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            7512..7907
                     /locus_tag="VXC24_001755"
     CDS             7512..7907
                     /locus_tag="VXC24_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV0493834.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEIIEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAAVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            7917..8492
                     /locus_tag="VXC24_001756"
     CDS             7917..8492
                     /locus_tag="VXC24_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0493835.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            8517..9029
                     /locus_tag="VXC24_001757"
     CDS             8517..9029
                     /locus_tag="VXC24_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0493836.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            9687..10397
                     /gene="deoD"
                     /locus_tag="VXC24_001758"
     CDS             9687..10397
                     /gene="deoD"
                     /locus_tag="VXC24_001758"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0493837.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(10420..10932)
                     /locus_tag="VXC24_001759"
     CDS             complement(10420..10932)
                     /locus_tag="VXC24_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0493838.1"
                     /translation="MIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWM
                     LTDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRG
                     KVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQF
                     LDKKRKSYNS"
BASE COUNT         3288 a         1940 c         2528 g         3176 t
ORIGIN      
        1 tcatacagta ttctatttta gaaagcagtg tgactatgaa tttttctttt ttacctaagt
       61 atttacctta ttttaactat ggggctgttg tgacgattct tatttctatc tgtgttatct
      121 ttttgggaac tattttgggt gttgtcttgg cttttgggca acgttcaaag tttaaaccgc
      181 ttgtttggtt ggccaacttg tacgtttgga ttttccgtgg gacaccgatg atggttcaaa
      241 ttatgattgc ctttgctctt atgcatatca atgctccgac tattcagatt ggaattttag
      301 gtgttgattt ttcgcgtctg attccaggga ttttgattat ctctatgaat agtggtgctt
      361 atgtttcgga gactgttcgt gccggaatca atgcggttcc aaaaggtcag ctagaggcgg
      421 cttattcgct agggattcgt cctaaaaatg cgatgcgtta tgtgattttg ccacaagcag
      481 tcaaaaatat cttgccagca ttggggaacg aatttatcac cattatcaag gacagctccc
      541 tcttatcagc tattggggtc atggagttgt ggaatggggc tacaacagtt tctacaacaa
      601 cctatctacc tttaacacca cttttatttg cagcatttta ctacttgatt atgacctcta
      661 ttctgacagt agccttgaaa gcttttgaaa aacatatggg acaaggagat aagaaataat
      721 gacagaaacc ttgataaaaa ttgaaaattt acataaatct tttggaaaga atgaagtatt
      781 gaagggcatc aacctcgaga ttaaaagagg agaagttgtc gttatcatcg gtccttcagg
      841 gagtgggaaa tctaccttgc ttcgctctat gaatttgttg gaggaagcaa ccaaggggaa
      901 ggttatcttt gagggagtcg atattacgga caagaagaat gacctgtttg ccatgcgtga
      961 gaagatgggc atggttttcc aacaatttaa cctctttcct aatatgactg tgatggaaaa
     1021 tattaccttg tcacctatca agactaaagg tgaaagcagg aaagttgctg agaagagagc
     1081 ccaagagctt ttggaaaaag ttggtttgcc agataaggca gacgcttatc cacagagtct
     1141 gtcgggtggg caacaacaac ggattgccat cgcgcgtggg ttggctatgg aaccagatgt
     1201 tttgctcttt gacgaaccaa cttcagcctt ggatcctgaa atggtaggtg aggtattggc
     1261 tgttatgcaa gaccttgcca agtcagggat gactatggtt atcgtaacac atgagatggg
     1321 atttgcccgt gaggtggcag atcgtgttat ctttatggca gacggtgtgg ttgttgaaga
     1381 tgggacacct gagcagattt ttgaacaaac ccaagaacaa cggactaaag atttcttgag
     1441 taaggtttta taatctattt taaaatttca agacaagatt agtgaaaagt tcaaccagag
     1501 ctttttctta tagtttgaaa ctataggata acctaggaaa gaagtgttag agggcactag
     1561 cagtttttgg tataatggaa gatatttgaa agaaaagaga agtgatatga cacagattat
     1621 tgatgggaaa gctttagcgg ccaaattgca ggggcagttg gctgaaaaga ctgcaaaatt
     1681 aaaggaagaa acagctctag tgcctggttt ggtagtgatt ttggttgggg ataatccagc
     1741 cagccaagtc tacgttcgca acaaggagag gtcagctctt gcggctggtt cccgtagcga
     1801 agtagtgcga gttccagaga ccattactca agaggaattg ttagacctga ttgctaaata
     1861 taatcaggat ccagcttggc atgggatttt ggtccagttg ccattaccaa aacatatcga
     1921 tgaagaggcg gttttattag ccattgaccc agaaaaggat gtggatggtt tccatccctt
     1981 aaacatggga cgtctttggt ctggacatcc agtcatgatt ccctcgacac ctgcaggaat
     2041 tatggaaatg tttcatgaat atgggattga cttggaaggt aaaaatgcgg tcgtcatcgg
     2101 tcgttcaaat atcgttggaa aacctatggc tcagcttctt ttggctaaaa atgcgacagt
     2161 aaccttgacc cactcacgaa ctcataatct tgccaaggtg gctgctaaag cagatattct
     2221 tgtagtcgca atcggccgcg ccaagtttgt gactgctgac tttgtcaaac caggtgcggt
     2281 tgtcattgac gttgggatga accgagatga aaatgggaag ctctgtggag atgttgatta
     2341 tgaggcagtt gcaccacttg ctagctatat cacgccagtc cctggaggtg tcggtcctat
     2401 gaccattacc atgctgatgg agcaaactta tcaagcagca cttcggacat tggatagaaa
     2461 ataagagaaa cattcgatta atagagtgta ttttctatag ctatatctaa aatggcagaa
     2521 atgaatatta aattttagat ataagattac aaaaggaggt ctgcgtctcc tttttattgt
     2581 ataataaaag tgagaggaaa aaaggatgaa agtgattaat caaaccttat tagaaaaagt
     2641 tattattgaa cgttctcgtt caagtcataa aggagattat ggtcgtctgc tgctgcttgg
     2701 tggtacttat ccttatggag gtgccatcat catggctgct ttagcagctg taaaaagcgg
     2761 tgcaggattg gtgaccgttg gaacggacag ggaaaatatc ccggctctgc acagccattt
     2821 acctgagcct atggcctttt ctcttcaaga ccagcaattg ttaaaagagc aattggagaa
     2881 ggcagaagtt gtcttgttgg ggcctggttt acgagacgat gcttctggag aaaatctagt
     2941 aaaacaggtc tttgttaatt taagccaaaa tcagattttg attgtagacg gaggtgcctt
     3001 gaccattctt gctaggacaa gtttgtcatt tccctcaagc cagcttatcc taactcctca
     3061 ccaaaaagaa tgggaaaaat tatctggaat tacgattgaa aagcaaaagg aagatgcaac
     3121 ggctagtgtt ctgacttcct tccctcaagg aacaattttg gtggagaaag gcccagctac
     3181 tcgtatttgg gaagttggcc aatctgatta ttaccagtta caggttggtg gtccttatca
     3241 ggcgactggg ggaatgggag atactctggc tgggatgatc gcaggatttg taggccaatt
     3301 ccgacaggcc agtctctacg agcgtgtggc agtagcgacc catcttcatt cagccatagc
     3361 ccaagaacta tctcaggaaa attatgtggt cttaccgacg gaaatcagca ggtatcttcc
     3421 caaaataatg aaaattattt gtcaacaaga gagggtaagc aaagataaac ttgtttaaaa
     3481 tagacagata aatctacttc cttctcttaa tttatgattc ttgaaatgcg cctgctttaa
     3541 ggctaaacta gacgtatcaa agttaagagt ttgtttttgt aactggaaag agatgaacaa
     3601 atcaaataca taaaagataa actcattttt attcgtttgg taaaaataaa atgcatattt
     3661 ttaaagaaag attgatgaaa aatgtagatt tgatgttttt acttgaataa aaagcggttt
     3721 catagtaaaa taagaactga gaatgatgga ggtaaatcgg tggaaaatct gaagaaaatg
     3781 gcaggtatca aggctgctga gttcgtgagc gatggaatgg tcgttggact tggaacaggc
     3841 tcgactgcct attattttgt cgaagaaatc ggtcgtcgta tcaaggaaga aggattgcag
     3901 attacagctg taacaacttc tagtgtgacc actaaacagg cagaaggcct taatatcccg
     3961 ctcaagtcta ttgaccaagt agactttgtc gatgtgacgg ttgatggcgc ggatgaagtg
     4021 gatagtcagt ttaatggaat caaaggcggt ggtggtgccc ttctcatgga aaaggtggtc
     4081 gcaacaccat caaaagaata catttgggtg gtggatgaaa gcaagctggt cgaaaaacta
     4141 ggtgctttta aattgccagt agaagtggtt cagtatggtg cagagcaggt ctttcgtcat
     4201 tttgaacgag ctggctacaa accaagtttc cgtgaaaaag acggccaacg ttttgtgacg
     4261 gatatgcaga attttatcat tgacctcgcc ttggatgtca ttgaaaatcc aattgctttt
     4321 ggacaagaat tggaccatgt cgttggtgtt gtggagcatg gtttattcaa ccaaatggtg
     4381 gataaggtaa tcgttgctgg acgagatgga gttcagattt caacttcaaa aaaaggaaaa
     4441 tagaaggggg cataagatgt ctaaatttaa tcgtattcat ttggtggtac tggattctgt
     4501 aggaatcggt gcagcaccag atgctaataa ctttgtcaat gcaggggttc cagatggagc
     4561 ttctgacaca ctgggacaca tttcaaaaac agttggtttg aatgtcccaa acatggctaa
     4621 aataggtctt ggaaatattc ctcgtgaaac tcctcttaag actgtagcag ctgaaatcaa
     4681 tccaactgga tatgcaacaa aattagagga agtatctctt ggtaaggata ctatgactgg
     4741 acactgggaa atcatgggac tcaacattac tgagcctttc gatactttct ggaacggatt
     4801 cccagaagaa atcctgacaa aaatcgaaga attctcagga cgcaaggtta ttcgtgaagc
     4861 caacaaacct tattcaggaa cggctgttat cgatgatttt ggaccacgtc agatggaaac
     4921 tggagagttg attatctata cttcagctga ccctgttttg cagattgctg cccacgaaga
     4981 cattattcct ttggatgaat tgtaccgtat ctgtgaatac gctcgttcga ttacccttga
     5041 gcgtcctgcc cttcttggtc gcatcattgc tcgcccttat gtaggtgaac caggtaactt
     5101 cactcgtacg gcaaaccgtc gtgacttggc tgtatctcca ttttccccaa ctgttttgga
     5161 taaattgaat gaggctggta tcgatactta tgctgtgggt aaaatcaacg atatctttaa
     5221 cggtgctggt atcaaccatg acatgggtca caacaagtca aatagtcatg gaattgatac
     5281 actattgaag actatgggac ttgctgagtt tgaaaaagga ttctcattca caaacctagt
     5341 tgactttgat gccctttacg gccatcgtcg taatgctcac ggttaccgtg attgtttgca
     5401 tgagtttgat gaacgcttac ctgaaattat cgcagctatg agagagaatg accttctctt
     5461 gattactgcg gaccatggaa atgacccaac gtatgcaggg acggatcaca ctcgggaata
     5521 tattccattg ttggcatata gccctgcctt taaaggaaat ggtctcattc cagtaggaca
     5581 ttttgcagat atttcagcga ctgttgccga taactttggt gtggaaactg ctatgattgg
     5641 ggaaagtttc ttagataaat tggtataaga tgacgcgcta tgctttgctg gtgagaggta
     5701 tcaatgttgg tagtaagaat aaggtcgtta tggcggagct tcgtcaagaa ttgacaaact
     5761 tgggactgga aaaggttgag agctacatca acagtggcaa tattttcttt acttcgatag
     5821 attccaaagc ccaattggtt taaaagctag agactttctt tgcagtccat tatccattta
     5881 ttcagagctt ttctttactg agtctagagg actttgaggc ggaacttgaa aatctaccag
     5941 cttggtggag cagagacttg gcacgaaaag attttctctt ttacactgag ggtttggatg
     6001 tggaccaagt catcgcgaca gttgaaagtt tagagctgaa agatgaagtg ctttatttta
     6061 gaaaacttgg gattttctgg gggaaatttt ctgaagaatc ctattctaag actgcctatc
     6121 ataagtactt gctgaaggtg cctttctacc gccacattac tattcgtaat gctaaaacct
     6181 ttgacaaaat tggtcaaatg ctaaaaaata ataaaggaga cacataatga catttttaaa
     6241 caaaatccat gaaactgcta ctttcctgaa agaaaaggga attgcagccc ctgagttcgg
     6301 tctaatcctt gggtcaggac ttggagaatt ggcagaagaa atcgaaaatc cagttgtagt
     6361 agactatgct gagattccaa actggggccg ttcaacagta gtcggtcatg ctggtaaatt
     6421 ggtatatggt gaactggcag gtcgcaaggt cttggctctt caagggcgtt tccatttcta
     6481 tgaagggaat cctctggaag tggtgacttt cccagttcgt gtgatgaaag ttcttggatg
     6541 tgaaggtgtt attgtaacca atgcagctgg cggtatcgga tttggtcctg gtaccttgat
     6601 ggctatctca gaccatatca acatgacggg gcaaaatcca ttgatgggtg aaaacttgga
     6661 tgactttggc ccacgtttcc cagatatgtc tagggcctac acaccagaat accgtgccac
     6721 tgcccatgaa gtggctaaaa aacttaatat caagcttgat gaaggtgtct atatcggagt
     6781 tactggtccg acttatgaaa caccagcaga aattcgttcc tataagacac tgggagcaga
     6841 tgcagttggt atgtctacgg ttcctgaagt tatcgtggcg gcccactctg gcttgaaagt
     6901 tctgggaatt tcatgtatca ctaactttgc ggccggtttc caagaagaac tcaatcacga
     6961 agaagttgta gaagtgactg aacgtgttaa aggtgatttc aaaggcttgc ttaaagcgat
     7021 tcttgctgaa ttgtaagaaa aaagatttaa aagggggagt gcctctgttt tttcaggatt
     7081 gactgcctat ccggattaaa gaagaaacag aggaatacta tgagcttctt cctgctctta
     7141 taactgaaag aagcggaaga ataggtgtgt ctgatctgat agccagcatt gtgaaagaca
     7201 agattctagg atactagcat tagcttccta gccaagtaga ctagtatgat aaggagagat
     7261 gagaatgaat tgactttctg aatttctcag tcttatcata tatagcacaa tgagatttcg
     7321 cttgagtctg cttgtaaata aacgaaaaga aagataagaa ataatgaaaa ttggtcaacg
     7381 aattatgcgc tttggcataa aaaattaagt atcggagttg tatctgttgt agtcggcttt
     7441 gatttctagc tccagctgga atttcagcca atgaagtaaa gcaagatgta acatctgaag
     7501 tggtaatagg tgtgctagat tctaaggagg aattgaaaga gtcagaaaat gatgctccaa
     7561 aactagaaac tcctcttaga gaggagccaa gactagctcc tcaaacgctt ccggaagcaa
     7621 gtgaagttct tgaaaacaaa agggaagagt caaaagtaga gataatagag ccagctcaag
     7681 cggatgatat ccgcaaggtt gttggggaat tagccaagga tataagtatt actaagttgt
     7741 atatgacagg tcattctctt ggatgttacc tagctcagat tgcagcggtt gaagcttacc
     7801 aaaaatatcc tgatttttat aaccatgtat tgaggaaagt gacaactttc agtgctccta
     7861 aagtgattac ttccagaact gtttgggatg ctaagaatgg tttctgagat gttggtttgg
     7921 aaagtcgtaa attagctgtt agtggaaaaa ttaagcatta tgtggttgat aatgacaatg
     7981 ttgtgactcc cttgattcat aataatcgtg atattgttac atttacaggt aattcacgct
     8041 ttaaacaccg ttctcgtggc tattttgaaa gtccaatgaa tgatattcct aactttaata
     8101 ttggtaaaca agctaccttg gataaacatg gttatcgtga tccgaaattg gataaagtgc
     8161 gattctttaa gaaacaggct ctacctcaat cttctagtca accaagcgct gaaccaatgg
     8221 aaaatattgc cttaggaaaa caggttactc aaagttcgac agctttcgga ggagatgcta
     8281 gaagagctgt ggatggcaaa gtcgatggta actatggtca caattctgtc actcatacaa
     8341 acttccaatc taagccttgg tggcaagtag atttggctaa agaagaaacc attcgccaaa
     8401 tcaatattta caaccgaaca gacactgccc aggatagatt ggcaaacttt gatgtcattc
     8461 ttttagacag ttctggtaaa gaaattgagt gaaaacgtat aatatctcct aaagatgtgt
     8521 cagcacaaat tacgattaac cataaaaaag cgcgctatgt tcggattggg ctagaaggct
     8581 ataatgccct cagtcttgca gaagttgaag ttttccgctt tatagctacg aatgctgaaa
     8641 cggcgacaca agtttctaag ccagttcaac caatcagtca gactcctgtg aaagataaaa
     8701 cattgacaat tcaacacagt ggagcttaca ttgcccgcta ctccataact tgggaagaag
     8761 ttacagtaga taaagatgga aaccaagttg ttcgtagtca ttcttgggaa ggaaacggtc
     8821 gcaaccagac tgcaggtttt gtcctcaacc tcccaatcaa agaaaatatg agaaatctgc
     8881 gagttaagat tgagaaaaag acgggcctac tatggaatag atggcaaaca atctatgaaa
     8941 acagaccaat tttagctcaa ccccaccgta aaattaccca ttggggtacg acattgaatt
     9001 ccaaggtgag tgacgatgat gtcttgtaat ctgatggtac aatgacagtt agtttgtcta
     9061 gtttataaga aagtactacc tgagcttgaa tagaactcag gtagctctct gtgaaagaac
     9121 aaaattaata ctcaatgaaa atcaaagagc aaactaagaa actagccgca ggttgctcaa
     9181 agcactgctt tgaggttgta gataagactg acgaagtcag tcacatatat aatccaaggc
     9241 gacgttgacg tggtttgaag agattttcga agagtataaa cagaaaggta gagcgcgtgt
     9301 tctaatttga acacgagtag aaaacttttc taaaaataaa aacgaaagga tgggtaaact
     9361 gtattcgctg aactgaatac gggcgactct cctctaaatc aaaattaaga aagaaaggaa
     9421 ttgaccccac cctaaaagca gtgggaaaaa gatagttggt ctagcgagca tcgctcactg
     9481 cgcccaactc ctattttccc ttcgcttttt gatgggtttg gtatctttct caatataaaa
     9541 tataaaataa agaaaggtag agcgtgtgtt ttgatttgaa cacgagcgga aaactcggaa
     9601 aatagataat ctgactgaaa aatcaggatt tctcgtcagg ttcctaattt tcagtcgttt
     9661 tcttctcgct ctttgtatca taaattatgt ctatccatat tgctgctcag cagggtgaaa
     9721 ttgctgataa aattcttctt cctggggatc ctcttcgtgc taagtttatt gcggagaatt
     9781 tccttgatga tgctgtttgt tttaacgaag tgcgtaacat gtttggttac actggtactt
     9841 acaagggtca ctgtgtatct gtcatgggaa ctgggatggg aatgccatct atttcgattt
     9901 atgcgcgtga gttaatcgta gactacggtg tgaagaaatt gattcgtgtg ggaactgcag
     9961 gttctttgaa tgaagaggtt catgttcgtg aattagtttt ggcgcaggcg gctgcaacca
    10021 actcaaacat cgttcgtaat gactggccac agtacgattt tccacaaatt gctagctttg
    10081 atttgcttga taaagcctac catatcgcca aaaaacttgg tatgactact cacgttggga
    10141 acgttttgtc atctgatgtc ttttactcaa attactttga aaagaatatc gagcttggta
    10201 aatggggagt caaggctgtg gaaatggaag cagcagctct ttactatctt gctgcccaat
    10261 accatgttga tgcgctagct atcatgacca tctctgatag cttggtcaat ccagacgaag
    10321 acacaactgc agaagaacgt caaaatacct tcactgatat gatgaaggtt ggtttggaaa
    10381 ccttgattgc agaataatta tagccaaaaa ggaagccctt tatgaattgt aggacttcct
    10441 tttcttatcc agaaattgat ctagctctct ctgatttcga agaatagtga ctttatgtga
    10501 atattcttgg caaagttttt ggtaattttc tttttgagtt ttgctacgcc catcccaaag
    10561 aatccatctg ataaactccc agtcaaagcg ttcagggcaa tctgccgcca tactttctct
    10621 gacttttcca cggtatttaa gataacgctt aaaggttcta aagagacagg tcaatggcga
    10681 aaaattgaga aagatgattt ggtcagcttc ttgcattcgt tcttggtagc agcaccaaga
    10741 ataattacca tcgatgaccc aagctttatg cttggtgaga aagtttttta tatcggttaa
    10801 catccattcg tggtcactgt cttgccaacc aggttgaaat tggagtgtgt ccatgtgcag
    10861 ttttggaatg gagtagtagt tagataactt ttctgctaga gttgacttac cagaaccaga
    10921 atatccgata at
//
LOCUS       DAVLBN010000062        10690 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLBN010000062 DAVLBN010000000
VERSION     DAVLBN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.062"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VXC24_001760"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VXC24_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0493839.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VXC24_001761"
     CDS             complement(881..1867)
                     /locus_tag="VXC24_001761"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0493840.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VXC24_001762"
     CDS             complement(1830..2630)
                     /locus_tag="VXC24_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0493841.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VXC24_001763"
     CDS             complement(2880..3260)
                     /locus_tag="VXC24_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0493842.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VXC24_001764"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VXC24_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0493843.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VXC24_001765"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VXC24_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0493844.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VXC24_001766"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VXC24_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0493845.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4813..5988)
                     /locus_tag="VXC24_001767"
     CDS             complement(4813..5988)
                     /locus_tag="VXC24_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493846.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     gene            complement(5992..6579)
                     /locus_tag="VXC24_001768"
     CDS             complement(5992..6579)
                     /locus_tag="VXC24_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493847.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6611..6799)
                     /locus_tag="VXC24_001769"
     CDS             complement(6611..6799)
                     /locus_tag="VXC24_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493848.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            complement(6979..9219)
                     /locus_tag="VXC24_001770"
     CDS             complement(6979..9219)
                     /locus_tag="VXC24_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0493849.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9203..9853)
                     /locus_tag="VXC24_001771"
     CDS             complement(9203..9853)
                     /locus_tag="VXC24_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV0493850.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9921..10490)
                     /locus_tag="VXC24_001772"
     CDS             complement(9921..10490)
                     /locus_tag="VXC24_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0493851.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
BASE COUNT         3119 a         2395 c         1900 g         3276 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agcatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggttgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaaaaga
     2461 tgggcatcgt ctggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtaaaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcata attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattac gaagttttgt atcaaagtca cccttgtcaa
     4201 tagttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttttatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tattttggtt tggttttcga atcaaaaaga
     4741 gagaatcaag ttgattccct ctctatgtta gtttttactt attttcccta cctataggaa
     4801 agctagaatc tattaaaaaa ttcttttttt ctgtgaactt ccccatcttt caataaatag
     4861 aattcccaat agcaaaaaga taatcaggca aggaagtaag accattccca tgctccaatt
     4921 tagatcgaca ttatcaatct gcttaggtaa tcttccagat aaaatctcca ctgaacgcaa
     4981 gtaagtaaag ggaatcagat gtgcaatcct ttgaagaggc tgaattgttt ggatgccaaa
     5041 caataagcca acaatcccaa tgagtgaaag aaagaggaca ggcatttttt gcttgaaaaa
     5101 gtaagcaatc aagtacacaa cttccacaat gacgataaag gctaagaaag ctaagagcaa
     5161 gccaggaaat aatacatctt gtattttccc aatagttact tcttgattca ctaagctata
     5221 aattgggtag ggataatcta actgtccaaa accacttatc agacttccca ctagaaaaga
     5281 aaagccacag attccgataa acagcacagt tacatatccc actccaactc caagagagga
     5341 tattgcaaat gtcacttttg aaacaggata taagtgagct gtgtccagat gattttgata
     5401 tctttctgca aatagttgtg ttagcataaa aataatcgca accacaaaca agcttgggat
     5461 gataacctct aaaatccaga caatctgatc aatcccgtgg gtcggaaact ccaaagtatg
     5521 tgcttttatg ttcaagggat acagggcttg gtaaatcttc cgttcgcggt caacccccat
     5581 ttttaagcca gagctagcag tcgggtcatt tgatacaaat tcataattct tctcttcatc
     5641 tttccactgc agatagtagg cttctttcca gcgcccttct tttagtaaag ttagaatttc
     5701 tgtctttcgc gtcaaaagat ttttttgcac gtctaaatta tttttagcaa actggtattc
     5761 ctccgagctg gtatcagaca tttgggagag tttctcttca ttttcattga tagccctctc
     5821 gttggctgca atgcgacttt ccaacctgct ctccaagctg tgtgagtttg cagtctgact
     5881 atttaaataa aaggtaacac cgagtacaga tacaaataaa gctaagataa tccagtttaa
     5941 acgacttttg aaaacttttt tcaataaaaa tagactaaca tctttcataa actaaacctc
     6001 ttctatctgc ccctgatgaa tggttactac tctatcgcag atatcaacca actcttcctt
     6061 atagtgggaa cttaaaagaa ccagctgttc ttgtctatcg atttgtgcta gcctatcaaa
     6121 aaacttctgt cgataatact cgtctaagcc atttgtaatc tcatccatga gccagcattt
     6181 ggcctgactg agaaaataca tagcaatcac caagcgttgc ttcatcccta aggaatactt
     6241 gcggatggga agactgatat agtcagtcat ttcccagtag gcgatttcat ctctcaagtt
     6301 taggtctgac ttccagatgt tttttatgag acgaaggtag tccatcccac ttaagtttcc
     6361 atccagccat tcaacgctct cataataaaa caaagaagga ggaactgcga tgtgtccact
     6421 actaagggga agcaacttgc tcatagctcg gaatagtgtc gtctttcccg agccattgat
     6481 agcaagaagg ccataaatcc tacccttttt aaaggtaaaa tccgcatctt gcaagatgac
     6541 ttgtcgcgtt tttaaggtaa catgagtaag atttaacata tccagccctc cttttctcac
     6601 tctttaagga ttaataactt ccagtatagt agtttatgac ctcataacga gcgtagttcc
     6661 agcctccgcc aactttatac tcagaatagc tgtaataacg agaccattcc ggaatccaag
     6721 catactgatg gtcgtgatag ttggtactat attccaaaac cgtattccaa tcatacttgt
     6781 aacttttagt gactgtcaca gcagatacac tggactgaag aagaccaata gattataaac
     6841 taactaacta aaacaacttt tgctgatttt taatgatttt atatcctcaa tattgaatac
     6901 gttttcatta tgccgttttt atcattatta tgcaacaaat ttttagttta tttcactaat
     6961 ctacaacatt tatccttcct atcgaacact ttcgattttc caactatcca accccttaaa
     7021 acgtatagct ccttgctggt cagttcgata aactttgcta ttgatacctt ccagtcgtgt
     7081 caatgtttcc tgatggggga gtttcattcg attgctcttt ccaactgaga taagagtaag
     7141 ctctggtttg agtttttcta gaaaggctgg acttgatgat tttttattgc catgttggct
     7201 agctttcaaa acatttactt tcaagtctgg atagtgcttc agcaagtcct tctctccttt
     7261 ctcctccaaa tttcccgtga agagaaattg cttatccaag aatttcccat acagaactag
     7321 ggtatcatcg tgtcctccat ctcccatttt ccttggagat agaacttcta actgacttcc
     7381 aaaaatgggc aagttctccc ctactatcat actacgcacc tttgtttgag tcgcctgtag
     7441 ttctgccaca aattccttct gtttcagact gtcttttgat actagaatct cccctacatg
     7501 gaaagccttg gtcatctctg acaaatctcc aacatgctcc ttgtccgtgt tagtcaaaat
     7561 tagctggtca atcttagcta ctcctcgact tttgagatag ggtatcaagc ttcgctgggc
     7621 attgctggtc gtcatctttt cttgccattt tttgattttc ttataagatt ctgccttacc
     7681 acctacatct atgagaatgg ttttcccagt tacatcccgt aggaaaatac tttctccttg
     7741 ccccacatcc agcatggtga tttcattttc cagtggatgc ttggtcagga gaaagagccc
     7801 tgtaatcaat aagcacaata ccgttagctt tttaatgttt ttcctcaaat catagaccaa
     7861 agccaaagaa attaacaata ggattaaaag ccattcattg ggttgtccaa agacaagcgg
     7921 tctacttgcc acctgcgaga ccaagcgaat aatgccctct aaccattcaa agataaagtt
     7981 cagctgaatg actggataga gaaaggaaag gacaaataag atagacaaga gcggtaagaa
     8041 gaccaagtca aaaagaaagg aaaagacaaa ggtcaaaagg atagaccaag gttgaaattc
     8101 cgcaaaatag aaggatagaa tgggcaatat gcccaaggag atgactagac tttcactagt
     8161 aacagccttg agcccctccc cttctttgct ggtcatggtc aggataaaag cataagcaca
     8221 ggacaagact cctcctgctg tcaagaaaaa gtttggcatg acaataaaga ggacaagcac
     8281 cgtcaaggca aaattatcca agcccttaac cccatgttga gccagtagct tttgcaagag
     8341 actgcgaata accgatgctg aaaatccagt tagtcccgca tagataaggg aaaagggata
     8401 agtcagccac ttcaactttt cttgtgtcaa gcccaatcgt aaaagtagtt tcttaaatcc
     8461 gtccatgaaa aaccctacct gcatacctga caaggcaaaa aggtgaataa ttcctaaact
     8521 ggaataaagc tcattcatct cctcaaaatc ggtgtccaga tgtcctagca agagtcctgt
     8581 catgtaattg cgcatagggt ctgggaagtg catcttaatc caaaccacag cctttcgacg
     8641 taaactggac aggttttcac ctatatccca actgccaacc ttttggagtg actggattct
     8701 tttaatattg agtgtctggt aaattccctg agtcttcaga tagccttggt agtcaaagcc
     8761 accaaaattt ctctgccctt ctggctccga aagcttccct tctagtccta tctcatgaag
     8821 gtcagttaaa gcttgaaagg cttctttctc ctcctcggac tggagtttat aatagacttg
     8881 gaaagcacga ccatcagact taccacgaaa ggacagactg tcaccgttaa ccttaatagt
     8941 gtctggtaaa atccgtaccc tttcaacaga atccaccaaa ttttgactca cttgactctg
     9001 ttgccaagtt tgaaacagaa accagaagcc aaagactcca caaatcacta gaactttacc
     9061 tgctgatttc caaggaaatt ggataaagag gcagactagc agaaaaacaa aacccaacaa
     9121 agcaaaatag gatactgaga aaatggcgta gtaaagccat agtaacagaa aactcaggta
     9181 aattagggga atagagaaat tcttaatcca ctgtaacata gtctttaagt ttttctatgg
     9241 tcttggcacc aatgccagag accttcttga gctcgtctac tgacttgaac ttgccatttg
     9301 cctcacgatg gtcaataatg tcctgagctc gttttcctcc cagtcccttg acctgcttga
     9361 gttcttccag actggccttg ttgagattga ccttcttttc cttgcttgtt gaagaagctg
     9421 tccccgaacc agtctgttga ctaactgctt cttctccctt agtaggaacg taaaccagag
     9481 cctcatcact aactttctga gctagattga gcgacttgct gtctgcttgc tctgtcaagc
     9541 caccagcctt ctgaacagca tcattgactc gactacctac aggcaagtca taaatccctg
     9601 gcgatttgac agcacctttg acatctactg tgattagatc ttgttcaact ggttcttcct
     9661 tctcttcctt gttcacttcc tttccggtcg atgagtcctt ggaaacagct gcaacttcag
     9721 cctgcaaatt cgtctctttg acagatgttt gtggagctgg ctttagcagg aaaaatcctc
     9781 ctacaagcaa gcccagacca gtacagatga cgatgatttt atactctttg attttctcga
     9841 taattgcttc catattttct cctctcttag attattcgta agaggaagaa aaaacagtcg
     9901 aaaaatttct tttcaactgc ttatttattt gcaaaatagt cttccttggt caagacataa
     9961 tgaactcttg tcacgattcg gcctttttca tgctggtcca tacaagcata tggttctgca
    10021 tgggaaaaac gcatgcctga tttctccatg acctttcctg acgcgggatt agccttatcg
    10081 tgaagggcag tcaacttatt catccctatc ttctcaaaag ctagctcaat cacagcacga
    10141 ttggcttctg tcgttaatcc ttgattccaa tactttttat tgataatgta gccaatagct
    10201 gccttcttaa gaacaggatc aatcttgtgt aagtcaatag ttccgataaa cttgccgtta
    10261 tcttttaatt caatccccca acgtcccaag ggattagcca agtagaactg agcaatgtta
    10321 ttcttggttt cttccaagct ttgattggtt ggaaaagtgt aacgtgtatt acccttgtcc
    10381 gaggcatagt caaacattgc ttccgcatca tccaaagtta caggtctaag caataaacgc
    10441 tccgtttcta tagacggata ctgggcaaat ttcacaaata ttgattccat acttttccct
    10501 ccattagagc ttgattttca ctagtctagc ataaaaaaat ttggatgaca agtttttctt
    10561 gatttttgaa gcggtttcat atacaatgaa accgtcacat ttttgattta tgaactggaa
    10621 tgtgacaacc aaaacaagac cgtcaattga aaggtaggtt atctcaatgt taatcggaat
    10681 cccaaaagaa
//
LOCUS       DAVLBN010000063        10620 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLBN010000063 DAVLBN010000000
VERSION     DAVLBN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.063"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            44..772
                     /locus_tag="VXC24_001773"
     CDS             44..772
                     /locus_tag="VXC24_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0493852.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1231..1425
                     /locus_tag="VXC24_001774"
     CDS             1231..1425
                     /locus_tag="VXC24_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0493853.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(1791..3101)
                     /locus_tag="VXC24_001775"
     CDS             complement(1791..3101)
                     /locus_tag="VXC24_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0493854.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            3338..4210
                     /locus_tag="VXC24_001776"
     CDS             3338..4210
                     /locus_tag="VXC24_001776"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0493855.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            4341..5172
                     /locus_tag="VXC24_001777"
                     /pseudo
     CDS             4341..5172
                     /locus_tag="VXC24_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5283..6209
                     /locus_tag="VXC24_001778"
     CDS             5283..6209
                     /locus_tag="VXC24_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0493856.1"
                     /translation="MDLSQTMPSYAQVVSLYDDTSISVSNNETDKVLAGSLYTDTNEQ
                     GLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQFQTKIVRVINDE
                     DDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQKNKKYTVLS
                     QQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQ
                     NRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLG
                     TLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            6386..7393
                     /gene="gap"
                     /locus_tag="VXC24_001779"
     CDS             6386..7393
                     /gene="gap"
                     /locus_tag="VXC24_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0493857.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(7460..8296)
                     /locus_tag="VXC24_001780"
     CDS             complement(7460..8296)
                     /locus_tag="VXC24_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0493858.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            8422..10617
                     /locus_tag="VXC24_001781"
     CDS             8422..10617
                     /locus_tag="VXC24_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0493859.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT         3314 a         1832 c         2263 g         3211 t
ORIGIN      
        1 ttgttatact actattagaa tattatagag agaaccagat taaatgagta caaaatattt
       61 atttatttac aatgagattc gtgaaaagat tctttgtaat aaatatacca tgaacgaaca
      121 attgcctgat gaaatgacat tagctaaaca gtttgcctgt agtcgaatga cgatcaaaaa
      181 agctttagac ttgttagttt ctgagggctt aatttttaga aaacgtgggc agggaacctt
      241 tgttctctct cgtggcagct caaaaagaaa attaatcgtt ccagaaagag atatccgggg
      301 actgacaaaa atatctgaag atgctcattc tacaattgac tcgaggatta ttcacttcaa
      361 attagaattt gcaaatgaat ttttagcaga aaaactacag gtcgctttgc agagtccagt
      421 ttataatatt taccgtctgc gtattattga cggtaaacct tatgttctgg aacaaactta
      481 tatgagtact gatgttattc caggtattac tgaagatatt ttacaaaaat cgatttacaa
      541 ttacattgaa ggaaagttag gattgcatat tgccagtgct acaaaaatct tgcgagcttc
      601 ttctagttca gaaaatgagc aacattactt gcagctcctt ccaacggaac cggtatttga
      661 agtagaacaa gtggcttatt tggataacgg aactccgttt gagtactcga ttagtcgtca
      721 tcgctatgat ttatttgaat ttaattcttt tgcattacga cattcctcct aggagaaaat
      781 gtgaaaatga agccaatctt ttacagactc tagtttaaga aaaatttaaa acagggcaag
      841 aaggtcccat ctatgcttaa atggtttctc ttttctaaat aagatggctt taaaagagtg
      901 atcgttttat ccatcatgtt gaaaaatatc ttcgtatagc ttatagagta ggtactgaaa
      961 ttgttcacct gatctacttc ttatagttat ttagttttaa atagtgtttc aaatattctt
     1021 acactgacga gaagtttttg agtcttttct tgtaacacat atagtatact gatgttagaa
     1081 tagtagactg tgacttctaa caaattgcta gaaatgaatt tcaatctccc aatttatttg
     1141 ttcatatctt cttttaatat attaaataaa ttctgaatca taatcattta aaaaaatttt
     1201 attttttatt tttcattacg aataatatag atgaagggga aagagtatga aaacagaacg
     1261 gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat ttcgtatagg
     1321 gtggatcatc gtatattgtt tgataatatt tcttttgata cttcgagttc aggcgtgaca
     1381 ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtagat tgaaactaga
     1441 atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc tgatctattt
     1501 gtcctgttct tatttcattt cactacatct caaattgagt atgacgaagt gcgctcccat
     1561 gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga taaagactat
     1621 tgggatgaat ttttaaagtt gaactaatta tttttacagg atgaggttta cagcagagag
     1681 tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt tccacttaat
     1741 tttgtgtcta ctttattata ccaagtccac ccttaagtta gataatgaat ctaacttaag
     1801 gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct gatagggaca
     1861 cccagaataa tttgcttttt gaaggcaaga ccgcgttcct ctatattggg aagtgagagt
     1921 tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc gccaataacg
     1981 gtggctgttg tgagtaagtg aatatcaatc tgaggatttt gagcactgat gatagcaatg
     2041 atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga catcactccg
     2101 gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggttgttgt catgaggtgc
     2161 cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct catgccgcag
     2221 agcatgataa ttgtagccca gggaacctta gctaaaatgg cttcttgctt ccctaatttg
     2281 agctttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa tgttttttga
     2341 taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa aagccaaacc
     2401 aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt
     2461 ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact gtaacaggat
     2521 aataaaagca agacgatgag tgggtagata atgctgacga taaagatatg attgccaagt
     2581 gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac aatgcctgag
     2641 ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg agctccaatc
     2701 aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta gaggacagca aacggccata
     2761 gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta taaaatcatg
     2821 tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga
     2881 gtaccgttag ttgttgcaac gttataaaag agagagacgc taaaaatggt aaaaaagagt
     2941 gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt ggttgcgatg
     3001 aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta accaattcca
     3061 atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc ctttcagtta
     3121 gaatatggaa ataggttggc aattttggcg ctcaaaagac cacctgtttc ctattggtac
     3181 ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac acttgttaga
     3241 attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagta attgcctcta
     3301 gtgcttacaa gtgatattaa aaatagagga cttagtgatg tcaatcattt caactgattt
     3361 aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg ttcattccga
     3421 agattacagt accaatgcca tttttgatca tcatggccaa gctaaggtgt cgctttttgc
     3481 caaggaagct ggtgttttag cggggctaac cgtttttcaa agggttttta ccctatttga
     3541 tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt tgactagtgg
     3601 cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg aacgcgttgc
     3661 cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt atgtagaagc
     3721 cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta atttacgtct
     3781 ttttgagaaa tatgccgtga gagttggcgg tggctataat catcgcttta atttatcaga
     3841 tgctatcatg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa aggcaattgc
     3901 tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc
     3961 tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata atatgtcatt
     4021 ggaacagatt gaacaggcca ttaccctaat tgcaggacgt tctcggattg aatgttctgg
     4081 aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt acgtctccag
     4141 tggtagttta acccatagtg ctaagagtct tgatttttcc atgaaggggt taacctacct
     4201 tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtctttcctc tagaacgagt
     4261 tttatgtcag atagtttaaa cgcctcttca aatatagtaa aatgaaccaa aaatagtaca
     4321 caatgtggta taatcttttt atggcatatt caatagattt tcgtaaaaaa gttctctctt
     4381 attgtgagcg aacaggtagt ataacagaag catcacacgt tttccaaatc tcacgtaata
     4441 ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtaaaag
     4501 gaacaaaacc aagaaaggtt gatagagata gacttaaaaa ctatcttact gacaatccag
     4561 acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg
     4621 cactcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga acaagaccca
     4681 gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctatc acctgtttag
     4741 attgatgaaa caggatttga tacttatttt tatcgagaat atggtcgctc tttaaaaggt
     4801 cagttaagaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tgaatggtga
     4861 gttaatcgct ccaatgactt acgaagagac gatgacgagc gacttttttg aagcatggtt
     4921 tcagaagttt ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag
     4981 attccataga atgggtaagt tagaactctt gtgtgaagag tttgggcata aacttttacc
     5041 tcttcctccc tactcacctg agtacaatct attgagaaaa catgggctca tatcaaaaag
     5101 cacctcaaaa aggtattacc aagttgcaat accttttacg aggctttttt atcctgctct
     5161 tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa atatttggag
     5221 agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaaa gatgggcaag
     5281 aaatggatct gagtcaaacg atgccttctt atgctcaagt agtgagtctt tatgatgata
     5341 caagtatctc tgttagtaat aatgagacgg acaaagtgtt ggctggctcc ctctatactg
     5401 atacaaatga acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga
     5461 caggaaaaaa tttgacagct aatgatctta ttggcaaatc agtctcagcc agcattgtag
     5521 aaagtgctgc cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca
     5581 atgatgaaga tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga
     5641 ttttgaaaga ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc
     5701 catcacagac aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgcttt
     5761 ctcaacagag agttcttgat attgtgatta cctttattcg tgttattcag ggattattga
     5821 ttgtgctttc atcacaagct attgtggtag cagcggttat gattggtatc attatttaca
     5881 tcaatatcat gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt tatcagaatc
     5941 gtggtgtcaa aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc
     6001 tggcattttt ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt
     6061 acccatccat cactaaggtt tttgaattaa atcttttatc tgttttagga actctagttt
     6121 tcgctctatt acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg
     6181 atcctgtaga atcgttacgc tatgaataat aagggattcc ttgatttaca gtcttaaaaa
     6241 gaaactcaca tagaaaaaca atggccatac ttgcaattca actcaaatag ttgtataata
     6301 ggtttgttga aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat
     6361 gattttcata aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg
     6421 tatcggtcgt cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat
     6481 caacgacctt acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg
     6541 tcgtttcgac ggtactgttg aagttaaaga aggtggattc gaagttaacg gtaaattcgt
     6601 taaagtttct gctgaacgtg atccagagca aatcgactgg gctactgacg gtgtagaaat
     6661 cgttcttgaa gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg
     6721 tggagctaaa aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt
     6781 caacactaac cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac
     6841 tacaaactgc ttggctccaa tggctaaagc tcttcaagat aactttggtg ttgttgaagg
     6901 attgatgact actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg
     6961 tggtggtgac cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg
     7021 tgctgctaaa gctatcggtc ttgtaatccc agaattgaac ggtaaacttg acggatctgc
     7081 acaacgcgtt ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa
     7141 cgttactgtt gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta
     7201 cacagaagat ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga
     7261 cgcaactcaa actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg
     7321 gtacgacaac gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa
     7381 aattgctaaa taattcttga gttgatagaa agcaaggctt tgtggtcttg ctttttatat
     7441 ggaaaaatgg atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa
     7501 gggtagtgaa agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat
     7561 gaagcataag ccggcttgtc tttgatttac tattatagag agggtctccc aggataggaa
     7621 gattatgatg cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaat
     7681 gagccaagga agtcttgttt gagaattgct ttaatctgct tacatgcgtt tcagcatatt
     7741 gcccattttt tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt
     7801 ctctgaaaac aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag
     7861 aaatctcttt tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa
     7921 agagaactaa gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa
     7981 cataggtact gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca
     8041 tcccctctgg tttgtttaca ataatcaagt gttgatcttg ataaacttcc tgcactaagt
     8101 ctgggttgcc ccaagggatc gtcttttggg aataatcttc ctcgtcaaaa gtcaactggc
     8161 aaacatctcc aggatttacg atttccttcc agtggacttc ttcttgattt atcaaaatat
     8221 gtttcttgat tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta
     8281 attgctttac tgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga
     8341 tattgtaaca aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga
     8401 tgaagatgat aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt
     8461 tttaaaaaag aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt
     8521 agtgatcgaa aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat
     8581 ctaacaaaga ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg
     8641 tttgctgtag ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa aactcggact
     8701 cttatttttg accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat
     8761 gttgagctga ctgacatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt
     8821 tctttctata aaaatgacgg gattaactat ggccgttttt tcttggctat tgtcactgct
     8881 ggacgttcag gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatcg
     8941 caggatcaaa ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa
     9001 aaatatagta aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt
     9061 gtgtggggtg tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt
     9121 ctggatcaag ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg
     9181 aattccgtag aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca
     9241 ggatatattg ataaaaacca agaaaccgaa gctgctgaag ttgatatgac ttcgcaattg
     9301 cacgataagt atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg
     9361 gttaatgaag ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac
     9421 cgcatttaca cagagctgga ccaaaactac caagcaaata tgcagattgt ttatgaaaac
     9481 acatcgctat ttccgagggc agaggatgga acgtttgctc aatcaggaag tgtagctctc
     9541 gaaccgaaaa cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact
     9601 ggattccgga atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag
     9661 cctttagttg tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat
     9721 aaccatacca tgcagtatga cagctataag gttgataact atgcagggat caaaacgagt
     9781 cgagaagttc ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccact
     9841 gttaatgatt tgggtgtcga taaggctttt gaggcaggcg aaaaattcgg actcaacatg
     9901 gaaaaggtcg accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt
     9961 caaatggctc aagcatacgc tgcctttgca aatgaaggtt taatgcctga agctcatttt
    10021 attagtagaa ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa ttcacaaaaa
    10081 cgggtgattg ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc
    10141 aacggtaccg gtattagttc atcgcctgca gactatatta tggcagggaa aactggaaca
    10201 actgaagcag ttttcaatcc ggagtacaca agtgaccagt gggtaattgg ttatactccg
    10261 gatgtagtga ttagccactg gcttggcttt ccgaccactg atgaaaatca ctatctagct
    10321 ggctctactt caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct
    10381 tatacgccag gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca
    10441 gccaatacaa aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct
    10501 gatattcgag ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg
    10561 aagattaagg aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat
//
LOCUS       DAVLBN010000064        10559 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLBN010000064 DAVLBN010000000
VERSION     DAVLBN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.064"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(77..1501)
                     /locus_tag="VXC24_001782"
     CDS             complement(77..1501)
                     /locus_tag="VXC24_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0493860.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2046..4325)
                     /gene="pulA"
                     /locus_tag="VXC24_001783"
     CDS             complement(2046..4325)
                     /gene="pulA"
                     /locus_tag="VXC24_001783"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0493861.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4437..6395)
                     /gene="ligA"
                     /locus_tag="VXC24_001784"
     CDS             complement(4437..6395)
                     /gene="ligA"
                     /locus_tag="VXC24_001784"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0493862.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6488..7666)
                     /locus_tag="VXC24_001785"
     CDS             complement(6488..7666)
                     /locus_tag="VXC24_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0493863.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7746..8609)
                     /locus_tag="VXC24_001786"
     CDS             complement(7746..8609)
                     /locus_tag="VXC24_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0493864.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8612..10513)
                     /locus_tag="VXC24_001787"
     CDS             complement(8612..10513)
                     /locus_tag="VXC24_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0493865.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3166 a         2336 c         1893 g         3164 t
ORIGIN      
        1 tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat
       61 ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt
      121 caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga
      181 aattatctgg accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt
      241 cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt
      301 cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa
      361 caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca
      421 ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt
      481 gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa
      541 tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag
      601 tagctaattt ctctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt
      661 gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat
      721 cttctagtac aagagctgca tctttcccac caagttccaa catgatagga cgcataccag
      781 ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt
      841 ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa
      901 cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac
      961 cttgtgttgg tggcttaaac atgaccacat tccctgcaat caaggcaggt gcaattttag
     1021 aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata ccaactggtt
     1081 cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca ccttccattg
     1141 cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca
     1201 ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa
     1261 tttcttcctt atcgcgttct aaaatagctg ctgttttatg taaataagcc gcacgttcaa
     1321 ctgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag
     1381 cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa
     1441 tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga tatcttgtca
     1501 aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag aaaatcacaa
     1561 ccctttttgc aaaatttttg agattatttt cacaaacttg atttttcaaa gtatactcaa
     1621 taaaaataaa aaaaatccac tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg
     1681 aagagcgtga atgagtatca tctatagtaa aataaaaaaa ctgaacaatt tggttgggga
     1741 cagccaaacc aatttctcac aatgtttcag aaacaagggt gtgctactcc aatttcagcc
     1801 tactataact gtcatagatt gctgaaacaa agtctaggta aaagtcttca taataaaaag
     1861 acctcctatc aagtgttcaa aaactttgat aggaggtctt gttttgtgaa aatatttatc
     1921 aaattttcta tacaagtgag ctgttagcca ggttctttct attctttcaa tttcaatgaa
     1981 tggatttttt actaatactc ataactggga atttgtctgt gtaaaaatag cgagatagat
     2041 ggtatttata aaacactcaa gacagctaga ctaatatcat ttaaaacatt atcttctttt
     2101 gagcgactgt tggttaccaa catagctaaa tttcctgcat tttcaaattg atagggttct
     2161 gatttagcat tcacaaccac caagaggtgt tctttgccgt gaacttcata gataaggtag
     2221 ccgctatgtt caatcgcaga atgcacaaag acatgatggt aaatttcatc atagctagag
     2281 taagaaaagg caccagtttt tgtcttcaat cggatgactt gacggataaa ctcaatactg
     2341 tcttgacgct cattaatcaa gttccagttc acttggttca cactgtcagg agcattatag
     2401 ctattcatcg cacgctctct atcatcatgg gtcaactcac cattttcacc agtcgcaacc
     2461 agtttggtac gaccaaattc ttgaccgatt tccataaagg ccatcccctg catgagcaga
     2521 ttcatggctg tggcagtttc gaccttgcgc atgatttgct ctgaactttg gtctggatga
     2581 agggttgcca ataaatcgtg aagattgtaa ttgtcatggg cttctacata gttaagcacc
     2641 tgatttggat gtgtatagct tcctaattca cgacttccta ggattgcttt agctagaatt
     2701 ggctctgtcg cagcaccact gacaaaacct gacttgatag caccataaac ttctccccct
     2761 ttgacagcat cgcgctgatt gtcattaaag aaaccaatat ttggcatctg gtaggcattg
     2821 tccttcttgg ccttatcata aggggcaaga cctgttccca tatcccatcc ttctccatag
     2881 aggataatgt tggagtcgat ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca
     2941 tcatgaatcc ccatcaagtc aaaacggaag ccgtcaatat tatattcctg cacccagtat
     3001 agaagagaat caatcatata cttgcgaaac atttcgtgtt cactggctgt ttcatttcca
     3061 acacccgttc cattctggaa ggtaccatat ggattcatac gataatagta atcagggact
     3121 gttgtttgga atggtgcatc aacaactgag aaggtatggt tatagactac atccataatg
     3181 actccaatac ccgcatcgtg ataagcttga accatcacct tcaaatcacg aatgacctga
     3241 gctggatcat ctggattagt tgaaaaacta gtttctggcg cgttatagtt ttgtggatca
     3301 taaccccagt tgtaggttac atttccatcc tcatcgtatt ctttatgacg gtctgcaatt
     3361 ggttgcaatt gaacataatt gtagcccagc ttcttgatgt aatcaaaagc agttgactgg
     3421 ccgtattggt taactgttcc agcctgagca gcacccaaga aagttcctcg aagatgttca
     3481 tctacacccg atgtaggtga tttagtcaaa tcacgaatat gcatttcaca gataactgcc
     3541 ttacatggat tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc gaagttttca
     3601 acttgctttt ctacatggct cagaatagct gaacgtttgc catcagggct ggtcgcgatt
     3661 gtataaggat cacgtgtcag tgtttggtga tgagggaatt ggacttgata ctgataagcc
     3721 ttacctacca aatcttcctc aacatccaaa ctccagacac cgattgtatt gtccttatga
     3781 ttataagagt agctattgcc tcttttcatc tcaaaagtct tccaaacggg tgcatcatta
     3841 gcagctgatt cataaacgac aacttgcact tctgtcgctg taggtgacca gagggaaaaa
     3901 tgagcctgat tgtcctctac acggcaaccc aattctcctt ggtaacccca atgatggtca
     3961 aaactagcac tgttaatggc cttatcaaag gcaaaaggat tttgattttt atagaaagga
     4021 ctggcaatag caggattttc agagtaataa atcctatcat cgccttccaa aatccagacc
     4081 tctgttaata ggggatagtg attaaaacgg atagaatatt ctttactagt ttgacctgta
     4141 tgaaccacaa aattcaagct ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa
     4201 gctccaaaat aatcttcttt gtaggttagc aaatcaattc gttgatcctg actttttaca
     4261 aaggagcaag tgtcatattc tccattctta cgatggtaat gaatgcgcat agggtagtta
     4321 tacatttttt atttttcctt tttactttgt ttctatttca ctaataaatt tttgtcaatc
     4381 tcgtctcaat taacagacat agtcatattc tctaaactct gtttttaaac gatccattac
     4441 aaactttcta gccatgcctc atctctgacc tggataccaa gttcttgtgc tttttgcagt
     4501 ttacttccag cgtctgcacc taccacgacg aggtcggtct ttttagaaac actacctgtc
     4561 actttggcac ccagactttc gagtttactt ttagcttctg agcgcttgag tcgttccaat
     4621 tttcctgtca ataccacggt caaacctgac aaggccgcat ccgctactac cgtctgtcct
     4681 ttatagtcca gattgacccc agtttctttc aattctctga gcagaatttc agagccttct
     4741 gtcgcaaaat aagtctgaag acttttggca atcacgccac ctagactttc aatactagcc
     4801 acttcctctg aatctgcctg atacagattt tcaattgaat ggaaatattg aagtaaaagc
     4861 tgactagcct tgcttccgac atgacgaatt cccaaaccaa ataagagctt ctcggcagaa
     4921 ttttcctttg atgcttggat agcctgatac agtttagcag cggacttttc cttaaccccc
     4981 tctaaaagga ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc cttgactaaa
     5041 ttagcagcaa aaagcttctc aacaatagat ggaccaaggc ctgtaatatt catagcatca
     5101 cgagaagcaa agtgaatcaa gccttccatg atttgagcag ggcaacgcgg attgatacaa
     5161 cgtagggcca cttcatcttc aaagtgcaac aagtcagagt tacaacttgg acagtttgta
     5221 gggatatcta gtttttcttc agaaacccgt ttggactcta ccacacgtaa aacggcaggg
     5281 atgatgtcac cagccttata tacaatgacc gtatcgtctt ttcggatatc tttttcagca
     5341 atataatcta cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt
     5401 gttagattag cagttggagt tacaacaccg gtacggccaa ctgtccagtc aactgataag
     5461 agttgagctt ctttttcttc agcagggaac ttgtaggcta ctgcccactt tggagcctta
     5521 acggtaaaac caagttcttc ttgacttgct aggtcgttga ccttgattac cactccatca
     5581 atatcgtaag gcagatttcc ccgttcctgt cctacttctt ggataaaatt ccagatttca
     5641 tctatgtttt cagccaagat tcgcttagga ttgaccacaa aacctagttg ttctaggtac
     5701 ttcaaaccct tttcttggct atcacgagtt gaagggctgg cttcttgata gagaaacgtt
     5761 gcaagattac gcttggcaac tactgctgta tccaactgac gcagagttcc tgctgccgca
     5821 ttacgaggat tagcaaattc aggctctcca ttttcttggc gcacttggtt aacttggtca
     5881 aaggaagcgc gtggcatgta acattcccca cgaactgtga tatctagttc ttctggcaaa
     5941 gtcaaaggga tgtccttaac acgcttgagg ttttctgtga tattttcacc aattgaacca
     6001 tctccacgtg ttaccccagc aaccaaaatc cccttttcat aagtcagcga gatagataag
     6061 ccatcgattt tcagctcaca aatataggtc ggatgagcca cttccttacg aacacgcgca
     6121 tcaaaagcat ctagctcctc acgtgaaaaa gcatcctgca aactataaag aggatactga
     6181 tgactgtatt tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt cggactgtct
     6241 gctagcactt gctctggata agcagtttct aactcgacca actcacggta aaggcggtca
     6301 tactcactgt ctgaaaccga gggattatcg ctggtatagt actcagtcgc atagcgattg
     6361 agcaaagcga ctaactcatt cattctttta ttcataagac cattttacca taaaacaagc
     6421 cctcctcaca aacgagaagg gcggaaaaaa cacttagttt gaaattattt ttgaaactca
     6481 agcaacctta tatcaatttt tcaaaatgag ttcgaacata aataaacgat atacaagaca
     6541 agatgataac accacttcca attatcagga aagaagagag atgtatactt ggcaagactg
     6601 tcataaatcc ttttgcaata ggcataaata gaatagctaa ggtaaaaatt gtactcagta
     6661 ctcttccaag aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa
     6721 aaatcgtcat aaacaattca caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg
     6781 gtaatcccat cataaaaact ccgacacctg tcaaagccag taaaatcaaa agattataaa
     6841 tattagcttt aattttacta gctagaagag ccccaatgat gaaaccaata gcccccatag
     6901 ttaaaatact tgcataggct ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa
     6961 attcaaaagc tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg aagaaaattt
     7021 cttgctgatg ccagatatag tgtaacccat ccttgatatc tacaaaaata tctctcccag
     7081 taaaagcctt tttctcttga acttttgctt cctcttttgg aaggaaagcc actagaacaa
     7141 aagcaatgaa aaaagtcagc gagtctagca gtagcgtcat atggagactt gcaaactgta
     7201 aaacaaggaa ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc agctctaagc
     7261 gagaattata gatcacaatc tcatctttct ccaccacttc agttatgata gctttattgg
     7321 ctgtgcgaga aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa
     7381 tcatccagct atcattcctt atgaaagaaa tagccagaca aagaatccca caaacaagat
     7441 ctgccgtcat taaaatctta cgacgagaaa aacggtctga aataactccg ccaaagggat
     7501 tgacgagaat agatgtgacg agctcagaaa tctgatacat tcctaaaact gtctgtccta
     7561 tagtccccat agaagccaac cagacactat ttccataatc atagagcata tttcccattt
     7621 tattgatagc cccacggcta atcaactgca ctgcatagcg attcatatta aagctcctct
     7681 caaattttga aactattgta tcaaaaccga aaggagcttt ttattttttc ccttatttgg
     7741 gaaaattaac ttttgacaaa tttttcgtag tgttcctgat aataggctac ttgctctgga
     7801 agacctaaca catcaaaaat atgtatggcc tcttgcatct gcttacagcc ttctttacac
     7861 tgtccttttt gatataaggc aaaacctttt aaataatgga aaacattacg ctcataaagc
     7921 ttaatacctt tgtcaataat cttctctgta taagcctcaa aatagttggc attataaaaa
     7981 gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca aaatcaaaac taatctctta
     8041 tggcgactaa tctcttggta aaattcctcc ctctccataa cttctctacc aatccgagtg
     8101 acatagtcta catcgtagaa actatagagg ttaccgaaaa gaatcaactc atacatggtc
     8161 cattcttctg ttttgaagaa ataatctgct accttatcca aatcatcctg cttcatatca
     8221 taactcgcat ctctttgaca aatcagacct tgtagcaaaa tccagttcag ctcaaaataa
     8281 aggggagtcg tcgaactctt agacttttca agttgttctc tttgaagctt ttgaaaacct
     8341 gcaatatcgt ttgaatagta aagtgggata atctgtgcca tcatagacac atgttcatga
     8401 ttatgaaaat tccttgcctt atccatgaaa ttttcgattg ttacatgaat gttatccaaa
     8461 atctcaaaga aacgggagac tgccaggtca gactccccaa gctcaaagcg agataactga
     8521 gaggtagagc aggattcgcc tgctgcttcc tttaaagaat aatttccact tgttcgaaat
     8581 tcacgaaata cttttccaag atgttccatc tttacacctg atctgataat tcttcccact
     8641 caagcatagc ttcttcctga cgatggctga ttttgtccag ctcagcctgt aattccatga
     8701 gtttgtcggc atcgtttgtt tccaacattt gttcagaaat ggcttggctt tgactttcta
     8761 gctcttcaat ttcagcttct agactttcga tttgtcgcat gagtttgcga acttcttttt
     8821 gactttcttt ctgggcctga tagtcattga ctggacttgc ttcctttgct tgattgctag
     8881 ttgaagcttc ctcagtctga ctcatttctg ctgttgctct cttctcaata tagtagtcgt
     8941 aatctccaag gtagagagtt gaaccattct cagacaattc caaaacatga gttgccacac
     9001 gattgataaa gtaacgatca tgactgacaa aaagcaaggt accatcaaag tcaatcaagg
     9061 cattttctag cacttcctta ctatcaatat ccaagtggtt ggtcggctca tccagaatca
     9121 aaaagttatt gttttccata gacaatttag ctaaaagcaa acgagctttt tcgccaccag
     9181 atagcatgcc gactgatttt ttaacatcat ctcctgagaa aaggaaggct ccaagacggt
     9241 tgcggatttc aacttctggt gtcagtttga aatcattcca gagttcatcc agcaccgtat
     9301 tacttggtgt cagcttgctt tgggtttggt catagtaacc aacctcaaca ttagcgccaa
     9361 agcgcttttc tcccttgata aaaggaatct ggtccacaat agacttgata aaggttgact
     9421 tgccgatacc atttggacca acgatagcga cagcattcat cttacgaaga tctacgttaa
     9481 tcggttgtga caggacttcc ccgtcataac caatagcagt attttcaaca gtcaaaacaa
     9541 cattgcccga cgttttttta gactggaagg tcatgttggc tgctttcttg ccagcttcag
     9601 gcttgtccaa acgctccatt ttttctagtt gtttacggcg agattgagca cgtttagtcg
     9661 ttgaagcacg aactagattg cgattgacaa agtcttccag agcagcgatt tccttctgtt
     9721 gcttttcata gttttttgcc tcagtagcta gcttttgctc cttcaattcg acaaaacgag
     9781 agtaattccc cacatagcga tccaaggaat gcttggtcaa atctagcgta attgtcgcaa
     9841 ccttgtccaa gaaataacgg tcgtggctga cgataatgag ggcaccgcta tagtttacca
     9901 agtaattctc tagccaggcg atggtttcaa tatccaagtg gttagttggc tcgtccaaga
     9961 ccaagagatt gggcttttca aggagcattt tagctagagc caaacgagta ttttgaccac
    10021 ctgaaagttc agctattttc atctgccaca tagactcgtc aaacttgaat ccattcaaaa
    10081 tcgctcgaat atcagcttca taggtaaagc cgcctgcttg gcgaaaattc tcagataagt
    10141 ggtcgtaatc tgacatcagt ttatccaatt catcgccaga cttttcaccc atctccaact
    10201 ccatctgacg aagttgttta tctgtccgac gtaagtcatc aaagacatga agcatctcat
    10261 catagatggt attttcagac tcaaaacggc tatcttgagc taggtaagac agagaaatat
    10321 cttttttctt attgatttct ccactagttg gctcctcttc tccaactaaa atcttcaaaa
    10381 gagtagactt acctgcacca tttttcccaa caagggcaat ccgatctcgt tcatcaacct
    10441 gcaggttgat attatcgaaa agaacctctc ctgcaaaaga acgttcaatt ttattagctt
    10501 gtaaaataat catacaagta gtatagcatg tttccctaag tcattcaaga taatcgtaa
//
LOCUS       DAVLBN010000065        10423 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLBN010000065 DAVLBN010000000
VERSION     DAVLBN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.065"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            180..2108
                     /gene="glgB"
                     /locus_tag="VXC24_001788"
     CDS             180..2108
                     /gene="glgB"
                     /locus_tag="VXC24_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0493866.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2098..3240
                     /locus_tag="VXC24_001789"
     CDS             2098..3240
                     /locus_tag="VXC24_001789"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0493867.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3230..4369
                     /gene="glgD"
                     /locus_tag="VXC24_001790"
     CDS             3230..4369
                     /gene="glgD"
                     /locus_tag="VXC24_001790"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0493868.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4366..5799
                     /gene="glgA"
                     /locus_tag="VXC24_001791"
     CDS             4366..5799
                     /gene="glgA"
                     /locus_tag="VXC24_001791"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0493869.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5858..6229
                     /locus_tag="VXC24_001792"
     CDS             5858..6229
                     /locus_tag="VXC24_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0493870.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVPGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6269..6502
                     /locus_tag="VXC24_001793"
     CDS             6269..6502
                     /locus_tag="VXC24_001793"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0493871.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            6511..7627
                     /locus_tag="VXC24_001794"
                     /pseudo
     CDS             6511..7627
                     /locus_tag="VXC24_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(7624..8070)
                     /locus_tag="VXC24_001795"
     CDS             complement(7624..8070)
                     /locus_tag="VXC24_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0493872.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8234..9538
                     /gene="eno"
                     /locus_tag="VXC24_001796"
     CDS             8234..9538
                     /gene="eno"
                     /locus_tag="VXC24_001796"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0493873.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9711..10423)
                     /locus_tag="VXC24_001797"
                     /pseudo
     CDS             complement(9711..10423)
                     /locus_tag="VXC24_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3127 a         1850 c         2309 g         3137 t
ORIGIN      
        1 tagaaaaaga aaggtgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag
       61 taagtgaact tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc
      121 ttctctaaaa aggtagtata ataaaaacat agaaaacgct tacaggagaa agggagtata
      181 tggataatag agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt
      241 atctaggagc acatagggaa gaactaaatg gagagtatgg ctataccttc cgtgtttggg
      301 cacctaatgc tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga
      361 ttccaatggt aagaaaggac tttggggtct gggaagtctt taccaatatg gctcaagaag
      421 ggcatattta caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc
      481 cttttgctgt caggtatgag gctcgtccag gaacaggggc aatcgtaaca gagcttcctg
      541 ataagaaatg gagggatgga ctttggctgg cacgaagaaa acgttggggc tttgctgaac
      601 gtcctgtcaa tatttacgag gttcatgctg gctcttggaa gagaaatcct gatggcagtc
      661 cttatagttt tgcccaattg aaagatgaac tcattcctta cctagttgag atgaactata
      721 ctcatattga gtttatgccc ttgatgtccc acccactagg tttgagttgg gggtaccagc
      781 ttatgggtta cttcgcttta gagcatgcct atggtagacc agaggagttt caagattttg
      841 tcgaggagtg tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta
      901 ccatcaatga tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc
      961 ataataaggc tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag
     1021 tccagtcctt cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta
     1081 ttcgtgtgga tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac
     1141 ctaataaaga tggcggaaat ctcaactatg aaggttatta tttccttcag cgcttgaatg
     1201 aggttattaa gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcga
     1261 ccaatattac gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg
     1321 gctggatgaa tgatatcctc cgtttctacg aagaagatcc gatctatcgt aagtatgact
     1381 ttaacctggt gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct
     1441 cgcacgatga agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt
     1501 acaatcaatt cgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga
     1561 aattgctctt catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt
     1621 tggaatggtc taacctagaa gacccaatga atgctaagat gaagtatttc acttctcagc
     1681 taaaccagtt ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta
     1741 ttgaaatcat tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta
     1801 aaaagggaga aatgttagtc tgtatcttta atatggtacc tgttgagcgg aaagatttta
     1861 caatcggact acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt
     1921 ggggaggcgt ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag
     1981 attatgagca gaccttaacc tttaccctac cggctatggg agcaagtgta tggaaaatca
     2041 aacgtcgctt gaaatctact aaaaccgtca caaataaaaa ccaaaaagga gtagaaaatg
     2101 aaaaatgaaa tgttagcttt gattcttgct ggtgggcaag gaactcgtct cgctaaactc
     2161 actcaaagca tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt
     2221 gccctatcaa actgtgccaa ctcagggatt cacaatgttg gggtcgttac acagtatcaa
     2281 ccacttgctc tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattgat
     2341 tcaggtgtct ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgagggg
     2401 actagtcacg ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc
     2461 ttgattttgt ctggggatca catctacaaa atggactatg atgatatgct ccagtctcat
     2521 aaggataata atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc
     2581 cgttttggta tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca
     2641 gctcaaccta aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt
     2701 cgtaatatgt tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat
     2761 gtcattccaa attaccttga gttaggtgaa agtgtttatg cttacgaatt tagtggttat
     2821 tggaaagatg ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca
     2881 gaaaatgcct tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca
     2941 ccaccaaact tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt
     3001 ttcgttgatg gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga
     3061 gcggaagtcc ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt
     3121 aaacgtgcca ttattggtga aggtgcgatt atttctgacg gtgtcgaaat tgatggaaca
     3181 gatgaagtac aagttgtagg atataatgaa gtagtggggg tagcaacaga tgaagattga
     3241 taaatattct gccattttag gaaatacagt tggttttcac aatatgtcga cattgacgga
     3301 ccaccgtcca gtagcaagtt tgccatttgg tgggaaatat cgtttgattg acttcccact
     3361 ttcaagcctt gctaatgcag gtgttcgtag tgtctttggt attttccagc aggataatat
     3421 cagctcagta tttgaccata ttcgttcagg acgcgagtgg ggcttatcaa cccttcttag
     3481 ccattactat ctaggaattt acaatacccg tgtagaaagt agtacagttg gaaaagaata
     3541 ctaccaacag cttcttactt atttgaaacg ttctggctca aaccaaacgg ttgccctcaa
     3601 ctgcgatgtt cttattaaca ttgatttgaa ccaagttttc cacctacata gtacaacaaa
     3661 agagcctatc actgtagttt ataaaaaact agctaagaaa gatatttcag aagtaaatgc
     3721 aatcttggat gtagatgaaa cagaccatgt tctttctcat aaactctttg atagcaagtc
     3781 aacagctgaa acgttcaata tgtctacaga tatctttgtc gttgatacac cttggttgat
     3841 tgaacacttg gaagaagaag ctaaaaaaga acatccagag aaattgcgct atgttttacg
     3901 ggatttggct gtaaaagagg gagctttcgc ctacgagtac acgggctatc tagccaatat
     3961 tcactctgtt aaatcttatt atcaagcgaa tatcgatatg cttgaatcac aaaaattcta
     4021 ttctcttttc tcaccaaacc aaaagattta tacaaaggtc aaaaacgaag agccaactta
     4081 ctatgctaat acatctaagg taagcacttc tcagtttgcc tctggtagta ttattgaagg
     4141 tcaagtagct aattctgttc tatcacgtaa tattcatgtc cataaggata gcttggttaa
     4201 agatagcctg ctcttccctc gtgttgttat tggagaaggg gctcaggtcg aatatgctat
     4261 cttggacaaa ggggttgaag ttgagcctgg tgttgtgatt cgaggaactg cagaacatcc
     4321 agttgtggtt aagaaaggtg ctaaagtaac agaggatatt cattcatgaa aattttattt
     4381 gtagcagcag agggtgcacc cttttcaaaa acaggtggtt tgggagacgt cattggcgct
     4441 cttccaaaat cactggtaaa agctgggcac gaagttgcag tgattttacc ctactatgat
     4501 atggtagagg ctaaatttgg aaatcagatt gaagatgtgc ttcattttga ggtgagcgtt
     4561 ggttggcgca gacagtattg tggaattaag aaaacagtat taaatggtgt aaccttctac
     4621 tttattgaca atcaatatta tttcttccgt ggtcatgttt acggtgattt tgatgacgga
     4681 gaacgctttg cctttttcca actggctgcc attgaggcta tggaaaggat tgactttatt
     4741 cctgatcttc tccatgttca tgactaccat acagctatga ttcctttctt gttgaaggaa
     4801 aaataccgtt ggattcaagc ctatgaggac attgaaacag ttttaaccat tcataattta
     4861 gaattccaag gacaattttc agaaggaatg ttgggtgatt tgtttggagt tggctttgaa
     4921 cgttacgctg atggcaccct tcgatggaac aactgtctga actggatgaa ggcaggtatt
     4981 ctctatgcga accgtgtttc aaccgtttca cctagctatg ctcatgaaat tatgactagt
     5041 cagtttggat gtaatttgga tcagattctt aaaatggagt ctggtaaagt atctggtatc
     5101 gtgaatggga ttgatgctga tctttataat cctcagacgg atgctctttt agactatcat
     5161 ttcaatcagg aagatttgtc tgggaaagcc aaaaataagg caaaattgca agaaagagtt
     5221 ggcttgcctg ttagagcaga cgttccactg gtgggaattg tttctcgttt gacacgtcaa
     5281 aaaggttttg atgtggtggt cgaaagtctt caccatatct tgcaagaaga tgttcagatt
     5341 gttcttttgg gaactggcga tccagccttt gaaggagctt tctcatggtt tgctcagatt
     5401 tacccagaca agctatcaac aaatatcact tttgatgtca aacttgctca ggaaatctac
     5461 gctgcttgtg acctcttcct catgccaagt cgttttgaac cgtgtggctt gtctcaaatg
     5521 atggctatgc gttatggaac cttgccattg gtccatgaag ttggaggctt gcgagataca
     5581 gttcgcgctt tcaatccaat cgaaggaagc ggtactggct ttagctttga caatctatct
     5641 ccttattggt taaattggac tttccaaaca gcattggact tgtatagaaa ccatccagac
     5701 atttggagaa acctacaaaa acaagctatg gagagtgact tctcatggga tacagcctgc
     5761 aagtcatacc ttgacttgta ccatagttta gttaattaat agataaaatc gtatgatgac
     5821 ttcatacgat ttttaggctg tttagagagg agaactgatg tctcaagtaa aaggcttgtg
     5881 tgttttggat gtagatggaa ccttaatcct agaagaagtg attgatcttt tagggagaga
     5941 ggcaggtcat gaggcggaaa tttcgcagat tacaagtcga gcaatgcgag gagagttggt
     6001 ctttgaaagc agtttaagaa aaagagtgtc cttgttggaa ggtcttccta ttttggtctt
     6061 tgataacgtc ttcaactcaa ttcatctatc gctaaatgtc ccagagttca tctctattct
     6121 ccaaaagaat ggcatcctag ttggtctggt gcctggtgga tttacaccaa tagttggaga
     6181 gattagcaaa atcccttggt attgcctatt tcactgccaa ccagcttgaa gtcaaagaag
     6241 gtttttaaca ggaaaattag ttggacaaat tataagtccc caggtcaaaa aagaaactct
     6301 ggaaaaatgg agaaagaaac taaaactttc taaagaaaga acggtggcaa tcggtgatgg
     6361 ggtcaataat ctattaatgt tgaagtcggc ggagttagga atcgcctttt gttccaaaga
     6421 aatgctcaaa aaagaaatac cacatcatgt tgacaagagg gattttttag aagttcttcc
     6481 tttgattgac tgtttagaat gagggaaaat atgaagattg taattgcacc ggattcgttt
     6541 aaggaaagct tgacagctca acaggtagct gaagcaataa aaagaggctt ccaacaatcg
     6601 atagcagatg tagaatatct cctctgccct gttggtgatg ggggagaagg tactgtagat
     6661 gctatccgac attctcttga cctaaaagaa aaatggatcc aagtgacaga cccttttgga
     6721 caaaaagaag ccatgcgcta ttttcaaaaa ggggaactgg cactatttga agtagctgac
     6781 ttggttggtc ttggaaaaat tccgctagag aaacgaaatc cacttcaaat ccaaacttgt
     6841 ggtattggag agttgattct ccatctcatt tctaaaggga ttaaagatat ttatatcggt
     6901 gttggtagca cggccagtaa tgatggagga ctggggattg ctgctggttt aggttatcaa
     6961 ttttatgata gggatggaaa tgtcttgcct gcttccagtc aatccttatt aaacttagct
     7021 tctgtttcaa cagaaaattg ctataaaatt cctgaaggtg ttcaaattca tattctagca
     7081 gatgtcgtga gtcccttatg tggtcatcaa ggtgcgactt acacttttgg caatcaaaaa
     7141 ggtctacatc cgactatgtt tgcagtcgta gatcaggcga tccaagattt ttatgaaaaa
     7201 ttctcacctg caacattaga aattaaagga gcaggagcag gtggaggcct tgctggtggt
     7261 ttgtgtgcct ttgctcaggc aagtatcgtg tctggaattg ataccttgct tggacttaat
     7321 caactttgat aagaaagttt cagatgctga cttgcttgtt gttggagaag gaagacttga
     7381 cagtcaaagc tttgctggga aagcgcctat aggtgttgca aaaagaaccc ctgttggagt
     7441 tcctgttatt gctatttgcg gtagtcttgc tgaagattta cctcccctac catttgaaaa
     7501 tatccaagct gtcttttcta ttttggagaa aagtgaacct ttagaagata gtttgaaaaa
     7561 tgccagtctc tatctggagc gcacggctgc caatattggg cacttattaa atatgtgcaa
     7621 gatttagcta aaccatttct tccataagga tgttttggct ggttcttcct ttttaacttc
     7681 ccaaagtttt ggaaaagcaa gtcgaaggtc tttttcttct acttgaactg gtgcattgct
     7741 atgaataacc aggccaaaag gagaagtaat atgctcttca gatactatgg tggcttgact
     7801 atcagtttct tttgcttctt ttaagtagaa aacttgctta tcaaattcga tagttggtga
     7861 aatcttcaca aatagtggct ctgctttttc ctgaaggttt tctaaaataa ataaaaagcc
     7921 tttttctaac tgagggctat ttgctgtgtc aatatctaca tatccaagaa ctctttcctc
     7981 aaaagtacca agatagcgtc tttgctcatc cggatttatt tttaacccac catgagcttt
     8041 ttcaagtaat tgttttgata aatctgtcat gaaaacagta tatcataaaa gttagaataa
     8101 aacagacaaa agaaagcgat tactttataa agttaaggaa aagttgcaca aagataacgt
     8161 tttttcttga aaaaggaggg gttttaaggt attatagagg tgtaaaaaat ttaactcata
     8221 aggagagtaa aaaatgtcaa ttattactga tgtttacgct cgcgaagtcc tagactcacg
     8281 cggtaaccca acacttgaag tagaagttta cactgaatca ggtgctttcg gacgtggtat
     8341 ggttccatca ggagcttcta ctggtgaaca cgaagcagtt gaacttcgcg acggtgacaa
     8401 atctcgttac ggtggtcttg gtacacaaaa agctgttgac aacgtaaaca acatcattgc
     8461 tgaagctatc attggctacg atgtacgtga tcaacaagct attgaccgtg ctatgatcgc
     8521 acttgacggt actcctaaca aaggtaaatt gggtgcgaat gcaatcctcg gtgtgtctat
     8581 cgctgtagct cgtgctgctg ctgactacct tgaaatccca ctttacagct accttggtgg
     8641 attcaacact aaagttcttc caactccaat gatgaacatc atcaacggtg gttctcactc
     8701 tgacgctcca atcgctttcc aagagttcat gatcttgcca gttggtgcgc caacatttaa
     8761 agaagccctt cgttacggtg ctgaaatctt ccacgctctt aagaaaatcc ttaaatcacg
     8821 tggtttggaa actgccgtag gtgacgaagg tggattcgct cctcgtttcg aaggaactga
     8881 agatggtgtt gaaactatcc ttgctgcgat tgaagctgct ggatatgtac caggtaaaga
     8941 cgtatttctc ggatttgact gtgcttcatc agaattctac gataaagaac gtaaagttta
     9001 cgactacact aaatttgaag gcgaaggtgc tgctgttcgt acatctgcag aacaaatcga
     9061 ctaccttgaa gaattggtta acaaataccc aatcatcact attgaagatg gtatggatga
     9121 aaacgactgg gatggttgga aagctcttac tgaacgtctt ggtaagaaag tacaacttgt
     9181 tggtgacgac ttcttcgtaa caaacactga ctaccttgca cgtggtatcc aagaaggtgc
     9241 tgctaactca atccttatca aagttaacca aatcggtact cttactgaaa cttttgaagc
     9301 tatcgaaatg gctaaagaag ctggttacac tgctgttgta tcacaccgtt caggtgaaac
     9361 tgaagattca acaatcgctg atatcgcagt tgcaactaac gcaggacaaa tcaagactgg
     9421 ttcactttca cgtacagacc gtatcgctaa atacaaccaa ttgcttcgta tcgaagacca
     9481 acttggtgaa gtagctgaat atcgtggatt gaaatcattc tacaacctta aaaaataaaa
     9541 tagttcagtg aactatttta tcccgaacca tgaaattcaa aagttcggcc gttgatttaa
     9601 caacgtttct agcccctcgg attttatccg aagggctatt tttgtattta gagggcaaaa
     9661 aagggacaaa actttttggc tctttgtcaa ctgtagtggg ttgaagtcag ctaagctcga
     9721 gaaaggacaa attttgtcct ttcttttttg atattcagag cgataaaaat ccgttttttg
     9781 aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat gagattattg
     9841 gtcgcttcca atttggcgtt tgaatagggt agttgaaggg cgttgacgat tttctctttg
     9901 tcctttagaa aggttttaaa gacagtctga aaaagaggat gaacctgctt tagattgtcc
     9961 tcaatgagtc cgaaaaattt ctccggtttc ttattctgaa agtgaaacag caagagttga
    10021 tagagctgat agtggtgttt caagtcttgt gaatagctca aaagcttgtc taaaatctct
    10081 ttattggtta agtgcatacg aaaagtagga cgataaaatc gcttatcact cagtttacgg
    10141 ctatcctgtt gaatgagttt ccagtagcgc ttgatagcct tgtattcatg ggattttcga
    10201 tgaaactgat tcatgatttg aacacgcaca cgactcatag cacggctaag atgttgtaca
    10261 atgtgaaagc gatcaagaac gatttcagca ttcgggagtg aaacagtctg ggagactgtt
    10321 tcagcctgag cctagaaatt tgaaagcgaa gctgtttagc caagtcatag taagggctaa
    10381 acatatccat agtaataatt ttgacgcgac atcggacaac tct
//
LOCUS       DAVLBN010000066         9961 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLBN010000066 DAVLBN010000000
VERSION     DAVLBN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.066"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(71..307)
                     /locus_tag="VXC24_001798"
     CDS             complement(71..307)
                     /locus_tag="VXC24_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0493874.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /locus_tag="VXC24_001799"
     CDS             complement(375..1295)
                     /locus_tag="VXC24_001799"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0493875.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="VXC24_001800"
     CDS             1493..1897
                     /locus_tag="VXC24_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493876.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2113..2694
                     /locus_tag="VXC24_001801"
     CDS             2113..2694
                     /locus_tag="VXC24_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0493877.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3967
                     /locus_tag="VXC24_001802"
                     /pseudo
     CDS             2691..3967
                     /locus_tag="VXC24_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
     gene            3985..4647
                     /gene="deoC"
                     /locus_tag="VXC24_001803"
     CDS             3985..4647
                     /gene="deoC"
                     /locus_tag="VXC24_001803"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0493878.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4634..5023
                     /locus_tag="VXC24_001804"
     CDS             4634..5023
                     /locus_tag="VXC24_001804"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0493879.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5113..6165
                     /locus_tag="VXC24_001805"
     CDS             5113..6165
                     /locus_tag="VXC24_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0493880.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6309..7844
                     /locus_tag="VXC24_001806"
     CDS             6309..7844
                     /locus_tag="VXC24_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493881.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7837..8895
                     /locus_tag="VXC24_001807"
     CDS             7837..8895
                     /locus_tag="VXC24_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493882.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8898..9854
                     /locus_tag="VXC24_001808"
     CDS             8898..9854
                     /locus_tag="VXC24_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0493883.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         2832 a         1759 c         2297 g         3073 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaac gagacggtca agaactgact tcaagtgaaa ttgaatggct
     2761 ggtagaaggc tatgtgtcag gaactgttcc tgattatcag atgtctgcct ttgctatggc
     2821 tgtttatttt aaaggaatga cgactcgaga aatctctgat ttaacgatga atatggttaa
     2881 gactgggcaa gagtttgacc tgtcagccat tgatggtgtg aaagttgaca agcattctac
     2941 tggtggtgtc ggcgataagg taaccttgat tttagttcct cttgttgcta gcttcggtgt
     3001 gcctgtagca aaaatgagtg gtcgtggtct tggccataca ggcggaacaa ttgataaatt
     3061 ggagtccatt aagggctatc aagtagaacg tagtcaagag gattttattc gtcaggttca
     3121 ggatattgga gtatctgtca ttgggcaatc agaccagctg gtcaaagcag ataagcttct
     3181 ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt cctttgattg cgagttcggt
     3241 gatgagcaag aaaattgcgg caggggcgga tgctattttg ctagacgtga ctgtcggtga
     3301 gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg gctcaaacta tggtagatct
     3361 tggtaaggtt gttggacgga agacagtagc agtgattacg gatatgagcc agcctttggg
     3421 acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg gagattttgc aaggtcaagg
     3481 acgtcaggat attacccact ttatttgtga attggctcaa attatgcttg gtttggcaaa
     3541 tgttaacaaa actgttgaag aagttcgcca acatcttgag aatggtcaag cactggctaa
     3601 gtttgaggaa atggtgcaag cccaaggtgg agacttggaa gacctctatc gtcctgtaaa
     3661 tgtagctcat gtggtggaaa tccctgctca ggaaacgggt gtcatttcag ctcttccagc
     3721 tatggacttt ggtctttatg ccatgaggct gggtgctggt cgtgcagtta agtctgatgc
     3781 cttggactat gaaacaggaa ttgtttttga aaagaagatt ggagactccg ttcaaaaggg
     3841 tgaaattgtt gcaaaagtat acacaaatga aaaaattcca cctcaactag ttacagattt
     3901 ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc cgtgaaattg tagaaatcat
     3961 ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat atatagatca tacgctttta
     4021 aaacaagatg caaagaaaaa acaaattgat agtttgttgt ctgaggctag agagtatgac
     4081 tttgccagtg tttgcgttaa tccgacctgg gttgaacatg ctaaaaaagg acttgaaggc
     4141 acagatgtta aggtttgcac agtagtaggt ttccctttgg gagcaacaac ttcagccgtg
     4201 aaagcatttg agacaaaaga agctatccaa aatggtgcag atgagattga tatggtgatc
     4261 aatgttggag ctctcaaatc aggtaattta gccttggttg agtcagatat tcgcgcagta
     4321 gtggaagcaa gtggtgataa gttagtgaaa gtcattattg aagcttgcct tctgacagac
     4381 caagaaaaaa ttgttgtttg ccaattggcc caaaaagctg gggctgactt tgttaaaaca
     4441 tctactggtt tttcaactgg tggtgctacg atagcagatg ttacattaat gcgtgaaaca
     4501 gttggatctg atatgggagt caaggctgct ggtggagctc gttcttatgc agatgctctt
     4561 gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag ctggggtagc tattttaaaa
     4621 ggagaattgg cagatggcga ctactgagtt gattgaactg gcaattgaaa ccagcaaaca
     4681 tgcatatgtc ccctattctc actttcctat cggagcagtt ttagtagcca aagacggaag
     4741 tgtttacacg ggagtgaata tcgaaaatgc tagctatcct ttgaccaatt gcggtgagag
     4801 aacagctatt tttaaggcta tatctgaagg ccaaagagaa ttttcagaat tgattgtcta
     4861 tggtcaaact gaaaaaccga tctcgccatg tggtgcttgt cgccaagtga tggctgaatt
     4921 ttttgaacaa gatctaaaag tgaccttagt cgcaaaagat aaatcgacgg tcgagatgac
     4981 ggtcggggaa ttacttccat actcttttac agacttaaac tagtctgagt cgctctctga
     5041 gtggcacggt ccttgtggcc aaccaatcca tacttgcaac atcgttgcac atcttattta
     5101 ggaggttcag taatgaacaa gaaacaatgg ctaggtcttg gcctagttgc agtggcagca
     5161 gttggacttg ctgcatgtgg taaccgctct tctcgtaacg cagcttcatc ttctgatgtg
     5221 aagacaaaag cagcaatcgt cactgatact ggtggtgttg atgacaaatc attcaaccaa
     5281 tcagcttggg aaggtttgca ggcttggggt aaagaacaca atctttcaaa agataacggt
     5341 ttcacttact tccaatcaac aagtgaagct gactacgcta acaacttgca acaagcggct
     5401 ggaagttaca acctaatctt cggtgttggt tttgcccttc ataatgcagt taaagatgca
     5461 gcaaaagaac acactgactt gaactatgtc ttgattgatg atgtgattaa agaccaaaag
     5521 aatgttgcga gcgtaacttt cgctgataat gagtcaggtt accttgcagg tgtggctgca
     5581 gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg gtatcgaatc tgaagttatc
     5641 tctcgttttg aagcaggatt caaggctggt gttgcgtcag tagacccatc tatcaaagtc
     5701 caagttgact acgctggttc atttggtgat gcggctaaag gtaaaacaat tgcagccgca
     5761 caatacgcag ccggtgcaga tattgtttac caagtagctg gtggtacagg tgcaggtgtc
     5821 tttgcagagg caaaatctct caacgaaagc cgtcctgaaa atgaaaaagt ttgggttatc
     5881 ggtgttgatc gtgaccaaga agcagaaggt aaatacactt ctaaagatgg caaagaatca
     5941 aactttgttc ttgtatctac tttgaaacaa gttggtacaa ctgtaaaaga tatttctaac
     6001 aaggcagaaa aaggagaatt ccctggcggt caagtgatcg tttactcatt gaaggataaa
     6061 ggggttgact tggcagtaac aaacctttca gaagaaggta aaaaagctgt cgaagatgca
     6121 aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa aataatggat ggaagtcatt
     6181 tcttaggaag cggccaaggg ccgctttttt aagagttgag acaaagtcat tttgtctcag
     6241 taaagcttgc tactagacaa actagcaagt tttattgaaa taaaataaga ctctgaaagg
     6301 aagagcacat ggcacacgaa aatgtcattg agatgcgtga tattaccaag gtgtttggtg
     6361 gatttgttgc caacgacaaa atcaacttgc acctacgaaa aggtgaaatt catgcacttt
     6421 taggagaaaa tggggctggt aagtccacgc taatgaacat gttagcaggc cttcttgaac
     6481 caactagtgg tgaaatcgcg gtcaacggtc aagttgtcaa tctcgactcc ccatctaaag
     6541 cagctagctt gggaatcggg atggttcacc agcactttat gttggttgaa gccttcacag
     6601 tggctgaaaa catcatttta ggtagtgaat tgactaaaaa tggtgtgcta gatatcgctg
     6661 gagctagcaa agaaatcaag gctctttctg aacgttatgg cttagctgtt gacccttctg
     6721 ccaaggtagc agatatctca gttggagccc aacaacgtgt agaaatttta aaaacacttt
     6781 atcggggggc tgatatcctt atctttgacg aaccaacggc tgttttgact ccatcagaaa
     6841 ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga aggaaaatca attatcttga
     6901 ttacccacaa attggatgaa attcgcgcag tttctgaccg tgttacagtt atccgtcgtg
     6961 ggaaatcaat tgaaaccgtt gaaattgcag gggctaccaa tgctgatttg gcggaaatga
     7021 tggtaggacg ttctgtttcc tttaaaacag agaagcaagc ctctaaacca aaagaagtgg
     7081 ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg tgttccagct gttaaaaatc
     7141 tgtccttgga tgttcgtgct ggagagattg ttggtattgc ggggattgat ggaaatggtc
     7201 agtctgaact gattcaagcc attacaggtc ttcgtaaggt tgaatctggt agcattgagc
     7261 taaaagggga ttcaattgta ggcttgcacc cacgtcagat tacagaacta agtgttgggc
     7321 acgttccaga agaccgtcac cgtgatggct tgattttgga aatgatgata tctgaaaata
     7381 ttgcccttca aacctactat aaagaaccac atagtaaaaa tggaattttg aattattcaa
     7441 atattacttc ttatgctaaa aagctgatgg aagagtttga tgttcgcgct gccagtgaat
     7501 tagttcctgc agctgcactc tcaggaggaa atcaacaaaa agcaattatt gctcgtgaaa
     7561 ttgatcgaga tcctgatctc cttatcgtta gccagccaac tcgtgggttg gatgtcggtg
     7621 ccattgagta tatccacaaa cgcttgattg aagagcgtga taatggcaag gctgtccttg
     7681 ttgtcagctt tgaattggat gagattttaa acgtctcaga ccgtattgcc gttatccacg
     7741 atggtaagat tcaaggtatt gtatcaccag aaacaaccaa taaacaagaa cttggtgtct
     7801 tgatggctgg tggaaacttg ggaaaggaga agagtgatgt ttaaaaaatt acaacaaatt
     7861 tcggttccct tgatttctgt atttctagga attttactcg gagccattgt catgtggatc
     7921 ttcggttatg atgctatttg gggctacgaa gaattgttct atacagcctt tggcagtctg
     7981 cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg tcttgattgg tcttggtttt
     8041 gcggttgcca gtcgagctgg tttctttaac gtcggacttc ctggtcaggc tttggcaggt
     8101 tggattctca gtggttggtt tgccctgtcg catccagata tgccccgtcc cttgatgatt
     8161 ctagcaacca tcgtgattgc cttgattgct ggtgggattg tcggagcgat tccaggtatt
     8221 cttagggcct atctagggac gtcagaggtt attgtaacca tcatgatgaa ctacattgtc
     8281 ttgtatgtag ggaatgcctt tatccatgct ttccctaaag acttcatgca aagtacagat
     8341 tcgaccattc gtgttggggc taatgcaacc tatcagacac cttggttggc tgagttgact
     8401 ggtaactcac ggatgaatat tggtattttc tttgccatca ttgccgttgc agttatttgg
     8461 ttcatgctca agaaaacaac tcttggtttt gaaatccgtg cagttggtct taatccacat
     8521 gcttcagaat atgctggtat ttctgccaag cggactatta tcctatctat gattatttca
     8581 ggtgccttgg caggtcttgg tggagctgtt gaaggtttgg gaaccttcca gaacgtctat
     8641 gttcaaggtt cgtcattagc tatcggattt aacggaatgg cggttagttt gcttgcggcc
     8701 aactcaccaa ttggtatact ctttgcagcc ttcctatttg gcgttctcca agttggggct
     8761 cctggtatga atgctgcgca ggtaccatct gagcttgtca gcattgtaac agcgtctatt
     8821 atcttctttg tcagtgttca ttaccttatc gaacgctttg ttaaaccgaa aaaacaagtt
     8881 aaaggaggta agtaaagatg tctattataa ccttgctccc cctcttggtg tcttctatgc
     8941 tgatttactc agcacctctc atctttacaa gtatcggtgg tgttttctct gaacgtggtg
     9001 gtgtggtaaa cgttggcctt gaaggaatta tggttatggg tgccttttct ggagttgtct
     9061 ttaaccttga atttgcagaa caatttggag cagcaactcc atggctatcc ttgcttgtag
     9121 caggattggt tggtagtgtt ttctctatca tccacgcagc agcgacggtt catttccgtg
     9181 cagaccatgt tgtcagcggt acggtattga acttgatggc gcctgccttg gctgttttct
     9241 tagttaaagt tctttataac aaaggacaaa ccgacaacct aagtcaaact tttggacgct
     9301 ttgatttccc agtcttggca aatatcccag tgattggtga tatcttcttc aagtcaacta
     9361 gtctacttgg ttatctggcg attgccttct cattccttgc ttggtttatt ctctttaaga
     9421 ctcaatttgg tcttcgtctc cgctctgtcg gtgaacatcc tcaagcagcg gataccttgg
     9481 gaatcaacgt ctacaagatg agatatttag ggattattat ttcaggtttt ctaggtggaa
     9541 ttggcggagc gatttatgcg caatcaatct cagttaactt ctcagtgaca actattgttg
     9601 gacctggatt tatcgccctt gctgcgatga tctttgggaa atggaatcca atcggtgcta
     9661 tgctttctag tctcttcttt ggactttcac aaagtttggc tgttatcggt tctcaattgc
     9721 cgttcctaca aggagtgcca gcggtttatc ttcaaattgc accttatgtt ttgacaattc
     9781 ttgtcttagc agccttcttt ggaaaagcag tcgcaccaaa agcagatggt atcaactaca
     9841 tcaaatcaaa ataagcatac aaaaaaacgt cagttcaatg actgaactgc cccccaaaag
     9901 ttagacagaa aaaatctaac ttttggggtg tttttattat gaaactaact tatgatgata
     9961 a
//
LOCUS       DAVLBN010000067         9847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLBN010000067 DAVLBN010000000
VERSION     DAVLBN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.067"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            312..407
                     /locus_tag="VXC24_001809"
                     /pseudo
     CDS             312..407
                     /locus_tag="VXC24_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(660..1280)
                     /locus_tag="VXC24_001810"
     CDS             complement(660..1280)
                     /locus_tag="VXC24_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0493884.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1280..1762)
                     /locus_tag="VXC24_001811"
     CDS             complement(1280..1762)
                     /locus_tag="VXC24_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0493885.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1762..2604)
                     /locus_tag="VXC24_001812"
     CDS             complement(1762..2604)
                     /locus_tag="VXC24_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0493886.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2699..3499)
                     /locus_tag="VXC24_001813"
     CDS             complement(2699..3499)
                     /locus_tag="VXC24_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0493887.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3643..5022
                     /gene="glmU"
                     /locus_tag="VXC24_001814"
     CDS             3643..5022
                     /gene="glmU"
                     /locus_tag="VXC24_001814"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0493888.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            5032..5577
                     /locus_tag="VXC24_001815"
     CDS             5032..5577
                     /locus_tag="VXC24_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0493889.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5589..5903
                     /locus_tag="VXC24_001816"
     CDS             5589..5903
                     /locus_tag="VXC24_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0493890.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            5920..6612
                     /locus_tag="VXC24_001817"
     CDS             5920..6612
                     /locus_tag="VXC24_001817"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0493891.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6689..7180
                     /gene="rocS"
                     /locus_tag="VXC24_001818"
     CDS             6689..7180
                     /gene="rocS"
                     /locus_tag="VXC24_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0493892.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7278..7868
                     /locus_tag="VXC24_001819"
     CDS             7278..7868
                     /locus_tag="VXC24_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0493893.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7877..9640
                     /locus_tag="VXC24_001820"
     CDS             7877..9640
                     /locus_tag="VXC24_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0493894.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3048 a         1709 c         2092 g         2998 t
ORIGIN      
        1 gatctgaact ttatcatcat aagttaattt cataataaaa acaccccaaa agttagattt
       61 tttctgtcta acttttgggg tgtagttcat gtacacctga tatgatgcgt tttataattt
      121 taaagacttt ttgaccagcc tcattttttt aacttgatac tcagtgaaaa gcaaagatta
      181 aactaggaag ctagctgtag gctgctcaaa gaacagcttt gaggttgcag ataaaacttg
      241 tgaggtcacc aacatatata atgtgaagct gacgtggctt gaatagattt tagaagggta
      301 tgagtctgga agttttaatg gataatgcaa gattccatag aatgggtaag ctagagttct
      361 tatgtgaaga gtttgggcat aaacttttac cttttcctcc ctactcatct tagtatagaa
      421 aagtgaatct aaaatagtac ataactgctt ctaaaacatt cttataaatt gatttaaatt
      481 ctcaaatcat attattcagt tcttatttca ttttgctcta caatcctgtt gagaagacac
      541 gtgttcatat caaaaaggta ttggcaagtt gcaatacctt tttacaaggt tcttttgtct
      601 tatttttgtt tcaactgact atatctccta tggttctagt tcagaaggct aggctataat
      661 tatgattgat aagaagtatc attccaagta ttgagagtga atgtttcaaa atcatgggtt
      721 tctataatgg tcaggctggc atttgctaga ccgccatctt tacgaagaag tggttcttta
      781 tagcctagga gagtacgaag actggcagta agattggcgc cgtgtccgac aattagaata
      841 cgctcagctg gactatcttt taatgatttg ataaattgga tggtccgttg agttgtacta
      901 tagagggatt cggctccgaa cattcgagtg tcaaattgag caagatttga acgaaaagcc
      961 tggatttgtt gcgggtaaat agcttccaag gttgcaattt tcaaaccttc taacttccca
     1021 agttgccatt cacggagatt aggaacgatt tctaaagaac agggggtata gagttgactt
     1081 tggataatct cagcagattt gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa
     1141 ggaatttcct tgagatactg gccaagtcgt tttagggttt caatggattc aggaagaaga
     1201 ggagaatcac cgctagcacc ttgaaaacga ccttcttggt tccagagggt acgaccgtgg
     1261 cggacaaagt agagtttcat tacttgatgt cctccaaaat atctacaaag tctgccttta
     1321 caaagctagc caagtcttgt ggcgcgacga taatgctgtg tccgacttcg cctgcagaga
     1381 caatcattcg atccaaatct agagcaattt tatcgataaa aatgggataa ttgtgtttct
     1441 gacgaattcc gacaggatta ttggctccat gaatgtaacc agttgttttt tctaagtcct
     1501 tttgtggaat catgctcact tttttattgc cagaaatttt agctagtttc ttttcagaca
     1561 agtgctgagt gatagggaca attccgataa tcggtccggt cttgtctccc aaaagcgcca
     1621 aggttttgaa aatctgatct cgttcataac cttgaggaag ctctccttct agggcattga
     1681 tttgaatccc ctgatgaggg atagctgctt tagataggat ttgttccacc aatgtttttt
     1741 tgattttaac tttttttgcc attatttata tttatcctcc aattgactca tccaaatacc
     1801 aagccagatt cccagcgcaa agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc
     1861 tgtgtattgg atactttcag cgtttcctgc atttggaatt aagatcaaaa gggtacttga
     1921 taggacgata ccgatgatga aatgatagac gcgtgagtgg tagttgttta aggcataatc
     1981 catcaatttt gaaaaaacga tgagagttgc acctgcacca attccaatcg gaaagaaggt
     2041 tcccaagaga tcaaaagttt taaaaccagt caacatagga gcatagagtc ccaaaatcaa
     2101 aagtaagttc gatgggctga ggccaggaac caagacgcca agggccaata gtgcgcctgc
     2161 taggacgaag ttaagaaagc tggcgcttaa ggttccaacg acaaaattta aggcatagag
     2221 tcctaatcca gaaatgataa aggttgtcca taaccaagct aaatcaatct tgtctcggtc
     2281 agattctcga gttgattctt tgaggaggct aggaactgta ccgataatag ctcccgcaaa
     2341 gctccataat acaaagacct gataattttc aagcaggtat tcaatcgggt aggaaaataa
     2401 gccgattccc agaagcatac cgatggcaac tggaataaag tacaaaacat tttctttaag
     2461 gtctttaaag ggatgggcca gaaagccaat cattcgttca tagattccta agattgctgc
     2521 tagaacccct ccggaaattc ccggtaggat aaatccaaga gcaattacaa tccctttaat
     2581 aacgcgtgct aaccatgaga gcatatattt cctccaacta tttctatttc aaaaaatcct
     2641 tactatattg tatcacaatc agacacaaaa agaaaaagca aatgataaac aaatgctttt
     2701 aaggttttaa aaaaagtttt cgaaaggttt cttctttatt ttttaaggga gagataacgt
     2761 tgatatctaa atcgtggtca aagccggcaa tttttccttt agatgtgtat tggtgaatat
     2821 cataatctaa atcagtttta ggactgctct ccaaaaatcc tgagtctgag ccgtaggacg
     2881 gaatccaaac agaggtaaac ttgcctgtat caatactgtg ttcttccatg aagtagacac
     2941 caacgtagat gccgatgttt ttagcaccta gtgatgctag ttttgctcga aagttttcga
     3001 caccttcgtt catattagac atggttttgt cttccacgtc aagccaatag taactagggc
     3061 tgtaaggaga ggcagcattg tagaaaactt cggcagcctt ttccatttct tggacacttt
     3121 ttccagctac ataagcgtag acagcaactg ggacattccg cttttgaagt tcagtgatat
     3181 gactcttata ggccttgtct attccattga taaatgaagc atcattttct tttgttgttt
     3241 gagcaccact gtgaacacga acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt
     3301 tgatttcctc aggacgctgc cagccagaga ggtcaataat cggtttgtct aagtgtttca
     3361 aagcctgtgc ttcaatctgt gctatattgg attttgtttt aaacgattgg ctgtcattaa
     3421 gtgggcgatt gatgattaaa atgaacatca taatcccaaa aaaactaaat aaaataagtg
     3481 gatgaatttg ttttctcata tcttataagt ctaccctaaa aatcaaaaaa aatcaaaaaa
     3541 atgggttaag gaagagactt tagagcattt tttcattcaa gagtgcggaa tgatttgaaa
     3601 tatggtataa taaaagggaa tttctacaga aaagagaaga ttatgtcaaa ttttgccatt
     3661 attttagcag cgggtaaagg gactcgcatg aaatctgatt tgccaaaagt tttgcacaag
     3721 gttgcgggta tttctatgtt ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa
     3781 aagacagtaa cagttgtagg acacaaggca gaattggttg aggaggtctt ggctggacag
     3841 acagaatttg tgactcaatc tgaacagttg ggaactggtc atgcagttat gatgacagaa
     3901 cctatcttag aaggtttgtc aggacacacc ttggtcattg caggagatac tcctttaatc
     3961 actggtgaaa gcttgaaaaa cttgattgat ttccatatca atcataaaaa tgtggccact
     4021 atcttgactg ctgaaacgga taatcctttt ggctatggac gaattgttcg taatgacaat
     4081 gctgaggttc ttcgtattgt tgagcagaag gatgctacag attttgaaaa gcaaatcaag
     4141 gaaatcaaca ctggaacata cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat
     4201 atcaatacca ataacgctca aggcgaatac tatattacag acgtcattgg tattttccgt
     4261 gaaactggtg aaaaagttgg cgcttatact ttgaaagatt ttgatgaaag tcttggggta
     4321 aatgaccgtg tggcgcttgc gacagctgag tcagttatgc gtcgtcgcat caatcataaa
     4381 cacatggtca acggtgttag ctttgtcaat ccagaagcaa cttatatcga tattgatgtt
     4441 gagattgctc cggaagttca aatcgaagcc aatgttacct tgaaagggca aacgaaaatt
     4501 ggtgctgaga ctgttttgac aaacggtact tatgtagtgg acagcactat cggagcagga
     4561 gcggtcatta ccaattctat gattgaggaa agtagtgttg cagacggtgt gacagtcggt
     4621 ccttatgctc acattcgtcc aaattcaagt ctgggtgccc aagttcatat tggtaacttt
     4681 gttgaggtga aaggatcttc aatcggtgag aataccaagg ctggtcattt gacttatatc
     4741 ggaaactgtg aagtgggaag caacgttaat ttcggtgctg gaactattac agtcaactat
     4801 gacggcaaaa acaaatacaa gacagtcatt ggagacaatg tctttgttgg ttcaaattca
     4861 accattattg caccagtaga acttggtgac aattccctcg ttggtgctgg ttcaactatt
     4921 actaaagacg tgccagcaga tgctattgct attggtcgcg gtcgtcagat caataaagac
     4981 gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt aggagcctat catggagttt
     5041 gaagaaaaaa cgcttagccg aaaagaaatc tatcaaggac caatatttaa actggtccaa
     5101 gatcaggttg aattaccaga aggcaaggga actgcccgac gggatttgat tttccacaat
     5161 ggggctgtct gtgttttagc agtaacggat gaacaaaaac ttatcttggt caagcagtac
     5221 cgcaaagcta tcgaggctgt ctcttacgaa attccagccg gaaaattgga agtaggagaa
     5281 aacacagccc ctgtggcagc tgcccttcgt gaattagagg aagaaacagc ctatacaggg
     5341 aaattagaac tcttgtacga tttttattca gctattggct tttgtaatga gaagttaaaa
     5401 ctatatttag caagcgattt gacaaaagtg gaaaatccgc gtccgcagga tgaggatgaa
     5461 accttggaag tccttgaagt gagcttagaa gaagcgaaag aattaatcca atcaggtcat
     5521 atctgtgatg ccaagacaat tatggctgtt cagtattggg agttgcagaa aaaatagagg
     5581 aggtcagtat gggtaaatct ttattaacgg atgaaatgat tgaaagagct aatagaggcg
     5641 aaaaaatttc aggtcctcct ttgctagatg ataatgagga aactaagatt ttaccaacct
     5701 cttcttcccg ttttggttat gccaatccta aggatcatgg ttttagccag gaaaccttga
     5761 agattcaggt cgaaccatct attcataaaa gccgtcgtat tgaaaatacc aagagaaatg
     5821 tcttcaattc taagttgaat aaaatcttat ttgcggccat ctttctcttg attttgcttg
     5881 ttttagcaat gaaacttttg taatagaaaa ggaattgaaa tgaaaatagg aattattgct
     5941 gctatgccag aagaactggc ttatctggtc cagcatttag ataataccca ggagcaagtt
     6001 gttttgggga atacctatca tacaggaacc attgcttctc atgaagtcgt tcttgtagaa
     6061 agtggaattg gtaaggtcat gtctgctatg agtgtggcga ttttggctga tcatttccag
     6121 gtggatgccc ttattaatac gggttcagct ggggcagtag cagaaggtat cgctgttggg
     6181 gatgtcgtga ttgctgacaa attagcctat catgacgtgg atgtcacagc ttttggctat
     6241 gcttatggac aaatggcgca acaaccgctt tatttcgaat cagacaaaac ctttgttgct
     6301 caaatccaag agagtttatc tcaattggac caaaactggc atcttggttt gattgctaca
     6361 ggagatagtt ttgttgcagg aaatgacaag atagaagcga ttaagtccca tttcccagaa
     6421 gttttagccg tggagatgga gggggcagct attgctcaag cagcgcatgc cctcaatctc
     6481 ccagtcttag tcatcagagc tatgagtgac aatgccaacc atgaagcaaa catctttttt
     6541 gatgagttta ttatcgaagc tggacgtcgc tctgcccaag tcttgttgac ctttttgaag
     6601 gctttagatt aagcggaaat ttgacagttt ttctagctta tgataagatt taagtaaaga
     6661 aaagctagaa aacgtttcag aggatattat gagtattgaa atgaccgtca gtgagattgc
     6721 agaggtctta ggattatctc gccaagcaat caataaccgt gtcaaagaat taccagaaga
     6781 agacacagat aaaaatgaca aaggggtaac agttgttacc agaagtggct tgattaagct
     6841 agaagaaatc tataaaaaaa cgatttttga agatgagcct gtcagtgaag atgtcaaaca
     6901 acgtgaactg atggagattc tagtggatga gaagaatgca gaaattcttc gtctttatga
     6961 acaattaaaa gccaaggatc gtcagttatc agaaaaagac gagcagatgc gtatcaaaga
     7021 ccgtcagatt gctgagaaag acaaacaatt agatcagcaa caacaattga cccttcaagc
     7081 catgaaggat caagaaaatc ttaagctaga gctggaccaa gcaaaagaag aagtccaatc
     7141 cactaagaaa ggcttttttg ctcgtttatt tggaggataa tcaaggagct gtttaggtta
     7201 aatgctaacc tgatggcttc ttttgtttgt gaatagtata gttgattaga acagagacag
     7261 tagaggagag gtacagaatg gaacgattag aagattacat tgcttttgac ttagaattta
     7321 atcagcacga aggacaaaca cacttgattc aagtatcggc agtgcgtttt agagatggtc
     7381 gggaaatcga tgcctatgat tcctatgttc ataccagcgt ccctctaaaa agctttatca
     7441 atggtttgac cgggattaca gctgagacct taaaagatgc tcctccagtt gagaaagtct
     7501 tagaagaatt ccaagagttt gtgggttctt tgctgatgat aggctacaat gctgctaaaa
     7561 gtgatttacc tattttagca gatcatggtt tagactatag ccaacagtac aaggtggatt
     7621 tgtatgatga agcttttgaa cgtcggagtt cagatttaca tggtattgcc aatctcaaat
     7681 tgcaaactgt tgcctcattt cttggatttc aaggtcagtc tcataatagt ttagaggatg
     7741 ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc ggatcaagct agggaattgt
     7801 tagagacaga aagtagctta tcaaacaatc cttttggtgt cttggacttg tctcaattat
     7861 ttgactagga gtgcctatga aacctgaaaa acctaaaaaa ttgggtctta aacagattta
     7921 cctcaatctt gataaaatcc tctttctatt tttcttgatt tttatgatag tggagtattt
     7981 gtgggtacca ttcaattcat ggttggctag cttcttatta gatcagacag gttatctttt
     8041 tatttcctat aacaatgtct tagccatcct tactcattct ccattgatta gtctagcttt
     8101 tttagccttg attgtaatta accttctggt tgcttatttt caaataggac tcctctttat
     8161 tggtgctcgt catctcctct ataatgaaaa gcgaaggcta attgagtata tccgcaaggt
     8221 tttccatgaa agttttggat ttatgaaaaa gctaacttgc gctaaagcct tgtttatctt
     8281 tttctatata gctatgcttt ttccttttat acggaaaatg ctgaagattt attatcttaa
     8341 taaaatcgtc attccagagt ttatccaagc ttatttagaa gataaatatt ggatgtggtg
     8401 gctgagcatc ctacttctat ctcttatctt tctctatgtc tctgtcagat tgatgtttgc
     8461 ccttccgaag attgtatatg atcagctgac tgttcgagaa gcagtgatgt ttagcttgga
     8521 gaaaaccaag aagagagtta ctttttatgc ttggaattta ttttacatct tgctcaaagc
     8581 acatttatta ttttatcttc ctttgattcc tttattattg gctcaaactt tggtagatga
     8641 tatcactcag agagagtctc tgattcttgg tattttgaat tttgtcgtga ttaaaaatct
     8701 ctattatatg gctctgactt attttttggt taaatttgtt tcatttttga caggaaagga
     8761 gctggatatg cttcctagga gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg
     8821 tgccagtctt ttctttgcct tagaaggtta tatttatctg gaggctccca tggttcatct
     8881 acctcaactt atttctcacc gaggggtttc caatgcaaat gggattcaaa atacagtaga
     8941 gtccttggaa actacagcac aactcaaacc agacttggtg gagacggacg tgcaggaaac
     9001 aaaagatggg cagtttgtca tgatgcatga tgctaacttg aaaaatctag caggtatcaa
     9061 taaaagtcct caagacttaa acttggagga gcttaaaggg attgatattt ttgaaaatgg
     9121 ctaccagact aaaatttcaa gctttgaaga ttatctcagt cgagccaacg aacttggtca
     9181 aaaattacta attgaaatta aaaccagtaa aaaagatagt ccagacatga tgaaccgctt
     9241 tttagcccgt tatgctgcaa agctcaagat ttatggacat caaatccagt ctttagacta
     9301 ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg ccagtttatt tcatcatgcc
     9361 ctacaattct gtctttccta aaacaagagc gacaggatat actatggagt actcaacctt
     9421 ggatgaatat tttgtaagca aactatggac aacggatcag aaactttatg tctggactgt
     9481 caatgattca gaagctatca gcaaatctct tcacttagga gtagatggag tgattacaga
     9541 tgatttggaa aaagttcagc gggaaataga agtagcccaa gaagatccag aatatacgga
     9601 tttgctcttg aaaaaagcat tggaattctt tgaattttag taataaaaaa gaggaacggt
     9661 tgttcctccc atgataggta agtattcttg tgaatgcttg cttttttgtg gttgcaatcc
     9721 gtttacgaga attgtttgta ttgttcttgt ttcaatttac tttatagtgc tttgaagttg
     9781 gaatgctaca ctataacttc taaaatatag taaaatgaac caaaaatagt acacaatgtg
     9841 gtataat
//
LOCUS       DAVLBN010000068         9844 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLBN010000068 DAVLBN010000000
VERSION     DAVLBN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.068"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..220
                     /locus_tag="VXC24_001821"
     CDS             <1..220
                     /locus_tag="VXC24_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV0493895.1"
                     /translation="GSWYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKW
                     YYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(450..1430)
                     /gene="dusB"
                     /locus_tag="VXC24_001822"
     CDS             complement(450..1430)
                     /gene="dusB"
                     /locus_tag="VXC24_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0493896.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1417..2289)
                     /gene="hslO"
                     /locus_tag="VXC24_001823"
     CDS             complement(1417..2289)
                     /gene="hslO"
                     /locus_tag="VXC24_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0493897.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2454..3881
                     /locus_tag="VXC24_001824"
     CDS             2454..3881
                     /locus_tag="VXC24_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0493898.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4040..5548
                     /gene="glpK"
                     /locus_tag="VXC24_001825"
     CDS             4040..5548
                     /gene="glpK"
                     /locus_tag="VXC24_001825"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0493899.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5590..7416
                     /gene="glpO"
                     /locus_tag="VXC24_001826"
     CDS             5590..7416
                     /gene="glpO"
                     /locus_tag="VXC24_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0493900.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7486..8190
                     /locus_tag="VXC24_001827"
     CDS             7486..8190
                     /locus_tag="VXC24_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0493901.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8487..8690
                     /locus_tag="VXC24_001828"
     CDS             8487..8690
                     /locus_tag="VXC24_001828"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493902.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8777..9385)
                     /locus_tag="VXC24_001829"
     CDS             complement(8777..9385)
                     /locus_tag="VXC24_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493903.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2840 a         1950 c         2250 g         2804 t
ORIGIN      
        1 tggctcatgg tactacctaa acgctaatgg tgatatggcg acaggttggg tgaaagatgg
       61 agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat ggttcaaagt
      121 atcagataaa tggtactatg tcaatggctc aggtgccctt gcagtcaaca caactgtaga
      181 tggctatgga gtcaatgcca atggtgaatg ggtaaactaa acctaatata actagttaat
      241 actgacttcc tgtaagaact ctttaaagta ttccctacaa ataccatatc ctttcagtag
      301 ataatatacc cttgtaggaa gtttagatta aaaaataact ctgtaatctc tagccggatt
      361 tatagcgcta gagactacgg agtttttttg atgaggaaag aatggcggca ttcaagaggc
      421 tctttaagag agttacgggt tttaaactat taagccttct ccaattgcaa gagggcttca
      481 atctctgcca gggtgctagc ttgcgaaatg gctccacgga gtttggcagc gccagatgtt
      541 ccacggaggt agtgaggagc gaggccgcgg aattcacgaa ctgcgacgtt ttctcctttg
      601 aggttaatca atcgtttcaa gtgttcgtag gcgatcttca tcttgtcttc aaaggtcaaa
      661 tcaggtagga tttctcctgt ttcaaagtaa tggttgattt ggttgaagag gtaaggattt
      721 cccatggcag ctcggccaat catgactgcg tcagcaccaa cttcttcgat gcgttgcttg
      781 gcttcttgga cagtacggat atcaccgttg gcgatgaatg gaatcttggt tagagcttgg
      841 gcaaccttgt aaagggtctc aaggtctgcg tggccagtat acatttgttc acgggtacgg
      901 ccatgcatgg cgagggcaga aacacctgca gcctcagcag cgagggcatt ttctactgcc
      961 agagatgggt ccgcccagcc ggtacgcatt ttgacagtaa gtgggatatc aaggacagac
     1021 tggaccttgt tgatgataga gtagatcttg tcaggatcct tgagccacat agctccagct
     1081 tcgttcttca cgattttgtt gacagggcag cccatgttga tatcgacgat atcggtcttg
     1141 gtgttttctt ggatgaattc tgctgcgcgt gctaggctgt cttcatcgct accaaaaagt
     1201 tggatagaga cagggttttc gccctcatcg atatgaagca tgtgcagggt tttttcgttg
     1261 ttgtattgga ttcccttgtc agagaccatt tccattacaa cgagtccagc tccgagctct
     1321 tttgcgatgg tacgaaaggc tgagttggtc acgccagcca taggcgctaa aacggtacga
     1381 ttgggaatct caatattgcc aatcataaaa ggtgtattaa gatttgtcac gaatgagttc
     1441 ctccaggtcc ttttcatcaa agttgtaagt agtttggcag aattgacaag tgatttctgc
     1501 cccgtggtct tcctctttca tttcctgtaa gtctgagctt ggaaggctgg caagagcgtt
     1561 cataaagcgt tcatggctac agtcacattg gaaacggatt tcttcttcag aaagacgctt
     1621 gtaggcttcg tccccgtaga tagccttgag gagggcttcg atatggtcgt cgctttcgag
     1681 aagagtagag atagctggca tttcttggat gcgtttttca aagcgagcaa tctcttcttt
     1741 cttggctcct ggcaagactt gaactaggaa accacctgca accttgacct tgtcttcctc
     1801 gtccaaaagg acattgaggc cgaccgctga aggcgtttgt tggctttcag taaggtaaaa
     1861 ggcaaggtct tcaccgattt ctccagagat gaggggagtt atagagttgt aaggatttcc
     1921 agcaccgtag tctgtgataa cgaggaattg accatttcca acaaaaggtc cgactaggac
     1981 ttcaccagtc gcagtctttt tgatgtcaac accaggattt tgaacatagc ctttgacgtt
     2041 ccccttggta tcagcgacgg tgataatagc acctagagag ctagagccca acaccttaac
     2101 tgtaagtttg gtatttcctt tttcattggc tgcgagaatc tggctggcga taagagttcg
     2161 accaagcgct acagttgagc tagcttgggt ttgatgtttt tcttgagcag tgcggacggt
     2221 ttccgtgcta tcaaggacaa aagcacgaaa ggctccgctt tctgatatag ttttaataat
     2281 tttatccata gctactattt tagcataaaa atgcccaaag ggggagccgt gtgtttactg
     2341 attttcagga taatggacca ggaaatcagc atgaaaataa aaagagaaac agattatttc
     2401 agcatttgta agatttatgc tatgcttaag gtagaaaatg aaaggggtaa caaatgtatt
     2461 taggagattt gatggagaaa gccgagtgtg gtcaattttc aatcctttcc tttctattac
     2521 aagagtctca gacgaccgtc aaggctgtaa tggaagaaac aggattttca aaagcaaccc
     2581 taaccaaata tgtcaccctg ctcaatgaca aggctttgga tagtggctta gagctggcta
     2641 ttcactcaga agatgaaaat ctgcgtctgt ctatcggtgc agctaccaag gggagagata
     2701 ttcggagctt gtttttggag agtgctgtta aataccagat tttggtttat cttctctacc
     2761 accaacagtt tttagcccat cagctggctc aagaattggt gattagcgag gctacgcttg
     2821 gtcgtcactt ggctggttta aatcagattt tgtcagaatt tgatttatcc atccaaaatg
     2881 gacgttggcg aggtccagag catcagattc gctatttcta tttctgtctt ttccgaaagg
     2941 tctggtcgag tcaggaatgg gaaggtcaca tgcagaaacc agagagaaaa caggagattg
     3001 ccaatttaga ggaaatctgc ggtgcaagtt tgtctgtggg gcagaaattg gacttggttc
     3061 tctgggctca catcagtcaa caacgtcttc gggtcaatgc ttgtcagttt caagtcatag
     3121 aagagaaaat gcgagggtat tttgacaata ttttctacct tcgtttgctg agaaaggttc
     3181 cgtccttttt tgctgggcaa catattccac taggagttga ggatggtgag atgatgatat
     3241 tcttctcttt tctcctatct catcgcattc ttcctcttca tactatggag tatattcttg
     3301 gttttggagg gcagttggca gatttactga cgcaattgat tcaagaaatg aagaaggagg
     3361 aactattggg ggattataca gaggaccatg tcacctatga actcagtcag ctttgtgctc
     3421 aagtctatct ctataagggc tatattttac aggatcgcta caagtaccag ttagagaatc
     3481 gtcatccata tttactgatg gaacatgatt ttaaagagac agcagaggag atttttcatg
     3541 ctctacctgc ttttcaacag gggacagatt tagataagaa gattctctgg gaatggctcc
     3601 agttaatcga atatatggct gaaaacggtg gccagcatat gcggattggt ctggatttga
     3661 catctggttt tcttgtcttt tcaaggatgg cagccatttt gaaacggtat ttggaataca
     3721 atcgttttat taccattgaa gcttatgacc ctagtcggca ttatgatttg ctggttacca
     3781 ataacccgat tcataagaag gaacagacac cagtctatta tttaaaaaac gacttggata
     3841 tggaagattt ggcagggatt cgtcagttat tattcactta aaaggcttgg ttaatccagg
     3901 tcttttttgt gaaattcaca caatctcctc acattttttt aaaaattaaa aaaagttgat
     3961 aaacaagaaa gcgctttatt ttgtatacta gtaagtgtaa agaggaaaca cctcaagatc
     4021 tttatcagga ggacagtaca tgtcacaaga aaaatacatc atggccattg accagggaac
     4081 tacaagttct cgtgccatca ttttcaacaa aaaaggggaa aaggttagct cgagtcaaaa
     4141 agagtttacc cagattttcc ctcaggcagg ttgggttgag cacaatgcca atgaaatttg
     4201 gaactctgtt cagtcagtta ttgcgggtgc tttcatcgaa agtggtgtca agccaaatca
     4261 aatcgaggca atcgggatta ccaaccaacg tgaaacaacg gttgtctggg ataagaaaac
     4321 aggacttcct atctacaatg ctatcgtttg gcagtcacgc cagacagcac ctttggctga
     4381 gcaactaaaa agccaaggtt atgtggaaaa attccatgaa aagactggtt tgattattga
     4441 tgcttacttc tctgctacca aggttcgttg gattttggat catgtagaag gtgctcaaga
     4501 gcgagcagaa aaaggggaat tgctctttgg tactatcgat acttggttgg tttggaaatt
     4561 gactgacggt gcggctcacg tgactgacta ctcaaatgca gctcgtacca tgctttataa
     4621 cattaaagaa ctcaaatggg atgatgagat tttggaaatc cttaacattc cgaaggctat
     4681 acttccagaa gttcgttcta actccgaaat ctacggcaag acagctccat tccatttcta
     4741 cggtggagag gtgccaatct caggtatggc tggggaccaa caagcagccc tctttggaca
     4801 gttggctttt gagccaggta tggttaagaa tacttatgga acaggctctt tcatcatcat
     4861 gaatactggg gaagagatgc agttgtctga aaacaacctc ttgacaacca ttggttacgg
     4921 aatcaacggt aaggtttatt atgccttgga aggttctatc ttcatcgcag gaagtgctat
     4981 tcagtggctt cgtgacggtc ttcgcatggt tgaaaattca ccagaatctg aaaaatacgc
     5041 tcgtgattct cacaacaacg atgaagttta tgtcgttcca gcctttacag gtctaggcgc
     5101 tccatactgg aaccaaaatg ctcgtggttc cgtctttggt ttgactcgtg gaacaagcaa
     5161 agaagacttt atcaaggcga ctttgcaatc tattgcttat caagtgcgtg acatcatcga
     5221 caccatgcaa gtggatactc agaccgccat tcaagtactg aaggtggatg gtggtgcagc
     5281 catgaacaac ttcctcatgc agttccaggc ggatatttta ggcattgata ttgcacgtgc
     5341 taaaaacttg gaaacaacag ctctaggagc ggccttccta gcaggtttat cagtagggta
     5401 ttggaaagac ttggacgagt tgaaactctt gaacgagaca ggagaactct ttgagccatc
     5461 tatgaacgaa tctcgcaagg aacaactcta caagggctgg aagaaggctg tgaaagcaac
     5521 tcaagtcttt gcggaagtag acgactaata ctggcagaat aaagcgattt atttagaaag
     5581 tgtgtaaata tggaattttc aaagaaaaca cgtgaattgt caattaaaaa aatgcaggaa
     5641 cgcaccctgg acctcttgat tatcggtgga ggaatcacag gagctggtgt agccttgcag
     5701 gcggcagcta gcggtcttga gactggtttg attgaaatgc aagactttgc agaaggaaca
     5761 tctagtcgtt caacaaaatt ggttcacgga ggacttcgtt acctcaaaca atttgacgta
     5821 gaagtggtct cagatacggt ttctgaacgt gcagtggttc aacaaatcgc tccacacatt
     5881 ccaaaaccag acccaatgct cttaccagtt tacgatgaag atggagcaac ctttagcctc
     5941 ttccgtctca aagtagccat ggacttgtac gaccttttgg caggtgttag caacacacca
     6001 actgcgaaca aggttttgag caagaaagaa gtcttggaac gccagccaaa cttgaagaag
     6061 gaaggcttgg taggaggtgg agtgtatctt gacttccgta acaacgatgc gcgtctcgtg
     6121 attgaaaaca tcaaacgtgc caaccaagac ggtgccctca ttgccaacca cgtgaaggca
     6181 gaaggcttcc tctttgacga aagtggcaag attacaggtg ttgtagctcg tgatctcttg
     6241 acagaccaag tatttgaaat caaggcccgt ctggttatta atacaacagg tccttggagt
     6301 gataaagtac gtaatttgtc taataaggga acgcaattct cacaaatgcg cccaactaag
     6361 ggagttcact tggtagtgga ttcaagcaaa atcaaggttt cacagccagt ttacttcgac
     6421 acaggtttgg gtgacggtcg tatggtcttt gttctcccac gtgaaaacaa gacttacttt
     6481 ggtacaactg atacagacta cacaggtgat ttggagcatc caaaagtaac tcaagaagat
     6541 gtagattatc tacttggcat tgtcaacaac cgctttccag aatccaacat caccattgat
     6601 gatatcgaaa gcagctgggc aggtcttcgt ccattgattg cagggaacag tgcctctgac
     6661 tataatggtg gaaataacgg taccatcagt gatgaaagct ttgacaactt gattgcgact
     6721 gttgaatctt atctctccaa agaaaaaaca cgtgaagatg ttgagtctgc tgtcagcaag
     6781 cttgaaagta gcacatctga gaaatatttg gatccatctg cagtttctcg tgggtctagc
     6841 ttggaccgtg atgacaatgg tcttttgact cttgctggcg gtaaaatcac agactaccgt
     6901 aagatggctg aaggagctat ggagcgcgtg gttgacatcc tcaaagcaga atttgaccgt
     6961 agctttaaat tgatcaattc taaaacttac cctgtttcag gtggagaatt gaacccagca
     7021 aatgtggatt cagaaatcga agcctttgcg caacttggag tatcacgtgg tttggatagc
     7081 aaggaagctc actatctggc aaatctttac ggttcaaatg caccgaaagt ctttgcactt
     7141 gctcacagct tggaacaagc gccaggactc agcttggcag ataccttgtc ccttcactat
     7201 gcaatgcgca acgagttggc tcttagccca gttgacttcc ttcttcgtcg taccaaccat
     7261 atgctcttta tgcgtgatag cttggatagc atcgttgagc cagttttgga tgaaatggga
     7321 cgattctatg actggacaga agaagaaaaa gcaacttacc gtgctgatgt cgaagcagct
     7381 ctcgctaaca acgatttagc agaattaaaa aattaagaaa aaataaaaga ggtggagggc
     7441 agcattcctt gtcgcccgtc ccttcttttt aatggagaca gaaagatgat gaatgaatta
     7501 tttggagaat ttctagggac tttaatcctg attcttctag gaaatggtgt tgttgcaggt
     7561 gtggttcttc ctaaaaccaa gagcaatagc tcaggttgga ttgtgattac tatgggttgg
     7621 gggattgcag ttgcggttgc agtctttgta tctggcaagc tcagtccagc tcatttaaat
     7681 ccagctgtga cagttggtgt agctttaaaa ggtgacttgc cttgggcttc cgttttgcct
     7741 tatatcttag cccagttcgc aggggccatg ctgggtcaga ttttggtttg gttgcaattc
     7801 aaacctcact atgaggcaga agaaaatgca ggcaatatcc tggcaacctt cagtactgga
     7861 ccagccatca aggatactgt atcaaacttg attagcgaaa tccttggaac ctttgttttg
     7921 gtgttgacaa tctttgcttt gggtctttac gattttcagg caggtatcgg aacctttgca
     7981 gtgggaactt tgattgtcgg tatcggtcta tcactaggtg ggacaacagg ttatgccttg
     8041 aacccagctc gtgaccttgg acctcgtatc atgcacagca tcttgccaat tccaaacaag
     8101 ggagacggag actggtctta cgcttggatt cctgttgtag gccctgttat cggagcagcc
     8161 ttggcagtgc ttgtattctc acttttctag tttatactct tcgaaaatca aattcaaacc
     8221 acgtcagcgt cgccttaccg tactcaagta cagcttgcgg ctagcttcct agtttgctct
     8281 ttgattttca ttgagtatta gaaaacaatt atgttgatag agcttgggca agagcccaat
     8341 ttcagcaaaa aatgaagtaa atcttctcat aataaaacgc atcatatcaa gcacgaaaat
     8401 tccacgaggt caactacagt cagaaagctg aacaacaagc caaaacgccc aaaaaaggcg
     8461 gcaaaaagca agcacctgca agcaacgtgc cgaaatggtc aaatcctgat tatgtcaacg
     8521 aattagaccc aaaaatcgtt gatatgctag tagaatttca caagtcacaa ggcactttgg
     8581 aaactcccga ggcgcaagca gaaatcgccc aaaaacgtga agaaatcgag caaaggagag
     8641 ctgagcttga gggtaaaaaa caagagcttt tgaaccgctt gaacaaatag agtttcgcaa
     8701 gtattatgct tacaaattac ttgagcaatt aactaaaata taaactctgc ctagatataa
     8761 aggcagggtt tatattttag aaattcacgt aggttgttac ggtttttaca tacccagtat
     8821 agtttgagtt tctatagtat tcagtgataa acttccattt tctttgagca acatggatat
     8881 aagtacttgt tatgtagtat ggatatgggc tttgtgaatc caagtaagac tgataagctt
     8941 gtataccaaa atatgctcca ccaattattg caccccatgg accccccaat aaagcaccta
     9001 tcctaccaat catataactg attccagcac cagtcatgaa gttagcgaat gtgttagctt
     9061 gtttattccc atgtattgtg ttgacgtaat tccaaacatt aggatcgtat gatctaaaag
     9121 atatatttag gtcgatttca ttcttttgat aagccatata aaatgcccca ttgatataga
     9181 cgccgtcagc acgtcgttca atagtgtcta cacttccatc tggattgaca acctcaagaa
     9241 cttcatcgct taaaatattt acttgcgtat ctccgaaccg cactgatgag ccattctcaa
     9301 actgagcctc accagataca actttagagt ttgccgataa gctatcatca gcaaaaacaa
     9361 caagcgacgg ggaaatgcta gacatacaga aaacagacat aactagcaaa cacatgcatt
     9421 taaacatctt agacataacg gaaactcttt tgtatttttg atttttttca acttttatta
     9481 tacaataaaa ccaaataaaa agaaagcggt aacaatatgc ttaatgcgaa aattttttat
     9541 atatttttat gtttgatcgt tatcgaaact acaggcttgt tgttgttgaa aagaggtctc
     9601 gaaatgggtt atttagacac agaagctatt atcctcgcag ttttttcatt tgctttttac
     9661 aacctatgtt cattcgcttg ggtctgctct acaataaaaa acaataaaaa ataaatagac
     9721 gtattttcaa aaaaaaaaaa aaaatgcata tttatattag caaaatgacg atttaaatcg
     9781 tcgttttttt gtagtacgac gggcatgtcg tatatctgag gtgtaagtcc tcggtgggca
     9841 cctg
//
LOCUS       DAVLBN010000069         9246 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLBN010000069 DAVLBN010000000
VERSION     DAVLBN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.069"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            342..1385
                     /locus_tag="VXC24_001830"
     CDS             342..1385
                     /locus_tag="VXC24_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0493904.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1552..3639
                     /gene="topA"
                     /locus_tag="VXC24_001831"
     CDS             1552..3639
                     /gene="topA"
                     /locus_tag="VXC24_001831"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0493905.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3745..4104
                     /locus_tag="VXC24_001832"
     CDS             3745..4104
                     /locus_tag="VXC24_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0493906.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4197..4829
                     /locus_tag="VXC24_001833"
     CDS             4197..4829
                     /locus_tag="VXC24_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0493907.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4873..5529
                     /locus_tag="VXC24_001834"
     CDS             4873..5529
                     /locus_tag="VXC24_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0493908.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5548..6168
                     /locus_tag="VXC24_001835"
                     /pseudo
     CDS             5548..6168
                     /locus_tag="VXC24_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6196..6630
                     /locus_tag="VXC24_001836"
     CDS             6196..6630
                     /locus_tag="VXC24_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV0493909.1"
                     /translation="MVAGSMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6642..7679
                     /gene="leuB"
                     /locus_tag="VXC24_001837"
     CDS             6642..7679
                     /gene="leuB"
                     /locus_tag="VXC24_001837"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0493910.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7676..7945
                     /locus_tag="VXC24_001838"
     CDS             7676..7945
                     /locus_tag="VXC24_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0493911.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7949..8308
                     /gene="leuD"
                     /locus_tag="VXC24_001839"
     CDS             7949..8308
                     /gene="leuD"
                     /locus_tag="VXC24_001839"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0493912.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8527..8670
                     /locus_tag="VXC24_001840"
     CDS             8527..8670
                     /locus_tag="VXC24_001840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493913.1"
                     /translation="MTSDKAGLERKFAAKEGKRNKPGVVLCGSMDELCALAQLNPKIE
                     AFY"
     gene            8689..8943
                     /locus_tag="VXC24_001841"
     CDS             8689..8943
                     /locus_tag="VXC24_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493914.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            8933..9094
                     /locus_tag="VXC24_001842"
     CDS             8933..9094
                     /locus_tag="VXC24_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493915.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNL
                     WDYRQVEYY"
BASE COUNT         2856 a         1629 c         2054 g         2707 t
ORIGIN      
        1 tagagattac aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata aaaataaaat
       61 ggttattata aaaaatggtc tgaaatagat gatgatactt ttcgaaaatc tttttacatc
      121 agctcagctt tgccttgctg tgttttgagc aagctacggt tagcttccga gtttgatttt
      181 catttactag aaatgaaact gatgagagat atcagtagac atctgagtca ggatattatg
      241 gaaaatgata aaaagagctc gtgagattgg catatcagac tactaaagta ttgagtttgt
      301 taggatttta gcgactagtt agctgggaaa ggaagatatt tgtgacaaat aataaactgt
      361 attcgttgat agaatttaga aataaaatat atgaagaatt agaactttcc agaagtgatt
      421 tagcgatttt actatgtgcc atgcttatcg cctctatcgg attaaatatg gattcgactc
      481 ccgtgattat tggagccatg ttaatctctc ctttgatgac acctattctg ggagtggggc
      541 tctctctagc tatatttgat tttaaattgt taagaaaatc ttttaaaata ttagctattc
      601 aaattcttgc cagtctaata gcttcaacac tttattttta tctttctccc atttcgtatg
      661 ctagttcgga gattattgct agaacctctc cgactatttg ggatgttctc attgcttttg
      721 taggagggat agcaggtatt attggtgcta ggaaaaaaga gaccaataat attgttcctg
      781 gtgttgctat tgcaaccgcc ttgatgcctc ctctttgtac agtaggttat gctattgctt
      841 ctgctaatct aaaatttatc ataggctcct cttacctatt cctcatcaat tgtagcttta
      901 ttgtcattgc gacttatata ggtgttaggt tgatgatggt taagaaacat tattttaaag
      961 ataatgaaga agactctaaa atgcgtagga ttttgcttct agttgctgtt ttgctgatga
     1021 ttccgagttt catctctgca acgactttag tgagagaaac gttgaaaaaa gagtccctta
     1081 agaaatttat atcagagcag tttcaggggc ataatatttt gaaaaaaacc tattctaaaa
     1141 agactcatac cctaaagcta accatttcag gaaattattt gacagaagaa gaactcgata
     1201 tgatttcaag taagagaggt gactatggtt taagtgatgt ttctgttcaa gtttcacaat
     1261 tgtctgattc agaacaactt agtaaggaag aactggtgga gtatttcttc cagtatatca
     1321 aggataagga agcaaaagaa aaggaaaaag ctaataagtt ttatacagag tctgaggagc
     1381 aataatttct tgagaatagc tggtttttct cgtgagtctt ctatgtatat caaaggaaga
     1441 ctgaggtttt aagtataaaa cttttcttct attatagtag ctaagtcttg acagggttca
     1501 aaaaatggtt tacactttat aaagtttatt actttgaaaa ggtgtgatac tgtggctacg
     1561 gcaacaaaaa agaaaaaatc aacagttaaa aaaaatctag tcatcgtgga gtcgcctgct
     1621 aaggccaaga cgattgaaaa atatctaggc agaaactaca aggttttagc cagtgtcggg
     1681 catatccgtg atttgaagaa atccagtatg tccgttgata ttgaaaataa ttatgaaccg
     1741 caatatatca atatccgagg aaaaggccct cttatcaatg acttgaaaaa agaagctaaa
     1801 aaagctaata aagtttttct cgcgagtgac ccggaccgtg aaggagaagc gatttcttgg
     1861 catttggccc atattctcaa cttggatgaa aatgatgcca accgtgtggt cttcaatgaa
     1921 atcaccaagg atgcagtcaa aaatgctttt aaagaacctc gtaagatcga tatggacttg
     1981 gtcgatgccc aacaagctcg tcggatcttg gatcgcttgg tagggtattc gatttcgcct
     2041 attttgtgga agaaggtcaa gaagggcttg tcagcaggtc gcgttcagtc cattgccctt
     2101 aaactcatca ttgaccgtga aaatgaaatc aatgccttcc agccagaaga atactggaca
     2161 gttgatgctg tctttaaaaa gggaaccaaa caatttcatg cttccttcta tggagtagat
     2221 ggtaaaaaga tgaaactgac cagcaatgac gaagtcaagg aagtcttgtc tcgtctgact
     2281 agtaaagact tttcagtaga tcaggtggat aagaaagagc gcaagcgcaa tgctccttta
     2341 ccctatacca cttcatctat gcagatggat gctgccaata aaatcaattt ccgtactcga
     2401 aaaaccatga tggttgccca acagctctat gaaggaatta atatcggttc tggtgttcaa
     2461 ggtttgatta cctatatgcg taccgattcg actcgtatca gtcctgtagc gcaaaatgag
     2521 gcggcaagct tcattacgga tcgttttggt agtaagtatt ctaagcacgg tagcaaggtc
     2581 aaaaacgcat caggtgctca ggatgcccat gaggctattc gtccgtcaag tgtctttaat
     2641 acaccagaaa gcatcgctaa gtatctggac aaggatcagc tcaagctata tacccttatc
     2701 tggaatcgtt ttgtggctag ccagatgaca gcggccgttt ttgataccat ggctgttaaa
     2761 ttgtctcaaa aaggggttca atttgctgcc aatggtagtc aggttaagtt tgatggttat
     2821 cttgccattt ataatgattc tgacaagaat aagatgttac cggacatggt tgttggagat
     2881 gtggtcaaac aggtcaatag caaaccagag caacatttca cccaaccgcc tgcccgttat
     2941 tctgaagcaa cactgattaa aaccttagag gaaaatgggg ttggacgtcc atcaacctac
     3001 gcgccaacca ttgaaaccat tcagaaacgt tattatgttc gcctggcagc caaacgtttt
     3061 gaaccgacag agttgggaga aattgtcaat aagctcatcg ttgaatattt cccagatatc
     3121 gtaaacgtga ccttcacagc tgaaatggaa ggtaaactgg atgatgtcga agttggaaaa
     3181 gagcagtggc gacgggtcat tgatgccttt tacaaaccat tctctaaaga agttgccaag
     3241 gctgaagaag aaatggaaaa aatccagatt aaggatgaac cagctggatt tgactgtgaa
     3301 gtgtgtggca gtccaatggt cattaaactt ggtcgttttg gtaaattcta cgcttgtagc
     3361 aatttcccag attgccgtca tacccaagca atcgtgaaag agattggtgt tgagtgtcca
     3421 agctgtcatc agggacaaat tattgagcga aaaaccaagc gtaatcgcct cttctatggt
     3481 tgcaatcgct atccagaatg tgaatttacc tcttgggaca agcctgttgg tcgtgactgt
     3541 ccaaaatgtg gcaacttcct catggagaaa aaagtccgtg gtggtggcaa gcaggttgtt
     3601 tgtagcaaag gcgactacga ggaagaaaat attaaataag aggaggggcc cgaaagtaaa
     3661 tttcaggctc cttttggtta gaacttgaca aaatacatca ttttatgcga aactagaaga
     3721 agattatttt aactaggaga agttatgcgt cttatctatc tgataattgg ttttttatca
     3781 ctggccttgg ctattgttgg ggttgtttta cccttgttgc cgacaacgcc tttccttttg
     3841 ttgtctattg cttgtttctc cagaagttcc aagcgtttcg aagactggct ttatcatacc
     3901 aagctctatc aaacatatgt agctgatttt cgcgagacta agtctattac gcgtgaacga
     3961 aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa tttctattta ttttgcacct
     4021 cttttaccag tcaaaatcgg tctgggtgct ttgaccatct ttatcaccta ttatctcttc
     4081 aaggtcattc cagacaaaga ataattaaaa cagtagttat ttcccttgat aaaattgaaa
     4141 gcatattcat aacaatatga tataataaat ttgaagtaat attcaaggag aatcaaatga
     4201 tttacgaatt ttgtgctgaa aatgtgacct tgcttgaaaa agcgatgcag gctggagctc
     4261 gtcggattga actctgtgat aatctagcag ttggtgggac aacccccagc tatggagtga
     4321 ctaaggcagc ggttgaactg gcagctaact acgatacaac catcatgacc atgattcggc
     4381 cacgtggtgg tgactttgtc tataatgacc tagaaattgc tatcatgcta gaagacattc
     4441 gtttgactgc tcaggctgga agtcaagggg ttgtatttgg agttttaact gctgataaaa
     4501 agttggataa gcctaatctg gaaaagttaa ttgctgcatc aaaaggaatg gaaattgtct
     4561 ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc ggaagctatt gactggctca
     4621 gtcaagtcgg tgtcactcgt atcctaactc gtgctggtgt gtctggcgac tccttagaaa
     4681 aacgttttgt tcactatcac agaattttgg agtacgctaa aggtaaaatt gaaattctac
     4741 caggtggggg gattgacctt gacaaccgtc aaacctttat cgaccaggtg ggggtaacac
     4801 agttgcatgg tactaaggtt gttttttaaa aaatagaaag gaactgctag ctttgggtag
     4861 cagttttcac ttatgtttga aatttttaaa tcctatcaat ttaatcaaga aaaggctcat
     4921 gattatggtt ttatagaaaa tagcgaagtc tggacatata gttgccagat tttgcaaggt
     4981 gactttgtca tgactgtgtc catcactgct gataatgtga actttcaagt ctttgaccaa
     5041 gagactggcg acctctatcc tcacgtttat atggaaagca tgaggggaag ttttgtcgga
     5101 aatgtccgtg aggcttgtct ggagattctt taccagattc ggaaggcttg ttttgatgtg
     5161 caagatttta tctgtcatca gactaagcgt atcatgactc aagttcagga aaagtatgga
     5221 aaccagttgg agtatctgtg ggaaaaatcg cctgatacag ctgtattgcg ccatgaaggc
     5281 aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga ataagctgga aaagggcaga
     5341 gaaggacaag tggaagcagt caacctcaag catgaccaag tagctaattt actttcacaa
     5401 aaggggattt atccagcctt tcatatgagc aagcgctact ggattagtgt gtcccttgat
     5461 gatactttat cagatgaaga agtactggaa ttgatagaaa aaagttggaa cttaacctct
     5521 aaaaaatgaa atattttaat aattttcatg aactttcaat tagctaaata ttctttactg
     5581 aagaaatttt cagaaaatat aggatttacc acactagagg aatatggtgc atcttcaaat
     5641 acctgattga gaatgtcaag acggatcgtc agatcatcta ttcgcctcac tgtcatgatg
     5701 acctcggaat ggcagtggca aatagccttg ctgctgtcaa gaatggtgca ggacgtgttg
     5761 aagggactat caatggtatt agggagcgag ctggaaatgc tgctttggaa gaaattgcag
     5821 tggctctcaa tattcgccaa gattactacc aagtagaaac cagtattgtc ctaaatgaga
     5881 ccatcaatac gtcagaaatg gtttctcgct tctctggtat tccagttcct aaaaacaaag
     5941 ccgtcgttgg tggcaatacc ttctcccacg aatctggtat tcaccaagat ggagtcctta
     6001 aaaatcctct cacttatgag atcatcacac ctgaattggt tggtgttaag attccgcttg
     6061 ggtcgccatg cttttgttga gaaactgaga gaattggccc tagattttac agaagaggat
     6121 atcaaaccac tctttgctaa gttcaaggca ctggccgata agaagtaaga aatcacagat
     6181 gcagatattc gagctttggt agctggaagc atggttgaaa atccagaagg cttccacttt
     6241 gatgatttac aacttcaaac tcatgcagat aatgacattg aagcgctcgt tagcctagcc
     6301 aatatggatg gtgagaaagt cgaatttaat gcgacagggc aaggttccgt tgaagcaatc
     6361 tttaatgcta tcgataagtt ctttaaccaa tctgttcgtt tggtgtccta cactatcgat
     6421 gcggtaacag atggaatcga tacccaggat cgggttttgg tcactgttga aaacagagat
     6481 acagaaacca tctttaatgc agcagggctt gattttgatg tgttgaaggc ttctgctatt
     6541 gtctatataa acgctaatac ctttgttcaa aaagagaatg caggtgagat gggacgcagt
     6601 gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc tatggcaaag aaaatagtag
     6661 ctctagtagg agacggaatt ggcccagaaa tcatggaggt tggtttagaa gttctggagg
     6721 ctctagctga aaaaacaggt tttgactatg agattgacag acgaccgttc ggaggtgcag
     6781 atattgatgc agcatggcct cccttacctg atgaaaccct taaggcaagt agggaagcag
     6841 atgctatcct actagcaact atcggtagtc ctcagtatga tggagcagtg gttcgccctg
     6901 aacaaggcct gatgactctc cgtaaggaac ttaatcttta cgctaatatt cgtcctgtaa
     6961 aaatctttga cagtctcaag catttgtcac cactcaaact ggaacgaatt gctggtgtag
     7021 actttgtcgt ggtgcgtgaa ttgacaggcg ggatttactt tggagatcat attcttgaag
     7081 agcgcaatgc gcgtgatatc aacgactata gctatgagga agtggagcgg attattcgca
     7141 aagcctttga aattgcaaga aatcgcagaa aaatccttac tagtatcgat aagcaaaatg
     7201 ttctagcgac ctcaaaactc tggcggaaag tagctgagga agtcgcacag gatttctcag
     7261 atgtaacctt ggaacaccag ctggtagact cagctgctat gcttatgatt accaatcctg
     7321 ctaagtttga tgttattgta acggagaatc tttttggaga tattttatct gatgaatcaa
     7381 gcgtcttatc tggtacactt ggggttatgc catcagccag tcattctgaa aatggaccaa
     7441 gtctctatga acctattcac ggttcagtac ctgatattgc aggtcaagga attgccaatc
     7501 ctatttccat gattttatca gtttccatga tgttaagaga tagtttcgga ggttatgagg
     7561 atgcagagcg tatcaaacgt gctgttgaga caagtttggc ggcaggaatt ttaacgagag
     7621 atataggagg tcaggcttca acaaaggaaa tgacggaagc tattattgca aggttatgaa
     7681 gttagacgaa aaaattactc tagtcctttt gatttggaat gtcatcattt tcttgattta
     7741 tggcattgac aaattcaagg caagaagaag agcttggcgc atcccagaga aaatcttact
     7801 cattttagcc cttacttgtg gtggttttgg ggcctggtta gctggaatca cttttcacca
     7861 caagactcga aaatggtact ttaaaacagt ttggtttctt gggatggtga ccacactagt
     7921 agccttatat tttatttgga ggtaatggat ggcagggtct tcgagggaac acgctgcttg
     7981 ggctctagcg gactatggtt ttaaggtcgt gattgcagga tctttcggtg acattcatta
     8041 caataatgaa ctcaataatg gcatgttgcc aatcgttcag cctagagagg ttagagagaa
     8101 actagcccag ctaaaaccaa ccgaccaggt aactgtggac ttggaacaac aaaaaatcat
     8161 ctcaccagtt gaagaattca ccttcgagat agatagcgag tggaaacata aactcctaaa
     8221 tagtttggat gatatcggta ttaccttgca gtatgaagag ttgattgctg cttatgaaaa
     8281 acaacgacca gcctactggc aggattagaa aaaatagaaa aggaaatata gtaaactgaa
     8341 ataagatgta aacaaatgaa ttggagctta acatccattt ccagcaattt tttagaaact
     8401 acagtggact attctggatt caacacatta taaaattatg acaaaacaca ttcacaagaa
     8461 ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt gccctactaa agttggttac
     8521 attatcatga ccagcgacaa ggcaggactt gagcgtaagt ttgcagccaa agaaggtaag
     8581 cgtaacaaac caggtgttgt tctctgcggt agcatggatg aactttgcgc tttagcgcaa
     8641 ctcaacccaa aaattgaagc attctactaa aaacattggg atgaagatat tcttcttggt
     8701 tgtatccttc cttggaaacc agaagccttt gaaaaactca aagcatacgg ggatggccgt
     8761 gaagaactta tgactgatgt acgtggtact agctgttttg ttatcaagtt tggaaaagca
     8821 ggtgaacaat tggctgccaa gctttgggaa gaaggtaaaa tggtctacgc ctcatatgct
     8881 tcaatgacaa aacgattgaa actcgctatg agagcaaggt gtaatggtgt ctatggtcga
     8941 taaggacggc aaactcatcc cagaacaagg aggagcacgt tcaacctcac cagcaccagt
     9001 tgtgatccgt aaagggcttg acattgataa aatcatgatg cacctgtcag acacctttaa
     9061 cttatgggac taccgtcagg ttgagtatta ttaggataga gaagaagtct agtgttaagg
     9121 acattacagc tcataatact aggctttttt atagaaattc ttttcttttt ctataggata
     9181 tggtattcta tgtagaaaat atatgttaat aagtaatgcc aatatttaaa catcattagt
     9241 aaaagg
//
LOCUS       DAVLBN010000070         8991 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLBN010000070 DAVLBN010000000
VERSION     DAVLBN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.070"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VXC24_001843"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VXC24_001843"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0493916.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VXC24_001844"
     CDS             1085..2809
                     /locus_tag="VXC24_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493917.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VXC24_001845"
     CDS             2811..4559
                     /locus_tag="VXC24_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493918.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4951..6210
                     /locus_tag="VXC24_001846"
     CDS             4951..6210
                     /locus_tag="VXC24_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0493919.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6286..6421
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6460..6960
                     /locus_tag="VXC24_001847"
     CDS             6460..6960
                     /locus_tag="VXC24_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0493920.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            7036..7404
                     /gene="rplL"
                     /locus_tag="VXC24_001848"
     CDS             7036..7404
                     /gene="rplL"
                     /locus_tag="VXC24_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0493921.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7651..>8991
                     /locus_tag="VXC24_001849"
     CDS             7651..>8991
                     /locus_tag="VXC24_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0493922.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVK"
BASE COUNT         2781 a         1689 c         1891 g         2630 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgatc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtaca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggctttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gtccaaggac agcagagacc gtctgacaac ttctagtttg gtcactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttgc gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ctatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttctggt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tgctcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct tgccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taaaggaacc attcgttcca acttgactct aggtttcaat caagaagtat ctgaccagaa
     2401 actctggcag gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 tttggatgcc ctagttgagg caggggggcg aaatttctca ggtggacaaa aacaaaggtt
     2521 gtctatcgcc cgagcagtct tgcgccaagc tccgtttatc atcctagatg atgcaacctc
     2581 ggcactggat accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 cacgagctta attttgatct ctcaacgaac ctcaacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 ccaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag ccgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ctagagattt gcgagagcga atcatccata
     3121 agctccatcg tttaccgatt gcttttgtag ataggcaagg tagtggagag atggttagtc
     3181 gtgtaaccac ggacatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa tgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggagtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggac ttgtctatcg
     3901 atattccagc tggtagtaag atagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagcca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggttattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa tcaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa gcacagcttt gaggttgtag ataagactga cgaagtcagc
     4741 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagctcaaa acactgtttt
     4801 gaggttgcag atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga
     4861 actgacgaag tcagtaacca cacctacggc aaagtgaatc tgaagtggtt tgaagagagt
     4921 acaacttgtc ttttagaaaa ggagcctata atgaaagtct ttcagcatgt aaatatcgtg
     4981 acttgtgatc aaaatttcca tgtttatctt gatggaatct tagcagtcaa ggattctcaa
     5041 atcgtctatg tcggtcaaga taagccagcg tttttagaac aagctgagca gattatagac
     5101 tatcagggag cttggattat gcctggtttg gtcaattgtc acacccattc tgcaatgaca
     5161 ggtctgagag ggatccgaga tgacagcaat ctccatgaat ggctcaatga ctatatctgg
     5221 ccagcagaat ctgagtttac tcccgacatg actaccaatg cggttaaaga agccctaaca
     5281 gagatgctcc agtcaggaac aacaaccttt aacgatatgt ataatcccaa tggtgtggat
     5341 atccagcaaa tttatcaggt ggtgaaaact tccaagatgc gttgttattt ttctccgact
     5401 ctcttttctt cagagacaga aacaactgct gagactataa gcagaactcg atccatcata
     5461 gatgaaatct taaaatataa aaatccaaat ttcaaggtta tggtagcacc tcattctccg
     5521 tatagctgca gtagagactt gctggaagcg agtttggaaa tggcaaaaga gctaaatatt
     5581 ccgctccatg tccatgtggc ggagaccaag gaggagtcag gaattatcct caaacgatac
     5641 ggcaaacgcc cccttgcttt tcttgaagaa ctgggttatt tagatcatcc gtccgtattt
     5701 gctcacgggg tcgaattaaa cgagagagaa attgaacgct tggcatcttc tcaagtggct
     5761 atcgcccaca atcctatcag taacctcaaa ctggcatcag gaattgctcc aattatccag
     5821 ctccaaaaag cgggagtagc agtcggaatt gcgactgact cggttgcttc caataacaat
     5881 ctagatatgt ttgaggaagg aaggactgca gctcttcttc agaagatgaa aagtggggat
     5941 gccagccagt ttccaatcga aacagctctc aaggtactga caatcgaagg ggctaaggtc
     6001 cttggaatgg aaaatcagat aggaagtctg gaagtcggca agcaagcaga ttttctggtc
     6061 attcaaccac aagggaaaat tcatctccaa cctcaggaaa atatgctgtc tcacctggtt
     6121 tatgcagtta aatctagtga tgtagatgat gtttatatcg ccggagaaca ggttgttaag
     6181 caaggtcaag tcctgacagt agaactttaa aagaaaaatt acgaaaaatt ttaaaaaaag
     6241 tttgcaaaaa tcttgcattc tttttttgac tatgctatac ttatatacgg tttaaaaaaa
     6301 ctgcctaaga cagtagggga gctcgactca taaatatcct accgaggaca aaacgtatca
     6361 tgtaaaaaga agcgtattgt actttcgtgt ctaggtttgg gcgcgttttt ctttttgaaa
     6421 aattccccaa gcaaaataat tacggaggtg aacacactaa tgagtgaagc aattattgct
     6481 aaaaaagcgg aactagttga cgtagtagct gaaaaaatga aagctgctgc atctatcgtc
     6541 gttgtagacg ctcgtggttt gacagttgag caagatacag ttcttcgtcg tgagcttcgt
     6601 ggaagcgaag ttgagtataa agttattaaa aactcaatct tgcgtcgtgc agctgaaaaa
     6661 gctggtcttg aagatcttgc atctgtattt gttggaccat ctgcagtagc attttctaat
     6721 gaagatgtta tcgcaccagc gaaaatcttg aacgactttt ctaaaaacgc tgaagcactt
     6781 gaaattaaag gtggtgcaat cgaaggcgct gtcgcatcta aagaagagat tcttgcactt
     6841 gcaactcttc caaaccgcga aggacttctt tctatgctcc tttctgtact tcaagcgcca
     6901 gtgcgcaacg ttgctcttgc agtcaaagcg gttgcagaaa gcaaagaaga cgcggcttaa
     6961 tcttaagcta cacagcgtag cctagctacg aaaaaaacta ttataaaatt taaaacttat
     7021 ttggaggaaa taacaatggc attgaacatt gaaaacatta ttgctgaaat taaagaagct
     7081 tcaatccttg aattgaacga ccttgtaaaa gctatcgaag aagaatttgg tgtaactgca
     7141 gctgctcctg tagctgttgc tgcagctgat gcagctgatg ctggtgctgc taaagattca
     7201 ttcgacgttg aattgacatc tgcaggcgac aaaaaagttg gcgttatcaa agttgtacgt
     7261 gaaatcactg gtcttggtct taaagaggct aaagaacttg ttgacggtgc accagcactt
     7321 gttaaagaag gcgttgcaac tgcagaagct gaagaaatca aagctaaatt ggaagaagct
     7381 ggagcttcag ttactcttaa ataatagagc aactacatta gtagcttaaa aacatgatta
     7441 aaccgctatt cttaggagta gcggtttttc tttttgttta aaaaggggca aactttttat
     7501 atagttgttt aggaaataaa taatttttgt ataattggtt tactactcta aattaacgta
     7561 gtacaagagt ttgttaatta aactatacct tatggttttg actagtgtga tataattatg
     7621 ttgaaatact tatctggaaa ggtttttata atgagtttaa gaaataaaat tgagcaacat
     7681 attaaagagc tagagggagg gaagtttcaa aaactaggtg acgcgtacct aagtagaaaa
     7741 tacaatttta atattgtttc attaggctca caggaaggaa cagataaaac aactaaaggg
     7801 atcccagatt cttacgctgt cgaaaatggt aaatatgttt atattatgta tggcacccat
     7861 aagtctgtaa tatctaaatt agaaggagac attcagtcag ttaagaaaaa aattttagag
     7921 gaaaatattg ctgaagataa agttgggaga cttatttgtt gtcatacttc ttcaaatata
     7981 acaattaaac aaaaagaaga tctagaaaaa atggctgagc cttatcatct agaattgatt
     8041 ggaattaatg aaattgctaa tgatcttaca aagatagatt ttcaatattt agcaaaagag
     8101 tatctatcaa tcagtgaatc tacagagcaa gtttggtcta tcaatgactt cataagaatt
     8161 catgatgaga gtaaaactaa tgctcctata tcaaatgact atattggaga tgtaagtgaa
     8221 attataaata ccattaaatc aagtgaaaaa cgaatcttct taatatctgc taagcctgga
     8281 acagggaaaa ctagattagc aattgaaatt tgctctttgc tggatcgaaa taaatataac
     8341 attatttgtg tcaagagcaa taatcaggat atttaccaag atgtaaaacg caatctaaat
     8401 ttacacaaag aaaatattgt ttttattgat gatgttaata ctacacaaaa ttatatttct
     8461 acacttgggc tactgaacac gactagtaat attcggttta ttcttacggt acgtgattat
     8521 gctaaaaaag atgtaatcaa taatattaaa gtttatgggt acaataatat tgagccagaa
     8581 cttataaaag atgataattt taaggaatta ctcaatcaat tttctcgaaa cgattttacc
     8641 aatcaagaaa ttgaacatat aaaaacgata tctaaaagca atccgcgtat tgcagtcatt
     8701 gcagcaaagt tatctagctc tcaggatttg actaatttta atgatgagat tgatatttta
     8761 aaagattact atgaagaaat tttaaataaa aacaacatta tttatgcaga acaaaagact
     8821 ctatttattt tatcttactt aaaaaagatt agactggaaa gtttagaaga gaaccaggaa
     8881 ttcaataaat tactaaaaat aactgacata acaaatactg actttaagag tgcagtggag
     8941 aagcttcatg aaagagagtt gtgtaatatt tataacgaca aaattgtaaa g
//
LOCUS       DAVLBN010000071         8957 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLBN010000071 DAVLBN010000000
VERSION     DAVLBN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.071"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            221..2008
                     /locus_tag="VXC24_001850"
     CDS             221..2008
                     /locus_tag="VXC24_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0493923.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2005..2481
                     /locus_tag="VXC24_001851"
     CDS             2005..2481
                     /locus_tag="VXC24_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0493924.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            2509..3414
                     /locus_tag="VXC24_001852"
     CDS             2509..3414
                     /locus_tag="VXC24_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0493925.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            3401..4216
                     /locus_tag="VXC24_001853"
     CDS             3401..4216
                     /locus_tag="VXC24_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0493926.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            4223..4627
                     /locus_tag="VXC24_001854"
     CDS             4223..4627
                     /locus_tag="VXC24_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0493927.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            4880..6046
                     /locus_tag="VXC24_001855"
     CDS             4880..6046
                     /locus_tag="VXC24_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0493928.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            6162..7199
                     /locus_tag="VXC24_001856"
     CDS             6162..7199
                     /locus_tag="VXC24_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0493929.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            7407..8261
                     /locus_tag="VXC24_001857"
     CDS             7407..8261
                     /locus_tag="VXC24_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0493930.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            8411..8668
                     /locus_tag="VXC24_001858"
     CDS             8411..8668
                     /locus_tag="VXC24_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0493931.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT         2558 a         1681 c         2028 g         2690 t
ORIGIN      
        1 tataaatgta ttctatacaa aattatttta ggtcctatat tccgaattta aagagcgttt
       61 gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg tataatagta aaaatgcagt
      121 aaatatcccg acaatttcta ttgacaattc aaacagattg gtttataatt aatataacaa
      181 caaatgaaag cgcaaacttt cgcggtcgga aggtagtttt atgacacgat ttgagatacg
      241 agatgatttc tatctcgatg gaaaatcatt taagatttta tctggtgcca ttcattattt
      301 tagggttcct ccagaggatt ggtatcattc gctctataac ttgaaggctc ttggttttaa
      361 tacggtagag acttatgttg cttggaattt acacgagcct cgtgaaggtg agtttcattt
      421 tgacggtgat ctggatttag agaaatttct ccaaatagcg caggatttgg gtctctacgc
      481 aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct taccagcttg
      541 gctcttgacc aagaacatgc gaattcgctc atccgaccca gcatatatcg aggcagttgg
      601 tcgctactat gatcagttat tgccaagact ggttcctcgt ttgttggaca atggtggcaa
      661 tattctcatg atgcaggttg aaaatgagta tggttcttac ggagaagata aggcttacct
      721 gagagcgatt cgacagctaa tggaagagtg tggcgtaacc tgtcccctct ttacatcaga
      781 tggtccatgg cgagctactc tgaaagctgg aaccttaatt gaagaggacc tctttgtaac
      841 aggaaacttt ggttctaagg caccttacaa cttttcgcag atgcaggaat tctttgatga
      901 acatggtaag aaatggccac tcatgtgtat ggagttctgg gatggttggt ttaatcgttg
      961 gaaagaaccg attatcacac gggatcctaa ggaattggca gatgcagttc gagaagtttt
     1021 ggaacaaggc tccatcaatc tttacatgtt ccacggtggt acaaactttg gtttcatgaa
     1081 tggttgctcg gctcgaggaa ctttggacct gccacaagtt acgtcttatg attacgatgc
     1141 ccttctggat gaagaaggaa atccaactgc taaatatctt gcagtcaaga agatgatggc
     1201 aacacatttt tcagagtatc cgcagttgga accactctac aaagagagta tggagttgga
     1261 tgctattcca ctagttgaaa aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc
     1321 tgtagaaagt ctctatcctc aaaagatgga ggagctggga caaagttatg gctacctact
     1381 ttatcgaaca gaaacaaact gggatgcaga agaagaaaga cttcgtatca ttgatggtcg
     1441 agatagggcc cagctgtatg tcgatggtca gtgggttaaa actcaatatc agacagagat
     1501 tggggaagat attttttatc aaggtaaaaa gaaagggcta tctaggttag atatcttgat
     1561 agaaaatatg gggcgtgtca actatgggca taagttctta gcggatacgc aacgtaaggg
     1621 aattcggaca ggggtctgta aggatctgca tttcttacta aactggaaac actatccact
     1681 cccactagac aatcctgaga aaattgattt ttcaaaagga tggactcaag gacaaccagc
     1741 cttttacgct tatgacttta cagtcgaaga gccaaaagat acttacctag acttgtctga
     1801 gtttggtaag ggggttgcct ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg
     1861 cccaactctc tcactttata tccctcatag ctatctcaag gaaggtgcca accgcatcat
     1921 tatctttgaa acagaaggtc aatataaaga agagattcat ttaactcgta aacctacact
     1981 aaaacatata aagggggaaa acttatgaca attgtaggat gccgtattga tggacgtttg
     2041 atccacggac aagtagccaa tctttgggct ggaaaactaa atgtttcacg cattatggtt
     2101 gtagacgacg aagttgtcaa caacgatatt gaaaagagtg gtttgaaact tgcgacacca
     2161 ccaggtgtga aattgagtat tttgccagtt gagaaagctg cagccaatat tcttgctggc
     2221 aaatacgata gccaacgtct ctttatcgtg gctcgtaaac cagaccgctt ccttggtttg
     2281 gtagaagcag gtgtaccact tgaaaccctt aatgttggga atatgtctca aacaccagaa
     2341 actcgttcta ttacacgttc tatcaacgta gtagacaagg atgtggaaga cttccacaaa
     2401 ctggcagaaa aaggtgttaa acttactgct cagatggttc caaatgatcc aatttcagac
     2461 tttttgagct tattaaaata ggaaaaaatt ttttaggagg tcattgttat gatacaatgg
     2521 tggcaaattt tacttctcac tttgtactca gcttatcaaa tctgtgatga gttgacgatc
     2581 gtttcatctg caggttcccc tgtatttgct ggtttcatta ctggtttaat catgggagat
     2641 gtgactactg gtttacttat cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc
     2701 ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac agccttctct
     2761 gtttcacaag gaattgatgc accgcttgca attactacaa tcgctgtacc agtagcagct
     2821 ctcttgactt acttcgacgt tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg
     2881 gatgctgcaa tcgaacgctt tgactataaa ggtattgaac gcaactactt gcttggtgcg
     2941 attccgtggg ctctatctcg tgcccttcca gtcttctttg cccttgcttt tggtggtgcc
     3001 tttgtacaat cagtagtaga cttcgttgaa gcctacaaat gggttgcaga tggcttgaca
     3061 ctcgcaggac gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta ccttccagtt
     3121 aaacgtaacc ttcactacct tgctatggga tttggtttga cagctatgtt gactgttctt
     3181 tactcatatg taacaggtct tggtggcgct gttgctggta tcgtaggtac tcttcctgct
     3241 gaagttgctg aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat gattggtatt
     3301 tctatcgtag gtattttcct tgcagtgctt cacttcaaaa atagccaaaa agtagctgta
     3361 gcagcacctt ctacaccatc agaaagtggg gaaatcgaag atgacgaatt ctaattacaa
     3421 acttacaaaa gaagatttta atcaaatcaa caaacgtagc ttgtttactt tccaattagg
     3481 ttggaactac gaacgtatgc aagcttctgg ttacctttac atgatcttgc ctcagttgcg
     3541 taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc atactcaatt
     3601 cttcaatact tcaccattct tccataccat tatcgctggt tttgaccttg ccatggaaga
     3661 aaaagatggt gtaggttcaa aagacgctgt taacggtatc aagacaggtt tgatgggacc
     3721 attcgctcct cttggggata caatctttgg ttcacttgta cctgctatca tggggtcagt
     3781 cgcagcaact atggctatcg ctggccaacc ttgggggatc ttcctttgga ttgcagttgc
     3841 agtagcgtat gacatcttcc gttggaaaca gttggaattt gcttacaaag aaggggttaa
     3901 ccttatcaac aacatgcaaa gtaccttgac agctttgatt gacgctgcat ctgtacttgg
     3961 tgtcttcatg atgggtgctc ttgtagcaac agtgattaac tttgaaattt cttacaagtt
     4021 gccaatcggt gaaaagatga ttgatttcca agacatcttg aaccaaatct tcccacgttt
     4081 gcttccagca atctttactg cctttatctt ctggttgctt ggtaaaaaag gtatgaactc
     4141 tactaaagct atcggtatta ttatcgtact tgctttggct ctttctgccc ttggtcactt
     4201 tgcacttgga atgtaattcc ttatgactaa atcattaatt ttggtgagcc atggtcgctt
     4261 ctgtgaggag cttagaggta gcacagaaat gattatgggc ccacaagaca acatttacac
     4321 agtagctctt cttccagaag atggcccaga agaatttact gctaaatttg aagctgttat
     4381 tgaaggattg gatgatttcc tagtctttgc ggatcttctc ggtgggacac cttgtaatgt
     4441 ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt tacgcaggga tgaatcttcc
     4501 aatggtgatt gaatttatca atgcgagcct tacaggcgca gatgcggact acaagagccg
     4561 tgctgcagaa agcattgtga aagttaatga cctgttagcg ggcttcgatg atgacgaaga
     4621 tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc cgtaggtata
     4681 tgttactgac ttcgtcagtc ttatccggca acctcaaagc ggtgctttga gcagcctgcg
     4741 gctagtttcc tacagatttt agttggaact cgattcaatt catgtgacaa cgtgaaaatc
     4801 gttagagcat tttatataga atatacatgg gaatggagct tactcccatt cccatattta
     4861 atagaaaaag aggaactcaa tgctacatta tacaaaagaa gacttgctcg aattgggtgc
     4921 agaaatcact acgcgtgaaa tctaccaaca gcctgatgta tggagagaag cttttgaatt
     4981 ttatcaagca aaacgtgaag aaattgcagc ctttctacaa gaaatcgctg ataaacatga
     5041 ctatattaag gttatcttga caggtgctgg gacttctgct tatgtgggag ataccttgct
     5101 accttacttt aaggaagtct atgacgaacg caaatggaat ttcaatgcta ttgcgacaac
     5161 agatatcgtt gccaaaccag caacctattt gaaaaaagat gtggcaactg tccttgtgtc
     5221 ttttgctcgt agtgggaact cgcctgaaag tgtggcgact gttgatttgg ccaaatcctt
     5281 ggtggatgag ctttatcaag tgacgattac ttgtgcaaca gatggtaaat tggctcttca
     5341 agctcacggt gatgaccgta atctcttgct cttgcaacca gctgtctcta atgatgctgg
     5401 atttgccatg acttctagct ttacgtctat gatgttgaca gctctcttgg tctttgatcc
     5461 tacagaattt gctgttaagt ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt
     5521 tttagacaag gtagaagatg tcaaagagct cgttgattta gactttaacc gtgtcatcta
     5581 tctaggcgct ggtcctttct ttggacttgc tcatgaagct cagctcaaga ttttggaatt
     5641 aactgctggt caagttgcga ccatgtatga aagcccagtt ggcttccgtc acggtccaaa
     5701 atctcttatc aacgacaata cagttgtttt ggtctttggt acaacgacag cctacactcg
     5761 taagtacgac ttggacttgg ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt
     5821 gcttttgagt gatcaagctt ttggtcttga aaatgtcaaa gaagtggtcc ttggttgtgg
     5881 cggtgtcttg aatgatattt accgtgtctt cccttacatc gtttatgccc aactctttgc
     5941 tctattgact tcactcaagg tagaaaataa accagataca ccgtctccta caggtacagt
     6001 aaaccgtgta gtacaaggtg tcataattca cgaatatcaa aagtaagaca gtgtttatga
     6061 attcttgaca agaggatttg taaattatca gataaaccat agattgtcag tacgctttct
     6121 atggtttgtt tgcttgagag aaatagtaaa aggagaacag aatgaaagca tacacagagc
     6181 gtgtatttgg aaatgttgag ggcgaggatg tcttggccta tcgatttgag acagacggtg
     6241 gctaccaact tgaggttatg acttatggcg cgaccatctt gcgctatgtc gcacctgaca
     6301 aggctggaaa ttttgccaat gttatcttgg gatttgatga ctttgatagt tatgtaggca
     6361 atagtcccaa gcatggagca agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct
     6421 ttgagctcaa tggtaagacc tatgaccttg aggttaataa tgctagcaac tgtaatcaca
     6481 gtggttcaac tggttgggat tccagcttgt ttgaagttga agaagtaagc gatcatggct
     6541 tgactctcta cacagagcgt acagatggga caggagggtt ccctggaaat ctcaagattt
     6601 ggatcagtta tcacttggaa gaaactggtg cctatgaaat catctacaag gtaacgaccg
     6661 atcaggatac gctggtcaat ccaaccaacc acagctattt caacttgtct ggtgatttca
     6721 cgcagacgat tgaccgtcat gtcttccaac taaacacaga gggcatttac tcaatcgctc
     6781 ctgacggtgt tcctgccaaa actccagaag ccaaccgtga tgtggtcaaa cacatctaca
     6841 atggtacctt gttgaaggat atctttgcag aagaagatga gcaaatccag ctggcatcag
     6901 gtttggatca cccatttgcc cttcctgcag gccatgacaa tgctggattc ctttatgacc
     6961 aaaattcagg tcgcttcctg cttttcaaga cagaagctcc ttgctttgtg gtctacacag
     7021 caaactttgt ggatgaaagt gtcatcatag gaggtcagcc aatgctacag cacaatggga
     7081 ttgctcttga agcgcaagct ttaccagatg ccattcacag tgaccttaaa ggccaagtca
     7141 ttcttaaagc tggtcaaacc ttcaccagta agacacgtta tgaacttgtt gtgaaataaa
     7201 aaaagctggt caaaaagtct ttaaaattaa aataacgcat attgtcaggt gatgaaaagt
     7261 ttgataatat gcgttttatt atgaaatgat ttactttatc ttatcctgaa atggtgttat
     7321 ttttgagtta tctggcttga ctttcttgat ggaaattata taatagttgt aataacaata
     7381 attacaacga gaaaagagga ccatttatga cctatgaata caagagtcac atttatttgg
     7441 cagagacagt tttaaatgta aaggatttgg ccagtcaaac agccttttat cagcaagtta
     7501 ttggtttaga aatcttatct caaactgaga cagagtccat tctaggcctt ggtggaaaag
     7561 tcttggtaca gctgattcaa gcacaagaga gcggagaagt gagggaacat tatggtcttt
     7621 accatttggc cattctcttg cccacacgca aggctttggc tgatgtcttg aaacacctga
     7681 cagatttgca aattcctctt gtcggcggtg cagaccatgg ttacagtgaa gctatttact
     7741 tggaagattt ggagggaaat ggcattgaac tctatcgaga taagccagtt tccacatgga
     7801 atattcgaga agatggacgc attatcggag tgacggaggc tcttgcggcg caggacattt
     7861 atgagttggg ggaaagagta gagcccttta tcctggcaga aggtacaaga atggggcata
     7921 ttcatctttc cgtcaaggat agtcgaaagt ccagccagtt ttatcaaaag gtgttagggc
     7981 tagagaataa attcagtgtg cctggcgcta gttggattgc ggctggagat taccatcatc
     8041 atttagcagt taacgaatgg ggaggaaaag gtctggcttc gcgtaagcaa ggcttaccag
     8101 gtttagccta ctatgtcatc gaagtcgcac ataaaaaaga actgttaacg attgcccaac
     8161 gagcacaaga agttgacgca ccaatcaaat ggatgacatc gagccaattg gaaatcacag
     8221 actcagatgg catcgtgacc cgtattcgtt tagcaaggta aaattaggaa tttttaataa
     8281 gttataagta ttgctagttt gctttttgaa cggtctttgg taacagaact gcgtgagctg
     8341 gatgggtgag aattttgaca aagaagctga ttagagatat aatgaagaaa aatcgagcaa
     8401 ggaaaaagaa atgacaaatt caaagtatat tacttgtttg aaacgttcag agggccagtt
     8461 gtgtggaatt caaaagatga ttgaaggaga tcgtgactgt gctgatattg tgacgcaact
     8521 gacagcagtg aaatctagtg tagagcgcgt gattgagatg ataattaccg aaaatcttac
     8581 tgaatgtatc aatcagccac tagatgattc tgaagctcaa aaggaacgcc tagaaaaggc
     8641 tatccgatac ttgattaaac ggaaataaat gaatgttttg agacgatatg tgcaaaggtc
     8701 tattaactat tagaatagtt taatgtgagt caaaagaagt tgtaaaaaat ctttaaaatt
     8761 aaaaaacgca tagtatcagg tattgaaatg tactgccccc caaaagttag attctttctg
     8821 tctaactttt ggggggcagt acataaaaac cttgatagta tgcgttttat tgtggggaga
     8881 cttatactct tcgaaaatct cttcaaacca cgtcagtttc accttgccgt agatatggtt
     8941 actgacttcg tcagttc
//
LOCUS       DAVLBN010000072         8953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLBN010000072 DAVLBN010000000
VERSION     DAVLBN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.072"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VXC24_001859"
     CDS             complement(298..1146)
                     /gene="dprA"
                     /locus_tag="VXC24_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0493932.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1242..1931)
                     /locus_tag="VXC24_001860"
     CDS             complement(1242..1931)
                     /locus_tag="VXC24_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0493933.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1943..2821)
                     /locus_tag="VXC24_001861"
     CDS             complement(1943..2821)
                     /locus_tag="VXC24_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0493934.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VXC24_001862"
     CDS             complement(2811..3680)
                     /gene="licA"
                     /locus_tag="VXC24_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0493935.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3697..4719)
                     /locus_tag="VXC24_001863"
     CDS             complement(3697..4719)
                     /locus_tag="VXC24_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0493936.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4724..5431)
                     /locus_tag="VXC24_001864"
     CDS             complement(4724..5431)
                     /locus_tag="VXC24_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0493937.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5767..7254
                     /gene="tacF"
                     /locus_tag="VXC24_001865"
     CDS             5767..7254
                     /gene="tacF"
                     /locus_tag="VXC24_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0493938.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7264..8067
                     /locus_tag="VXC24_001866"
     CDS             7264..8067
                     /locus_tag="VXC24_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0493939.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8069..8878
                     /locus_tag="VXC24_001867"
     CDS             8069..8878
                     /locus_tag="VXC24_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0493940.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2811 a         1802 c         1518 g         2822 t
ORIGIN      
        1 aaagcgcaaa ctaggaagct agccacaggt tgctcaaagc actgctttga ggttgtagat
       61 aagactgacg aactcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtagt
      121 ttgaagagat tttcgaagag tattatatga gaaaaatcct ctactctact aatccactta
      181 gaaaaaacgc atattagcaa gtgttaaaaa cttgctaata tgcgttttat tatggaaatg
      241 ttgggttcat tttctcttaa aattgatttt ttcttagaat tctagcttag gtcattttta
      301 aaattcaaat tccgcaagaa catcttgccc actggtgagc aattttgctc cttcttgaat
      361 caaatgatgg caaccgtctg atagtccatc taaaatgcta ccaggaatag caaagacatc
      421 gcgtccttct tccattgctc gctcacacgt aatgagacta cctgaacgca tcttagcctc
      481 tgctacaatc acaccacgac aaagtccagc aatgatgcga ttacgggcag gaaaatgaaa
      541 tttcagaggt tgttcgccag gtccatattc acttagaacc agatggtcat tgccgatgta
      601 gtcttgcaag cgtttattgg ctttaggata aaacacatcc agtcctgttc caatcactgc
      661 aatggttttt ccgccattct gaagagctgc catatgagct gctgtgtcaa tgcccttggc
      721 cagaccactg acaataacca gttcattttc caagccttga atgacttttt caactgactt
      781 agctccctgt ttgctacaag cacgactgcc cacgaccgct accttcggga atttcaggag
      841 gtcaagattt cccttgtaaa ataaaagtac aggcgcatca tatatttcac tcaaatccca
      901 aggataacag tcatctaaaa tagagaaaga tggaaatttt tgaaactctt tcgacaaatg
      961 cgcatcgtct atctgaaaat aacgttccat aaaaacggct ggattacggc aacctgatat
     1021 atctgcaata tcacccaaca aaagctcctg atcaacattt tcaccgtatt ctagcacttt
     1081 caaaatctgt tgattggtca aacctgattt ttttaactta tagatttcat agtttgtgat
     1141 tttcataaat aactccattt ctttttctac tcatctatct attcgtaaaa gttcgtaaaa
     1201 aatcaaaaaa catccgacta ttttgtcaga tgttggaatc tttaattttc gtttttaaga
     1261 atttcttcta atttacgata gtcttggaca ctatcgatct cataaatgct attgccttct
     1321 aattcttcaa catagacatc tagctctttg atattatcct taaccatatt gtcccaatag
     1381 agatcaacaa attcaccact tgcataagcc ttgtcgataa agctgacaat cttttctgca
     1441 gttggagcat cccagaagga tacaccacta aggatgcgac ctgccttgct atcaacaata
     1501 atgtcttgaa ccttgtagtc atctccatag accaagaacc attcgttggt acaatcttca
     1561 cgataaacac taaaataagt cgaacgtgtc aaatcattgc ggaacatatt tttaaagaga
     1621 taattgtcag catcaataac atagctgttg gccaattctt cttttacaag atagagagag
     1681 taaaagttat tgtagtcagc gtatttatca ttgaaaacga ggcgaacacc gtatttttct
     1741 tttaagtaat cgaattgttc tttaagataa ccaacaatga tgatgatgtc attgattcct
     1801 ttttctttga gaaactcaat ttggtattca atcaaaggtt tttgattaac ctgaaccaag
     1861 gctttagggg tattttcagt cataggacgc aagcgagttc ccaatcccgc tgctaagata
     1921 atggctttca cacgaatctc ctttattctt taataataat ataaactcca gcaatgacga
     1981 caagtgacgt cataatggtc agcatatcta gcggtgcacc caaaaaaaca actgcaaaca
     2041 agaccgtcca tactacatag ctcacgttca agcctgtagc cttggctggt tgcaagcgat
     2101 tgatagcgat ataataagcc aagtaggaaa tcatatcaaa ggctgcaaaa acaatcatga
     2161 gacctagcaa ttgtccattg gctactgcag taaatgactg atgagagaag agcacaatca
     2221 caagatagga caagaacgaa gtcacttgac ggattaagag ggcttcgatt tcactcagtt
     2281 cactttccat agcaaaggag ctaagaacac tctcacttcc ccatgcaata gcacaaacca
     2341 aagcacagag aatcccaatg tagaaggaat taacctgttc aaccttatag gtctgggcaa
     2401 taatccctcc aataatcaag acaatcccaa atacagtatt tttcgaaatc ttgtgcttca
     2461 aaaagaagaa agccaataga actgaaatcg cagggtaaat agccgataca gatgaagcta
     2521 aagaacttcc gatatactta actgcataaa gattggcctg cataccgata gggcctgcta
     2581 gcaaggctcc gatgataaca ctgacattgc gaatatttaa gaaaattgag aggcgaactt
     2641 tcccttcttt taccaagaga aaagctagta agataaagat gctcaaaaaa tcatgagctg
     2701 cagccaccac aaagggtgac aaatctgtaa aaatcgaaaa gatataagca ctaaccgtta
     2761 gacccaagcc ccagaaaata cctgagagaa ggccaaaagg aactccgttt ttacttttca
     2821 tctgaacctc cataagaagc caaaccttta acagctcttt ggtaacgatt cacaccatag
     2881 tcaccaaaat cttcaccttg ctcttcctta tagacagtcc atagactcca aatagtatct
     2941 tgtaaaattt tataaatagc aatcttttca tgagaaaccg gtgtttggtc actctcatag
     3001 tgagataaga aagtttcttc ctcttgggaa gtgaattcag actctaaaaa gagggcagcc
     3061 aaatcccaca ttggatcatt cattgatgaa tattcccagt caatcaaata aagtcgtcct
     3121 tgaggtgatt cgataaagtt ttcaggcacc aaatcgatat gacaagattt tctgtcaaca
     3181 cctaagtcag ccagtctttt ctctaaggag aagactgcat ttctaacaga ttcatagttg
     3241 gcataaggaa tttgttcttc aatcaaggat tcgtattttt tgatttcttc aaaaggagca
     3301 aattctcctc ttaattcctt agcagacgta tgaatagttt gtaatattgg agcaattttg
     3361 tcgaacttgg tcttgattga cgttgaatca agcgtaatcg cagattcgat atactcattt
     3421 actttgatac cagcttcaat atcaaaaaga taatttttta catctaagcc taaatccttt
     3481 agtagttcaa gattgtactt ttcatcttgt cgattgataa gcttttctgt ccctttacca
     3541 aagaatttaa caatgtattg cttatttgtt gttttggcca aatagttttg attggtcatt
     3601 ccacccagtt gttcaacact gaggacttcc tcttcttgac taagtaagga agaaattttt
     3661 tctttaatga ttttctccac aattaacctc cagtacttat acttcccact taaacactgt
     3721 tttaaaggct gtgtttaaat cggttgcaaa gacacgatga atatctttaa tttctcttac
     3781 aggttcttct agataaagga tatttttaag acgattggca aatttcttga cttccatcat
     3841 ttggatagca tttttaaaat caatgcgacc agaacgagat gacccaacca aaatcaagcc
     3901 cttttctaag gcatcgcgag tattgagatt gactttatat tcgctaactc ccatcatgag
     3961 aatcgttccc tgaggacgaa tgtagcgaat caagtcatta atagctggtc cagtaccatc
     4021 accaccacaa cattcaaaag catggtcaaa ggccaactct tcaggaatat tatccgtaat
     4081 atagcattct ttggcaaatg agaagagttc caacttttcc caatgacgac caataaccac
     4141 aatctctgat tctggcaaag tatagttgat aatattggca accacaaaag ctaaacttcc
     4201 atctccaata acggcgatcc gctcccgctt gctatgagca agagtcaata gacgattcat
     4261 agcgtgcatg cccacactga caaactctgt aatggctgca accgtatctt caatagcatc
     4321 ataagccacc acacgatctt tagggagaga aacaaactct ctcataaagc catcaaatcc
     4381 actagacaag aaatgggtcc ctgtcatgta gttttcatag aattcttcat cactctgcat
     4441 aggagactga ttgggaatca tgacaacttt ttgaccaacc tcgtaggttc cggtcgggtc
     4501 agaaatgacg gttccacatg actcgtgaat cattgccatt ggaagctttt tattcaaaat
     4561 cttgggatca cgttttccct gatagtaacg ctgatccgca tgacagacag ccatgtagtt
     4621 gggacggata aggatatgat tctcttggtc aatagcctct tcctgatatt tgacattgat
     4681 aaacttaggc ttagttagtt gataaatttg attaatcatt ttactagtct ttctcaatca
     4741 tactttttgc aatcttcaaa tctgttacgg ttgtaatctt cagatttgag tattcacctt
     4801 tggccaaggc cacatctttt cctttgatca caaagatttt acatgcatct gtcaagattt
     4861 ccttctcttc atcagaaaga gatccataaa ggtccatgaa gtccttgcaa cggaatgttt
     4921 gaggtgtttg tccttgataa aggtgagcac gatttggaat atctgtaata aattgaccat
     4981 tggtactttc aacgatagta tcaaccgctt ctaccactgt gtccactgcg tcatgatttt
     5041 gggcaagttg gatattgtcc tgaatcatgc gaagtgtaat aaatggacga acagaatcgt
     5101 gggtaacaac gatatcctct ggagtaagcg gacgataagc atcaatggct tcaatgattt
     5161 tcttaatact tgtattgcgg tcagcaccac cctttgtaat gatgatacgt tccttataaa
     5221 gaggaagata tttatctaca agatcttctg catgagaaac ccagtctcca tgaacaccaa
     5281 ctacaatttt ttcaatactt ggctccaaga caaatttttc aattgtatga atcaaaatag
     5341 gtcgattacc tagctctaaa aattgttttg gcaagttact gatccccatg cgtgtgccag
     5401 ttccaccggc aagaattcct gcataaatca tctattttct cctttgtctt actaaaaaaa
     5461 cttattctct ctattatacc acaatctagt cctatcataa aagaaatact ggtcctcccc
     5521 ttctagaata ggagaattat gcagttctat tattcaaaga aactagtcca tttctagtaa
     5581 tgactaggaa ttctgtagca attactaata aatggctgcg aaattttaga gtccttcaga
     5641 ataatatact ttccttaaag aaaacttaaa acttaagatt tgaaacttca aagtgattac
     5701 ttgacttact gcccttcatt tcttattagc taactttatg atataatgaa aaacgaggta
     5761 aattgaatga aaagtataaa attaaatgct ctatcttaca tgggaattcg tgtcttgaat
     5821 attatttttc ccatcctaac tggaacctat gtcgcgcgtg tcttggaccg aactgactat
     5881 ggttacttca actcagtcga cactattttg tcatttttct tgccctttgc aacttatggt
     5941 gtctataact acggtttaag ggctatcagt aatgtcaagg ataacaaaaa agatcttaac
     6001 agaacctttt ctagtctttt ttatttgtgc atcgcttgta cgattttgac cactgctgtc
     6061 tatatcctag cctatcctct cttctttatt gataatccaa tcgtcaaaaa ggtctacctt
     6121 gttatgggga ttcaactcat tgcccagatt ttttcaatcg aatgggtcaa tgaagctctg
     6181 gaaaattaca gttttctctt ttacaaaact gccttcatcc gtatcctgat gctggtctct
     6241 attttcttat ttgttaaaaa tgaacacgat attgttgtct atacacttgt gatgagttta
     6301 tcgacgctga ttaactacct gattagttat ttttggatta aaagagacat caaacttgtt
     6361 aagattcacc taagtgattt taaaccactc tttctccctc tgacagccat gttagtcttt
     6421 gccaatgcca atatgctctt cactttttta gatcgcctct tcctcgttaa aacagggatt
     6481 gatgtcaacg ttagttacta taccatagct cagcgaattg tgaccgttat agctggggtt
     6541 gtaacaggtg caattggagt gagtgtgcct cgtctcagtt actatctggg gaaaggagac
     6601 aaagaagcct atgtttctct ggttaataga ggtagtcgaa tctttaactt ctttatcatt
     6661 ccactgagtt ttggactcat ggttttagga ccaaatgcca tcctacttta cggtagtgaa
     6721 aaatatatcg gaggcggcat cttgacctct ctcttcgctt ttcgtacgat tatcctggcc
     6781 ttagatacca ttcttggttc ccaaattctc tttaccaatg gctatgaaaa acgtatcaca
     6841 gtctatacag tctttgctgg gctactcaat ttgggcttga atagtctcct ctttttcaac
     6901 catatcgtgg ttcctgaata ctacttactg acaactatgt tatcagagac ttctctactt
     6961 gttttctata ttattttcat ccatagaaaa caactcatcc acttgggaca tatctttagc
     7021 tatactgttc gatactctct cttttcactt tcctttgtag caatttattt cctgattaat
     7081 ttcgtgtatc ctgtggatat ggtcattaat ttgccatttt taattaatac tggtttgatt
     7141 gtcttgctat cagctatctc ttatattagt ctacttgtct tcacaaaaga tagcattttc
     7201 tatgaatttt taaaccatgt cctagcctta aaaaataaat tcaaaaaatc ataggagttt
     7261 aaaatgaaac aactaaccat tgaagatgcc aaacaaattg aattagaaat tttggattat
     7321 attgatactc tctgtaaaaa gcacaatatc aactatatta ttaactacgg tactctgatt
     7381 ggggcggttc gacatgaggg ctttatccct tgggacgacg atattgattt atccatgcct
     7441 agagaagact accaacgatt tattaacatt tttcaaaagg aaaaaagcaa gtataagctc
     7501 ctatccttag aaactgataa gaactacttt aacaacttta tcaagataac cgacagtacg
     7561 actaaaatta ttgatactcg aaatacaaaa acctatgagt ctggtatctt tatcgatatt
     7621 ttccctatag atcgctttga tgatcctaag gtcattgata cttgttataa actggaaagc
     7681 ttcaaactgc tgtctttcag taaacataaa aatattgtct ataaggatag ccttttaaaa
     7741 gattggatac gaacagcctt ttggttgctc cttcgaccgg tttctcctcg ttattttgca
     7801 aataaaatcg agaaagaaat tcaaaaatat agtcgtgaaa atgggcagta tatggctttt
     7861 attccttcaa aatttaagga aaaggaagtc ttcccaagtg gtacctttga taaaacaatc
     7921 gatttaccct ttgagaattt aagccttcct gcacctgaaa aatttgatac tattttgaca
     7981 caattttatg gagattatat gaccctacca ccagaagaaa aacgcttcta cagtcatgaa
     8041 tttcacgctt ataaattgga ggattaggat gcaatattta gaaaaaaaag aaattaaaga
     8101 aattcaacta gccctgctgg actatattga tgagacttgt aagaaacatg atattcctta
     8161 ttttctcagt tatggaacca tgcttggagc catccgccac aaaggtatga ttccttggga
     8221 tgatgatatt gatatttccc tttatcgtga ggattatgag cgtttactga agattattga
     8281 agaagaaaat caccctcgct acaaggttct ttcctacgat acatcttctt ggtacttcca
     8341 taatttcgca tcgattttgg acacttctac tgttatagaa gaccatgtta agtacaagcg
     8401 tcatgatacc agccttttca tcgatgtctt cccaattgat cgatttacag acttgagcat
     8461 tgtcgacaag agctataagt atgtggccct tcgtcaacta gcttatatca aaaaatcacg
     8521 agcagttcac ggtgatagca aactaaaaga ttttcttaga ttatgtagct ggtacgctct
     8581 ccgatttgtc aatcctcgct acttttacaa gaaaattgat caactagtca aaaatgctgt
     8641 aaccaacact cctcaatatg aaggaggagt tgggatcggt aaggaaggga tgaaagaaat
     8701 cttcccagtt gataccttta aagaactgat tttaactgag tttgagggcc gtatgttgcc
     8761 tgttcccaaa aaatatgacc aatttttaac ccagatgtat ggcgattata tgacaccacc
     8821 atcaaaagaa atgcaagagt ggtatagtca tagcattaaa gcttatcgca aaaactgatt
     8881 gagggggatt atacaaacta ctaagataga ggttattcaa aaacataatt ttagtagaaa
     8941 atgaaatata tat
//
LOCUS       DAVLBN010000073         8919 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLBN010000073 DAVLBN010000000
VERSION     DAVLBN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.073"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            181..978
                     /locus_tag="VXC24_001868"
     CDS             181..978
                     /locus_tag="VXC24_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEV0493941.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            996..1133
                     /locus_tag="VXC24_001869"
     CDS             996..1133
                     /locus_tag="VXC24_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493942.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            1133..1336
                     /locus_tag="VXC24_001870"
     CDS             1133..1336
                     /locus_tag="VXC24_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493943.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAVELMNDLFEERKRRFAFE
                     QENYDLKQQLAIYKEKEQGEQYV"
     gene            1329..1583
                     /locus_tag="VXC24_001871"
     CDS             1329..1583
                     /locus_tag="VXC24_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493944.1"
                     /translation="MFKALKTIKKIKQLQKEMHDASVAFLLMQDLGLVPDSEKGRTIA
                     KSFYDVSHMLKDVLGGKSVDEAMKRLNSEVKIEDVEQEDD"
     gene            1576..1719
                     /locus_tag="VXC24_001872"
     CDS             1576..1719
                     /locus_tag="VXC24_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493945.1"
                     /translation="MTRIELENRVWLLANHEEKNELLDLGLTSKARYVKRVLELGKVY
                     AHV"
     gene            1888..2073
                     /locus_tag="VXC24_001873"
     CDS             1888..2073
                     /locus_tag="VXC24_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493946.1"
                     /translation="MKKRLYYKKWKQELREAMREEIDGDYLTEKMVRKMSISDMSHYL
                     NQLALEEAGYCGTMFNY"
     gene            2091..2843
                     /gene="bet"
                     /locus_tag="VXC24_001874"
     CDS             2091..2843
                     /gene="bet"
                     /locus_tag="VXC24_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV0493947.1"
                     /translation="MTNNQLATQTKRNITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYTNRNGGKEFSLIVSKEAFLKRAAQCKDYEGFEAGVVV
                     VDSEGVMHERKGAIMLPEDTLIGGWARVHRKNFKVPVEIVVSREEYDKKQSTWNTMPA
                     TMIRKVALVNALREAFPEDLGNMYTEDDGGETFDRIKDVTPQESREDVVARKMAEIEQ
                     FNKEQEANHADPEPAQTEETIQGELLDGELEY"
     gene            2853..3842
                     /locus_tag="VXC24_001875"
     CDS             2853..3842
                     /locus_tag="VXC24_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0493948.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFQQ
                     IKADYEFEKEELRQAPKSTETPNFDPETGKILDGGQILQNEPNALRGAENDLKRYAQK
                     MTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQVSGYQRIEPLTQAELNEQCGW"
     gene            3845..4030
                     /locus_tag="VXC24_001876"
     CDS             3845..4030
                     /locus_tag="VXC24_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493949.1"
                     /translation="MTEIEKISEELAEYGVPDELIGKIEDLLATLYGEKRKLEIEKSW
                     IFLQSQWGGNHGHQKNI"
     gene            4008..4331
                     /locus_tag="VXC24_001877"
     CDS             4008..4331
                     /locus_tag="VXC24_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493950.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEKFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            4324..4659
                     /locus_tag="VXC24_001878"
     CDS             4324..4659
                     /locus_tag="VXC24_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV0493951.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            4754..5170
                     /gene="ssb"
                     /locus_tag="VXC24_001879"
     CDS             4754..5170
                     /gene="ssb"
                     /locus_tag="VXC24_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0493952.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGLTGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            5180..5686
                     /locus_tag="VXC24_001880"
     CDS             5180..5686
                     /locus_tag="VXC24_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0493953.1"
                     /translation="MSKIKILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMPFEDNTFNLVVFDPPHLKWAGPNSIMKAQYGQLDKVTWSEDLAKGFE
                     ECLRVLKVGGTLVFKWSDRQINVKKLLEVIPFKPLFGQQRGTTHWLTFVKFEEDKNGV
                     DGLGGLET"
     gene            5652..5861
                     /locus_tag="VXC24_001881"
     CDS             5652..5861
                     /locus_tag="VXC24_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493954.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            5875..6204
                     /locus_tag="VXC24_001882"
     CDS             5875..6204
                     /locus_tag="VXC24_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493955.1"
                     /translation="MASKINATERIAIIIEKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            6201..6632
                     /locus_tag="VXC24_001883"
     CDS             6201..6632
                     /locus_tag="VXC24_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV0493956.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            6648..6830
                     /locus_tag="VXC24_001884"
     CDS             6648..6830
                     /locus_tag="VXC24_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493957.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            6855..7181
                     /locus_tag="VXC24_001885"
     CDS             6855..7181
                     /locus_tag="VXC24_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493958.1"
                     /translation="MMEELKQKVNAVYNWTVEDGKPQPPQQDLPQVVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGSEDE"
     gene            7174..7659
                     /locus_tag="VXC24_001886"
     CDS             7174..7659
                     /locus_tag="VXC24_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0493959.1"
                     /translation="MNKQELIDYCNVLKESKSRFINCIDVDRIIDTIKQLDEPEKVKV
                     PRFVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVARAWLDGYEVEEEK
                     RYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCEGIEIEGV
                     E"
     gene            7659..7847
                     /locus_tag="VXC24_001887"
     CDS             7659..7847
                     /locus_tag="VXC24_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HEV0493960.1"
                     /translation="MSCSENLKKEKELTAAISNFKIEVLQNDDKLSSLSLSNIKRQAR
                     DLYECLVWLQYNAEESGR"
     gene            7844..8182
                     /locus_tag="VXC24_001888"
     CDS             7844..8182
                     /locus_tag="VXC24_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493961.1"
                     /translation="MSYDLEILVKIESGDYICIAEPKYSSPTYNLGRMFRVAMNWDFD
                     QDTTYNIADVLDNIQRGISELERYPEKYVQYEPENRWGTVSVALEVLKSLKECILEQD
                     IDTKYLYMRW"
     gene            8184..8444
                     /locus_tag="VXC24_001889"
     CDS             8184..8444
                     /locus_tag="VXC24_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV0493962.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            8441..8863
                     /locus_tag="VXC24_001890"
     CDS             8441..8863
                     /locus_tag="VXC24_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493963.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGELEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
BASE COUNT         3126 a         1471 c         2056 g         2266 t
ORIGIN      
        1 tacttcatca gcgaatctac aacgtacaga gaagctaaaa tagcgtgtga gaagctattg
       61 aaacaagtca gccatgagat agaactcagg gcaatggaaa gtaagacagt ctagaagaca
      121 acaaaaagca cctgacggca atcaggcgca tactaaaaaa ctttacaaga ggattataac
      181 atgaatatga acttaaatac aaatgaaatt ttaacaacta ctgaatatga tatgtttcgc
      241 aaaattagta atagaaaaat aactgaaaat cctaaattgg aagaggagct actttctgag
      301 ggacaacgtc agccgatttt ggtaaatgaa aaaatggaag ttatcgacgg gcaacatcgt
      361 ctttattact tgagaaaaca tagaaaacca gtgcgctaca taattgatcc gaccgctaat
      421 ttcaagacag taatttcgat gaatacatca gctgtcaact gggcattaca agattatgtg
      481 tattcgttcg ctttagaggg agatcctgaa tttgttaaat tagctaaatt tttagacgag
      541 aacgaattgc ttagtgacaa gatggtaatc gtagctggtt caggaagacg tgatggtacg
      601 gcagcacacg tagtcaaaaa attaaaaaaa ggcgattatg tattttcaaa cgaaaaacag
      661 ttaagagaat tttgtaagtt ctacgaacgc gttttaaacg aaacaaaact gcctaacaaa
      721 ccatttttac aatctgtttt atggactttg tatacaacat cagtttttga tgaaaacaga
      781 atgttgacac aattgaagaa atcagatttg acatcagaag atatcgaagg atttgcaaag
      841 aaaaaattgc tattaacttt tttagagcta tacaacggaa gatggagtga cgatcatcct
      901 tctttaattc aatactttat caacagaaaa gggtcgttaa caattcctag tttgcctaaa
      961 caagatgaag ataattaaaa aagtaggaag ataaaatgaa agtcacagta tatgtttacg
     1021 gccgaaaatt agaaccagat gaaccaatta tcatcccaga aaatcatcgt ttttatgaca
     1081 tttggaacgg aattgtaaat gaaatgctcg acaacgagga ggatgtagct taatgaaact
     1141 acttactaaa ttaaaactca gactcgaagg agttcttaaa tcagtcaacc ttgactggag
     1201 agaggtagca gtcgaactta tgaacgacct atttgaggag cgcaagcgtc gctttgcttt
     1261 cgagcaagaa aactatgact tgaagcaaca attggcaatc tacaaagaaa aagaacaagg
     1321 agaacaatat gtttaaagca ctaaaaacaa tcaaaaaaat caaacagctt cagaaagaaa
     1381 tgcacgacgc aagcgtagca ttcctactta tgcaagacct cggtttggtt cctgatagcg
     1441 aaaaaggaag aaccatagct aaatcgtttt atgatgtaag ccacatgctc aaggacgtcc
     1501 tgggcggcaa gtcggtagat gaagccatga aacgtctaaa tagcgaagtg aaaattgaag
     1561 atgtggagca ggaagatgac tagaattgaa cttgaaaacc gtgtatggct tttggctaat
     1621 catgaagaaa aaaacgaatt gctggatctt gggctaacat ccaaggctag atatgtgaag
     1681 cgagttctgg aactaggaaa ggtgtatgct catgtttgat tacgacagag acataatgca
     1741 accgcctgaa gaacgagaag aacgtgaccc agctgattgg attttcagcg ctggtcaatg
     1801 gatctatgta ggagattgtt agcctatgaa tagagagcat ttagagcgtg aaaattggaa
     1861 tttgaagaag acgaaaggta gaaagaaatg aaaaaacgat tatattacaa aaaatggaaa
     1921 caagaactta gagaggcaat gagagaagaa attgatggcg attatctaac cgagaaaatg
     1981 gttagaaaaa tgagtattag cgatatgtca cactatttga accaattagc attagaagaa
     2041 gctggatact gtgggacaat gtttaattac taaaagaaaa aggagagaaa atgactaata
     2101 atcaattagc aacacagaca aaacgtaaca tcactactga cccaagttta ttgaccgggg
     2161 cagacatcaa aaagtatttt gacccacaaa acctactgac tgaaaaacaa gtaggtcagg
     2221 cgctagcctt gtgtaaaggt cgcaatctta acccatttgc taacgaggtc tacattgtag
     2281 cttacacaaa ccgtaatggg ggtaaagagt ttagcttgat tgtctctaaa gaggctttct
     2341 tgaaacgtgc cgcccaatgt aaagactatg aaggctttga ggctggagta gtggtagtag
     2401 acagtgaggg tgttatgcac gaacgcaaag gggcaatcat gctcccagaa gatacactga
     2461 taggcggatg ggctagagtg caccgcaaaa atttcaaggt acctgtggaa attgttgtca
     2521 gtcgtgagga atatgacaag aaacaaagta catggaacac catgccagct accatgatca
     2581 ggaaagtggc tctagtaaat gctcttagag aggctttccc tgaggacttg gggaacatgt
     2641 acacagagga cgacggtgga gagacatttg accgtatcaa agacgtcaca cctcaagaga
     2701 gccgtgagga tgtcgtagca cgcaagatgg ctgaaattga gcaattcaac aaagagcaag
     2761 aggcaaatca tgcagatccc gaacctgctc aaactgagga aacaatccag ggcgaattgc
     2821 tagacggtga acttgaatat taggaggaca acatgcaaga attacaggtt attgatgata
     2881 agaaaatcaa taaaatctat gagatgatca caacggatga acttactaga gagtcttttg
     2941 aaaaagacct catagaggct actgagaagt acaaggacta tattcctaca gctggaactc
     3001 tcaaagacga caaggcaaag cgggctgaat ttaacaagtt aattgagtct aaaaatcgta
     3061 tccgtattga cactaaaaac ttactatcag agacagctaa cacatgggat agttatgcta
     3121 agtcaattat tgacccattt gcaaccgtag ttagtgaatt tgacaaaggt atcaaggaaa
     3181 tcgaagaaca tcaaagacaa ctaaaaatag atacggttaa gagttaccta gccaacaaat
     3241 cggctgagta catgctggat cctcgtctct ttgatgaaaa ggcccttgag tatgtcaaag
     3301 ctagcgattt tatggcagat ggcgtgacgc ttaaaaaagc cactatgaag tcacttgatg
     3361 acatggtcac atttgaattt cagaaacaac aagaatttga aaaagccaag tcagctattt
     3421 cagggttatg tgctgagtac ggcatgactg actcacctta cattagacag ctgaaagact
     3481 tgactcttgc tgaagtcttt caacaaatca aagctgatta tgagtttgaa aaggaagaac
     3541 tcagacaggc tccaaaatca acggaaaccc caaattttga cccagaaacg ggcaaaatct
     3601 tggacggtgg acaaatcctc caaaatgagc ctaacgctct tagaggggct gaaaatgacc
     3661 taaaacgata tgcccaaaaa atgactttag aggtgtattt tgtagacaca gccgaaaaag
     3721 accgtttcaa ggctggtcta agtcaactcg gatttgattt taaaaagaac tatcaagtca
     3781 gcggttatca acgtatcgag ccattaactc aggctgaact aaatgaacaa tgtgggtggt
     3841 aagtatgaca gaaattgaaa aaatttcaga agaattggct gaatatgggg tgcctgatga
     3901 gttaatagga aaaatagagg acctattagc gactctgtat ggcgaaaaaa ggaaattgga
     3961 gatagaaaaa tcttggatat ttctccagag tcaatgggga ggtaaccatg gacatcagaa
     4021 aaatatctga cagcgtagcc atctactcgg acggcaagaa attgcaggtt atccacaacc
     4081 taggggatga gtttatccta gattttaagg tgggagagga tagcgtctgg aacctcaatg
     4141 gccaagtcgt agaaattatt gacatgattg agcctgtctt taaagttttc agcttttgct
     4201 caaaatctgg agagggtatg caacgcttaa aacatgctat cgtccacttt gaaaaatttg
     4261 agcagtacat cagagataat caggaagacc tgatgatctg gtggcacaat ccaggagggg
     4321 aatatgatta aaaccgtatt tttttcatgt gattatccac atcatgaggt gattgacgac
     4381 caaataaata gctggcttgc cgaaaatcca ggcattaagt tgattgacat caaatttcaa
     4441 tcaaatgtgt ctgctgtcgc tgacagtgga gtcagtgctg aatattggca tacatccgca
     4501 ttgattattt acaaagttcc ctcagagaac aatataagca gtattaattc aaatggttta
     4561 ggtttcataa tcagctgtga gaaatgtggt agcttatcaa taatcaaggg aaaagatgta
     4621 ggtcaaaatg tatgttatga atgcaaagga gagaaataat gaatgatttt atcaaagaga
     4681 ttgggatggc tatcctatgg atgtttttag ggtatctctt gggagagcgt agcactagag
     4741 ggggacaaat cagatgatca ataacgtcac actggttggg aggcttgtag cgcctcctga
     4801 tctacgaaaa acgcctaata atgtatctag tttacagggc acgcttgcag tcaatcgcaa
     4861 tttcaaaaac gaaaatggag agcgtgaggc tgattttatc aattttcaag cttggagagg
     4921 tacagctgac atcattgctc agtattgcag caagggctca cttattggcc tcacagggcg
     4981 cttacaagtt aggtcttacg agaaagacgg tcagcgtcga tatgtgactg aagtaatcgc
     5041 tgagagtgta gctctgctag agagtcgcaa cagtcagcac ggacaaggca acagtttcca
     5101 aaatgggaat agctcacctt ttaccgatcc taaccccttt gacctcccaa atgacggttt
     5161 gccgttttag gaggtatata tgtcaaaaat taaaattctt gacgcttgct gtggcagtcg
     5221 tatgttttgg tttgataaaa acgaaagtca cacaattttt atggacatta ggcaagaaac
     5281 atttgagata catgacaaaa aggtcaatgt agaccctgat attatcggtg attttcgtga
     5341 catgcctttt gaagacaaca catttaatct agttgtgttt gatccaccac atctaaaatg
     5401 ggctggacct aattcgataa tgaaagctca gtatggacag ctggacaaag ttacctggtc
     5461 ggaagatttg gccaagggtt ttgaagaatg tctgagagtt ctaaaagttg gcggcacact
     5521 agtctttaaa tggtctgacc gtcagataaa tgtaaagaaa ttactagagg tgataccatt
     5581 caagccctta tttggtcagc aaagaggcac cacacactgg ctaacgtttg taaagtttga
     5641 ggaggacaag aatggagtgg acggattggg tggattggaa acctgaaacc aaaacggaca
     5701 ttaaaaccaa aattgaaaat gacgggtaca cttttccaca ctatgacaag aaaaacaacg
     5761 gcgtcaagta cgtcatctct acactggaca tcaaacgaga ctgtctaaga cttggagtac
     5821 cgtttgaaga tgtgtaccct ttgcaaacga cactttttta acaggagaaa gaacatggca
     5881 agtaaaatca atgcgacaga acgtattgct atcatcattg agaaacaaaa aatagaggtc
     5941 gttacgactc taaactatga tatgagcatt agctttgata acaaagacac ggctcctaca
     6001 ctagatgaca atggtgacct ttttgaaccg gtctacaagt gcaaagttaa ggcaattccc
     6061 aaaaatgatg tatttttcac ctcattaaca cgagtcaaga gcaacatcaa gacgctacaa
     6121 gaggttaaaa aattctttga gttcgtaaac gaaaacagag aaaatctctt tgagatggca
     6181 ggatttaagg gggctcttga atgaaattga ccctaaacat tgagcctaaa cctcaatcac
     6241 ggccaaggtt tgcaagacgt gggagtttta ccacaactta cgaagacaag gatatgaaaa
     6301 catggcgcaa tcattgccag ctgctcattg ctaatcagta catgggtcag cctatccttg
     6361 agggagcttt gagggcacgg cttagatttt atatcaaacc tcctcagtac atttccaagg
     6421 tcaagaagaa ccagcaggcc ctcctagatg aaatcatccc agtaggcaaa aagcctgaca
     6481 ttgacaacta cgaaaaagcc ctatatgaca gtatgtcagg gatcgtattc caagacgacg
     6541 gtcagatagc tctgcatgat gtaggcaagt tctacagtct aaatccacgg atagaggttg
     6601 agattgaggt catgaaatcc ctgagtattt gaagaaatga ggagcagatg gctgactacg
     6661 cattatatca aggtgatgtg tttgttacgc ttggaacatt agcgcagatc agtagcgaga
     6721 caggaattac tgaaaggatg ttaaagtatt acacttacac atcacaccaa agacgacacc
     6781 caaacggtag ggccgttatt aaaattgagg aggaagataa tgagaattaa gacggaaagc
     6841 ggaggagttg gaagatgatg gaagagttaa agcaaaaagt taatgcagta tacaactgga
     6901 cggtagaaga cgggaagccg caacctcccc agcaagattt accacaagtg gtgaaagacc
     6961 gggcggacta tttttgggaa atggcagaag atggtatgac gtttatggga gcgatggaat
     7021 gcatctttgc tgatgaaaag cctacagact atgatttggg agctactaag gattggttgc
     7081 caaaatctaa ggagtttgat gattgggttg gctattcgcc aagcatggct caggtagtta
     7141 ttgcagttta tttgatttat ggaggaagcg aagatgaata agcaggaatt gattgattat
     7201 tgtaacgttt taaaagaaag taaaagtaga tttatcaatt gtattgatgt agacagaatc
     7261 atagatacaa tcaaacaact agacgaacca gaaaaagtca aagttccgcg gtttgtggct
     7321 gaatggattg aggaagctag aaaagcttgt aaagacgtgg tagaattatt cgaatttgat
     7381 ttcacgaacg atgaagttag aaaatggttt atgcaagaaa gaccatttga tttagtagct
     7441 agagcatggc ttgatggcta cgaggtcgag gaagagaagc ggtatttggt gactttaaaa
     7501 aataggcagc ctttggtcaa atcgcaatca gggagtactc tttattttag tcaagatata
     7561 acagctagga attataaagg tactcaaaaa gaactagaag acgcaaactt cggctgggtg
     7621 tttgattgtg aaggaattga gattgagggg gtggagtgat gtcatgtagt gaaaatttaa
     7681 aaaaagaaaa agaattgact gctgctattt caaatttcaa gatagaagtc ttacaaaatg
     7741 atgataaatt gagcagtcta tcattaagca acatcaaaag gcaagcaagg gatctatatg
     7801 aatgcttagt atggttgcag tataatgcgg aggaatcagg tagatgagtt atgatttgga
     7861 aatattagta aaaatagaga gtggagatta tatttgtatc gctgaaccta aatatagttc
     7921 tccgacctac aatcttggaa gaatgtttag agttgctatg aactgggatt ttgatcaaga
     7981 cactacgtac aacatcgctg atgttttaga taacattcaa cgcggtatct ctgaactaga
     8041 acggtaccct gaaaagtatg tgcagtatga acctgaaaat agatggggaa cagttagcgt
     8101 tgcattggag gttttaaagt cactgaaaga gtgtatttta gaacaagata ttgatacgaa
     8161 atatttatat atgaggtggt aatatgaaac gattcatagc tatctggatt ctgctatctg
     8221 ctggattgaa tatctggcag agtatctaca ttaaaaagtt agaagaaaag cgtccgattg
     8281 tcgtctataa agctgataac gcaggcgctg agatattcgg taaagtcgtc gagaaaggac
     8341 ggcatggcaa gctatatacg cttaccattc gtgactacgg ggtgttcgtg gttacgaagg
     8401 acgtgtacga taaagtgaaa gttggggatg aggtgttact atgacagaaa ctattaaact
     8461 accagactat tatgagcctg attggaaaaa tgcaaggtac gggtcgttgg aagagcttaa
     8521 agaattgttg ctctttaagc gtattgtgaa atgggataag gactttttgc tgcttgaaga
     8581 cggcacaaag gtcactattg aaatgtctga aagtgattgc tgtgcctcag caggtgggga
     8641 gttccaagat gtatcacttg acgctgtgat tactaatatt gaaattggag aactggaaga
     8701 aatccccgac cattggggaa ctggttataa aaacaaagta actatcttcc ataatcagaa
     8761 ccctgtagct attgccaatt gtgaagcaga gcataacggc tattattaca gcgtatgctc
     8821 tttagtgatt ggtgatattc attttccagt tgttaatgct taggaggatt taacatgaca
     8881 ccaagatata gagcgtggat aaaaacagaa aaacgtatg
//
LOCUS       DAVLBN010000074         8836 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLBN010000074 DAVLBN010000000
VERSION     DAVLBN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8836
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.074"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..406
                     /locus_tag="VXC24_001891"
     CDS             <1..406
                     /locus_tag="VXC24_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV0493964.1"
                     /translation="SVIKISTDIERIGDRIVEILKNLQILQNNEILKKIISEIKILHE
                     VIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVSEVI
                     SALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            419..1894
                     /gene="galT"
                     /locus_tag="VXC24_001892"
     CDS             419..1894
                     /gene="galT"
                     /locus_tag="VXC24_001892"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0493965.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1907..2917
                     /gene="galE"
                     /locus_tag="VXC24_001893"
     CDS             1907..2917
                     /gene="galE"
                     /locus_tag="VXC24_001893"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0493966.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3081..3740
                     /locus_tag="VXC24_001894"
     CDS             3081..3740
                     /locus_tag="VXC24_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0493967.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3765..4832
                     /locus_tag="VXC24_001895"
     CDS             3765..4832
                     /locus_tag="VXC24_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0493968.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4936..5946
                     /locus_tag="VXC24_001896"
     CDS             4936..5946
                     /locus_tag="VXC24_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0493969.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5958..7649
                     /locus_tag="VXC24_001897"
     CDS             5958..7649
                     /locus_tag="VXC24_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0493970.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7652..8362
                     /locus_tag="VXC24_001898"
     CDS             7652..8362
                     /locus_tag="VXC24_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0493971.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            8458..8826
                     /locus_tag="VXC24_001899"
     CDS             8458..8826
                     /locus_tag="VXC24_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493972.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
BASE COUNT         3016 a         1193 c         1718 g         2909 t
ORIGIN      
        1 tagtgtaata aaaatatcaa ctgacattga acgtattggg gatagaattg ttgaaatttt
       61 aaaaaatcta cagattcttc aaaataatga aattttgaag aaaattattt cagaaataaa
      121 aatacttcat gaagttatcg gactgcatat gaatagggct atatcttgtt atagagagga
      181 acaatctgga tgtttagata tggttgttat acaaaaacag aatgagatag aagagcttag
      241 tataaatatg gaaaagaaaa taatgaatta catatttgaa gatgatggga acgtttctga
      301 agtaattagt gctttagata ttattcatca ccttgataaa attgctcata ctacgcaagc
      361 aatttataaa tggataatgt atagaaaata tgggaacata aattagaaag aaaaatatat
      421 gaaaacaatt attgataatt ttgttgatag agtaattgaa tacggaatgt ataatgaaat
      481 tgacaaaata tatgtgaaaa atagagtact agcgttaata ggtgaggagg gaattgatcg
      541 catttccgat gaaaatgacc tgaaacaaat aaaagattac ttagtggaaa tcgccttaaa
      601 aaacggtaaa attaaagatt taatcgagga aaaggaatgt ttaggagcag agttaatgaa
      661 tttcatagtt cctttaccta gtcgattaaa tgatattttt tggagttcat atgatatatc
      721 acctcaagaa gcagttgaag agttttataa gttaagtaaa gatagtgatt atattaaaac
      781 ttctgctatt gctaagaata ttgagtttcg agcatcaact aaatacggag agctagagat
      841 tacgataaat ttgtcaaaac ccgaaaaaga tccaaaaaca attgctgctg aaaaattagt
      901 aaaagcaact aattatccca aatgtttact atgtatggaa aatgaaggat atcaggggcg
      961 aataaattat ccagcacgtt cgaatcatag aattattcgg ttgaaacttg gtgacgaagt
     1021 atggggattc cagtattctc cctactcata ctttaatgag catgcgatat ttttgaatag
     1081 tcaacatgta ccaatggcta ttacctctaa aacatttgaa caattattgg agattgttga
     1141 tattttgcca ggatattttg ctggttcaaa ttctgatctt cctatctcag gaggctccat
     1201 tcttagtcat aaccactacc agggagggaa acatattttc ccaatggaaa aagcaaaatt
     1261 tgagagtgaa ttttgtttta aagactttga ggatgttaat gctggtattg taaaatggcc
     1321 aatgtcagta attaggttac aaagtgaaaa taaaaatcgc ttgttagatt tagctactaa
     1381 aattctaaat aagtggagag aatattcaga tttagaagta gacatcattg ctatgactga
     1441 agatgtccca caccatacgg tgactcctat tgctcgtaaa gtggacggga gatacgaatt
     1501 agatattgtt ctaagagata atcatactac tgaacaatac ccagatggtg ttttccatcc
     1561 tcatcaagat gtacaacata ttaaaaagga aaatatcggg ttaatcgaag tgatgggact
     1621 tgcgatatta ccacctcgtt tgaaaccaga gttagaagaa gttggaaaat atcttttagg
     1681 agaggataat gcaattgcgg attatcattt agaatgggcc gaccaattga aagaaaaata
     1741 tcctcgcatt aataaagaag aggttaatag cgtagttcaa cacgaagcag gacaagtgtt
     1801 tgcgagagtt ctggaagatg caggagttta taagaataca ccgtctgggc atgaagcgtt
     1861 tatgagattt gttaagtcgg ttggaattaa ttaggaggaa acccagatgg caatattggt
     1921 aacaggcgga gctggttata ttggtagcca taccgtagta gaattactaa atttaggaaa
     1981 ggaagttatc attgtcgaca acctttcgaa ctctagcaaa ttggtgctag accgtattga
     2041 agcaattaca ggaatacgtc ccgtgtttta cgaattagat gtttgtgata aacaagcatt
     2101 gagaaaggta tttgaacaag aatcgattga tgctgcaatt cattttgcag gttataaagc
     2161 tgtcggagaa tccgtgcaaa agcctgtgat gtactacaaa aataatatta tgagtacatt
     2221 ggcacttgtt gaagtgatgt cagaatttaa tgttaaaaag attgtctttt cttcaagtgc
     2281 gactgtatat ggaattaaca atcagtcacc tctaattgag acgatgcaaa caagtgcgac
     2341 aaatccttat gggtatacga aagtgatgct tgagcaaatt ttaaaagatg ttcatgtggc
     2401 agattcagaa tggagtattg cgttgcttcg ttatttcaat ccaattggtg ctcatgagtc
     2461 tggtttgatt ggggaagatc cctcaggaat tcctaacaac ttgatgcctt atattgcaca
     2521 agtagcggta ggtaagctat cagagctaag tgtgttcgga aatgattatg atacgcttga
     2581 tggtactggt gtgcgtgatt atatccatgt agtagattta gcaataggac atataaaagc
     2641 tttagaaaaa gtatctgaaa aaacagatgt ttatatctat aacctaggct cgggagaagg
     2701 cactagtgta ttacaacttg taaatatatt tgaaagtgtt aataagatcc ctattcctta
     2761 taaaatagtt ccaagacgtt caggagacgt tgcaacttat tatgcaaatg cagacaaagc
     2821 atataaggaa ttaaattgga ggacaacaaa atcgattgaa gacatgtgta gagatacatg
     2881 gaattggcaa tcaaaaaatc ccaatggcta taattgatga tactgtctat atgagtgctg
     2941 tattttggaa aaattactta accttttaat gaaagataaa ttaaaaaaaa tgtttgacag
     3001 cgcttgacaa aggaaacggt ttcattgtat aatgtaaaca caatgacacc gatgtcaaat
     3061 ataaaaaaga aggtctttat atgaaaaact taacaaaaat taagttcaaa gaaaatgggg
     3121 aatttaatca tttccctggg aatacagttg tagcaaatct ttatactaaa caagatttga
     3181 tggaagttgt tgatattatt caatcacgtt atagagaatt accatttatc gataagttta
     3241 ctttaactcc aaggaattct attcacatga ctgtaattga attgttgtgc catgaaaatc
     3301 gtgaaacgga gttttggagc agtaatcttc ctctagatac acctttacag gaaatacatg
     3361 attactttgc taaacaactt gaaatttttc cattgttgga tgaagaaatt catatgcgta
     3421 taactgaaat gggaaaacaa aacatactag ttgaacctgc agatgaagct tctgcaaaga
     3481 gattagaaga aattcgtact tatgtctcag aaaaagcagg tgtttgtttc cctaatcatg
     3541 atagatatca attccatatt tcaattgggt atcttcggat tcctctaacc gaagaggagg
     3601 aagaagagtt tactaaagtc agagcagaat taactgaaat tttattagag aagattccaa
     3661 ctattactgt aaaccgtatt gactatactg tatttgaaga tatgagacaa tttgttccat
     3721 atcacgaaaa atttaaataa aataataaaa aaggagaact tatcatgaaa aaaatgaaag
     3781 tttggtctac tgtacttgca acgggagttg ctcttactac acttgctgct tgctctggag
     3841 gttcaaattc tacgactgct tcttcatctg aagaaaaagc tgataaaagt caagaattag
     3901 ttatctattc gaactcagtc tcaaatggtc gtggtgattg gttaactgct aaagcaaaag
     3961 aagctggttt taatataaaa atggttgata tcgctggcgc tcaattagca gaccgtgtta
     4021 ttgctgagaa gaataatgca gttgcagata tggtatttgg aattggtgct gttgactcaa
     4081 ataaaattag agatcaaaaa ttactagtac agtacaagcc taaatggtta gataaaattg
     4141 atcaatcttt atcagataaa gataattatt ataatcctgt gattgttcaa ccattagttt
     4201 taattggggc gcctgatgta aaagaaatgc ctaaagattg gactgaatta ggtagtaagt
     4261 ataaaggtaa atattcaatt tatggtcttc aaggtggtac aggacgggca attctagcaa
     4321 gtatcttagt tcgttacctg gatgaaaaag gagatttagg cgtatcagaa aaaggatggg
     4381 aagttgcaaa agaatacttt gcaaatgcct atactcttca aaaaggtgaa agctcagttg
     4441 ttaaagcgtt agataaagaa agcccaattc aatacggtat gatctggggt tctggagcgt
     4501 taatcggaca aaaagaacaa aatgttgaat tcaaagttat gactcctgag attggtgtac
     4561 catttgtaac tgaacaaact atggttttaa gcactagtaa aaaacaagcg ttagctaaag
     4621 aatttattga ttggtttggt caatcagaaa ttcaagtaga atatagtaaa aaatttggat
     4681 ctattcctgc aaataaagat gccctaaaag agttacctga agatacgaaa aaatttgttg
     4741 atcaagtgaa accacaaaat attgactggg aagctgttgg aaagcatttg gatgaatggg
     4801 tagaaaaagc tgaattagaa tacgtaaaat aagaaataag agttattttt tatgtccaag
     4861 tctctctatt atttctaaat ttaaggaaga aataaagaga ggcttttggt tttagtaata
     4921 gagggagtta gtgagatgat taaatttgat aatattcaaa ttaaatatgg tgattttgtt
     4981 gcaattgata atctgaattt agatatacat gaaggggaat tctttacatt tcttgggcct
     5041 tcaggatgtg gtaaatcaac tactttgaga gcattggtag gttttttaga tccatcatca
     5101 ggaagtattg aagttaatgg aacagatgtc actcatttgg aacctgaaaa gcgtgggatt
     5161 ggtattgtat ttcaatctta tgcgctattt ccaactatga ctgtttttga taatattgca
     5221 tttggtttaa aagttaagaa ggtagctcca gatgttatta aagctaaagt atcagcagtg
     5281 gcagcaaaaa ttaagatctc tgatcaacag ttacagcgta atgtatcaga attatctggg
     5341 ggtcaacaac aaagggtagc attggctcgt gctctggttc ttgaacctaa aattctttgt
     5401 ctagatgaac cattgtcaaa ccttgacgca aaattacgtg tagatttgag aaaagagttg
     5461 aaaagacttc aaaaagagtt aggtattact actttatatg ttactcatga tcaagaggaa
     5521 gccttgactt tatctgatag aattgcagtc tttaacaatg gatacatcga acaggtcggt
     5581 acaccagtag agatttatca taattctcaa actgaatttg tatgtgattt tattggagat
     5641 attaatgttt tgaccgatga aacagtccac gaagtattat tgaaaaatac aagcgttttc
     5701 ttagaggata aaaaaggata cattcgatta gagaaagttc gattcaatcg tgaaactgaa
     5761 caagatttta ttctaaaagg gacaattatt gatgttgagt tttctggagt tacaattcac
     5821 tatacaataa aagtttctga aagtcagatt cttaatgtaa caagtattga tagtcaggct
     5881 gctattagat ctgtcggaga aagtgtggaa ttatttatca caccatcaga cgttctgcaa
     5941 ttttaaggag gtgcagtatg cgtcataaat taaatttaaa agattggctt attcgtttag
     6001 ggttaatctg gttcttagta acatttatta tttatccaaa ctttgatcta gtagtgaatg
     6061 tatttgtaaa aggaggagaa ttttcccttg atgctgtaca tcgtgttcta aaatctcaga
     6121 gggcacttca gagtattatg aacagtttta agttagcatt ttcactcatt attacagtta
     6181 atgtcgtagg tattctttgt gttctattta cagagtactt tgatattaaa ggtgctaaaa
     6241 ttttaaaatt aggttatatg acctctttaa tttatggagg agtggtttta gcgactggat
     6301 ataaatttgt ctatggtcct tatggattga ttacaaaatt tttacaaaat gttatccctt
     6361 ctttagactc taactggttt attgggtatg gtgcagtctt attcattatg acattttcag
     6421 gaactgctaa tcatacattg tttttaacaa atacaattcg aagcgttgac tatcacacta
     6481 ttgaggctgc tcgaaatatg ggagcaaaac catttactgt tttccgaaaa gtagtgttac
     6541 caaccttaat tccaactcta tttgcactta ctattatggt ttttcttagt ggtttatctg
     6601 cagtagcagc acccatgatt gttggtggta aagaatttca aactataaat ccaatgatta
     6661 ttacatttgc agggatgggg aattctcgtg atttagctgc cttacttgca attattttag
     6721 gtattgcaac tacaattttg cttactatca tgaataagat agaaaaaggt ggaaattata
     6781 tttctatctc taagactaaa gcgcctctta aaaaacaaaa aattgcgtct aagccttgga
     6841 atatcattgc tcacattgta gcatatggat tgttcacagt tttcatgctt ccactaattt
     6901 ttatagtatt atactcattt acagatccag ttgcaattca aacaggtaac ttaacattat
     6961 caaactttac tttagaaaat tatcgcttat tctttagtaa tagtgcggca ttctctccat
     7021 tcttggtcag ctttatttat tctattattg ctgcgacaac agcaacaatt ctcgcagttg
     7081 tatttgctcg tgttgtcaga aaacataaat ctcgttttga tttcttattt gaatatggtg
     7141 ctctacttcc ttggttacta ccaagtacac ttttagcagt aagtttatta tttactttta
     7201 atcagccaca atttcttgtt ttgaatcaga ttttggtagg tagtttggta attctactta
     7261 ttgcatatat agttgtaaaa atcccatttt cttatagaat ggtacgtgct attttattta
     7321 gtgttgatga tgagatggaa gatgcagcaa gaagtatggg tgcttcacct ttttatacta
     7381 tgatgaaggt tatcattcca tttattttac cggttgttct ctctgttatt gctttaaact
     7441 ttaactcttt attaactgac ttcgacttat ctgtattcct ttaccatccc ctagctcaac
     7501 cattaggtat tacgattcga tctgcaggtg atgaaacagc aacatctaat gcacaagctc
     7561 tggtatttgt ttatacaatt gttctgatga ttatttctgg aacggtatta tacttcacac
     7621 aaagaccggg gcgtaaagta aggaaataat catgacagcc actagtcttg ggttatcaaa
     7681 tattgaaata gttgtcagga ttgttttatc agtagtcatt ggtagtataa ttggtttaga
     7741 gagagggagc aaatcccagc ctgcaggcat ccgaacttat agtattgttt gtctagctgc
     7801 atgtttgatt atgatgacga atgaatacgt atcttataaa tttgggacag gagatcctac
     7861 acgattagga gctcaagtta tatcaggtgt gggttttcta ggcgctggaa cgattcttat
     7921 tacagataag aagaaaatta caggtctgac aactgcagca ggcatttggg cttcggcagg
     7981 aattggatta gctattggag taggttttta tgagggagct cttttagtag ccatttctgt
     8041 ttggggtgtg atatccatgt tccaaccact aaaaaaatat ctgcaaaatc gttctaaaat
     8101 gattgaattg tatatagtag ttaaatctac agaagcctat aatcgtgtat tggtttattg
     8161 tgcagaaaat ggtatcagaa tgaccgattc aagaacagcg tttggagatg ttaattctga
     8221 cagaattgaa tactttgatg ttccggacaa aaaaatagcg tcatttatta ctctggaatt
     8281 atcaggtaga tttgaacatc ttcgactgat ggaagaaatt gctaatattg taggtgttat
     8341 ttatgtcgaa gaaattagct gaaatttagt aaacaaaggg acagatgttt ttgtcctttt
     8401 gttttttaga tgttttaatc atctaatttt tgagtagatt tttgctcaga ggtttttatg
     8461 aaagattata aaatcaattt tgatttaggt aaaatagaat attttgataa taattgtttg
     8521 atacaagtat acaaatttat ttctttttat gatatttgtg aaatggtgtt tgcctttcat
     8581 ttacctcctg atgagttgat aacaaatgtt atctttaaag aaaaaattaa ctctatgtta
     8641 aaatgttaca ttgacaggct attatatgtt tttataaatc ctacacattt tactgaaaaa
     8701 gttaatctac aattttatgg cagttttttc tcatatgaat ttatttgtcg tgaagttgga
     8761 aacattctta aaaataaagg tgtgaaatgc aatttaaact tttttgaagg ggaagaatat
     8821 ttgtaaaatt aatttt
//
LOCUS       DAVLBN010000075         8498 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLBN010000075 DAVLBN010000000
VERSION     DAVLBN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.075"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..186
                     /locus_tag="VXC24_001900"
     CDS             <1..186
                     /locus_tag="VXC24_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493973.1"
                     /translation="KHEEIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLIK
                     AIQELNQKIEKMEKTIA"
     gene            280..483
                     /locus_tag="VXC24_001901"
     CDS             280..483
                     /locus_tag="VXC24_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493974.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            486..836
                     /locus_tag="VXC24_001902"
     CDS             486..836
                     /locus_tag="VXC24_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493975.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            845..1261
                     /locus_tag="VXC24_001903"
     CDS             845..1261
                     /locus_tag="VXC24_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0493976.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLFRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            1265..1597
                     /locus_tag="VXC24_001904"
     CDS             1265..1597
                     /locus_tag="VXC24_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0493977.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKNLDTFVESAVKQ
                     MNDVWKGR"
     gene            1601..2557
                     /locus_tag="VXC24_001905"
     CDS             1601..2557
                     /locus_tag="VXC24_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0493978.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            2827..3069
                     /locus_tag="VXC24_001906"
     CDS             2827..3069
                     /locus_tag="VXC24_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493979.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            3096..3473
                     /locus_tag="VXC24_001907"
     CDS             3096..3473
                     /locus_tag="VXC24_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0493980.1"
                     /translation="MIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVN
                     MVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLLESRAQR
                     AMRENNAGQDLADLVLEEEELPF"
     gene            3743..4027
                     /gene="groES"
                     /locus_tag="VXC24_001908"
     CDS             3743..4027
                     /gene="groES"
                     /locus_tag="VXC24_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0493981.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            4043..5665
                     /gene="groL"
                     /locus_tag="VXC24_001909"
     CDS             4043..5665
                     /gene="groL"
                     /locus_tag="VXC24_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0493982.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            5803..6558
                     /locus_tag="VXC24_001910"
                     /pseudo
     CDS             5803..6558
                     /locus_tag="VXC24_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            7004..7777
                     /locus_tag="VXC24_001911"
     CDS             7004..7777
                     /locus_tag="VXC24_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0493983.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            7790..8128
                     /locus_tag="VXC24_001912"
     CDS             7790..8128
                     /locus_tag="VXC24_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0493984.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            8161..8498
                     /locus_tag="VXC24_001913"
                     /pseudo
     CDS             8161..8498
                     /locus_tag="VXC24_001913"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         2850 a         1446 c         1828 g         2374 t
ORIGIN      
        1 aaacatgagg agattggtct aatagctcaa gaggctgaaa ccatcgttcc aaaaattgtc
       61 tcacgagatc ctgagaatcc agatggctat ctgcatatcg actataccgc tttagttcct
      121 tacttaatca aggctattca agaattaaat caaaaaatag aaaaaatgga gaaaacaata
      181 gcatgaataa caacatgttg accaatatcg cacttaaagc aatttaggag cttgctcttg
      241 aaaatagaaa acgaacacac agattggaga acttagaaaa tgaacacaga acagcttaac
      301 caagccttac aaatgacaat tagtgaaatg tcaacaactt caacaaattc gatgattaca
      361 agtaatatct tgagtattca gttgaatgag caaagggaag agaatcaaag acttcaagca
      421 cgagtggatg agctggaagc tctgcttgat gaacaaacta aaccagcaga caaaggagaa
      481 tagacatggc agaaacaatt caaaacacag ataacttact agaccttaca aaaatcacag
      541 aaccatttga tcttgcgagc gctttgcgct acatgaaaga aaatggagag ttcattcgtt
      601 gcaagaatgt aagcgatgac ttctatatgt atcgtgacgt tcaaaaacgt cctgtgatcg
      661 taaatggccg tcgccaattc aaggatgttg aaaccgtttg ggcgttcaat cagtggggtg
      721 gtacaatcgc aacaatcaac gtagccgttc tgttgaatca tgaattctat atcatgaaat
      781 ttgatgcaga gggcaatcct gactggacgg ttccaacggt agaacctaaa gaataggagg
      841 ttgtatgcaa attgaatttt tcaattttct aagaagtgtc gtacagactg aagatggttt
      901 ggtattgtac gctctagcac tgattgtctc aatggaaatc attgattttg tgacagggac
      961 gattgcggca attatcaatc ctgacatcga gtacaagagc aaaatcggca tcaatgggct
     1021 atttcgtaag atttcagggg ttctcttact gatgatcctc attccggcgt ccgttttgtt
     1081 gcctgaaaag acaggttttg cattcttgta ctcaatctat ctcgggtaca tcgcatttac
     1141 ttttcaatct ctcattgaaa attaccgcaa attaaaagga aatgttactc tttttcagcc
     1201 gattgtaaaa gtatttcagc gattacttga aaaagatgat gatacgaaaa aaggagaata
     1261 acaaatgcaa caaattactg aaatcattac taatggagca atcagcatcc ttgttatttt
     1321 ggctggtatc gcagtcaagg cagtcaagga ctacctggtt caaaaaggtg gagaaaagac
     1381 catcaaaatc gttgaaatct tggccaaaaa tgcagtaaat gccgtggagc aggtagctgc
     1441 tgaaactggc tacaagggag atgaaaaact ggcacaggct cgtgctaaag tccgtgctga
     1501 gcttacaaaa tacaatatta gcatgactga caaaaactta gacaccttcg tagagtcagc
     1561 agtgaagcag atgaatgacg tatggaaagg acgataggga atggatatcg atagaaacag
     1621 actacgtaca ggcttgccac aggttggggt gcagccttat cgacaagtac acgcccactc
     1681 aacaggcaac cgtaactcaa cagctcaaaa tgaggctgat taccactata gaaaggaccc
     1741 tgaactaggg ttcttttcac atgttgtcgg aaatggccgt gtcatgcaag taggtcctgt
     1801 gaacaacgga agttgggatg ttgggggcgg ttggaatact gagagttacg cagcggttga
     1861 actgattgaa agccattcaa ctaaagaaga gttcatgacg gactaccgcc tttatatcga
     1921 actcttacgc aatctagcgg acgaagcagg cttgccgaag actcttgata cagacgactt
     1981 ggcaggtatc aagacgcatg aatactgtac caataaccaa ccaaacaacc actcagacca
     2041 tgtggatcca tatccatatc ttgcaagttg gggcattagc cgtgagcagt ttaagcaaga
     2101 catcgaaaac ggcttgagcg ctgcaacagg ctggcagaaa aatggcactg gctactggta
     2161 cgtacactca gacggctctt atccaaaaga caagtttgag aaaatcaacg gtacctggta
     2221 ttatttcgat ggctcaggct atatgctttc agaccgctgg aagaagcaca cagacggtaa
     2281 ttggtactac tttgaccaat caggcgaaat ggccacaggc tggaagaaaa tcgctgagaa
     2341 gtggtactat tttgatgtag aaggtgccat gaagacaggc tgggtcaagt acaaggacac
     2401 ttggtactac ttagacgcta aagaaggcgc catggtatca aatgccttta tccagtcagc
     2461 ggacggaaca ggttggtact acctcaaacc agacggaaca ctggcagata agccagactt
     2521 cacagtagag ccagatggct tgattacagt taaataaata gaaaggaaac tttctaaatt
     2581 gttctttcac cgcaggctca ggcttgcggt tttttatttg ctctgattct tcaaaaaagc
     2641 gtttacatga agaataggga ggaggaatgg cagggtatta ttgccaaaaa cgccattttg
     2701 ttaataatag ctccttttta ttttttgatt attgtcaaaa acggtgtttt gttaaaaata
     2761 aaaaaatagt gattttttca taacttttta tcttctttta cgaatagata agtaggagga
     2821 ataaaaatga agattttaaa tattgaacta gcaaatgtag agcagacaga tttaggtttt
     2881 gagcattggg tagatgtgac ttacaacgtc ccaattttga aaaacgaata cacggttaga
     2941 ttgttgctgc tctttggttt tgaaattgaa gatcctgaag tgattgaata cctggtcaac
     3001 gcttggaaat atcgtgagct ggtcttacat tctgtgagga tgtatgatat ggagagagaa
     3061 gcaagttaaa atactgttac taactctaac ttatcatgat tgggcgttta acgtctacac
     3121 cagaattgca caaaaccaac aatgacaagt cggtagcgcg agcaactatc gctgtcaacc
     3181 gtcgttacaa agaccaaaac ggtgaacgtg aagctgattt tgtcaatatg gtcctatggg
     3241 gcagactagc agaaactttg gcaagctacg caaccaaagg tagtctcatt tccgttgatg
     3301 gagaattgcg tacccgtcgc tttgagaaaa atggccaaat gaactacgtg accgaagtac
     3361 ttgtaacagg attccaactc ttggaaagtc gtgctcaacg tgccatgcgt gaaaataatg
     3421 caggccaaga tttggcagat ttagtcttgg aagaggaaga attgccattt taatactctt
     3481 cgaaaatctc ttcaaaccac gttagcttta tccacaacat caaagcaatg ctttgagcag
     3541 cctgcggcta gcttcctagt ttgatctttg attttcattg agtataaaca ttaaaaagtc
     3601 tgagttggtc tcaggctttt tatcttgaga aagtcagact tttttcttga ttatttctga
     3661 ctaagtgata caatagaact atgaattagc actcaggtat aaagagtgct aataatatct
     3721 atctcattat ggaggaaatc agatgttgaa accattaggg gaccgtgtgg tcttaaaagt
     3781 agaagaaaaa gaacaaactg ttggaggctt tgttctcgca ggttcagccc aagaaaaaac
     3841 caaaacagcc caagttgtgg ctactggaca aggtgttcgt accttgaacg gtgacttggt
     3901 tgctccaagt gttaaaactg gagaccgtgt cttagttgaa gcccacgcag gtcttgatgt
     3961 caaagatggc gatgaaaagt acatcatcgt aggcgaagct aacatcttgg caatcattga
     4021 agaatagaag gagaaagtaa gtatgtcaaa agaaattaaa ttttcatcag atgcccgttc
     4081 agccatggtc cgtggtgtcg atatccttgc agatactgtt aaagtaactt tgggaccaaa
     4141 aggtcgcaat gtcgttcttg aaaaatcatt tggctcacca ttgattacca atgacggtgt
     4201 gactattgcc aaagaaattg aattagaaga ccattttgaa aatatgggtg ccaaattggt
     4261 atcagaagta gcttcaaaaa ccaatgatat cgcaggtgat ggaactacaa ctgcaactgt
     4321 tttgacccaa gcaatcgtcc gtgaaggaat caaaaacgtc acagcaggtg caaatccaat
     4381 cggtattcgt cgtgggattg aaacagcagt tgccgcagca gttgaagctt tgaaaaacaa
     4441 cgccatccct gttgccaata aagaagctat cgctcaagtt gcagccgtat cttctcgttc
     4501 tgaaaaagtt ggtgagtaca tctctgaagc aatggaaaaa gttggcaaag acggtgtcat
     4561 caccatcgaa gagtcacgtg gtatggaaac agagcttgaa gtcgtagaag gaatgcagtt
     4621 tgaccgtggt tacctttcac agtacatggt gacagatagc gaaaaaatgg tggctgacct
     4681 tgaaaatccg tacattttga ttacagacaa gaaaatttcc aatatccaag aaatcttgcc
     4741 acttttggaa agcattctcc aaagcaatcg tccactcttg attattgcgg atgatgtgga
     4801 tggcgaggct cttccaactc ttgttttgaa caagattcgt ggaaccttca acgtagtagc
     4861 agtcaaggca cctggttttg gtgaccgtcg caaagccatg cttgaagata tcgccatctt
     4921 aacaggcgga acagttatca cagaagacct tggtcttgag ttgaaagatg cgacaattga
     4981 agctcttggt caagcagcga gagtgaccgt ggacaaagat agcacggtta ttgtagaagg
     5041 tgcaggaaat cctgaagcga tttctcaccg tgttgcggtt atcaagtctc aaatcgaaac
     5101 tacaacttct gaatttgacc gtgaaaaatt gcaagaacgc ttggccaaat tgtcaggtgg
     5161 tgtagcggtt attaaggtcg gagccgcaac tgaaactgag ttgaaagaaa tgaaactccg
     5221 cattgaagat gccctcaacg ctactcgtgc agctgttgaa gaaggtattg ttgcaggtgg
     5281 tggaacagct cttgccaatg tgattccagc tgttgctacc ttggaattga caggagatga
     5341 agcaacagga cgtaatattg ttctccgtgc tttggaagaa cctgttcgtc aaattgctca
     5401 caatgcagga tttgaaggat ctatcgttat cgatcgtttg aaaaatgctg agcttggtat
     5461 aggattcaac gcagcaactg gcgagtgggt taacatgatt gatcaaggta tcattgatcc
     5521 agttaaagtg agtcgttcag ccctacaaaa tgcagcatct gtagccagct tgattttgac
     5581 aacagaagca gtcgtagcca ataaaccaga accagtagcc ccagctccag caatggatcc
     5641 aagtatgatg ggcgggatga tgtaagcttt ctatagaaaa caacttataa aaaacacaaa
     5701 aggagggaat gactaaccct tctttttata atattcactt ctaaattgat ttgagctctc
     5761 ctaacttata tgataaaata agactagaaa aaggagaaga acatgatcga tgtagaagaa
     5821 attctgtgca agatgacccc caatcagaag attaattatg accgtgtcat gcagaaaatg
     5881 gtacaagcat gggaaaaaaa tgagtagcgg ccaaccattc tcgtgcatgt ttgctgtgcc
     5941 ccttgtagta cctatacact agaatatttg accaagtatg cagatgtgac catctatttt
     6001 gccaattcta atatccatcc caaggcagaa taccataagc gggtctatgt caccaagaaa
     6061 tttgttagtg attttaatga gcggacagga aatacggttc agtacctaga agctccctac
     6121 gaacccaatt aataccgaaa actagttagg gggctagagg aggagcccga aggtggcgac
     6181 cgttgcaagg tttgttttga ctaccgactg gataaaacag cgcaagtggc tatggacttg
     6241 ggctttgact actttggttc agccttgacc atcagtcctc ataagaattc tcaaactatc
     6301 aatagcatcg gaatcgatgt gcaaaaaatt tacacgcccc actatcttcc caacgatttc
     6361 aagaaaaatc aaggctacaa acgttcagta gagatgtgtg aggagtatga tatctatcgt
     6421 caatgttatt gtggctgcgt ctatgcagcc caagcccaga atattgacct ggtttaagtt
     6481 aagaaggacg ccacagcatg cttgttggat aaggatgttg agaaagacta ttctcatatc
     6541 aaatttatag tagattgaaa ctagaatagt acacctttac ttctaaaaca ttgttagaaa
     6601 tcgatttgac tgtccttatt tcattttact atactgttac gaaattagat atataaatga
     6661 aaacttgcct caaggtaggt tttttgctag tagaaaagcg atagacagaa attgttggac
     6721 tcttaaaaaa atgaagtttt gctcaaaaga gctttttaaa ttaaaacgag caattatcag
     6781 ttcaaatctg tttcaaaaga agaacggata aattaatcga tgctttgttt ttgagttagg
     6841 aagttaagca tgccaaactg agtcgtagga ataaatttct ttatagaaat gtgttacaac
     6901 tctgctataa cggaatattc cttttttgca tttatataac ttatttaaca ctatctttat
     6961 tcttgtgata taatgccaaa ttatagagtg gaggtcattt aaaatgattg ataaagtaat
     7021 tgaacaatat aaaagtcatg ataatcttga tattcgagta gaattgcata agaagtattc
     7081 aaaaaataaa ttgggattta ataattggat attttctaac taccaaatca ctgatgaagt
     7141 aaaggttcta gaattgggat gtggtacagg agaattgtgg aaaagtaata gtgattctat
     7201 agataaaatg aagcagttga ttgttacaga tttttctaaa gatatggtaa aatcaacgaa
     7261 gtcagtgatt ggaaatagaa acaatgtcaa ttatgagata atggatattc aaaagatttc
     7321 ttttgagaat gaaacttttg atattgttat tgctaatatg cttctacatc atgtgaatga
     7381 tattcctaaa gctctctctg aggtgaatag ggtcttaaaa accggaggca ttttttactg
     7441 tgctacattt ggtgaaaatg gagttgtaaa ttatttggca agtttattta aagatgaggt
     7501 taatcaagat ttagaaaata gaacgtttac tttacaaaat ggtaaaaggt acctgagtag
     7561 gtattttaac tctgtcgata cattactcta tgatgatgag ttacaggtaa ctagtataga
     7621 tgacctagtt aaatacatcc aatcgtttaa aggaatttca gaaataggtt cactagaaga
     7681 ggaaataata cgtaaaagat tggaaagtga gtttaataat ggtatgttga tcattcctaa
     7741 agaatatggt atgtttatcg ctcgaaaaga aagttaaggg aatgaaagtg tgaaaaatta
     7801 cggagaagct tttcgatatt ttagaaaatt aaacggatat tctttagagt atgctgcagc
     7861 tgattttata tcaaaatctc aactttctag atttgaaagg ggagaaaatg aaatttctct
     7921 ttcaacattt tttgaattat tatcaaatat caatgtttcg atagagaatt tttgtaatca
     7981 cttagaatat tataaaagat cggagcgtga tgattttttg gttaatttat ctccaaattt
     8041 ttatagtttg aatattaaag gattggaggt aataaaaaat aagcaacaaa aactttttga
     8101 gaagagtggg aaaaaactca taaaataaat acaattatgg ttcagggatt atgaaatcag
     8161 ctagattgta atcatgtagt tagtagagat gatctaaatt tagtatatga ctatttattc
     8221 cagaaggaac gatgggagtc ctatgagata acgctgattg gtaatttata tcatcttttt
     8281 gaaatagatt atatttacat ggtcggaaaa gaaatactag agcgtacaca ttattacgaa
     8341 aaaatcggca agaatagaaa tttagttgtg tcagcttgtt taaatttttg gttctgttgc
     8401 cttgaaaatt cacatctaat atatgcagac tactttgaaa tgaaattaca aaaattatta
     8461 aaagatgaca caaaagtttt tgaaaaatct acattcaa
//
LOCUS       DAVLBN010000076         8292 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLBN010000076 DAVLBN010000000
VERSION     DAVLBN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.076"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            146..793
                     /locus_tag="VXC24_001914"
     CDS             146..793
                     /locus_tag="VXC24_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0493985.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            924..1337
                     /locus_tag="VXC24_001915"
     CDS             924..1337
                     /locus_tag="VXC24_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493986.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            1356..1541
                     /locus_tag="VXC24_001916"
     CDS             1356..1541
                     /locus_tag="VXC24_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493987.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(1808..2251)
                     /locus_tag="VXC24_001917"
     CDS             complement(1808..2251)
                     /locus_tag="VXC24_001917"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0493988.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(2281..4503)
                     /locus_tag="VXC24_001918"
     CDS             complement(2281..4503)
                     /locus_tag="VXC24_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0493989.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5519..6148
                     /locus_tag="VXC24_001919"
     CDS             5519..6148
                     /locus_tag="VXC24_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0493990.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VXC24_001920"
     CDS             complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VXC24_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0493991.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         2251 a         1905 c         1590 g         2546 t
ORIGIN      
        1 ttattttcag ggttttattt ctatcatttt attttacttt catttggtgg gagaatattt
       61 gaaaaaaaga aaggtagttt aacctatgaa aaaatcacta aaaatttttg ctacatctaa
      121 atagtttgac ctcttcgggg ttgctttggt cgttgggatt gcgattgcat ctggttacct
      181 caactcacac ctcgataaat ttgtagactg gggatcatgg acagctcttg taccctttgg
      241 attgatttcc gtaaccaacg ttgggatttc catgttgtcc actcgtttca cggggaaatt
      301 aagcaaatgg ggaaattact ttggtattgt taataccatt ttgtccggtg ctattgatta
      361 tatccttgga aataaggcgg ccatcattac ctatcccgtc accttcctca tttatacctt
      421 tgctataaag aagtgggaag cttcgcaaga aggcagaccc aaccaaatga gccaaaaaca
      481 ggtaaaattg gcggccatca tcatttccat catcgccttc ctctttgcct ttgtgaccaa
      541 ctatatcgga tatgggggca agatgaatct ccttgcctac gtaacaacta ttgcctttgc
      601 actgtccctc attgccaatg ctttgaatgc attaaaacta acaactcagt ggggcttttg
      661 gttgatttac aatttcgttc agctgacaaa agctggtatt caaggaaact tcgccaatat
      721 cggtaaatac atcttttata tcctcaatgc aatcggagct ttatttgtct ggaatgatga
      781 agaagttaga taatagaagg aaactcaaat aaagaatact agccaactta agagaatctc
      841 ccttctgcta tttttatcat tttagttgta actcccattc ttttggagta gaatgaagtt
      901 agataaaaga gggaggtctt gtcatgaaaa aactctatag aatccatttt atagcaattg
      961 cagttattga tttgctacta tttgcatttt ttatcactag actcgagaca tcttttgagt
     1021 ggctcttgct ctctggttta attttcttcc ttgctcaagg actcctgcta tttctcttgg
     1081 tcgtccgact caaacatcaa ttcgctgaga tttatcctca aatcaataaa aagattcgct
     1141 tctactattt aggggttctc accattgatt ttctattttt tgttctctta gccttcatta
     1201 gttctcagcg tttttcatct cttatgccaa tcatcactgc ttgccattct actttttatt
     1261 atatgacagc tgactaccta agagaaaact atccagactt ttacgacaaa cacatctctt
     1321 tatgggagtg tctctaagga aaaggaggtt ttagcatgaa aaaaatcatc ttcatcaaaa
     1381 ccattcaact ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaagggggc
     1441 ttacttggga ctggattttg atttatagcg gttggctcat tttctttcat cctgtgctat
     1501 tgacctatct ttcaaaccaa ctttgtgacc actttagtta actctattcc cagattagac
     1561 cgagattctg gcgttttgct ttacaaattc tcctatggga tagcctgatg attctctcct
     1621 tggtgtcttt aagtgatatt ccacttttcc ttcagggaac tctcctcatc ctaggacatc
     1681 tcatcccttc ctatcgcatc tgccaaagcc tgaaaagaga cttcccccaa gcatatcaag
     1741 aaccgatttc tttttggagt attttatgat agatgagaaa gaccaagccg actgggcttg
     1801 gtctttctta tctcttttta gtatctagga taatggtaac aggtccatta ttaaccagct
     1861 caacctgcat atctgctcca aagatgcctg tctgaacggg cacttcttgc gctaattttt
     1921 gattgaaagc atcatagaag tctgatgcca tatcaggttt agctgcccct gtaaaggctg
     1981 gacgattgcc tctcttagta tccgcaaaga gggtaaactg agaaatagag aggatttctc
     2041 cttcaatatc tttgacagac aggttcatct tgccttctgc gtctgaaaaa atccgcatat
     2101 tgaccagttt tctcacagca tagtccaaat cttcctcttg gtcctctggt ccaacaccaa
     2161 ccagcaataa aagtccctga ttgatttttc cctgaatctg gccttctata ctcacttggg
     2221 cttttttaac ccgttggata atgattttca taatagcctt tctagtaaga gctaggacaa
     2281 ctagccgttg gtccgtttga cagagtaaac ttctggcaca ctcttaattt tatcgacaac
     2341 cgtggtcagt gtagagaggt tggcaatacc gaaggacaca tggatattag caaacttcat
     2401 atccttggtt ggttgggcat tgaccgttga aatattcttg gttgtatttg aaagaacttg
     2461 cagtacatcg ttcaacagtc ctgtacggtt gagaccgtag atatcgatat gggccatata
     2521 ctccttattt gagctagggt actggtcttc ccattccaca tcaaggagac gttgctcgta
     2581 gttttcttgg gcacgcaggt tcatacagtc cacacggtga atagccacac cacgaccctt
     2641 ggtaatgtag ccaacaatat cgtcaccagg cacggggtta caacacttag caatccgcac
     2701 taggagacca gaagcacctt caataaccac tcccccctca tgcttgacct tgagggtttc
     2761 tttattttca accttgacct cgccaccttt gacaagctcc tctgcctcag ctttggcctt
     2821 ggcacgctct tcctcacggc gttccttttc agtcagacgg ttaaagacgg taatcgcacc
     2881 gatttcccca aaaccaatgg ccgcaaagag ggagtcttct gtcttgtaac tggtcttttg
     2941 cagaacttga tccatgtggc gcttgtccat aaatttattt gccacatagc cattttcttg
     3001 gaactgagcc atcagcatct cacgaccctt gttgacagac aattccttat cttggttttt
     3061 aaagaactgg cgaatcttat tgcgcgcctt gctagtcttg accatattga gccagtcacg
     3121 gctaggtcca aaggagttcg ggttggcgat aatttcaacc tgatcccctg tctttaactt
     3181 ggttgtcagt ggaaccatgc ggccattgac cttggcacca gttgcttttt caccgacctt
     3241 ggtatggatt tcgtaggcaa aatcaatcgg tcctgaatct ttgggaaggg aacggacagc
     3301 tccatctggg gtaaaaacgt aaatctcctc agccaaatag ttttccttaa cagagtccac
     3361 aaattcctta gcatcatcag cctggtcttg gagctccatc atctccttga tccagttcat
     3421 tccaatagct gattccttgc tgttaacttg cccctttata cctttcttat aagcccagtg
     3481 agccgcaacc ccgtactcag ccacctcgtg catttccttg gttcgaatct ggaattcaat
     3541 cggccctttt ggtccataaa cagtcgtatg gatagactga taaccattgg ccttgcggtt
     3601 ggcgatatag tctttgaagc gacctggcat cggtttccaa aattcatgca cgtaaccaag
     3661 catggcataa acatcacttt gggtatctaa aatacaacga atagcaatca gatcatagat
     3721 ttcctcaaac cgttttctct tgtcctgcat tttgcggaaa attgagtaaa tatgcttggg
     3781 acgaccataa atcttccctt tcaagtgacg ttctgtcgta tactcctcta attttgtgac
     3841 tacctcatcc accaaggcct cacgctccct gcgcttttcc ttcatcatat gggtaatctt
     3901 gtaaaactcc gttggattga gataacggaa agacaagtct tctaattccc atttgacact
     3961 ggaaatcccc aaacgatggg caagcggggc atagatttcc atggtttctt tggaaatacg
     4021 ctcctgcttg tcttttcgaa gatgtttcag ggtccgcata ttgtgcaagc ggtcagacag
     4081 tttgaccaaa ataacgcgga tgtcctcaga catggccatg agcatcttgc gatgattttc
     4141 cgctaattgc tcctcgatcg atttgtactc gaccttgcca agcttggtaa ctccgtcaac
     4201 aatcacccgc acatcaggac caaactctct ttccaaatcg tccaaggtcg catctgtatc
     4261 ttccaccaca tcatgcaaga atccacaagc tactgttaca gcatccagct ttagcttagc
     4321 taaaatacct gccacttgga tagggtgaat gatataaggc tcgcctgatt tgcgatattg
     4381 accactgtgg cattcaacag catagaccaa ggccttatgg acaaaatgaa catcctcttc
     4441 cgttaaatat tctttggtta aagcgacaac ttcttcgcct gttaaattca cttctttcgg
     4501 catctctact ctccaattct tcctaccatt ttatcacttt tttaagaata tgaaaactag
     4561 attggaacag aataagaaaa aaataattca aaattgcttg ataattctga attattggcc
     4621 cataatatac tacgaagtta gattttaaac ttaggtgata gaaggagaga tagaagaacg
     4681 gaaaccatat tgtaacccaa agactttctg atttccccaa ttccattgaa gatacgaaag
     4741 ataaacggtg gaactcgtat cacatacact ggtaccttga ctggattttg gaattaatac
     4801 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa gcactgcttt
     4861 gaggttgtag ataagactga caaagtcagt cacatatata cggcaaggcg acgttgacgc
     4921 ggtttgaaga gattgttgac gcggtttgaa gagatttttg aagagtataa aaatcctcaa
     4981 gatactttct tctatccttt agtttataag gagaatacct atgaaaaaaa ctgctatttc
     5041 tatctttgct ctcctaatgt taggagtttg ctgcctgttc ctattcagcc agcaaagcta
     5101 taaaaaactc gttcaatact atgctaacga ccagaacctg cccagtagga taacttatag
     5161 tgaatatagc gacaaatgat aagccaacta cggtagcact ctaaacatca cgtctatcaa
     5221 acaagctaat gacggagttt atgcaaccta tgaagggcaa ttgacacctt tccaatattg
     5281 ataaattgat aaccagcctg tcttcatcta gtcatgctgg tttttaagtt cattttaaat
     5341 ccttacctat tctccctaac tgtgctatac ttaatttata ctcaatgaaa atcaaagagc
     5401 aaactagaaa gctagccgca ggctgttcaa agcactgctt tgaggttgca gataaagttg
     5461 acgcggtttg aagagatttt cgaagagtat tagtacattc tttgagattg gagctagtat
     5521 gaaaatccat aaaaccgtga atcctgttgc ctatgaaaat acctattatc tagaaggcga
     5581 aaagcacctc atcgtcgtcg atcctggtag tcattgggaa gccattcgtc agacaatcga
     5641 gaagatcaac aaaccgatct gtgctattct cttgacccac gcccattatg accatatcat
     5701 gagtctggac ttggttcgcg agacgtttgg caatcctcct gtctatatcg cagagagcga
     5761 agccagctgg ctctacactc ctgtcgataa tctctccggt ctccctcgcc acgatgatat
     5821 ggcagatgtg gtcacaaaac ctgcagaaca cacctttgtc tttcacgaag aataccaact
     5881 agaggaattt cgttttaagg ttctaccgac cccagggcac tctatcggtg gtgtttccct
     5941 agtctttcct gatgctcacc tagtcttgac gggagatgct ctattccgcg aaactatcgg
     6001 acggaccgac cttccgactg gtagcatgga gcaactcctt catagtatcc agacccaact
     6061 cttcacccta ccaaactacg atgtctatcc aggacatggt ccagctacta ctatcgctca
     6121 cgaaaaggcc ttcaatccct ttttctagca agatgatgac aatcgaaatt taagtaaact
     6181 atccagcaaa tctttctatt acaaaaggca tcctatcaag gttttcacac gtgattggat
     6241 gccttttttc tgatgactag attttttgta ttaccaaata atcacgcgct cctctggtga
     6301 acgccacatt ccgtctcctt ctttgacatc ataggttgta aagaaatcgt cgaagtttgg
     6361 tacttgcaca ttgacacgga gtttggctgg tgcgtgcaca tcgacgctag ccaaaagttt
     6421 cataaattct ggtcgacctt tcatgcgcca gatgcgaccg aagttgtaga agaactcttc
     6481 tgctgagaag tctgcttctc tcttagctgc ttcaagcgct gctgcgattc ctcccaagtc
     6541 agccacgttt tctgatacag tcaatttacc gttaatggtt gctccataag aatcctgtcc
     6601 atcaaattgg tcaatgactt tttgtgtttt ctccttgaag gcagcatagt cgctctctgt
     6661 ccaccaatcc ttgaggctac cattttcgtc aaaggaagcc ccgttagtat caaaggcgtg
     6721 ggaaatttca tgggcaatca ctgccccaat accaccgtag ttagcagaag atgactgatg
     6781 caagtcatag aaaggcgcct gtaaaatggc cgctggaaag acaatcaggt tcttctgagg
     6841 attgtagtag gcattgacca tatgagcagg catgccccat tccttatagt ctacaggctg
     6901 gttccactta ctccaactgt gcttgatttc cacacgcgca aaggctagag cattctcaaa
     6961 aagactggca gtttcattca ctaccttatc cttgtaacgt gcaggcaatt cttctggata
     7021 gccaatataa ggtttgatca cattgagctt cacgatagcc tgtttacagg tttctggagt
     7081 gagccagtca ttcttaagca gacgctcctt atagacatca atcatggttg ccactttttt
     7141 ctccacatcc gccttggctt ctggagagaa cttctcacgg gcgtaccaaa gacccagggc
     7201 ttgcttgaaa ggttcttgtg ctagatgata agctgctttg accttatctt ttgcctctgg
     7261 aactccagaa agggcacggc tgtaggcacc agacaaaaca cggatatcct ctgttaaata
     7321 gctggttgaa agattgacaa cactcaaaat caaggttgct ttaaggagag accaggcttc
     7381 ctcactgtag aattgctctg ctgcttgcca gaaacgttcc tcgtctacaa taaccttgtc
     7441 tggtaattgc ccaataactg ctttgaagaa gtcatccaaa ggtagggcag gcgcgaattt
     7501 cttaaaatct tcgtaagaat atggatgata gagtttagca tattctgaac tttcttcatt
     7561 agagagcacc actgccgcaa ctcggcggtc caattcaagt cttttttcta gcaagtcttc
     7621 aatttcttca tcagagaaat cataagcctt gaggagattt gcgctgcttt ctttccaaag
     7681 agtcaagagc tcttcgcgct gaggatgttc ttctgcatag taggtcgtat ctggcaagat
     7741 tgtgcttgga gcgctagccc atagaacatt gattctagca tccataaagt ctggcgatac
     7801 accaaaagga aggaagtttg gttttcctgc aagctcaaac tctgctagtt tagctgtaaa
     7861 atccgcaaaa gtttccaatt cttggaattc tttaaggagt ggtaagacag gtgtgatacc
     7921 gtcagcttct ctcttgtcaa aatcacgaac taggcggtgg tatttgacaa agttttccaa
     7981 gatagcatcc tcaggcactt cttcacctgc taaccacttg tctgttgtcg ccagcatcag
     8041 gtcttcaatt tcctggtcta aatcaacaaa acctccagtt tgagacttat ctgctgggat
     8101 ttcagctgtc tgttgccatt ctccattgat agcatcataa aaatcatctt gataacgtgt
     8161 catcttgttc tcgctttcat ttgtatttgc atttatctta acaaaaatca ctagggaatg
     8221 caattaataa ccatttaact attatttttt agctattata aaaaatcttt ccatgataaa
     8281 acgcataatt cc
//
LOCUS       DAVLBN010000077         7996 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLBN010000077 DAVLBN010000000
VERSION     DAVLBN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.077"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..330
                     /locus_tag="VXC24_001921"
     CDS             <1..330
                     /locus_tag="VXC24_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV0493992.1"
                     /translation="QIIADSAESRLIEELRSEHGISRIKESRKGKDSIMAGVSKLQGY
                     AIYVHPDCKNIMDEFYSYCYQRDKEGNWLNKPEDKNNHLMDALRYSLQCIEGGKATVR
                     RRSDYGL"
     gene            342..1811
                     /locus_tag="VXC24_001922"
     CDS             342..1811
                     /locus_tag="VXC24_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0493993.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            1720..2751
                     /locus_tag="VXC24_001923"
                     /pseudo
     CDS             1720..2751
                     /locus_tag="VXC24_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            3111..3338
                     /locus_tag="VXC24_001924"
     CDS             3111..3338
                     /locus_tag="VXC24_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HEV0493994.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            3487..3699
                     /locus_tag="VXC24_001925"
     CDS             3487..3699
                     /locus_tag="VXC24_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493995.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            3869..4453
                     /locus_tag="VXC24_001926"
     CDS             3869..4453
                     /locus_tag="VXC24_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0493996.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            4460..5305
                     /locus_tag="VXC24_001927"
     CDS             4460..5305
                     /locus_tag="VXC24_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0493997.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            5317..5499
                     /locus_tag="VXC24_001928"
     CDS             5317..5499
                     /locus_tag="VXC24_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0493998.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            5489..5677
                     /locus_tag="VXC24_001929"
     CDS             5489..5677
                     /locus_tag="VXC24_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0493999.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            5679..5990
                     /locus_tag="VXC24_001930"
     CDS             5679..5990
                     /locus_tag="VXC24_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0494000.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            5971..6309
                     /locus_tag="VXC24_001931"
     CDS             5971..6309
                     /locus_tag="VXC24_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494001.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            6284..6799
                     /locus_tag="VXC24_001932"
     CDS             6284..6799
                     /locus_tag="VXC24_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0494002.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            6796..7164
                     /locus_tag="VXC24_001933"
     CDS             6796..7164
                     /locus_tag="VXC24_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494003.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            7167..7580
                     /locus_tag="VXC24_001934"
     CDS             7167..7580
                     /locus_tag="VXC24_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0494004.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            7585..7965
                     /locus_tag="VXC24_001935"
     CDS             7585..7965
                     /locus_tag="VXC24_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494005.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
BASE COUNT         2654 a         1423 c         1881 g         2038 t
ORIGIN      
        1 caaatcattg ctgatagcgc agagtcacgg ctgattgaag agctcaggtc agaacatggc
       61 atatctagaa taaaagagag tcggaaaggt aaggatagta ttatggcagg cgtatccaaa
      121 ttgcaaggat acgctattta tgtgcatcca gattgtaaaa acatcatgga tgaattttat
      181 agttactgct accagcgaga taaagaaggc aactggttga ataaaccaga ggataaaaac
      241 aaccacttga tggacgcttt gcgttacagc cttcaatgta tcgaaggtgg aaaagcaacc
      301 gtccgcagac gttctgatta tggtctatag agaggaaaga catgtaccaa tatttaacct
      361 atccacggga tggatatgat gagggttctt tgaagaaaga cctgatttac aaattgataa
      421 cgatacataa cactgaaagc tcacgcttga agaatttaaa aagctactac atgggtgatc
      481 atgctatttt aaatcacaag agacgcaacg tgaacgcacc caattacaag acggtagcta
      541 atcatgccaa ggatatcgca gacacggcta cgggctattt tatgggcaat cctatcaagt
      601 ataacaatac tgctgacggt gatattgatg aactacttac agcctttgat ggtgctgaga
      661 ttgaccaagt ggatgcgcag aacgcactaa atatggctat ctacggccgt gcttacgagt
      721 acatctatgc taaagagggt atgactgagt tggattcaac tagtattgat ccggagaata
      781 ctttcatggt ctacgatgat agtattgagc ggaagccttt gtttgcggtc tattactatg
      841 aagtaaaaga cgatacgaaa gacactacca agcaccaggc tgaggtcttt accgaaaatc
      901 tgcactatca catggtgctg agaagtacag attcaggaac aactcagagc gaggaggcaa
      961 cacctcacaa ccttggtcaa atcccaatta tcgagtatcg caataatcac tttgcgattg
     1021 gcgactacga gcaacaaatt agcttgatag acgcttataa ttccttgatg gggaatcgtg
     1081 tcaatgataa ggaacaggct gtagagtcta tccttgtctt gtatggcacg cagttagcag
     1141 acactccaga agacgctaag gtagcaatga agattctttc tgaagaaggt cttttggaat
     1201 tgccgggcga tagtgcaagg gctgagttct tgaagaatac gctggacgaa agtgctactg
     1261 aaatcttgcg tacagctctt aaagaggaca tctacacatt tagccatgtg cctaatttga
     1321 ctgatgagaa tttcgcaggg aatacatcag gcgtagccat ggaatttaag ctgatgggcc
     1381 ttgagatgat tactaagacc aaggaagcga actataagcg aggattgcgt cagcgtattg
     1441 cgatttttgc tcattactta ggcatgaagc agattgcttt agagtctcat tcaatcgttc
     1501 cacaattcag tcgtggtttg cctaagaact tattagaaat ctctcagatt gtgaacaatt
     1561 tggaaggcaa agtgaccaat agacagctta tttctctctt gccgtttgtg gaagaccctg
     1621 acgctgagct ggaagccttg gaagaagaga aaaagaagaa catggaagac atgccgatgt
     1681 tcaacaaaga caacacgaaa cccgaagacg aggtagagga tgaagaatca ggagtattgg
     1741 gcgaagagga aagccaatct gatttaccag cagatggaca aggccgaaaa gcaggcagac
     1801 cagttcgata aggtctatca ggaagctaag acttacttgg ataaggaaat caataagatt
     1861 ttcgataaat tccaacgtga ttatggtcta agtcaggtag aagctagaca agtcttgaag
     1921 aacatgaaag acaagaaaaa tctgaatgaa cttcgtaaag tacttgaagc gagaccgaat
     1981 gacccgaaca tccaaagatt actagctgac ttagacagcc cagcttattc tttccgcatg
     2041 aagcgcctag agcgtttgag cgacgattta gatcgtatgc gtgaatctat ctatcattcg
     2101 gagaagacag gctcagatgc cttttatagc gacctgatga aggatagtta ctacaaggct
     2161 acctttgacc tacaacagca gacaggacta gcatatggct tttctgggct tcctgagaac
     2221 gagattaaac atctacagtc ttttagttgg gtaggagatg gaagtacgta ctcaacagac
     2281 atctggaaga atacaggaaa acttacttcc agcataaaag atgaactcct cattagcctc
     2341 atgacaggca gagatacacg agaaactgca caagcaattg ctgagaggtt caatgtaggt
     2401 cagaacgatg caaggcgttt ggttcgaaca gaatccgcct tttttcataa ccagatggag
     2461 ctactcagct atgaagaagc agacatagaa aagtatatct ttgtggccgt cttagacaag
     2521 cgtacatcac gcatttgtca ggagcatgac aatcaggtct atgataggga taaggctgtc
     2581 cctggtgtca attgtccgcc tatgcaccct tggtgtaggt ctactactgt cggatacgat
     2641 gaggacgcag actacagcaa gttgaagcgc agagcaagga atccagagac aggtaaagtt
     2701 gagtacgtgc ctgccgatat gacttataaa gagtggtata gcaagtatgt ggatggtaat
     2761 agagagtcta ttaaacgtaa agcgtttgat aaaactatta aagatggtat aatagtaagt
     2821 gtatcaggga ctacaattgg acacactccg cctggcaaaa taggtttgcc taatagtgta
     2881 gttcagcata atgctacaaa cggagatgtc cttggtagaa cttactatga tgctagaggt
     2941 tttaaaacga aagatgttca ttttacaaac cataaacaac cggcacgtca tccttatgga
     3001 aaaatcggag aacatgctca tgattttgta tttgatgatg aaggtaagtt cgttagtagg
     3061 agtactaggg aattaacaga cgatgaaaga aaggagaatc aagatatatt atggcgatat
     3121 tagatgattt acaagcgtta tatgataatg gatgggacgc ttcttttaat tataatggtc
     3181 aagtatgtgg cattttccct aattctattt atgatgttgt tgttattatt gcggacgacg
     3241 aatatagagc atcttctttt gacgatttga tttctttaca gattgaaggg aaaactttac
     3301 cggaaatcat gaacgaagtt gaagtacaat atggctaaag cacctagaga gatctaagtg
     3361 cttttttagt acccagaaag gagactatcc gtacgatttt cttgattgtg aatttgaagt
     3421 aaaaagaatt tcagtgatag cttgcgatac tatccttata gaagcctaaa agaaaggaac
     3481 agaaaaatgg aagaatggaa agaaagattt aaaaaagaat actacgaatt gaaagaacga
     3541 ttccagaagt tagatatgat gattgggaaa tacgaaaaag ggcaactaga gtttgaatct
     3601 aaatgtccga ttgattcgtt aaaaggtcag cgttcaacca tgtggaatta tttaagaatt
     3661 ctagaacaac gtgcaaaaat tgaagaaatt aaactataaa aattaaccgc atcgaaatcg
     3721 atgcggtttt cctatgccct aaccgtatgg aatcccgtac ggtttttata ttgtccaaac
     3781 tgtaccgatg acaataaaag ctgtgctgtt ccgtcgccgg acgtaaaacg agattatcga
     3841 gtggcgacgt aatcgctgga ggacaattat gtcagaagaa atcaatgcaa ctgtatctac
     3901 tgaatcaact gagactgtcg acactcaagg aaatgttgat tcagtgcagg aagaaaagca
     3961 cgaacgaact ttcactcgtg ctgaaatcgg taagatgcta tctgccgaac gctctaaatg
     4021 ggaagctgag caagaagcca aggaaaacga agctaagaaa cttgccaaga tgaacgctga
     4081 cgagaaacaa aaatatcagt tggatcagcg tgagcaagaa ctagctgacc gtgagaaggc
     4141 tattgctcgc aaggaattga ccgcagaagc taaagcaatg ctaagtgaac gtgacttacc
     4201 tgttgagtta gtaaatgtag ttgatttgac aagcgcagag acggtatcgc agtctgtcgc
     4261 tgtattgcag aaatcatggg agcaagccgt gcaaaaaggc gttcaagaaa aactaaaagg
     4321 cggagctcca atgaaacaag cgccagtcga tagtgacggt atcacaaaag aagaatttgc
     4381 tcgtatgggt tatcagagtc gaaatgagct ctatcaaaag aacccagagc tttataagaa
     4441 attgaaagga taatagaaaa tgacagcagg acaaactaaa ttagccacta tggttaatcc
     4501 agaagtaatg gcggatatgg tagccgctaa attacctaaa ttgattaaat ttacaccgct
     4561 agcgtatgta gagacaaagc ttgaaggtca accaggtagc actttaacag tgccagcatg
     4621 ggagtatgca ggagacgcta ctgaaattga agaaggccaa gcaattacgc cagaccaatt
     4681 gactactaaa aagactacta tgaccatcaa aaaagcaggt aaaggttatg aaattaccga
     4741 tgagtctctt ttgtcaggtc ttggtgaccc actaggtcaa gcgacttacc agcttggttt
     4801 agctattgcc aacaagatcg ataatgattt ggtagcggta gctaaaactg caacacaaca
     4861 tattacagaa actccaacaa ctcttgaggc aatcgataaa gctctagata tctttgagga
     4921 cgaagaagat gcacagtatg ttgctatcat caaccctaaa gatgctacta agctaaaaac
     4981 tgcagtagca aaagaatgga ttaaaggttc agagcttgga gcaaatatgg ttgtttctgg
     5041 aaccttcggt gaagttgatg gtgtgcaaat cgtgcgctct aaaaaagttg atgaaggtaa
     5101 aggcttcctt gttaaagtgt caccaagtca aactcagaca gacgacgcta acaaatatgg
     5161 agcttttgtt atcttgctta aacgtgatgt ggctatcgaa acagaccgcg atatcttgaa
     5221 gaagactacc gtaatcacag gtgatgaaca ctacggcgtt tacctttacg accctacacg
     5281 agttgtaaaa ttcggtggcg cgtaagaggt gacgatatga gtttattgct acgacgtcat
     5341 tatattcaag aagagcaggt taaccagtat tctgatttag agaataaaac tctagaagag
     5401 ttgaaggatc tagcgaaaga agcaggtgta gcaggcgctt ataagttgac aaaagccgaa
     5461 attgtagaag ttttggagga actaaaaagt gaaatttaaa atcaaacaag atttctatga
     5521 ttgggaatca aatgtgaaac gactggcagg agaggaactt gagattactg aggagcgcta
     5581 tgctgagctg gctgacaata ttgccagcaa cggtgtcact atctcagacg ttcttgagaa
     5641 aatcctccct gaacctgagt tcttagaaga ggattgatat gtctatagag ttgctgaaga
     5701 aattaacagg cgaagaagat actcagcttc tcatgttgct ccaaacgagg gctacaaatc
     5761 ttatcttgtc agagactaat cgcacatctt tgacacctgc tttaagtctt ttaatacctg
     5821 aggttgctat cgaactccac aaccgctcag gagcggaagg agagcattct agaaccgagg
     5881 gtggtatagc agtagtctac ggagaaaacg gcctgtctac ggatcttcta cagcgaatac
     5941 gcatgcacag gctagcaagg gtggcaggtc atgtttttga agcagagtag actgaaacct
     6001 tatccaatgc gacggtttga aaagactgtc actgaggaag gtgtcgcgaa agaagggtat
     6061 gccaaggaag ctgagacagt ccgccttgaa ttgtggccag ctagtagcaa gctacaatct
     6121 gaattgtatg gcgagcgtgt caatgatatt ttgaacgcaa atgccaacaa gtcagctact
     6181 atcaaagtaa aagatggtgt gtgtatcgat agtcagacgg aagtgactca tagggttatt
     6241 tctaaaaagg tctacacaca tcatcaagtt ttggagttag agcgtgtcag ggctactagg
     6301 ggcagatagg cttatagcta aatgtagacg attggctagt aaaaaaactg gcgaggatat
     6361 cgtcttacgt gcggtgcaca atgctactat aaaggttgtc caagcagatg caagaagact
     6421 cgcaccagcg agagatggag agcttataac tagtatcaaa actagggcaa aaatggacgg
     6481 agataaggct ataggcgaag tttacaccaa ccttaaatac gctccttatg ttgagtttgg
     6541 aacgggacca ataggacaag ctagccattc tggtatttct ccagaggtca gcgtgactta
     6601 caagtctagt ccgtggtatg tacatgaaga ccaaatcaat gtaggaccgt accactttca
     6661 aaaaatcggg gagttctaca agatgtatgg tcaacctgcc cagccttatc tttatccagc
     6721 tttgagagac aatcaagagc gtgtgtctaa gaatatttcg aattatgtcc gtagaaagat
     6781 aagagaacaa ataaaatgat taatatcaag cctgttattt ataaagaatt gcaaaaggtt
     6841 gcagataatg tgaccgatac ttatcctagc gattgggaga ctttcccagt cgttattttt
     6901 ttggaagaac aaaacaagcc gggtgattgg tttgatgacc aggaacaaaa atcctctatc
     6961 cgctacaagg tggatatctt tgatgatact agcactagtg agttagctgt taaaatcaat
     7021 cagatttttg agtctttagg tttgcgaaga actgactgcc aagacgtgcc agacccgtct
     7081 catttgagac ataaggtcat gcgttttgaa ggtatcgtcg acttacactc agagcttgtt
     7141 tttcaattta gaatggagaa ttaaacatgt tagcaaatgg aattacgctt tcttatggcg
     7201 aaacaaaaga tagctatact aaacttgttg gattgaaaga agtaccagag tttggtattg
     7261 aactcgaaaa agtagaaaat actactcttg aagatacggt gaagaagtac gagtttggta
     7321 ttggggacat aggagaactt gagtacaagt tctcttataa taattcaagc gcaactgctc
     7381 cttatcgtgt attgcgtaag gcagcagacg acaagaagaa actctacttt gaacaagctt
     7441 atccagacgg tactaaggtc atttttgaag gccaagtatc tgttaagctt ggcggtggcg
     7501 gtgtcaatgc cgttatcgat ttcacactta agattgcctt gcagtctaat cttacattta
     7561 ctgatggtat tggaggttaa ttaaatggcg ttaaaataca caacttggaa agttactgac
     7621 gaaaaagagt tgaagctacg tttgacatct catcaagctg caactgtgga agaaaaaatc
     7681 ggcatgaact tgctgaagat tttcatgcct gaagctggcg aagagttcac tttaccgcct
     7741 ttgaaagtta tgttgttgtt agttcacgga gccttgcagc agtatgaaca tgggtattct
     7801 cttgaggatg tctatgattt atacgatgaa tacgtggaca atggcggaga ccaaacaacc
     7861 ttcatgacag aggtgttgat gccactcttt gaagtatcgg gttttactcc acgaggaagc
     7921 aaggacaaga aaacttccaa gaagaaaatg acagtagaca agtaatctta acggtaactc
     7981 agattattga gaggct
//
LOCUS       DAVLBN010000078         7915 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLBN010000078 DAVLBN010000000
VERSION     DAVLBN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.078"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(172..2169)
                     /gene="metG"
                     /locus_tag="VXC24_001936"
     CDS             complement(172..2169)
                     /gene="metG"
                     /locus_tag="VXC24_001936"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0494006.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2293..3552)
                     /locus_tag="VXC24_001937"
     CDS             complement(2293..3552)
                     /locus_tag="VXC24_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0494007.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3554..4255)
                     /locus_tag="VXC24_001938"
     CDS             complement(3554..4255)
                     /locus_tag="VXC24_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494008.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4239..5438)
                     /locus_tag="VXC24_001939"
     CDS             complement(4239..5438)
                     /locus_tag="VXC24_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0494009.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5724..7070
                     /gene="gor"
                     /locus_tag="VXC24_001940"
     CDS             5724..7070
                     /gene="gor"
                     /locus_tag="VXC24_001940"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0494010.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7267..7803
                     /locus_tag="VXC24_001941"
     CDS             7267..7803
                     /locus_tag="VXC24_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0494011.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT         2252 a         1761 c         1500 g         2402 t
ORIGIN      
        1 tcagtttcat ctacaacctc aaagcagtgc tttgagctga cttcgtcagt ttcatctaca
       61 acctcaaagc agtgctttga tcaacccgcg gctagcttcc tagtttgctc tttgattttc
      121 attgagtata aataaaaaaa cagaactagc ctgaactagt cctgtctact tttacccaat
      181 cacacttcca tttggtacag ctggatcaac tgtgagaagg gttaatttgc catcatgttc
      241 agctgagaga atcataccct ggctgacata ttttttcatc attttacgtg gtttgaggtt
      301 agcaacgatt tgaactttct tgccgaccaa ttcttgttca tttggatagt attttgcaat
      361 tcctgaaaga atctgacgat cttctccatc accagcatcc aagcggaatt gaagcaactt
      421 atctgaacct tctactttag acacttcttt gacttctgcg acacggattt caaccttgtc
      481 aaagtcttca aacttgattt catccttgtt tagtttgagc tcaacttcgt ccggattcca
      541 ttctttttcg actgctggtt tattgccttc catttgttcc ttgatatagg cgatttcttc
      601 ttccatattt agacgtggaa agataggtgt tcctttggca actacagtca catctgctgg
      661 gaagtcagcc aaactcaagt tttcaagact agaaacttct tccaaaccaa gttgagtcaa
      721 aactgcacga ctagtttcca tcataaatgg ttcaatcaag tgagcaacta cacgaatgct
      781 ggctgccaag tggctcatga cacttgccaa ttggtcacga agagcttcat ccttgtccaa
      841 gacccatggt gcagtctcat cgatgtattt attggtacga gagatcagag tccagactgc
      901 ttcaagcgca cgtggatagt caactgcttc catgtgtgta tggaagtctg cgattgattg
      961 ttctgcaacc tcagcaagaa catgatcaaa ttcagtcaca ccttctacat aggcagggat
     1021 ttgtccatca aagtacttat taatcatgga aaccgtacgg ttaaggaggt tcccaaggtc
     1081 attagccaat tcatagttga tacggccgac atagtcttca ggagtaaagg ttccgtctga
     1141 accaactgga aggttacgca tgaggtagta acgaagtgga tctagtccat aacgctctac
     1201 caacatttca gggtaaacga cattcccttt tgacttagac atttttccgt ctttcatgac
     1261 aaaccaacca tgggcaatca aacgatcagg taatttaaca tccaacatca taagaaggat
     1321 tggccagtag atagagtgga agcgaaggat atcttttcct accatatgga agactgttcc
     1381 attccagaac ttgtcaaagt taccatgttc gtcttgagcg tagccaagag ctgtcgcata
     1441 gttaagaagg gcatcaatcc aaacgtagac aacgtgtttt ggatttgatg ggacaggcac
     1501 tccccatgta aaggttgtac gagataccgc caaatcttcc aaacctggct cgatgaagtt
     1561 gcgtagcatt tcattaaggc gaccatctgg cgtgataaat tcaggatgag ctttgaaaaa
     1621 ttcgaccaaa cggtcttggt atttgctaag gcgaaggaag tatgattctt cagaaaccca
     1681 ttcaacctca tgacctgatg gagcaatacc accagtcaca tttccagctt catcacggaa
     1741 aacttctgcc agctggcttt ctgtaaagaa ttcttcgtct gatactgaat accaaccaga
     1801 gtattcaccc aagtagatat catcttgagc aagtaagcgt tcaaagacct gtgcaacaac
     1861 tttttcatgg tagtcatcag ttgtacggat aaatttatcg tatgagatat ctagtaattg
     1921 ccagagttct ttaactccaa ccgccattcc atcaacatag gcttgaggtg taataccagc
     1981 ttcttccgct ttctgctgga ttttctgacc atgttcatca agacctgtca gataaaatac
     2041 atcgtagccc atcaggcgtt tgtaacgtgc taggacatca catgcgatag ttgtgtaggc
     2101 agaaccgata tgaagtttcc cagatggata gtaaatcggc gttgtaatat aaaaattttt
     2161 ttcagacata atttttcctt tccaggcaaa tgaaacctgt ttttctaaca cttcattata
     2221 tcacattttt aatgaatttc gatagggaaa tccatacaaa aacaagatag acgagtgtcc
     2281 atcttgttga tctcattcat aacgaagggc ttcaattgga tcaagtttcg atgccttgtt
     2341 ggctggcaag actccaaaaa tcataccaac actagccgaa actgcaagac taaatagggc
     2401 aactgggatt gatactccaa cttctatacc ttctattaaa ccttgcagta acaaacctgc
     2461 taaggcagtt aaaccacttg caattgtcaa gccaattaag ccacctaaca aggtcaaaat
     2521 catggattca atcaaaaact gaattaaaat attggcacgt gttgcgccca aagccttacg
     2581 aagaccaatc tcacgagtgc gctctgtcac cgaaaccagc atgatgttca tgacaccagt
     2641 tcctccaaca aagagagaaa tccctgcgat ggaactaata atcgtcgtca taaaactaaa
     2701 cgattgttga atttctgcaa atacaacgga ctcatctgcc acctggtatt ctccctgttg
     2761 taagcctgca agctctgtca tttttcgtgc cagttctgga cccagagttg gggttaaact
     2821 ggtatcattc actcgaaaga caatattagc tatttcatct acattaaaat tcgcagcaag
     2881 ggagatattg gtagtaatag gcaagccacc aaacccatat atttttgatc ttttagcctc
     2941 cggactagta taaaccccaa tgacccggta actaaatcca ttgacttcta caaccttgtt
     3001 aatagcctct tgaggagatt caaataaact aatggacaat tcctcatcta gcaaaatgac
     3061 acttgcaaac tctttgaaat cttgctctct cagactacga cctgcaataa tttcattctt
     3121 aacagcgtcc atgtaagttc tgtttccacc tgtcaaatta gcattctcaa cctttttatc
     3181 ttgataggtc aagatggcat tcgttgaatt ggttacatag taactatcca ctcccttcag
     3241 tttagctgcc tcttggaccc aggattcttg cggttttggc ggttcaacag gaacttcctc
     3301 ttcctttcca gaaaccgtaa aagctgattg tttctgagta aaagacccgt ctttactttt
     3361 tttaggagaa aaaaagacgc taatattttt ctgagattta gtcatatctt tattgacttg
     3421 acgagatagg gaatcaccca aagccataat cacaacaact gatgaaacac cgataataat
     3481 cccaatcata gtaagcaaag aacgcatctt gtgagccatg atagatgaaa aggcaaattt
     3541 cagattctgc atcttagttt tcctcctttc ctaactgagc actgtcagac gaaatgaccc
     3601 catcccgaat gacaatctga cgtttggcat aggcagcaat ctcaggctca tgcgttacca
     3661 tgataatggt ttttccttct ttattcaaat caaccaataa ttgcataatt tggttacctg
     3721 ttttggtatc caaggctcct gtcggttcat ccgctaggat aatagaagga ttgtttacca
     3781 aggcacgcgc aatggctaca cgttgctttt gaccaccaga taattctgaa ggtaaatggt
     3841 gactacgttc tgtcaattca accttgtcta aatattcctc agccaacttg cgacgttttg
     3901 aagacgaaac tcctgcgtaa atcaagggca attctacatt ttgcagagca ttgagcttcg
     3961 atagaagaaa gaactgctga aagacaaaac cgatttgttg gttacggacc ttagctagtt
     4021 gtttttcacc cagcccagcc acttcttgac cttcaagata atattctcca ctggttggtg
     4081 tatccaacat gccaatcgta ttcatcagag tggacttacc agacccagat ggtcccatga
     4141 tggctacaaa ttcaccctca ttcacttcta gattgatatt tttgagaacc tgcagttctt
     4201 ggtcaccatt acggtaactt ctgaagatat tttttagact aattagttgc ttcatcagcc
     4261 ttcacctctt ttccttcttc caaggaagat gttggattac tgatgacctt agcaccgttc
     4321 gttaaaccag aagtgatttc ttgattttct gcgtcagcat ttcccaatga aacctcaact
     4381 tttttagcct tttgttgttc atccacaatc cagacataat ttttactatc atccattact
     4441 agactgctaa caggaacaag aatagcctta gttttgcttt taacctcaat gttgacagaa
     4501 aaaccttgtt tcaaatcacc aacctcgcct gtcacatcaa tagtataagg gtatttagaa
     4561 cctgtattat tcccggctgc tggactagct gcttcaccat tgtttttagg atagtcagaa
     4621 atatagctta atttcccagt ccatttttta tcaggataca ctttagaagt aaagcttact
     4681 tcttgaccta cagaaaggtt ggctagattg tactcagaca attctccctt gacttgtaaa
     4741 ttttcattgc tgacaatatg aaccataact tggctcgccc ctgttggaga tttagaaaca
     4801 ttgctattga cttcgactac agttccctct agggtactga gaacagttgt tgcatccaat
     4861 tgactttgag ccttgcttaa ttgcgccgca gcatctgcac gcgcatcacg ggcatcaccc
     4921 aattgagcat caatagaagc aacagaattt ccagccactg gagttgggct ttgcaccgtt
     4981 gcatcttctc ctcctactgg cgctggtaac tgtggagccg gagctgaagc ggcttcattt
     5041 cgtgcttgat tgagttcatt gatatgacga tctgccctag ctactgctcg actagctgaa
     5101 tcataggccg cctgcgcttc tgaactactg tacttgacta aagcctgccc ttcgctgacc
     5161 ttatcgccca cagaaacaag gatttcatct aaatcaccct tactagcatc aaaataaaca
     5221 tattgttcat tttttgctgt tactgtccct gacaataaaa cagaggatgc cacgcttcct
     5281 tccttggcaa caacaagatg agtaggctca tcttttagag cagtctgaga aggttgtcta
     5341 aaaagtaaaa tccccccggc acccaataca actacactcg cagcaccgat tgctgcatac
     5401 agttgccact ttttagcttt accattcttt ttcttcataa tgaaactcct tttctttttt
     5461 acaatacttt gctattatac caaatttccc tccagcaaac aatgcagttc agatggaaat
     5521 aatggcagtt caggattaaa caatcgttcg gaattttgct tttctattgt actagatata
     5581 taatacacta tcttgactta tttggcaagc ttttttgcaa ttttttgtgc gtagcagatt
     5641 tttgcaatca aatcaaaaaa agaataaaat ataactatca aaaaagacgc tctactattt
     5701 aaaagattac aaaggagttt tcaatgagag aatatgatat cattgctatc ggtggaggta
     5761 gcggaggaat cgctaccatg aaccgtgctg gtgaacatgg agccaaagca gccgttattg
     5821 aggaaaagaa attaggtgga acctgtgtca acgtcggttg tgttcctaaa aaaatcatgt
     5881 ggtacggggc gcaaatcgct gagactttcc atcaatttgg agaagactac ggctttaaga
     5941 ctactgatct taactttgac tttgcaaccc tacgtcgcaa tcgtgaagcc tacattgatc
     6001 gcgctcgttc ttcttatgat ggtagtttta aacgcaacgg tgtagacttg attgaaggtc
     6061 atgctgaatt tgtagattct catactgtaa gcgtaaatgg tgaactgatt cgtgctaaac
     6121 atatcgtgat tgctacaggt gcccatccaa gtattcctaa tattcctggt gctgagctag
     6181 gtggctcttc tgatgatgta tttgcctggg aagaacttcc agagtcagtt gccattctag
     6241 gcgctggtta tatcgccgtt gaattagctg gcgtactcca cacttttggt gtcaagacag
     6301 atctctttgt tcgccgcgat cgtcctttac gtggttttga ttcctacatc gttgaaggtt
     6361 tggtcaagga aatggaaaga acaaacttac cacttcacac tcacaaagtc cctgtcaagt
     6421 tagaaaaaac tactgacggc attaccattc atttcgaaga tggtactagt cacacagcta
     6481 gccaagttat ctgggctaca ggccgccgtc caaacgttaa gggcttgcaa cttgaaaaag
     6541 ctggagtgac tctgaacgaa cgtggcttta tccaagtgga tgaataccaa aatactgttg
     6601 ttgagggact ctatgctcta ggtgatgtaa cgggcgagaa agaactgact ccagttgcaa
     6661 tcaaggccgg acgtacccta tctgaacgtc tctttaacgg aaaaactact gcaaaaatgg
     6721 attactcaac tattccaact gttgtctttt cacaccctgc tatcggaact gttggtttga
     6781 cagaagagca agctattaaa gaatacggtc aagaccaaat caaggtttat aaatcaagct
     6841 ttgcatctat gtactctgct tgcactcgca accgtcaaga atcccgtttc aaactcataa
     6901 cagctggttc agaagaaaaa gttgtcggac ttcatggaat tggctacggc gttgatgaaa
     6961 tgattcaggg atttgccgtt gctatcaaaa tgggagcaac caaggctgac tttgatgcaa
     7021 ctgtggcaat tcacccaact gcatctgaag aatttgtaac catgcgttaa tcgaaacaaa
     7081 agaagctgat ataaatatgt ctgcttcttt tttaatgatt ttcgaatcaa caaaaaaatt
     7141 atccaacttg actagtcacg aaaatcggct gttacagttt ttgttacctt gtttttaaaa
     7201 aatggttgac atcgactcct atatgagtat aatagttact atacattaga aaagaggtta
     7261 actattttga aaaaagctca cgtttatgct atccctgcta ttggggctgc tctcattgct
     7321 gctttggcac aaatcagtct tccaattgga cctgttccct tcactctgca aaactttgca
     7381 atcggcttga ttgctactgt ctttagaccg agagaggctg tactttctgc tggactctat
     7441 cttcttctag gtgctatcgg tcttcctgtc tttgcaggag gtggagctgg ttttcaggct
     7501 ttagttggcc ctactgcagg ctatctttgg ttttatctcg tttactctgg acttacttcc
     7561 tctctaacca acagcaagag tggtgttgtt aagatttttc ttgcaaacct cttgggtgat
     7621 gcccttgtct ttgtcggcgg gattctcagc ttgcatttcc tagctggaat ggcatttgaa
     7681 aaagctcttg ttgtgggggt tcttcccttt atcattccag accttggcaa acttctggct
     7741 attagtttta ttagccgtcc cctacttcaa cgccttaaaa atcaggctta ctttactaac
     7801 taaaaaagga taccgagtta tcatgactca atatcctttt cttttatttt gaaaacttat
     7861 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca aaaca
//
LOCUS       DAVLBN010000079         7817 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLBN010000079 DAVLBN010000000
VERSION     DAVLBN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.079"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(177..1592)
                     /locus_tag="VXC24_001942"
     CDS             complement(177..1592)
                     /locus_tag="VXC24_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0494012.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VXC24_001943"
     CDS             complement(1605..3443)
                     /locus_tag="VXC24_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0494013.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4303)
                     /locus_tag="VXC24_001944"
     CDS             complement(3461..4303)
                     /locus_tag="VXC24_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0494014.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLT
                     KNLD"
     gene            complement(4603..7281)
                     /locus_tag="VXC24_001945"
     CDS             complement(4603..7281)
                     /locus_tag="VXC24_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0494015.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7530..7817
                     /locus_tag="VXC24_001946"
                     /pseudo
     CDS             7530..7817
                     /locus_tag="VXC24_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2579 a         1617 c         1090 g         2531 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catattcaat gagatgttgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
      361 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
      481 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc agaagactct
      601 aaataaggat ttactaagcc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt
      721 tttaataact ttgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaactcg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ctctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt ggaataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattgct agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aataaccgcc
     2161 acaattaaag catttacaat atttgatggt acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatacgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acatcataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggc ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
     2761 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
     2821 ccataactag ctggtatcac aggtacacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
     3301 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccttat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 cagtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat catcgtcaca ataagttgta ttttcaacca
     3661 agcgatgggc aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt
     3721 taaactcagt acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga
     3781 ttttatacga ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctatga
     3841 atgcagcttc gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc
     3901 ttttcccaag ctcaaattct tctttataat atttcgagat ttcccagcgt aggggattcg
     3961 aaataataac tccttcttta taacgttcta tactcgaaga aatatgatcc gttagattta
     4021 tatagataat ctcatcaaaa ttattaccta atgttatttt acctagatta attatttttt
     4081 cggtgatgta caccaactcc aaaggaacgt taataaacat ctctgtaaaa cgggtcatat
     4141 tatctctatt tttgagaaaa aaacttttct caatatcaat tggatttact ttatctccaa
     4201 tttttcttcc aaaagctatt ccccttccaa aaagaagaat atcgatatct tttttacttt
     4261 gcgcaattac ggcattgtgg tttagtattc gttttatgat cataaaattt cccttttaaa
     4321 ataaaaggaa cctacttaaa aacatcaaga aacttcttct gatgtgatta aataggttcc
     4381 tgctcacttg tattagtgat aacatccttt tatttcaatt tttaatggtg acatgaagct
     4441 taaataatta ataactctgt aaccattttc attttaagat atttcaatct atttgtcaag
     4501 tacttgtaga aattttttta ttttgtgtga ttcgaatgtg ataatggcaa cagtctcact
     4561 aaagaaatga aaatcataca tagaaatttt taaaaatttt ctctatcgta aacctgccac
     4621 tagttcagaa actatactag ctgattccaa acgtaatatg gtcatctcat ctaccttccc
     4681 taataatggc attgcatcat accaaacaat agtcttattc accaaaagaa taggcgttac
     4741 tatttttgat tgagtaaaag acactttaat tttctggctc ttcaactggt ctagccatgc
     4801 tttatttgca accgtctctg gtatacatat ctcaatttga ctaatcctaa attcttttag
     4861 aaaattcatc agttttgtct ggtgcacata aggtaaaata agcagacatt cctgtctttc
     4921 ccctgctaag tcctctatca acaccttctc atatctacta tcaacataaa cgaattgttt
     4981 ctcctcaccc tcaatggcac gataatccat ctttcgataa gctacttgtc gtttctgaaa
     5041 catcttttct aaataaggaa catgaatatc cacataatcg aaaatacgca ccaaagactt
     5101 atccttgtag tttctatgaa tccgacctgc atactgaatt aaattatttt tccaagaaaa
     5161 gggtgctgcc aagataagcg tgtccaactg aggtaagtca aaaccttcgc caatgtattt
     5221 tccagtagac aacaaaacaa accctttatc taactgttct aacgtctcca gtaaactcgt
     5281 tctttctcgg actttggttt ttccgctaat aatgtaacag tcatcaacct ctttctcttt
     5341 caataacttt tcaaagacat ctatctgttg aattcgatta actaaaacca agatattccg
     5401 tccttctgcc acttgggcta gaatatcctt gagaatcaac tgattcctcg ctgagtctgt
     5461 agcaatccaa tcactgagct gtataaaatt acttgctttg gtcttttcaa tctccaaatg
     5521 accaaaagaa gtgaatctta attgcaattg ccgtttaaaa tccgtttccc tcttatcagc
     5581 agtatggagt atctcaccaa ttctctgaaa aacaataggc tcatgaccat tcttacgctc
     5641 aggcgtagcc gtcaaaccgt aaagatactt ccctctaaac tgagcaacaa ctttttcaaa
     5701 catcaaggca gagacatgat gacactcatc cacaatcatc atctcatact catccaaaag
     5761 actttgacta ttttccaact taaatagaga ttgaatcata acgacatcaa ccagtttact
     5821 cagccatttc ttagtcccac cgtactgtcc aacatagccg attacctttt cacgacctga
     5881 tgccgtataa cggatagcct cctcctcttc gaaagtcaaa aagcagttta agcgatctag
     5941 ccattggtct aagagttgct tattatggac tagaataatt gtttttgttt tccgttcaga
     6001 gataagagca gcacctaaaa cggtcttccc aaaaccagtc tccgcatgaa gtaaaccatt
     6061 ttctttagaa gtcatatctg acagggctaa ctcttgctca aaagtgagtt ctcccttaaa
     6121 ttccacgcta atagaccttt gtacctttct cctatcttcc acaactacct gcttaaattt
     6181 atcttgcaat ggatacagca aacctcttgg caaccataaa taatgatcgg attctccaaa
     6241 taaatacatt ctctcaggaa tttgataggt tggctgtcgc atagcctgct ttaaataaaa
     6301 ttcgggatta gaaaatgaag ccatattttt caagaaaaac agtgtcttgg gtgtcacaga
     6361 cgatttttca agttggatca tattggataa gacgatcttc aaccccttgt ccaattcttg
     6421 cttgcctaac tcttcttgga ttaacagtgc cactttagca gttgaaaccc tctgaatttc
     6481 ttgtagatac ctccattggt cttcataagg ctgaaactgt tcatccacaa agaccgttcg
     6541 cccttgatgg taagcttctc cttgaaaagg caaggcaatc aaatttccaa atcccccctt
     6601 aggaaggaca tcctgatttg gaaacatgcg atcaaaagaa tcaaaggaca gttgcatact
     6661 ttcctgcatt gccagttcta tcagtttctt tccaaacaag cgagcctctc gactcggaat
     6721 cgcttcctca aagaagaacc aaatatggag tccgtgaccc gaacgagaaa tctctaaatg
     6781 ggcttccatc tggcgttccc tggctattct tcgaatggtt aaaccagctt ctttccaatc
     6841 tccttcatca aaatccagta ccaaaaaatg acagctatca tctaagtgca taggaaagat
     6901 accgatagct gtctccccac gaaaatgaga tttcaaaacg gagttcgtca atgtctggaa
     6961 actccgtttt tcaggtggca actgcttcca accataatca taggaaggaa aatactgaat
     7021 tttcccttgt tcattgataa aattcttagc ataaacatca taacgtccag caaacacgga
     7081 ggtaaacaat tgtaattttt cttgcgtcgt caagtgacta ctttgaagtt ggaacatctc
     7141 ctcgaaccga gagcgttcca taacaaactg actcttgtct ttaagacgtt tacacaagaa
     7201 aaactcacta tccccatcaa aagaagaaaa gacatcaagc acttctacca caattccatc
     7261 caaagacaca aaaacagcca taagagtcac ctccttgatt cctataggct gattataaca
     7321 agaatagctg aaattgtaca cgaaaataaa atccgaatag cactcatttt gtatgcgact
     7381 aatagtccat ctcgctccgg aatgtacgag gtaaatagag tttaaacgag cagtctataa
     7441 aattcaaaaa acgcatatta ccaaggttgt tttgaactac accccaaaag ttagacagaa
     7501 aaaatctaac tttttggggt gtttttatta tgaaattaac ttatgatgat aaagttcaga
     7561 tctatgaact tagaaaacaa ggatatatct tagagaagct ttcaaataaa tttgggataa
     7621 ataattctaa tcttaggtac atgattaaat tgattgatcg ttacggaata gagttcgtca
     7681 aaaaaggaaa aaatcgttac tattctcctg atttaaaaca agaaatgatt cataaagtct
     7741 gacatgaagg ctggactaaa gatagagttt ctcttgaata cggtctccca agtcgtacga
     7801 tacttcttaa ctggcta
//
LOCUS       DAVLBN010000080         7768 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLBN010000080 DAVLBN010000000
VERSION     DAVLBN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.080"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(835..2055)
                     /gene="divIB"
                     /locus_tag="VXC24_001947"
     CDS             complement(835..2055)
                     /gene="divIB"
                     /locus_tag="VXC24_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0494016.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            complement(2065..3123)
                     /locus_tag="VXC24_001948"
     CDS             complement(2065..3123)
                     /locus_tag="VXC24_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0494017.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3127..4479)
                     /locus_tag="VXC24_001949"
     CDS             complement(3127..4479)
                     /locus_tag="VXC24_001949"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0494018.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(4583..5224)
                     /locus_tag="VXC24_001950"
     CDS             complement(4583..5224)
                     /locus_tag="VXC24_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494019.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(5226..7247)
                     /locus_tag="VXC24_001951"
     CDS             complement(5226..7247)
                     /locus_tag="VXC24_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0494020.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(7318..7617)
                     /locus_tag="VXC24_001952"
                     /pseudo
     CDS             complement(7318..7617)
                     /locus_tag="VXC24_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
BASE COUNT         2327 a         1693 c         1325 g         2423 t
ORIGIN      
        1 taaaaatatt tatctttttt cgtgatttca tagaatctat aagtcccatt ttactaagaa
       61 caatataaaa tcttaaataa tatttcttcc ctactaacac taataagtcc gatatggtaa
      121 attcttgacc tattagttgc tctaaccatt tttttcctgt ttcccaacta atacatgttt
      181 cttactggat ggtatatata gatgatactg tccctcataa ggagtaggta atatcttaat
      241 cttatcaaca attctcataa caaacctaac ctttaataaa taaaagaggg gctaagtaaa
      301 acatactcta gtccctcagt ccgcaatcaa taaaataatg actaattcta ttaatctctt
      361 gctgcaagac taatacggaa aattcaaatg actgtctaaa ttgaaaaagc ttgatattag
      421 taagtgaaca aacttcaaca accagcaaga gcaaggattg ctaaaccaaa tccgatacct
      481 gttgcaagtc cagctgaaaa atcactaact ggtactgaaa tttcttcaat ttcctcaaat
      541 aaaaagttat cttgcatgat tatcactccc tatcttttta acaacaggct actccaatta
      601 agagaactac cccagttcca agtaaaactc ccccccaaaa ttcaccatct gtaggggcta
      661 cgatttcttc aatttcttca aataagaata cttcatctga catatgtgtt accttcttca
      721 taaaaaattt ttttgtaatc gattacattg caaatgtaac ataaagaaaa acagatgtca
      781 aatattaaac gtaaaaacat ggcaactaaa gagctatagg agaaaaggta aaacctagcg
      841 acgcgatgag cgctgggtcg tttggtttcg attgctctct tcctcttgtt ttttctgttc
      901 ttcttctaaa cgtttacgtt cctcttcctg ccttttctca gcttcttcgg cctctttttt
      961 agctttttct tctgcttcca taatcaattt atccgctaca gtgtagctgt agactccagc
     1021 ttccatgtca atcacactcg gttctgacaa ttgtggctta atcttactgt aatatggcag
     1081 tttcttactc atttcagata gaggaaccaa gacttcgtcc gaatcattca tggtcaatcg
     1141 aattaaatcg gatgtcacct tgcttggggc taattccacc ttttggatag ccgccttgag
     1201 ttctgggcta atttgagcaa gttctgagac aaaaaccttg atttgttcac tatcattaaa
     1261 gagaactgat aaataagttt ctggtaaact gttcagactc acagaactag tctcaagctg
     1321 accactggaa agaataggat aatgattttc accagaaata tagtaggcca caatatcata
     1381 ttccttgacc ttaatagtga acttagttgg aaattgatag acaagttgag ctgattcaac
     1441 ccaatagtta gacttaatct gcttttcata ttttgccttg tctagcagaa ggttaatcgt
     1501 ataatccgaa tcctgaatgc ctgaagcctg tcgaatatca tcagctgtag tttgcaccgt
     1561 tccctcaaca cgaatatctt tcatggtcgc ataaggactg agcaagtagg cagagacaat
     1621 caataaaagc agacttggaa ataaaatcgt gaaggctcgc aagatatgga taccaggaat
     1681 ctttgctttg gctggttttt cctttgtagc ctttttagca agctttttat cctgttcctc
     1741 cttctcttta gactctggtt cttctttctc ttctttctct ttgtcagcct ctgaggatgc
     1801 tactttttct tcagactctt ccttagctga ttctgaatct ttctggtctg tttcactctc
     1861 ctggtcctgt ttatcctctg acttctcaga ttcttctccc attcgagctt gtctttcctt
     1921 ttccttctcc tcagctagag ccgcctcttc ttcagccttc ttttttagat attcttggtt
     1981 tcgtttctgc cattctgata actctttcaa ttcttcgagg gtttctttgt cctcattttt
     2041 cttatctttt gacatttact ttccttatga taaatctttt ttcaacaatt gataaaaatc
     2101 tgctagagat ttcaattcct tagaagcttt catcttagct tggtaatctt ccttgtgact
     2161 tagtaagtga gaaagcttct cttccaaact atccaaggtc aaatcgcttt cttgaaggtc
     2221 ttctgcatag cctttcttaa caaagtaagc tgcattttca atctggtcac cacgactagc
     2281 ttcacgacca agcggcacaa tgacatgcaa ttttgctatc gccaagagct caaaaatcgt
     2341 attggcacca ccacgtgtca caacaatatc agccaattcc atcaagggtt gatagagatc
     2401 ggtcacatag tcaacacgaa aaagattttg gctcaactca ttcaggctag aatctccagt
     2461 tagattgata atattgtagc gctctgttag ttctttttta tggtctgtca ccaattggtt
     2521 aaagacacga gcacctgcag aaccgccaac aaacaataca gtcggcaatt tatgattaaa
     2581 gtggctttga atatccacca attcatctgg ttctggattt ttttgatctg aaaccttggt
     2641 cactgctccc acatgctcaa ccttagccaa actcgaagct tgttcaaagg ttgaatacat
     2701 cttagtcgca aatttatagg cgattttatt ggccaagccc atagacaggt cagattcgtg
     2761 aataaagaca ggcactcctg acacacgcgc agcgataaca ggcggtactg agacaaagcc
     2821 cccctttgaa aaaagggtct gtggacgaag tcgcaacatg ataaagagcg attggacgat
     2881 tccccagcca actttgaaga cgtccagcat attttgccaa gagaaatagc gacgcaattt
     2941 cccagtcgca atggagtgga aagtgacatc caaacctgac ttaaggattt cttggtgttc
     3001 gataccacgc ttgtccccga tatagtggac ttcccaacca tcttcgatga acttgggcat
     3061 taacaaaaga ttgagggtaa cgtgtccaac cgtcccccca cctgtaaaga caattttttt
     3121 catattttat tcttttaact ccgctactgt gtcgataaag aggtcgccac gtacttcaaa
     3181 gttagcatac atatcccagc tggcattggc aggactaaga agaaccacat ctccttgagt
     3241 cgcaagctca taggccttgc gggtcgcatc tgcaatatct gtcgcctcca cataagcgac
     3301 accagccttg tctgctgccc gtttgacacg ttctgcagat tgacccagga tgaccatctt
     3361 cttgagtcca gtaatatctg gcaccaattc gtcaaactca ttgccacggt ccaaaccacc
     3421 tgcaatcaag acgaccttgc tgttgtcaaa tcctgacaag gctttttgag tagccaagat
     3481 attagttgat ttactgtcgt tatagaattt aacacccttg atgtcatcca caaactggag
     3541 acggtgtttg acaccaccga aggctgaaag agtttccttg atggtttgat tgtccacacc
     3601 acgaagcttg gctacagcaa tagtcgcaag ggcattttcc acattgtggc tacctggaac
     3661 accgatttca ttcgctgcca tgactacttc accacggaag tagagttgac catcttccag
     3721 ataagctcca tcaacctttt caagtgttga aaatggtaca acagtggctt ctgtcttgga
     3781 agtcaagtct tttgccaagt cttgattaaa gttcaagaca aggaaatcag ctgctgtcat
     3841 cttgttctgg atattccact tggctgctac atattcctca aataatccat gataatcgat
     3901 atgagttggc ataaggttag taataaccgc aatctctgga tgaaattctt gaacacccat
     3961 gagttggaaa gaagaaagtt ccataacaag cgtgtccttg tccgacgcag tttgggccac
     4021 ttgactagct ggatagccga tattccctga taaaagacca tgttgcccag cagcagtcaa
     4081 aacttcccca atcatagtcg ttgtggttgt cttaccgttc gatcctgtga taccaataat
     4141 cggtgcttct gaaatcaaat aagccaattc cacctcagtc aagactggaa ttcccttggc
     4201 caaagccttt tcaatcatgg gattgttgta ggggatacct ggatttttca ccataagggc
     4261 aaactcttca tccaagagtt ccaaaggatg gccacctgta atgaccttga tcccttcttc
     4321 cagcaaactt tgggcagctg gattgtcctc gaatggtttc ccgtcattta ctgtcactat
     4381 ggcgcctagc ttatccaaca aacgagctgc agattcacca gacttggcca aacctaaaac
     4441 aagaactttc ttatttttaa attgatctat tactttcatg tctcgaactc catttctact
     4501 cctactattt taccattttt atggaaataa aaaagccaca aagtgtgttt gtgactcttt
     4561 cttctaactg aatcttacca tattatctat gtgataaatc ggtaactcga atgacctgat
     4621 ccacttgctc ccaaatcaga ggattgtggg tcgcaataat aatggtccga ttcggatttt
     4681 ttaaagattc taggatggaa agtaattcct cagagttttt ggggtctaag gaagcggttg
     4741 gttcatctgc aagaatcaaa ggcggatcct ttaaaattat cttcgctaat gcaacacgtt
     4801 gtgcttctcc tcctgataac tcaaatatag gttgcttcaa atccaaataa gagaggttta
     4861 cacggtttag agcttgtttc atcaaagaga ttttctcttt ttccttcaac tttttaccaa
     4921 ctaaacccag attgagattc tctttgacgg tttggctttc aattaagcca aaatcttgaa
     4981 ataagtatcc caagtaatct ctaaagaaaa cagaaggctt gatgtcctta agagaagtgc
     5041 catcatagat gatttgccct ttgtcatatg gctctaatcg tccaatcata ttcaagagtg
     5101 ttgtcttacc acagccactt gtaccgatta aggcataaat tttcccacct tcaaaatgaa
     5161 gatttgtatc tgaaaatagc tgacggcttc caaatttttt agatatattc tttagttcaa
     5221 tcatcctatt ttcctttcat aattgtcata gaaacacgag attctttctg cgcttgacgg
     5281 taaagcgtca gaactgcact agctagaaag actaataaag tgagcaagcc aatcaccaag
     5341 tctcgactgc ttaaaataaa gagactagca ccaaatacaa aactggcaaa ttgactaacc
     5401 atatactgag catgtgtttc aaaaaatcgt aaacctgaaa ttcgtttaat caaaatatct
     5461 cggcggaatt gctcgaaata tagaagattg acagaataaa atagtaacaa ggaactagct
     5521 atccccacaa tagctcctaa gattaaagtt gctgtttcag tttgaacttc attataacga
     5581 gttagataaa cacttcttcc ttctttaaga taggatactt gctcataaat tccagctttc
     5641 ttcaagagtt ctagcccact ctcatatcct ttgataaaga gttgttttcc agcattgata
     5701 gaccaactag ataaggatat aaaactatca cctgtagaag tcggcgtgaa tacaactaaa
     5761 atcggatcaa tcaaatactg agtggatacg ggattctcac cgttattata aacaaaccgc
     5821 ttttctccca ttgaaagata actaacgtgc gctttcatct cataatccaa aggagcactt
     5881 gcctcctcac cagattttcc ataataactc aatctttctt caaaaacttt cttaagttct
     5941 gcttctcgag agcgcaaatg ttctgggagc aagaggataa actcaccttt ttggagatgg
     6001 gctaacttct gtttggtctc agcatctacc acgacctttt ccttgtccaa ataactggga
     6061 ctaacataga gcgtattagc atctggacta taggtatcca gtgtctctcc ctgttcattt
     6121 tttccttgtg gattggcaaa atggagcaga ttatccttta cataaagagc ttgttcttct
     6181 tcgattgctt ccttggcaaa ggcataccac ttgctctgat tttctgtatc ttttcctcta
     6241 tcacctaagc caaaagaaat ttgataatag tctgctctat cctgccatgc ttgttttgaa
     6301 atttcaagtt ctttcaatcg ttggtaagac gtcaaacctg tcttaacagc gtatcctact
     6361 gtaaagacag caaccaactg acacaatagg gttaaaatca tcaggcgttt aaggggtaat
     6421 ctccccttaa taacgggaac taatgctttg taattcaaac tcattagata aagaagcatt
     6481 agtaaaattg aaatcgccaa taaaaacaac agatagaaac taatcccaaa accataggtg
     6541 gctaacaaga taggataaaa caaaccttga ctaaaaagaa cgactccccc acctaggaag
     6601 gaaaggaggg ctgatagaag gagccatttg atatcagtag ataaagaatg ccccatgatg
     6661 gataagagag tctgaccaga aaagagtttt atacctgctg ctctcatttc cttaatccga
     6721 gtgataatca ctaaagcaaa gaaagataaa ccaaatattg ctaaactaat taaaataagg
     6781 ggatttagta atattcgaaa agcaagaaaa tagggcggta tctttcggtc agcacttgct
     6841 ttataaccca aatctcctaa tttatcggca agcttttctt tcgtcaagga gcctgacaaa
     6901 aggagataac tatttagcgg atcactacgt tcacgacttt cttggctagc ttcttggaat
     6961 tcttttggta aagttccctg accataagtt gcataagtaa agtgagtcgt cccatcctta
     7021 ctcggctcta caattcttct agctattaaa ctctgttctg agtttgcaaa attctccaat
     7081 tcctgttcaa atacctcacg cgtcggttcc tgagtatctt ttttgacacg aagtaaagaa
     7141 acggaatcat agcttgcata taaatattgt ggcgcacgta agacaataat ccaagcaagg
     7201 aagaagctga gaaaaaaagt tgataataat atgaatagtt tcttcatagt agactccttg
     7261 taaacaaaat tccccctgta atttcttaca aggggaacga tttaaatcaa tgaacgatta
     7321 gtcataatca cagtaaaatg ctacttgttc tccccattta gtccaaatcc atgcatagga
     7381 ggtttttcca gcaggagctt ctcctttatc agaatgacca tcccatctgc tcacgatgga
     7441 tgaataatga tattttttac catgatagta atttgaaaaa gcctaaccac ctcctgaacc
     7501 ttctccatat gtccatactc ctccatctgg atattgtaca gcagctgatg cagctcccaa
     7561 taatgtaaaa tttgaaataa gagctagagc aagtaatcta tgttttttcg ttttcatttt
     7621 attttttctt tcaaaaaaat cacaccttga gcaacaatgc aacaaaataa atcctcctct
     7681 ctcttttgtt gaaatcgctt tcttatgtga taagaataac atttttatta tttgttgtca
     7741 aggaaaaaat cgaatttttt agatgttt
//
LOCUS       DAVLBN010000081         7741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLBN010000081 DAVLBN010000000
VERSION     DAVLBN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.081"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..459
                     /locus_tag="VXC24_001953"
     CDS             <1..459
                     /locus_tag="VXC24_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0494021.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(494..916)
                     /gene="nusB"
                     /locus_tag="VXC24_001954"
     CDS             complement(494..916)
                     /gene="nusB"
                     /locus_tag="VXC24_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0494022.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(909..1298)
                     /locus_tag="VXC24_001955"
     CDS             complement(909..1298)
                     /locus_tag="VXC24_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0494023.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(1320..1880)
                     /gene="efp"
                     /locus_tag="VXC24_001956"
     CDS             complement(1320..1880)
                     /gene="efp"
                     /locus_tag="VXC24_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0494024.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(2009..3451)
                     /gene="gatB"
                     /locus_tag="VXC24_001957"
     CDS             complement(2009..3451)
                     /gene="gatB"
                     /locus_tag="VXC24_001957"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0494025.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3451..4917)
                     /gene="gatA"
                     /locus_tag="VXC24_001958"
     CDS             complement(3451..4917)
                     /gene="gatA"
                     /locus_tag="VXC24_001958"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0494026.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4917..5219)
                     /gene="gatC"
                     /locus_tag="VXC24_001959"
     CDS             complement(4917..5219)
                     /gene="gatC"
                     /locus_tag="VXC24_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0494027.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5432..6976
                     /locus_tag="VXC24_001960"
     CDS             5432..6976
                     /locus_tag="VXC24_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0494028.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            7231..7428
                     /locus_tag="VXC24_001961"
     CDS             7231..7428
                     /locus_tag="VXC24_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0494029.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            7539..7715
                     /locus_tag="VXC24_001962"
     CDS             7539..7715
                     /locus_tag="VXC24_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0494030.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2175 a         1531 c         1762 g         2273 t
ORIGIN      
        1 cgttactgga aactcatcca acaggatagt cgtaaattga gcgataaacg tttttatcgc
       61 cctacttttc gcatgcactt aacaaataaa gaaattcttg acaagatttt aagctattca
      121 gaagacttga aacaccacta tcagatctat caactcttac tttttcactt tcagaataag
      181 gaaccggaga aatttttcgg actcattgag gacaatctga agcaggttca tcctattttt
      241 cagactgtct ttaaaacctt cctcaaagat aaagaaaaga ttgtcaacgc ccttcaacta
      301 cactattcta atgccaaact ggaagcgacc aataatctca tcaaacttat caagcgcaat
      361 gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga tttttatcgc tttgaacatc
      421 aaaaaagaaa ggacgaaatt tgtcctttct cgagcttagc ttttcttcaa cccactacag
      481 ttgacaaaga gccttattgt tcttctgtta caaactggct gagcagtcca ttgataaaac
      541 gggcagattt ttgatcggag aagtcctttg caagctcgat agcttcatta acagcaacca
      601 gctgaggagt gtcaaatgaa gtgatttcaa agactcccaa gcgaaggagg tttctctcca
      661 cgagcgttaa gcgttcaatg gtccaacctg cttttaaatg ctgagtgatt tgcttatcta
      721 gttcttcctt tttagcttga acaccagaaa cgaggtctat caaaaaggct ggaagttgta
      781 catccgtata ttcacgatca tgagtatagg cgaaacgaca agcagtttcg acatccgtac
      841 cgaactcaag gctcatgaga gcttgaaaag cgcatttacg gagttggcgt ctagattcta
      901 atagtggact agtcattgag gaagtcctcg tcaaatagat ctttcaattc tggttttggt
      961 gttttatctg ggacgatacc tgcaacgtga atattgatag cagcgagttc tacatcagcc
     1021 atattacgga cggcatcttt gacagctttc tggatagcaa ccgctacctt aggaactttt
     1081 actccgtact caaggtagag atagatatct gctgtgagtt cttcgtccac gtttttaaga
     1141 taaatgccac ggccgagtga aagttttgaa agggtatcag acactgatct gtttgaaaaa
     1201 gagtgaacac cctctacctt tgcagtagcg atagcaatga ttttttcaag tacacgtggg
     1261 gcgataacga tttcgccaag ttgttcttca attcccatag aatgacctct ttctagagat
     1321 taggcacgag aaacgtaagt tccttctgca gtgttgataa cgagtttttg tcctgcttcg
     1381 atgaagtctg gaacgtttac gacaagtcca gtttccatcg ttgctggttt accagaacct
     1441 gtaacagtag cacctttgat agatggttga gtttcagcaa ctgtcaactc aacagtagta
     1501 ggaacggtga caccgatcac ttcagttccg tagaattgga ttttcacatc agagttttca
     1561 aggatgtaaa gcaattcgtt ttcaacattg actacaggga tttcgtattg gtcgtaagtt
     1621 tctgtattca tgaagtatgc tgtgtcatcc attttgtaca agtattgagc tgggacagtc
     1681 tcgataatag cttgttcaaa tttttcctct ggacggtagc ttgtgtcaaa tgtagaacca
     1741 gtacggacat cacgcaattt catacgcatg atcgtgtttc ctttacctgg tttgtggtga
     1801 ctagcttcca aaacgcgaat caatttgccg tcagctgttt caaaggtcat accagctttt
     1861 aatttacttg cttcaatcat gtttttacct ctttaataaa tattattact cttcatttta
     1921 ccataaaata ctctggaaat aaagccaaaa tagttattgg gagttggtag agaagaaaaa
     1981 accaacctta gggctggttt tgttctgtct agttttcttt caacttcgcc aattcctgtg
     2041 caagtagttt aagggcaact tgtgggttgg cttggccttt ggttgccttc ataaggaatc
     2101 ctgtaaaggc cttgtcggcg ttacgtttgc ctgacttgaa gtcggcaaca gcagcttcgt
     2161 tatcggcaaa gacttggtgg atgattggga tcaagatagc tggatctgaa atttgaacca
     2221 tacctgcttt ttccacgtat tcacgcgcgc caccgccatt tttagctaga tggacaaaga
     2281 ctttcttggc aatcttagat gaaatagtac cgtcttcgat gatggtaatc atttcaacca
     2341 agttttctgg tgtcaattcg atttgttcca gtgttttacc ttcagcattc aagaactgag
     2401 cgacttcccc ttggagccag ttagagactt gtttggcatc accacctagg gcaacagctt
     2461 tttcaaagaa gtcagaagtg actttattag cagtcaactg actagcatcg tagtctgata
     2521 aaccaaggtc agatacataa cgcgcacgac gttcttttgg aaactctggc aactcagtcc
     2581 gcatttcctc aatccactcg tcagaaattt caaagagggg taggtctggt tctgggaagt
     2641 agcggtagtc agcagcccct tccttgacac gcatgaggat ggttgttttg ttagcttcat
     2701 cgtaacggcg tgtttcttgg cggatttgac cacctgagcg aagaatttca gcctggcgtt
     2761 ggacttcgta ttcaagacct ttacgaacgt ttgagaagga gttgaggttc ttcaattcag
     2821 tcttggtacc gaatttttct tgaccataag gacgaaggga gatgttggca tccacacgca
     2881 tagaaccttc ttccatctta acgtcagaaa tgccagcgta ctggataact tccttgaggg
     2941 ctgtcagata agcataggct tcttcaggag aacgcatatc tgcctcagat acaatctcaa
     3001 tcaagggaac cccttggcgg ttgaggtcaa cataagagta gccatctgta ccatgggtgt
     3061 ttttaccagc gtcttcctct aagtgggcac gttcgatacc gattttcttg gtcgtaccgt
     3121 cttctagttt gacttcaatc cagccattat atccgattgg ttcatcaaat tgagaaattt
     3181 ggtaggcttt ggggttatca ggatagaagt agttcttgcg gtcaaagtgc atctttttgt
     3241 ggatgtccat gttgagggca agagcagcct tgataccggc atcaacaacc cctttattga
     3301 gaactggtag aactcctggg aaagaccagt caattacgtt agtgttggca ttttggtcat
     3361 ttccgaagtg ggcagaagta ggtgagaaga tttttgaatt ggtgttgagc tctacgtgga
     3421 cttcaagtcc gatgactgtt tcaaagttca ttagttgtca cctccaaaaa tcacgggttg
     3481 ttgtttgtgg tagtctgttg ttgcttcaaa agcagcagca gcttggtaaa tggtttcctc
     3541 agagtacttg ggaccaatca attggagtcc gacaggtaga ccttgagaga atccagcagg
     3601 aatcgaaatt ccaggcagtc ctgccaagtt tacaggtatg gtcaagaggt cggctaagta
     3661 catggcaact gggtcatggt tgagagaatc caagtcatag gcaacacttg gagcagttgg
     3721 acccaaaatc aaatcgtaat ccgcgaagac tttttcgaaa tcttgaatga taagtgtacg
     3781 gacctgtcca gccttcttgt agtaggcatc gtagtaacct gatgaaagac tgaaagtacc
     3841 cagcatgata cgacgtttta cctcttcacc aaaaccttgg cttcggctgt ttacatagat
     3901 ttcatcaagg ttggttgcat cttctgcgcg atagccgtaa cggataccgt caaagcgttg
     3961 caagtttgat gaagcttctg atgaagcgat gatgtagtat acggcaactc cgtatttaga
     4021 gtgaggaagg ctgacttctt cgacaatagc accaagtttt tcaaagtgtt tagcggcact
     4081 tagaatggtt tccttaacct ctgggttaat tccttcaccg aggtattcct taggcaaagc
     4141 gattttcata cccttgatgt cttggccgat ttttgaagta aagtcggcga tgcggacaga
     4201 agcagaagta gagtctttag catcttcgct ggcaatagcg ttgagcaaga gggcattttc
     4261 cttaacagta ggagcaaaag gtccaatctg gtctaatgag ctgccaaagg caatgagacc
     4321 gaaacgtgaa actgttccgt aggttggttt gagaccaacg attccgttga aggcagcagg
     4381 ttggcggatg gaaccaccag tatcagaacc aagtgacaag cgaacttgtc ctgaggctac
     4441 agctgcggca gaaccacttg atgacccacc aggaaccttg ctgtggtccc aagcgttttt
     4501 agttgctccg tagtgtgaag tttcacctga accacccata gcaaattcgt ccatgttggt
     4561 ctttccaacg acaatcatgc ccttggtttt tgcattggca acagctgtcg catcaaagat
     4621 tggctcatag ttgtagagca tttttgaggc agcagttgtg agaataccgt ctgtagagat
     4681 gttatcctta acagcaagtg gaattcctga aaggacattg tcagtatcaa ttccagcttc
     4741 atcaatggct ttagcttgaa caagagcttg ctcctcagcg atggtgacaa atgaattgag
     4801 ggcttcctca cgagacttga tattttcaag tgttgcttgg gtcaattctg ttgcagaaat
     4861 ttccttagag acaaggagat tgtgcaactc ttcaatagtt ttatcgttaa aagtcattag
     4921 gcatctcctc catcgtctag gatagctggc accttgatat agtagttgtc tttttcaggt
     4981 acgtttttaa acaagcgatc acggtctgtt ccttcttcgg ccacatcagg gcggagtaca
     5041 gtcttgcggt cagccatagt cgtagtaggt gcgacaccag ttgtgtcaac ttcgcccagc
     5101 aattcaacca tgtcaacaat cttagacaag gtggtcgcaa aggcagcagt ttcttcttca
     5161 gagaatctta attttgaaag attggcaacg tgtgttacct cttcttgcgt aattttcatc
     5221 ttgcatcctt tcgtgaaatg atgattttta gtctgttcta ttttaccata ttttcctata
     5281 aataagggag ggggaagtga aaagaaatag aaattgaaaa aaatgctaaa atccgatata
     5341 atggagtgtt gaaaggaatg gtaaaatcca atgtaaaaat cattctcagc tattgaaaca
     5401 agaaaaatag agaatcaaag aaagagaact tatgaatatt caagaagaaa ttaagaaacg
     5461 tcgtaccttt gccattatct cccacccgga cgcggggaaa acaaccatca ctgagcagtt
     5521 actctacttt gggggtgaga ttcgtgaggc tggtacggta aaagggaaga aaacagggac
     5581 ttttgctaaa tctgactgga tggatatcga gaagcaacgt gggatttctg ttacttcatc
     5641 tgttatgcaa tttgactacg acggcaagcg cgtgaatatc ttagacacgc cagggcacga
     5701 ggacttctca gaagatacct atcgtacctt gatggcggtg gatgctgcgg tcatggtcgt
     5761 ggactctgcc aaggggatcg aggctcaaac caagaaattg tttgaggttg tgaaacatcg
     5821 tggcattcca gtctttacct ttatgaacaa gctggaccgt gacggtcgtg agcctttgga
     5881 tctcttgcaa gaattggaag aaatcttggg cattgctagc taccctatga actggcctat
     5941 cgggatgggg aaagcctttg agggcttgta tgacctctat aaccaacgtt tagagcttta
     6001 taaaggggat gagcgttttg ccagtctaga agacggggac aaactctttg gtagcaatcc
     6061 tttctacgag caagtcaagg atgacattga gcttttaaat gaagctggga atgagttttc
     6121 agaggaagct attctggctg gagaattgac gcctgtcttt ttcggttcag ccctgacaaa
     6181 ctttggtgtg cagaccttcc ttgaaatctt cctcaagttt gctccagaac cacatggtca
     6241 caagaaaaca gacggtgaaa ttgtggatcc ttatgacaag gatttctcag gctttgtctt
     6301 taaaatccaa gccaacatgg atcctcgtca ccgtgaccgt attgcctttg tccgtatcgt
     6361 atcaggcgaa tttgagcgcg gcatgagtgt caatctccct cgtactggta agggggctaa
     6421 actatctaat gttacccagt ttatggcgga gagtcgtgag aatgtgacca atgccgtggc
     6481 aggtgatatt atcggggttt acgataccgg tacttatcag gttggggata ccttgacggt
     6541 tggaaaaaac aagtttgaat ttgaaccact gccaaccttt actcctgaaa ttttcatgaa
     6601 agtttctgct aagaatgtta tgaagcaaaa atccttccac aaggggattg agcaattggt
     6661 gcaagaagga gccgttcagc tttataagaa ttaccaaaca ggtgagtaca tgctgggagc
     6721 tgttggtcaa ctccagtttg aagtctttaa acaccgtatg gaaggcgaat acaatgcgga
     6781 agtggtcatg agcccaatgg gtaaaaagac cgttcgttgg atcaagcctg aggacttgga
     6841 tgaacggatg tcgtcaagtc gcaatatctt agccaaagac cgttttgacc aaccagtctt
     6901 tctctttgaa aatgactttg ccctccgctg gtttgcggac aagtatccag acgtagagtt
     6961 agaggagaag atgtgactca gtaccaacaa ttggaactaa agttccaaat tgttggacgc
     7021 tagtcgctat ttggcgaact agctaactgc ctcactaact acgtttggca aatgaaatcg
     7081 atttgtaaaa ctccgtgtcg taatgtaaaa attgtaaacc gtaatgggac ttcatctaaa
     7141 atctccactg gtatggtttt acgaacgaat aggcgaaaat aatggttacg tagaaacata
     7201 tgatgggaat aaaaagaaat gagataaaaa gtgaaagaag agaaaaaagc gattgtctta
     7261 ggtgcagata atgcttatat ggataaagtt gaaacaacaa taaaatctct ttgtgttcat
     7321 cattataatc ttaagtttta tgtttttaat gatgaccttc cgcgagaatg gttccaattg
     7381 atggaaaaaa gactagagac tttgaatagt gagattgtga atgtttagat tgacagtaat
     7441 attctgaaag gttatcgtct cccctttgag ggactttcat atgcggcttt tttaggtatt
     7501 ttattccaaa gtatgtaagc gagtctcgtg tactgtattt ggattcagat attgttgtaa
     7561 gaaaatcgat agatgagctg tgggatttgg acttgacggc tataccctta gctgcagtta
     7621 gagatgattt ttatacacat aattttaatt ctggtgttct gttaatcaac gatggcatgt
     7681 ggagagcaga aaatgtcacg caagacctga tttaagacac aaataaaaaa tcttccaatt
     7741 c
//
LOCUS       DAVLBN010000082         7648 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLBN010000082 DAVLBN010000000
VERSION     DAVLBN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.082"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(109..1275)
                     /gene="recA"
                     /locus_tag="VXC24_001963"
     CDS             complement(109..1275)
                     /gene="recA"
                     /locus_tag="VXC24_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0494031.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1330..2586)
                     /locus_tag="VXC24_001964"
     CDS             complement(1330..2586)
                     /locus_tag="VXC24_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0494032.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2671..3687)
                     /locus_tag="VXC24_001965"
     CDS             complement(2671..3687)
                     /locus_tag="VXC24_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0494033.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3695..4213)
                     /locus_tag="VXC24_001966"
     CDS             complement(3695..4213)
                     /locus_tag="VXC24_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0494034.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4203..4646)
                     /gene="tsaE"
                     /locus_tag="VXC24_001967"
     CDS             complement(4203..4646)
                     /gene="tsaE"
                     /locus_tag="VXC24_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0494035.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4732..5352)
                     /locus_tag="VXC24_001968"
     CDS             complement(4732..5352)
                     /locus_tag="VXC24_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494036.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5735..6598)
                     /locus_tag="VXC24_001969"
     CDS             complement(5735..6598)
                     /locus_tag="VXC24_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0494037.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            7063..7287
                     /gene="pneA1"
                     /locus_tag="VXC24_001970"
     CDS             7063..7287
                     /gene="pneA1"
                     /locus_tag="VXC24_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEV0494038.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            7294..7482
                     /gene="pneA2"
                     /locus_tag="VXC24_001971"
     CDS             7294..7482
                     /gene="pneA2"
                     /locus_tag="VXC24_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEV0494039.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
BASE COUNT         2335 a         1609 c         1271 g         2433 t
ORIGIN      
        1 ctaataaagt tgttcatatc ttatttcaag ctactatata taatatataa tctaaaaact
       61 tgaatcaaaa atcgaaaaag tagcggattt ctccactgct ttaacagctt attcttcaat
      121 ttcgatttca agttcatcgc ctaagtcaag cggaacttct tcattcactg cttcttcttt
      181 ctttggctca tcttttttgt tttcagtatc ttgttctgaa acttcttctc catcaatcaa
      241 gccaaattta gaacggactt gcttatcaat ttcatcaaag atttctgggt gctctgccaa
      301 gtatttctta gcattctcag aaccttgccc aattttttca tctttgtaag aataccaagc
      361 ccctgctttt ttgataatat ccaaatcgct tgcaatcttc aaaagctcac cagtcttaga
      421 aattccttct ccgtacataa tttcaactac ggcttcctta aacggtggag ctaccttatt
      481 ttttacaacc ttaatcttag tttctttacc gacattggtt tctttttgat caccagttcc
      541 cttaatttgt gtattaccac gaacatccaa gcggactgaa gcatagaatt tcaaagcacg
      601 tccgcccggt gttgtttctg gatttccaaa catcactcca actttttcac gcaattggtt
      661 gataaaaatg gcaattgttt tggttttatt gatagaggcg ccaagtttac gcatggcctg
      721 gctcatcata cgagcctgca aaccaacatg gctatctccg atatctccat caatttccgc
      781 acgaggaaca agggcagcaa ctgagtcgac tacgacaaga tcaactgcac ctgagtcaat
      841 caattttccc gcaatctcaa gaccttgctc tcctgagtct ggttgagaca agagcaattc
      901 gtcaatattg acaccaaggg ccgcagcata agctggatca agggcatgtt ccgcatcgat
      961 aaaggcagca atcccacctt ctttttgcgc ttgtgcaact gcatgaaggg caaccgttgt
     1021 cttaccagat gactctgggc catagatttc gatgatacgt cccttaggat aaccacctga
     1081 gccaagggca atgtcaagag ctaaagaacc tgagctcatc acttgcacct tttgctccgc
     1141 acgttcaccc aaacgcatga ttgatccttt accaaagtct ttctcaatca atttaagagc
     1201 gtcattcaag gccttttcac gttctgcccc aaattttttt gaaatttctt ctaatttttt
     1261 tggttttttc gccattctat tctcctacat tctaatgatc ctcagaccta tctactatta
     1321 tatcaaaagt tagtcactta ataaagcctt gcgaactagg ttaaaggcat gcataaccgc
     1381 aatgtgacgt acatctgctc ggcttctgcc tccaatatta accttgataa cctcagttcc
     1441 ttgatcttgc gccaagccta tgaagactgt cccaactggg tgtccttcta ggctatctgg
     1501 tcctgccact ccagtcaaac taattccaaa atcagactgg gtcttgcttc gtgcctgctc
     1561 agccatcttc tgagctgtaa attcagacac cacaccatgt tcttccaaat tcttggcagg
     1621 aatatccaac atccttgatt tttcctccaa gctataggtc acaaaaccac cctcaaatat
     1681 acttgaaact ccagaaaaat tcgccacggt agcttggaaa agacctgccg tcaaactctc
     1741 tgcagccgcg atggttttcc cttgcctttt cagttcttct accacaatgc tggctaaact
     1801 agtttcttcc ccataaccat agcaaaagtc tcgtaaagaa attccttcga aagtctggca
     1861 gtccaagatt tgattttcca agatatccag cgcttgattc gcctcttctt gactgctagc
     1921 ctttgttgac agacgtagag tgacttctcc tgtcttggca taaggggcca aggtaggatc
     1981 gatctgatta tcaattaaat cagccaaaat cgtaaccaac tggctctcgc caatcccaaa
     2041 gaaacgaaga actcgggaat acagcttgct ccctgtcatc aacttgggta gaagttggtt
     2101 taagaccatg ggtttcaatt cacttggcgg acctggaagg acgacatagg tcactccgtc
     2161 tacttctaat tttcctccaa cagccagtcc tgtttcgttt ggcagtggaa tcgctccttc
     2221 tacaatttga gcttgtcttt cgttattcgg tgttcgggca tagtctggtc gcagggcaaa
     2281 aaagatatcc aacttctcct gagcctgagg atcaaagact aatgctttcc ctaaaaattt
     2341 agctagggtt tgtttggtta ggtcgtcctc agttggcccc aaaccgcctg tcaaaatcac
     2401 cagactgcta cgttgactgg caatctcaag caaagacaag agacgaactt cattgtctcc
     2461 tacagccgtc tgaaaatata catctacccc aatctcagct agtttttccg acaaaaactg
     2521 ggcattggtg ttgacaatct gtcctgtcaa aatctctgtt ccaacagcaa tgatttctgc
     2581 tttcatgttt cctcctacct atctattcgt atttttttga aaaaatcgca ggaattttcc
     2641 tacgattgat ttttttattt gtatcaaaag ttaattatct tcatcaccaa caggtgctct
     2701 gccaaataaa tcttcaaata aaaccgcatt ggtttcaagc tgagtaactt cttcttgtcc
     2761 caaagaacgt cggagtatat tttgcatttc caacatatgt gctctcgaaa caatctggta
     2821 agaaacacct tgaagtatct ctccttcacc ctgcaactgc tgagtttcaa tggttttaaa
     2881 tgaatcttta tagcctagca agttagggat actttttgca gacaaatcaa tattggtctg
     2941 catattgtca ctcaaagctt ttagaatctc ttgataatga ccaatgctat ttaaactgag
     3001 agctttttcc atgacttttt gaataacttc acgttgacgt ttttgacgac cataatcccc
     3061 ctcaggatct tggtaacgca ttcgtgcata gactagggct tcttctcccc caatatgttg
     3121 ctccccaaca ccgatagaaa tggtattaaa ttcttcttgg tcactgatag aaattgggaa
     3181 acctaggata ttattgactg taatacctcc tactgcatcc actaattttt gcaaccctct
     3241 catattgacc atcacatagc gatcaatatg gatattcatc attttttgaa tggtttctat
     3301 agcaagctct gctccaccat ctgcatatgc tgagttcagt ttcgcttcat gagcctgacc
     3361 attccctgat tcaatgcgcg tcagaatatc ccgctctaaa ctcatcattg ttgttttttt
     3421 cgttttagga ttcactgtca tcaagatcat gctatcactt ctaccgaccc aagtttcagt
     3481 tcgttcaaca tttccggtgt ccactcccat taacagaatg gttagaggtt cagtcgcttc
     3541 aataaccttg gtttcttcac cgattttttt ataggtttta gctaaggttt ctgtcccttg
     3601 ttgataaata gtataagcaa aaacacctac tcctactaca gttacagaaa gtaaagctag
     3661 caccattcca ataatttttt taaccatatt tctactaacc tatcagttta cccatcaagt
     3721 aaacatcgat aaatttccct tcttctatat atgccccacg ctcttggcta ccttcaatga
     3781 caaagccatg cttttgataa agatggactg ctgcttgatt acgagtttgg acagtcagtt
     3841 ggagacgacg cagaatgcca cttgcttgtg cccactctat cgcttcttct agcaacaaac
     3901 ttcccaagcc attattccaa tatctttttc caatcacaat gaagagatct ccaatatgac
     3961 ggactctctt acgctgatca gctgtaatat ttacaatacc agcaattttg ccatttaaga
     4021 atgcaagtaa ggttatctga ttgtccgaac tagcttgctt gttgaggaat atttccatct
     4081 cctcactagt caagagaata ccatctccgt ctaggctggt aaagtctgtc tccaaactca
     4141 cacgatttaa aaaggccact aattcagctg catctttggg ctctgcttcc ctaatgagca
     4201 attcatactc catattgaag ctcctctaac aatttctcag cacgcaaacc ctttgcctga
     4261 aaatttaaac ggcgtccatc tgcttctttt agaatttcca attctaaata agcatctggc
     4321 aaggcatctc ctaagagatt tccccactca ataacagtca cgccgccacc aaagataaac
     4381 tcatccaagt cgatagaatc agcatctcct tcaatacgat aaacatctag gtgataaagt
     4441 ggaagtcgac cttcatactc tctcacgata gtataggtgg gacttttaat catttgagaa
     4501 atctgtaatc cttttgcaag tcctttagta aaggtcgttt tacctgcacc cagttctcca
     4561 gttaagatta aaacatcatt ctttgctaat agatggccca aacgctcccc taaggcttgc
     4621 aactcttctt cattttttgt gtacatactc ttattatacc aaaaactttt cttttgtgtc
     4681 tattttccta ctaaacttat catcataaca tccataaaaa acaggctttc tctaaaagaa
     4741 aatgagcgta acaatgacca atacaagatc tcggaaaata tgaccataaa aggaaacttc
     4801 cttcttaacc gaatttggga caagataggc tgcaaaaaac aagcccagtc caatataaat
     4861 cagaagtgag acaatggtca ttggatttct taagaaaaga agtgttgcta aaatagtcac
     4921 caacactgtc ttttttctgt ccagcatagc aagaaaatcg cgcacgtatt ttttcaaggg
     4981 taaaaaaatc agcaaatcta gcccaaatag gaaaaagaag gatggcaata aaaagtcaac
     5041 taattcttgc tgcagcgtat ttttgatgaa caagttatct gacaaaacaa gaacagctcc
     5101 taacaaatta attaagagta acatactgta aaaaagcttc accgacttct tactggctag
     5161 gacactatgg acttcttgct tacgggtata aagataattt actccagcac agattcctga
     5221 aacgaaaacc atgcttccga tgaaaaaagc tgtactttgt ttaaaggaca agatgcattc
     5281 cttccatagg aaacagctac tcaaactgat ttgaattaaa gctaacaaaa ataagattct
     5341 cattgatttc atcttctctc tcccttccta ccaatcatta tactaggaga aaagagagaa
     5401 ctgtttctaa tcttctcaaa tgtctcttta agacgctaaa caaacactag agactaatac
     5461 tcaatgaaaa tcaaagatca aactaggtag ctagccacag gttgctcaaa acagtgtttt
     5521 gagattgcag atagagctga cgtgatttga agagattttc gaagaatata aatttgaaat
     5581 catgaaaatc cgtcaaacgg gtgattgttt tgtctcgcac ctcacggagc gagacggact
     5641 cagagtcaca taattataag gctgatagta ttaatctaac tatcagcctt acaggttatt
     5701 taacgtttca gaaaaactat aatgtcaaga ttaactaaac agtatctagt tccttcaaat
     5761 aattttctat cttcatcaac attaaaggat tgttataaat cttacataac tctcttgctt
     5821 ctatataata atttttgact tgttctctgt ctagaaattt ggctccagca tttcctacaa
     5881 gaataagtag aggagccaat tggtagcttg tctgtctttg tttacagagt tcaatcgttt
     5941 caagagcttc ttggatggct tcattatatt tttcctttga tactaggtag tgagcgtagt
     6001 tgtaacgaac tctgatgtag ccaaataaaa actcttgatg gtccaaattt tttgtctgat
     6061 acaactctat taaatgagag tagtttgcct catattcttg ttcacgaccc actaaggaat
     6121 agaaattaga tagagtattc aacgccttta aataaatcag agtatttgaa gagactttta
     6181 ataatatatt ttccaatgac gaaattgcct cacacttact gtcatattga tagaagtcaa
     6241 ttatagattt aatccattca aggtaagttc ggtcttctaa tgttagaaaa gtgcttcgtt
     6301 ctacctctat tttataaaga tattctaaat cgtcataatt tctgtcatct aataggcgag
     6361 cagatagatg tttgaaatta gagaggttag acttaacttc gatttgttca ttgaaaaagt
     6421 aatccaaagg gacttcaagt cgttgagaga gtttgaataa caagtctgcg gagggaataa
     6481 aatgacctct ttcaatttta ctaatctggc tttgttcaca aattccttct gcaagagttt
     6541 gttgggagag tctcaactct tttcttttca atctgaattt ctctgcgagt gtattcatta
     6601 aagataataa accttcctat ttgcttaatt tcattataaa gtttttagtt caaaatagca
     6661 agttaaagga ataaataatt ctttatggta ataaacaaaa aaaaaagtta aaaattacat
     6721 aaaaatactt gactaaataa aatatatctg ttagaataaa aacaaggaaa aagaaagggg
     6781 tttcattgca tgagaaaaaa acgtggaatt aaaaaattag ttacatttgc attgctaggt
     6841 gtttttatgt ttagtaatac aattccttac caacagttta ttcagaagaa taaacaattg
     6901 gagattcgag tgcaatcgca aaagaagtcc aatggtcttg atgttgggaa ggcggattaa
     6961 aacccgatat tttgcacgag aatgagagaa ttataattta tctgaaaaaa cgaaaaatat
     7021 agagcaactt atttaacttt ttataaggag gagttattac ttatgaccaa ctttaattca
     7081 aacgaaaaat tttgtggaaa aagtttaaaa tcattgtctg ctgatgaaat gagtttaatt
     7141 tatggtgcat ctgatggtgc agagccacgt tggacgccta ctcctattat tttgaaatca
     7201 gctgcagcta gctcgaaagt atgcattagt gcagctgttt ctggtattgg ggggctagtt
     7261 agctacaata atgattgttt ggggtaaatt aaaatgaaaa atgattttgt aatcggaaag
     7321 agtttgaaag aattatctct tgaagaaatg caattggttt atggtggcac agatggtgct
     7381 gaccctagat caacaattat atgttctgct acattaagtt ttattgcatc atatttgggg
     7441 tcagctcaga ctcgttgtgg caaagacaac aagaaaaaat aaaatattca attttaaaaa
     7501 taaaagttgc tctttatttt cctctctcgt aactaataat tttgagagag gttttttttt
     7561 aaaacaatag taagtcgtat aggtttgagg taagtaaatg aaatataaaa ttaaaaatgt
     7621 gcataaaaca ttgtttatta aggaaaga
//
LOCUS       DAVLBN010000083         7201 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLBN010000083 DAVLBN010000000
VERSION     DAVLBN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.083"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..177
                     /locus_tag="VXC24_001972"
     CDS             <1..177
                     /locus_tag="VXC24_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494040.1"
                     /translation="AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKESQPTPIQ"
     gene            387..3506
                     /gene="phtE"
                     /locus_tag="VXC24_001973"
     CDS             387..3506
                     /gene="phtE"
                     /locus_tag="VXC24_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0494041.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            3732..4292
                     /locus_tag="VXC24_001974"
                     /pseudo
     CDS             3732..4292
                     /locus_tag="VXC24_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            4397..4745
                     /locus_tag="VXC24_001975"
                     /pseudo
     CDS             4397..4745
                     /locus_tag="VXC24_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(5016..5237)
                     /locus_tag="VXC24_001976"
     CDS             complement(5016..5237)
                     /locus_tag="VXC24_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494042.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            5202..5831
                     /locus_tag="VXC24_001977"
     CDS             5202..5831
                     /locus_tag="VXC24_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494043.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VXC24_001978"
     CDS             complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VXC24_001978"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0494044.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         2569 a         1254 c         1374 g         2004 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttgttaaaa gaaagtcaac cgactcctat acagtagtaa
      181 aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct tttttagaaa
      241 aacgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact ggttaattaa
      301 atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg agaaaaaact
      361 tcatcattta ttgaaatgag ggatttatga aattcagtaa aaaatatata gcagctggat
      421 cagctgttat cgtatccttg agtctatgtg cctatgcact aaaccagcat cgttcgcagg
      481 aaaataagga caataatcgt gtctcttatg tagatggcag ccagtcaagt cagaaaagtg
      541 aaaacttgac accagaccag attagccaga aagaaggaat tcaggccgag caaattgtaa
      601 tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat tactataatg
      661 ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat ccaaactatc
      721 aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg
      781 gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga actaaagatg
      841 aaatcaatcg tcaaaaacaa gaacatgtca aagataatga gaaggttaac tctaatgttg
      901 ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt aatccagctg
      961 atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac tatcactaca
     1021 ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat ctggctggaa
     1081 aaaatatgca accgagtcag ttaagctatt cttcaacagc tagtgacaat aacacgcaat
     1141 ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc cagagtcttt
     1201 tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat ggcctggtct
     1261 ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg catggcgacc
     1321 attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt gccagaatgg
     1381 tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat gaagtagtgt
     1441 ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag gagctctctt
     1501 cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg gctacagctt
     1561 atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa attgggcaac
     1621 cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc aatccaggaa
     1681 cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt attatcgctg
     1741 aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc ttcaagaagg
     1801 acttgacaga agagcaaatt aaggctgcgc aaaaacattt aaaggaagtt aaaactagtc
     1861 ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat gccaaagaaa
     1921 tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa caatatggtg
     1981 tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat ccgcatggag
     2041 atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt cattctcaca
     2101 gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg aataaagttt
     2161 atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg tttaataatc
     2221 aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg
     2281 agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga aaagtattgg
     2341 agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac tttgaattag
     2401 atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa gattatccag
     2461 aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa atggccagtc
     2521 aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac cctcaatttg
     2581 cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat ggaaatgctt
     2641 atttagaaaa taactataaa gttggtgaaa tcaaattacc gattccgaaa ttaaaccaag
     2701 gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat gcttatttgg
     2761 acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat caaactgata
     2821 aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca aaacttgatg
     2881 aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt tctgaaactg
     2941 ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct gtacaagaaa
     3001 aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg tttaatatgg
     3061 acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat atggcagatt
     3121 ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat ggaaaagtat
     3181 ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct ttaccagagg
     3241 caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg ttgaatccag
     3301 aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct ccagcagtag
     3361 atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggc ttagatagtg
     3421 ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa gtgataaaaa
     3481 agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga atcaaaaatg
     3541 aagttctctc aaaagttaga aataaaactc tgactttggg agaatttcat tttattatta
     3601 atatataaaa tttcttgaca tacaacttaa aaagaggtgg aatatttact agttaattaa
     3661 ttggttaatt aatttctata atcatttaat aatgaagaca tcatataaat aattatagaa
     3721 atgaggtaat tatgaaattt aaaaagaaat atatagcagc tggatctgtt gttatccttt
     3781 ccttaagtct gtgtgtttat gctctgaacc aacatagcta acaggccaat acagataaaa
     3841 atcgtgtttc atatgtaaac agtaataaag acactaagaa gactgaaaat ttgactccag
     3901 actaggttag tcaaaaagaa ggaattcaag caaaacaaat tgttattaag attacagatc
     3961 aaggttatgt aacttctcat ggcgatcatt atcactacta taatggtaaa gttccttttg
     4021 atgcgctctt tagtgaagag ccattaatga aagcccccaa ctatcagccg aaagatcaag
     4081 atattgtcag ttaggttaag ggaggatata ttattaaggt agatggaaag tattatgttt
     4141 accttaaaga tcaagctcat gcagaaaatg tacgaacaaa agatgaaatc aatcgccaaa
     4201 aacaagaaca tggtaaagac gataaaggag ctagtgcaga agtatctgta gcaaaattac
     4261 agggacgtta tactaccgat gatggttata tatagtgagt tgaatttaga atagcacatc
     4321 atagtttcta aatcattgtt agaaattact ttaaaatccc cttatcaatt tgctcatatt
     4381 ctatttcaat ctactaatag taccacatgg tggtcactat catttcattc ctgagagtga
     4441 cttgtcggca ggtgaattag cagccacata tgtctttaac cctaatgata ttgtcagaga
     4501 tataggtgat gcttatatag taagacatgg ggaacactat cactatattc ctaagtcatc
     4561 tcttaacaat cccccatcac actctaacac ggaagaggta ggaagttctt ctagttctgt
     4621 attaagtaat ccgtcactac atgtccacca tgaggaagaa gatggtcatg gtttttgatg
     4681 ccaatcgaat tataagtgaa gattcagaag gttttgtgat tcctcatggc gaccacaatc
     4741 actacatcaa ggttcaaact aagggatatg aagcggcttt gaaaaacaag attccatccc
     4801 tgcaatccaa ctatcaacct ggaacttttg atgagaaggc agtcttggca aaagtagatc
     4861 aacttctagc tgatagcaga agcatctaca aagacagatt gagttagctt taggtcagtt
     4921 tactgaaagt ttgaaaaaaa taaaagttag ttgattgatt acttctctaa attttgggca
     4981 cactaaaaag aggtcttgac acctaaactt taaaattaaa gcatattgaa tccgtgctgc
     5041 tgtgcgaagc gaatagcgtc ttggacgaac attgtcttat ctggatttct tatttctgta
     5101 aggccttgta atcttggatt ataactctcc tgttttagga gtacatggta gatagcaacc
     5161 aataatctgc gacagatagc aaggaagaag tagaaagtct tttgaacaag gcaaatcaac
     5221 tcttggaaca aatccatgaa gaaggaatca gacaatcctt ggcagaagaa gtagaaaatc
     5281 taaaagctgc cacaaacaag gctgatgcag acttggatga agtaaacagt caggtaaaag
     5341 atgttttgac tcgtatcgct agcgcccttc aacaagaaaa ggaaaatgct gagcaagatt
     5401 ctcagacact tgtactctat caaaaactct acgatattct catgtcgctt cactcttatt
     5461 tagaaagtaa taatggatct gatgcggact ttgataaggt ggatgcatta ttagatcaac
     5521 tttctgctaa tagtaaagac aaaacagctt tacttgaatc gacaaaagct attctagttt
     5581 tgaatcatca aatccagtca aaagttagcg caagtgaaga aacaagtcca gcaagaaatg
     5641 ctgaagcaaa tagtgataac accagtgctg agaaccaacc aaacgcaact gcagaatcta
     5701 acattgaaac tgctagcgac gaaaacaaac caagcaatac aagagattct aaacctgctg
     5761 aatcaacttc agaaaatgaa acaacagaat cttctacaac tactggaaat caagaaaaac
     5821 cagtagaata aaaagaaagg cgaagtagct gagccacctc gtctttttag cctttataag
     5881 ctacgatgcc aatgatggta tcaactgcac gttccatagt ctgaaggcta acgtattcaa
     5941 aacgtccgtg catattttcg ccacctgcaa agatattcgg agttgggatt cccataaagg
     6001 aaatcttaga gccgtctgtt ccaccccgga ttggttcgat aataggcgtg atacctagat
     6061 cttccataac ggctttagca atggtaattg gagtcatatc tttttcaatg acttctttca
     6121 tattgtagta ctggtctgtc aagttgagag tgacacggtc gctcccaagt tcttcattca
     6181 tcttatcagc gatagattgc atggatgctt tacgcgcttc aaaggcatct ttttcaaaat
     6241 cacgaatgat gtagcttgca cgcacctcct caacactacc tgtcacatcc attagatggt
     6301 aaaaaccttg gtaaccttca gttaactcag gtcggtcatt ttctggaagt tgattatgaa
     6361 aatcaattgc tagctgaagg gcattgacca tctgcccttt ggcagtacca gggtggacat
     6421 tacggccttg gaaatgcaat tcagcaccag cggctgagaa agtctcgtac tgaagttcac
     6481 ctagtggacc accatcaaca gtgtaggcaa aatccacatc aaaatcttct gcatcaaatt
     6541 tattggcacc aacaccgatt tcttcatctg gaccaaaacc aacacgaatc tcacagtgct
     6601 taatttcagg atgagcagtt agatattcaa tggctgtcat aatttcagca attcctgact
     6661 tgtcatcagc acctagcaag gttgttccat ctgttgtgat gagtgtttgt cctggatatt
     6721 tttcaagact cttgaagtcg gctggatcga gtttgaaacc agaattccct agttcaatca
     6781 caccaccatc gtagttttca attacctgtg gattgactcc ttcagcatta aaatcagcag
     6841 tatccatgtg cgatataaaa ccaatcttac gtgttaaaga cggatcgttg gctggcaagg
     6901 ttccaatagc aaaaccattc ggtagatagt aaacattttg cagtccaaca cgtttcattt
     6961 caggaattag gacatttgtt gcgaagtcaa cctgactctg tgtacttgga gtagtagtag
     7021 agtgttcatc agagcgcgtg ttgaccttaa cgtaggttaa gaagcggtcc aagagatttg
     7081 gataagtcat aaaaaaactc cttttttatc ataaaataga atacaaaact tcggaaaaat
     7141 atgatttgag aaattttatg aattttgaaa aaatataata attcaaattc agaagacttt
     7201 c
//
LOCUS       DAVLBN010000084         6853 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLBN010000084 DAVLBN010000000
VERSION     DAVLBN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.084"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..461
                     /locus_tag="VXC24_001979"
                     /pseudo
     CDS             1..461
                     /locus_tag="VXC24_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            628..828
                     /locus_tag="VXC24_001980"
     CDS             628..828
                     /locus_tag="VXC24_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494045.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            853..1269
                     /locus_tag="VXC24_001981"
     CDS             853..1269
                     /locus_tag="VXC24_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494046.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1500..2207
                     /gene="ccdA2"
                     /locus_tag="VXC24_001982"
     CDS             1500..2207
                     /gene="ccdA2"
                     /locus_tag="VXC24_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0494047.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2218..2775
                     /gene="sdbB"
                     /locus_tag="VXC24_001983"
     CDS             2218..2775
                     /gene="sdbB"
                     /locus_tag="VXC24_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0494048.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2896..4287
                     /locus_tag="VXC24_001984"
     CDS             2896..4287
                     /locus_tag="VXC24_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0494049.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4430..5347
                     /gene="adcAII"
                     /locus_tag="VXC24_001985"
     CDS             4430..5347
                     /gene="adcAII"
                     /locus_tag="VXC24_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0494050.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5355..>6853
                     /locus_tag="VXC24_001986"
     CDS             5355..>6853
                     /locus_tag="VXC24_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0494051.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2122 a         1247 c         1431 g         2053 t
ORIGIN      
        1 agatagactt aaaaactatc ttactgacaa tccagacgct tatttgactg aaatagcttc
       61 tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg gctacactcg
      121 aaaaaagaac cacacctact atgaacaaga cccagaaaaa gtagccttat ttcttaagaa
      181 ttttaatagt ttaaagcacc tagcacctgt ttagattgac gaaacaggat tcgatactta
      241 tttttatcga gaatatggtc gctcattaaa aggtcagtta agaagaggca aagtatctgg
      301 aagaagatat cagagaattt ctttggttgc aggtctaaca aatgaatggt gagttaatcg
      361 ctccaatgac ttacgaagag acgatgacga gcgacttttt tgaagtatgg tttcagaaat
      421 ttctcttacc aacattaacc acaccatcgg ttattatagt aaaatggaat aagaacagga
      481 caaatcgatc aggacagtaa aatcgaattc taacaatgtt ttagaagtct atatgtacta
      541 ttctagtttc aatataccat aactgctcct agtcaacctg caagtcctgt cccagctcca
      601 agctcagctc cgactcaaga tcctagagtg gtagcaagcg cttcggctag ctcaacgagc
      661 acacaagctc aagagcaagt tgacaagtct gaacttcgtg ccttgagtca agagttagac
      721 caacgcttga aagctttggc aacagtatct gatccaaaaa tcgatgcaac caaggctgtc
      781 ctcctagatg ctcaaaaagc tccggaagat agtgccttga cagagtaagg tctgcatact
      841 gcagtagagt ctgtgaaggc tgccttggac tctctcaaag atgtgaaagc aaatgctagc
      901 gacagcaagc ctgcacagga caagaaggat gcaaaacaag gaacggaaga tagtaaggat
      961 tcagataaga tgactgaaac aaactcagtt ccggcaggag tgattgtggt cagtctactt
     1021 gccctcctag acgtgattgc cttctggctg attcgccgta agaaagagtc agaaatccag
     1081 caattaagca cggaattgat caaggttcta ggacagctag atgcagaaaa agcggataaa
     1141 aaagtccttg ccaaagccca aaaccttctc caagaaaccc ttgatttcgt gaaagaagaa
     1201 aatggctcag cagagacaga aactaaacta gtagaggagc ttaaagcaat ccttgacaaa
     1261 ctcaagtaaa acatgattta tgaaatgtca gacctaaaag acattttcgt tcacaaaagc
     1321 agtgacgagt aatccttgtc gttgcttttt ggctattttg ggggataaga tccgccttga
     1381 ctagcaaaag aaaagattgg tccaatagtg cccgatacga ttttgcgtag cagaaagctt
     1441 acaaataaaa ttgaatatag taaaatagga ttagaattat taagaaagtt ggttctttat
     1501 tggaaacgat agtattttta atctctgttt ttctagcagg tgttttatcc tttttttctc
     1561 cttgtatttt tcctcttctg ccagtctatg ctgggatttt attggatgat caagaaagtg
     1621 caaaaagctt ttctttgttt gggagaaagg ttctctggtc aggcttgatt cgaacacttt
     1681 gctttatcgc tggtatctct ctcattttct ttattctagg ctttggtgct ggttactttg
     1741 gtcatattct ctatgcaaat tggtttcgat atgtcatggg agctattatt atcattttgg
     1801 gtcttcacca gatggaaatt tttcatttga agaaattaga agttcaaaaa agttttacct
     1861 ttaaaaaatc agattctaat cgttattggt cagctttttt acttggtatt acctttagct
     1921 ttggttggac accttgtatt ggtccagttt taagttctgt tttagcactt gcggcttctg
     1981 gaggcaatgg tgcttggcaa ggagcgattt atactctcat ttacactctg ggcatggccc
     2041 ttcctttctt ggtcttggca ctagcttcag gtctagtcat gccatatttt agtaaaatca
     2101 agcgtcatat gatgctacta aagaaaattg gtggtttcct cattgtttta atgggaattt
     2161 tgttactatt aggacaagta aatgttctag ctggaatttt tgaataaagg aggacaaatg
     2221 aaaaaagtaa tgtttgctgg cttaagtctc ttgtcattag ttgtattgat ggcctgtggt
     2281 gaggaagaaa ctaaaaagac tcaagcagca caacagccaa aacaacaaac gactgtacaa
     2341 caaattgctg ttggaaaaga tgctccagac ttcacattgc aatccatgga tggcaaagaa
     2401 gttaagttat ctgattttaa gggtaaaaag gtttacttga agttttgggc ttcatggtgt
     2461 ggtccatgca agaaaagtat gccagagttg atggaactag cggcgaaacc agatcgtgat
     2521 ttcgaaattc ttactgtcat tgcaccagga attcaaggtg aaaaaactgt tgagcaattc
     2581 ccacaatggt tccaggaaca aggatataag gatatcccag ttctttatga taccaaagca
     2641 accaccttcc aagcttatca aattcgaagc attcctacag aatatttaat tgatagccaa
     2701 ggaaagattg gaaagattca atttggtgct atcagtaatg cggatgcaga agcagcattt
     2761 aaagaaatga actagaatcg ataaaatctg attacaagat gtagtcagat ttttttagaa
     2821 aaacatttta taaatattca catatctcct atatttatgg taaaatagaa ttatcagttt
     2881 attttggagt caaagatgaa tatatttaga acaaagaatg ttagtttaga taaaacagag
     2941 atgcataggc atttgaagtt atgggatttg attttgctgg gtatcggagc catggtaggg
     3001 acaggcgtct ttacaatcac aggtactgca gctgcaacac ttgctggccc agccctagtg
     3061 atttcaatcg ttatttctgc cttgtgtgtg ggattatcag ccctcttttt tgcagaattt
     3121 gcctcgcgag tacccgctac aggaggtgcc tatagttacc tctatgctat cttaggagaa
     3181 ttccctgcct ggttggctgg ttggttaacc atgatggagt tcatgacagc catatcaggc
     3241 gtagcttcgg gttgggcagc ttattttaaa ggcttgctct ctcaatacgg gatagccttt
     3301 cctcaggctt taaatggtac ctttaatcct caagcaggga catttgttga tttattgcct
     3361 attcttgtct tggtcttggt gacttcgctt gttttactaa atgccaaggc agccttacgc
     3421 tttaattcga ttctagttat tttgaaattt tccgctttag ctctctttgt tttagtagga
     3481 atttggaata ttaagtttga taattggagc aattttgctc cttacggttt tggacaaatc
     3541 tatggagcta gcactggtat tatggctggt gcgtccttga tgttcttcgg ttttttggga
     3601 tttgaatcca tctctatggc tgtagatgaa gtcaagactc ctcaaaaaaa tattcctaga
     3661 gggattgtct tatcgctttc tatcgtaacc attctctatg ccttggtgac ccttgttttg
     3721 actggtgtgg ttcactatag tcatttaaat gtcgatgatg ccgttgcctt tgcccttcgt
     3781 agtgttggga ttagttgggc agccaactat gtgtcattag tggctatctt gaccttgatt
     3841 acagtttgta tttcgatgac ctatgcccta tcgcgtatga tttacagttt agcacgtgac
     3901 ggcttagtgc ctgctgcctt taaggaactg acgaagacta gcaagatacc aaagaatgct
     3961 actatcttga caggtctagc ttcagcagta gcagcaggaa tgttcccact agccagtatt
     4021 gcagcctttt taaatatttg taccttagcc tacttgatca tgctggctta tggtctgatt
     4081 cgcttacgga aagaaaaagg aatgcccaaa gctggggaat ttaaaacacc attggtacct
     4141 ctgttaccaa ttttatcgat catcatttgt ttatccttca tgttacagta taatatgaac
     4201 acctggattg ctttcctagt tgcgttgtta gtaggaagta ttatttactt cacttatggc
     4261 tataagcatt ctaccataga agaataaagt gaaagtctat tgagttgttg acactcagta
     4321 gatttttata tgtgaaagaa atttcaaatt ttttctaaaa atatcttgac agattaaatt
     4381 ttcaggagta gaatatttac tagttaatta aatggttaag gagttgttca tgaagaaaca
     4441 aaatttattt ttagtcctgt taagtgtctt tcttttgtgt ttgggggctt gtggtcaaaa
     4501 ggaaagtcag acaggaaagg ggatgaaaat tgtgaccagt ttttatccta tctacgctat
     4561 ggttaaggaa gtatctggtg acttgaatga tgttcggatg attcagtcaa gtagtgggat
     4621 tcactccttt gaaccttcgg caaatgatat cgcagccatc tatgatgcag atgtctttgt
     4681 ttaccattct catacactcg aatcttgggc aggaagtctg gatccaaatc taaaaaaatc
     4741 caaagtgaag gtcttagagg cttctgaggg aatgaccttg gaacgtgtcc ctggactaga
     4801 ggatgtggaa gcaggggatg gagttgatga aaaaacgctc tatgaccctc acacatggct
     4861 agatcctgaa aaagctggag aagaagccca aattatcgct gataaacttt cagaggtgga
     4921 tagtgagcat aaagagactt atcaaaaaaa tgcgcaagcc tttatcaaaa aagctcagga
     4981 attgactaag aaattccaac caaaatttga aaaagcgact cagaaaacat ttgtaacaca
     5041 acatacagcc ttttcttatc tagcgaagag atttgggctt aatcaacttg gtattgcagg
     5101 tatctctcct gaacaagaac caagtccacg acaactaaca gaaattcagg aatttgttaa
     5161 gacctataag gttaaaacga tttttacaga aagtaacgct tcttcaaaag tagctgaaac
     5221 tcttgtcaaa tcaacaggtg tgggtcttaa aactctgaat cctttagagt cagacccaca
     5281 aaatgacaag acctatttag aaaatcttga agaaaatatg agtattctag cagaagaatt
     5341 aaagtgagga aagaatgaaa atcaataaaa aatatctagc aggttcagtg gcagtccttg
     5401 ccctaagtgt ttgttcctat gaacttggtc gtcaccaagc tggtcaggtt aagaaagagt
     5461 ctaatcgagt ttcttatata gatggtgatc aggctggtca aaaggcagaa aatttgacac
     5521 cagatgaagt cagtaagaga gaggggatca acgccgaaca aattgttatc aagattacgg
     5581 atcaaggtta tgtgacctct catggagacc attatcatta ctataatggc aaggttcctt
     5641 atgatgccat catcagtgaa gaacttctca tgaaagatcc gaattatcag ttgaaggatt
     5701 cagacattgt caatgaaatc aagggtggct atgtgattaa ggtagacgga aaatactatg
     5761 tttaccttaa agatgcagcc catgcggaca atattcggac aaaagaagag attaaacgtc
     5821 agaagcagga acgcagtcat aatcacaact caagagcaga taatgctgtt gctgcagcca
     5881 gagcccaagg acgttataca acggatgatg ggtatatctt caatgcatct gatatcattg
     5941 aggacacggg tgatgcttat attgtccctc acggcaatca cttccactat attcctaaga
     6001 gtgatttgtc tgccagtgaa ttagctgctg cccaagccta ttggaatggg aagcagggat
     6061 ctcgtccttc ttcaagttct agtcataatg caaatccagc tcaaccaaga ttgtcagaga
     6121 accacaatct gactgtcact ccaacttatc atcaaaatca aggggaaaac atttcaagcc
     6181 ttttacgtga attgtatgct aaacccttat cagaacgcca tgtagaatct gatggcctag
     6241 tatttgatcc ggcacaaata acatatcgta cagtcaatgg tgttgctgta ccgcacggag
     6301 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
     6361 tgattgctgt taagggacaa aatggtgcag tcttgccagg aatgcattat ttgaaaccag
     6421 caccaaaacc gcaagttcaa ccatcaactg agaaaaaaca aactgatttt gcagtagaac
     6481 aggttgttag aaaagttgga gaaggctatg ttgtggaaat tgctggtgtc agtcactatg
     6541 tttttgctaa agacttggct aaggataaga ttgatgctat tgaaaatctc ttgtctaaga
     6601 aaactcaaga gacacatgct ctagttgcta aaaaagaaaa tgtcgctcct cgtgaccaag
     6661 aattttatga taaagcttac aatctgttaa cccaggctca taaagtcttg tctgaaaata
     6721 aaggtcgtac ttctgatttc caagccttag acaaattagc agaacgcttg aataatgaat
     6781 cttctaataa agtaaaattg gtagatgatt tattggcatt cctagcacca attacccacc
     6841 cagaacgcct tgg
//
LOCUS       DAVLBN010000085         6845 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLBN010000085 DAVLBN010000000
VERSION     DAVLBN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6845
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.085"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(102..377)
                     /locus_tag="VXC24_001987"
     CDS             complement(102..377)
                     /locus_tag="VXC24_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0494052.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(484..1323)
                     /locus_tag="VXC24_001988"
     CDS             complement(484..1323)
                     /locus_tag="VXC24_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0494053.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1465..2313
                     /locus_tag="VXC24_001989"
     CDS             1465..2313
                     /locus_tag="VXC24_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0494054.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2406..3323)
                     /locus_tag="VXC24_001990"
     CDS             complement(2406..3323)
                     /locus_tag="VXC24_001990"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0494055.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3669..3877
                     /locus_tag="VXC24_001991"
                     /pseudo
     CDS             3669..3877
                     /locus_tag="VXC24_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4187..4480)
                     /gene="rpmA"
                     /locus_tag="VXC24_001992"
     CDS             complement(4187..4480)
                     /gene="rpmA"
                     /locus_tag="VXC24_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0494056.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4497..4841)
                     /locus_tag="VXC24_001993"
     CDS             complement(4497..4841)
                     /locus_tag="VXC24_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0494057.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4857..5171)
                     /gene="rplU"
                     /locus_tag="VXC24_001994"
     CDS             complement(4857..5171)
                     /gene="rplU"
                     /locus_tag="VXC24_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0494058.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5207..5294)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5359..6057)
                     /locus_tag="VXC24_001995"
     CDS             complement(5359..6057)
                     /locus_tag="VXC24_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0494059.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6459..6758
                     /locus_tag="VXC24_001996"
     CDS             6459..6758
                     /locus_tag="VXC24_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0494060.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2145 a         1385 c         1142 g         2173 t
ORIGIN      
        1 gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa gcctactgac
       61 caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac agcgtcttta
      121 agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat ttctttacca
      181 gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt accaaaaccg
      241 atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa tacagcttca
      301 actgctgctg ctgagtcttt cttagttaat tctgtagctt ctgctacttt agcgatcaaa
      361 tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac aaatataatc
      421 atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat tttatttatt
      481 tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt gagtttgaat
      541 aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta agctttcttt
      601 catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg ctacagcacg
      661 ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag ttccacgacc
      721 tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga tattgagaag
      781 agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat tttccaaagt
      841 tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag ataaaattgc
      901 ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga atttcagggc
      961 ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc tagcaccttg
     1021 gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa gaatctggcc
     1081 accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg gctgacttgt
     1141 tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt ctttcaaatc
     1201 cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg taatatctaa
     1261 ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct taatttttgt
     1321 catagtatca atctttctat tttaggattc agattggttt ccttacttct aattatatca
     1381 aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt tgatataatc
     1441 aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt taccatttta
     1501 ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca tcatctcttt
     1561 gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat ccctgtttcc
     1621 ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat ctttggagcc
     1681 aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt agcttttttt
     1741 gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc ccttatagcg
     1801 ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac aactggcgga
     1861 actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg aaaactgctc
     1921 tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga tttgagattg
     1981 gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt gattggtgaa
     2041 ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca acttgctaag
     2101 gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg ctactatagt
     2161 aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt gaaaacgaag
     2221 gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc ccatgaaatc
     2281 ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg acctcaaaag
     2341 ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt tatttactca
     2401 agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc cactaattgg
     2461 tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac catgacggtt
     2521 tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc ttcttctcca
     2581 tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct ttgaatctca
     2641 acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag cactaaattc
     2701 gctgtcggat aaccaattgt acgaccacga gcattaccat gaactaccat acctcttgat
     2761 ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa aatagcttga
     2821 cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac aatgataact
     2881 tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc aaatgtataa
     2941 tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc aaagaattct
     3001 tgtgcagtaa gactagcgaa ttgactacta aaatcaagga gatataattc ttctacacct
     3061 tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa caaatctgga
     3121 tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac gataggtaat
     3181 aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc cttatgtatg
     3241 ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc tttttggttt
     3301 tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta tttctggaac
     3361 agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa aagcacttta
     3421 ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg taggacatct
     3481 tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc atactatgtt
     3541 atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat tggtgccgaa
     3601 aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa tgagacaact
     3661 tgggcaagat gtttgaagaa tttcctaaac tcccatctag tgtgcttcag actaggctat
     3721 ttttctctcc atctgttagc ttggattctc agaccgtttc agctaaagaa tatcttttcc
     3781 cttatcagaa ggaacggctc aagccattca gacaagtgaa gggacgacaa gccaatattt
     3841 gaaaccagat agcagttctt atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa
     3901 actcatatca atttttaaca gtgttctatt ccagattcat actcaatgaa aattaaagtg
     3961 caaactagga agttagccgc aggctgtact tgagtacggc aaggtgaaat tgacgtggtt
     4021 tgaatttgat tttcgaagag tatcaatcca ctatacatat taaaaagtat gggtatcaaa
     4081 ataaaaaaca ggctctccga aaactcggaa agccttattt taagctgttt ctagcttcct
     4141 cacctttaca tttcaaggtt cgggataaaa ggttcaatgg acctttttat ttagcgattg
     4201 ggtaaacaga aacttgtttt ttatcgcgtc ctttacgttc aaagcgtact acgccttcaa
     4261 ctttagcgaa caaagtatcg tctccaccac gaccaacgtt tacacctgga tagatgtgtg
     4321 taccacgttg acggtaaagg attgatccac ctgttacagt ttgtccgtca gctgctttag
     4381 ctccaagacg ttttgcttgt gaatcacgtc cgtttgatgt agaacctcca ccttttttgt
     4441 gggcgaaaag ttgcaagttg ttaagagtca tttttaacat aatgttttcc tccgtgttag
     4501 ttttctgtga taactctggt ttggacgaac tcagaatagt tctccgataa gtttgccata
     4561 cctaagaaaa atgattcaaa gaataactgg gtcatttctc tctggtgtga aggaagatct
     4621 tttggtattt caaccatcag atagccacct tcatcttcgt ttaattctag gattggttca
     4681 tagcctgcaa atttctcaat agaattgata aagttaatgg caagcgtaga aaccgatgca
     4741 cacacgacat ctaagccgta ttcgccactc tcggcgtgtc cagtaatttc cgcactcctc
     4801 agctcgccat cttcggctct ctcaaagact gcctgtatca tgtgttctcc ttaaaattaa
     4861 gcgttgattg cgttgatgac aacttttgta tatggttgac ggtgaccttg tttacggtgg
     4921 ctaccttttt taggtttgta cttgtaagta accactttct tttgttttcc ttgtttttca
     4981 acagttccaa ctacagtagc tccagcaaca agtggagttc cgacaacagt gttttcacca
     5041 ccaacaagaa caacttcgtt aaaagtaact tcttgaccag cttcaacgtt caatttttca
     5101 acgtaaactg cttgaccaac ttcaacttta acttgttttc cgccagtttt gataattgcg
     5161 tatgtgctca ttatgcacct cctatgattt ttatgggttt ccccgatttt ttgtgaagac
     5221 tcgcctagca tcgtgggacg aaccacttaa acttgaataa tcaagcaacg atgttcgtgc
     5281 ggttgcacag gatcgtgcat agtcaactct tcaagtatag catatctcct attttcttac
     5341 aagtaataac acctaaaatc aagctttttc ttttactttt ttctgccaag aggcaaaaag
     5401 catgctgagg taaaaaacgc tcatcataat aggaacacca agaatggtct tttcatgata
     5461 gaaaatcgtc aaataggctg aaaagacaac gccaaggaca aaactactaa gcaggctaac
     5521 aaatatgaat ccttcacgca aaaaaggagt gtgcttggtt cggaaataat ctccaaaagc
     5581 cagcatggtc cgtttgatat tccctgtcat aaaagcgtta ttataggcaa tacccgacac
     5641 ttctccaaaa gcagttgtca ccagtcccat acagaaggcc aagggcggca ctagatagat
     5701 attatccaca gtttgcggca caaaagcaat aatgattgat aagattgcca agggaatcaa
     5761 ggacagaata ggttttttca caattctcaa tttttcctta taaatcgtta ataaaaagac
     5821 tcccatcata aacgctagca aggtgagaac cttgtcccta acatccgaaa cattattttt
     5881 aattaattct actgaaagaa agacaacatt tccagtttgt ccagctacaa gggtattccc
     5941 gcgaacaata aaagtgtaag catccacata tccagcacaa aacgtcaaaa aaagtgctaa
     6001 ccttttagac tgacgtgata tttttcttat aggtaataac ctcattttac ctcccattgt
     6061 attttctctt agaaatattg taccattttc tttctaaaaa atcgtaggct accatttaga
     6121 ttttactatt agcataaaaa taataataga caactattta tccaaaaata gatagatgta
     6181 acatgtttgc aaacaaagca tacgaacctt tagtaaaatc atttccatga aactagaata
     6241 gagccctctt agcaaaaatc attattttaa tttatttcta atcactcctt gacataaata
     6301 actctcacca ataaaagact atgtcttaaa aaaatggtat aataaaatca atacttgggc
     6361 ttgatggcta tgctactaat aacaattagg agagaaaatc aggcacttgt taacaacaag
     6421 gattatcccc ttgagatgaa aggaacttta gaaatcttat gatgaacatg caaaacatga
     6481 tgcgtcaagc acaaaaactt caaaaacaaa tggaacaaag ccaagctgaa cttgctgcta
     6541 tgcaatttgt tggcaaatct gctcaagatc ttgtccaagc gaccttaact ggcgataaga
     6601 aagttgtcag cattgatttc aatccagctg tcgttgaccc agaggacctt gagactcttt
     6661 ctgatatgac cgttcaagcc atcaactctg ctcttgaaca aatcgatgaa actaccaaga
     6721 aaaaactggg tgctttcgct gggaaattac ctttctaaaa acaaggagct agaacaatgc
     6781 ttgtcgataa caaaggctaa gaaaggtgca aaaatgactc tataatattt gtagtgggta
     6841 aatcc
//
LOCUS       DAVLBN010000086         6829 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLBN010000086 DAVLBN010000000
VERSION     DAVLBN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.086"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            81..6500
                     /locus_tag="VXC24_001997"
     CDS             81..6500
                     /locus_tag="VXC24_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0494061.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
BASE COUNT         2703 a          919 c         1326 g         1881 t
ORIGIN      
        1 gtaaaacttt ttataacaaa ggctagcaaa gttaaagttt attatctatt ggaagttata
       61 taaatatgta aggaattaaa atgaaaaaaa gtacagtatt gtcattaacc acagctgcag
      121 ttattttagc agcctatgcc cctaatgagg tagtcttagc agacacatct agctctgaag
      181 atgctttaag catctctgat aaagaaaaag tagcagaaaa taaagagaaa cataaagata
      241 ttcataatgc tatagaaact tcaaaggata ctgaagaaaa gaaaacaaca attattgagg
      301 aaaaagaagt tgttagtaaa aatcctgtga tagacactaa aactagcaat gaagaagcaa
      361 aaatcaaaga agaaaattcc aataaatccc aaggagatca tacggactca tttgtgaata
      421 aaaacacaga aaatcccaaa aaagaagata aagttgtcta tattgctgaa tttaaagata
      481 aggaatctgg atcaaaagca atcaaggaac tatccagtct taagaataca aaagttttat
      541 atacttatga tagaattttt aacggtggtg ctattgaaac aactcaagat aatctgaata
      601 aaattaaaca aatagaaggt attacatcgg ttgaaagggc acaaaaagtc caacccatga
      661 tgaatcatgc cagaaaggaa attggagttg aggaagctat tgattaccta aagtctatca
      721 atgctccgtt tgggaaaaat tttgatggta gaggtatggt catttcaaat atcgatactg
      781 gaacagatta taggcataag gctatgagaa tcgatgatga tgccaaagcc tcaatgagat
      841 ttaaaaaaga agacttaaaa ggaactgata aaaattattg gttgagtgat aaaatccctc
      901 atgcgttcaa ttattataat ggtggcaaaa tcactgtaga aaaatatgat gatggaaggg
      961 attattttga cccacatggg atgcatattg cagggattct tgctggaaat gatactgaac
     1021 aagatatcaa aaactttaac ggcatagatg gaattgcacc taatgcacaa attttctctt
     1081 acaaaatgta ttctgacgca ggatctgggt ttgcgggtga tgaaacaatg tttcatgcta
     1141 ttgaagattc tatcaaacac aacgttgatg ttgtttcggt atcatctggt tttacaggaa
     1201 caggtcttgt aggtgagaaa tattggcaag ctattagggc attaagaaaa gcaggcattc
     1261 caatggttgt cgctacgggt aactatgcga cttctgcttc aagttcttca tgggatttag
     1321 tagcaaataa tcatctgaaa atgaccgaca ctggaaatgt aacacgaact gcagcacatg
     1381 aagatgcgat agcggtcgct tctgctaaaa atcaaacagt tgagtttgat aaagttaaca
     1441 taggtggaga aagttttaaa tacagaaata taggggcctt tttcgataag aataaaatca
     1501 caacaaatga agatggaaca aaagctccta gtaaattaaa atttgtatat ataggcaagg
     1561 ggcaagacca agatttgata ggtttggatc ttaggggcaa aattgcagta atggatagaa
     1621 tttatacaaa ggatttaaaa aatgctttta aaaaagctat ggataagggt gcacgcgcca
     1681 ttatggttgt aaatactgta aattactaca atagagataa ttggacagag cttccagcta
     1741 tgggatatga agcggatgaa ggtactaaaa gtcaagtgtt ttcaatttca ggagatgatg
     1801 gtgtaaagct atggaacatg attaatccta ataaaaaaac tgaagtcaaa agaaataata
     1861 aagaagattt taaagataaa ttggagcaat actatccaat tgatatggaa agttttaatt
     1921 ccaacaaacc gaatgtaggt gacgaaaaag agattgactt taagtttgca cctgacacag
     1981 acaaagaact ttataaagaa gatatcatcg ttccagcagg atctacatct tgggggccaa
     2041 gaatagattt acttttaaaa cccgatgttt cagcacctgg taaaaatatt aaatccacgc
     2101 ttaatgttat taatggcaaa tcaacttatg gctatatgtc aggaactagt atggcgactc
     2161 caatcgtggc agcttctact gttttgatta gacctaaatt aaaggaaatg cttgaaagac
     2221 ctgtattgaa aaatcttaag ggagatgaca aaatagatct tacaagtctt acaaaaattg
     2281 ccctacaaaa tactgcgcga cctatgatgg atgcaacttc ttggaaagaa aaaagtcaat
     2341 actttgcatc acctagacaa cagggagcag gcctaattaa tgtggccaat gctttgagaa
     2401 atgaagttgt agcaactttc aaaaacactg attctaaagg tttggtaaac tcatatggtt
     2461 ccatttctct taaagaaata aaaggtgata aaaaatactt tacaatcaag cttcacaata
     2521 catcaaacag acctttgact tttaaagttt cagcatcagc gataactaca gattctctaa
     2581 ctgacagatt aaaacttgat gaaacatata aagatgaaaa atctccagat ggtaagcaaa
     2641 ttgttccaga aattcaccca gaaaaagtca aaggagcaaa tatcacattt gagcatgata
     2701 ctttcactat aggcgcaaat tctagctttg atttgaatgc ggttataaat gttggagagg
     2761 ccaaaaacaa aaataaattt gtagaatcat ttattcattt tgagtcagtg gaagaaatgg
     2821 aagctctaaa ctccaacggg aagaaaataa acttccaacc ttctttgtcg atgcctctaa
     2881 tgggatttgc tgggaattgg aaccacgaac caatccttga taaatgggct tgggaagaag
     2941 ggtcaagatc aaaaacactg ggaggttatg atgatgatgg taaaccgaaa attccaggaa
     3001 ccttaaataa gggaattggt ggagaacatg gtatagataa atttaatcca gcaggagtta
     3061 tacaaaatag aaaagataaa aatacaacat ccctggatca aaatccagaa ttatttgctt
     3121 tcaataacca agggatcaac gctccatcat caagtggttc taagattgct aacatttatc
     3181 ctttagattc aaatggaaat cctcaagatg ctcaacttga aagaggatta acaccttctc
     3241 cacttgtatt aagaagtgca gaagaaggat tgatttcaat agtaaataca aataaagagg
     3301 gagaaaatca aagagactta aaagtcattt cgagagaaca ctttattaga ggaattttaa
     3361 attctaaaag caatgatgca aagggaatca aatcatctaa actaaaagtt tggggtgact
     3421 tgaagtggga tggactcatc tataatccta gaggtagaga agaaaatgca ccagaaagta
     3481 aggataatca agatcctgct actaagataa gaggtcaatt tgaaccgatt gcagaaggtc
     3541 aatatttcta taaatttaaa tatagattaa ctaaagatta cccatggcag gtttcctata
     3601 ttcctgtaaa aattgataac accgccccta agattgtttc ggttgatttt tcaaatcctg
     3661 aaaaaattaa gttgattaca aaggatactt atcataaggt aaaagatcag tataagaatg
     3721 aaacgctatt tgcgagagat caaaaagaac atcctgaaaa atttgacgag attgcgaacg
     3781 aagtttggta tgctggcgcc gctcttgtta atgaagatgg agaggttgaa aaaaatcttg
     3841 aagtaactta cgcaggtgag ggtcaaggaa gaaatagaaa acttgacaaa gacggaaata
     3901 ccatttatga aattaaaggt gcgggagatt taaggggaaa aatcattgaa gtcattgcat
     3961 tagatggttc tagcaatttc acaaagattc atagaattaa atttgctaat caggctgatg
     4021 aaaaggggat gatttcctat tatctagtag atcctgatca agattcatct aaatatcaaa
     4081 agcttggcga gattgcagaa tctaaattta aaaatttagg aaatggaaaa gagggtagtc
     4141 taaaaaaaga tacaactggg gtagaacatc atcatcaaga aaatgaagag tctattaaag
     4201 aaaaatctag ttttactatt gatagaaata tttcaacaat tagagacttt gaaaataaag
     4261 acctaaagaa actcattaaa aagaaatata aggaagaaga cgactttgta actggtggaa
     4321 aaagaacagt agaacttgat tataaatatg acgataaagg aaatataact gcctatgaag
     4381 atgaaagtgc tctagaatat gaaactgaaa aatttgacga aataaaatca aaaatttatg
     4441 gtgttctaag cccatctaaa gatggacact ttgaaattct tggaaagata agcaatgttt
     4501 ctaaaaatgc caaggtatat tatggaaata actataaatt tatagaaatc aaagcgacta
     4561 agtatgactc acattcaaaa acgatgacat ttgatttata cgctaatatt aatgatattg
     4621 tggatggatt agcttttgct ggagatatgc ggttttttgt taaagatgat gatcgaataa
     4681 aagctgaaac taaaattaga atgcctgaaa aaaataagga aactaaagca gaatatccct
     4741 atgtatcaag ttatgggaat gtaatcgaat taggagaagg agatctttca aagaacaaac
     4801 cagacaattt aactaaaatg gaatctggta aaatctattc tgattcagaa aaacaacaat
     4861 atctgttaaa ggataacatc attctaagaa aaggctatgc actaaaagtg actacctata
     4921 atcctggaaa aacggatatg ttagaaggga atggagtcta tagcaaggaa gatatagcaa
     4981 aaatacaaaa ggccaatcct aatctaagag tcctttcaga aacaacaatt tatgctgata
     5041 gtagaaatgt tgaagatgga agaagtaccc aagctgtatt aatgtcggct ttggacggct
     5101 ttaacattat aaggtatcaa gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg
     5161 ataaagacgg aaatcttgtg acagattctt ctaaacttgt attatttggt aaggatgata
     5221 aagaatacac tggagaggat aagtccaatg tagaagctat aaaagaagat ggctccatgt
     5281 tatttattga taccaaacca gtaaaccttt caatggataa gaactacttt aatccatcta
     5341 aatctaataa aatttatgta cgaaatccag aattttattt aagaggtaag atttctgata
     5401 agggtggttt taactgggaa ttgagagtta atgaatcggt tgtagataat tatttaatct
     5461 acggagattt acacattgat aacactagag attttaatat taagttgaat gttaaagacg
     5521 gtgacatcat ggactgggga atgaaagact ataaagcaaa cggatttcca gataaggtaa
     5581 cagatatgga tggaaatgtt tatcttcaaa ctggctatag cgatttgaat gctaaagcag
     5641 ttggagtcca ctatcagttt ttatatgata atgttaaacc cgaagtaaac attgatccta
     5701 agggaaatac tagtatcgaa tatgctgatg gaaaatctgt agtctttaac atcaatgata
     5761 aaagaaataa tggattcgat ggtgagattc aagaacaaca tatttatgta aatggaaaag
     5821 aatatacatc atttgatgat attaaacaaa taacagacaa gacactaaac attaagattg
     5881 ttgtaaaaga ttttgcaaga aatacaaccg taaaagaatt cattttaaat aaagatacgg
     5941 gagaggtaag tgaattaaaa cctcataggg taactgtgac cattcaaaat ggaaaagaaa
     6001 tgagttcaac gatagtgtcg gaagaagatt ttattttacc tgtttataag ggtgaattag
     6061 aaaaaggata ccaatttgat ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg
     6121 gctatgttat taatctatca aaagatacct ttataaaacc tgtattcaag aaaatagagg
     6181 agaaaaagga ggaagaaaat aaacctactt ttgatgtatc gaaaaagaaa gataacccac
     6241 aagtaaacca tagtcaatta aatgaaagtc acagaaaaga ggatttacaa agagaagatc
     6301 attcacaaaa atctgattca actaaggatg ttacagctac agttcttgat aaaaacaata
     6361 tcagtagtaa atcaactact aacaatccta ataagttgcc aaaaactgga acagcaagcg
     6421 gagcccagac actattagct gccggaataa tgtttatagt aggaattttt cttggattga
     6481 agaaaaaaaa tcaagattaa gataaaagct atagaaaaaa atggtttatg tactgagatt
     6541 agatagtgag gtgatgacat agttttgtga aaacagccat ttataactca attatttagt
     6601 ttacttcact attgatacta tttggagtta ttaatggact tagtttagat aactaatgaa
     6661 ttgattgaaa gggttagtat tgacaatatt ggtcatattg attagaaaat agagtctatc
     6721 aaaatttaaa ggctaataga ggtgatgaga caatttcggc tctttgtcaa ctgtagtggg
     6781 ttgaagtcag ctaagctcga gaaaggacaa attttgtcct ttctttttt
//
LOCUS       DAVLBN010000087         6655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLBN010000087 DAVLBN010000000
VERSION     DAVLBN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.087"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(73..165)
                     /locus_tag="VXC24_001998"
                     /pseudo
     CDS             complement(73..165)
                     /locus_tag="VXC24_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(201..484)
                     /locus_tag="VXC24_001999"
                     /pseudo
     CDS             complement(201..484)
                     /locus_tag="VXC24_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(474..614)
                     /locus_tag="VXC24_002000"
     CDS             complement(474..614)
                     /locus_tag="VXC24_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0494062.1"
                     /translation="MVSCHSSLRSYIAEPILKQAGFTVQNLDGAYSLYKMVNPEGVEY
                     GN"
     gene            706..1470
                     /locus_tag="VXC24_002001"
     CDS             706..1470
                     /locus_tag="VXC24_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0494063.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2035..3414
                     /locus_tag="VXC24_002002"
     CDS             2035..3414
                     /locus_tag="VXC24_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0494064.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3428..4093
                     /locus_tag="VXC24_002003"
     CDS             3428..4093
                     /locus_tag="VXC24_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0494065.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4228..4302
                     /locus_tag="VXC24_002004"
                     /pseudo
     CDS             4228..4302
                     /locus_tag="VXC24_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4448..4987
                     /locus_tag="VXC24_002005"
     CDS             4448..4987
                     /locus_tag="VXC24_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0494066.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5054..5464
                     /locus_tag="VXC24_002006"
     CDS             5054..5464
                     /locus_tag="VXC24_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0494067.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5580..>6655
                     /gene="pavB"
                     /locus_tag="VXC24_002007"
     CDS             5580..>6655
                     /gene="pavB"
                     /locus_tag="VXC24_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0494068.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKA"
BASE COUNT         1813 a         1283 c         1525 g         2034 t
ORIGIN      
        1 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
       61 gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa
      121 cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt
      181 ttttgcccag ctcctcttga ttattctact tgaccgggcc aagcattcat accaccttct
      241 acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact
      301 cctccgtgac aaatgacata gtattcatgg tcaggtttga gttctttgta gccttgctct
      361 aaggtattta tggaagattt ttgggtcctg cttggaattc atgtgcttca cggacatcga
      421 taagttccag attttcattt tgatattttc tataaaagtc agccatgctg atactagttt
      481 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
      541 tggacggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaactactg
      601 tggcaactga cgatgtaggc ttgtttttct cctcagttca tcagcttcct ccttgacact
      661 cggtcagatt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
      721 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
      781 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
      841 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
      901 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
      961 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
     1021 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
     1081 gttcgcgctc tgcgagatga aggagccagt taccactatg tggcaccttc tcgttatatg
     1141 gaaatgcagc cagaggctat tgctgccatt gagcgagttt tggatgatag agggattcct
     1201 tatgaagaag tcatgacctg gtccacagat ggtttttacc gagaaacggc tgaaaaggtg
     1261 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
     1321 gtagctcaat tgcgtggagt tctctggggt gaattgttgt tcacagcaga ttctctagcg
     1381 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcactagaa
     1441 ctgagtttag caagtgttca ccacctttag ttgtactggc aaaggatttg ttttatcata
     1501 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
     1561 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
     1621 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
     1681 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg
     1741 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc
     1801 gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
     1861 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
     1921 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtag
     1981 attttgcctt atcctatcta agtcatttcg aactttttat ggtacaatgg aaacatgtta
     2041 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
     2101 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
     2161 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
     2221 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
     2281 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacctt tattggggtt
     2341 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
     2401 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
     2461 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
     2521 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
     2581 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
     2641 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
     2701 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
     2761 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
     2821 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
     2881 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
     2941 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
     3001 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
     3061 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
     3121 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
     3181 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
     3241 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
     3301 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
     3361 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
     3421 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
     3481 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
     3541 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
     3601 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
     3661 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
     3721 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
     3781 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
     3841 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
     3901 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
     3961 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
     4021 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
     4081 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
     4141 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
     4201 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
     4261 acgggctgct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa
     4321 cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga
     4381 cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga
     4441 gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca
     4501 ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga ttatcaatga
     4561 cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt atcctaatat
     4621 cgttagagcc atctatcagg aaaataaatg ccatggcggt gcggtcaatc gtggcttggc
     4681 agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg atcctcgtgc
     4741 ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag aggtggatgt
     4801 ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga gtatgagtta
     4861 cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa atttctccaa
     4921 aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca
     4981 gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca
     5041 gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga
     5101 ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa
     5161 tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata
     5221 tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca accgatctgg
     5281 aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc
     5341 agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt
     5401 gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa
     5461 ttaatataag tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt
     5521 ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta
     5581 tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg
     5641 ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac
     5701 gtgccgatgt ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga
     5761 aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg
     5821 gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg
     5881 aaacaaactc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc
     5941 cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag
     6001 caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag
     6061 acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg
     6121 ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc
     6181 tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg
     6241 ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg
     6301 gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc
     6361 aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta
     6421 atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaacag
     6481 ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca gcctacctag
     6541 aaaaagccaa gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt ccatacgaac
     6601 tcttcgcagg tgatggtatg ttgactcgtc tcttgctcaa ggcatctgac aaggc
//
LOCUS       DAVLBN010000088         6417 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLBN010000088 DAVLBN010000000
VERSION     DAVLBN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.088"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..287
                     /locus_tag="VXC24_002008"
                     /pseudo
     CDS             1..287
                     /locus_tag="VXC24_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            215..667
                     /locus_tag="VXC24_002009"
     CDS             215..667
                     /locus_tag="VXC24_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494069.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1486..1845
                     /locus_tag="VXC24_002010"
     CDS             1486..1845
                     /locus_tag="VXC24_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494070.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            1855..2220
                     /locus_tag="VXC24_002011"
     CDS             1855..2220
                     /locus_tag="VXC24_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0494071.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2207..4057
                     /locus_tag="VXC24_002012"
     CDS             2207..4057
                     /locus_tag="VXC24_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0494072.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            4313..5745
                     /locus_tag="VXC24_002013"
                     /pseudo
     CDS             4313..5745
                     /locus_tag="VXC24_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(5983..6117)
                     /locus_tag="VXC24_002014"
                     /pseudo
     CDS             complement(5983..6117)
                     /locus_tag="VXC24_002014"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         2223 a         1029 c         1265 g         1900 t
ORIGIN      
        1 acaagaatca tgggttaatc aatggttaag tgaaaatatt ataagtgaga aagatggaag
       61 ttatcaacat tcactgacta taatgaagga tttcaataat caaaaaatag ttaactatat
      121 tgctcatttc aatagttatg acattttgaa aaaaggttct cacttatcag gtgcatataa
      181 acgaaaaatt ttttctaaag aaaatacacg atttttggag tttaatatta actcgaaaga
      241 atcttcgcaa caacttgata ttctctataa agaagttggt gtattaagtt tgggacaaaa
      301 agttgtagcc atgcttgatt ttttattagc atatagtgac tattctaaag acttcagacc
      361 attgattatt gatcagcctg aagacaatct agacaatcgt tatatttaca ggcatttagt
      421 tcagcagttt agagatgtga aagctcaacg tcaaattatt ttagcaacac ataatgctac
      481 aattgtaaca aattctatga cagatcaagt tgttattatg gagtcagatg gagttaacgg
      541 atggattgaa tcacagggat atgttagtga aaaatatata aaaaatcata tcatcaatca
      601 attagaggga ggaaaagatt ccttcaagca taaaatgtct atatatgaga cggctttatc
      661 agagtagagt cagaaaaagt aggttagaaa tttagcctac ttttttcttt gttcgacagg
      721 catagtgtac atctgaggtc caagtcctct gtggatattt gctgcagatg aaaccaatag
      781 cgactcctaa gcctgaatat cgtgaggtag gggggatagg aaggaattag cgaaatcaag
      841 gttctacaaa cagaatcgtg acttgaagcc atatatagcg gatgaggaac tctaaaatcc
      901 aaataggtgt cgtaacctat atacgtaaat tacgagagta aactaggaaa gatgtacggc
      961 ttattccgtg agcgtttagg acgtagtaca acgaatcatg ggagtcagct gaacacatag
     1021 tattgaagaa atttctgtaa tggaaatgga gcgaagaagt gaacaattaa atgaatacct
     1081 ctctaattaa atttgtcaat tctaattcct ggtatgaaaa gacagtgacc taaaaatgta
     1141 aacgatggga gctgatcata aatataggac ggtacatgca gtggtgttag agattagtcc
     1201 ctacttgatt tgtgataact tccccaactt tcttctgcta tacttttctc aacttttaaa
     1261 aatccaacta agaattttac ctgggagttt gggggcgtag ccaccaagtt atcttatggt
     1321 tagctgtcaa aactggaagg ttttggttag ctggcgatat gattttttgg gtattgtgac
     1381 cacaatgcct gagctcgcaa agaccgaaca aggactttaa gaaatttccc gtatgacaca
     1441 cggggtcggg gtttacccga gaaaggatga aagtgaggaa aagagatgtc tgaacagtac
     1501 cgtgacattc gaaaagaggt aaatctaacc gcagatgagc taaaacagat tgaaaaaatg
     1561 atggaggttg ataattatcg tcacttttca ccattcgtca gggataaaat tttgatgact
     1621 gatgacaaac agttagctgc caaagaatgg ttttcccttt ggcagtctca aaagtttgaa
     1681 cagatcagtc gagatgtgca tttggttttg attatcgcaa gagagaatca ccaagtgact
     1741 caagaacacg tgtcaatctt attgacctgc gttcaagaat tgattgcgga agtcaatcaa
     1801 gtacagtcac tcagtcgtgg gtttcgtgaa aaatacatga gataggaggc tactatggtt
     1861 tatcgttatc gtaccaatct caaaaaagta tttctaacag attcagaatt acaccaattg
     1921 aatgaacgga ttgctaagag caattgtcaa aatttttcag tctatgccag aaaagttttg
     1981 cttaatccca atatgtcatt tgtcacgatt aacacggata cttatgacca gttagttttt
     2041 gaattgagac ggatcggaaa taacattaat caaattgcgc gtgctatcaa tcaaagccgt
     2101 ctgatttctc aggaacagtt acaagaattg agtaaaggag tcggagagtt gatcaaggaa
     2161 gtggacaaag aatttcaagt ggaagtgaaa agattgaagg agtttcatgg tagtcactaa
     2221 gcattttgcg acacacggaa aaaaatatcg taggcgttta attaagtata tcctcaatcc
     2281 tgataaaacg gacaatttga aattagtatc tgattttggt atgagcaatt acttagactt
     2341 tcctagctat gaagaaatgg tagaaatgta caatgtcaac tttaccaata atgacaagtt
     2401 gtacgaatac agaaatgacc gacaagaaaa acaccaacaa aatattcatg cccatcacct
     2461 cattcaatca ttttctcctg aagataatct gacacctgaa gaaattaacc gcattggtta
     2521 tgagaccatt atggaattaa caggaggccg ttttcgtttc atcgtagcga ctcatacaga
     2581 caaagatcat attcataatc acatcttaat caacgccatt gactgtaatt cagataaaaa
     2641 gttgatatgg aattatgcct tggaacgaaa ccttcgtatg atttcagacc gcatttctaa
     2701 aatggctggg gcgaaaatta ttgaaaagcg tttctcttac cgtgactatc aaaaatatag
     2761 agcgactagc cataagtttg aactaaagca acgtctttat tttttgatgc agcagtcaaa
     2821 atcctttgat gattttttag aaaaagcaga gcaattacat gttcatattg attttagtca
     2881 gaagcatagt cgattcatga tgacggatcg ggcaatgaca aaaccaattc gaggacgtca
     2941 actcagtaaa cgagatttat atgatgaaga tttttttaga atgcatttta ccaagcaaga
     3001 gattgcaagt cgtttagaat ttttgttgaa ctgtgtcaat tctttagaag ggttactaac
     3061 aaaatcaaaa gaattgaatc taaccattga cttaaaacaa aaaaatgtaa tctttatact
     3121 tgaagaaaat ggaaagcaat tcagtctgag tcataaaaaa ataagtgatg agaaattata
     3181 tgatgtcaat ttttttcaag attattttaa aaataaggaa gtaggtgttt cagaaggaat
     3241 agaaaatcta caggcacagt accgtgcttt tcaagaagaa cgagataagg agaaggtatc
     3301 tactgaagaa attgaggaag cctttgagac atttaaggaa aaacgagatg ccgttcatga
     3361 atttgaagta aaacttacag aacaccaaat tgagaagtta gttgatgagg ggatttatat
     3421 caaagtgtcc tttggtataa atcagagtgg tcttattttc attcctaact atcaactgga
     3481 tattatggaa gaagaaaatc agaaaaaata taaagtctac attcgtgaga caacctcata
     3541 ttttgtctat aacaaagaac attcggataa gaatcagtat atcaaaggga gaaccttgat
     3601 taggcagcta accaacgata gtcgagtaat accatacaga agaccgactg ttgaaagact
     3661 tcaagaaaag atttctgaga ttagcctctt gattgagtta actgagacag ataagaaata
     3721 ccaagacatt aaagacaact tggtttccga aatagcagag ctagatataa aactgactca
     3781 aacaaatgaa aaaattgcca ccttaaataa gatggcggaa gtacttatca attctaagag
     3841 tgaaggttcg ggtagccaaa aactagctag gcatgaattt tctaaattga acatgacaga
     3901 atcaacaact ttagaacaag tcaatgaaga acttttgaag ttacaacagg aatttggtaa
     3961 tgttcttgat gagtatgaga aaacaataag aaagcttgga caattattta aggtttttga
     4021 tgagtgtatc aataaagaaa ttatgaatga aatataaatc agactgaaga caaactcaaa
     4081 tttttttgga tatcttttct gtttatggtt gccaatatcg gtttaacttc taaaacaaac
     4141 attaataaaa atgcattcaa agacgatttt acctatttta cgattacgct tcgaccccaa
     4201 atcattaaag ttgtctatgc tctatcattg catcactgga cttgtcaaga gttaagataa
     4261 ttcggagtcc actgaaaaag tcatcgtatg atggtatact aaagatgagg tgatggtatg
     4321 cttgataatc gatgttagtc cctattctac tctgtgtgat attgttgttc ccaaaactca
     4381 ttttttacga cagctaatgg aactctgtga ttttagtttt atttatgacg agctggaaaa
     4441 gaattatcaa cctgacttcg gatgtcgttc ctactctctc cttatcatga tgttcaagta
     4501 tctcttatta aaagacatct ataagttgtc cgatgtggat gtggtggagc gctccttttc
     4561 tggtatgacc ttcaaatact tccttggtct agctcctgtt attgaaccgt cctcattgac
     4621 taaattccga aaacttcgga acaaagatga acgattactt gatttgctca tcgctaaatc
     4681 tgttcagatt gcgatagagc tcggtctgat taaaagtaac attctcattg tggatgcgac
     4741 tcataccaaa gttcattaca atcacaagaa acctcaagaa gtcctccgag aacgctcaaa
     4801 agccttgcgt aaaacgattt atcagtattc ggaatatatc aaggcagaat ttcctagtaa
     4861 gcctcaggaa gatactctag tagctgaatt aagatataca caagaagtaa tatcagtcct
     4921 tgagaagcat gacgaattga ctggaatacc agctatctca caaaattcaa ttaccttaaa
     4981 gaagctgtag aggatgactt agagcacttg gaatcctctg tcaaagaaga agcaagaatt
     5041 ggacataagt cagccgatag ttccttttac gggtacaaag agcattttgc catgaccgat
     5101 gaacggatta ttactgcctg tgtggtgaca tcgggtgaaa aaagtgatgg tcctgtttta
     5161 gaagaactct atcacaaatc taaggataat ggcgtgacga ttgaagctat tgttggagat
     5221 agggcctact ctgggaagga taatatgcaa tttaccaaga aagaacgtgt gcattgagtc
     5281 gctaggccat atccaactat ttcaaaaggc tttcgtagga aggaagatga gtttttctat
     5341 aacaaggacg caggtctctt tgtttgtcca gaagggcata tggcactaaa gaaggaaaag
     5401 acaggaagaa ggacggctca ggaaacccac tattttgaca tcaagcactg tcaaatatgc
     5461 ccttcaaaag tgggctgtta taaagaaggg gctaagtcta agacttattt gatacccctt
     5521 aagagcgatg aacatatttt ccagaagagg tttcaggaag cgccctattt taaagaaaag
     5581 gccaaacatc gctacaagat agaagccaaa aatgcggaac ttgaaaacag acatggtctt
     5641 aatgtagcta gagcaccagg tcttttaaac atggagttac aagccgccac aaccatattt
     5701 gtggttaata tgaagaggat tataactcta ataaaccaaa aataaggaaa agcaaagagg
     5761 aatctatcca agcaggagat agatccctct tttttcattt tagttgaact gtagagctta
     5821 ctttttcagt ggactcgatg attagtgact atttttttca aactctatta gttattggta
     5881 ccctaatgcc gaatggagat atttaggatt gtaatagatt tcaatatatt taaagatttc
     5941 gttcaatagt tgcgaaattg gcatcattga caagttctct ttttatgttt tgtaaaagga
     6001 ttccatgggt gcattatcat atggattgcc ttttcgactc aggctagact tgcatctttt
     6061 ctgtttaagg agttcttgaa atctagctcc agtatattga gatccttgat cggtatggcc
     6121 gactagttct tatttgagat tttctctatg ataagcttga ttgaaaacat tcgttaccaa
     6181 cttatcttgc attcgatttc ccattgccta accaacaatt tttctgctat aaacatatat
     6241 ataatgataa ataaagagta cctgcttttg tcggaatata agttaaatcc cccagccaga
     6301 tttcattttt accttttgtt tgaaaacact gattaatcaa attgggtcgt gttaatgagg
     6361 aatgccgacg gctatagtac ttgtatttat agcggattcc tttagcatag agacaaa
//
LOCUS       DAVLBN010000089         5953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLBN010000089 DAVLBN010000000
VERSION     DAVLBN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.089"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            67..309
                     /locus_tag="VXC24_002015"
     CDS             67..309
                     /locus_tag="VXC24_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0494073.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            311..565
                     /locus_tag="VXC24_002016"
     CDS             311..565
                     /locus_tag="VXC24_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0494074.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            612..1264
                     /locus_tag="VXC24_002017"
                     /pseudo
     CDS             612..1264
                     /locus_tag="VXC24_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1524..2510)
                     /locus_tag="VXC24_002018"
     CDS             complement(1524..2510)
                     /locus_tag="VXC24_002018"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0494075.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2704..5172
                     /gene="gyrA"
                     /locus_tag="VXC24_002019"
     CDS             2704..5172
                     /gene="gyrA"
                     /locus_tag="VXC24_002019"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0494076.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5172..5915
                     /gene="srtA"
                     /locus_tag="VXC24_002020"
     CDS             5172..5915
                     /gene="srtA"
                     /locus_tag="VXC24_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0494077.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         1872 a          979 c         1296 g         1806 t
ORIGIN      
        1 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
       61 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
      121 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
      181 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
      241 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
      301 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
      361 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
      421 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
      481 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
      541 tggtcattgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
      601 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgatata acaattattt
      661 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
      721 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
      781 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
      841 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
      901 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
      961 caggtaaatt agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     1021 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     1081 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     1141 atattgttcc agtttccctt tttgggaaga cgaattatcg agccaaagaa tattaataga
     1201 gaaacaatcc gagaagatag aagaactgca tcggatgata caagatttgc ttgaaaaaac
     1261 ataataaaaa taaagatgag acaaagtttg agttgaggag aaatcaagta agttttgaca
     1321 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaatga
     1381 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     1441 atggggggct atttcaactt caacctacta taatacagaa aaaaacaact ccctgataat
     1501 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tgggtttttc
     1561 catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     1621 gcgtcgttca atgggatatt tactggacga acaataccat gtgcaccaac aacagctggt
     1681 tgaccgataa agacgttctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     1741 actgcatttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     1801 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     1861 aattcaatca attcagcttc ttgaacattt tgagtatctt taaggaattc ttcaaggttt
     1921 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     1981 atgtaggcgt gaactgaacg agcatctacg tccaattttt cagcaagtgc ttgacggaaa
     2041 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     2101 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     2161 aaacctgatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     2221 aggtcaagac gagtttcacc tggtttttga ggcgcacctg cagtgatcac aacaaggtca
     2281 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     2341 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     2401 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     2461 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     2521 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     2581 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     2641 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     2701 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     2761 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     2821 aaacctgttc accgtcgcat tctttacgga atgaatgaat tgggtgtgac cccagacaaa
     2881 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     2941 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     3001 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     3061 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     3121 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     3181 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     3241 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     3301 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     3361 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     3421 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
     3481 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     3541 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     3601 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     3661 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     3721 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     3781 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     3841 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     3901 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     3961 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     4021 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     4081 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     4141 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     4201 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     4261 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     4321 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     4381 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     4441 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     4501 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     4561 gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     4621 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     4681 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     4741 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     4801 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     4861 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     4921 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     4981 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     5041 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     5101 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     5161 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     5221 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     5281 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     5341 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     5401 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     5461 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     5521 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     5581 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     5641 tagataatgc taaaaatggc atgaagattt atctaactga taaaaataaa gtttatactt
     5701 atgaaatacg tgaagtcaaa cgtgtgacac cagatcgtgt tgatgaagtt gatgatagag
     5761 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
     5821 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
     5881 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
     5941 cactgatttt tta
//
LOCUS       DAVLBN010000090         5939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLBN010000090 DAVLBN010000000
VERSION     DAVLBN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.090"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            411..632
                     /locus_tag="VXC24_002021"
                     /pseudo
     CDS             411..632
                     /locus_tag="VXC24_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(919..1401)
                     /locus_tag="VXC24_002022"
     CDS             complement(919..1401)
                     /locus_tag="VXC24_002022"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0494078.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(1496..2980)
                     /locus_tag="VXC24_002023"
     CDS             complement(1496..2980)
                     /locus_tag="VXC24_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0494079.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3133..4740
                     /locus_tag="VXC24_002024"
     CDS             3133..4740
                     /locus_tag="VXC24_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0494080.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVDPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            4905..5072
                     /locus_tag="VXC24_002025"
     CDS             4905..5072
                     /locus_tag="VXC24_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0494081.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(5065..5586)
                     /locus_tag="VXC24_002026"
                     /pseudo
     CDS             complement(5065..5586)
                     /locus_tag="VXC24_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1751 a         1117 c         1323 g         1748 t
ORIGIN      
        1 aactggttcc ttttgaggta cgacgggcat gtcgtatagt aggttgaaac tagaatagta
       61 cacatctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg atttgtcctg
      121 ttcttatttc attttactat atatctgagg tgtaagtcct cggtgggcac ctgttaccgg
      181 tgaacccaat agcgattccc aagcctgact atcgtgaggt agcggattaa aacggtctgg
      241 ggatagaccg ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa
      301 ctcgtggctc tacgaacagg aacgtgatag taaggcgtat atagcggata agggggcctc
      361 aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg taaatcacga gagcaactga
      421 atttgtccat tcgaggatgg ataaactatt tttcattggg aaatatgaaa agtatagtca
      481 ccagcataga tgagcgtttg catactcgcc tacgagtgat tatctggaag caatggaaga
      541 agaaatcgag acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata
      601 aggtatctgg ctggggcgac cactatcaat tatagtaaaa tgaaataaga atagaacaaa
      661 tcgatcagga tagtcaaatc gatttctaac aatgttttag aagcagaggt gaactattct
      721 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
      781 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
      841 aaagttagtt gaaccgccgt atgccgaacg gtacgtacgg tggtgtgaga ggggctagag
      901 attatcccct actcgatttt aaatcacatg acgttcaaag gcatcatctg aaatcccttg
      961 ttccaagatg agttttgccc attctttagc agagaagagg ctgtggtcct tgtagtttcc
     1021 gcaagattcg atggttgtcc ctgggacatc ttcccaagta gtagtttcag cgatttcctt
     1081 gagcgaatcc ttgataacag ctgcgatttt agcactggtg tgacgtcccc acataatcat
     1141 gtggaagcct gtgcggcaac caaatggtga acagtcaatc atgccgtcaa tgcgggtacg
     1201 gatgagtttg gctaagaggt gctcgatagt gtgaaggccg gcagtaggga tagagtcttc
     1261 gtttggttgc accaagcgaa tatcataatt ggagatgatg tctccttttg gtcctgtttc
     1321 ttccccaatc aagcgaacat agggtgcttt gacaatggtg tggtcaagtt caaaactttc
     1381 gacaataact tcttttgaca tggtaaatcc tttcagtttt cttctctcat tatatcataa
     1441 aggttgctcc tgagacagag agaaaacctc tccgaggctg gagaggttga aatctttact
     1501 tacgatataa gcggtcgtat tggtagtatg ggtcaaaggt tacgttgata cccagtttac
     1561 gaaggacatt cttgtcttca tcagtcaaga tgatggttga gtgggcttcg cttcctttga
     1621 ggttgccgag ttcttccata gcgcgggcag catcaggatt ttctgtagct gtgatagcaa
     1681 gtgcaatcag gatttcattt gaatgaaggc gtggattgcg gctaccgaga tgatcgattt
     1741 taagaccttg gattggctta acaacttcag gctcgattag ttttacttct ttagcgatgt
     1801 cagctgattt tttgatggcg ttgatcaagg cagcggctgt aggcccaaag agttctgagt
     1861 tcttaccagt gacgatttcc ccatttggca attcaaaggc tagggctggt ccaccagttt
     1921 cttctgcttt ttggcgcgca acgacagcaa ccttacggtc tgcaggtgtg ataccgaggt
     1981 cgttcatgag caactcaatt ttcttgacgg cagcttcgcc aactttttca gctttgaagt
     2041 caagaactgt ttgatagtaa cggcggatga tttcttgttt agaagcttcg acagcagcct
     2101 cgtcatctgt aatagcgaaa ccaaccatgt tgacacccat atctgtcggt gaagcgtatg
     2161 gtgattttcc gagaatacgt tccaacatgc gcttgagcac tgggaagatt tcgatatcac
     2221 ggttgtagtt gacagtggtt tctccatagg tttgaagatg gaaggggtca atcatgttga
     2281 catcatcaag gtcagctgtg gcagcttcat aagccaagtt aactggatga tgaaggggaa
     2341 gattccaaac agggaaggtt tcaaatttag cgtagccaga cttgatgcca ttgatttggt
     2401 cgtggtacat attggacata cacgttgcca attttccaga accgggtcca ggagcggtta
     2461 cgacaatcaa gttgcgactg gttttgatgt agtcgttttt gcccatgcct tctggggaaa
     2521 tgatgtgatc catatccgtc ggatatcctt tgattggata atgaagataa gaatcaattc
     2581 cgtttttctc aagttggttg cggaaggcat ctgcagcgag ttggccagcg tattgtgtaa
     2641 tgacaacgga accaacaaaa atccctaatt cattgaattt gtcaatcaaa cgaagaactt
     2701 cttggtcata agaaatgcct aagtcgccac gtgctttgga atgttcaatg ttgctagcat
     2761 taatggcaat cacaacctca acctgctctt tcaattcttg caagagcttg attttgttgt
     2821 caggttcata accaggaagg acacgagcag cgtggaaatc ttctaacatt ttaccgccaa
     2881 actctaagta gagcttgccg tcaaattggt taatgcgctc taagatgtgg tcgcgttgta
     2941 aattcaaata ctgttcagaa ctaaaagctt gttttttcat ttttttacct ctggattcta
     3001 ttataataaa aaattggaag ttaggaaact acggagctaa aaaagaaatt aaaaagatta
     3061 agcaaacgct tgcacaaaat tttaaaaagt gctatcatat actatagatt attaaaataa
     3121 tgaggtaaac agatgcaaga aaaatggtgg cataatgccg tagtctatca agtctatcca
     3181 aagagtttta tggatagtaa tggagatgga gttggtgatt tgccaggtat taccagtaag
     3241 ttggactatc tagctaagct aggaatcaca gcgatttggc tttctcccgt ttatgacagc
     3301 cctatggatg ataatggcta tgatattgct gattatcaag cgattgcggc tatttttgga
     3361 accatggagg acatggatga actgattgca gaagctaaga agcgtgatat ccgtatcatc
     3421 atggacttgg tggtcaatca tacctcggat gagcatgcct ggtttgtaga ggcctgtgaa
     3481 aatcctaata gccctgagcg agactactat atctggcggg atgagcctaa cgatttagat
     3541 tctatcttta gtgggtctgc ttgggaatac gatgaaaagt caggtcaata ctatctccac
     3601 tttttcagca agaaacagcc ggatctcaac tgggaaaatg aaaaacttcg ccagaaaatt
     3661 tatgagatga tgaacttctg gattgataag ggtattggtg gtttccgtat ggatgttatt
     3721 gacatgattg gcaaaattcc tgacgagaag gtagtcaata atggtcctat gctccatccc
     3781 tatctcaagg aaatgaatca ggcgaccttt ggagataagg atctcttgac agtaggggag
     3841 acttggggag caacgccaga gattgccaaa ctctactctg atccaaaggg gcaagaattg
     3901 tctatggtct tccagtttga acatatcggt cttcagtatc aggaaggtca acctaaatgg
     3961 cactatcaaa aagagctgaa tatcgctaag ttaaaagaaa tcttcaacaa atggcagaca
     4021 gagttaggag ttgaggacgg ctggaattcc ctcttctgga acaaccatga cctccctcgt
     4081 attgtctcaa tctggggaaa tgaccaagaa taccgcgaaa aatctgccaa agcctttgca
     4141 atcttacttc atctcatgag aggaactcct tatatctacc aaggtgagga gattgggatg
     4201 accaactatc cgtttgaaac actggatcaa gtagaagata ttgaatctct caactatgcg
     4261 cgtgaggctc ttgaaaaagg tgttccgatt gaagaaatca tggacagtat ccgtgttatt
     4321 ggacgtgaca atgcccgtac ccctatgcaa tgggacgaga gcaaaaacgc tggtttctca
     4381 acaggtcaac cttggttggc agttgatcca aattacgaga tgatcaacgt ccaagaagcg
     4441 ctggcaaatc cagattctat tttctatacc tatcagaaac tggtccaaat tcgcaaggag
     4501 aatagctggc taattcgagc tgactttgaa ttgcttgata cggctgataa ggtctttgct
     4561 tatatacgta aggatggcga ccgtcgcttc ctagttgtgg ctaacttgtc caatgaagag
     4621 caagacttga cagtagaagg aaaagtcaaa tctgtcttga ttgaaaacac cctagctcaa
     4681 gaagtctttg aaaaacaaat cttagttcca tgggatgctt tctgtgtgga attactataa
     4741 atattttttg cagaaaaatt taaaattgaa atcgtataaa aacaagggag gactgtataa
     4801 aaggcagaaa tcctttgttt tttataacca aggtttataa accttcattc tcgaaattca
     4861 attaacttta caaattccca ctattaagga gaaagaagac gaacataaag aagcgtatcc
     4921 ttagtgcagg cctgactttt acatctgctt tgcttttagc tgcttgcgac caatcaggtt
     4981 cagatacaaa aacttactca tcaaccttta gtggaaatcc aactacattt aactatctat
     5041 tagactatta cgctgataat atagtcaatt gaaacaagaa caagacaaaa gagcctcata
     5101 aaaggtattg caacttggta ataccttttt gaggtgcttt ttgatatgag cccatgtttt
     5161 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat gcccaaactc
     5221 ttcgcataaa agttctagct tccccattct atggaatctt gcattatcca taataataac
     5281 cgatggtgtg gttaatgttg gtaagaaaaa cttctgaaac catacttcaa aaaagtcgct
     5341 cgtcatcatc tcttcgtaag tcattggagc gattaattca ccatttgtta gacctgcaac
     5401 caaagaaatc ctctgatatc ttcttccaga tactttgcct cttcttaact gaccttttaa
     5461 tgagcgacca tattctcgat aaaaataagt atcgaatcct gtttcatcaa tctaaacagg
     5521 tgctaggtgc tttaaactat taaaattctt aagaaataag gctacttttt ctgggtcttg
     5581 ttcataatta gattgaaact agagtagtag acctctgctt ctaaaacatt gttagaaatc
     5641 gatttgactg tcctgatcga tttgtcatgt tcttatttca ttttactata tttttgtttc
     5701 gcgggaagtc tactaagata cttaaagatg cagatagtaa aaaaaatgtg tcaatcgaaa
     5761 gtgattatgt ccccaaaaaa tggagagttt gagggcaatt attttgattt catttgacac
     5821 gaggaaccct tgaagctgtt ttgttagcta aaccaaggct agtcttagcc ttggctcgcc
     5881 agcctaacag ctccaagcct cttatcaaat gaaatacttg tcttacactc ctcactttc
//
LOCUS       DAVLBN010000091         5495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLBN010000091 DAVLBN010000000
VERSION     DAVLBN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.091"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1723
                     /gene="lanM"
                     /locus_tag="VXC24_002027"
     CDS             <1..1723
                     /gene="lanM"
                     /locus_tag="VXC24_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV0494082.1"
                     /translation="YTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKHPQRINFKKDFSR
                     ILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPWIVKPLVLEINSL
                     REKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILS
                     NLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNS
                     LNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKNLPEYYYNFGVLLAF
                     IYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLP
                     TEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRD
                     GDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASV
                     LSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEI
                     YDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNLS
                     NRKKTPK"
     gene            1773..2783
                     /locus_tag="VXC24_002028"
     CDS             1773..2783
                     /locus_tag="VXC24_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEV0494083.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            3133..3837
                     /locus_tag="VXC24_002029"
     CDS             3133..3837
                     /locus_tag="VXC24_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEV0494084.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            3818..4747
                     /locus_tag="VXC24_002030"
     CDS             3818..4747
                     /locus_tag="VXC24_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEV0494085.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            4744..>5495
                     /locus_tag="VXC24_002031"
     CDS             4744..>5495
                     /locus_tag="VXC24_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV0494086.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGD"
BASE COUNT         1976 a          649 c          938 g         1932 t
ORIGIN      
        1 ttataccgag gaacagataa gactatattc agaatatgcc aaaaattcgg aatggtataa
       61 atttgcggag ggttcatttg aaatatttag aaaacatccc caaagaatta attttaagaa
      121 agatttttct agaattttgg aaccctttat tattaatttg cttaaattaa tcaataatta
      181 tctagagaat aaagaatacg agtggattga caagaatgga aatatttttt cctctctagt
      241 attttattta gaagatttaa tctatccttg gattgttaaa cctttggttt tagagataaa
      301 ttcattgcgt gaaaaaggtt tacttgaagg ggaatcggag cagcaacggt acaaatattt
      361 tataacattg tttgacaagg aagagaatat attaaatttt tataacaaat atcccgtttt
      421 actgaggcaa atatcggagt cttgtcttcg gttctatact tattttatag aaattttatc
      481 aaatttagaa aatgatttta gtgtgctaga agaagaatta gggctaaggg ggaaattaaa
      541 tgatataaaa tttggaaagg gtgatacaca cagccaagga aaaactgttt tgatactctt
      601 ctttgatgac gcgaaaattg tttacaagcc taaaaattta ataatcaata actcactaaa
      661 tactattgct gagtatatcc gaaaggttga tgaaaaaatt aggataagaa tacctcgaac
      721 tattgcttat tcggatcaca gctatgaaga atttattgat tatctacctc tagagcaaaa
      781 gaaaaattta cctgaatatt attataattt tggtgtgctt ttagcattta tatatttatt
      841 taatgggagt gatatacatt ttgaaaattt aatttcctat ggagatatgc ctgtaataat
      901 agactttgaa acaatgttac agcaacctct atttgatgat aaaactggtc agagtttgct
      961 ggataccctg tttcacaggg tgactcgaac tttgcttctt ccaacagagg gagtaaaaag
     1021 ggaggatggt cttgatgttg agatgagtgc tcttacagga aattttaaga aggatgcttt
     1081 taatggtcaa gttttaatta atttaaatac tgataaggta aagtttgata ttgggaaaat
     1141 tgattttgaa ggtgggaaaa acctgcctgt tcgggatggt gatatagaat ttgataagta
     1201 tataaaagat ttcaaaaaag gttttaggga tttttatctg atatttgaag agttaaataa
     1261 aacagaagaa tttaaaatgc tattaaaagc aaacttgtat ggtttaaaga caagggtact
     1321 ttttagagac acaaatagct atgcttcagt actatctttt ttatatcatc ctgattttta
     1381 tgaagaaatg ttagatagag aaaaagcatt ggaaaatctc tggagcaata agttttctaa
     1441 tcaaggtatt gtagcaagcg aatgtgaaca aatgaggtta ttagatattc cgatttttta
     1501 tacagataca aatatcaatg aaatctacga tgattttgga aatcatttta tttccctaca
     1561 tcaattttct ggatatgact attttatgaa atatttacct aataataatt tggaaaattt
     1621 agaaaagcaa cttgatatca ttgaaattta ttttccaagc tttgatcagc gaaaaaaagg
     1681 atataaatta aacttatcta atagaaaaaa aactcccaaa tgaaagttta gttactattc
     1741 tgcataatga agtagaaaat attgcagact ctttggttat taataatatt tatgacgaat
     1801 atccaatttg gagtatacct gttaatttta aaggttctaa atggtgtctt gaacaaacgg
     1861 gtaatgatat gtataggggt agagctggaa tattactgtt tatgtactat gtaaaattat
     1921 tgaaagataa atcatcatat actcaactgt acaataaaat gttatctgca attccgccat
     1981 ctgtttcttt atctaagacc acatttggtt taactgggga tataggatat ttcattgttc
     2041 tatccattat agaggattac gatacaaata ctctcgcatg cttaaattat ataaagagtg
     2101 ttttaactga gcttgaaaag actgattttg caagtgtttc aaacaagtct gactatatta
     2161 atggtcttct acctttaatt aatacactgg taagatatta taggagagga atagagaagg
     2221 aacgtgttct aaggctagta ttaagtttag gtgatacgct atataatgat gtaagcgaga
     2281 gagataatag taattttgga tatagttttg gccatggact atcaggtgta atttttacat
     2341 taaaaaatat ttataaagtg acaagactta aaaaatataa agaattaatt ttacaactag
     2401 ttcctaggga gaaaatcaaa attcattctt tgaagtggtg tagtggagaa tttgggacat
     2461 tagttaatca tccccaaagt gttccagagg gaattgtagc tagtttagat aatgatacat
     2521 tttgccatgg aagtatggcc ataataaatt tttacatcga ctacatgaaa gaaatggata
     2581 ctagtatgga attggagtct ttattgtgta gtgttgtaat gaataaatca aaagaaggag
     2641 agtatcgtat cgtccaaaca agcaatttcc cagatttttc tttgtataca ggtgtgactg
     2701 gtattgctta tactttttta aggtatatcg cactgaatca gaatgacaaa aagatagtta
     2761 tcccctcatt acttgaaatc tagcttaatt tatagttttg tttctaaaat agaggtgtcc
     2821 actcattaag caatataaaa ataccaagat tgactagttt aatatgtaat tctataaaat
     2881 atttttaata gtgtagcttt tcattgagat aataatataa taaagaaaag ttctattcta
     2941 attgctaaac ggcttgaggt atatgctact gttatagaaa tgattttaaa ctaaaatcaa
     3001 aattactcca aaaatagtat tgattttggt ttaatacaaa acatatgtaa taatgtgagt
     3061 caacaaaagt ctgtttttgt accatactat cttgaaaaat ctactaaatt caaattgaga
     3121 ggatgaatta aaatgaataa aatatttata tatgcaggag tgcgaaatca taactctaag
     3181 actttagagt atactaagag actttcaagt atcatttcta gtagaaataa tgttgatata
     3241 tctttcagga cacctttcaa ttcagagcta gaaatatcta attctgattc agaagagttg
     3301 tttaagaaag gaattgatag gcaaagtaat gctgatgatg gaggtgttat aaaaaaagag
     3361 ttattagagt ctgatattat aattatctct tctcctgtat atttacaaaa cgtatctgtg
     3421 gacacaaaaa actttattga aaggattggg gggtggagcc atctttttcg attagctgga
     3481 aagtttgttg taacattaga tgttgctgag agtaacggct ctgataatgt gtcagaatat
     3541 cttagagata tattttcata tatgggagga cagatattac accaagtttc aattaccaat
     3601 tcactcaaag atattgcaga ggctcagttg atggaggcaa cttataaaat tgaagatgta
     3661 cttgaaggga aaattaagta caaaacaacg gattatcaag aaagagctta ccagacatta
     3721 aaattaattt tagaaaatta tgattccgaa cattttgaga agatgtattg ggagaaaaaa
     3781 cgcctttttg aagctaatag tttagaggaa tggtattatg ttgaaaatat taaataactc
     3841 tgtcatatat ttatgtttga ttccgttatt gttcctatta ttgataattt ttccaaatga
     3901 ttcattaatc tattattttc gattgatttt aatttcgtta atatcaatta cattacatga
     3961 actaggtcat tttttagtgg gaagatgttt atcttataaa ctagagatgc ttgctactcc
     4021 ctttttcttc tatttcagaa aaaaaatata tttcaaattt ccagtgttat tagcattcgg
     4081 ttattgtcaa atgagtaata gaaacattac taatgaaaaa aatagtgata ggaatttggt
     4141 gttctacttc tttgggggag gtggagctaa cctaattgtc gcaatattag cacttttggg
     4201 atttgtgccg tacgcatcag aattttttat tttgaatata attctttttc tagttacggt
     4261 atgtttacca attgatggaa cagatggcaa tgctattaga gagatagttt tgtattcaaa
     4321 agattcaaaa acatatcaga gattctttgc gaacagtctc tataataatc cttatataac
     4381 aatcgacgat tttgcaaaat taacctctaa agaaaaatct tttttttcaa aatttgaaaa
     4441 atgtttgata aacctttact ttgaagtgaa aggtgaaggg tcagcattta caattgctaa
     4501 tcatgaagtt tttgattcaa atattcagga aaatattatc catgagtact ataaattact
     4561 acataaatct tctgattgga ttattccaca gaacttatct ttagaagaag ttgtttttac
     4621 cttgtcaaac tatatttact cgaaaaataa taaatattta gaaaagatta agtatctaaa
     4681 gaaattagta gattttagac aagaagaaat tatcgacttt attttgaaca aggaggaagt
     4741 attgtgaaaa ttccaatgat atatcaaatg gaaaattcag aatgtggatt agcatgctgt
     4801 gccatgatat tgaactattt taaatatgag atttctttaa atgaactacg tgaaatctac
     4861 ccatcatcca gatctggata ttctctccta tctataagta aagttttagg agattttaat
     4921 ataagttctc atgcttttaa agcttcggta agagatttaa aaccgctcag tttcccactc
     4981 atttgcttct gggagagttc tcattttatt attcttgaaa aaattagtaa aaacaagttt
     5041 tatattttag atcctgcaaa aggcaggcag agaatgtcaa taagtgaatt tgaaaggcat
     5101 tattcaaata tcattttaac atttaaaaag ttagatagct ttatgtctcg taaagataat
     5161 aagaagtcgc ctgttttaaa gtattttttt aagtatagga ataagctagg gattttattt
     5221 tttgtaacag cattattgta tgtaatacaa tcattagtac ctatagctaa tagatacata
     5281 attgacacga atttcaagga cgattcgtat tcgtctagaa tgttatttac tatattattt
     5341 atatttactg tttcattctc actaatgtat ttattaagac agatatatgt tgcatcctta
     5401 aaatatataa tggataaaga gattagctat gattttatga aacatttgat atatttacct
     5461 tacagttttt atgaaaaacg tactttaggg gatat
//
LOCUS       DAVLBN010000092         5343 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLBN010000092 DAVLBN010000000
VERSION     DAVLBN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5343
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.092"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..738
                     /locus_tag="VXC24_002032"
     CDS             <1..738
                     /locus_tag="VXC24_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0494087.1"
                     /translation="RVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAI
                     VGESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGT
                     LRENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLA
                     RCLLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMH
                     NGEIVEIGTHRELLELGGIYKQLYSNN"
     gene            762..2500
                     /locus_tag="VXC24_002033"
                     /pseudo
     CDS             762..2500
                     /locus_tag="VXC24_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            2551..3318
                     /locus_tag="VXC24_002034"
     CDS             2551..3318
                     /locus_tag="VXC24_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0494088.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            3320..3952
                     /locus_tag="VXC24_002035"
     CDS             3320..3952
                     /locus_tag="VXC24_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494089.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4898..5311)
                     /gene="ndk"
                     /locus_tag="VXC24_002036"
     CDS             complement(4898..5311)
                     /gene="ndk"
                     /locus_tag="VXC24_002036"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0494090.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
BASE COUNT         1856 a          793 c         1007 g         1687 t
ORIGIN      
        1 agagtcagtc aagatataaa atttgataaa aaaatagaat taaaagatat ttggtataaa
       61 tatggattat ttgatgatta tgttttgaaa ggaataaatg ttactattaa aaaaggagaa
      121 actgttgcta ttgttggaga atcaggttca ggtaagagta cattagctaa aattttatta
      181 ggtttattag aacctaatat tggttcaata gaagttgatg gagtagaaaa agaagaaatt
      241 ggtcaaacat tgtatagaaa gatttttgga gcagtgttac aaaattcaac cctaagttat
      301 ggtaccttaa gagagaattt gacatttgga cactttgttt cagatgaaga attaatgaca
      361 aatctaaatt caattggtct tagcaatgta gttaaatctt tacctcttgg attagagaca
      421 atcatcgctg aagaaggtaa taacttttct ggagggcagc agcaaatgat acttttagct
      481 cgttgtcttt tgtcgaaacc ttcggtagtt gttttggacg aagcaacaag tagtttagat
      541 aatttatctc aacaaattac aacttcttac ttaagtgaaa tcggtaccac taagatttta
      601 attgcccatc gactagatac tatcaagtct gcagataaga tcttagtaat gcataatggt
      661 gaaattgtag agattgggac ccatagagaa cttcttgaac taggaggcat ttataagcaa
      721 ttgtattcaa ataattagtt tttgattaaa agggtaaatt tatgaagatt atgaaaaaaa
      781 aatattggac tttagcgata ttattctttt gtttgttcaa taattctgtt actgctcaag
      841 aaatacctaa aaatcttgat ggcaatataa ctcacactca gactagcgaa agtttttctg
      901 aatctgatga aaaacaggtt gactattcta ataaaaatca agaagaagta gaccaaaata
      961 aatttcgtat tcaaatcgat aagacagaat tatttgtaac aacagataaa catttagaaa
     1021 aaaactgttg taaattggaa cttgaaccac aaataaataa cgatattgtt aactctgaaa
     1081 gtaataattt actaggcgaa gataatttag ataataaaat taaggaaaat gtttctcatc
     1141 tagataatag aggaggaaat atagagcatg acaaagataa cttagaatcg tcgattgtaa
     1201 gaaaatatga atgggatata gataaagtta ctggtggagg cgaaagttat aaattatatt
     1261 ctaaaagtaa ttctaaagtt tcaattgcta ttttagattc aggagtcgat ttacaaaata
     1321 ctggattact gaaaaatctt tcaaatcact caaaaaacta tgtccccaat aaaggatatt
     1381 taggaaaaga ggagggagag gaaggaataa tatcagatat tcaagataga ttaggtcatg
     1441 gtacggctgt tgtagctcaa attgtagggg atgacaatat taatggagta aatcctcacg
     1501 ttaatattaa cgtctataga atatttggta agtcgtcagc tagtccagat tggattgtaa
     1561 aagcaatttt tgatgctgta gatgatggca atgatattat caatcttagt actggacaat
     1621 atttaatgat tgatggagaa tatgaggacg gaacaaatga ttttgaaaca tttttgaagt
     1681 ataaaaaggc tattgattac gcgaatcaaa aaggagtaat tatagtagct gcattaggga
     1741 atgactccct aaatgtatca aatcagtcag atttattgaa acttattagt tcacgcaaaa
     1801 aagtaagaaa accaggatta gtagttgatg ttccaagtta tttctcatct acaatttcgg
     1861 tcggaggcat agatcgctta ggtaatttat cagattttag caataaaggg gattctgatg
     1921 caatatatgc gcctgcaggc tcaacattat ctctttcaga attaggactt aataacttta
     1981 ttaatgcaga aaaatataaa gaagattgga ttttttcggc aacactagga ggatatacgt
     2041 atctttatgg aaactcattt gctgctccta aagtttctgg tgcgattgca atgattattg
     2101 ataaatacaa attaaaagat cagccctata attatatgtt tgtaaaaaaa ttctggaaga
     2161 aacattacca gtaaaaaatg gtataaaagt gttaaatata ccaaacgtat tgagatatga
     2221 tttgaatatg ttacaattag aatataaaaa tgaacaaagt tgggatagtt tcatagataa
     2281 tgttaattta attgagttgg aagagagaat tcaaactact attggaatta aacaaataaa
     2341 cacacacaat attattacta ttgcccgaga agggtactct caaaattatt tacctaacac
     2401 ttcagaaaat acatataatt cattacaagt cagtttagtt ggagtattac tactttttat
     2461 aagtatggta aatattttat gggctaaaaa aagtaaatga aaataaaatt tggagccctc
     2521 tgaaaaagta agtcctacag ttcaactaaa atgagtcaaa agatgaatca ccttgatgta
     2581 ggggagtttg tcttattgct gcctgaacac ctccgttcag aggaagaaca ttataaatct
     2641 gtttttgaag acgacttaac cagtcgcata tctagtcaag atgaacgaca gcaaatgact
     2701 gctacggtag gttatttaga atcaggtcag gatcgttttg tgtataatac gacccctatt
     2761 tcttaccagc agtttttgaa agatccaatc atcattgtta taacacccca atcaactggt
     2821 ccacagtcca ttttgttttg gatagacgca gtacagaact acgttctctt taatcaattg
     2881 tctgatgccc aggagcttat ccagagacaa ggcattgaaa attgggtctc agaaatgcaa
     2941 acaggttacc acaactacat cacattattg gataatatcc agagggaacg ttgggtaatg
     3001 ctagcaggag ctgtgcttgg gattgcaact tcaatcttgt tgtttaacac tatgaatagg
     3061 ctctactttg aagaatttag acgtgccatt tttatcaaac gcattgcagg tctcaggttc
     3121 ttagaaatcc atcgcactta tctctttgct caactgggtg tgtttttact gggatttgtt
     3181 gcgagtgtat ttcttcaggt agagatagga gttgctttct tagtcttgtt actctttact
     3241 ggtctatctc ttttacagtt acatgtccaa atgcagaaag aaaacaagat gtccatgctt
     3301 gttttgaagg gaggttaata tgattgaact taaacaggtg agtaaatctt ttggagaacg
     3361 agagttattt tcgaatcttt caatgacatt tgaggctgga aaagtctatg ccttaattgg
     3421 ttcaagtggt agcggaaaaa caaccttgat gaacatgatt gggaaattag aaccttatga
     3481 tgggacgatt ttttaccgag gtaaagactt ggccaattat aaatcaagtg attttttccg
     3541 tcacgaattg ggctacctct tccagaactt tggcttaatt gaaaaccaaa gtattgaaga
     3601 aaaccttaag ctaggtctca ttggtcaaaa gttgagtcgg tcggaacagc ggttgaggca
     3661 gaagcaggct ttagaacagg tcggcctggt ttatcttgac ctagataagc gcatctttga
     3721 gttatcgggc ggagaatcgc aacgggttgc cttggcaaaa attatcttaa agaatccacc
     3781 ctttattctg gcagatgagc caacagcttc aatagaccca gcaacctctc agttgattat
     3841 ggagattttg ctatctcttc gagatgataa taggctaatc attatcgcaa cacataatcc
     3901 ggcaatttgg gagatggctg atgaagtgtt cacgatggat catctgaaat aaaaatcctt
     3961 gtttttaatt gcacgatgag ttactgaaat attatcatga atcaagaatt ggagttaatt
     4021 tagaattgta cttaatttag aattgtactt tattaatatt gaggtaactt tttcttgata
     4081 aaggaagaaa taatggagag gaagttagaa tgaaaaaatt cgacaattat attattgaga
     4141 agccttgcga ttctaattca gataaactgc aaaaaatctt aataattgaa agtttggtag
     4201 atgatatttt gcaattttct ctcagaatca ataatagtgt aggagagatt ttcctcctac
     4261 aaccgtttta aaagaaaact atctttattc catgttattt tgaggaagat attgtgaaag
     4321 tcaaagatga tgataaagtt gagtggaatt tgttagaatt tcaaaaattt agagcatttt
     4381 tggcttagta atctgtgttg aaggctcaaa acctatggta aaaaagtagc tttgaaaacg
     4441 tattgcctcc aaagatttag ttaaataatg atttaacaca aaaagaaatt attgaagttc
     4501 tggaaagatg ttgtttcagt attgagaaaa ggtgggaaaa acttgcgatt ttcacagaga
     4561 aaggaagaaa aagtatagaa atatagtcaa ttgaaacaag aacaggataa aagaaccttt
     4621 tgtgccatat ttttctcctt tcgctttaca attggattga acacctttat tgtatcgcgt
     4681 atggagtttt tttggtataa ccttcgacgc acacccgcat agcgggtgtt ttttttgtct
     4741 cgcacctaac ggagcgagac aaactaatag tcacttaatc aaaaaacgca ccatatcaaa
     4801 aactaaaaag tttgatatca tgcgtcatgt cttaaactaa ttgactatac tttctattca
     4861 aatgagcttt taaccaattg attgagccaa tccactctta aaaccaaaga gcaatttctc
     4921 gcttagctga ctcttctgaa tctgaaccat gtacaacatt ttggataatc tcattttctc
     4981 cagcagcttt tgcaaaatca cctcgaatag tgcctggtaa agcttcttct ggacgagttg
     5041 cacccatcat ggtccgccaa gtttcgatta ctttgggacc agaaatgaca cccacaagaa
     5101 ctggacctga agtcatgaat tcacgaatcg gtgggtaaaa actctgacca accaagtcct
     5161 gatagtgctg gtcaatcaac tcttctgaaa cctgtgaacg aaactccaat ttttcgattg
     5221 taaatccacg ttgttcgatg cgctttaaca cttcacccac tagccctctt tttacaccat
     5281 ctggtttgat gataaagaat gtttgttcca tacccgtctc ctttgtcagc ttctttcttt
     5341 tat
//
LOCUS       DAVLBN010000093         4958 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLBN010000093 DAVLBN010000000
VERSION     DAVLBN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.093"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(121..288)
                     /locus_tag="VXC24_002037"
     CDS             complement(121..288)
                     /locus_tag="VXC24_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494091.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(455..526)
                     /locus_tag="VXC24_002038"
     tRNA            complement(455..526)
                     /locus_tag="VXC24_002038"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(491..493),aa:Arg,seq:cct)
     gene            complement(568..915)
                     /gene="rplS"
                     /locus_tag="VXC24_002039"
     CDS             complement(568..915)
                     /gene="rplS"
                     /locus_tag="VXC24_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0494092.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1034..1363)
                     /gene="crcB"
                     /locus_tag="VXC24_002040"
     CDS             complement(1034..1363)
                     /gene="crcB"
                     /locus_tag="VXC24_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0494093.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1357..1731)
                     /gene="crcB"
                     /locus_tag="VXC24_002041"
     CDS             complement(1357..1731)
                     /gene="crcB"
                     /locus_tag="VXC24_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0494094.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1728..1994)
                     /locus_tag="VXC24_002042"
     CDS             complement(1728..1994)
                     /locus_tag="VXC24_002042"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0494095.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2110..2553)
                     /locus_tag="VXC24_002043"
     CDS             complement(2110..2553)
                     /locus_tag="VXC24_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0494096.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            2657..3592
                     /locus_tag="VXC24_002044"
     CDS             2657..3592
                     /locus_tag="VXC24_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0494097.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3646..3930
                     /locus_tag="VXC24_002045"
     CDS             3646..3930
                     /locus_tag="VXC24_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0494098.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3987..4205)
                     /locus_tag="VXC24_002046"
     CDS             complement(3987..4205)
                     /locus_tag="VXC24_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494099.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(4202..4958)
                     /locus_tag="VXC24_002047"
                     /pseudo
     CDS             complement(4202..4958)
                     /locus_tag="VXC24_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1538 a         1072 c          880 g         1468 t
ORIGIN      
        1 tttgttatta tataggcttt tgttgattta tttcttgttt taattcagtg gaatagtaac
       61 gattcttccc ttttttaacg ctctctgttc aataacgatc aattcacctt gtcacatacc
      121 ttagccagaa acatccatac caaatctttt tgaaagctga ttaaagcttt gtactttctt
      181 tctaagttca tagaactgaa ccttaacgtc atttggcaat tccataataa aaataaggac
      241 attccaataa aggaagtcct ttttagcact actataaatc aaagacattt ttatgatcca
      301 ttttattcta taatcattga ccaaaatata atttttggtc aaaatttggt caaaaaaatt
      361 aaaaatgcta aattattttt aaaaatgaac ttgagaaaat tgccttcaaa taaacatttt
      421 gaattttctt tgtctttctt tacattacta aaaatgcccc ctgcaggaat cgaacctgca
      481 actactcctt aggagggagt tgttatatcc attgaactaa gggagctaga taaaaactct
      541 gctgaaaagc agagtttttt agtcgaatta acgacggatt tctttgatac gagctgcttt
      601 accttgaaga gcacgcaagt agtacaattt cgcacgacgt actttaccgt aacgaacaac
      661 ttcgattttt tcaacacgtg gagtgtggat tgggaagata cgctcaacac ctacaccgtt
      721 agagatttta cgaactgtgt agttttctga gattccagca cctttacgtg cgataacaac
      781 accttcaaaa atctggatac gttcacggtt accttcgaca actttcgcgt gtacacgaac
      841 agtgtcacca ggacggaatg atgggatatc tgtacgaagt tgaccttcag tcaagctttg
      901 gattaatgga ttcattttat tctcctatct ttgtcaatct tgaggaaatt tcctcagcgg
      961 ataaactgta tttttgtgcg tccatcacac acaagataca gtctaccaaa ttttcacaaa
     1021 aaagtaaaga aatttatagc aaaattccta aaaaaatcgc aaccaaacca cctatgtaag
     1081 tcaaagtcag gtaagaataa aagaccttct tatcacttaa cagtctttga agttcgtcat
     1141 tcaaggtcga aaaagttgtt aaaccgccac aaaatcctgt tgctagaata gcatatactt
     1201 ccttagactc tacatgattg tagaatactc caattaaaaa acaacctaaa agattagcta
     1261 tgagcgttcc gagtggcaat ttagaagctt gattgtagcg ggaaaagaaa taccgtacga
     1321 gtgctcccaa gccacaggcg attgcaagat agacgattac catttcttcc tccctagaaa
     1381 ataagctaag agtaggcctc caccgatgct caaaagcaaa tacaggacta aactaagata
     1441 acgccctgta tcaagcagct tcacagtatc aagcattagg ctggaaaaag ttgttaaacc
     1501 tccgcaaaaa cccgtcccca gtgctaaaat caagccctta ctagtcccct tatagaccag
     1561 atagcccttg acaagaaaaa tcaagcagaa aattcccaga tagttgacaa agagagtgcc
     1621 ccaaggaaag tctggactgg ctggtaacca ggtggaaact agatatcgga caagtccgcc
     1681 caacatagca gctagaaaaa ttcctagcgg ataaaattgt tcttttttca tttgatattt
     1741 tgatcctgat aatcacgcga acgtttgagt atgtccgaaa aagtcgctac aatagtctcc
     1801 tgatagcgct tgtcctctac acgactccta accttttcaa aaataacttc ttctctctta
     1861 gtatctaaaa tcggtttacc tgaagctttc ttataagcaa ccaccccctc aactaaatgc
     1921 attcgttctt ctaacagttt gacaatttgg tcatcgattt gatcgatttc ttgacgaata
     1981 atatctaaat ccatacagtc tcctccttta tttgaattat tgtatcaaaa agccatcaat
     2041 taggctagta aaatcccaac tctcgataag aaaaatgcac tgattgatta catcagcgca
     2101 cttttatgct tatactactt tagcaaccaa ttcttctgcg aattgttcca agcgttcaat
     2161 atcttcttcc tcggcagaaa gatcaacttt aacacactct gaaccttttt ctgctcctat
     2221 tgacacaaag acacggtcaa agtcatcaac agccttacag aattcatcgt agaaggtatc
     2281 tcctgagccg accactccgt agattttgcc attcaagttg agatctgcta ggtcttcgta
     2341 gaagtccatc atctcatctg gcaattcacc atcaccataa gtataggtcg caacgatagc
     2401 gatgtctgct tccaagaagt ctgaagcgtc aacagttgta cattcatcaa catcaacatc
     2461 caagcccaag tcacgtaatt tgtctgctac aatatctgca atttcttcgg tattaccggt
     2521 catactggca aatacaattt ttgctaatgc catatcgtcc tcctcaattt atctttctcc
     2581 attatatcac atctttttca ttttaaaaat aaaaattctt gtgctacaat gaaatgagaa
     2641 agaattgagg ttatttatgg agatttgcca acaaatttta gaaaaaatta aagaatacga
     2701 caccattatc attcatcgtc atatgaaacc agaccctgat gccttgggaa gtcaggtggg
     2761 attgaaagcc ttgctggaac atcatttccc agaaaaaacc atcaaagccg tcggttttga
     2821 tgaaccaact cttacttgga tggctgagat ggatcttgtt gaagatagag cctaccaagg
     2881 cgcacttgtc atcgtctgtg atacagctaa tactgctcgt atcgatgata agcgctatag
     2941 tcaaggtgat tttctcatta agattgacca ccatccaaat gatgatgtat acggtgacct
     3001 gtcttgggtc gatactagtt caagtagcgc tagcgagatg attaccctat ttgcccaaac
     3061 aacccaacta gccttggcag atcgcgatgc tgagttgctc tttgcaggaa ttgtcggtga
     3121 tacaggtcgc ttcctctacc cttctaccac tgcacggact cttcgcctgg ctgcttattt
     3181 gagagaacat aactttgact ttgcggctct cactcgcaaa atggacacta tgagctacaa
     3241 aattgctaaa ctgcaaggct acatctacga ccatctggaa gtggatgaaa atggtgctgc
     3301 tcgcgttatc ctgagtcaag aagtcttgaa acaatacaat gtaaccgatg ctgaaactgc
     3361 agccattgtc ggtgcacctg gacgcattga cagagtgagt ctctggggaa tttttgtcga
     3421 acaggctgat ggccactacc gagttcgctt acgcagtaaa atccatccta tcaatgaaat
     3481 cgccaaggag catgatggtg gaggccaccc tctagcaagt ggtgctaatt cctatagcct
     3541 agaagaaaac gaaatcatct accaaaagtt aaaaaacttg cttaaaaact gataaaatac
     3601 ttgccaaact tttcagaatc tgatagacta gtatggtaac aatctatggc tcgcaaagag
     3661 accatggcag aaaggaaata ttgcaaaatg aaaaaagata tccatccaga atatcgccca
     3721 gttgtcttca tggacacaac tactggttac caattcctta gcggttcaac aaaacgctct
     3781 aacgaaacag ttgagttcga aggcgaaact tacccattga tccgtgtgga aatttcatca
     3841 gactcacacc cattctacac tggacgtcaa aagttcactc aagcagatgg acgcgtggat
     3901 cgtttcaaca aaaaatacgg tctcaaataa tgataagaga acagtttcgg ctgttctttt
     3961 ttgtttcttg aaatcaactg ctgttttcat gttccagact catctgtagg tttggtttcc
     4021 atgctactag gcaggaagga aatagctgtt tcaacacgtc cataatgagc tgtactattg
     4081 tcacgaacca cactttcatt gatggtccaa gtggaattca ttttcttaaa agcttctcgg
     4141 actttttcca aatctttgga ggcaatggcc tgctctaagg tttcaaaacg aggacttata
     4201 ctcatctgct ttcacaaagc attctagtcc atctccgatt aacgatgggc tttatcacct
     4261 ccttctccag tccttgtatg atatcttaaa gttgattcat gacatcttcc aaagtttgaa
     4321 aggctttatt tttaaatcca cgtttacgaa tctctttcca cacttgttca atggggttca
     4381 tctctggtgt gtacggagga ataaatgcaa agccaatatt agtcggaatc tttaaggtac
     4441 ttgatttatg ccatatagca ttgtccataa cgagtaaaag ataatcatct ggataagctt
     4501 gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt acatccacca gctcttaaga
     4561 aaaatgattc gcctgtatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat
     4621 agtgactatg gacatgtgga cctactccta ttggagacca acaagatccc agtttactga
     4681 ttctaccgaa accagcctca tcttggtaca tcgagcgaac cttatgaaaa ggtctactgg
     4741 ttttaaagcg ctttcttttc ttcttgaatt gagattttat ttttagacgc gacaatggtt
     4801 tgagcgtctg ctttcttagg atgttctgga cgtggcataa tatttcgcca accatggcgc
     4861 ttcaacagtt gatagaaggc atcacgtgtg taggaacgat ataagcctga aataaggtat
     4921 tgtaacaaat tctcctgcct ctgtagcctt caaatggc
//
LOCUS       DAVLBN010000094         4855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLBN010000094 DAVLBN010000000
VERSION     DAVLBN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.094"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..701
                     /locus_tag="VXC24_002048"
                     /pseudo
     CDS             105..701
                     /locus_tag="VXC24_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            858..1226
                     /locus_tag="VXC24_002049"
     CDS             858..1226
                     /locus_tag="VXC24_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0494100.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            1239..1625
                     /locus_tag="VXC24_002050"
     CDS             1239..1625
                     /locus_tag="VXC24_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494101.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYAD"
     gene            1632..1721
                     /locus_tag="VXC24_002051"
                     /pseudo
     CDS             1632..1721
                     /locus_tag="VXC24_002051"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1707..2330
                     /locus_tag="VXC24_002052"
     CDS             1707..2330
                     /locus_tag="VXC24_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494102.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPTNLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            2320..3965
                     /locus_tag="VXC24_002053"
                     /pseudo
     CDS             2320..3965
                     /locus_tag="VXC24_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4068..4760)
                     /locus_tag="VXC24_002054"
     CDS             complement(4068..4760)
                     /locus_tag="VXC24_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0494103.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
BASE COUNT         1516 a         1040 c          840 g         1459 t
ORIGIN      
        1 gtgtactgtt atagattcaa tacactatag aatagaattg taggttttaa aaacgcttac
       61 attgttttaa aataaactta aataacacaa cggagatatc catcatgaaa aagaaatgga
      121 tgtattatgc tgcttgttct tctaatgaat ctgccgatga cagttcatct gataaaggag
      181 acggtggttc gctagtcgtt tattcaccaa actcagaagg cttaattgga gcaactattc
      241 ctgcctttga agaaaaatat ggtatcaaaa tagaactgat tcaagctggt actggagaac
      301 ttttcaaaaa actagagtca gaaaaagaag ttcctgtagc tgatgttatc tttggtggtt
      361 cttatacaca atatgctacc cacggagaac tctttgaaaa ctatatttca aaagaaaatg
      421 ataatgttat caaagaatat caaaacacaa ctggcttctc tactccttat acactagatg
      481 gtagtgtttt aatcgtccac cctgatttaa ctaaaggcat gaacatcgaa ggatatagcg
      541 accttctcaa acctgaacta aaaggaaaaa tcgcaactgc tgacccagca aactcttcta
      601 gcgcctttgc tcaattaaca aatatgctac aagctcaagg tggttacaaa gatgataagg
      661 cttggtctta tgtaaaagat cttttcacac ttattgatgg tatagtaaaa tgaaataaga
      721 acaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
      781 gtactattct agtttcaata cactataaaa tcggttcaag ttcatctggt gtctataaag
      841 cagtcgttga tggagaaatg gctgttggtc tctcttatga ggatccagca gttaaactct
      901 taaatgacgg agctaacatt aaagtagtct atccaaaaga aggaaccgtc ttcctacctg
      961 ctagtgctgc tatcgttaaa aaagctaaaa atatggaaaa tgccaagaaa tttatcgatt
     1021 ttattatctc tcaagaagta caagatacac ttggtacaac cactactaac cgtcctgttc
     1081 gtaaaaatgc taaaacaagc gaaaacatga aaccaattga caaaatcaaa acactcactg
     1141 aagattatga ttatgtcatc aagaataaat cagatatcgt taagaaatac aacgaagtct
     1201 ttacagatat ccaatctaaa cagtaaaaga ggttcactat gagtgagatc gaaattatta
     1261 acgccaaaaa aatctaccac gatgtccctg ttattgagaa tttgaacatt acaattccaa
     1321 aaggaagtct ctttaccctt cttggagctt caggatgtgg gaaaacgacc cttcttcgta
     1381 tgattgcagg tttcaacagt atcaaagatg gagaatttta cttcgatgat acaaaaatca
     1441 ataatatgga acccagcaaa cgcaatatcg ggctggtttt ccaaaactac gctattttcc
     1501 cacatttgac tgtccgagac aacgttgctt ttggtcttat gcaaaagaag gttccaaaag
     1561 aagaattgat tcaacagacc aacaagtatc ttgaactcat gcaaattgct caatatgcgg
     1621 attgaaagcc cgataaactc agtggtggac aacaacaacg tgtcaccttg gcatgcgcct
     1681 tagcggttaa tccaagtgtt ctcctcatgg acgagccact tagtaatctg gaggccaaac
     1741 ttcgcttgga tatgcgtcaa gccatccgag aaatccaaca cgaagtggga attacaactg
     1801 tttatgtaac ccacgaccaa gaagaagcca tggctatttc agaccaaatt gctgttatga
     1861 aagatggggt gatccaacaa atcggccgac caaaagaact ctatcataaa ccagctaatg
     1921 agtttgtggc aacctttatc ggacgcacaa atattatccc tactaatctt gaaaaacgga
     1981 gcgacggcgc ttatatcgtc ttttcagatg gctatgccct tcgaatgcca gctcttgatc
     2041 aggttgagga gcaagctatt catgtaagca ttcgtcccga agagtttatc aaagatgaat
     2101 ctggagatat tgaaggaact attagcgata gcgtctatct tggactaaat acggagtatt
     2161 tcattgagac aggttttgcc tcaaaaattc aagttagtga agaatcaact tttgaagaag
     2221 aactacaaaa aggcaatcgt attcgtctac gaatcaatac gcaaaaatta aacatctttt
     2281 ctgcagatgg ttcccaaaac ctgataaaag gagtcaacca tggaatgtaa aaaactaaat
     2341 atttggacaa cctcctcttt cttcatcttt cttacctatc ttgtctttct cgtttatcct
     2401 atcgttaccg tgctcaagca agcacttata catgaaggac aattctcact agctaatttt
     2461 gtcactttct ttagtaaagt ctactactct gagacactag tcaacagttt caaggtttcc
     2521 attaccgcta ctgtcacttc cttagttgta ggaaccctat tagcttatct cttctctatg
     2581 tatgacttca aggggaagaa atttctacaa atattgatta tcattgcttc catgtcagct
     2641 cctttcgtag gagcctactc ctgggttctc ttgctaggac gaaatggggt catcactaaa
     2701 tttttgacaa atgcccttca tcttccagct atcgatattt atggattcaa aggaattgta
     2761 cttgtcttta cactgcaact attcccactg gtatttctat atgttgctgg aacaatgaac
     2821 agtattgaca attctctact tgaagcagct gaaagcatgg ggtccttcgg atttaaacct
     2881 atcgtaacgg ttgttttacc tctcctagtt ccaaccttac tagcagctcc ttgcttgtat
     2941 ttatgagagc attctcagac tttggaacgc ctatgttgat tggcgaagga tatcggacct
     3001 tccctgtcct gatttatacc caatttatta gcgaggttgg aggaaattct gcttttgcaa
     3061 ttatggcgat tatcattgtc ttggcaattt tccttatcca aaaacacatt gcaaaccgct
     3121 acagtttcag catgaatctg ctccatccaa ttgagcctaa aaaaactaca aaaggaaaaa
     3181 tagctgccat ttatgcaaca gtctacggaa ttatctttat ctctgtttta cctcaaatct
     3241 acttaattta tacctctttc ctaaaaacat caggtatggt atctgttaaa ggttattctc
     3301 caaacagtta caaggtagct ttcaatcgta tgggatctgc tattttcaat accattcgta
     3361 tccctttgat tgccttagtt ctagttgttc tatttgcgac atttatctcc tacctagccg
     3421 ttagaaaacg gaatttgttt acaaacttaa ttgacagcct cagtatggta ccttatattg
     3481 taccaggaac cgttctaggg attgccttca tttcttcctt caatactggt ctatttggaa
     3541 gtggatttct tatgattaca gggactgctt tcatcttgat tatgtctcta tctgtcagaa
     3601 gattacctta tactattcgc tcatctgttg ctagcttaca acaaatagca ccaagtattg
     3661 aagaagctgc tgaaagctta ggaagtagtc gtctcaatac ctttgctaag attacaactc
     3721 caatgatgct atctggtatc atttctggag ccatcttatc ttaggtcata atgatttcaa
     3781 aactctctac ttctatcctc ctctacaatg tcaaaacaag aacaatgact gtagctattt
     3841 atacagaggt tctcagagga aattacggtg tagccgcagc cttgtcaact atcctgactg
     3901 ttctaacagt aggttccttg ctcttgttta tgaaaatctc taaaagcaat agcattacac
     3961 tttagttttc cacatcaaaa acagccgaaa ggagtaccct cggctgtttt ttcttatctt
     4021 gatattctta tcaaatccct agctcatggc aagcaagtct agactgatta aatagagcct
     4081 tcttccatct tctcacgtcc tagctctcgg taactacggt caccgacaac ttcaacccta
     4141 aactgaccgt cctcatattc aagaatcgtc acgctaccat tatctagacc atgcggatgc
     4201 atgccattaa tcagataaac aatggttcca atagtcattc catggctgac aacaagggcg
     4261 ttacctccac cttgatcttc catttctttt gcaatcattt caaagccttc cttgattcgg
     4321 ccactgagtt tttcccagcc ttcagcccaa ccagctgtat cgacctctac caagccctca
     4381 gccagttcag cataagacaa ttggtgaacg tggtccacat taaagatacg aggaataatg
     4441 cccatgaaaa gatcgccatc ataggctcca tcaaaactac cgaaacacca ttctctgata
     4501 cgcttgtcca tgcgataagg gattttcccc tgcaagccaa gttcttcaag gataattccc
     4561 atggtctgaa tggtacgacc agaatcactc gaataagcgc gctcaaactg tagatcagat
     4621 tctcgcaaac caattcctaa ctcttgaatc cctcgttcac cttcagcagt taagggagta
     4681 tcgctccaac cttgcgcgcg accaatcgtg ttaaacatgg tcttgccatg acgtaccaaa
     4741 tacaatcgta cttttaccat tttccgtcct ccgtttgctt ctattatatc atgaatgata
     4801 aaataaaagc cacccataca ggcgactttt gaaggagatt attatgaaaa agttt
//
LOCUS       DAVLBN010000095         4828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLBN010000095 DAVLBN010000000
VERSION     DAVLBN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.095"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            382..1577
                     /locus_tag="VXC24_002055"
                     /pseudo
     CDS             382..1577
                     /locus_tag="VXC24_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(1956..2741)
                     /locus_tag="VXC24_002056"
     CDS             complement(1956..2741)
                     /locus_tag="VXC24_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0494104.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(2743..3560)
                     /locus_tag="VXC24_002057"
                     /pseudo
     CDS             complement(2743..3560)
                     /locus_tag="VXC24_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            complement(3562..4554)
                     /locus_tag="VXC24_002058"
                     /pseudo
     CDS             complement(3562..4554)
                     /locus_tag="VXC24_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT         1736 a          948 c          791 g         1353 t
ORIGIN      
        1 aagttactaa aaaaagattt tggaataaac tttttcatag cgataaaagc accgtacaag
       61 ctaggaaaat aataagtaat cgcccaatct gaccttctcc agaacttgat tattcgtcta
      121 tcactacagt tgacaaacat actaagatta gtagtgagga aatctccaac gggagagagt
      181 actcattact ttttctttgt gttaaaatag tggtgtcttg ttaagtcata gagctctcta
      241 tggtgctaga cgtcgcttga caaactggca agaaacctgt tttaggaaga attttatcaa
      301 agtatgtggg atactagacg tcgagtattg gaaataaaat cactaaaaca aggagtcatt
      361 caagacaaag gggtaaacat gatgcggaca gttttcagaa tggatgtgag taaggcaagc
      421 tcagaagtcg ctattcttgt gaatggtgaa aaggttcatg gctataccat gcccaatgat
      481 gccatcggat ttagtcgtct tctagaggat ttgaaatagg taaatacacc tgagattatc
      541 ttcgaggcac aggggtctat tctcgtcttc aggcctttct ggaggacaat agctatgctt
      601 atatacggct aaatccttta aaactaagaa gcaactagac agtttgcgag tccgtaaaac
      661 caatcagatt gacgctgaaa agctagcttc gtcacaattc atccttaacc gcaaaccaac
      721 ttatgttcaa gaagaagtct atcaaaattt gcgtgacctc agtcgattct atcagaatct
      781 gacagaagac atcgttagga ctaagaatag cctgcacaag gtgcttcaaa ttgcctttcc
      841 agaaataaag aaccttctct ctactcctac aggggaacaa tattggaacc tcgtgaccat
      901 ctttccaacc aagcattgga ggctgaaatt atcagtagtt gagctaaaag aagccatcgt
      961 aattcaactt ctaaacggat ttctgagaac agagttggac gattggctga aaagttgagc
     1021 gagctggccg aacagtccta tcttgccatt tcaaaaacct ctcccatgac agaagaggtt
     1081 aagtatcatg cacaggaact gttgagactg acaaaccgca aggatcagga cttagcacaa
     1141 atgattgaat tggctgaacc attacctgaa tacgagattc tgctctctat tcctggtatc
     1201 gcagaaacaa cagctacaag cattattggc gaattggaga cattcgtcgc tttcggtctg
     1261 ccaaccaaat caatgccttt atcagtattg acctcagaca ctatgaatct ggcaatttcc
     1321 tagctcaaga acatatcacc aagcgtggaa atccttacgc gagaaaaatt ctctataagt
     1381 gcgtccacaa tattgcttca gctagtcata ccaatccttg tcatatcgcg gacttttatg
     1441 agaaacgaaa aagacaatcg cagacgactt caaccaagcc atatacgatt gtctctatac
     1501 atcgcctcat ccggacaatg tattacctca taacgcataa caaactttac gactacactt
     1561 taacccaaag tcattaaagt catctatgtc ctatcattgt aacaccttat tttttaatac
     1621 cagataagtg tcttttaagt gtgcccaaat ttcaaaaaac agctcgcaat tatcttctaa
     1681 acattccttt gatactcatt cagaaaacct tttgagctag aatatcgtat gtcccttaac
     1741 aaatggtatg tataaaagag ctaaaaaacc actcatgata tgaacgagtg gttatgactg
     1801 aaatattaca tacctttgta tcatttttgc acaatggtca aatttcttgt ttgaaaaact
     1861 acagtaagcc taatcaaagc tctcaatgta tcattaaaac ttccttccaa agaataggaa
     1921 gttctatcaa aattcttaat tagattttac ttcttctaag accctgcgct ctcatatgca
     1981 tccaaacctt tgttccataa ttttaatgat aaggtaaaaa atattaatga gataaggatc
     2041 aatccaccaa tattgaacaa tccatccttg tctttcaaga aatagctagc tgggtaatag
     2101 gctgtaaaag caaaaggaat gataaaacta atcaaccaac gtaaaaacga atggtaaatc
     2161 gcaatcgggt attttgcaaa atcattaaac atgtaaaaaa tataaattat tgccccagat
     2221 tgtttagtcc aaaaagcaat actagctgtt acaattttta aagaggtata aattaaggtt
     2281 gcaaagggaa tactgattaa aaagagaaaa acctttgccc aagtccaagt aagactagtt
     2341 attgtcatta acagcaataa gacgcctact aacaattctc caagagcatc aatttgaaac
     2401 gtttctacta aaatatgaaa caaagggcta atgggtctag tcaaatactt atcaaattct
     2461 cctttacgaa ttaaatgttg tcctaaagcc cacagattat caaaaaagag atggtcaatt
     2521 cccttaggaa tgagagaaaa accataaata aaagcaacct gatgaaaact ccagccatca
     2581 agtaagggaa tatgttgaaa caaaatattt agaaacagca tgtttaaccc ttgtgtcaaa
     2641 aagacaccca caacaccaac taaaaaatca gccttatact ccataatctg tttaagatat
     2701 tgtcggataa aaatcaggtg catgcgttga tatttcttca ttctaacctc cttgaatagt
     2761 tatataattc tgtacgcact tccaaatcag ttgggataag gcaatcataa taaacagcca
     2821 gaataattgt agcgagagcg cctgaatcat ttgactcatg ctatactttt ctataataac
     2881 catcaccggg gtatagatta aagaagaaaa tggcaaaaaa gataatagtt cggcaataat
     2941 ttttggaaaa aatgtcagag gaaccaaact tccagataaa aaggcaacta aagaattttt
     3001 caaaagattt gatccccata agtttttaaa cacaaaagct gaaaaaccaa agcaaatatt
     3061 gaaaaaaaat taatcaaaaa agctaagatt aagctaagaa ggtaaactgt ggttattaaa
     3121 acaatttgta agaaggactc acctgataag agctttagac ctgcaatcag aattacaaat
     3181 ggtagaccaa cactaacaaa aactagccat ctagacccaa tttctgtgaa aagataagac
     3241 attgcaaaat gaactggacg aagcagtcgc ataataatag agccatcctt tacttcccat
     3301 ccaatcataa aagaactatc tgattttgtc agtagattcg tcacaaaact catgatgata
     3361 tataaggtca tatcagataa agtaaaacct tgaatgagag actggtgaga tgaatcaaac
     3421 acagctttcc acaagtaaaa tgctacaaag gcccccatca catccccaat gcgataaaga
     3481 aaaaaattga cacgatacgt gattaattct tggattccag cgctaacaaa aggcttatag
     3541 cgtttccata atttagtcat cctaaagctc ctttcgatag aagcgacgaa taatatcttc
     3601 aatattcgca tccgtcatct ttaaatcacg gatcgtaaaa tcagacaaag tttgttgaat
     3661 aatgtcagcc gtttgatact gcgagctgtc gtactgaata tcaagtgaca attcctgtct
     3721 cgtcacatag atatcagaaa gtccttcaaa atgagagaca atataatcct gcccaggatg
     3781 tagttcaaaa gagagagtct tcatcttccc gaaagtcttt ttcagttgat tcacagttcc
     3841 atcaaagatt tctcggccct tatcaatcat aaaaatacga tcacataact gttcaatatc
     3901 acctaaatcg tgggtcgtta aaagtatggt cgtctcttct tcttgattaa tctgtgtaat
     3961 ggcacgtcga atattatcct tgaccgaaac atctaaacca atagtaggct catctaggaa
     4021 aagaactttc ggattatgca ataaggaggc cgcaatatcc gccctcatac gttgacctag
     4081 agatagagtt ctgacaggat cttgaataaa ttccttcaaa tctaaaactt catttagaaa
     4141 atccatgcgt ttttgaaaga ccgcatcagg aacatcataa atttccttta aaaccgagta
     4201 agtctcctac aaagccaaat cccaccaaag ttgagttcgc tgcccaaaaa ctacaccaat
     4261 atctttaaca tagccttgac ggttctcttg aggaatcttt ccattgatac gacaaaaacc
     4321 tgatgttggt ttcaaaatcc ccgtcaacat cttgatagtt gttgatttcc ccgctccatt
     4381 tgcgccaata aagcctaaaa tttgtccttt gggcacctca aatgataaat ctttaacagc
     4441 ttcaaagact tgtctcttgg gatgaaaaaa agagcgaaaa gctcccttta agccaggttc
     4501 ctttattgtt ttcacaaaat ttttctgaag atgctctact gttatcattt ttataaatca
     4561 ctcctttcgt ttcactcaag ttataatatc aacaaaaatt gtagcatact acagtaaagt
     4621 taagaaaatt taccatcatt acaaaccata tgaaaaaagc tactaaaact atgccatctt
     4681 gtattttatc tgtaagtaag ctaaattact caagtacaaa gaattatgac gaagaacata
     4741 taaatttata attggataaa ctatagattt cagcaaacga agttatccca atataaaaat
     4801 actttaataa ctgaagatat tgacagga
//
LOCUS       DAVLBN010000096         4663 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLBN010000096 DAVLBN010000000
VERSION     DAVLBN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.096"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1341
                     /locus_tag="VXC24_002059"
     rRNA            <1..1341
                     /locus_tag="VXC24_002059"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1393..1465
                     /locus_tag="VXC24_002060"
     tRNA            1393..1465
                     /locus_tag="VXC24_002060"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1426..1428,aa:Ala,seq:tgc)
     gene            1590..4491
                     /locus_tag="VXC24_002061"
     rRNA            1590..4491
                     /locus_tag="VXC24_002061"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4568..>4663
                     /gene="rrf"
                     /locus_tag="VXC24_002062"
     rRNA            4568..>4663
                     /gene="rrf"
                     /locus_tag="VXC24_002062"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1292 a          961 c         1383 g         1027 t
ORIGIN      
        1 aaaaggtgca cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt
       61 aagggctcac caaggcgacg atacatagcc gacctgagag ggtgatcggc cacactggga
      121 ctgagacacg gcccagactc ctacgggagg cagcagtagg gaatcttcgg caatggacgg
      181 aagtctgacc gagcaacgcc gcgtgagtga agaaggtttt cggatcgtaa agctctgttg
      241 taagagaaga acgagtgtga gagtggaaag ttcacactgt gacggtatct taccagaaag
      301 ggacggctaa ctacgtgcca gcagccgcgg taatacgtag gtcccgagcg ttgtccggat
      361 ttattgggcg taaagcgagc gcaggcggtt agataagtct gaagttaaag gctgtggctt
      421 aaccatagta ggctttggaa actgtttaac ttgagtgcaa gaggggagag tggaattcca
      481 tgtgtagcgg tgaaatgcgt agatatatgg aggaacaccg gtggcgaaag cggctctctg
      541 gcttgtaact gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt
      601 agtccacgct gtaaacgatg agtgctaggt gttagaccct ttccggggtt tagtgccgta
      661 gctaacgcat taagcactcc gcctggggag tacgaccgca aggttgaaac tcaaaggaat
      721 tgacgggggc ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc
      781 ttaccaggtc ttgacatccc tctgaccgct ctagagatag agttttcctt cgggacagag
      841 gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc
      901 aacgagcgca acccctattg ttagttgcca tcatttagtt gggcactcta gcgagactgc
      961 cggtaataaa ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg
     1021 gctacacacg tgctacaatg gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat
     1081 ctcttaaagc cagtctcagt tcggattgta ggctgcaact cgcctacatg aagtcggaat
     1141 cgctagtaat cgcggatcag cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg
     1201 cccgtcacac cacgagagtt tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag
     1261 ccgcctaagg tgggatagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg
     1321 tgcggctgga tcacctcctt tctaaggata aggaactgcg cattggtctt gtttagtctt
     1381 gagaggtctt gtggggcctt agctcagctg ggagagcgcc tgctttgcac gcaggaggtc
     1441 agcggttcga tcccgctagg ctccattggt gagagatcac caagtaatgc acattgaaaa
     1501 ttgaatatct atatcaaata gtaacaagaa aataaaccga aaacgctgta gtattaataa
     1561 gagtttatga ctgaaaggtc agaaaataag gttaagttaa taagggcgca cggtggatgc
     1621 cttggcacta ggagccgacg aaggacgtga caaacgacga tatgccttgg gtagctgtaa
     1681 gtaagcgatg atccagggat ttccgaatgg gggaacccaa caggtagtac ctgttaccca
     1741 catctgttaa ggatgtgagg aggaagacgc agtgaactga aacatctaag tagctgcagg
     1801 aagagaaagc aaaagcgatt gccttagtag cggcgagcga aacggcagaa gggcaaaccg
     1861 aagagtttac tcttcggggt tgtaggactg caatgtggac tcaaagatta tagaagaatg
     1921 atttgggaag atcagccaaa gagagtaata gcctcgtatt taaaatagtc tttgtaccta
     1981 gcagtatcct gagtacggcg ggacacgtga aatcccgtcg gaatctggga ggaccatctc
     2041 ccaaccctaa atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa
     2101 agcaccccgg gaggggagtg aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc
     2161 ccgttaatgg gtgagagcgt gccttttgta gaatgaaccg gcgagttacg ttatgatgcg
     2221 aggttaagtt gaagagacgg agccgtaggg aaaccgagtc tgaatagggc gccttagtat
     2281 catgacgtag acccgaaacc atgtgaccta cccatgagca ggttgaaggt gcggtaagac
     2341 gcactggagg accgaaccag ggcacgttga aaagtgcttg gatgacttgt gggtagcgga
     2401 gaaattccaa acgaacttgg agatagctgg ttctctccga aatagcttta gggctagcgt
     2461 cgacattaga gattcttgga ggtagagcac tgtttgggtg aggggtccat cccggattac
     2521 caatctcaga taaactccga atgccaatga attatggtcg gcagtcagac tgcgagtgct
     2581 aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtccca aaataattgt
     2641 taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag aagcagctat
     2701 tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg
     2761 ggctaaaaca atttaccgaa gctgtggata cctttatagg tatggtagga gagcgttcta
     2821 tgtgtgatga aggtataccg tgaggagtgc tggaacgcat agaagtgaga atgccggtat
     2881 gagtagcgaa agacaggtga gaatcctgtc caccgtaaga ctaaggtttc caggggaagg
     2941 ctcgtccgcc ctgggttagt cgggacctaa ggagagaccg aaaggtgtat ccgatggaca
     3001 acaggttgat attcctgtac tagagtatgt agtgatggag ggacgcagta ggctaactaa
     3061 agcagacgat tggaagagtc tgtctaagca gtgaggtgtg aattgagtca aatgcttaat
     3121 tctataacat tgagctgtga tggggagcga agtttagtag cgaagttagt gacgtcacac
     3181 tgccaagaaa agcttctagc gtttaaacat actctacccg taccgcaaac cgacacaggt
     3241 agtcgaggcg agtagcctca ggtgagcgag agaactctcg ttaaggaact cggcaaaatg
     3301 accccgtaac ttcgggagaa ggggtgctga ctttaagtca gccgcagtga ataggcccaa
     3361 gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta tagggggtga
     3421 cgcctgcccg gtgctggaag gttaagagga gtgcttagcg taagcgaagg tatgaattga
     3481 agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat tccttgtcgg
     3541 gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac gagagactcg
     3601 gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa agaccccatg
     3661 gagctttact gcagtttgat attgagtgtc tgtaccacat gtacaggata ggtaggagtc
     3721 taagagatcg ggacgccagt ttcgaaggag acgctgttgg gatactaccc ttgtgttatg
     3781 gccactctaa cccagatagg tgatccctat cggagacagt gtctgacggg cagtttgact
     3841 ggggcggtcg cctcctaaaa ggtaacggag gcgcccaaag gttccctcag aatggttgga
     3901 aatcattcgc agagtgtaaa ggtataaggg agcttgactg cgagagctac aactcgagca
     3961 gggacgaaag tcgggcttag tgatccggtg gttccgtatg gaagggccat cgctcaacgg
     4021 ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat cgacggggag
     4081 gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc caagggttgg
     4141 gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt
     4201 ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg agaggaccag
     4261 agtggactta ccgctggtgt accagttgtc ttgccaaagg catcgctggg tagctatgta
     4321 gggaagggat aaacgctgaa agcatctaag tgtgaaaccc acctcaagat gagatttccc
     4381 atgattatat atcagtaaga gccctgagag atgatcaggt agataggtta gaagtggaag
     4441 tgtggcgaca catgtagcgg actaatacta atagctcgag gacttatcca aagtaactga
     4501 gaatatgaaa gcgaacggtt ttcttgaatt gaatagatat tcaattttga gtaggtatta
     4561 ctcagagtta agtgacgata gcctaggaga tacacctgta cccatgccga acacagaagt
     4621 taagccctag aacgccggaa gtagttgggg gttgccccct gtg
//
LOCUS       DAVLBN010000097         4229 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLBN010000097 DAVLBN010000000
VERSION     DAVLBN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.097"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            17..2065
                     /locus_tag="VXC24_002063"
     CDS             17..2065
                     /locus_tag="VXC24_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494105.1"
                     /translation="MFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWEGSWKPFAEFLSNTFGISIETVADL
                     LGGIILEALKLLADTIKLVTDGFTAFSDWCKENKEIISTIASVIGTLATVWQGIKFLS
                     WAEQAGGLAGAFELLSSKVSFIVSGIKNLGLALKALTFDKLVSFGETIYLNALYAKDF
                     VVNSGKTIAQLGKTALELGKSALAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNA
                     ALAVLTSPITLVIAAIAALIGIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEF
                     FSGLWTKLQEIFEPIGQWFSEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTW
                     LGDKFKSGRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQK
                     IGSWFGDRWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKI
                     KLPHFNISGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWI
                     SILAQKLAERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI
                     "
     gene            2074..2424
                     /locus_tag="VXC24_002064"
     CDS             2074..2424
                     /locus_tag="VXC24_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494106.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPRYTFTEK
                     FKPWSGAKFNLVER"
     gene            2429..>4229
                     /locus_tag="VXC24_002065"
     CDS             2429..>4229
                     /locus_tag="VXC24_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0494107.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKHIKQQDGIEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAETEIAKQVEALSRTKNELAGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAETEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLAN"
BASE COUNT         1254 a          787 c         1039 g         1149 t
ORIGIN      
        1 cagggcgcta gtcgctttgt ttgataatgt tggtaacctt tccgaggcag taggaaacat
       61 agctcaggac ttttctagtg ctttctacga cgtcattacc tcaactggtg cggttcgtat
      121 cggtagcgct attgtgtcaa ctctgttgag tttgacatct accattgttg aagttggtag
      181 taaattagca ggaagtttgt ttaaaggttt tgaaaaagtc gttgtgacaa gcgctcctaa
      241 aatttcatca gtcttccaaa gtttattaga tactgttgcg cctgtatttg agagcattga
      301 aaggtctgtt aacaaatttg gcgatggctt aagtcgtgtt tatgatgaac atgtagtccc
      361 tgctattaac tctattgcta atgcttttaa tgggctaatt gacattattc aaatactttg
      421 ggaaggaagt tggaagcctt ttgcagagtt cttgtctaac acattcggca taagtattga
      481 aaccgtcgct gatttactag gcggtatcat actagaggca ttgaagttac tagctgatac
      541 aatcaagcta gtaaccgatg gttttactgc tttttcagat tggtgtaaag aaaataaaga
      601 gattatctcc acaatcgcta gtgtgattgg tacgcttgca accgtgtggc aaggaattaa
      661 gttcttgtct tgggctgaac aagctggagg acttgcaggg gcattcgaat tattaagtag
      721 taaggtttcc tttattgtta gcggaattaa aaatcttgga ctagctttga aagctttgac
      781 atttgataaa ttggtcagct tcggagaaac catctatttg aatgcgttgt atgcaaaaga
      841 ttttgttgtc aattcaggta aaacaattgc acagctaggg aaaactgctt tagaacttgg
      901 taaatcagct ctagcatgga ctgctcatac agcgaaaatg ggattagcaa ccgcggcgga
      961 atttgcacat tctgttgcag caggagtcgc tacagctgca acatgggctt ttaatgcagc
     1021 gttagcagtt ttgacaagtc caataacctt agttattgca gcaatcgcag ccttaattgg
     1081 tatcggtgtc ttgctctacc aaaattggga cactgttgtt gagtttgcta aaactgcatg
     1141 gcaaggacta tgtgatttta tcagtggtat ttgtcaagcg attggcgaat ttttcagcgg
     1201 tctatggacg aaactccaag aaatctttga gccaataggt caatggttta gcgagaagtt
     1261 ccagcaagca tgggatgcta ttggaaatat atttggcaac ttaggctctt ggtttggtgg
     1321 ccgttggaat gattctaaaa acgcacttgc cgaagcaaat acttggcttg gtgataagtt
     1381 caagtcaggt cgggataaag tgaactcagc ttttgaaaaa gttggctctt ggttcggtga
     1441 ccgttggaat gatatcaaag atggagtgaa agaagctgat acatggtttg gagagaaatt
     1501 tgagagtgca aaaaagaaaa ctcagaatcc tttccaaaaa atcggttctt ggtttggcga
     1561 tagatggaaa gatatgcaag atgccttgaa agaaatcccc aactggttca agaatctgtt
     1621 taatgatgca atggataatg ctaaaaacat cgttaaaagt ggtatcgata aactaaaaag
     1681 cttctttaac tttgattgga gcttaccaaa aatcaaactc cctcacttta atatatctgg
     1741 tagcttcagc ttgatgcctc ctagaattcc atcattctct gtagattggt atgcacgagg
     1801 tggtgtattc aactctccta gcatcattgg ggtcggagaa gctggtcaag aagcggtaat
     1861 gcctcttgaa cggaatacag gatggatttc tatcttggct caaaaactgg ctgaaagaat
     1921 gcctgctaat aatgtaccta caggttattc attaccggct ggcgacatcg ttatccaaat
     1981 cgcaggacat gagttcggtc gggtagcaat ccaagaaatc aacaaggagc atgaacgagc
     2041 aggtcaaacc ttgctcaaga tttaggaggt taaatggcac aattgacaat caatggggtg
     2101 gctgtgaagc ctcccaaatc ttttcaagtc ggtattcaag atatcgatgg agagacaggg
     2161 cgtaatgcca atggcgacat gatgcgtgac cgtatcacga ccaaacgcaa actagactgt
     2221 gaatggggta tgatgactca gggagaatta agtcagcttt tacatgctgt atcatctgaa
     2281 ttttttgagg tgtcttatcc agaccccatg gatggccaag tcacaaagac tttctatgtc
     2341 ggtgatagga cagctcctag atataccttt actgagaagt ttaaaccttg gtctggcgct
     2401 aaatttaatc tggtagagag gtaagaaaat ggacgcttta actagacgac aatttgacag
     2461 agccatgttt gccaaggaaa ggacgctggc tattcgtgtt ggtgattatg cttcacggga
     2521 tatcaaagag gctagttttg agtatggcta cattaagggc gatacttata agcctggtgg
     2581 aacctgcgct ggtagcggta aaattacctt taccagtatc attaccacgt tcaataagct
     2641 ggataccctg caccctgaga ttggtctact ggttggggat acctaccagt gggtcaagat
     2701 gggggaatac ttcatcaacg atattgagat tgaccgaaac cgaaacacta ccacacttga
     2761 acttatggat ggtatgttta agctcaatcg tgagtatgtg acagatttgc atttcccagc
     2821 tgaagtacga gaggttattc aggaaatctg cctgaaaaca ggcattgagt tagcgaatga
     2881 ctatttcgga atcagcgcga tgcgttatca tattgagcaa gttcctgagg gcaagaaact
     2941 ttcctttagg gatatgctga gcgctatgac tcagatgatt gggatgtctt gtttcttcaa
     3001 cagagaaggc aagatggaaa tccgtgattt gactgagtcc aatatcacga tcaacgctga
     3061 cagttacttc ttgcatggct tgaccaagag tgagattgag tatcagatag ctggtatcac
     3121 ttgtaagacg gacaagaagt ctctgacggt cggtatgaag acaggccggt ctttggaact
     3181 ggacaatgtc ttcatgaccc agagcgcttt aaatgacctg tattacaaac tgaaaaacct
     3241 aacttactat ccgtataatc tcaactacca agggcattta ctgcttgagg tcgggcagtg
     3301 ggtaaccatt cagaccaata agaaagagac ctttaaagtt cctgtgttaa gtcagagctt
     3361 tacttttaaa ggtggtctga gagggcgtat cagcgcagat agtaaggctg gaaacgatac
     3421 tcagtattct tacgagggta cgattaccaa gcatattaag caacaagatg gcattgaagc
     3481 gaaaatccaa gcgcagattg aagcagcaga taaagatttt gaccaaaagg ttgacaaaat
     3541 caaaaaagac tttaacgatc aagtagaact ggccaaagcc agagctgaag aagtcaagag
     3601 agaactgtct gacactatca atcagcgatt taatagcttt gacaacgggc cattgaaaga
     3661 aactaagcgc aaggctgagg aagctttgcg aaatgctggc gcaagtaccc tgcttgcaca
     3721 ggaagctaag cggattgggc tggattctgt cgctagactt gaagcgttta agtcgcagac
     3781 tacgagcgca caaacggctc tgtcgggtga cttggacgct ctgaaacgga ctatcgcgaa
     3841 tgatattcga ccgaagcaag cacaggctga aactgagatt gccaagcaag ttgaagcact
     3901 tagccggact aaaaatgaac tggctggcgc aagtacccta cttgcacagg aagctaagcg
     3961 gattgagctg gattctgttg ctagacttga agcgtttaag tcgcagacta cgagcgcaca
     4021 aacggctctg tcgggtgact tggatgccct gaaacggact atcgcgaatg atattcgacc
     4081 gaagcaagca caggctgaaa ctgagattgc caagcaagtt gaagcactta gccggactaa
     4141 aaatgaactg gctggcgtga agtcagcgca agcgacgtat gaggagacga cgactcgtag
     4201 actgtcagaa ctgaccaact tggccaatg
//
LOCUS       DAVLBN010000098         4225 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLBN010000098 DAVLBN010000000
VERSION     DAVLBN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.098"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            713..1705
                     /locus_tag="VXC24_002066"
     CDS             713..1705
                     /locus_tag="VXC24_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0494108.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VXC24_002067"
     CDS             1707..2525
                     /locus_tag="VXC24_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0494109.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDIMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VXC24_002068"
     CDS             2527..3312
                     /locus_tag="VXC24_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0494110.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="VXC24_002069"
     CDS             3351..3629
                     /locus_tag="VXC24_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0494111.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3614..3811
                     /locus_tag="VXC24_002070"
     CDS             3614..3811
                     /locus_tag="VXC24_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0494112.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4087..>4225)
                     /locus_tag="VXC24_002071"
     CDS             complement(4087..>4225)
                     /locus_tag="VXC24_002071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494113.1"
                     /translation="SKHCFEVVDRTDEVSNHTHGKATLTWFEEIFEEYKSKTFVNRDT
                     L"
BASE COUNT         1180 a          728 c          906 g         1411 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaactctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatatcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtca
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattttt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagtta atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtaga ttttgtggtt ggtgtcttgg gagtctttct gactcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa gaaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactag atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcctcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cacaacctca aaacagtgtt ttgag
//
LOCUS       DAVLBN010000099         4013 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLBN010000099 DAVLBN010000000
VERSION     DAVLBN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.099"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(148..1209)
                     /gene="dinB"
                     /locus_tag="VXC24_002072"
     CDS             complement(148..1209)
                     /gene="dinB"
                     /locus_tag="VXC24_002072"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0494114.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1558..3882
                     /gene="pflB"
                     /locus_tag="VXC24_002073"
     CDS             1558..3882
                     /gene="pflB"
                     /locus_tag="VXC24_002073"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0494115.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         1208 a          846 c          778 g         1181 t
ORIGIN      
        1 agaaaaacct tgaaggggca actcttcaag gttttatact cttagaaaat ctcttcaaac
       61 cgcgtcagct ttatctgcaa cctcaaaaca gtgttttgag cagcctgcgg ctagcttcct
      121 agtttgctct ttgattttca ttgagcttta aaatccagtc agggtaatcc ccaataggcg
      181 gacacctctt tctttctcgc ttaattcttc atagagttgc agggctattt ggcttatctg
      241 actagcatct tgtgtttttt gagcaagact ttttcgtttg gtaagagttg aaaagtcctc
      301 gtagcggatt ttcaaaatga caatttttcc agctttttct tgttgatgta gattgagagc
      361 gactttttct gatagaagag tcagctcttt tttgatatct tcctcagcaa ggagaatctt
      421 cccgtaggtt ttctccttgc cgattgattt acggatgcga ttggatttga ctggagagtt
      481 gtgaatgcca cgagcctttc gatacagatc atagcctagt ctaccaaaac ggtctattag
      541 ggttacctca ggaacttcaa gtaaatcagc accagtaaaa acgcccattt gatgaagacg
      601 ttctactgtc ttttttccta ctccatgaaa tttggaaata tccatttgtt tgagaaaatc
      661 ctcagcctgt tcaggtagaa tcactgtcaa accatgtggt ttttgataat cactcgccat
      721 tttagctaag aatttgttgt aagaaacgcc tgcggaagca gttagatgga gttcttgcca
      781 gatatctttt tgaatgaggc gagcaatttt gaccgctgac ttgataccga gtttattttc
      841 tgtcacatcc aaataggctt cgtcaatgct catgggttca atcaaatctg tatagcgctt
      901 aaaaatagct cgaatctgga gtcccacaga cttgtatttc tcataattcc ctgagataaa
      961 gacagcctgg ggacaacgtt cataagcttc cttggaactc atggcagaat ggacaccaaa
     1021 agctcttgcc tcataactac aggtagaaac gactccccgt ccacctgttt gccgagggtc
     1081 gcttccaata atgacaggtt ttcctctgag tttaggatta tccctgattt ccactgcagc
     1141 aaaaaaggca tccatgtcaa tatggatgat ttttcttgac aaatcattta acaaaggaaa
     1201 aatcaacatg cctagcacct ttttatactc ttcgaaaatc tcttcaaacc acgtcagctc
     1261 tatctgcaac ctcaaaacag tgttttgagc aatctgcggc tagcttccta gtttgctttt
     1321 cgatttccat tgagtgttac tgcttatttt cttttattat accctttttt ctgaaaaaaa
     1381 gaaaaaagga ctttattttt tcaaaaatat aatacagttt gaaataaaat atagactgtt
     1441 ttagaaaaga aagtgtaaaa atagggaatt ttcacttgtt gaaatcggtt actatatggt
     1501 atacttgtct tatgaatgta acagatgact gttactagaa aaaaagagga cattaatatg
     1561 gttgttaaga cagttgttga agcacaagat atttttgaca aagcttggga aggcttcaaa
     1621 ggcgtagatt ggaaagaaaa agcaagtgta tcacgatttg tacaagctaa ctacacacct
     1681 tatgatggag acgaaagctt ccttgcagga ccaacagagc gttcacttca catcaagaaa
     1741 attgtagaag aaactaaagc acactacgaa gaaactcgtt tcccaatgga cactcgtcca
     1801 acatctatcg ctgatatccc tgctggattt atcgacaaag aaaatgaagt tatctttggt
     1861 atccaaaatg atgaactctt caaattgaac ttcatgccaa aaggtggtat ccgtatggct
     1921 gaaactactt taaaagaaaa tggatacgaa ccagacccag ctgttcacga aatcttcact
     1981 aaatatgtaa caacagttaa cgacggtatt ttccgtgcct acacttcaaa tattcgtcgc
     2041 gctcgtcatg cacacactgt aactggtctt ccagatgcat actcacgcgg acgtatcatc
     2101 ggtgtttacg cacgtcttgc tctttacggt gcagactact tgatgcaaga aaaagtaaac
     2161 gactggaatg caatcaaaga aatcgatgaa gaaacaatcc gtcttcgtga agaagtaaac
     2221 cttcaatacc aagcattgca acaagttgtt cgcctgggtg acctttacgg ggttgatgtt
     2281 cgcaaaccag cgatgaacgt gaaagaagca atccaatggg ttaacattgc tttcatggct
     2341 gtctgccgtg tgattaacgg tgctgctaca tctctaggtc gtgtaccaat cgtattggac
     2401 atctttgcag aacgtgacct tgctcgtggt acatttactg aatcagaaat ccaagaattc
     2461 gttgatgatt tcgttatgaa acttcgtaca gttaaatttg ctcgtacaaa agcttatgac
     2521 caattgtact caggtgaccc aacctttatc acaacttcta tggctggtat gggtaacgac
     2581 ggtcgtcacc gtgttactaa gatggactac cgtttcttga acacacttga caacatcggt
     2641 aactcaccag aaccaaactt gacagttctt tggactgaca aattgccata caacttccgt
     2701 cgctactgta tgcacatgag ccacaaacac tcttctatcc aatacgaagg tgtaacaaca
     2761 atggctaaag acggatatgg tgaaatgagc tgtatctcat gctgtgtgtc tccacttgat
     2821 ccagaaaatg aagaacaacg ccacaacatc cagtacttcg gtgctcgtgt aaacgttctt
     2881 aaagcccttc ttactggttt gaatggtggt tacgacgatg ttcacaaaga ctacaaagta
     2941 tttgatatcg aaccaatccg tgacgaagtt cttgaattcg aatcagttaa agcgaacttt
     3001 gaaaaatctc ttgactggtt gactgacact tacgtagatg ccttgaacat catccactac
     3061 atgactgata gatacaacta cgaagctgtt caaatggcct tcttgccaac taaacaacgt
     3121 gccaacatgg gattcggtat ctgtggattt gctaacactg ttgatacatt gtcagctatc
     3181 aaatacgcta cagttaaacc aatccgtgac gaagatggct acatctacga ttacgaaaca
     3241 atcggtgact acccacgctg gggtgaagat gacccacgtt caaacgaatt ggcagaatgg
     3301 ttgatcgaag cttacacaac tcgtctacgt agccacaaac tatacaaaga cgcagaagct
     3361 acagtatcac ttttgacaat cacatctaac gttgcttact ctaaacaaac tggtaactca
     3421 ccagttcaca aaggtgtata cctcaacgaa gatggttctg tgaacttgtc taaacttgaa
     3481 ttcttctcac caggtgctaa cccatctaac aaagctaaag gtggttggtt gcaaaacttg
     3541 aactcacttt ctagccttga ctttagttat gcagctgacg gtatctcatt gactacacaa
     3601 gtatcacctc gcgctcttgg taagactcgt gatgaacaag ttgataactt ggtaacaatc
     3661 cttgatggtt acttcgaaaa cggtggacaa cacgttaact tgaacgttat ggacttgaac
     3721 gatgtttacg aaaaaatcat gtcaggcgaa gacgttatcg tacgtatctc tggatactgt
     3781 gtaaacacta aatacctcac tccagaacaa aaaactgaat tgacacaacg tgtcttccac
     3841 gaagttcttt caatggatga cgccttggat gcattgagct aatcaagttc ggctctttgt
     3901 caactgcagt gggttgaagt cggctaagct cgagaaagga caaaattcgt cctttctttt
     3961 ttgatgttca gagcgataaa aatccttttt ttgaagtttt caaagttccg aaa
//
LOCUS       DAVLBN010000100         3920 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLBN010000100 DAVLBN010000000
VERSION     DAVLBN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.100"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1453)
                     /locus_tag="VXC24_002074"
     CDS             complement(<1..1453)
                     /locus_tag="VXC24_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0494116.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEI"
     gene            complement(1458..1808)
                     /locus_tag="VXC24_002075"
     CDS             complement(1458..1808)
                     /locus_tag="VXC24_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494117.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            complement(1817..3904)
                     /locus_tag="VXC24_002076"
     CDS             complement(1817..3904)
                     /locus_tag="VXC24_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494118.1"
                     /translation="MFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
BASE COUNT         1114 a          977 c          718 g         1111 t
ORIGIN      
        1 caatctcagc ttcagcctgt gcttgcttcg gtcgaatatc gtttgcgata gttcgtttta
       61 gaacatccaa gtcacccgac agagccgttt gtgcgctcgt agtctgcgac ttaaacgctt
      121 caagtctagc aacagaatcc agcccaatcc gcttggattc ctgagcaaga gaactacttg
      181 cgccagcatt tcgcaaagct tcctcagcct tgcgcttagc ttctttcaat ggcccgttgt
      241 caaagctatt aaagcgctga ttgatagtgt cagacagttc tctcttgact tcttcagctc
      301 tggctttggc cagttctact tgatcgttaa agtctttttt gattttgtcg accttttggt
      361 caaaatcttt atctgctgct tcaatctgcg cttggatttt cgcttcaaag ccatcttgtt
      421 gcttaatctg cttggtaatc gtaccctcgt aagaatactg ggtatcgttt ccagccttac
      481 tatctgcact gatacgacct ctcagaccac ctttaaagat aaagctctga cttaagacag
      541 gaactttaaa agtctctttc ttgttggtct gaatggttac ccactgccca acctcaagta
      601 acaaatgtcc ttggtagttg agattatacg gatagtaagt taggtttttc agtttgtaat
      661 acaagtcatt taaagcgctc tgggttatga agacattatc aagttccaaa gaccgacctg
      721 ttgtcatacc gaccgtcaga gacttcttat ccgtcttaca agtgatacca gctatctgat
      781 actcgatttc actcttggtc aatccatgca agaagtaact gtcagcgtta atcgtgatgt
      841 tggactcggt caaatcacgg atttccatct ttccttctcg gttgaagaag caagacatcc
      901 caatcatctg agtcatagcg ctcagcatat ccctgaacga aagtttctta ccttcaggaa
      961 cttgctcgat atggtaacgc atagcgctga ttccgaaata gtcattcgct aactcaatgc
     1021 ctgttttcag gcagatttcc tgaataacct ctcgtacttc agctgggaaa tgcaaatccg
     1081 tcacgtactc acgattgagc ttaaacatac cgtccataag ttcaagtgtg gttgtgttgc
     1141 ggtttcggtc aatctcaata tcgttgatga agtattcccc catcttgacc cactggtagg
     1201 tatccccaac cagtagacca atctcagggt gcagggtatc cagcttattg aacgtggtaa
     1261 tgatactggt aaaggtaatt ttaccgctac cagcgcaggt tccaccaggc ttataagtat
     1321 cgcccttgat gtagccatac tcaaaactag cctctttgat atcccgtgaa gcatattcac
     1381 caacacgaat agccagcgtc ctttccttgg caaacatggc tctgtcaaat tgtcgtctag
     1441 ttaaagcgtc cattttctta cctctctacc agattaaatt tagcgccaga ccaaggttta
     1501 agcttctcag taaaggtata gctaggagct gtcctatcac cgacatagaa agtctttgtg
     1561 acttggccat ccatggggtc tggataagat acctcaaaaa atttagatga tacagcatgt
     1621 aaaagctgac ttatttctcc ctgagtcatc ataccccatt cacagtctag tttgcgtttg
     1681 gtcgtgatac ggtcacgcac catgtcgcca ttggcattac gccctgtctc tccatcgata
     1741 tcttgaatac cgacttgaaa agatttggga ggcttcacag ccaccccatt gattgtcaat
     1801 tgtgccattt aacctcctaa atcttgagca aggtttgacc tgctcgttca tgttccttgt
     1861 tgatttcttg gatagctacc cgtccgaact catggcctgc gatttgaata acgatgtcgc
     1921 cgtcgctaga aaaaccacct tgtggactaa taccagccat ggcatttact accgcactgc
     1981 tgactactcg tccaagtgtt tggataaatc ctgtattttc aagtggtacg accgcctctt
     2041 taccagcttc accaatcatg gcgattgttg gactatcgac gataccacca cgggcaagac
     2101 gagggaggct aactgtgctt acactaccaa cccatcctag accaggtaag tttctgacaa
     2161 cgcctaaaac tccattaatc attccgatga agtcattgac tacattttca atcgttccaa
     2221 gaaccgcatt gaccgcactc ttaaacgctc cacctacagc gctaccaacc ttttgtccag
     2281 cattgacaaa tatgctttga accgttgacc atacaccgct gaagaagcca ccaattgaac
     2341 taaacgcgtt cttgactgca ttataagcac tagtaaacat attcccaaac caagaagata
     2401 cattcgcaag aacacttgta acatctgccc atctctcgcc aaaccataaa cctagtttgc
     2461 taaagatgtt tgttagacca gtccatgctt tttggaatat gtcagtaaac catgccccga
     2521 tattagccaa agcactagtc acatctgccc aacgttgtcc aaaccatgag ccgattggag
     2581 tgaagatatt aacgatagcg tcccatgcac cttggaatac accagagaac cactctccga
     2641 taccagagaa gatgttgaca atggcatccc atgcttgctg gaacttctcg ccaaaccatt
     2701 gacctatcgg ctcaaagatt tcttgtagtt ttgtccatag accactgaaa aattcgccaa
     2761 tagctcgaca aataccacta ataaaatcac atagtccttg ccatgcagtt ttagcaaact
     2821 caacaacagt gtcccagttt tggtagagca agacaccgat agcaatcaaa gctgcgattg
     2881 ctgcaataat ccatgttatt ggacttgtca aaactgctaa cgctgcatta aaagcccatg
     2941 ttgcagctgt agcgactcct gctgcaacag aatgtgcaaa ttccgccgcg gttgctaatc
     3001 ccattttcgc tgcatgagca gtccatgcta gagctgattt accaagttct aaagcagttt
     3061 ttcctagctg tgcaattgtt ttacctgaat tgaccacaaa atcttttgca tataaggtgt
     3121 tcaaatagat tgtttcacca aaactgacca acttatcaaa tgtcaatgct ttaatagcaa
     3181 gacctagatt cttaatccct ccaacaatca aagagacctt actacctaac aagctgaatg
     3241 ctcctgcaag tcccccggct tgttcagccc atgataagaa attaatcgtt tgccaagttg
     3301 ttatcaaagc caagataggt tctttgtttt ctttacacca gtcagaaaaa acggtgaaac
     3361 catctgccac taacttaata gcatccgcca atagtcccaa agtggctaaa aggccacctc
     3421 ctaataaatc tgaaattcct tcaatactaa caccgaatac tcctgataaa aactcagcaa
     3481 aaggttgcca agaattctcc cagaggattt gtatgatatc aatcagtccg ttaaaagcat
     3541 tagcaataga gttaatagca ggggctacat gttcatcata aacacgactt aagccatcgc
     3601 caaatttgtt aacagacctt tcaatgctct caaatacagg cgcaacagta tctaataaac
     3661 tttggaagac tgatgaaatt ttaggagcgc ttgtcacaac gactttttca aaacctttaa
     3721 acaaacttcc tgctaattta ctaccaactt caacaatggt agatgtcaaa ctcaacagag
     3781 ttgacacaat agcgctaccg atacgaaccg caccagttga ggtaatgacg tcgtagaaag
     3841 tactagaaaa gtcctgagcg atgtttccta ctgcctcgga aatgttacca atattatcaa
     3901 acaaagcgac tagcgccctg
//
LOCUS       DAVLBN010000101         3624 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLBN010000101 DAVLBN010000000
VERSION     DAVLBN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.101"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..240
                     /locus_tag="VXC24_002077"
     CDS             <1..240
                     /locus_tag="VXC24_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0494119.1"
                     /translation="KQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLI
                     KRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(370..1185)
                     /locus_tag="VXC24_002078"
     CDS             complement(370..1185)
                     /locus_tag="VXC24_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0494120.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(1182..2087)
                     /locus_tag="VXC24_002079"
     CDS             complement(1182..2087)
                     /locus_tag="VXC24_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0494121.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            2477..2788
                     /locus_tag="VXC24_002080"
     CDS             2477..2788
                     /locus_tag="VXC24_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0494122.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPLGG
                     G"
     gene            2793..>3624
                     /locus_tag="VXC24_002081"
     CDS             2793..>3624
                     /locus_tag="VXC24_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV0494123.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     M"
BASE COUNT         1237 a          592 c          696 g         1099 t
ORIGIN      
        1 aagcaggttc atcctctttt tcagactgtc tttaaaacct ttctaaagga caaagagaaa
       61 atcgtcaacg cccttcaact acactattct aacgccaaat tggaagcgac caataatctc
      121 atcaaactta tcaagcgcaa tgcctttggt tttcggaact ttgaaaactt caaaaaacgg
      181 atttttatcg ccctgaatat caaaaaagaa agaacgaaat ttgtcctttc tcgagcttag
      241 ctttttttca acccactaca gttgacaaag agccaatcta caagtcacta attttcatat
      301 aacaaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt cgtttttatc
      361 ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga ctttggtaaa
      421 gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt gattgaccag
      481 ttttcctttg gctgtaatcc aggtgttgtt ttcatactgc cgggtattgc ccttggtcag
      541 caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga acagaaattg
      601 actattggca tgactggggt cgttatagac aaagcctgta aactggattg tcttgccctc
      661 aaattcatct ggatagtcgt agatagcctc catgacttcc atatagtttt cattagtgat
      721 ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct tttcataggc
      781 tgattttgaa aaataagaac tagtatctgg tttcaaatat tggcttgtcg tcccttcact
      841 tgtctgaata gctagatccg ttccttccga tagggggaaa tgataacctt tagcagaaac
      901 ggtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg gaatagccag
      961 aagagaaata ctcgtcatct tggccaatcg gctgttcaga tgactgtggg ttttgacttg
     1021 cttcatccag atatacaatt gaacaattgc caagataaag gaaagcacca tggagatata
     1081 ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca gatggaggta
     1141 aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat gactccaatc
     1201 aagagagaat aggctaaaac gaccagagtc acaatcgtaa tgaagtgact aataaatcgt
     1261 gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg gccaatgacg
     1321 agaaaggcca gaactggtgc caaaccgaaa ctcgagagta gagaagcacc tataaaggca
     1381 tccgcctcac tacagagcga aagaagaaag gctaaaagca tcaagagcag gatagcaaaa
     1441 agaggagtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg tattatagaa
     1501 gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc aatggcctgc
     1561 acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg ctcatgacaa
     1621 gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa aattcctagt
     1681 attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa ggagttgcca
     1741 aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt cacaagaaaa
     1801 ggaacggccg tgtaacttgg aacctttttt tccagaaaac gattgatgat ggggacgatt
     1861 ccacattcac aagaagggaa aagtataccg acaaaggtcc caaaaaagat tctcccccaa
     1921 cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc aatcagccct
     1981 gagacaatgc ttcctatcag aacgaaggga agggcttcaa tgataatgga gagaaaaatg
     2041 gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta gtttttcttt
     2101 tctgctttga cttttttctc tttgtcatca gggaaagtaa cttgtttcaa atcagggagt
     2161 ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt gacagccata
     2221 ggtgtacctc gattctaaat tctacctcta ttatactatt attttgcgga aaagggaaaa
     2281 gttaaaattt caaattgagt agctaagaga taatatagct tgatattacc tgatatatat
     2341 cataattgtg ctataattaa ataaaaagaa aatcattatc agaaaattat gggaggtagt
     2401 caaactgact tactcaatta gtgttgtttt gttacatcaa ggagataaaa atagtttatt
     2461 agagtctttg tcaatagtgg agagacaaac attaaaagat atagaagtta ttattgtaaa
     2521 tcaatctaca gaggagatag cttccattag ccaacagatg aatctatcat ttaatattaa
     2581 gattatagat gagaattctt ttgctgagtt gtctgatatg attacaggag attatattac
     2641 gtttctatct tcaaatgatt cattatttga ttggacattt gaaaagatgt atcatgcgat
     2701 aaaattatcc gattctgatg ttgttcttgg tcattttgct gatttggttg atggagtatt
     2761 ttacttttat cctttggggg ggggataatt ggttgacaga aaatttaacg aatgttcaag
     2821 ttttacaaaa gatggatgat acagatcatc gaattagaaa acaatatcgc tcattatttg
     2881 gaaaattatt caatagtaag cttttacgaa aaataaatca atttgatata aacaacctta
     2941 tttggagact ttatattcac tctaaaactg caacctatat taatttcccg acatatatct
     3001 ataaacctgt tatagatgct aaacctctaa aagactccta caaaatcata ttagaaaatt
     3061 atgaaaatag aatcaaagat tgcgccgtct tagaaaacta tgatatagaa agagcgaaaa
     3121 aacaatatat tcaagaattg gcaaatttta gtgcttggtt aaaaaatgac ggtgaatatt
     3181 tagattctga tattgtttat cataagttaa tagctgcaga gaaaggaatt ttcccttttc
     3241 ttgagcttga tagattagat tttacgatta taagtaataa ttgtgttgga ggattaattt
     3301 ataaacagct tggttttcaa tatagaacac cttttgttgg tttatttatt cttcctgatg
     3361 attattataa acttacaaag cattttcgtt attatatgga acaagaactt gttttcgaag
     3421 aggaacttat ttcaccgagc tggactcatg aagtttatcc tttggggcac ttaggagata
     3481 tagatattca ttttctacat tattctagta ttgaagaagc acgaactaag tgggaaaaaa
     3541 gaaaaaaacg cataaattgg aataatcttt attttaaatt tgataataaa gattcagcta
     3601 gtgaagaaat tttaaataag atgg
//
LOCUS       DAVLBN010000102         3581 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLBN010000102 DAVLBN010000000
VERSION     DAVLBN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.102"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            38..1447
                     /locus_tag="VXC24_002082"
     CDS             38..1447
                     /locus_tag="VXC24_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0494124.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            1465..2760
                     /locus_tag="VXC24_002083"
     CDS             1465..2760
                     /locus_tag="VXC24_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0494125.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            2765..3073
                     /locus_tag="VXC24_002084"
     CDS             2765..3073
                     /locus_tag="VXC24_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0494126.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            3070..3378
                     /locus_tag="VXC24_002085"
     CDS             3070..3378
                     /locus_tag="VXC24_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0494127.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1201 a          607 c          702 g         1071 t
ORIGIN      
        1 atactttatg tatagaataa tagaaaggag gttgagcatg aaaaaaaagt tagtatttcc
       61 taatctattt tggtggggag ctgcttctag cggacctcag acagaaggtc aatatggaaa
      121 agtacatgaa aatgtgatgg actactggtt caaaacgcat ccagaagatt ttttcgataa
      181 tgtcggacct cttgtagcca gtaacttttt tcatacttac accgaagatt tccacttgat
      241 gaaggaaatt ggagttaatt ctttccgcac ttccatccaa tggagtcgac tcatcaagaa
      301 tttagagaca ggtgagcctg atccaaaagg tattgctttc tacaatgcca tcattgaaga
      361 agctaaaaag aaccagatgg atcttgtgat gaatttacat cattttgatt taccagtgga
      421 acttcttcaa aaatacggtg gttgggaaag caaacatgta gtggagttat tcgtgaagtt
      481 tgccaagact gctttcacat gctttggaga taaggttcat tactggacaa ctttcaatga
      541 gccaatggtc attccagaag caggatactt atatgctttc cattatccaa atctaaaagg
      601 aaagggaaaa gaggccgtac aagtcatcta taatctaaac cttgctagtg caaaagtgat
      661 tcaactatat cgctcattag aacttgatgg aaagattggg attattttaa acttgacacc
      721 tgcttatcca agaagtaatt ctccagaaga cttagaagca agtcgattta cagatgactt
      781 ctttaacaaa gtcttcttga atccagctgt taaaggaact ttcccagaaa gattggtaaa
      841 acagctagag agagatggcg tgttatggag tcataccgaa aaagagcttc aactgatgaa
      901 atcaaatacg gttgattttc ttggagtaaa ctactaccat ccaaaacgtg ttcaagcaca
      961 agcaaatcct gaagaatatc agacgccctg gatgccagac caatacttca aagagtatga
     1021 atggctggag cgtcgcatga atccatatcg tggttgggaa atttttccga aagccattta
     1081 tgatattgct atgattgtga aggaagaata tggtaatatc ccatggttta tcagtgaaaa
     1141 cggaatgggt gttgaaaacg aagcacggtt tatcgatgaa aatggagtta tcgatgacgt
     1201 gtatcgtatt gaattttatg aagaacattt aagatggcta cataaagcca ttgaagaggg
     1261 aagtcactgt tttggatacc acgcttggac cgcatttgat tgctggtctt ggaataatgc
     1321 atataagaat cgttacggat ttatctccgt tgatttagaa acgcaaaaga gaaccatcaa
     1381 gagctcagga agatggtatc gcaaagtaag tgacaataac ggttttgaag tagaaattga
     1441 ggagtaaaga gaggagatat tcatatgaaa aactcaaaat ttatagacca atttgccacc
     1501 tttgctggta aactagggaa ccaaattcat ttaaaaaccc taagagatgc attcgtaaca
     1561 gtaatgccat tatatatttt ggcaggttta atcgttcttt tgaacaacac ggtatttaag
     1621 tggattttcc aaggggatac attaacaaga ttccaatatt ggggaataac aattgcaaac
     1681 ggtactttaa gtatttcagg tatgattatt gctgtaatgg ttggttattt cttagctaaa
     1741 aacagagatt tcgaaaaccc gttagcagca tcaatgctat cattagtttc tttaattgtg
     1801 atgatgccaa atacagtttc tgtagttcct gacggagcaa aagatgcggt aaacatttca
     1861 ggtgttcttt cattcaacaa cacaggtaca ggcgcaatgt tcgccggggt tatcgtagcg
     1921 attattgcaa cagaattatt cattgaatta tcaaacgtta aagctttaca aatgaacctt
     1981 ggtgaaaata ttccaccagc tgttagtaga tcatttagcg tattacttcc agtcatgacc
     2041 gtcatctcct tatttggggt tgtttcagca ttattattca atataactgg aatgaactta
     2101 atctcaatca ttacaatctt tattcaagaa ccaattcgtc atattggtac aagcttaatc
     2161 ggggtcatta ttatttactc tttaggaaat atgttatggc tatttggtat tcaccaagca
     2221 gttatttaca gtgccatcct agaaccatta ctattaatta acattactga aaacatcact
     2281 gcagcaaata atggacaagc cattccacac atcatcaacc tatcacaaat acaaacattc
     2341 gctttaatgg gtggtagtgg atctacatta tgtttattaa tagcaacatt cttagtgagt
     2401 cgcaatgctg tctctaaaaa cgtggctaaa ttatcttttg gacctggtat cttcaatatc
     2461 aatgaaccag tattattcgg ttacccaatc gtttataaca tttcattagc tattccattt
     2521 atcacagttc cagtccttgg tattttaatc agctacttag caacagttac aggattcatg
     2581 agtcctgcat ttatacaagt tccttggact acaccagtat tcttaaatgc atggttagca
     2641 acagcagggg acgtgagagc agttctagtt caattcatca tctttgcact tggagttctt
     2701 ctatacattc catttatcaa agttaatgac aaagttgttg aacaagaaat ggaaggttaa
     2761 gattatgaaa caaattttat tagtatgtaa tgcgggaatg tcgacaagta tgcttgttaa
     2821 aaaaatgcaa caaagtgcga ctgaacgtgg gattgaaatt tctatccaag caaaatcaat
     2881 gacagaggcg aaaaagaata tccatgaagc agatgtcatt ctaattgggc cacaaattcg
     2941 ttatgagtta cttgctgtga aagaaattgc aggaaatatc cctgtagata ccattgatat
     3001 gcgggattac ggaatgatga atggagcaaa agttctggaa caagcacttg catggatagg
     3061 agaaataaga tgacagaaga aatggaatat atctgttttc agctcattgc caatagtgga
     3121 gcagccaaat catcctttat tgaagccatc caactagcta aggcaggaaa tttaaaagaa
     3181 gcgaaaatta aagttgaaga agcggaagac tccttagtag aagtgcacaa gattcactct
     3241 aatctcatac aaaaagaagc tactggagaa aaaataggat tctccttgct atttatgcat
     3301 gcagaagacc aaatggcttc aacggagatt attcagttgc tatctaaaga attcatcgat
     3361 ctctatcaaa ataaatagga acactgtcgt tcccatctgt ctttattaat gacggctaca
     3421 ttgtaggaac ctccaaaagt tggacaaaat gattgaaagg attggatcct gcattacaca
     3481 agatccaatc cttttctttt actctagttt ttataatatg ttgaatctag aatagtccac
     3541 tgtagtttct aaaaaattgc tggaaatgga tgttaagctc c
//
LOCUS       DAVLBN010000103         3528 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLBN010000103 DAVLBN010000000
VERSION     DAVLBN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.103"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(224..835)
                     /gene="rpsD"
                     /locus_tag="VXC24_002086"
     CDS             complement(224..835)
                     /gene="rpsD"
                     /locus_tag="VXC24_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0494128.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1030..2082)
                     /locus_tag="VXC24_002087"
     CDS             complement(1030..2082)
                     /locus_tag="VXC24_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0494129.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2079..2777)
                     /locus_tag="VXC24_002088"
     CDS             complement(2079..2777)
                     /locus_tag="VXC24_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0494130.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(2944..>3528)
                     /locus_tag="VXC24_002089"
     CDS             complement(2944..>3528)
                     /locus_tag="VXC24_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0494131.1"
                     /translation="PWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQAL
                     IDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSN
                     SGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPN
                     TGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          973 a          787 c          683 g         1085 t
ORIGIN      
        1 agagagaact tttttacgaa aatctattga atatgccata aaagattata ccacattgtg
       61 tactattttt ggttcatttt actatatcac tttggactat atcggtctag ttatgtctca
      121 acgattatag ctggatacta agagaaatca aaaaagcact aagggagaac gtcccaaagt
      181 gcttaatatc aaggcctcaa agcctgtctt attcaataaa atattacaac atcttgttgt
      241 agaattcaac gacaagtgct tcgttgattt ctgggttgat ttcgtcgcgt tctggcaagc
      301 gagtcaatga accttccaac ttttcagcgt cgaatgatac gaatgctgga cgtccaagag
      361 tagcttctac tgcttcaagg attgctggaa ctttcaatga tttttcacga actgagatca
      421 cttgacctgg agttacgcgg tatgatggga tatcaacgcg tttcccgtca acaaggatgt
      481 gaccgtggtt tacgaattga cgagcttgac gacgagtagt cgcgagacca agacggtaaa
      541 caacattatc caaacgacgt tccaaaagaa gcataaagtt gaaacctagg attccacctt
      601 tgatttttgt agcttgtacg aacaagttac ggaattgttt ttcacctaca ccgtaagtga
      661 aacgaagttt ttgtttttca gccaattgca aaccatattc tgacaattta gaacggttgt
      721 ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa ttctttacct gtacctgtaa
      781 gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc tgtataacgt gacatatgaa
      841 tgtcctcctg atataaataa tatttcggtg gaaatagtca cttagaaagc cctgattcgt
      901 gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat aagacacctg ttgacgagct
      961 tcatgctttc ctgctgatat ttcacacaaa atccatttta ccatgaatag ctggatttgt
     1021 aaaggggttt taggctttat tttcactacc agagaggttg agaacgaggg taaaggtact
     1081 tcctagaccg tactggctgc tgactgtgat ttccccaccc aattgatggg ccaattcacg
     1141 cgcaatcgca agtcctaatc catgaccacc tgtcttcatg ttacgcgaag tttcgacacg
     1201 ataaaggcgt ttgaaaatat tttccaaatc ctctggggca atgccctgcc cttcatcggt
     1261 cacactgatt gaaagctggt ccttctccag cttagccacc acttccagct tggttcctgg
     1321 agcagaatat ttaaaagcgt tatcgaccag attcaccaag atacgagaaa gcttagcata
     1381 atctccctca atccgggcag actctgggat tacctgcaag tggacatctc ttctctcctg
     1441 ctcaatcaaa aactgaaatt cactcatgca ctcaattaag agcttgtcca gaaaaatact
     1501 gtctttactg gtagtttcca cctgatttct agctgtgttt agggtcaaaa aattcaactc
     1561 ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg gttgctagat aatgagcttg
     1621 ctccgactcc ttgataatcc catccaaaat cccttctacc gtcgcttgga tcgaagtgat
     1681 aggggtctta atatcatgcg acaactgggc aatcatcaag cccttttctc gttcgctttc
     1741 ttccaaggaa tcaaagctta cctgcaaatc atgggacatc tcattaaaag tttgccctaa
     1801 ttgctgaaat tctacaggac cttgaacctc caaatttgaa ggaaaatcct tggccgctac
     1861 ccgcttggca tgctccttga gtttgcccaa cgacgtaaag actggcaata ggagaaagag
     1921 actaatccca gcaccgacaa ggctggcaac gatggtcatc ccaagcaaaa agtaaatctc
     1981 gcctttcgca atcagcattt tttgaacagc ccaaaaaaca accaaaatgg ttaagagggt
     2041 tgaaataata tatccaacca aaatataact ttttagtttc atatttgtcc tctcggtttc
     2101 tctatcttat atcccaaccc ccaaactgtc ttaatagtgg gagtttggtc actactatat
     2161 tttgccagct cctgtcgaag agcatggata tgcacattca aggtattggt gtcatccacg
     2221 tagtcttctt tccagatctt ttcatagagg tctgtcttgg agaaaactcg ctctggattg
     2281 ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta aatccagcat ttcttctcct
     2341 atttgaactt catgactact atgattcatt tttagattgc caagggaaat cagctctgtt
     2401 tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac gcaaaaccag ctcacgtggg
     2461 ctaaaaggct tagcaataaa atcatctgct cccaagctca ggccgtaaat cttgtcctgt
     2521 tcactggtct tagcagtaat aaataggaaa ggctgctctg gtgataagta ttgaacctca
     2581 ctgattaaat cataaccatc catccgaggc atcatgacat ctgtgataat caaatcaatc
     2641 ggttttttct tgaacagctc tagcgcttcc agtccatcat gggctaccaa gacctgataa
     2701 cctgcctgaa ttaagtatct ctgatgaata tctgtgattt ctacctcgtc gtcaacgagt
     2761 aaaattgtct ttcccatctg tctctccttt gataaaaaca gtgctatact gctttaagta
     2821 taacactatt tttattgttt tacgatgatt ttaatctgct attgaaagaa agtcctgatt
     2881 gctgattgag ttgttaaact aatcttagtc agcccactat ccatcattta tttccttagc
     2941 tgattagttt tcttcttttt tgtttttcaa acctagacca ccgagtaaac ctgcaagcgc
     3001 aagcccaagg aaaccaatac ttgccattga tgtttgagtc tcaccagtat ttggtagcat
     3061 agctttatcc tctgacatca tcgtatcaga catcttgtta gcagaagcag ccatgttttc
     3121 acctgccatc gtgttggtag aacttgtcat ggtgtcagca ggcatgctat ctgtagtacc
     3181 tgtagcatga ttgtgattca tcggagtcac gccagaacca gagttagaag gtgataatga
     3241 accatttgct gtgtctgatg tttctttaac atttatctta atagtgactt ttttagttgc
     3301 tacgatgttg tccaaatctg gtttaccgtc tttgttacca tagacattga ctgtagcgct
     3361 gtaagtttga gtaccatttg ctcggaactg gtcaatgagc gcttgttttt ctttgccagc
     3421 tacatttccg tccaaggcta attgatagaa gtattgacct ttggtcttca cgttttcacc
     3481 tagtggagat agagctgggt ttttagcgtc gccgttatct gaccatgg
//
LOCUS       DAVLBN010000104         3458 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLBN010000104 DAVLBN010000000
VERSION     DAVLBN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.104"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(169..423)
                     /locus_tag="VXC24_002090"
     CDS             complement(169..423)
                     /locus_tag="VXC24_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0494132.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(443..2284)
                     /gene="typA"
                     /locus_tag="VXC24_002091"
     CDS             complement(443..2284)
                     /gene="typA"
                     /locus_tag="VXC24_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0494133.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            2446..3171
                     /locus_tag="VXC24_002092"
     CDS             2446..3171
                     /locus_tag="VXC24_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV0494134.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(3211..3408)
                     /locus_tag="VXC24_002093"
     CDS             complement(3211..3408)
                     /locus_tag="VXC24_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494135.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
BASE COUNT         1043 a          756 c          642 g         1017 t
ORIGIN      
        1 caaaataata tgcaaccagt actaaccaaa tataaaatag atgccattaa cgaattttat
       61 tcaagttttt cccattcata ctatacaagt aaaagagatg gtgttaacta aaaagcaatt
      121 caaactattg taaaattcct agcaaaaaga gagccgaaac tctctttttt atcttctttt
      181 actttttttg actggcatga gtgtgatgtc tctaacacta aagtaagcta ggatcaacat
      241 ggctattgct aggaatattt ctgttggtaa ttgaaaaatt ttcagaaaag atagaaccaa
      301 taaaatcaag agtgccacta aaatacatac catagcgacg atattgacag tccctttaat
      361 gctttctggt gtcgcaaata catagagtag gagcagtaaa attcctagga ctaaatagac
      421 catctttctc tctttctagc tcttattcag ctgatttttt cttcttgtta gctttctcac
      481 gctctgcttt gttaaggatt tgtttacgca aacggataga ctcaggcgtt acttccatgt
      541 actcatcgtc gttcaagaac tcaagagact cttcaagtgt caagatacga ggcgtcttga
      601 taacagctgt ttggtcctta gtagctgaac gaacgttggt catttgtttt gccttcgtga
      661 tgttaactgt caagtcattt tcacgagagt tttcaccgat gatcattcct tcataaacct
      721 cagtacctgg gttgacaaag atcgtaccac gttcttcgat agacatgatt gagtaagttg
      781 tagccttacc agcatcgata gaaacaaggg caccacggtg acgtccacca atttcccctg
      841 gaatcaatgg caagtattgg tcgaaggtat ggttcatgat accgtaacca cgagtcattg
      901 acaagaactc agttgagtat ccaatcaaac cacgcgctgg aacaaggaag accaaacgag
      961 tttgaccatt accagttgaa atcatatcca acatttcacc tttacgttca gaaaggcttt
     1021 ggataacaga cccttggtat tcttctggag tgtcgatttg tacacgttca aatggttcac
     1081 atttaacacc gtcgatttct tttacgataa cttctggacg agatacttga agttcatagc
     1141 cctcacgacg cattgtttcg ataaggattg acaagtgcaa ttctccacgt cctgaaacag
     1201 tccatttatc tggtgaatca gttgggtcaa cacgaaggga aacgtctgtt tgcaattctg
     1261 cctgcaagcg ttcttccacc ttacgagagg ttacccattt accttcttta ccagcaaatg
     1321 gtgagttgtt gaccaagaaa gtcatttgaa gagttggctc atcgatgtgt aggattggaa
     1381 gagcttctac tgcatctgtc ggagtgatgg tttcaccgac aaagatgtct tccatacctg
     1441 aaacggcaat caagtcaccc gctttggctt cttggatttc acgacgttcc aaaccaaaga
     1501 aaccgaagag ttttgtaaca cggaagtttt tagttgtacc gtcaagttta gaaagggtaa
     1561 cttggtcccc aaccttaact gtaccacgga agacacgacc gataccgata cgtccaacga
     1621 agtcattgta gtccaaaagc gacacttgga actgcaaagg ctcatctgag ttatctactg
     1681 gagctgggat atggtcgata atcgtgtcaa agattggtgc catagtcgct tcttggtcag
     1741 ctggatcatc tgacaatgaa gaagttccgt tgatcgctga agcataaacc actgggaaat
     1801 caagctggtc gtcatctgca ccaagctcga tgaaaagttc caagacttca tccactactt
     1861 ctactggacg agctgatggc ttatcgattt tgttaacaac cacgattggg acaaggtctt
     1921 gttccaaggc ttttttcaat acgaaacgag tttgtggcat ggttccttca taggcatcta
     1981 cgaccaagac aacaccgtca accattttca tgatacgctc aacttctcca ccaaagtccg
     2041 cgtgtcctgg tgtgtccata atgttgatac gagttccgtt gtaagcaacg gcagtatttt
     2101 tagcaaggat ggtaatccca cgctcttttt cgatatcgtt tgagtccata gcacgctctg
     2161 ccaattcagt acgtgcatca agcgtttctg attgtttcaa taattcgtca acgagggttg
     2221 ttttaccgtg gtcaacgtgg gcgataatcg caatgttacg gatatcttct cttaattttg
     2281 tcatgatttc ctctataata ttcaaaattt attttctaac tgaacgatta taccataatt
     2341 tcaaataaat aacataactc aagcaagtgt aaatgttttc actccgcttt tcttttcacg
     2401 tcaagccttt tcaaagcaag cgacttatga taagataggc acagtatgcg tttagataat
     2461 ttattagctc aagaaaaaat cagccgaaag gccatgaaac aagcactcct cagaggggaa
     2521 attctagtcg atggttgccc agcccgctcc ctagctcaaa atatcgatac aggactacaa
     2581 gaactccttt ttcaggatcg aatcattcaa ggctatgaac acacctatct tatgcttcat
     2641 aaacctgctg gtgtcgttac agccaacaaa gacaaggaac ttccgaccgt catggacctg
     2701 cttccatctg acatccagtc tgacaagctc tatgccgtcg gccgactgga ccgagataca
     2761 acaggactcc ttctcttgac cgataacggt cccttgggct tccaactcct ccatccccaa
     2821 tatcatgtcg ataagactta tcaagttgag gttaatggac ttctaacacc tgaccatatc
     2881 caagcctttc aaaagggaat tgtcttttta gatggtactg tctgtaaacc cgcaaaacta
     2941 gagattctat ctgcaagtcc ctccatcagt caagcctcta tcaccatttc agaaggaaaa
     3001 tttcatcaaa tcaagaaaat gttcctctcg gttggtgtta aggtgactag cctcaagaga
     3061 atccaatttg gggacttcac attgaaccca gatttagcag aaggtaacta ccgccctttg
     3121 aaccaaaaag agttacaaat cattaaaaac tatttagaga tgagtcgata aaataaaaaa
     3181 agctttaaaa ctaaagcttt tttcttttat ttaccgaaaa attaaggcga ttgctacaat
     3241 ccagttaact acagaaatca caattcctaa gatattaaga atcttttcta ttttatagtc
     3301 taattgtgac tctttttggt atgaaatagc caagaccaat cctatgatac ccaaaatcag
     3361 gcctacaatt ggaaataaca aaccaagaat aatcgacaag atacccacaa aaagtggatt
     3421 ttcttctttt ctttcatgtt ctaagaactc cttaaatt
//
LOCUS       DAVLBN010000105         3193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLBN010000105 DAVLBN010000000
VERSION     DAVLBN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.105"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1626
                     /locus_tag="VXC24_002094"
     CDS             <1..1626
                     /locus_tag="VXC24_002094"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0494136.1"
                     /translation="IGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYVSGSD
                     CNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIVQELF
                     LQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAILDPID
                     LVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTKRYLR
                     EGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNITDFWN
                     NRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSNNWAI
                     WLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRTLKFI
                     EKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKFYDDM
                     KPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWNYISN
                     LPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            1727..2494
                     /locus_tag="VXC24_002095"
     CDS             1727..2494
                     /locus_tag="VXC24_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEV0494137.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPIEFFNKS
                     DAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIASLFL
                     LYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEEYIN
                     RVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
BASE COUNT         1196 a          413 c          561 g         1023 t
ORIGIN      
        1 attggaggag catggccata tgcaaacggt tcgttacata ttggtcacgc ggcagcgctt
       61 ttaccggggg atattcttgc aagatactat cgtcagaagg gagaggaagt tttatatgtt
      121 tctggaagtg attgtaatgg aacccctatt tctatcagag ctaaaaaaga aaataagtct
      181 gtgaaagaaa ttgctgattt ttatcataag gaatttaaag aaacttttga aaaattaggt
      241 tttacatatg acttgtactc gcgaacagat tctccactac atcatgagat agtacaagaa
      301 ttatttttgc aattatacga gaagaaattt ttgtatacaa aaaaaattaa acaactctat
      361 tgtacatttg ataatcaatt cttacctgat aggttcgttg aaggaaaatg cccgaattgt
      421 ggaacccatt caagaggaga tcaatgtgat aattgctcag caattttaga tcctatagat
      481 ttagttgata aaagatgttc tatttgttcc aatgaaccag aagttcgtga gacagaacac
      541 ttttattatg tttttagtga gtttcaaaat ttgttagaga cttacttaaa tgatgctgaa
      601 gaaacagtga gatggcgaaa aaatgcaata aatctaacta aaaggtattt acgggaaggt
      661 ttacctgatc gagctgttac tcgtgatcta ccaaatggga ttccagttcc cattgatggt
      721 tttagagata aaaaaatata tgtctggttt gaagcggtag caggttacta cacagcaagt
      781 gttgattggg cgcaaaaact tcaaaataat attactgatt tttggaacaa tcggacaaag
      841 tcatattatg ttcatggaaa agataacatc ccatttcata ctattatttg gccggcaata
      901 ctctcaggtt tagaaataga gcctcttcca gagtatatta tttctagtga atatttaacg
      961 ttagaaaaca aaaaaatatc aacaagtaat aattgggcta tatggcttaa cgatatcata
     1021 aaaaaatatg atgctgattc aatccgatac ttcctaacaa taaatgctcc tgagatgaaa
     1081 gatgcaaatt tttcttggag agaatttatt tatagtcata actcagaatt attaggatcg
     1141 tacggtaatt ttatcaatag gactctaaag tttattgaaa agtattttga atctgaaata
     1201 cccactaaat atctcgaagg agaaatttta tataatttga aagaattata tacaacagta
     1261 ggtaatttag ttgagagcgg gcatatgaaa caggcattag aagaaatttt tgaatatatt
     1321 agatcggcta ataaattcta tgatgatatg aaaccgtggg cattgcgaga gtccgatatt
     1381 gaaaaatgta aagaagtctt agctacttgt gtaatcatta tacttaattt aggacaaatg
     1441 ttaaatccat tcattccttt ttctggtaaa aagattgagg atatgtttaa aacaaagcta
     1501 aatacttgga attatatttc aaaccttcct aacaagctat cagatgtatc aatgttgttt
     1561 gataggattg atttgaaaaa aattgacgag gaagttttag aattgcaaca aacatccagt
     1621 agataattca aaaatactcg aaagtagcct tttttaattt aaattaacaa ccggagatgt
     1681 tgaataaaat aaagatggtt ttttgagcat attatggaga aaagcattga ataatctaac
     1741 tttactaaaa gaatataatt ttagagatct tggaaaccac ctcactcaaa caggacaaaa
     1801 aataaaacct aaaacattat tccgttcaag taaactattt ggaatctcta aaattgatgt
     1861 cgatttgtta cagagctatg gaataacaaa agtcattgac tttcgatcag cgaatgaaat
     1921 aaaaaaagct ccagatccag atataaaaaa tataaaaaat atagtaattc caatattcta
     1981 taatgatgat tcagagttga cagaattccc aatagaattt tttaacaaat cagatgcagg
     2041 ttttcaacat atgataaaaa cttatgatca aatgatcaat caaaaacaga gtaaacttgg
     2101 ttacaagaaa ttctttaaat tattactaag tcatccaaaa gatgaatctc ttttgtttca
     2161 ttgttcaatg gggaaggatc gaacaggaat agctagcttg ttcttgcttt atatattggg
     2221 agtagatatg aacgatattt ttcatgatta cttactatct aacaagtatt taataaatgt
     2281 gagaaaagaa aatattgaat atgtaaataa ccatagtggg aatgtaatat tgatgcataa
     2341 tttactttca ctcagttcag caaaagaaga atatattaat cgagtattga atgtccttga
     2401 taaagaatat ggaggaatac ttagatatat taatacagaa ctaggaataa gtagtcaaga
     2461 aattgaggaa ttgaaagata gatatctttt ttagaatagt aagtactaaa aatgaatata
     2521 taacagtgcg aacggcggtt ttgtttttgt ctaattctac taatttaaca taagcaaaaa
     2581 cggattgttt tctatgtaag tccttaacta aattgatgga aagcacgtta aattatgtgc
     2641 aaaatgcgta caaaatagtg tttatcaaat gtaaaatttc ctacttgtca tcaaagttca
     2701 acaaatgtag gttgtttggt tatttgggta gatttctgga cttatcgttg gttgtagaga
     2761 cataatgttg cagttaaagc ttagagaata atctccgtat ttttgttagg caatttaaaa
     2821 gttaagacaa agtgagtttg tctcttaatt caactcacca caaacacatc acctttttat
     2881 tataacttcc gaccaatttt tttgaagaga aaaatgaaaa aacaccaact gtgcagggta
     2941 gctgacaagg cttctagctt ccatttattg aaaccaaatc aatctgttat gagataatag
     3001 cagttgcaga agctgactac tttgagaagt taaatgaggt ttattatcaa gaatacttca
     3061 tgaatatagt tataagggag ggggtagttg aaagaattga ctcatctgtt aaaataaaaa
     3121 tggaaataat aacatcataa tagtgtgact tagtattttt cagcatcttg gaagtaggta
     3181 aatgatatta aaa
//
LOCUS       DAVLBN010000106         3102 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLBN010000106 DAVLBN010000000
VERSION     DAVLBN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.106"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(285..818)
                     /locus_tag="VXC24_002096"
     CDS             complement(285..818)
                     /locus_tag="VXC24_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0494138.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(907..1683)
                     /gene="recX"
                     /locus_tag="VXC24_002097"
     CDS             complement(907..1683)
                     /gene="recX"
                     /locus_tag="VXC24_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0494139.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1721..3076
                     /gene="rlmD"
                     /locus_tag="VXC24_002098"
     CDS             1721..3076
                     /gene="rlmD"
                     /locus_tag="VXC24_002098"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0494140.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          989 a          544 c          557 g         1012 t
ORIGIN      
        1 aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat tttcgtattt
       61 tttgtattaa acgatataag tttgttgtaa acttacaagg aataaagaca ttaaaaaata
      121 acagtatatc tatttgtttt atatatttta cgaattttgc ataaatctct ttctagtaat
      181 gtgttgtaac tctgctataa tagatttatt cctttttgtg tttacacaat ttattttata
      241 ctaccaaaaa aaggtcagga ttttgttcct gacctttgac aactttaccg attctttagt
      301 tctacatagc gcttgtacca aatgtttaca taggcttctg agaaaggacc acgtccattg
      361 ttaatccaat caacaagaat tttgacatgt tcttttaaaa tatagtccaa gtcatcagaa
      421 taattcattt tgcgtttgtg acgctcgtac tcttcaacgt ccaagagacg tttttcccca
      481 tctgtaaaaa ttttaacatc caaatcgtaa tcaatatact tcagtgcttc ttcatccaga
      541 tagtaggggc tagccatatt gcaatagtaa gaagttccat tatcacgaat catggcaatg
      601 atattaaacc aatatttctt gtgaaagtaa acaatagccg gttctcgagt gacccaacga
      661 cgaccatcac tttcggtaac aagtgtatga tcgttgacac caataatggc gttttctgtt
      721 gtttttagta ccatggtgtc ccgccaagtt cggtggagac tcccatcatg cttataactt
      781 tgaattgtaa taaagtcgcc ttcttttgga agcttcataa ctaaccaact ttctacaatt
      841 tataagttta tcatttacta ttgtaccata aaattaccta aaatctgtga atttcacttg
      901 gaaatattaa agatattctc taagagcgct tgctatatcc gaaaaatcgt agccctttcg
      961 tgctaaaact tgagttaaac gctgcttcag ttcgtatcct tcatactttc gagcatactt
     1021 agtatattgc ttatcaagtt ccttgaagat gagttcttga gtcgtttctt ggtcaacttg
     1081 gctatctaag tcgtcaaagg caattttagc atcagaataa gagaagccct tgttagtcaa
     1141 gttctggata atcttatctt gcagggcacg agctggaagt tttccctcat attttttcaa
     1201 tagtttattg gctacacgtt gagcaacttc agaaaaatca aattctttca agttctcttc
     1261 tatagtagat tttgaaatcc ctttttgagc tagtttctga gtcagcacat aaggaccctt
     1321 gtctcctgaa agttgattgg tattgatgat agcataagcg tactgaccat cattaatcca
     1381 cttatcttct ttaagattag caataacttg agaaacgatg ttttcatcaa tatcgtattt
     1441 tttcagatat tctctgactt ctttttcagt gcgtgcttta aaggataagt ggtagagggc
     1501 cagattctta ccataagaaa attgagcaaa gtcttgaatc tctttcaatt cctcttcgct
     1561 tatcacctta tctctcgata acataaaacg aacaattgta tcttcggtga tatagcattt
     1621 gtcgccatta tcaagctcca tcagatagag tctttttttc ttttcaagtt ttgtgatttt
     1681 catagctcta ttataactca aaatgtgata agataggggt atgaatctga aagtgaaaca
     1741 aaaaatacca ttaaaaatca aacgcatggg aattaatggt gagggaatcg gcttttacca
     1801 aaaaacatta gtctttgtac ctggagctct caaaggcgaa gatatctatt gtcagattac
     1861 ttctattaga cgcaactttg ttgaagcaaa attactgaag gtcaacaaga agtctaaatt
     1921 tcgaattgtg ccatcttgta ctatttataa tgaatgcgga ggctgccaaa tcatgcacct
     1981 gcattatgat aagcagctgg agttcaagac ggacttactt catcaagcgc tgaaaaaatt
     2041 tgctcctgca ggatatgaaa attatgaaat tcgtccaact attggaatgc aggaaccaaa
     2101 atattacaga gctaagttac aatttcagac tcgaaaattt aaaaatcagg tcaaggcggg
     2161 cttatatgca caaaactctc actatttagt agagttgaaa gactgcctgg tacaagataa
     2221 ggaaacccaa gtgattgcta atcgcttagc agaattactt acttatcacc agattccaat
     2281 cacggatgag agaaaagttc taggtgtccg tactattatg gtccgacgcg cgagaaagac
     2341 cggacaggtt cagattatta ttgttacaaa ccgccagctt aatttaactc aattggtaaa
     2401 agagttggtt aaagatttcc cagaagttgt gacagtagct gttaatacaa atacagctaa
     2461 aaccagtgag atatatggtg aaaagacaga gattatctgg gggcaagaga gtattcaaga
     2521 aggtgtactc aattatgaat tttcactatc ccctcgagct ttttatcaac taaatcctga
     2581 gcaaacagaa gtcctctata gcgaagcagt aaaagcgctg gatgttgata aagaagacca
     2641 tttgattgac gcttattgtg gagttggaac gattggattt gcctttgcaa agaaagtaaa
     2701 aacactcaga ggtatggata ttattccaga agctattgaa gatgccaagc gaaatgctaa
     2761 aagaatggga tttgacaata ctcattatga agctggaacg gcagaagaga ttattcctcg
     2821 ttggtacaag gaaggctacc gagcagatgc tttgattgtt gacccaccac gtacaggtct
     2881 ggatgataag ttattagata ctattcttac ttatgtacca gaaaaaatgg tttatatttc
     2941 ttgtaatgtt tcgaccttgg ctcgtgattt ggtacgctta gtagaagtct atgatcttca
     3001 ttatatccag tcggtcgata tgttcccaca tacagctcga actgaagctg ttgtaaaatt
     3061 aataaaaaaa gtttaaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DAVLBN010000107         3100 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLBN010000107 DAVLBN010000000
VERSION     DAVLBN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.107"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..370)
                     /locus_tag="VXC24_002099"
     CDS             complement(<1..370)
                     /locus_tag="VXC24_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0494141.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINR"
     gene            464..1684
                     /locus_tag="VXC24_002100"
     CDS             464..1684
                     /locus_tag="VXC24_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEV0494142.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1697..2878
                     /locus_tag="VXC24_002101"
     CDS             1697..2878
                     /locus_tag="VXC24_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0494143.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT         1053 a          416 c          640 g          991 t
ORIGIN      
        1 gacgattaat ctgttgttca gcaatcaatt ttatgtgata attgcataaa cttttttctt
       61 gcttttgttt taactctatt ttatccacta attcttgaag taaaaatata tctgaagaat
      121 ttacagcatg ttctaattct tcaaaaagac attctttttt ggaataataa caatgaacta
      181 attcttcaaa ttctgaaaat gatattccaa gacggtttaa cagaatataa aaatgattaa
      241 tagataattt tgtaatgcca ttttcgaaac gagaaatagt tgattcacta atttcattac
      301 atgataaatc tttaaggcga aaattttttg aaatacgaat atcctttaaa actgctccga
      361 aattttccat aatgttcctc ttccatttct gcaaaaaata aaacgcttgt tttttattta
      421 tgatatgatt atacaaaaat aaaatagaaa ggacaataat atcatgaaaa aaattttatt
      481 gtcaacagtt gctttattaa gcttagtagc atctctgcta gcaaataatc cagtttctgc
      541 tcaagaatca tcctctcaag caacttatag taagtcaagt ggaagttgga taaaatctgg
      601 taaccgttgg tggtataagc attctgatgg ttcttatact acaaatggat gggaaaaaat
      661 aaatggtacc tggtactatt ttgatagtga aggttggatg aagacaggtt ggattaaaga
      721 atatgggaaa tggtattacc tagatgatag tggtgctatg aaaactggat ggtgtttggt
      781 ttctggtagc tggtattatt taaatagtag cggtgtaatg caaacgggac tacagactat
      841 caatggaaaa caatattatt tagctgccgg cggtgctatg cagacaggtt ggcacaatat
      901 cggagatgat acctatttct ttgctaatag tggggaaaat caaaatatca atcgtcgtgc
      961 tttagttctt ggtgaaacat caacgagagc agtacctatt gcagatgtta atgctatgga
     1021 aaaggttttt aataaccaaa actttagtga agttgttcgt ttcccagata gaacaaaatc
     1081 cgagataatt gcaaaaatgc aagagctttt tgaatcttct agcgaaggcg atgtgaacta
     1141 tctttacttt acttgtcatg gaggaagaga tggaagaatc tatattggta gtgatggcct
     1201 agcattttct ggttgggaat tggcgtccgt tttgaaacaa tacaaaggta agtttgttgt
     1261 tatgctggat tgttgtcatg ctggaacaat tatttctaaa gataatacag gtgaaggcaa
     1321 tgaaggagcc tctacggaat attttgattt agatgaattt gtatcaggat tttctaatat
     1381 ggatggtaac gaaaaatcag gtgagatgat tgactctaaa tttttagtat tatgctcatc
     1441 aagaggtgca gaatactcta gtggtggatc attaagttta gcgactaaat attggtcttt
     1501 aggttcagga tggaatcctc tacagaattc acaagcatat ttagcagcag accaaaataa
     1561 taatcgcaga atcacattaa atgaattgta tacatactct cgtgaacaag ttttgaaaca
     1621 aaattctaac cagcatattg aagtttatcc tgacaacagt caatttgtgt tatttaagaa
     1681 ataagggggc aataaaatga aagtatcaaa aaaaattaca ctatttagtt tgtcttttgc
     1741 aggttttgtt ttattgactt tacctcaagc aggaaaggct tttgaactta aagaagactg
     1801 ggcatttaaa ggtggcattc gatacgagaa tgggaaagtc agcaaaatta ataatggata
     1861 tgaagtaaat attaaagtgt tagatttacc tagtactagc gcaatcgaat ggacagttag
     1921 attgaatgga gaaaagcaaa atactaactt cttagcggag gaaagaactg tatctaaaac
     1981 tgaagataag ggacgtttct tgcactttta tatcccctat ggatatcgtg gggatattgt
     2041 agtagaggct aagagtggaa acgaagtgaa gacttggtct actaaggtag ttgacgatgt
     2101 ttattcagat tctgctaaga gtggctactt tattctcgat ggggaacaaa tcttagaaag
     2161 ttcatgggat tccgtaaatg agtcttatat tgcaacgctt ccaactgtaa catcaggaaa
     2221 aactgttgtt gcttggcgtg aaaaaggaac tcttaattta attaaaccag gaagaattgc
     2281 tcggcaatat aatagcagtg gatcatatgt agaactttct ccaatctttg aaactgctag
     2341 ttggctaaaa tcaaaccaaa actggtacta tcaaaaacaa ggtcaattag ttcaaaattc
     2401 ttggatcaag gatcagggaa gctggtactt tatggatgat gaaggggtta tgtttaatca
     2461 aacatggcta caccaaggtg gaagctggta tgcctttaag tcatcaggag ccatgatttc
     2521 agctgattgg ttgtatgata atggttcttg gtattaccta aaggactcag gttctatggt
     2581 aacaggatgg cttaaaaatg gaggctcttg gtattaccta aacaagtcag gttcaatggc
     2641 tacaggttgg attaaagata gtggaacttg gtattatcta aagaattcag gctctatggc
     2701 gacaggctgg gtgaaagata gtggctcttg gtattatcta aagaactcag gttcaatggc
     2761 aacaggttgg gtcaaagata atggtaagtg gtactatctc gcatcatctg gtaatatgct
     2821 tcgcaataca cgcacaccag atggctatta tgtagatggc agtggcgctt ggaaataaat
     2881 ttttaaaaga gaaaatctac tgagaaggta gattttcttt ttagttaatg aatatagaat
     2941 aaagtagatc aggactggtc tattttattt tgtaactatt aatgaatagt cttaatgatg
     3001 aagttacttt ctgaagatat ttaattgtgt tgagatttga taaaactata gcggattgaa
     3061 ataagatata aacaaagaga ttatggaagt caaattaatt
//
LOCUS       DAVLBN010000108         2894 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLBN010000108 DAVLBN010000000
VERSION     DAVLBN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.108"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            81..311
                     /locus_tag="VXC24_002102"
     CDS             81..311
                     /locus_tag="VXC24_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0494144.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            540..2798
                     /locus_tag="VXC24_002103"
     CDS             540..2798
                     /locus_tag="VXC24_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0494145.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT          916 a          603 c          597 g          778 t
ORIGIN      
        1 cgagaaatct tagttttttc tagtcaagtt ggcctccttt atggtaaaat agtaacgata
       61 agaaatgaag gagaatcaaa atggaatcac atttggttag aatcatcaac cgccttgaag
      121 caatggcaaa cgatggcgga aatttaaaac gtaattttga acgcgaagga gttgttgttg
      181 cagaagttgc gtacagccac gacgaagaaa acggcccaat ctttaccctt cgtgacgtag
      241 aagatcgcga aacgtatacg tttgatagca ttgacttaat cgcaatggaa atttacgaac
      301 ttctctacta atctaaaaca agctgggatt gtccctgcat gtctaagtaa aatccttttt
      361 gtctcacaaa taggattttt ttatagtcca aattcacaaa aattttcatt gtaacaactt
      421 ctcaaagctt caatcttttt acttgcttta caccccaatc ctgttataat gagagtatag
      481 aatttgacta tttttgacct ttaaacaagt caggctaaag aaagaaatga ggtagatgta
      541 tgctttgtca aaactgtaaa attaacgact caacaattca tctttacacc aatctcaatg
      601 gaaaacaaaa acaaattgac ctctgtcaaa actgctataa gattatcaaa acagatccta
      661 acaatagcct cttcaaaggt atgacggatc tgaacaatcg tgacttcgat ccctttggtg
      721 atttcttcaa tgatctaaac aatttcagac cttctagcaa tactcctcct attcccccaa
      781 cccaatcagg tggaggttac ggtggaaacg gcggttatgg ttcccaaaat cgtggatctg
      841 ctcaaactcc gccacctagc caagaaaaag gcctgctgga agaatttggt attaatgtaa
      901 ctgaaattgc ccgtcgtgga gacattgacc ccgttattgg gcgcgacgat gagattatcc
      961 gtgtcatcga gattctcaat cgtagaacca agaataatcc tgtccttatc ggtgaacctg
     1021 gtgtcggaaa aacggccgtt gtcgaaggtc tagctcagaa aattgtcgat ggcgatgtgc
     1081 cacataaact ccaaggtaaa caagtcatcc gtctggatgt ggttagctta gttcaaggaa
     1141 cggggattcg aggacaattt gaagaacgca tgcaaaaact catggaagaa attcgcaaac
     1201 gtgaagacat catcctcttt atcgatgaaa tccatgaaat tgttggtgct ggttctgcga
     1261 gtgatggtaa tatggacgca ggaaatatcc tcaagccagc ccttgctcgt ggagaactgc
     1321 aactagtcgg tgctactacc ctcaatgaat accgtatcat tgaaaaggat gctgccctcg
     1381 agcgtcgtat gcagcctgtt aaagtcgatg aaccaacggt ggatgaaaca atcactattc
     1441 tcaaagggat tcaaaagaaa tacgaagatt accaccacgt tcaatatacc gatgctgcga
     1501 ttgaagcagc tgcaactctt tccaatcgct acatccaaga tcgcttcttg cctgacaagg
     1561 ccattgacct cctagatgaa gctggttcta agatgaactt gaccttgaat tttgtggatc
     1621 ctaaagtaat tgatcagcgc ttgattgagg ctgaaaatct caagtctcaa gctacacgag
     1681 aagaagattt tgagaaggcg gcctacttcc gcgaccagat tgccaagtat aaggaaatgc
     1741 aaaagaaaaa gatcacagac caggatactc ctatcatcag cgagaaaact attgagcaca
     1801 ttatcgagca gaaaaccaat atccctgttg gtgatttgaa agagaaagaa caatctcaac
     1861 tcatccatct agccgaagat ctcaagtctc atgttattgg ccaagatgat gcagtcgata
     1921 agattgccaa ggctattcgc cgtaatcgtg tcggacttgg tacccctaac cgcccaatcg
     1981 gaagcttcct cttcgttggg ccaactggtg tcggcaagac agaactttcc aaacaactgg
     2041 ctatcgaact ttttggttct gctgatagta tgattcgctt tgatatgagt gaatacatgg
     2101 aaaaacatag tgtggctaag ttggtcggcg ctcctccagg ttatgttggc tatgatgagg
     2161 ctggtcaatt aactgaaaaa gttcgccaca atccatattc tctcatcctt ctcgatgaag
     2221 tggaaaaagc tcacccagat gttatgcaca tgtttcttca agtcttggac gatggtcgtt
     2281 tgacagacgg gcaaggacgc accgttagct tcaaggatgc tatcattatc atgacctcaa
     2341 atgcaggtac aggaaagacc gaagctagcg ttggatttgg tgctgctaga gaaggacgta
     2401 ccaattctgt cctcggtgaa ctcggtaact tctttagccc agagtttatg aaccgttttg
     2461 atggcattat cgaatttaag gctctcagca aggataacct ccttcagatt gtcgagctca
     2521 tgctagcaga tgttaacaag cgcctctcta gcaacaacat tcgtttggat gtaactgata
     2581 aggtcaagga aaagttggtt gacctaggtt atgatccaaa aatgggagca cgcccacttc
     2641 gtcggactat tcaagactat attgaggaca caatcactga ctactacctt gaaaatccaa
     2701 gcgaaaaaga tctcaaagca gttatgacta gcaagggaaa cattcagatt aaatctgcca
     2761 aaaaaactga agttaaaagt tctgaaaaag aaaaataaat cctataaaaa aagagtagaa
     2821 aatgaaattt ttctgcttct ttttttacta aaataactgt aatttcttga cagcttgccc
     2881 tttgtccatt atga
//
LOCUS       DAVLBN010000109         2870 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLBN010000109 DAVLBN010000000
VERSION     DAVLBN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.109"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..876
                     /locus_tag="VXC24_002104"
     CDS             <1..876
                     /locus_tag="VXC24_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0494146.1"
                     /translation="MKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLK
                     KFDIDLKDVEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDK
                     GQILIDVKDIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKL
                     ANCTDFIEKMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVN
                     NEKKIQESLNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIY
                     KNLIEKTKMAEEFIY"
     gene            887..1471
                     /locus_tag="VXC24_002105"
     CDS             887..1471
                     /locus_tag="VXC24_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0494147.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1471..2166
                     /locus_tag="VXC24_002106"
     CDS             1471..2166
                     /locus_tag="VXC24_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0494148.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            2154..>2870
                     /locus_tag="VXC24_002107"
     CDS             2154..>2870
                     /locus_tag="VXC24_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494149.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSL"
BASE COUNT         1040 a          364 c          550 g          916 t
ORIGIN      
        1 atgaagataa aagactcttt agatgcatct aaagagggct tgatggaaat attttattta
       61 tcgcccaaaa tagaaagatt aaaagaaatt caaaatcaag atttacaaga aggcgatgac
      121 tatagcttaa aaaaatttga tattgatcta aaagatgttg agtttgccta caataaagac
      181 gcaaaagttt taaatggtgt aagttttaaa gctaagcagg gagaggtcac tgctttggta
      241 ggtgcaagtg gctgcggtaa aacaactatc ttgaaactta tatcaagact ttatgattat
      301 gacaagggac aaatcttaat cgatgtcaaa gatataaaag aaatatcaac agaatctctt
      361 tttgataagg tctctatagt tttccaagat gtggttctct ttaatcaaag cgttatggaa
      421 aatattagaa tcggaaagca agatgcaagt gacgaagagg ttaaaagagc agcaaaactt
      481 gcaaattgca cagattttat agaaaaaatg gataaaggtt tcgatacagt tattggtgag
      541 aacggagctg agctatcagg aggagaaaga caaagattat caatagccag agccttctta
      601 aaagatgcgc cgatattgat cttagatgag ataacagcaa gccttgatgt taacaacgag
      661 aaaaagattc aagagtcttt aaataattta gttaaagata aaactgttgt aatcatttca
      721 catagaatga aatccataga aaatgcagac aagatagtag ttcttcaaaa cggaagagta
      781 gaaagcgaag gtaagcatga agagctttta caaaaatcaa aaatttacaa aaatttaata
      841 gaaaagacaa aaatggcaga agaatttatt tattaggagg actacaatgg ataataaaaa
      901 attaaaagta aaagatttag taagtatcgg tgtttttggc gtaatttatt ttgccttcat
      961 gtttggagtt ggtatgatgg gcttgattcc aatattgttc ttaatatacc cgacagtatt
     1021 agccatagtt gcaggaactg ttgttatgtt atttatggct aaggttcaaa agccatgggc
     1081 actatttata tttggtatga tatcaccact tgtgatgttt gcagctggtc atacctacgt
     1141 agttgtggtt ttatcactta tagtaatgat aatagcagaa ttaattagaa agattggtaa
     1201 ttataattca tttaaataca atatgctttc ttatgcaatc ttcagcacat ggatatgtag
     1261 ctctttaatg caaatgcttt tagcaaaaga aaaatatatg gagtggtctt tgatgacgat
     1321 gggaaaagat tatgttgatg tattagaaaa gttaataact tatcctcaca tggctttagt
     1381 agccttaggt gctttcttag gaggaattct tggagcatat ataggcaagg ctctattgaa
     1441 aaaacacttt gaaaaagcag gcatcgtata atgcctactt tttcttcaaa tgctcccttt
     1501 aatcccaatc cgatctctaa gatattagtc gtatttatca caggcttaac tgttatgcat
     1561 agcataaaca tccgttttga gctggcaatt gtttgtctta ttggtatttt gctttatttg
     1621 aatggataca aaaaaacact tttcaaatgg attatattgt gtgggatact ttactccttg
     1681 cctaatttta tggtgttatc tgaattaaac cctatagtta agatgttttt gagtatacct
     1741 attgttatta gaatgtttat tttaccattt atggcagcaa gctttatgat aaagacctcg
     1801 gatgtaggcg caataatttc atcgatggat aagcttaaga tttcaaagaa tgtatccata
     1861 cctattgcgg ttatgtttag attcttccca tcttttaagg aggagaagaa aaacatcaaa
     1921 atagctatga gagtaagagg gataaatttt aaaaacccag tcaaatatct tgaatatgtt
     1981 tctgtgccac tactcattat atcatctaat atatcagatg acattgcaaa agcggcagaa
     2041 acaaaggcaa tagaaaatcc aattgccaag accagataca ttcgcgtaaa gatacagcta
     2101 attgattttg tttatgtttt agcggttgct ggacttattg tgggaggctt aatatggttg
     2161 aaataaaaaa tttaagtctt gattatggtg aagagcatat attagatgat atatcactat
     2221 ccatagccga gggagagtgc gtgctattta caggaaaaag tggaagtggt aagtcatctt
     2281 taataaattc aatcaatgga ctagctgtaa ggtatgataa cgcaaagaca aagggcgaaa
     2341 taattattga tggtaagaat ataaaaaatt tggaacttta tcaaatctca atgcttgttt
     2401 caactgtttt tcaaaatcct aagacatatt tttttaatgt caatacgaca ttagaattat
     2461 tattttattt ggaaaatatc ggtcttgcaa gagaagagat ggacaggcgt ttgaaggata
     2521 tgcttgagat attcccgata aaaaatcttt tgaacagaaa tatatttaat ctatccggcg
     2581 gtgaaaaaca aattctttgc attgcagctt cttatatagc aggtacaaag attatagtta
     2641 tggatgagtc ttcatcgaat ttagatatta aaagcataag tgttttggca aagatgctaa
     2701 agatattaaa agagaaaggc ataagcataa ttgttgcaga gcatagaatt tattatttga
     2761 tggacatagt tgaccgtgta tttttaatag ataaaggaaa gcttaaaaaa acttatacta
     2821 gaagtgaatt tttaaagcta gataaaaatg aattaaatgc tttaagttta
//
LOCUS       DAVLBN010000110         2840 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLBN010000110 DAVLBN010000000
VERSION     DAVLBN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.110"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..153)
                     /locus_tag="VXC24_002108"
     CDS             complement(<1..153)
                     /locus_tag="VXC24_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0494150.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRH"
     gene            358..546
                     /locus_tag="VXC24_002109"
     CDS             358..546
                     /locus_tag="VXC24_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0494151.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            703..1068
                     /locus_tag="VXC24_002110"
     CDS             703..1068
                     /locus_tag="VXC24_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0494152.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            1071..2738
                     /locus_tag="VXC24_002111"
     CDS             1071..2738
                     /locus_tag="VXC24_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0494153.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          904 a          517 c          627 g          792 t
ORIGIN      
        1 gtgtctgaaa gcttcttttc ctttctgttg ataggctagt agcagacgat tgatttgtct
       61 ttcagaaaga ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc
      121 ttttatcaca agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact
      181 attctaccaa atgtgacatt ttcacgttcg atttactaaa gacattatca cattcgaatc
      241 acaacacaaa taaaaaatct tccaattccc ttgcaaaaaa caagaaagtg tgataacata
      301 gtacggtatg tggtgctagc acatccgcta tattagatct aataggagga aaacacaatg
      361 gctaaagtat gttactttac aggtcgtaag actgtatcag gaaacaaccg ttcacacgcg
      421 atgaaccaaa caaaacgtgc cgtaaaacca aaccttcaaa aagttactgt tcttatcgat
      481 ggtaaaccta aaaaagtttg ggcttcagct cgtgctttga aatcaggtaa agttgaacgc
      541 gtttaataat aaaagcaaag gagaccttag ggtctttttt cttttattgt gggtataaca
      601 tcgtttgaaa aatagagtaa atatccgctg atacatcatt ctgcttttac acttgggctg
      661 aaatatgata aaatagagta tcaactagtt gaggtaaaaa ggatgactgt aaaaattaat
      721 acaaaagatg gtcaaatcga actaacagat gaagtgattg caaccgtcgt aggtggagca
      781 gcaactgaga tttttggtgt ggtcggtatg gctagtaaaa atgccctcaa agataatttc
      841 caagccctgc taggtaagga aaattattct aaaggtgtcg tcgtaaaggc agccgaagat
      901 ggcagtattg cagttgatgt atataccgtg ttaagctacg gaacaaagat tagtgaagtg
      961 tcaaaaaaca ttcaagagcg tgttgccttt agcttggaaa accagcttgg aattactgct
     1021 cagactgtaa atgtctacat tcaaaatatc aaagttgtag gagaataacc gtgtcaaaga
     1081 ttactactag cttatttcaa gaaatggtgc aggctgcatc aactcgcttg aataagcaag
     1141 ctgaatatgt caattcatta aacgtctttc cagttccaga tggagatact gggacaaata
     1201 tgggaatgac cattgaaaat ggtgctaaag aagttgcaga caagccagct tctacagttg
     1261 gagaagtagc gagcattctt gccaaagggc ttttgatggg tgcgcgtggg aactcaggag
     1321 tgattacatc tcagcttttc cgtggatttt cccaagctat caaggataaa gacgagttaa
     1381 caggtcaaga cttggctctg gccttccaat caggtgtgga agttgcctat aaggcagtga
     1441 tgaaacctgt tgaaggaacg attttgacag tttctcgtgg agctgctatc ggtgctaaga
     1501 aaaaagctga gcaaacagat gatactgttg aagtcatgcg cgcagccttg gaaggtgcta
     1561 aaacagctct agctaaaaca ccagacatgc ttccagtatt gaaagaagtt ggcgttgtgg
     1621 actcaggtgg tcaaggattg gtcttcatct acgaaggttt cctttcagcc cttactggcg
     1681 aatatattgc atctgaggac tttgtagcga ctcctgccaa catgagtgag atgatcaatg
     1741 tagagcatca taagtctgta gctggtcacg tagcgactga ggacatcacg tttggttact
     1801 gtactgaaat catggtagct cttaagcaag gtccaaccta tgctaaagat tttgactacg
     1861 atgaattccg taactacttg gatgagcttg gggattctct cctcgttgtt aacgatgatg
     1921 aaattgtcaa agtccatgtt catacagaag atccaggact tgttatgcaa gaaggtctca
     1981 aatatggtag cttggtcaag gtaaaagttg acaatatgcg taaccaacac gaagcacagg
     2041 ttgagaaaga agctactcaa gttatcaagt cggctgaaga aaaagagtat gctttgattg
     2101 ctgtggtggc tggtaaaggt ctagcagata tcttctgttc tcaaggcgtg gattatgtta
     2161 tcgaaggcgg tcaaaccatg aacccttcaa cagaagactt tatcaaggct gttgaacagg
     2221 tcaatgcccg taacatcatc ttcttgccaa acaacaagaa catcttcatg gcagctcaat
     2281 ctgcggcaga agttttggag caaccagcag tagtggtaga ggctcgcact cttcctcaag
     2341 gtatgacaag tcttcttgcc tttgatccaa gcaagtccat tgaagaaaac caagagcgta
     2401 tgacagctgc tcttagcgat gtcgttagcg gaagcgtcac aacagccgtg cgtgatacaa
     2461 cgatcgatgg cttagaaatc catgaaaacg ataatctagg tatggtggat ggaaaaattc
     2521 ttgtgtcaaa ccctgatatg caccaaacat tgactgaaac cttgaaacat atgttggatg
     2581 aagacagtga aatcgtaacc ttctatgtcg gtgaagacgg aagcgaagaa cttgccaatg
     2641 aaatcgctca agaaatcgta gaagaattcg aagacgttga agtcgagatt caccaaggtc
     2701 aacaacctgt ttacccatac ctatttagtg tggaataaga ttaatgaagg actgagaaat
     2761 cagttctttt ttctttttta gtaaatgaaa tcggtatctt tttaataaaa acaaaaataa
     2821 cattcataaa taaacgttaa
//
LOCUS       DAVLBN010000111         2784 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLBN010000111 DAVLBN010000000
VERSION     DAVLBN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.111"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>2784
                     /locus_tag="VXC24_002112"
     CDS             <1..>2784
                     /locus_tag="VXC24_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0494154.1"
                     /translation="RYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVD
                     TSYSEAPEDIEGQISTVESTFKQRVNSLEAGVNRLTEGLRTKADISALNVTAENIRQS
                     VKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSK
                     MKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKV
                     TFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYI
                     TFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENEL
                     LVAKTEFKRTADGLSTKMAAVESYVGQDGQRQEALQRYTREESTRQATAVRELVNRDF
                     VGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVG
                     GQISGLSNRLTSSEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMG
                     RISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKV
                     ARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKD
                     LMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFT
                     IVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGY
                     KPRTWQPHPEDAVADANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNR
                     FVGKLTHITGETLIDRAVIKSAMVDKLKTGNFEAGSVTTTILDAEAVTAEKLKVDDAL
                     IRKLTANDAFIDRLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWIS
                     GVNQFSVGMGNGAG"
BASE COUNT          915 a          501 c          648 g          720 t
ORIGIN      
        1 cgatatgttg tccatattcc aaaaggttgg acaaacgaat ccaagcagac cacaaatgaa
       61 tggttgttca atttcaacca ggaaggaacc gtttggattt ggatgccgaa gtttgaaata
      121 agcgatgtag atacttctta ttcagaagct cctgaagata tagaaggtca gatttcaaca
      181 gttgaatcga cctttaaaca acgagtcaac tcgctcgaag ctggtgtgaa tcgtctgact
      241 gaaggcctta gaaccaaagc cgatatcagc gcactcaacg tgactgctga aaatatccgg
      301 caatctgtga agagtcttga gacagacacg cagaacaagc taaatcagaa gttgagtcag
      361 gctgaatttg aggtgcgagc cggctctatc cgtcaggaaa tcctgaacgc aaccaaggat
      421 aaggcagata agactttagt tgtatctgaa gctgggaaat tgcgtgaaga attttcaaaa
      481 atgaaggtgg gaggccggaa tctatggata aaatccaaga cggttggagc tgtaattgaa
      541 aaattacctg aaaaccatgt cacaggtcaa aaagaatgtt ataggttaga gaacaactct
      601 actttaacgt tcaaccttga accagatttc agctcaaggt tgtatcaaaa agttactttt
      661 agcgcttgga tcaagtacga aaatgtagtc caaggtcgaa acttttggaa tgtatttaat
      721 tgcttcaaac attatctttt tagaaaaaat agtgagaccg gagtacagag tggtccagat
      781 tatgctacgc ttggtatgta taaaggttcg gcagattgga aatatattac attcacttat
      841 gactactctg aaaaaacaaa ttttgatcaa ttgaagacat cattgcgatt caatcttgaa
      901 ggtgctacaa gcggtacagc ttgggtaaca ggaatcaagg ttgaaatcgg tagtgtggcg
      961 acggactggt caccagcacc agaagacgga gaaaatgagc ttttagtcgc taaaaccgag
     1021 ttcaagagga cagctgatgg cctatctact aagatggcag cagttgagag ctatgttggt
     1081 caagacggtc agcgacagga agccctacag cgctatactc gtgaggaaag cacgagacaa
     1141 gcgacagcag tccgtgagct ggtcaatcgt gatttcgttg gtaaggctac ttatcaagaa
     1201 gatgttaagg gtatcaatca gaggattgaa gctgttaaaa ctagtgcgaa taaagacatc
     1261 gctagtcaaa tcgctagcta tcgtcaatct gtagatggta agttcacgga tatttcaagt
     1321 cagataacta cttataagca agatgtgggc ggtcaaatca gtggtctatc aaatagactt
     1381 acaagcagtg agcaaggaac cactactcag atttcaaata tttcaaatcg gataaacagt
     1441 aataagcaag gcacagataa tcagatttca aatttaaaga ctcaggtcgc tacaaacaag
     1501 gataatgctg aacgacaaat gggtagaata tctgatcagg tttctgcaaa caaagcgaat
     1561 gctgatagtc aatttgcgaa tgtgaccaat caactagcgc gaaaagtaga gactactgac
     1621 ttccagcgtg ttaaggaaac cagtaaactt tacgagcgaa ttttgggcaa tactgaaaat
     1681 ggaattgcgg ataaggttgc tcgcatggct ctgactaatc aactgtttca ggttgaggtt
     1741 gggaaatata gtgtaagcgg ccctaacctc attaagaata gtgattttaa aaatgctacg
     1801 aatgaatggg gctcaactca aaatttagga agattggtta agcatagctt ttatcacaac
     1861 gggcagaaag accttatgcg tttaagtaat gcaactaaaa acgaaaactt tttgtatagt
     1921 caccgtttta atcttgaacg aaatactgac tatgtactga attttagagg atttaacaac
     1981 agtgctctcg caagctatga tgtttatatt ttgggacgaa gagcaggcga gagcgatgga
     2041 ttcacaatcg ttaagaaagt tgttagcagc aagaaactat ctacctctag atgcgaagat
     2101 gtctcagtaa cttttaattc cggagaaatg gataatgctt acattcgttt tgataacaat
     2161 ggctcatcat caggaacagc tgatttgtat attacagaag ttgacttgta caaaggttat
     2221 aaacctagaa catggcaacc acatccagaa gatgcagtcg cagatgcgaa taagaagctt
     2281 gaagcaacgc aaacaaaaat gactcaacta gctggctcat gggtagttga aaacatcaac
     2341 tcggctggag atatcatctc tggaatcaat cttggcgcca atggacataa ccgcttcgtt
     2401 gggaaattga cccacatcac tggagagacc ctgattgaca gagcagtcat caagtctgcc
     2461 atggttgata agctgaaaac gggcaatttt gaagctggtt cggtcacgac tacgatatta
     2521 gacgctgaag cggtaactgc tgagaagttg aaagttgacg atgcgcttat tagaaaatta
     2581 actgcaaatg atgcttttat tgaccgactg acatctaaac gtatcttctc tactaaggtt
     2641 gagtccgtca tttctagttc aaccttccta gaagcctatc aaggtcgaat tggtggattc
     2701 acacttggtc aatttgacca gggtggcggt cgctggattt caggtgtcaa tcagttctct
     2761 gttggtatgg ggaatggtgc cggg
//
LOCUS       DAVLBN010000112         2570 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLBN010000112 DAVLBN010000000
VERSION     DAVLBN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.112"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            59..1813
                     /locus_tag="VXC24_002113"
     CDS             59..1813
                     /locus_tag="VXC24_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494155.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1797..>2570
                     /locus_tag="VXC24_002114"
     CDS             1797..>2570
                     /locus_tag="VXC24_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494156.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVI"
BASE COUNT          916 a          342 c          470 g          842 t
ORIGIN      
        1 tattatcaat taagcgaatt tatatctaaa agggatatta aagaaaggag atatgcttat
       61 gaagatttac aaaaaactat ttgcttatgt ccaagataag aaatatcttg gggttttggc
      121 cataattttt tctgctatat ctgctctact tacagtatat ggatattatt taatctacaa
      181 atttctagat aagttaataa ttaattcaaa tttatccggt gcagagagta tagcattaaa
      241 atctgttatt acactaacaa gtggagcgat attttatttt gtctcaggaa tgttttcaca
      301 catcttggga tttaggcttg aaacaaattt aagaaaaagg ggaattgatg gcttagagaa
      361 agcaagtttt aggttctttg acttaaatcc atctggtcaa ataagaaaga tcatagatga
      421 taatgcagca caaactcatc aggtggtagc acacatgatt cccgatagtt ctcaggcaat
      481 aatcacaccc gtacttgtac ttgcacttgg ctttatagta agtataagag ttggcataat
      541 tttgcttgct cttactataa ttggcggctt aattttaggg gcaatgatgg gcgagcaaga
      601 atttatgaag atataccaag aatccctatc taaactaagt gctgaaactg ttgagtacgt
      661 gagaggaatg caagttgtaa aaatatttaa agcaaatgta gagtctttta aaagctttta
      721 taaggcgata aaagattact caaagtatgc ttatgattat tccctatctt gtaaaaggcc
      781 ttatgttttg tatcaatggt tattttttgg actgattgca attttaatta ttcctatagt
      841 ttattttatg actagcttag ctagcgcaaa ggtgatttta cttgagctta tcatgatttt
      901 atttttatca ggagttctct ttgtttcatt catgagaatg atgtggtact ccatgtatat
      961 ttctcaagga aattatgcag tagatacttt agaggcgctt tacgaagata tgcaaaaaga
     1021 caaattagtg catggtaata tcaataattt taaaaactat aatatagaat ttgagaatgt
     1081 tagctttgct tataatgata aagctgtcat tgaaaattta tcctttaatt tagaagaagg
     1141 aaagtcctac gcacttgtcg gttcatctgg atcaggcaaa tcaacagtag caaaacttat
     1201 atcaggtttt tataatgtta ataaaggaag cataaagata ggcgggatag caataagtga
     1261 atattctgac gaagccttaa ttaaagccat ttcctttgtt tttcaagatt caaaattatt
     1321 caagaagagc atttatgata atgtagcttt agctaataaa gatgcgacga aagatgacgt
     1381 tatgagagcc ttaaaattag caggatgcga tttaatatta gacaaattcc cagaaagaga
     1441 aaatacaatc ataggctcaa aaggtgttta tttatccggt ggagaaaaac aaagaattgc
     1501 aattgctaga gcaattttaa aggattccaa aattattatt atggatgaag catcagcatc
     1561 tattgaccca gataacgagt ttgaattgca aaaagctttt aaaaatctta tgaaggataa
     1621 aacagttatc atgattgcac acaggctatc tacaattaaa gaccttgatg aaattattgt
     1681 catggatagt ggaaaaatta tagaaagagg gtctgacaaa gaattaatgt caaaagatac
     1741 aaggtataag agcctgcaag agatgtttaa cagtgcgaat gaatggaggg tttcaaatga
     1801 aagagtttta taaaaaaaga tttgctctta cagatggagg agcaagaaat ttaagtaaag
     1861 caacactggc ttcatttttc gtttattgta taaacatgct tcctgccata ttacttatga
     1921 tttttgctca ggaagttttg gaaaatatgg gcaaaagcaa tggcttttat atagtattct
     1981 cagttttgac tttgatagca atgtatattt tgctttctat cgaatacgat aaattatata
     2041 acacaaccta tcaagaaagt gcagatttaa gaataaggac agcggagaat ttatcaaaat
     2101 tacctctatc ttacttttct aaacatgaca tttccgacat ttcacaaaca atcatggctg
     2161 atattgaagg catagagcat gcaatgagcc actcaatacc aaaggtgggc ggcatggtac
     2221 tgtttttccc attaatatct gtaatgatgc tagcgggcaa tgtcaagatg ggtttagctg
     2281 taattattcc atctatttta agctttatat ttataccttt atctaaaaaa tatcaggtta
     2341 atggacagaa tagatattat gatgtcttaa gaaaaaactc agaaagcttt caagaaaata
     2401 tcgaaatgca aatggagatt aaagcatata atttatcgaa ggatattaaa gatgacttat
     2461 ataaaaaaat ggaagatagt gagagagtac acttaaaggc ggaagtaact acaattttaa
     2521 ctttgtctat atcttcaata tttagcttta tatctcttgc tgttgtgata
//
LOCUS       DAVLBN010000113         2534 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLBN010000113 DAVLBN010000000
VERSION     DAVLBN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.113"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            112..1458
                     /gene="gdhA"
                     /locus_tag="VXC24_002115"
     CDS             112..1458
                     /gene="gdhA"
                     /locus_tag="VXC24_002115"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0494157.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(1747..2505)
                     /locus_tag="VXC24_002116"
     CDS             complement(1747..2505)
                     /locus_tag="VXC24_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate dehydrogenase"
                     /protein_id="HEV0494158.1"
                     /translation="MILKDPSLKELLIQKAGNTNFVISDFIREEEVPKLINLIGVKEL
                     KFWYLINLENCQNHSYNLFQKLGEKDVDFSVEVLKKIDELRIGHSNLGYMVLHSISEF
                     RDKKEIYKKFIRFAINRPYYYYNNMIDDIIKNDSQIILEILEETNNEQSAIRLVNLGV
                     EFLENNNQKLILFNLLRAKGFGKKSFQEIHFTPYSHFYTDSHVPVLELEKELLERIKK
                     IFETGIDYINLLLYLNKLIDCKRKAIERELEKEF"
BASE COUNT          811 a          465 c          419 g          839 t
ORIGIN      
        1 aaaaactgaa ttgaaagaat ttttagaaaa tttctgtttt ttctttacag tgaaaaaaaa
       61 ttctgctata atgtcttatg taataaaata tgacaataaa aggagaacga tatgacatct
      121 gctaaagaat atatccaaag cgtgtttgaa actgtaaaag ctcgtaacgg gcacgaggct
      181 gaattcctcc aagctgttga agaatttttc aacactttgg aacctgtatt tgaaaaacac
      241 cctgagtata tcgaagaaaa tatcttggca cgtattactg agcctgagcg cgtgatttct
      301 ttccgtgttc cttgggttga ccgtgatgga aaagttcaag taaaccgcgg ctaccgtgtt
      361 caattcaact cagctgttgg accatacaaa ggtggacttc gtttccaccc aactgtaaac
      421 caagggatct tgaaattcct cggatttgaa caaatcttta aaaatgtctt gactggactt
      481 cctatcggtg gaggtaaagg tggatcagac ttcgatccta aaggtaaaac agatgctgaa
      541 gtgatgcgct tctgccaaag cttcatgact gaattgcaaa aacacatcgg accatcactt
      601 gacgtacctg ctggtgatat cggtgttggt ggacgtgaaa ttggttacct ttacggtcaa
      661 tacaaacgtc ttaaccaatt tgatgctggt gtcttgactg gtaaacctct tggatttggt
      721 ggtagcttga ttcgtccaga agcaactggt tacggtttgg tttactatac tgaagaaatg
      781 ctcaaagcta acggtaacag ctttgctggt aagaaagtcg ttatttcagg ttctggtaac
      841 gttgctcaat acgctcttca aaaagcaacc gaacttggtg caacagttat ctctgtttct
      901 gactcaaacg gctatgttat cgatgaaaac ggtatcgact tcgatctttt ggttgatgtt
      961 aaagaaaaac gtcgcgctcg tttgactgag tatgcagctg agaaagcaac tgctacttat
     1021 catgaaggtt ctgtatggac ttacgctgga aactatgaca ttgcgcttcc atgtgctact
     1081 caaaacgaaa tcaacggtga agcagctaaa cgtttggttg ctcaaggcgt tatctgtgta
     1141 tctgaaggtg ccaacatgcc aagcaacctt gatgccatca aagtttacaa agaaaatggt
     1201 atcttctacg gacctgccaa agctgccaac gctggtggtg tagccgtttc agcccttgaa
     1261 atgagccaaa acagccttcg cctctcatgg actcgtgaag aagttgatgg acgtctcaaa
     1321 gacatcatga ccaacatctt taacacagct aaaacaactt cagaaacata tggtcttgat
     1381 aaagactacc ttgcaggagc taacattgct gcctttgaaa atgtagcaaa cgctatgatt
     1441 gcacaaggcg tggtataaaa aaaaattacg gaaactgact acccagacgg gtagccagtt
     1501 ttttcaattc ctaaaattta agattctaat accctttatg caaaaatata gaattctacc
     1561 tttttcttta tataggctaa tgtttttaat atatttattg tctatttttg aaaagacaat
     1621 aaaactattc tactatagat tatcatttcc cacaattcat aactcaaacc taatattttg
     1681 ttataaaaca gtagatttta tttattatat ctggcacctt aaaaagtaag aaatataaat
     1741 taaaatttaa aactcttttt ccaattctct ttcaatagct tttcgcttgc aatcaattag
     1801 tttattcaag tacagtagca agttaatgta gtctataccc gtttcaaata tctttttaat
     1861 tctttctagg agttcttttt ctaattccaa caccggaaca tgactatcag tataaaaatg
     1921 tgaataggga gtaaaatgta tttcttggaa tgacttctta ccaaatcctt tagctctgag
     1981 aagattaaat agtattagtt tttgattgtt gttttctaaa aattctacac ctagattgac
     2041 caatctaatt gcagattgct cattatttgt ttcctccagt atttctaata tgatctgact
     2101 gtcatttttt ataatatcat caatcatatt attgtagtag taatatggcc tatttattgc
     2161 aaaacggata aactttttat aaatttcttt cttatctcta aattcactta tagaatgtaa
     2221 taccatgtat cctaaattgg aatgacctat tctcaattca tcaattttct tcaatacttc
     2281 taccgaaaaa tcaacatctt tttcacctaa tttttgaaaa agattatagc tgtgattctg
     2341 acaattttct aaatttatta aataccaaaa cttcaactct tttactccaa ttagatttat
     2401 taattttggc acctcttctt ctcttataaa atcagaaata acaaaatttg tattcccagc
     2461 tttttgtatt aacaactctt ttaaactagg atctttcaaa atcaatctct caaaatttaa
     2521 aattgtaaaa taac
//
LOCUS       DAVLBN010000114         2480 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLBN010000114 DAVLBN010000000
VERSION     DAVLBN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.114"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..335)
                     /locus_tag="VXC24_002117"
     CDS             complement(<1..335)
                     /locus_tag="VXC24_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494159.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGD"
     gene            complement(349..1062)
                     /locus_tag="VXC24_002118"
     CDS             complement(349..1062)
                     /locus_tag="VXC24_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0494160.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1522..1902)
                     /locus_tag="VXC24_002119"
     CDS             complement(1522..1902)
                     /locus_tag="VXC24_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0494161.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2319..2471)
                     /locus_tag="VXC24_002120"
     CDS             complement(2319..2471)
                     /locus_tag="VXC24_002120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494162.1"
                     /translation="MLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLA
                     LLKESK"
BASE COUNT          804 a          491 c          378 g          807 t
ORIGIN      
        1 aaatctccca tacagccatt acgattcata ttgaggctat attttcgatt agtaagataa
       61 ttcggaaata tatttcctat tactctaaga ttatctactt gtgaatccct tctcccaata
      121 taatcccctt ctttgactaa tgatggagat ttccaagtaa aaattaaatc gccagagaaa
      181 tttttcttat caaaaaactt aaaaagagat tgataaatac tatttgctaa ttgacaagtg
      241 tcagatgtaa attcataatt aacagcttca ttaaaatcaa cttcagacat ttcaatgtac
      301 tcttcaatag taatattagc tttttttgta gtcattagct aatctccttt aaaatgtgat
      361 cttttcaaga atatttttat ctaaacaatc cagcaagtct tggtaagaat agacttcgta
      421 agtcggctgg gcttgtgtgt gattttcgag gtgatgagga ttataccaga tagtgtcaat
      481 ccccgcatta ttgccacctt gaatgtcggc ggttagagaa tctccaatca tcagcgtctt
      541 ttctttacta aatccagcaa tttgctggcc aatcttttca taaaagagag catccggctt
      601 ttgagtttgc aactgttctg agataaagac ttgattgaaa taaggtgcta gaccagattg
      661 agccaaacgt cctgtctgaa tggcagtaat gccatttgtc gcagcataca agtcataatc
      721 acgctcaatg aggctgtcca agagatcatg agcgcccgat agtgtttgtc cctgctgggc
      781 gaggtaaaat tggtaacgct gggcaagaaa actaccgtct ttttcctgtc caaaatgaga
      841 aaataaacga gaaaagcgcg tgttaaccag ctcttgttta ctgattttct tcagctccaa
      901 gtctttccag agagccttgt tcataggaac gtaataatct ttataagcct gaatatccgc
      961 aactccttct tcttttagaa gttgggtcaa agccacatcc tcagcagcat caaaatcaag
     1021 aagagtgtgg tcgaggtcga agagtagaaa tttgtagaac aatttgaggt tttcctttct
     1081 gaaaattcat taaaaacatt atatcataaa gcacctcata caattaacta atttaatcac
     1141 ttaaaaaaaa ttcgaacact ttctatacaa ctgacagctc aaatctttca gaatagaaca
     1201 atactaacta tcgagcaccc ccgtcttcat aaatatatgt gtaattctag acctagaatt
     1261 cctataaact aaatgctttc atactcttcc aagtaattga ttgccttaaa ttttaatttt
     1321 tgaaggattc taaagctaga atagccccat cacaatcagt tttgattgat tcacaattta
     1381 gaaacactat agtttcactc ctgttaaaat aaaaaggaac tgcataaagc aatccctttc
     1441 taattttgaa atcatttact taacatttta tagttgagat aatcaatagc ttacctataa
     1501 aaagagttat agtaaaattc cttatttatt gatttcaagc tccgctaact gtgtttgaat
     1561 aactgacagt tctgcaccag cctgcagaag agcagctgca ttataggcac cttctacaat
     1621 tggaaccctg ttgatgatga tacttttatc actgaaatca gtcaccattt ttaagttcat
     1681 tttagcagaa cctaggtcaa aaaaggcaag taaagtatct gctggatttt cggaaacaac
     1741 cctatctact tgatcaaaac tcgttccaat tcctccgccc tcggttcctc ctacataagt
     1801 aatcggaaca tctttagcta ctttactaat cagttcaaca acaccttctg caatgtgttt
     1861 ggaatgtgaa acgataacaa gaccaatacc aatactttcc atcaaaccac cccagtttct
     1921 aaaatagcag taaagagtaa tcctgatgag aatgatccag gatcaatatg tccaagaaac
     1981 catatgctcc taagacaaga gccaacagac tggtcatcaa taatagtatt gttctttttt
     2041 tcatcattac tccttaacta gtgtttaact gattaattag ccagtaaata gtttatcttt
     2101 atttacacta tctgttaaga tatagtaaaa taagaacagg acagtcaaat cgatttctaa
     2161 caatgtttta gaagtagagg tatactattc tagtttcaat ctactatatt ttgcacattt
     2221 tcatgaaaaa aatgagaact agaactcaca ttctgctctc atttttcgtt ttcccgttct
     2281 cctatcctgt ttttaggagt tagaaaatgc tgctaccttt acttactctc ctttaataaa
     2341 gccaagagac tatctacttc tgctgaaata gtgttattat ctttcgttcc gagaagaaga
     2401 ctacttttta gaccagtcaa tgtctccaca gcattttgtc taatactaga atctgttact
     2461 ttttctagca aggcctccgc
//
LOCUS       DAVLBN010000115         2376 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLBN010000115 DAVLBN010000000
VERSION     DAVLBN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.115"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>2376)
                     /locus_tag="VXC24_002121"
     CDS             complement(<1..>2376)
                     /locus_tag="VXC24_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0494163.1"
                     /translation="ATKDKADKTLVVAEAGKLREEFSKMKVGGRNLWIKSKTVGAVIE
                     KLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNV
                     FNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLR
                     FNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSA
                     IQEYVNKDGQRQEALQRYTREESTRQATAVRELVNRDFVGKATYQEDVKGINQRIEAV
                     KTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQ
                     ISNLSNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANV
                     TNQLVRKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKVAKG
                     GRNYIRNGQFKNGSKNWLEYQSVNFGLNFNYQHSQNPNNRNRPGLHFYHDSQDVANFF
                     GIQQSFAFDGVRGEKVSVSLLVSKDGGDSNSGLKVALHYIKNKNIIGQEWQNIPSPQI
                     TSKYKRFTFTFTLSDDVENLNLMLFGEKGKTINLYVTDVQLERGSVATDYKEAPEDTD
                     EAIRSVQSQLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIK
                     SAMVDKLKTANFEAGSVTTTILDAEAVTAEKLKVDNALIRKLTANDAFIDQLISKRIF
                     STKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAG"
BASE COUNT          632 a          552 c          438 g          754 t
ORIGIN      
        1 cccggcacca ttccccatac caacagagaa ctgattgaca cctgaaatcc agcgaccgcc
       61 accctggtca aattgaccaa gtgtgaatcc accgattcgg ccttgatagg cttctaggaa
      121 ggttgagcta gaaatgacgg actcaacctt agtagagaag atacgtttag atatcagttg
      181 gtcaataaaa gcatcatttg cagttaattt tctaataagc gcattgtcaa ctttcaactt
      241 ctcagcagtt accgcttcag cgtctaatat cgtagtcgtg accgaaccag cttcaaaatt
      301 ggccgttttg agcttatcaa ccatggcaga cttgatgact gctctgtcaa tcagggtctc
      361 tccagtgatg tgggtcaatt tcccaacaaa gcggttatgt ccattggcgc caagattgat
      421 tccagagatg atatctccag ccgagttgat gttttgaact gcccatgagc cagttagttg
      481 gctttgaaca gagcgaatcg cttcgtccgt gtcttcagga gcttctttgt aatccgtcgc
      541 gacagaacct ctttcgagtt gaacatctgt aacatagagg ttgatggtct tccctttttc
      601 accaaacaac atcaaattca gattctctac atcgtctgat aaagtaaacg taaatgtgaa
      661 acgcttatac ttcgatgtta tttgtggact tgggatattt tgccactctt gcccaataat
      721 gtttttgttt ttgatgtagt gcaaagcgac tttcaagcca ctgttgctat cgccaccatc
      781 tttcgaaaca agaagagata cactcacttt ctcacctcga acaccatcaa atgcaaaaga
      841 ttgctgaatt ccaaaaaaat tagcaacatc ttgagaatcg tgatagaagt gtagtcctgg
      901 acgatttcga ttattaggat tttgagagtg ttgatagttg aaattcaaac caaaattaac
      961 agattgatat tcaagccagt ttttcgaacc gttcttaaat tgaccatttc tgatataatt
     1021 tcgaccacct ttggcaacct tcccaacctc aacctgaaac agttgattgg tcagagccat
     1081 gcgagcaacc ttatccgcaa ttccattttc agtattgccc aaaatccgct cgtaaagttt
     1141 actggtttcc ttaacacgct ggaagtcagt agtctctact tttcgcacta gttgattggt
     1201 cacattcgca aattgactat cagcattcgc tttgtttgca gaaacctgat cagatattct
     1261 acccatttgt cgttcagcat tatccttgtt tgtagcgacc tgagtcttta aatttgaaat
     1321 ctgattatct gtgccttgct tattactgtt tatccgattt gaaagatttg aaatctgagt
     1381 agtggttcct tgctcactgc ttgtaagtct atttgataga ccactgattt gaccgcccac
     1441 atcttgctta taagtagtta tctgacttga aatatccgtg aacttaccat ctacagattg
     1501 acgatagcta gcgatttgac tagcgatgtc tttattcgca ctagttttaa cagcttcaat
     1561 cctctgattg atacccttaa catcttcttg ataagtagcc ttaccaacga aatcacgatt
     1621 gaccagctca cggactgctg tcgcttgtct cgtgctctcc tcacgagtat agcgctgtag
     1681 ggcttcctgt cgctgaccgt ctttatttac atattcctga atagctgata agtcggttcg
     1741 caagccctga gctgtccgct caaaggtagc cttagcctca gtgatgagac catcagcgtc
     1801 ctcaggcgca ggactccagt ccgtcgccac actaccgatt tcaaccttga ttcctgttac
     1861 ccaagctgta ccgcttgtag caccttcaag attgaatcgc aatgatgtct tcaattgatc
     1921 aaaatttgtt ttttcagagt agtcataagt gaatgtaata tatttccaat ctgccgaacc
     1981 tttatacata ccaagcgtag cataatctgg accactctgt actccggtct cactattttt
     2041 tctaaaaaga taatgtttga agcaattaaa tacattccaa aaatttcgac cttggactac
     2101 attttcgtac ttgatccaag cgctaaaagt aactttttgg tacaaccttg agctgaaatc
     2161 tggttcaagg ttgaacgtta aagtagagtt gttctctagc ctatagcatt ctttttgacc
     2221 tgtgacgtgg ttttcaggta atttttcaat tacagctcca accgtcttgg attttatcca
     2281 tagattccgg cctcccacct tcatttttga aaattcttca cgcaatttcc cagcttcagc
     2341 cacgacaaga gtcttatctg ccttatcctt ggttgc
//
LOCUS       DAVLBN010000116         2340 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLBN010000116 DAVLBN010000000
VERSION     DAVLBN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.116"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..394
                     /locus_tag="VXC24_002122"
     CDS             <1..394
                     /locus_tag="VXC24_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HEV0494164.1"
                     /translation="VYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDL
                     VTATVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAI
                     DSTCSMLQPQSLVKELIKLENIVLEEGH"
     gene            615..1721
                     /locus_tag="VXC24_002123"
     CDS             615..1721
                     /locus_tag="VXC24_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEV0494165.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            1697..>2340
                     /locus_tag="VXC24_002124"
     CDS             1697..>2340
                     /locus_tag="VXC24_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494166.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLT"
BASE COUNT          853 a          284 c          403 g          800 t
ORIGIN      
        1 agtttatgat gaaatatttg ttgaagaggt agttccgcac gtttttctgc catatgaatc
       61 tgacttactt cttattttac cagctacggc aaatgtgatt ggcaaaattg ctaatggtat
      121 tgctgatgat ttagttacag caactgtttt aaactttaat aaaaaaataa ttttttgtcc
      181 caatatgaac tctactatgt gggacaatca catagttcaa agaaatgtat caattctaaa
      241 ggagttggga catatatttt tatttgagtc taaaaaaaca tatgaggtag gattgcgtaa
      301 agcaatagat tcaacatgtt caatgttaca accacagtcg ttagtaaaag aacttatcaa
      361 attagaaaat attgtccttg aagagggaca ttaaaaacta ctgagaatat taaggagggg
      421 aaaaaatgga aaattcatca atcgatgtag atatgctgtt ggaagaattg acacaagaag
      481 caatggtcgt tgttgctgtt gataaggact gttaatttaa acttatggca atatatgaaa
      541 ggttactgga tgttttaaat tatgcaggca gtagcctttt attatataca aatggataaa
      601 gtaaggataa tacaatgatt aataaaaaaa tacaacaagt tgttttggaa tcattacaga
      661 attttttgaa tgggaacttc atttcgcctt gtgtagtcta tgattttggc ttgctggaaa
      721 ctgtacttga tgaatttaaa aatcaaattc ctgtaacatt caattaccaa cttttttatg
      781 ccgttaaagc aaattcaaat gagaagatac ttgaattctt agtagataaa attgatggag
      841 ttgatgtggc gtcattatct gaattagatg tggctaaaaa atttttccca ccaactcaaa
      901 tttctgttaa tggtcccgca ttttcttatg aaactttata taatctgatt aaaaaacaat
      961 ataaagttga tattaacttt ttggaacatc ttcaacaatt ttccccaaaa gaatctgttg
     1021 gaataagagt aacggagcca gatgaactta ataatcgtat gagtcgattt ggaataaata
     1081 tttgcagtga taattggact agtaatttac aaaatccttt aattacacga ctgcattttc
     1141 attttggaga aaaagatgat aaatttattg ttaagttaga taaaatatta tttaagttac
     1201 aagaaattaa taaacttaga gaggttagag aaataaatct tggaggcggt tttatgaaat
     1261 tatttatgga aaatcgtttg aaagaatttt ttctatcact tatggaaatc tataaaaagt
     1321 acgatattga tagtactgtg actacaataa tagaaccagg tagtgcaatt acttcatttt
     1381 ctgcctatat gattactagc ccagttaatg ttagtgaggt gaatgagcag caggttatca
     1441 cgttagacac atcaatatac accaatacat tatggtttgt tccgcatatt attacaacgt
     1501 taaattcaag tagtaaagag cgttatagta ctattctcta tggtaatacc tgttatgaac
     1561 atgacaagta taaaatgaaa gtttcgcttc caaggttaac tcaaaatagc agtatagtgt
     1621 tttttcctgt aggagcttat ataaaaagca atcattcaaa tttacatcgt aatgatttta
     1681 tgcgggaggt atatttgtgg acaaaaaact tgacatatta gataaagtta aggaatattt
     1741 aggaaataaa actactcaaa ttctggataa tcaatataaa gaatttttga aacttaatga
     1801 tataaggcga gcgtttggta tttcagaaaa agtattaaac aattctttta attttacgag
     1861 taaagaattt aatgatttaa ttaataacga aaattattta ttcgaatatg catgtagaat
     1921 tagagaggaa tggagaaaaa aatgctttaa tcattcttat cgttttctat gctcacctat
     1981 aattacagat gattttctta acacgaagac attgagaagt agccaaattg aatataaata
     2041 tgagcgatat ttatcgaaaa gttcgatagg cgatagagcg gttgatggct ttgtttcctt
     2101 caatacttta acagctaatg gtatgtctgc tattaaacta tgtcttgaga tattaaactc
     2161 tattttcttc aagaagaaga ttgatttatt atattcaacc ggatattatg aaacaagatt
     2221 tttattaaat aatcttgcta aatcaggtat tagttgctat gaggtaagta attgtgaatt
     2281 ggataaagat aaattttata atgtattcat gatggaaccc aatcgagccg atttaacatt
//
LOCUS       DAVLBN010000117         2310 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLBN010000117 DAVLBN010000000
VERSION     DAVLBN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.117"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            43..915
                     /locus_tag="VXC24_002125"
     CDS             43..915
                     /locus_tag="VXC24_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0494167.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            915..1709
                     /locus_tag="VXC24_002126"
     CDS             915..1709
                     /locus_tag="VXC24_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0494168.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT          859 a          342 c          380 g          729 t
ORIGIN      
        1 ttcgttttac ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat
       61 agtgaaactg ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta
      121 gcaggaatta tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta
      181 agaaatcctc ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg
      241 gtcttttgca tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact
      301 tgtggactaa catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca
      361 gcaagactga taatattagg cattggtttt caagctgtca caagagcagg cacctcattt
      421 ttattgttga aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct
      481 ttatctttta caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact
      541 atattagttt tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca
      601 atcggacttg gagcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct
      661 ttaactgctt tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt
      721 cccatagcct taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt
      781 ttactagttt tgttatcaga catattctct caaaatattt taccagctag atatccagta
      841 ggtgttgtaa ctggcttgtt aggttcacca tacttaatat atttactaat aaaaatgaac
      901 aggaggaata tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa
      961 aaataatctt ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg
     1021 ggtcaaatgg ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat
     1081 tagagggaga agtattgctt gataataaat caattaattc ttataaagaa aaagatttag
     1141 caaaacacat agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg
     1201 atcttgtaag ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg
     1261 accttgaaat aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc
     1321 tagttgaaga actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc
     1381 aagatacaag tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa
     1441 tagaactatt agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga
     1501 ttttgcacga tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag
     1561 gtaaacttgt tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata
     1621 tctttaatct tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc
     1681 ctattggcaa gcaccatgtt agctcttaat aattgaatat tggaattcat ttaaaagtcg
     1741 caaattttga actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt
     1801 ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa
     1861 aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa
     1921 gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc
     1981 tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag
     2041 aaatatttat taccgaaaaa aaggggaaat cgagtcaagt accaacaggc tcatctattc
     2101 caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg
     2161 gtatcttagg ttactacgaa gatatagatg ataaaaatta tagagttttt gaaaatttta
     2221 tatctgtttc atttttagga gcagtctttt atcataaata taaagcaagc ctagatatga
     2281 aaattcattg tttaaaatta aaaaataaag
//
LOCUS       DAVLBN010000118         2270 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLBN010000118 DAVLBN010000000
VERSION     DAVLBN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.118"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            81..263
                     /locus_tag="VXC24_002127"
     CDS             81..263
                     /locus_tag="VXC24_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0494169.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            273..638
                     /locus_tag="VXC24_002128"
     CDS             273..638
                     /locus_tag="VXC24_002128"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0494170.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            635..1813
                     /locus_tag="VXC24_002129"
     CDS             635..1813
                     /locus_tag="VXC24_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0494171.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            1982..2270
                     /locus_tag="VXC24_002130"
                     /pseudo
     CDS             1982..2270
                     /locus_tag="VXC24_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          882 a          316 c          394 g          678 t
ORIGIN      
        1 attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag
       61 ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag
      121 ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt
      181 ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa
      241 aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaagt acaaaaccta
      301 agacttttga aattgattgt ttagtcggag aaaaacacgc atacgaaata aaatggtggg
      361 atgcaactac agatggagac catataacta aagaacacac tagaataaaa gttattcata
      421 acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa
      481 aaattcagca aactttagaa acattgtata acggtattgg agggaaatat tattatggag
      541 attctgcctg ggaacattta agagcagtga ccggtattga tttacttagt attctaacag
      601 atattgcaaa taaaaaaaca ggggtaaaat caaaatgaca gtattaaaag gagataactt
      661 agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg accctccttt
      721 ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt cattcgaaga
      781 tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag aagaatgcaa
      841 aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg caaatcatca
      901 tattagatta attttagata atatctttgg agcagatatg tttcaaagcg aaattatatg
      961 gaactataaa cgatggtcta attcaaaaaa gggattattg aacaatcatc aaaacattta
     1021 cttttattca aagtcaaaag attttaaatt taatacaatt tttacagagt attcttctac
     1081 tacaaatatc gaccaaatac tagtggaacg aaaacgagat ggaaactcta aaactatata
     1141 taaagttgat aataatggta actatattct agcaaaagag aaaaatggag ttcccctttc
     1201 agatgtttgg aatataccat ttcttaatcc aaaagctaaa gaaagagtag gttatcctac
     1261 acaaaaacct attctgttat tagaacaaat tataaagatt gctactgata aaaatgatat
     1321 agttttagac ccgttctgtg gaagcggaac tactttagta gcctccaaga ttttgaatag
     1381 aaattatatg gggattgatt tatctgagga agctatcaat ataactcagc aacgtctgga
     1441 aaatgttata aaaacaagtt caaatttatt gaataaagga atcgaagcat atagaaccaa
     1501 aactgaggaa gaggaaaaca ttcttaaatt attacaggca aaaattgttc aaagaaataa
     1561 aggaattgat ggttttttac ctaaacattt tcaaaaaaaa ccgataccta taaaaattca
     1621 aaaaaataat gaatgtctga atgagagtat ctctttatta cagaatgcta taaactccaa
     1681 aaaacttgat tttggagtag ttataaaaac tcattcagat aatttattat ttgattttga
     1741 tacgattcct gaaaatataa tagtagttga ccattttgaa cttacaatcg aaaaatggtt
     1801 aagtaaaagt taacagttac tatagtttgc aaattattta cagaaagaac aagaattcct
     1861 aggagattat tctggctatg ttcattgtga catgttgcgg cagtaactta ggactttagt
     1921 cctctagttc tgcctatgcg atagcagtcc aaagtttagg agtaaggcga cgctaagctt
     1981 ggtaaactgc gaacagctag aagcttatcg tcaactggaa gaagctgcac ttgttggatg
     2041 ttgggcgcat gtgagaagga agttttttga agcgaccccc aagcaagcag ataaatcatc
     2101 cttaggagct aaaggtttag cttattgtga tcagttattt tccttggaaa gagactggga
     2161 ggctttgcca gctgatgaac gactacagaa acgtcaagaa catctccaac ccctaatgga
     2221 agacttcttt gcttggtgcc gccgtcagtc agttttagca ggttcaaaac
//
LOCUS       DAVLBN010000119         2101 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLBN010000119 DAVLBN010000000
VERSION     DAVLBN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.119"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            40..491
                     /locus_tag="VXC24_002131"
                     /pseudo
     CDS             40..491
                     /locus_tag="VXC24_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="VXC24_002132"
     CDS             656..955
                     /locus_tag="VXC24_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0494172.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1064..>2101)
                     /locus_tag="VXC24_002133"
     CDS             complement(1064..>2101)
                     /locus_tag="VXC24_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0494173.1"
                     /translation="RVSLEYGLPSRTILLNWLAQYRKNGYTIVEKTKGRVPESGECHP
                     KKVKRTPIEGGKRERRKTEIVQELMTEFSLVLLLKSIKLARSTYYYHLKQLDKTDKDQ
                     ELKAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYS
                     SHKGDVGKKAENLIQGQFEGSKTMGKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIA
                     YNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSR
                     KGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGL
                     SLVQYRTKSFG"
BASE COUNT          653 a          408 c          364 g          676 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagt gaatacagac tatattactc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gaaaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 tagcaagagt tttgtactga ccccaaaaag ttagacaaat aatttatccg aaggatttag
     1081 ttctgtattg cacaaggcta agtcctttta gttttacctt aattcgttta ttgttgtagt
     1141 aatcaatata gtctacaata gcttgttcca attgattaag tgatttaaat gttttctcat
     1201 agccataaaa catttccgat ttcagaatcc caaagaagga ctccatcata ccgttgtctt
     1261 ggctgtttcc cttacgtgac atggatgctt gaattccctt accctcaaga aactgatgat
     1321 aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
     1381 tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt gaagttgaaa
     1441 gattataggc gataatttcg ctattaaagc catctaaaac tggtgataag taaagctttt
     1501 gagtacttgc tggaatggca aattctgtca catctgtata gcactttccc attgttttag
     1561 agccttcaaa ttggccttga atgagattct ctgccttctt gccaacgtct cctttatgag
     1621 aagaatattt tcgtttctgt cgcattttag cttgtaaatt gagtactttc atcaagcctt
     1681 gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa atccgacgat
     1741 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
     1801 ccttatctgt tttgtctagc tgtttcaagt gatagtagta ggtcgaacga gctagtttaa
     1861 tggattttag aagaagaact aacgaaaact cagtcattaa ttcttgaaca atttctgtct
     1921 ttcttctttc tctttttcct ccttcaatcg gagttctctt aactttttta ggatggcatt
     1981 ctccgctctc aggtactctc ccttttgttt tctcaacaat agtatacccg tttttcctgt
     2041 attgtgctag ccagttaaga agtatcgtac gacttgggag gccgtattca agagaaactc
     2101 t
//
LOCUS       DAVLBN010000120         2044 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLBN010000120 DAVLBN010000000
VERSION     DAVLBN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.120"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            2..1027
                     /locus_tag="VXC24_002134"
     CDS             2..1027
                     /locus_tag="VXC24_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0494174.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1017..2024
                     /locus_tag="VXC24_002135"
     CDS             1017..2024
                     /locus_tag="VXC24_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0494175.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          719 a          290 c          365 g          670 t
ORIGIN      
        1 tatgaaaaac aaattttttc taatagctat tttagctatg tgtatagttt ttagcgcttg
       61 ttcttctaat tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc ctgataaaat
      121 agttttagat catgctttcg gtcaaactat attagataaa aaacctgaaa gagttgcaac
      181 tattgcttgg ggaaatcatg atgtagcatt agctttagga atagttcctg ttggattttc
      241 aaaagcaaat tacggtgtaa gtgctgataa aggagtttta ccatggacag aagaaaaaat
      301 caaagaacta aatggtaaag ctaacctatt tgacgatttg gatggactta actttgaagc
      361 aatatcaaat tctaaaccag atgttatctt agcaggttat tctggtataa ctaaagaaga
      421 ttatgacact ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac cttggcaaac
      481 tttatggaga gatatgatta aaattgattc aaaagcctta ggtatggaaa aagaaggtga
      541 tgagttaatc aaaaatactg aagctcgtat atccaaagaa ttagaaaaac atccagaaat
      601 caaaggaaaa atcaaaggaa aaaaagtatt atttactatg attaatgctg cagatacatc
      661 aaaattctgg atttatacta gcaaagatcc aagagcaaat tatttaacag atttaggtct
      721 agttttccct gaatcattaa aagaatttga gagtgaagat agttttgcaa aggaaatttc
      781 tgcagaagaa gcaaataaga taaatgatgc tgatgtaatc ataacttatg gtgatgataa
      841 aactcttgaa gctttacaaa aagatcctct tttaggtaaa ataaatgcaa ttaaaaatgg
      901 tgccgttgct gtaattccag ataatacacc gttagcagcc tcatgcactc caacaccact
      961 ttcaataaac tatactattg aagaatacct aaatctttta ggaaatgcat gcaaaaatgc
     1021 gaaataaaaa acaaataaac ctaggcataa tttttgtaat ctgcctaggt cttcttatta
     1081 caatattttt gtcattaaag cttggaacaa aagaaattaa tatcagagat tttttagcag
     1141 cttttggaat gggtaataca aatgatgatt ttattaaatc aattatatat aaaagaatac
     1201 ctagaactat ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt gtattgatgc
     1261 aatcagttac tagaaaccca atagctgatc caggtatact cggtataaac acaggagcaa
     1321 gtcttagtgt agtaattggt ctttcttttt taggaatttc atcaagcata agccatataa
     1381 gttttgcaat cattggtggc ttagtaagtg caatttttgt atacgcgatt gctgtaagcg
     1441 gaaaagcagg ccttacccct ataaaacttg ccttatcagg aacttgtgtt agtatggctt
     1501 taagcagttt tgtaagtttt ttaattttac cgaataataa cgtcttagac aaatttagat
     1561 tttggcaaat aggtagcctt ggagcagcta cattatcttc tatatctaca ctactacctt
     1621 ttataatttt aggtcacttg atagctatat ttatttcatc agatttaaac gctttagcta
     1681 tgggtgatga aatggctgtt ggtcttggag ttaatgttaa taggataaga tcacttgcaa
     1741 taattgcaag tgtgctttta tgttcaagta ttactgcaat tggtggacct attggcttcg
     1801 taggtcttat agttcctcac ttttgtggct tatttataag caaagatata cgcacaatga
     1861 ccatttcttc atcttttata ggtgcagagc tcttgcttat atgtgatata atcggccgta
     1921 tgttaggtaa accaggtgaa attgaagtag ggataattac tgcaataatc gggggtccag
     1981 tacttattta tgtaactatg aaaaatagag gggttaataa ctaatgcaaa atttaattat
     2041 aggt
//
LOCUS       DAVLBN010000121         2004 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLBN010000121 DAVLBN010000000
VERSION     DAVLBN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.121"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            132..1256
                     /locus_tag="VXC24_002136"
     CDS             132..1256
                     /locus_tag="VXC24_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0494176.1"
                     /translation="MGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNFLSVTFSSIT
                     GDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKKVFFALLLLH
                     IVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQK
                     HLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEVLVKANHKLR
                     SDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIMS
                     VLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGRN
                     RGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            1253..>2004
                     /locus_tag="VXC24_002137"
     CDS             1253..>2004
                     /locus_tag="VXC24_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0494177.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
BASE COUNT          685 a          283 c          365 g          671 t
ORIGIN      
        1 gtaaagatca aataaataga aaagaattat tcttttttgg tgcttataca ttactaacag
       61 aaatagtact tgattttccc ttctatcttc tatatttaga tgggttaggg attgcaacat
      121 ttttatttcc tttgggccta tattcctatt ttcgatggat gaaacagtat gagagggata
      181 gaggactatt tctaagttta ctactatctc ttttatatga gagcactcat aactttctgt
      241 ccgtaacttt ctcttctata acaggagaca attttgtttt acagtattat ggcctattct
      301 ttttcgttgt gacggtgttg acctattttg ttacattaaa aatcatttat tatttccatt
      361 tggaactagc ctattttgac aaggactacc tttatccttt cttgaaaaaa gtattttttg
      421 ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt
      481 tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct
      541 ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgctttgaag cagaagaaat
      601 ttgaacagaa acatttacag aattacacag atgaaattgt cggtctgtat aatgaaatcc
      661 gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg
      721 gtaatttaca ggaaattgac agagtttaca atgaagtttt ggtcaaagca aatcataaac
      781 tacgttcaga taagtacact tactttgatt tgaacaacat agaagattca gctttacgaa
      841 gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag
      901 taaaagatac gattaccaag cttccaattg aactattgga tttagtgcgt atcatgagcg
      961 ttttattgaa caatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag
     1021 cagttattaa gatggaaact gaaacagtta ttgtgattca gaattcatgt aaaatgacga
     1081 tgactccttc aggagatcta tttgccttag gattctccac taagggaaga aatcgcggag
     1141 tcggattaaa taatgtgaaa gaactactag ataagtacaa caacattatt ttagaaacag
     1201 agatggaagg cagtacattt agacaaatca ttagatttaa gaggaaattt gaatgaaagt
     1261 tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat
     1321 ttcgaaagaa tcgaatactc caatatcata caagacaacg ggaaaagtcc gtgaatttga
     1381 agaatacatt gaaaatgatg aagtaaatca actttatttc ctagatatcg atattcatgg
     1441 aattgagaaa aagggatttg aagttgctca actcattcgt cattacaatc cttacgctat
     1501 tatcgtcttt atcaccagtc gatcagagtt tgcgactctg acctataaat accagatatc
     1561 agccctagat tttgttgata aggatatcaa cgatgagatg tttaagaagc gaattgagca
     1621 aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga
     1681 ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac
     1741 gacaggagtc tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg
     1801 taccatgaca gatattcagg aaaaggacaa acatgctcag cgattttatt ctcctcacaa
     1861 gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt
     1921 tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat
     1981 tttagagaaa aaatctcaaa agtg
//
LOCUS       DAVLBN010000122         1887 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLBN010000122 DAVLBN010000000
VERSION     DAVLBN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.122"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(165..1796)
                     /locus_tag="VXC24_002138"
     CDS             complement(165..1796)
                     /locus_tag="VXC24_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0494178.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT          576 a          371 c          396 g          544 t
ORIGIN      
        1 taacaggaca aatcgatttc taacaatgtt ttagaaatag aggtgtacta ttctagtttc
       61 aatatactat atatctgcag aatactcttt cagtttcatt cagcctagtc ttgcttagga
      121 aaaagtaaga agccatccaa ttatgatgga tagcttcttg gttattagat ttgttctgca
      181 aaaacctttt cagcaaggtt catagcgtgg tctgatacac gagtgtagtg tgagatgatg
      241 tcgataaagt tgaccccagc ttgtgttgaa cattcgcctt tgttgaggcg tttgatgtgg
      301 gtttttctga gaacacgttc tatcttattg attgcttcat gacgttctac aagactgcgt
      361 gctttttcaa tatcattgtt ttccacacta tccagagcat ctttgataaa gtcactagtt
      421 tggcggtaaa cttcctctaa ttctttcaag gcggcatcag aaaattcaac atttttccgt
      481 tgaagatagt cagtcagatt gagtagagcc tccgtgtggt ctccaatccg ttccaaatca
      541 cgggaggaat caaggatatt ggtaagcact tcactttctt tttggctgag agcttcgctt
      601 gaaagggcaa tgagataacg tgttaattgc tcatcgatgg tgttaattgc ttcttcggtt
      661 ttatgccctt tttcagcaac tttttcatcc aagtcaatga tgtacttata ggaaaggtca
      721 aaggctttag cagcgtagtt tcctaagtgc aagagctctt tcttagcatt tcctagagcg
      781 atagatgggg cctgtttgat gaaatgttca tcaagatata agggttcgta tttgacaacc
      841 tcgtcctctc caggaataat cttggttaca aagtaagcca gagctccgat aaatggaaat
      901 tggacaatgg tgttggtaat attaaaggtt ccgtgagcaa aggcgatggt catttccggt
      961 gctagattta gcgtagcttc aaaccaatga atcaggacag taaaaggaac tagaaaaata
     1021 acgcagacga ctgttccgat aatgttgaag gcaacatgag ctcctgctac ccgtttagct
     1081 gcaatattag cccctaaaga ggcaatgatg gctgtaatgg ttgtcccgat attgtcacca
     1141 aatagaactg gcaaagctcc ctgtaggtca attagattgc cggcgtagag gttttgtaaa
     1201 atcccaatgg tagccgaaga agcttgaatt agcaaggtca agccagtacc gacaaagaca
     1261 cccaaaacag gattcttact tagctcaatc atatagtcct taaagacctg taaatccttg
     1321 agtggagcca ttgcgccgct catgagattg agggcaaaaa agataccacc gataccaaag
     1381 aggatgcgtc cgatattatt gactgtccga tttttcgtaa aaaagagaca gacggcaccg
     1441 ataaagagca taggtagggc atagttacct aatttaaaac cgatgagaaa ggatgtgaca
     1501 gttgtcccaa tattagcacc catgacaatc ccgatagcct gacgtaaggt taagagaccg
     1561 gcactgacca ggccgactgt aataactgtt acaccagaac tagactgaat tagagcagtc
     1621 atcccaatac caaccagaac tccaaagaaa ggattactag tatatttgtc aatgtaaaaa
     1681 cgaaggcgat ctccagcagc ttgttgcaaa ccgtctccca tggtcttgat gctatataag
     1741 aatagcccca gaccacctaa aaagtgaaat aaaatttcct gccaattaat ggacatttct
     1801 ttttcctccg aaaaataatc gcggaatatc tcctattcta ttttaaagga taaaagtaaa
     1861 tctaacaagt gttaacgtca agtttgt
//
LOCUS       DAVLBN010000123         1855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLBN010000123 DAVLBN010000000
VERSION     DAVLBN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.123"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            16..88
                     /locus_tag="VXC24_002139"
     tRNA            16..88
                     /locus_tag="VXC24_002139"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49..51,aa:Asp,seq:gtc)
     gene            113..185
                     /locus_tag="VXC24_002140"
     tRNA            113..185
                     /locus_tag="VXC24_002140"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Lys,seq:ttt)
     gene            191..272
                     /locus_tag="VXC24_002141"
     tRNA            191..272
                     /locus_tag="VXC24_002141"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Leu,seq:tag)
     gene            291..363
                     /locus_tag="VXC24_002142"
     tRNA            291..363
                     /locus_tag="VXC24_002142"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:324..326,aa:Thr,seq:tgt)
     gene            386..457
                     /locus_tag="VXC24_002143"
     tRNA            386..457
                     /locus_tag="VXC24_002143"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Gly,seq:gcc)
     gene            465..550
                     /locus_tag="VXC24_002144"
     tRNA            465..550
                     /locus_tag="VXC24_002144"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:499..501,aa:Leu,seq:taa)
     gene            560..633
                     /locus_tag="VXC24_002145"
     tRNA            560..633
                     /locus_tag="VXC24_002145"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:594..596,aa:Arg,seq:acg)
     gene            649..722
                     /locus_tag="VXC24_002146"
     tRNA            649..722
                     /locus_tag="VXC24_002146"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:683..685,aa:Pro,seq:tgg)
     gene            728..801
                     /locus_tag="VXC24_002147"
     tRNA            728..801
                     /locus_tag="VXC24_002147"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:762..764,aa:Met,seq:cat)
     gene            815..888
                     /locus_tag="VXC24_002148"
     tRNA            815..888
                     /locus_tag="VXC24_002148"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:849..851,aa:Ile,seq:cat)
     gene            899..988
                     /locus_tag="VXC24_002149"
     tRNA            899..988
                     /locus_tag="VXC24_002149"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:935..937,aa:Ser,seq:tga)
     gene            999..1072
                     /locus_tag="VXC24_002150"
     tRNA            999..1072
                     /locus_tag="VXC24_002150"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1033..1035,aa:Met,seq:cat)
     gene            1076..1148
                     /locus_tag="VXC24_002151"
     tRNA            1076..1148
                     /locus_tag="VXC24_002151"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1109..1111,aa:Phe,seq:gaa)
     gene            1168..1238
                     /locus_tag="VXC24_002152"
     tRNA            1168..1238
                     /locus_tag="VXC24_002152"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1200..1202,aa:Gly,seq:tcc)
     gene            1274..1347
                     /locus_tag="VXC24_002153"
     tRNA            1274..1347
                     /locus_tag="VXC24_002153"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1308..1310,aa:Ile,seq:gat)
     gene            1354..1441
                     /locus_tag="VXC24_002154"
     tRNA            1354..1441
                     /locus_tag="VXC24_002154"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1388..1390,aa:Ser,seq:gct)
     gene            complement(1574..>1855)
                     /locus_tag="VXC24_002155"
     CDS             complement(1574..>1855)
                     /locus_tag="VXC24_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0494179.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          437 a          386 c          490 g          542 t
ORIGIN      
        1 ccgttaactc ccaaaggtcc cgtagtgtag cggttatcac gtcgccctgt cacggcgaag
       61 atcgcgggtt cgattcccgt cgggaccgtt taaggtaacg caagttattt tagactcgtt
      121 agctcagttg gtagagcaat tgacttttaa tcaatgggtc actggttcga gcccagtacg
      181 ggtcatatat gcgggtttgg cggaattggc agacgcacca gatttaggat ctggcgctta
      241 acggcgtggg ggttcaagtc ccttaacccg cattaagata taacaaatga gccggcttag
      301 ctcagttggt agagcatctg atttgtaatc agagggtcgc gtgttcaagt catgtagccg
      361 gcatttttag atagaagaaa acagtgcgaa cgtagttcag tggtagaaca ccaccttgcc
      421 aaggtggggg tcgcgggttc gaatcccgtc gttcgcttag agaggccggg gtggcggaac
      481 tggcagacgc acaggactta aaatcctgcg attggtaacg atcgtaccgg ttcgattccg
      541 gtcctcggca taatatggag cacccttagc tcaactggat agagtacctg actacgaatc
      601 aggcggttag aggttcgact cctctagggt gcatttttct atttaactcg ggaagtagct
      661 cagcttggta gagtacttgg tttgggacca aggtgtcgca ggttcgaatc ctgtcttccc
      721 gattcatggc ggtgtagctc agctggctag agcgtccggt tcatacccgg gaggtcgggg
      781 gttcgatccc cttcgccgct ataatgatct tgtcggacct ttagctcagc tggttagagc
      841 tctcggctca taaccgagtg gtcgtaggtt caagtcctac aaggtccatt tgaatattgg
      901 aggattaccc aagtccggct gaagggaacg gtcttgaaaa ccgtcaggcg tgtaaaagcg
      961 tgcgtgggtt cgaatcccac atcctccttt tatattaacg cgggatggag cagctcggta
     1021 gctcgtcggg ctcataaccc gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc
     1081 ggtagctcag ttggtagagc aatggattga agctccatgt gtcggcggtt cgattccgtc
     1141 tcgcgccatt ttattgatag tatttatgcg ggtgtagttt agtggtaaaa ctacagcctt
     1201 ccaagctgtt gtcgcgagtt cgattctcgt cacccgcttt gaactttgtt caaattacca
     1261 agttttttaa cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg
     1321 tcggtggttc gagtccactc gtgcccatta attggagaat tactcaagag gctgaagagg
     1381 acggtttgct aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc
     1441 gttttaatga gagtttgtaa ctctcttttt tatttttaga gacaataaag cttcagatcc
     1501 gtaaaactta attgaattac taatctgaag ttatttttag gctctttgtc aactgtagtg
     1561 ggttgaaaaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatgttca
     1621 aagcgataaa aatccttttt ttgaagtttt caaagttccg aaatccaaag gcgtttcgtt
     1681 tgataagttt gatgagatta tttgtcgctt ccagtttggc gttagaatag tgtagttgaa
     1741 gggcgttgac aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag
     1801 gatgaacctg cttcagattg tcctcaataa gcccgaaaaa tttctctggt tcctt
//
LOCUS       DAVLBN010000124         1810 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLBN010000124 DAVLBN010000000
VERSION     DAVLBN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.124"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            78..>1810
                     /locus_tag="VXC24_002156"
     CDS             78..>1810
                     /locus_tag="VXC24_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV0494180.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKER"
BASE COUNT          696 a          219 c          313 g          582 t
ORIGIN      
        1 agtttattga atgctatgta tttttatttc ttaatgctat aatataaagt atatagagtt
       61 attttagagg tgcagatttg gccaataata ggaaaactga gacattaggt gtttcatatc
      121 tttcaacatt tatagataag catgagttac ttcaatctta ttttgaaagt aatgataaaa
      181 ctccagtatg ggatggagaa attcatgttc ttaaatcacc gagtgagaag aaagacgaaa
      241 tattaggtaa agtacctgtt cagattaaaa ctactagaca gaaaaaagat gtgttaaaat
      301 ccttctcatt agatactaga gatttagaac tatataaacc aaatggtgga gtagttttat
      361 ttgtagtttg gttgaatgag gataatggtt taagagatat ttactataag tcattacctc
      421 ctctttctat aaagaatttg ctcaaaaaga gtaaactaaa aaataaatct acaaatagga
      481 agaaactttc catagagatt tttaaactgg atgagaaaaa aatgtatcca atgttagtgg
      541 atttcataaa caatagtcag aagcagtata gtttcataaa tgtcgaaggt atttcagttg
      601 aggacattcc tgatgataaa actctaaagt tctacttcta tggtcaggaa aaagaagaaa
      661 tttttaacta tcaggaagaa catgatctct ttatttatta tttagatcct ataactggca
      721 tagaaatacc tcttgaaaac acaataaaga ttgtagaaac tgaagaagaa acggatttaa
      781 ttataaaaat aggcgattat gtttttcaag acgtaaaaag acatcgtttt cctgatggga
      841 gtgtacagct tcattttggt gaaagcttta caatgtcttt tgacataaag aagaaacaat
      901 tcaaatttaa ctatactagg ccggatttgc tgtcaaaagc tataaagtgt actcaggtat
      961 ttcaagagct aggaaaaatc ggatatttta cccttaatgg taataaaata gagttagatg
     1021 aacggtcaat aaaggatatt tcttcacttg atttagaggc tgatataaag ggattgttaa
     1081 aaatttctaa ctttatgaaa aaaatgggta tacaaaaaga tgttgattta tcttgctttg
     1141 ataaacaatc tcaaagaaat ctaaatattc tttattcagg tcttgtctta aaaaagaaag
     1201 ttgctttaaa ttataatgaa tcgaaattac ttcacctaaa tattgctaac atccacatta
     1261 taactttata tagttttttg tcagataaaa atggaactat gatagacatt tttactgaaa
     1321 ctccttggtg ccgggaagga gaaactgaag atgaagatta tttagacatt tcaatttttg
     1381 aagtatttga accaaacgat tggctaaaaa ttgataattg taaaattgat tcagttattg
     1441 cctcgtatca aagattggta gataataagc tgaaatatga aggcgctgac cgtactattt
     1501 taaaaatagt tatcgctgca gacatggcag aagataagac taaaagagag ttgttactta
     1561 attgggcgca atgtctttct gactggaact taaaatactc aaaaaattgt gagatggcta
     1621 taataaatga ccttcaaata aaatctagag ttcgtaaatt aaacagcaaa gaaacagaga
     1681 cactaactaa tattttagta aatagtaatg ataactatga actttgtttc ggttcatcag
     1741 tgctattaaa atcgaaacca caagctgatt tgttttggaa taaactggat aatgagacaa
     1801 aagaaagata
//
LOCUS       DAVLBN010000125         1778 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLBN010000125 DAVLBN010000000
VERSION     DAVLBN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.125"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(615..1595)
                     /locus_tag="VXC24_002157"
     CDS             complement(615..1595)
                     /locus_tag="VXC24_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0494181.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT          556 a          371 c          332 g          519 t
ORIGIN      
        1 tttcaaaaaa ttcttttata taataatgtc cttgaaagta gtttcagctg aacatttata
       61 gtccataaaa agaaaacaga aactcatctg tttttatact caatgaaaat caaagagcaa
      121 actaagaagc tagccgcatg atgctcaaaa cactgttttg aggttgtaga taagactgac
      181 aaagtcagct caaaacaccg ttttgaggtg gcagatagaa ctgacgaagt cagtaacata
      241 tatacggcaa ggcgaagctg acgtggtttg aagagatttt tgaaaagtat taacacctac
      301 agacaagcct aacgatagca agaactaccc tactcgatag gtatcggctt ttgctttctg
      361 aaaaaaatta ttttaagcaa tttgacaaat ctagcaacaa aaaattctat aaatataata
      421 gattgaaact agaatagtac acatctactt ctaaaacatt gttagaaatc gatttgactc
      481 tcctgatcga tttgtcctgt tcttgtttca ttttactata tttccatgat aaaacgcata
      541 gtatcaagtt ttcttaatcc cctgatacta tgcgtgtttg taatttttaa gattttgtgc
      601 ttagagtcga ctccttattt tagatattta aaaggaatct cacttccaca gagccagttg
      661 tagacttggt cattgacaaa tacattcatg gcttcgtgag catactcagg catgatgcga
      721 taggttttat cgcaggtcag acgattataa atcgcaaact gggtaatggg atagcaaaca
      781 tcgtcgtcca agcccgtaat catcttaacc tcaccttgga tacgatgggc aagatttttg
      841 acatcgatat aggcaagggt cgccatgatt tcctcctctg tttcatggaa ggggtcgtga
      901 aacttgaaat aacggaaaag ttcgtcgtaa gcctcgctag tattaccaat ctcaatcacc
      961 cgtctgaagt ctgacaagaa gggataaatg gcaactgttt tctgaattcg aggattgagc
     1021 gctgctgcaa ctagagctag agcccctcct tgtgaggcac catagctaga aagacgcttc
     1081 tcatcaacct gagacagact agcaacaatt tcgaccaact ggtaaatatc cagataaaca
     1141 tccttataaa agaggtggtc ccgaccttcc acagcaccac ggataatatg ccccttcacg
     1201 gtatttccta aaggagaacg caagccgtct tgtgagtaac ctgactggcc ccgcacatcc
     1261 atggaaacaa caccgtaacc agctacggtg aagcccagca tgtcggccca gtcccagcca
     1321 cgtcccatat aaccatgaaa atggaagatt agtggaacct tctcctcact ctttggaaga
     1381 acaatgcgtg catagacctt tcctttcttg cttccttcaa atgttaactc atagcacttg
     1441 acttgaggaa tgtggaaatc tctttcctcc aagtggtagg atggaagcgt ggaaacattt
     1501 ttcacttccc catcccagaa atcatcaaag tcttccggaa cctcatccct tcctctatag
     1561 gtcttaattt cttctagcaa agctggattt ttcatagcat gctcctttta ttttgtaatc
     1621 gttaccacaa ctgtagcata tctatgtaat caatgcaaga aagaagggta aatagaaagt
     1681 gaatttagat tctttacttt taggatgatg ggctgaaagt agttttagaa acgaaaaaag
     1741 agcatttcgc tctctcttct gtttatacta gttttttg
//
LOCUS       DAVLBN010000126         1652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLBN010000126 DAVLBN010000000
VERSION     DAVLBN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.126"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(616..1608)
                     /locus_tag="VXC24_002158"
     CDS             complement(616..1608)
                     /locus_tag="VXC24_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0494182.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          558 a          280 c          206 g          608 t
ORIGIN      
        1 catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt
       61 ttttctacac aaaataggct ccataatatc tatagtggat ttacccacta caaatattat
      121 agaacccaaa aatgctctga aacactgatt tcaaggcatt ttttgttagt ttaaaattac
      181 tcccattctt cttttccaaa catacaatat atccaaaacc attcaaaata ctagattcta
      241 ttttttataa tatcactaaa tccacctaat tataggacgt tttcagattt ttagtcccgt
      301 cccagtccca gtaccggaga aatattgttt taatataata tctctttttg tcttctaagc
      361 tcttaaaagc aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc atattagggc
      421 aaataaaaag ctttaagaca gatgacaaat ctaagtcaaa taagaaagac catagcaaag
      481 gtgcagagag ataaatattg gcggtcttcg gactgccttt atttttttat ccatttttca
      541 aatcaaattt attcagacta tatatgcaca tatacactta aattcatata aaaacatggc
      601 ttgtaaaaaa ttactttaat cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa
      661 attacggact tcacttggaa gttttccctt gtatctttta taatagatag aaaatttgct
      721 ggcagatgaa tatccaacag attctgctat ctcttttata ggtagttcag tgtttaaaag
      781 aagagtttca gctacattca ttctttttct ttgagtgtac tctgtaatgc tttgacaata
      841 tttttcctta aataaatttt ttaatttagt accactcatt ttagatattt tttcaagcgt
      901 gccttgattt acattcgttg caaaatgatc atctaagaat cttgctacat cttcaagtgc
      961 tttatcatca tcaatttcaa ttttatattt ttttctattt aagtatgtgt caattactat
     1021 acttatccat tcatttgcct ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt
     1081 acaatttaat atttccattg ccactctttc taaggccttt gtaagtatta tttgattcgg
     1141 ttgaagcaag gttgaataaa aagattctgg attaatgtta atagatgcta aatgtttttc
     1201 tattagctct tttttaaaac caatggaaac agcaagataa caacaattct cgtgtaataa
     1261 aaaaacaaaa tcatctttta tattatcaaa atcaaaagta cataaagagt ttgcggtaat
     1321 agtttgatac ggattaaact tttctccgtt tgcactgaca atgtaacttg aataaattga
     1381 aacatagtct gacatactat aagtgctatt ttgaactact tcctctttga tataaaaatc
     1441 atgtatatcg ataatgaagc tgcctccttc ataaaaccaa tataggcctt ctgcataagt
     1501 tgaattctct tttttccaac aaaatgtatg acctgcactt gaatacttct cattgttttt
     1561 acattcatct actttcatat aatcttttac aaaatcataa tatgacataa cacactatcc
     1621 cttttagaca atattccaat tagccttatt aa
//
LOCUS       DAVLBN010000127         1592 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLBN010000127 DAVLBN010000000
VERSION     DAVLBN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.127"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..371
                     /locus_tag="VXC24_002159"
     CDS             <1..371
                     /locus_tag="VXC24_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000231994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494183.1"
                     /translation="IDYENKEIVTQQVYFENGLPDDRDIYCYDFDEIELMQSTGLKDK
                     NGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIGIVKQLEGSWVIDTGSDAVCLWTE
                     IEENEIIGNIYENKEFGGRK"
     gene            368..739
                     /locus_tag="VXC24_002160"
     CDS             368..739
                     /locus_tag="VXC24_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494184.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            812..1216
                     /locus_tag="VXC24_002161"
     CDS             812..1216
                     /locus_tag="VXC24_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0494185.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            1297..1379
                     /locus_tag="VXC24_002162"
     tRNA            1297..1379
                     /locus_tag="VXC24_002162"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1328..1330,aa:Tyr,seq:gta)
BASE COUNT          536 a          253 c          366 g          437 t
ORIGIN      
        1 ctattgacta cgaaaacaaa gaaatagtga cacaacaagt ttattttgag aatggtttac
       61 cagacgatag agatatctat tgttatgatt ttgacgaaat cgaactcatg caatcaacag
      121 gactcaaaga caagaacggc aaggaaatct ttgaaggcga tattgtacga actactagat
      181 ttttgggtag agctgacgaa attggcggtt tctatgagta tgacaaggaa tttataggga
      241 ttgttaagca gcttgagggt tcttgggtaa ttgatacggg cagtgacgca gtatgtttat
      301 ggactgaaat tgaagaaaat gaaatcatcg gcaacatcta tgaaaataag gagtttggag
      361 gacgcaaatg agaccttgta aatatccata ttcaggaaga agaaaaaaac aagaaacgcc
      421 gtcgccaata ttttctgcac gaccaatttt tgacgaagtt ccaattgtag aagaagttaa
      481 ggttgagttc ggagttgaag ctagtatggg gcgcatatat ccagaaacgt taatacattt
      541 agatatttct ggatacggaa atagagtgca ttcagtacat cgcttccccg gtattttact
      601 gagtgttggt gagtcaatcc aactaaagat gcttttctat aaaagactta gaaattttac
      661 tacagatcgt ttcttgacgt ttagagaatc tgattggaag ttctttatcc gggacctggt
      721 caacgaattt aagcattaaa aaaagccaag acactctctg cctcagctaa tagttctcgc
      781 aaagactatt atatcacaaa ggagacagag agtgaacaag gctaaagagc tcttgaaaga
      841 gttgcaggat ctggacatgg acatccaaag ccgtatagac gaaattaacg agcttgaggc
      901 aggtttgctc tcaagcccta aatggtccga ggttaaagtc caaggtggac agactagaaa
      961 agttgatgat gtctatactc agttggtagt gatgaaagag gctatagagc aggatactaa
     1021 agaggtcatt aacagaaaac ttgaattagg tagaatgatc aataggctta aaaatccaaa
     1081 gtacagggca gtattaagaa tgacttacat caacaaaggc accgctgata gcgtttgtta
     1141 tgatttgaat atgagtcgta caacctacta caggttaaaa aatgaggcgg tcttagcttt
     1201 ggaagaagtt atctaacctc atagtgagct tatgggactt tttggaacag cacggttcta
     1261 aaaatctgtt agaatggtag tatcaagaat tgaaaagaga ggtctcagaa ttggtagatg
     1321 gttacctgta atgtcagggg gctgtaatgg ccttggaggt tcaagtcctc ccctctcctt
     1381 tgagtgtttg tgtcccagaa tgagttaaat cttctgggtg gggattcaca tatcactcat
     1441 taactcctat cactcattaa cttaaaaatg gttgcggaag cgactggacc tcgcatgatt
     1501 gcgtagctaa ttatattccg gataagttat aagctagagg gtttgattcc ctcagaggtt
     1561 ttaaagacta caaaaaataa aaaagaagtc aa
//
LOCUS       DAVLBN010000128         1579 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLBN010000128 DAVLBN010000000
VERSION     DAVLBN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.128"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            356..>1579
                     /locus_tag="VXC24_002163"
     CDS             356..>1579
                     /locus_tag="VXC24_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0494186.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDVY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRA"
BASE COUNT          476 a          284 c          358 g          461 t
ORIGIN      
        1 gtataaaaca aaaaatcaat tctaacagtt ttatatcaga ataataaata aaaaagcgat
       61 attctagact gtatcaatcc ttttccatta taggagcaac agagtgggag tagtcatcta
      121 aggactaatt tatatatttt tacgagtcag tatcttggga tactggtttt tactttttta
      181 gactttttga ctacttgtta aaactggggt aattttcgac tgtttaatag ttattatgca
      241 aagtctaaaa gattagaatt gtcaaaacaa tccgtctagg cttgatttta tcctttattt
      301 actataaaat gagaaggaaa aatgtcaaac ttttatattg caaataggag aaatcatgac
      361 aaaaacatta aaacgtcctg aggttttatc acctgcaggg actttagaga agctaaaggt
      421 agctgttcag tatggagcag atgctgtctt tatcggtggt caggcctatg gtcttcgtag
      481 ccgtgcggga aactttactt tcgaacagat ggaagaaggc gtgcagtttg cgaccaagta
      541 tggtgccaag gtctatgtag cggctaatat ggttatgcac gaaggaaatg aagctggtgc
      601 tggtgagtgg ttccgtaaac tgcgtgatat cgggattgca gcagttatcg tatctgaccc
      661 agccttgatt atgattgcag cgactgaagc accaggcctt gaaatccacc tttctaccca
      721 agccagtgcc actaactatg aaacccttga gttctggaaa gagctaggct tgactcgtgt
      781 cgttttagcg cgtgaggttt caatggaaga attagctgaa atccgcaaac gtacagatgt
      841 tgaaattgaa gcctttgtcc atggagctat gtgtatttca tactctggac gttgtactct
      901 ttcaaaccac atgagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg
      961 gaaatacgac ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat
     1021 tccagaagaa ttttcaatgt cagccgttga catgtctatg attgaccata ttccagatat
     1081 gattgaaaat ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta ttcactacgt
     1141 atcaacagta accaactgct acaaggcggc tgtggatgtc tatcttgaaa gtcctgaaaa
     1201 gtttgaagct atcaaacaag acttggtgga cgagatgtgg aaggttgccc aacgtgaatt
     1261 ggcaacaggt ttctactacg gtataccatc tgaaaatgag cagttgtttg gtgctcgccg
     1321 taaaattcct gagtacaagt ttgtcgctga agtggtttct tatgatgatg cggcacaaac
     1381 agcaaccatt cgtcaacgaa acgtcattaa cgaaggggac caagttgagt tttatggtcc
     1441 aggtttccgt cattttgaaa cctatattga agatttgcat gatgccaaag gcaataaaat
     1501 cgaccgcgct ccaaatccaa tggaactatt gactattaaa gtcccacaac ccgttcaatc
     1561 aggagacatg gttcgtgca
//
LOCUS       DAVLBN010000129         1556 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLBN010000129 DAVLBN010000000
VERSION     DAVLBN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.129"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            73..985
                     /locus_tag="VXC24_002164"
                     /pseudo
     CDS             73..985
                     /locus_tag="VXC24_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1018..1358)
                     /gene="tnpB"
                     /locus_tag="VXC24_002165"
                     /pseudo
     CDS             complement(1018..1358)
                     /gene="tnpB"
                     /locus_tag="VXC24_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          491 a          279 c          320 g          466 t
ORIGIN      
        1 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgt actgttatag
       61 attcaataca ctataaactg taatcaaaca acgatttggc gaaatgtaaa aaaatatgag
      121 gagttcggac tcgactctct ccttcaagaa acacgtggtg gtcgtaacca tgcatatatg
      181 acggttgagg aagagaaagc ctttcttgcc cgtcatttga aggctgcaga ggcaggagaa
      241 tttgttacaa ttgatgcctt atttcaggct tataaaaagg agttaggtcg ttcctacaca
      301 cgtgatgcct tctatcaact gttgaagcgc catggttggc gaaatattat gccacgtcca
      361 gaacatccta agaaagcaga cgctcaaacc attgtcgcgt ctaaaaataa aatctcaatt
      421 caagaagaaa agaaagcgct ttaaaaccag tagacgtttt cataaggttt gcttgatgta
      481 ccaagatgag gctggtttcg gtagaatcag taaactggga tcttgttggt ctccaatagg
      541 agtaggtcta catgtccata gtcactatat acgagaattt cgctattgtt atggagctgt
      601 tgatgcctat acaggcgaat catttttctt aatagctggt ggatgtaata ctgagtggat
      661 gaacgccttt ttagaagagc tttcacaagc ttatccagat gattatcttt tactcgttat
      721 ggacaatgct gtatggcata aatcaagtac cttaaagatt ccgactaata ttggctttgc
      781 atttattcct ccatacacac cagagatgaa ccccattgaa caattgttga aagagattcg
      841 taaacgtgga tttaagaata aagcctttcg aactttggaa gatgtcatga atcaactcca
      901 agatgttata caaggactgg agaaggaggt gataaagtcc atcgttaatc ggagatggaa
      961 tagaatgctt tttgaaagca gatgagtata aaaagaaagt cctcatttca atagaaatca
     1021 cgactttctg atggatttat ttttggagtg atagaaaagc ccgtcataag ccagtctact
     1081 tgttcaggtg tgagagcttt gacatccttt tctgtattgg gccaagtcag tctgccgttc
     1141 tcaaagcgtt tatatagtag ccaaaatcct tgaccatccc agtaaagggc tttaaagcgg
     1201 tctttacgtc caccacaaaa gagaaagact tgaccggaga aaggatccaa ttcaaagtgg
     1261 gttttaacta cataggctaa tgagtctatt ccctgcctca tatctatctt gctacaaaca
     1321 aggtgaactt gacctaaatc acttagttga attatcatag tacaatacct ttcctccgat
     1381 aattattttt tatctagtat actggaagtt ggggaattag gatagatacc ttgttatgac
     1441 gcgcttacgt aacttgtaac tagctgccta gtttgatctt tgcttcttca ttgattagca
     1501 gtagatttca aaatgataaa aacgcataat agtgggtgta gaatgaactg ccttcc
//
LOCUS       DAVLBN010000130         1470 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLBN010000130 DAVLBN010000000
VERSION     DAVLBN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.130"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..66
                     /locus_tag="VXC24_002166"
     CDS             <1..66
                     /locus_tag="VXC24_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV0494187.1"
                     /translation="LLSDKEKLSPKKWNEEKILLM"
     gene            392..565
                     /locus_tag="VXC24_002167"
     CDS             392..565
                     /locus_tag="VXC24_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494188.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            751..1278
                     /locus_tag="VXC24_002168"
     CDS             751..1278
                     /locus_tag="VXC24_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV0494189.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1405..>1470
                     /locus_tag="VXC24_002169"
     CDS             1405..>1470
                     /locus_tag="VXC24_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0494190.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT          775 a          191 c          226 g          278 t
ORIGIN      
        1 ctcctatcag ataaggaaaa actaagtcct aaaaagtgga atgaagaaaa aattctttta
       61 atgtaaaatc ttgaagaaat aaataaagaa aaagacaaga taaaagatga ataccaggaa
      121 attaatcata taaaatattc agtagatttt gtaaacaaag aacttggtat agatttatcc
      181 atagaaatag ataagctaat aaaacaggga gaaaaaccaa gtgtaatagc acagattaaa
      241 aagttccaag accaagtcaa taaagataat gaatacagag aaatgatgaa aaacaagaaa
      301 atggatcaag aaagataaga cctggtaaaa atatcttatc caagctataa tatgaccaaa
      361 caactaaagt cagatctagg aggtaataga gatgaataaa aggcaagagc taatagatga
      421 actcataaaa gcaaatgaag atggaacata caaaacctat aaaagcacag aagaaataaa
      481 agcaatgaac aatgaagaaa tacagattat atattccaac atgaaaaact atctatcaga
      541 caaaagaaca cacataaact attaaaggtg gaaaggtagt gtaagctatt tttaaaagta
      601 taaaaggtac aaagacctaa gaaatatata aaaacatcaa aataaagtat tccaccacca
      661 agaacaataa aataaaaaca agcaaaggga agtatagaaa aattaaaacc tatacttccc
      721 ttttttaatt caaacaaagg agagaaaagc atgataaacg aagaaataag caaggaagca
      781 ggtcaagcag cacaaaccat aatatcatac acaataaagg caacaaaaga atcaatcaat
      841 ttagaaaaag aaataagaaa aaagatgaat gaaactttag aaaaagcaaa tggaaactta
      901 aaaagtctta tgggcgatga aatgaaaata aaagatctct acaagaaagg acaactagaa
      961 aatataagca tagatcaaat cgacctcaaa gacttaaaaa aagaactaaa caaacttgga
     1021 gtaagtttct cagtaatgaa aaacaaagaa agcaaaaact atgaaatatt cttccaagcc
     1081 aaagacataa aagtaatgga atatgccttt aagcaagtca tagccaagga aaataaaaaa
     1141 gaaaaagaaa gtatcctaaa acaaataaag aaatacaaag acctatccaa aaacaaagat
     1201 aagacaaaag aaaaaggaaa aaggaaagta aaagaaaaag taaaaccaaa caaaaaagat
     1261 atgaccagag aaatctaaag ggagtaacga aaagttacac ccttaaataa ccataataac
     1321 aagacttccg aaaaacagaa gtccagaatt ccgaaaatcg gaaatcaaga atttcgatta
     1381 tcgaaaatca agaaaggagc agatatggca acaaacaaaa gatactattg gataaaatta
     1441 aaagaagaat ttttcacaga caaaaggata
//
LOCUS       DAVLBN010000131         1467 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLBN010000131 DAVLBN010000000
VERSION     DAVLBN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1467
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.131"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..270
                     /locus_tag="VXC24_002170"
     CDS             <1..270
                     /locus_tag="VXC24_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV0494191.1"
                     /translation="EESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAVFESIFEES
                     IDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            580..>1467
                     /locus_tag="VXC24_002171"
     CDS             580..>1467
                     /locus_tag="VXC24_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV0494192.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDI"
BASE COUNT          686 a          184 c          258 g          339 t
ORIGIN      
        1 gaagaaagca ttaagcaatt acaaaatcaa aaaagacagt tgaagaaaaa acttaatgaa
       61 caagaaagaa aagcaagaaa caaaagactt atagaaaaag gtgcagtgtt tgaaagtatt
      121 tttgaagaaa gtattgattt aacaaaagat gaattttata agttaataaa aacgttaaat
      181 gatgaagaaa taagattaaa cataatggaa attttagaag aaagaataga tgataatgta
      241 gaaaaatcat ctaaagatga aataacataa ttgtcccttg gttacaaggg cgcaattata
      301 caccctaaag ggtgcttgcg tcctgcggag tcaaaccctt gcagggagca acaaccattc
      361 gctttttaaa agtcaagggt aaataaactc gctaaggctc gcccttgact tttaaaattt
      421 gaaatgaaag taacaattaa gccgacatac tgaaacaaca aaaattaatt cagtagtcgg
      481 ctttttttat tctatcattt caaaacgctc attcacaaag aggatataaa aaaactatta
      541 agcctccacc taaaacaaca aagaaaggaa gtgataaaaa tggcagacag ttttcatttt
      601 tcagtaaaca taatatcaag aggaaaaggc aaaagtgcag tagcaagtgc agcatatata
      661 agtggagaaa aaataaaaaa tgaatgggac ggagtaaccc atgactacac aagaaaagaa
      721 aaaatattag taaaaaatat aatattgcct gatcatatac caaaagaatt taatgatagg
      781 tctaccttat ggaataaagt agaaatggca gaaaaaaatt ctaatgcaca actagcaaga
      841 caattcataa taggactacc aaaagagtta tctttaagtg aaaataaaaa cctggttgaa
      901 agatatataa aagaaaattt aacatcacaa ggaatgatag tagattatgc aattcatgat
      961 gagagtcaag ataaaaatgg aaatatccat tgtcatataa tgaccataat gcgaccaata
     1021 aacgaaaaag gagagttctt agccaagtca aaaaaagaat atatcctaga tgaaaaagga
     1081 gaaaaagtat taaacaaaaa tggaaaacca aagacaagaa aagtagaact aacaacctgg
     1141 aacgatacag gcaatgtaga acaatggaga gaaaattttt cagatctttg taacaaatat
     1201 ttagaaagag caggagcaga aaaaagagta gaccatagga gttttaaaag acaaaattca
     1261 gattatctac cgacaatcca tttaggatca gcagcaagtg caatggaaag aaagggaata
     1321 gaaactgaca agggaaacta taatagagaa ataagaaaat ataatcaact tgtaaaaaca
     1381 ataaaagaag agataaaaac attaaagggt tggataggaa atttattaga taacttatct
     1441 actgcttatg aaaaatttaa ggatatc
//
LOCUS       DAVLBN010000132         1447 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLBN010000132 DAVLBN010000000
VERSION     DAVLBN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.132"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..662
                     /locus_tag="VXC24_002172"
                     /pseudo
     CDS             1..662
                     /locus_tag="VXC24_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(697..1447)
                     /locus_tag="VXC24_002173"
                     /pseudo
     CDS             complement(697..1447)
                     /locus_tag="VXC24_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          449 a          245 c          293 g          460 t
ORIGIN      
        1 agatagactt aaaaactatc ttactgacaa tccagacgct tatttgactg aaatagcttc
       61 tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc aaagctatgg gctacactcg
      121 aaaaaaagaa ccacacctac tatgaacaag acccagaaaa agtagcctta tttcttaaga
      181 attttaatag tttaaagcac ctagcacctg tttatattga tgaaacagga ttcgatactt
      241 atttttatcg agaatatggt cgctcattaa aaggtcagtt aataagaggt aaagtatctg
      301 gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgag ttaatcgctc
      361 caatgactta cgaagagatg gtgacgagcg acttttttga agcttggttt cagaagtttc
      421 tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga ttccatagaa
      481 tgggtaagtt agaactttta tgcgaggagt ttgggcataa acttttacct cttcctccct
      541 actcacctga gtacaatcct attgagaaaa catgggctta tatcaaaaag aacctcaaaa
      601 aggtattacc aagttgcaat accttttacg aggctctttt ctcttgttct tgtttcaatt
      661 gactatatta gaggcgagac atttttcggt tctttgtcaa ctgtagtggg ttgaagaaag
      721 cgaagatcta gaaaggacaa atttcgtcct ttcttttttg aagttttcaa agttcctaaa
      781 accaaaggca ttgtgcttga taagtttgat gagattattg gtggcttcca gtttggcgtt
      841 ggaataaggt aattgaaggg cgttgacgat tttctcttta tctttgagga aggttttaaa
      901 cagagtctga aaaagaggtg gaaaagcaag agctgataga gattatagct gatagagatt
      961 atagtggtgt ttcaagtctt cgaatagctc aaaagtttat ctagaatttc tttattagtc
     1021 aagtgcatac gaaaagtagg gcgataaaat cgtttatcac tcagtttctg actatcttgt
     1081 tgaatgagct ccagtagcgc ttgatagcct tgtattcatg ggatttcgga tgatggcttg
     1141 tgttctgctc tcaagaacag ttatgatatt gagcttatca aagtcctgag caataaagct
     1201 catctctatc tcccgattga aacagtcact ccccagactg tttcaacgtc ctaggacata
     1261 atctcaggaa gacgcgaaaa atcatgctca aagtgaaaat cattgatctt gcgaatgaca
     1321 gttgaagttg aaatagacaa ctgatgatca atgtcggtca tagaaatctt ttcaattaac
     1381 ttttgagcaa tcttttggtt gataatacga gggatttggt gattcttctt gacgatagaa
     1441 gtttcag
//
LOCUS       DAVLBN010000133         1438 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLBN010000133 DAVLBN010000000
VERSION     DAVLBN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.133"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(101..653)
                     /locus_tag="VXC24_002174"
                     /pseudo
     CDS             complement(101..653)
                     /locus_tag="VXC24_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(729..956)
                     /locus_tag="VXC24_002175"
     CDS             complement(729..956)
                     /locus_tag="VXC24_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0494193.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            984..1169
                     /locus_tag="VXC24_002176"
                     /pseudo
     CDS             984..1169
                     /locus_tag="VXC24_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1264..1438
                     /locus_tag="VXC24_002177"
                     /pseudo
     CDS             1264..1438
                     /locus_tag="VXC24_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          447 a          304 c          264 g          423 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatgt
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa gctcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttca aaatagtctt aaaggtttct tcatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga gatgttcttg acgtttctgt agtcgttcat cagctggcaa agcctcccag
      481 tctctttcca aggaaaataa ctgatcacaa taagctaaac ctttagctcc taaggatgat
      541 ttatctgctt gcttgggggt cgcttcaaaa aatttccttc tcacatgcgc ccaacatcca
      601 acaagttcag cttcttccag ttgacgataa gcttctagca gttcgcagtt taccaagctt
      661 agcgtcgcct tgctcctaaa ccttggactg ctatcgcata ggcagaacta gaggactaaa
      721 gtcctaagtt actgccgcaa catatcacaa tgaacatagc cagaataatc tcctaggaat
      781 tcttgtacta ccgaaccact ccgactctga tcatgatggt acagcgtgat tgcttgattc
      841 tcaactttcc cagacaaaaa ggtccaatag taggtcagat ggctatgact ctctagaacc
      901 cgataagaag tttcatccgc atgaagtaag ggctgagtca atagtctctc tcgcaagagg
      961 ttataaaggg gctttaggaa taggagcttt cacaagctta tccagatgat tatcttttac
     1021 tcgttatgga caatgctata tggcataaat caagtacctt aaagattccg actaatattg
     1081 gttttgcatt tattcctcca tacacaccag agatgaaccc cattgaacaa gtgtggaaag
     1141 agattcgtaa acgtggattt atagtaaaat gaaataataa caggacaaat cattcaggac
     1201 agtcaaatcg atttctaaca atgttttaga agcagaggtg tactattcta gtttcaatct
     1261 actatagata aacttttgag ctattcagaa gacttgaaac accactataa tctctatcaa
     1321 ctcttgcttt ttcactttca gaataaggag cctgacaaat ttttcggact cattgaggac
     1381 aatctgaatc aggttcatcc tctaaaacct tcctcaaaga taaagagaag attgtcaa
//
LOCUS       DAVLBN010000134         1301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLBN010000134 DAVLBN010000000
VERSION     DAVLBN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.134"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..213)
                     /locus_tag="VXC24_002178"
     CDS             complement(<1..213)
                     /locus_tag="VXC24_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0494194.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGHGNRNRKPKHAIPDEIKER"
     gene            377..529
                     /gene="rpmG"
                     /locus_tag="VXC24_002179"
     CDS             377..529
                     /gene="rpmG"
                     /locus_tag="VXC24_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0494195.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            539..715
                     /gene="secE"
                     /locus_tag="VXC24_002180"
     CDS             539..715
                     /gene="secE"
                     /locus_tag="VXC24_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0494196.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            770..>1301
                     /gene="nusG"
                     /locus_tag="VXC24_002181"
     CDS             770..>1301
                     /gene="nusG"
                     /locus_tag="VXC24_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0494197.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          410 a          204 c          258 g          429 t
ORIGIN      
        1 acgttctttg atttcatcag ggattgcatg ttttggtttt cgatttctgt ttccgtgtcc
       61 gtgtctgaag gcttcttttc ctttctgttg ataggctagt aacagacgat tgatttgtct
      121 ttcagaaaga ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc
      181 ttttatcaca agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact
      241 attctaccaa atgggacatt ttcacgttcg atttactaaa gacattatca cattcgaatc
      301 acaatagtca atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg
      361 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
      421 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
      481 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
      541 gcgttttatt ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga
      601 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
      661 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
      721 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
      781 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
      841 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
      901 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
      961 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     1021 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     1081 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     1141 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     1201 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     1261 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAVLBN010000135         1296 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLBN010000135 DAVLBN010000000
VERSION     DAVLBN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1296
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.135"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            50..238
                     /locus_tag="VXC24_002182"
                     /pseudo
     CDS             50..238
                     /locus_tag="VXC24_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            275..>1296
                     /locus_tag="VXC24_002183"
     CDS             275..>1296
                     /locus_tag="VXC24_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV0494198.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRT"
BASE COUNT          463 a          148 c          231 g          454 t
ORIGIN      
        1 gttgtttcta tactgctttc tatattatat atgagaggaa ggacgaaata tgttctacgt
       61 aaatagttat gtttttgctt ataaaaaaga aggtataatg tatttgcgtg gtcggagtat
      121 gcgggaaata gctatagaac ctcaaatttc gcaagaattt atcaacgatc tatttaatag
      181 ttgtaaggaa ctattagaga tagaagaagt attaggtagt aaactaacat ttgaactatt
      241 aaatgaacaa attttaattt cggatgagat agatattgat agtagatatt ctagaactaa
      301 aggttactat tcgttatttt ataatgaaga gtataataaa atacagaata aaacagtatt
      361 agtattagga gccggagcct taggatgtta tatatctcta agtctaagta tgtatggagt
      421 gaggaaactt attgtcgctg attacgatat aatagaacca tcaaatttaa ataggcaaat
      481 tctttataca gagtcggatg ttggtaagga gaagattaat gttctttctc aaaaaataca
      541 caagtataat tcagatgttc aggtagtacc tatttctatt aaagtttctt cagtagaaga
      601 attagaaaac attgttgcgg aatatgggag tatagatttt atcgttaaag caattgatac
      661 gcccattgat attataaaaa ttgtcaatca atttgctgta tcgcataaga tatcctacat
      721 atcaggaggg tttaatggat gctatcttat tattgataat atatatatcc ctaccatcgg
      781 ttcttgcttt gcttgtcgga atataaacaa agatataaat aagtacactt tatctgataa
      841 gacaaagtgg ccgactacac cagagatgcc tgctattttg ggagggataa tgactaattt
      901 aataattaaa atatttctgg gatgttataa tgaaatccta atagataacg cttacgttta
      961 taatatgaga aatcatgctc taagtcaaga aaaatatgtt ctggaaaacg gagaatgtcc
     1021 aatttgtaaa aaaaataata aagtgaaaga taacaatatt agagcgaaaa catttattcg
     1081 ttcagtttgt ttttgcttat tatcaggagg agtagctttt ttatctgcta ttgggcagtt
     1141 cactgttata gaaacacaat taatagtatt gttcttgggt attatttttg ctatatatta
     1201 tgcttactac aataaaaata ttcaaacatc attggaaaat atagtatggc ttttttcatc
     1261 gtttgagatt ttatttttgc ttgttaattt tagaac
//
LOCUS       DAVLBN010000136         1002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLBN010000136 DAVLBN010000000
VERSION     DAVLBN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.136"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..680)
                     /locus_tag="VXC24_002184"
     CDS             complement(<1..680)
                     /locus_tag="VXC24_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494199.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLGAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILE"
     gene            complement(667..>1002)
                     /locus_tag="VXC24_002185"
     CDS             complement(667..>1002)
                     /locus_tag="VXC24_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494200.1"
                     /translation="GGKPLDFWDLTVLEIREMIESYNRVKTQERKEKIIDSYRLSQMI
                     SNHVSLLLSNDAKIVEFWEYAPELFVEEQQAVELERQKQALLLHKERMREFAERHNRK
                     RKEEVNGNS"
BASE COUNT          254 a          252 c          186 g          310 t
ORIGIN      
        1 tgctccagga tagccataag acggatttgt tgctgggttt gaaagtcgag ttggtcccaa
       61 ctttgaccat ttgagaaacg tttaaaagct tcagtggact taatcatagc cacattgacg
      121 ttgattccta gatcctcaat cgcttcggtg ttccctagta gacctgagcg aatccgctcc
      181 ataacgtctg taatcgtgcg ccctgaacct tcagcaacaa ctgccgatgt ctgcaacatc
      241 ttagcggtat aggcgcctag cttgttggta tctttgataa acccagaaaa taagtttgag
      301 tagaccgcac cgtagttagt agcctcaccc acacccatat tcatagcgtt ggcgttatcg
      361 ttaacccatt ttaagaaaga ttgcgaactc tcgcccatct gtcgcttgat ttggttcata
      421 gacgctgata cttcaagagc cgtctgcgtt gaatacatcc caacatcaag taatttctta
      481 ccaaggattg caaaaccagc gaacttagcc agcttaccaa acgcactacc gattgagttc
      541 gactgttcac gaactttggc agtggcattt ttcactcggt cagatgttcc tttgacctga
      601 ttctcgactt ctttcatctt tttcctgaaa ggcgctatct cagcgtcaat catgactttc
      661 aattcatcaa gagttgccat ttacttcctc cttccttttt cgattatgtc tctctgcaaa
      721 ttcacgcatc cgttccttat gcaacaaaag tgcttgtttc tgtcgttcca gttctaccgc
      781 ttgttgttct tctacaaata actcaggcgc atactcccag aactcaacaa tcttagcgtc
      841 attggacagt aataaagaaa cgtgattgga aatcatctgc gaaagtctgt atgagtcaat
      901 aatcttctct ttacgctctt gggttttgac acggttgtag ctttcaatca tttctctgat
      961 ttcaagcacc gtcaaatccc aaaaatcaag aggcttgcct cc
//
LOCUS       DAVLBN010000137         1002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLBN010000137 DAVLBN010000000
VERSION     DAVLBN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.137"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..680)
                     /locus_tag="VXC24_002186"
     CDS             complement(<1..680)
                     /locus_tag="VXC24_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494201.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILE"
     gene            complement(667..>1002)
                     /locus_tag="VXC24_002187"
     CDS             complement(667..>1002)
                     /locus_tag="VXC24_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494202.1"
                     /translation="EGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYRLSQMI
                     SNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAERHNRK
                     RKEEVNGNS"
BASE COUNT          245 a          251 c          187 g          319 t
ORIGIN      
        1 tgttccagaa tagccataag gcggatttgt tgctgggttt ggtaatccaa ctgttgccag
       61 ctctgtccgt ttgcgaactt cttaaaggct tcagtggact caatcatagc cacgttgacg
      121 ttgattccta ggtcctcaat cgcttcggtg ttccctagta aacctgagcg aatccgctcc
      181 ataacgtctg taatcgtgcg ccctgaacct tcagcaacaa ctgccgatgt ctgcaacatc
      241 ttagcggtat aggcgcttag cttgttggta tctttgataa atccagaaaa taagtttgag
      301 tagactgcac cgtagttggt agcctcaccc acacccatat tcatagcgtt ggcattatcg
      361 ttaacccatt ttaagaaaga ttgcgaactc tcgcccatct gtcgcttgat ttggttcata
      421 gacgctgata cttcaagagc cgtctgcgtt gaatacatcc caacatcaag taatttctta
      481 ccaaggattg caaaaccagc gaacttagcc agcttgccaa acgcactacc gattgagctc
      541 gactgttcac gaactttggc agtagcattt ttcacttggt cagatgttcc tttgacctga
      601 ttctcgactt ctttcatctt cttcctgaaa ggcgctatct cagcgtcaat catgactttc
      661 aattcatcaa gagttgccat ttacttcctc cttccttttt cgattatgtc tctctgcaaa
      721 ttcacgcatc cgttccttat gcaacaaaag tgcttgtttc tgtcgttcct gttctactgc
      781 ttgttgttct tctacaaaca actcaggcgc atattcccag aactcaaagg ccttggcatc
      841 tttggataac aataaagaaa cgtggttgga tatcatctgc gaaagtctgt atgagtcaat
      901 aatcttttct ttacgctctt ggattttgac acggttatag ctttcaatca tttctctgat
      961 ttcaagtacc gtcaaatccc aaaaatcaag aggcttgccc tc
//
LOCUS       DAVLBN010000138          892 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLBN010000138 DAVLBN010000000
VERSION     DAVLBN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.138"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..404)
                     /locus_tag="VXC24_002188"
     CDS             complement(<1..404)
                     /locus_tag="VXC24_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEV0494203.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDIGSL"
     gene            complement(382..861)
                     /locus_tag="VXC24_002189"
     CDS             complement(382..861)
                     /locus_tag="VXC24_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0494204.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDISD"
BASE COUNT          245 a          226 c          142 g          279 t
ORIGIN      
        1 agactaccga tatcgactgt aatagatgta attttgagtt catcatccaa accacggaat
       61 aggatttttt gaccagtcgc ttttatggtt atttcaggca aagactcgtt aaatttaaac
      121 aaatgagtca cacccaacac attacacgcc catttaaaat ccgtataagt tgattgcttg
      181 ttggtattcg agtatctacg aataacaagc aagttggccc agggatactt caaaagacgg
      241 ataacataat tcaaagcggt tgtcttggac ttcttcgaac cacgggaccc tttgactaca
      301 cgataaagac ttcttgagcg ccagaactgt ccgtatccag ctcctactgt cttaggtaag
      361 tcaacgacaa tatcgttttg tttaatctga tatgtctgac tcatttgcaa acaccaccgt
      421 tccagaaaca tccgcctcta ccttatccgt ccaaagccta tgccgtttac caagaagttc
      481 agccgccttg attctatctt tagctcctac atctatatcc gtaatcgtct gccctagttc
      541 tccaatgctt atcaaggtct gttcttgcgt ctctcctcgc atgactgaag ttagataacc
      601 taagacctct tgctgatccg caatcttttc agaatcaagc tgtttcagtc gttcatctat
      661 atagctttta atcttaggat tctttagtaa cttatgtcct tcaacgcctg ccactctatc
      721 actagaaaca cgataacctg ctttcttata ggcttccgtc gcattacctg agatgatgta
      781 ctcatctgca aatctctttt gttttattct caatccactc aattttccat caccaccctt
      841 cgaataatca aaaaaagcca cacgatgtgc gaccttcttg caaggcgact ac
//
LOCUS       DAVLBN010000139          891 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLBN010000139 DAVLBN010000000
VERSION     DAVLBN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.139"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            70..510
                     /locus_tag="VXC24_002190"
     CDS             70..510
                     /locus_tag="VXC24_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0494205.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            488..>891
                     /locus_tag="VXC24_002191"
     CDS             488..>891
                     /locus_tag="VXC24_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEV0494206.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWHSRSLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSL"
BASE COUNT          286 a          145 c          222 g          238 t
ORIGIN      
        1 gtagtcgcct tgcaagaagg tcgcacatcg tgtggctttt ttgattgttt gaaaggtggt
       61 gatggaaaat tgagtggatt gagaataaaa caaaagagat ttgcagatga gtacatcatc
      121 tcaggtaatg cgacggaagc ctataagaaa gcaggttatc gtgtttctag tgatagagtg
      181 gcaggcgttg aaggacataa gttactaaag aatcctaaga ttaaaagcta tatagatgaa
      241 cgactgaaac aacttgattc tgagaaaatt gcagatcagc aagaagttct tggttatcta
      301 acatcagtaa tgcgaggaga gacgcaagag cagaccttga taagcatcgg agaattgggt
      361 caaacgatta cggatattga cgttggagca aaagacagaa tcaaggcagc cgaactatta
      421 ggaaaacgtc ataggctttg gacagacaaa gtagaggcag acgtttctgg aacggtggtg
      481 tttgcaaatg agtcagacat accagattaa gcaaaacgat attgtcgttg acttacctaa
      541 gacagtagga gctgggtacg gacagttctg gcactcaaga agtctttatc gtgtagtcaa
      601 agggtcccgt ggttcgaaga agtccaagac aaccgcttta aactatgttg tccgtctttt
      661 gaaatattcc tgggccaact tgcttgttat tcgtaggtat tcgaatacaa ataagcaatc
      721 aacttatacg gattttaaat gggcgtgtaa tgtgttgggg gtgactcatt tgtttaaatt
      781 caatgagtct ttgcctgaaa taaccataaa agcgactggt caaaaaatcc tattccgtgg
      841 tttggatgat gaactcaaaa tcacatctat cacggtcgat gtcggcagtc t
//
LOCUS       DAVLBN010000140          891 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLBN010000140 DAVLBN010000000
VERSION     DAVLBN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.140"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..651)
                     /locus_tag="VXC24_002192"
     CDS             complement(<1..651)
                     /locus_tag="VXC24_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEV0494207.1"
                     /translation="MLHPIFIIRRSWDGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRI
                     EVTQAINFHKKHSISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTS
                     EDKLNFSSFTMGDNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVST
                     PMNLSKIDTVPRITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKI"
     gene            complement(710..>891)
                     /locus_tag="VXC24_002193"
     CDS             complement(710..>891)
                     /locus_tag="VXC24_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494208.1"
                     /translation="YSGSDITPVYSLGSGSRIVMYYNGGGDNYIGSGTRLAMAPQFGN
                     HVRIHTSGSWSPDSY"
BASE COUNT          301 a          176 c          123 g          291 t
ORIGIN      
        1 tattttattt acaaaccttt gcaataacac aaaaaaatta gatacgtgta atccatctcc
       61 cattccatga ttaatttgta aattcactgt acaaaaatat ctttggttct cttgaataac
      121 ttttccccac gttattcgag gaactgtatc aatttttgaa agattcatag gagtgcttac
      181 atgtaaaaaa tcaatccatg gaacacaaga aagataagca atgttattct tgtcaatatt
      241 tggtttttgc ccttcttctg ccttctgttt atttatgttg aacgcagaaa caaattcaat
      301 taaattatct cccatcgtaa atgaagaaaa attaagctta tcttccgatg taagggtagt
      361 gaaagaacaa cctctttgat tgtattgcca gacaatcttt ccgtcggtat ccattagtaa
      421 ttctggaata gaatttattg cactcataac acaccacgat attatggcat aaagtgatat
      481 cgaatgtttt ttatgaaaat tgatagcctg cgttacttct attcgtgaac tcatagataa
      541 ataaggaaca tccattttat tgaaaaagtc aaattcttca ttccttttcc actctgataa
      601 atgaaaaatt ccatcccaac tcctccttat aataaaaata gggtgtagca ttcttttttc
      661 atgctacacc cacaatcaac catctttaag gcttactctg acaagtaagt taataagaat
      721 ctggactcca agaacctgaa gtatgaattc ttacatgatt tccaaattgt ggcgccatag
      781 ctaatctagt accagaacca atataattgt caccacctcc attatagtac atgacaatcc
      841 tagagccaga ccccaatgaa tataccgggg taatatctga cccactatag g
//
LOCUS       DAVLBN010000141          866 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLBN010000141 DAVLBN010000000
VERSION     DAVLBN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.141"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..265)
                     /locus_tag="VXC24_002194"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VXC24_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(500..811)
                     /locus_tag="VXC24_002195"
     CDS             complement(500..811)
                     /locus_tag="VXC24_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494209.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          275 a          171 c          138 g          282 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga ctttgcataa
      301 taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat accagataaa
      361 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
      421 tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac
      481 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
      541 taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta tatgttagta
      601 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
      661 caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac tttttacaat
      721 catagcattg taaagcaata atatccaact tgctatggta atgaatgcat cttgtttgct
      781 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag cacgaactgt
      841 gacgctggtt ccatcttcct tataaa
//
LOCUS       DAVLBN010000142          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLBN010000142 DAVLBN010000000
VERSION     DAVLBN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.142"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..792
                     /locus_tag="VXC24_002196"
     CDS             <1..792
                     /locus_tag="VXC24_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HEV0494210.1"
                     /translation="FDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKK
                     MEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEA
                     NTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCY
                     IPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQK
                     KERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          299 a          200 c          136 g          203 t
ORIGIN      
        1 tttgacaaac aagagacctt gaatgcctac taccatgtcc tcgaacaaat cttagccaat
       61 cacggcattc cccttcaaat gaaaactgat aagagaacgg tctttaccta tcaagcatcc
      121 aactctaaga aaatggagga cgacacctat acacaatttg gatacgcctg tcaccaacta
      181 gggattctcc ttgagaccac ctctatccct caagctaaag ggagggtcga aagactcaat
      241 cagacactac aatcacgcct gcctatcgaa ctggaacgaa acaagattca tacattggaa
      301 gaagccaata ctttccttct ttcctacatc caaaccttta atgaacagtt tggaaataag
      361 acaaaactct ctgtttttga ggaggctcct aacccctctg aacggaatct cattctagct
      421 agactggcgg agagagtcgt cgatagtgga caccatatcc gattccaaaa ccgttgctat
      481 attcctaccg aacaaggaaa agaagtctat ttcatcagaa agacgaaagc attagttcta
      541 aaagcatttg atggtgacat ctacctcaat atcgctgaca aaatctatca cacaaaggag
      601 ctactagatc atgaactcta ttcgaaaaac tttgaacaag aaccagaaca aaaaaaagaa
      661 agacgcaagt atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatac
      721 cttcataaaa acaaaaagga ttatgaagag tttactagtg aggagattca ttctcctcaa
      781 ctacaagtat aatctatttt tcgctaaatg ggaagctttt ccttaaagga agtcactc
//
LOCUS       DAVLBN010000143          828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLBN010000143 DAVLBN010000000
VERSION     DAVLBN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.143"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..828
                     /locus_tag="VXC24_002197"
                     /pseudo
     CDS             1..828
                     /locus_tag="VXC24_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT          301 a           73 c          176 g          278 t
ORIGIN      
        1 tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga taacatgcca
       61 tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt tttggacata
      121 ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaagatt ggagagtata
      181 ataaaaaata agaagataat tgcaataaat aacggaatta atgtatcaaa tagcgattta
      241 gatgtagtag gtgttcaaga ctttaaaaaa gaattttgta ttccaaataa caaaaaaatc
      301 atttgttata ttggaaggtt ggatccagaa aaaaggccgg atagattcct tgaatttgca
      361 gaaaaattat ttttagtcag agaagatgtg atttttatta tggctggaaa tggtagtatg
      421 tgggctgctt tgaaagaaaa aatttgccat ttgaaatgta gagataattt caggttactt
      481 ggtgaaatct atccagctac tatagtttac caaatatcgg atttattgta tattccttct
      541 gatacagaag gaatacctat gtgtgtttta gagtcaatgt cacaaggaac tccggtttta
      601 gctagtaatg ttggcgggtt aagtgaaatt attgaacata gggttgatgg atttttattt
      661 gagaaggaag atgttgaggg agtgtgtgct tgtgctaatt ttttactcaa tgattctgag
      721 tatttgaaat atataggtga gaatagtaaa tcaaaaataa gaaaacattt ttctgtgcaa
      781 aaaatgtttg tagaaaccat gagagtatat gatgaattat tagagaag
//
LOCUS       DAVLBN010000144          826 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLBN010000144 DAVLBN010000000
VERSION     DAVLBN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.144"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>826
                     /locus_tag="VXC24_002198"
     CDS             <1..>826
                     /locus_tag="VXC24_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494211.1"
                     /translation="TLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSFAM
                     VLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAGDS
                     AGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKGGG
                     GGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKTAL
                     DQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANGL"
BASE COUNT          240 a          155 c          223 g          208 t
ORIGIN      
        1 accttgtcta attctgtaaa tggtcgtatc agcctattta agtcgctgat gaaggacgca
       61 gcattgaacc ttggtaactc tatgttaccg attatcaatg ccattatgcc tgtcttgaac
      121 tcttttgcta tggtcttaaa gaacgttact gctaaactcg ctgagtttat cgctttgatg
      181 ttcaacaaga aagcaacagt gaaagatggt gttggtggag cagttggaga catgggtaac
      241 gccatgaagg atgctgcagg cggagcagga gaccttgctg acgcagtaga cgacgctgga
      301 gattcagcag gaggacttgc tgacaatctt ggagactccg ccaaaaacgc taagaaggcc
      361 gctaaagagt tgctaggtct tttgggattt gatgagatta acatcttgca aaaaccaaaa
      421 gatgacgacg caggcgggtc tggaggcggt ggcaaaggtg gtaaaggaaa gggaggcggt
      481 ggcggacctt tcaaagacat cttgccagaa gtcgagttga ccgacatgga caacaaattc
      541 aagagcattt ttgatggtct tggagataag ctcaaagggt tgtttgacct cttcaagaaa
      601 ggttttgatg cagcatttag accagaaggt atagaacgca ttaagactgc cttagaccaa
      661 atagctaaga caatgggaga aatcgccact gacccaaggg ttgtgaatgc ctttaaccga
      721 atggctgaga aaattgctta tgctttaggg caagtgacag gctcaataac aactatcggg
      781 ctaggtatcg gtgttttcct tgccgaaagt attgcaaatg gccttg
//
LOCUS       DAVLBN010000145          806 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLBN010000145 DAVLBN010000000
VERSION     DAVLBN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.145"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>806
                     /gene="phtD"
                     /locus_tag="VXC24_002199"
     CDS             <1..>806
                     /gene="phtD"
                     /locus_tag="VXC24_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0494212.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          285 a          160 c          180 g          181 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca agctgatacc aatcaaacgg aaaaaccaaa cgaggagaaa
      601 cctcagacag aaaaacctga ggaagataag gaacatgatg aagtaagtga gccaactcac
      661 cctgaatctg atgaaaaaga gaatcacgct ggtttaaatc cttcagcaga taatctttat
      721 aaaccaagca ctgatacgga agagacagag gaagaagctg aagatactac agatgaggct
      781 gaaattcctc aagtagagca ttctgt
//
LOCUS       DAVLBN010000146          741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLBN010000146 DAVLBN010000000
VERSION     DAVLBN010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.146"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>741)
                     /locus_tag="VXC24_002200"
     CDS             complement(<1..>741)
                     /locus_tag="VXC24_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0494213.1"
                     /translation="RVVQILNQCSNFIRKESDLEGVSDAVKSYYYNESNFESDELKEK
                     FLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDKKGSIEDSVLNIVFVTTRT
                     KYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREYIDYTLAENTISELANLDL
                     TKSYNQELIVTILKQFLKIEIERTETHEEKFTFGRYKVPDSEKLKQYHRSILKLLANL
                     YNIGSCETRFYIEKMLYDYRRKILTYSE"
BASE COUNT          245 a          124 c           80 g          292 t
ORIGIN      
        1 ctttctgaat aggtcaaaat ttttcttctg taatcatata gcattttctc aatataaaat
       61 ctagtttcac aactccctat attatacaaa ttcgctaaaa gttttagtat acttctatga
      121 tactgtttta atttttcact atccgggact ttatagcgcc caaaagtaaa tttctcttca
      181 tgagtctctg ttctttcgat ttcaatttta agaaactgct tcaaaattgt cacgattaat
      241 tcttggttat aacttttcgt caaatcaaga ttagcaagtt cagaaatggt attttcagct
      301 aaggtataat caatatattc tctttctgta accaacccgt agtttgcttc aagaatacta
      361 taaacctcag aaattttatt aggattttta tcaaagtact ttaacaataa ttggagaatt
      421 tgactacaat attttgtccg tgtagttaca aatacaatat ttaaaactga atcctcaata
      481 gatccctttt tatccttctg attaataaaa ttagtctttg tataaacctg agactctata
      541 ttatcaattt tatttttaac gtgtgaaatt gcttctaaag gaagtaatac tccaaattgt
      601 attaaaaact tttctttaag ttcatcactt tcaaaattac tttcattgta ataatatgat
      661 ttaactgcat cagaaacgcc ttctaaatca ctctctttcc taataaaatt ggaacattga
      721 tttagtattt gaacaactct t
//
LOCUS       DAVLBN010000147          679 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLBN010000147 DAVLBN010000000
VERSION     DAVLBN010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.147"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>679
                     /locus_tag="VXC24_002201"
     CDS             <1..>679
                     /locus_tag="VXC24_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV0494214.1"
                     /translation="LDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCPDCGSLMKKYD
                     FQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQ
                     KLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIA
                     QDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAK
                     IVLDRFH"
BASE COUNT          210 a          144 c          115 g          210 t
ORIGIN      
        1 tgctcgatat taaagaccca aacatcaaga ttctagatat catcaatatg gatacccaca
       61 aagaaattat cgctaagctg gattatgagg ctccatcttg ccctgattgt ggaagtctaa
      121 tgaagaaata tgactttcaa aaaccgtcta agatccctta cctcgaaaca actggtatgc
      181 cttctagaat tctccttaga aaacgccgtt tcaagtgcta tcactgttca aaaatgatgg
      241 ttgctgagac tcccctggta aagaaaaatc accaaatccc tcgtatcatc aaccaaaaaa
      301 ttgctcaaaa gttaattgaa aaaatttcta tgactgatat tgcccatcag ctggccattt
      361 caacttcaac tgtcattcgc aagctcaatg actttcactt tgagcatgat ttttctcggc
      421 ttccaaagat tatgtcttgg gatgagtatg ccttcactaa gggaaagatg agtttcattg
      481 cgcaagattt tgataatctt aatattatca ctgttcttga aggcagaaca caagctgtca
      541 tccgaaatca ctttcttcgc tacgatagag ccgttcgttg tcaagtgaaa atcattacga
      601 tggatatgtt tagtccttac tatgacttgg ctaaacagct ttttccgtgt gctaaaatcg
      661 ttctagatcg tttccatat
//
LOCUS       DAVLBN010000148          658 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLBN010000148 DAVLBN010000000
VERSION     DAVLBN010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.148"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>658
                     /locus_tag="VXC24_002202"
     CDS             <1..>658
                     /locus_tag="VXC24_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0494215.1"
                     /translation="RNLFLNSLFKQDISKTGIWTTSTYTAAIDSESKYLGHKALKIIG
                     LNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGY
                     KTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTIWIWMPKFEISDVDTS
                     YSEAPEDIEGQISTVESNFKQRADSLEAGVSRLTEGLRTKADISALNVTAENIRQSVK
                     S"
BASE COUNT          224 a          115 c          144 g          175 t
ORIGIN      
        1 cgaaatctat tcttgaactc actattcaag caggatattt caaaaacagg aatttggaca
       61 acgagtacat atacggctgc tatcgatagc gaaagtaagt atcttggaca caaggctctt
      121 aaaattatag gtttgaatcc atctggtcgt gatggaggta atcccaaggt tacttatcca
      181 gctctgggtc aattcgggaa agtaattccc ggaagtacga ctaatcaaga tgtaaccatt
      241 agtttttatg ctaaggcaaa taaaaatgga ataatgctaa gatctcgatt agggaatatc
      301 ggatataaaa ctggaaatgt gacattgtcg acagaaatta agcgatatgt tgtccatatt
      361 ccaaaaggtt ggacaaacga atccaagcag accacaaatg aatggttgtt caatttcaac
      421 caggaaggaa ccatttggat ttggatgccg aagtttgaaa taagcgatgt agatacttct
      481 tattcagaag ctcctgaaga tatagaaggt cagatttcaa cagttgaatc caactttaaa
      541 cagcgtgctg attcactcga agctggtgta agccgtctga ctgaagggct tagaactaaa
      601 gccgatatca gcgcactcaa cgtgactgct gagaatatta ggcaatctgt gaagagtc
//
LOCUS       DAVLBN010000149          651 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLBN010000149 DAVLBN010000000
VERSION     DAVLBN010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.149"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..525
                     /locus_tag="VXC24_002203"
                     /pseudo
     CDS             1..525
                     /locus_tag="VXC24_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          220 a          116 c          120 g          195 t
ORIGIN      
        1 actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc gctcaaagct
       61 atgggctaca ctcgaaaaaa aagaaccaca cctactatga acaagagcca gaaaaagtag
      121 ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag attgatgaaa
      181 caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt cagttaataa
      241 gaggcaaagt atctggaaga agatatcaga gaatttcttt ggttgcaggt ctaacaaatg
      301 aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga cttttttgaa
      361 gcttggtttc agaagtttct cttaccaaca ttaaccacac catcagttat tattatggat
      421 aatgcaagat tccatagaat gggtaagtta gaactcttgt gtgaagagtt tgggtataaa
      481 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgaggctct ataatatttg
      541 tagtgggtaa atcccctatg gatattatgg agcctatttt tgtgtagaaa aaaagtccca
      601 taagatctat aatgaaaagc gatcaaacaa ctcattagaa agattcatat g
//
LOCUS       DAVLBN010000150          642 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLBN010000150 DAVLBN010000000
VERSION     DAVLBN010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.150"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..584
                     /locus_tag="VXC24_002204"
     CDS             105..584
                     /locus_tag="VXC24_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0494216.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          242 a           82 c          149 g          169 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa ag
//
LOCUS       DAVLBN010000151          635 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLBN010000151 DAVLBN010000000
VERSION     DAVLBN010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.151"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..598
                     /locus_tag="VXC24_002205"
     CDS             <1..598
                     /locus_tag="VXC24_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0494217.1"
                     /translation="EYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKSTLL
                     RCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELRLGVKNFD
                     EEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSN
                     MIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          247 a           73 c          120 g          195 t
ORIGIN      
        1 agagtatcag ataaaaaatc ttagctacaa atttactgat gatgagtgtt taagcttaaa
       61 agatatttcg ttcaagcttg ggaaaattta tggcataata ggatccaacg gacgaggaaa
      121 atcaacgctt ttaagatgtt taataggtct tgagaaaaaa tcaaaagaag aaatttattt
      181 taagggagag aagctatcta aaaaagaaag actcaaaaac tcttcacttg ttatgcaaga
      241 tgtaaatcat caattattca cagatgaagt attcaacgag cttagattag gagtaaagaa
      301 ttttgatgaa gaaaaggcga aaatcatttt aaaagattta ggcctggacg aatttattga
      361 aaggcatccg atgagtttat caggagggca aaagcaaagg cttgcaatag catctgttat
      421 gtgcaagaat tctccatttg tcttttttga cgaaccttca agtggtatgg attattccaa
      481 tatgataaaa atatctgaac tgattaataa gtataaaacc atggataaaa taatttttat
      541 tgtttcccat gatatagaat ttttaaatga agtggcagat gaaatttttg aattgtaaaa
      601 tagagtctgt taaacatgtc tatagaactg gtaaa
//
LOCUS       DAVLBN010000152          598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLBN010000152 DAVLBN010000000
VERSION     DAVLBN010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.152"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..513
                     /locus_tag="VXC24_002206"
                     /pseudo
     CDS             1..513
                     /locus_tag="VXC24_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          224 a          105 c          105 g          164 t
ORIGIN      
        1 taaaccacca agtaaaagga acaaaaccaa gaaaagttga tagagataga cttaaaaact
       61 atcttactga caatccagac gcttatttga ctgaaatagc ttctgaattt ggctgtcatc
      121 caactaccat ccactatgcg ttcaaagcta tgggctacac tcgaaaaaaa gaaccacacc
      181 tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa tagattaaag
      241 cacctagcac ctgtttagat tgacgaaaca ggattcgata cttattttta tcgagaatat
      301 ggtcgctcat taaaaggtca gttaagaaga ggcaaagtat ctggaagaag atatcagagg
      361 atttctttgg ttgcaggtct aacaaatggt gagttaatcg ctccaataac ttacgaagag
      421 acgatgacga gcgacttttt tgaagtatgg tttcagaaat ttctcttacc aacattaaac
      481 acaccatcgg ttattatagt aaaacgaaat aagaatagga caaatcgatc aggacagtaa
      541 aatcgaattc taacaatgtt ttagaagtag atgtgtacta ttctagtttc aatctact
//
LOCUS       DAVLBN010000153          495 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVLBN010000153 DAVLBN010000000
VERSION     DAVLBN010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.153"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
BASE COUNT          172 a           87 c           68 g          168 t
ORIGIN      
        1 ttgttggaaa cagctaaacg tcatcaatta tagtgcgttg aatctataac agtacgcatc
       61 gactgctaaa atatttctat aaatcaattt tcctttccta atcgatttgt tcatatctta
      121 tttcaatcca ttataaatag cgagaaatat ctatcctatc ttctagaatg tcttccaaac
      181 gaggaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggac taaagttgta
      241 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt cactaatctg
      301 gagatttttc aatatacttc gttattgggc ggttacaatt tattatatga aaatcccata
      361 tcattctcca attctatatt ttacctttct aaatgtatag attaactacc taattatatc
      421 atataacgca gattcctttc aatcgtatga tttactgcat taaattaagt aaaaaaataa
      481 aggcagtccg aagac
//
LOCUS       DAVLBN010000154          452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVLBN010000154 DAVLBN010000000
VERSION     DAVLBN010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.154"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..452
                     /locus_tag="VXC24_002207"
                     /pseudo
     CDS             1..452
                     /locus_tag="VXC24_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          166 a           90 c           73 g          123 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaac acttgatgaa gtactcaatt tacaagctaa aacgcgacag
      241 aaacgaaaat attcttctca taaaggagac gttggcaaga aagcagagaa tctcattcaa
      301 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      361 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      421 attatcgcct ataatctttc aacttcaccc aa
//
LOCUS       DAVLBN010000155          438 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVLBN010000155 DAVLBN010000000
VERSION     DAVLBN010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.155"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            277..>438
                     /locus_tag="VXC24_002208"
     rRNA            277..>438
                     /locus_tag="VXC24_002208"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a           72 c          114 g          100 t
ORIGIN      
        1 acgggttcga atcccgtacg gactatggta tgttgcggtt ggaacacttg atgaaaaaaa
       61 gtttaaaaaa acttaaaaat cttcaaaaaa gtgttgacaa gcgaaagcag ttgtgatata
      121 ctaatatagt tgtcgcttga gagaagcaag tgacaaagac ctttgaaaac tgaacaagac
      181 gaaccaatgt gcagggcgct acaacataag ttgtagtact gaacaatgaa aaaacaataa
      241 atctgtcagt gacagaaatg agtgagaact caaactttta atgagagttt gatcctggct
      301 caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag gaggagcttg
      361 cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct ggtagcgggg
      421 gataactatt ggaaacga
//
LOCUS       DAVLBN010000156          382 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.156, whole genome shotgun sequence.
ACCESSION   DAVLBN010000156 DAVLBN010000000
VERSION     DAVLBN010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.156"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>382)
                     /locus_tag="VXC24_002209"
     CDS             complement(<1..>382)
                     /locus_tag="VXC24_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0494218.1"
                     /translation="ANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSD
                     RRLKENITDTAVKALDKINRLRMVA"
BASE COUNT          101 a          105 c           56 g          120 t
ORIGIN      
        1 gcaaccattc ttaatctgtt gattttgtcc aaggctttca cagctgtatc tgtgatgttc
       61 tcttttaagc gtctgtctga tttttgttcc atccaatact tcacgctacc gctaccgacc
      121 tgattccacc aaacaaccgc attccttccg cctttgggat tccaaccatc accaagcaca
      181 tctttacttc caagttcgat accatttgaa aacacaggag aacgagaaaa agtagtattc
      241 ccatagaagt ttgctctcga tgaattcgaa aaatccactt gatcataaaa accgacttca
      301 ttcctacagt acattttccc atcagtattg acgttccatg ctttaggtcc ggcatagttc
      361 caattatttc cccagttcgc cc
//
LOCUS       DAVLBN010000157          351 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.157, whole genome shotgun sequence.
ACCESSION   DAVLBN010000157 DAVLBN010000000
VERSION     DAVLBN010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.157"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..225)
                     /locus_tag="VXC24_002210"
     CDS             complement(34..225)
                     /locus_tag="VXC24_002210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0494219.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
BASE COUNT          107 a           61 c           67 g          116 t
ORIGIN      
        1 attttcagat agactcagaa gaatttaagc gtcttagcta tgaagccatt catgatactt
       61 ctcaagtaac tcaatagtag ttattacaga agtcaaacca ctgaccttcc ccagttgcaa
      121 tccgtctgta tggtcaatct gtttagtagc ttcattagct ttagcagaga tagcttgcat
      181 atcttcagct gttaaagatt ctcgaaaatc tttaaaggat ttcataaaaa ctcctccttt
      241 ctattggaat tttgactaaa acggtgagag gtcctagtcg agattattat agcaatttag
      301 gaggatatta catcggtctt gaggctgatt tttggaggca atattggaag a
//
LOCUS       DAVLBN010000158          337 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.158, whole genome shotgun sequence.
ACCESSION   DAVLBN010000158 DAVLBN010000000
VERSION     DAVLBN010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.158"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
BASE COUNT          115 a           62 c           49 g          111 t
ORIGIN      
        1 acgaatagag gtatttaacc ttttaccgcc accagtgctg tcattattaa ttccagcaga
       61 ggcgttttct ttctcaagct cactagttgt atccgaaccc caacgcggca acgttaaatc
      121 ataatttcca atctgtctag ctaaaactgt agggagaaac aaactagatg caattgtaac
      181 tacgcaaaaa aggaatatat ttttcttctt ttcatgatat cgtcctccta agaagtgata
      241 aacaagatag ttgattgatc aatttgatac atattacatt ttcattatat caataaaaga
      301 aagcgttgtc aatcatttta tttaaaatat tgtcata
//
LOCUS       DAVLBN010000159          334 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00035635
            SAMN33606850-rid17953303.denovo.159, whole genome shotgun sequence.
ACCESSION   DAVLBN010000159 DAVLBN010000000
VERSION     DAVLBN010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606850
            Sequence Read Archive: SRR23726117
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721994.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721994.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:13:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,211
            CDSs (total)                      :: 2,164
            Genes (coding)                    :: 2,027
            CDSs (with protein)               :: 2,027
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 74 of 137
            Pseudo Genes (incomplete)         :: 58 of 137
            Pseudo Genes (internal stop)      :: 36 of 137
            Pseudo Genes (multiple problems)  :: 26 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606850-rid17953303.denovo.159"
                     /strain="AUSMDU00035635"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>334
                     /locus_tag="VXC24_002211"
     CDS             <1..>334
                     /locus_tag="VXC24_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEV0494220.1"
                     /translation="ETYKPNVLHFCELLAEEEGIKLSDTTVRKILYKKNILSPKSHRK
                     TKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSRPRKKFAGELIQMDASPHAW
                     FGPETTNL"
BASE COUNT          130 a           76 c           55 g           73 t
ORIGIN      
        1 atgaaacata taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa
       61 ttaagctctc tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta
      121 agtctcacag aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac
      181 ccctagacaa tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac
      241 atcctagtag acccagaaag aaatttgctg gagaactcat tcaaatggat gccagccctc
      301 atgcctggtt tggaccagaa accaccaact taca
//
